<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="http://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS86</accession>
    <name>A0A010YS86_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="6">2.7.8.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Phosphatidylglycerophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">SacsacDRAFT_0035</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">This protein catalyzes the committed step to the synthesis of the acidic phospholipids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60110"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="6"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282217.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.35"/>
    <dbReference type="HOGENOM" id="CLU_051314_2_3_9"/>
    <dbReference type="OrthoDB" id="1702107at2"/>
    <dbReference type="UniPathway" id="UPA00084">
        <property type="reaction ID" value="UER00503"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006655">
        <property type="term" value="P:phosphatidylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00560">
        <property type="entry name" value="pgsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EXG83070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="191" mass="20905" checksum="F20E3F78E323B8C8" modified="2014-06-11" version="1">MNLPNRITLSRIFMIPIMMVFLLVDLPFLPEPLVWGGVELGWGQLIACIIFIIASCTDGIDGYIARSRNLVTNLGKLMDPLADKLLVSAAFISLVQMDKLAAWMAIVIISREFAVTGLRQIALLDGSVMAAGAGGKIKTVLQIVAISLLLLNNLPFEMWGIPAADIFAWAAVIVTAYTGVDYFVRNRRLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSC4</accession>
    <name>A0A010YSC4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative periplasmic solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282311.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.71"/>
    <dbReference type="HOGENOM" id="CLU_113290_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="240" mass="24881" checksum="69DA787B682765DD" modified="2014-06-11" version="1">MFKNRSFMLGLGIGIITGALLLQLMLLAQSGRPTTPADVESTNEVQTNAPAGEGEQPTEEQPSDSSDAEETPTDASEPQDSTEEPTEPEAAAPTEPDSEAAEAPETGQAPASSEPEEPAAATTEAPTAPTEPTDTATTGSDQPAQAPVVPTEPEASADVEPQQSSAVESSNVSFEIERGMNLKAVSQALENAGVVDDAVDFQRQAAEAGVTGKLQIGNYSFKSGDSYADIIREISTSKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSG3</accession>
    <name>A0A010YSG3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar protein export ATPase FliI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282377.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.101"/>
    <dbReference type="HOGENOM" id="CLU_022398_5_1_9"/>
    <dbReference type="OrthoDB" id="875807at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005714">
        <property type="entry name" value="ATPase_T3SS_FliI/YscN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022425">
        <property type="entry name" value="FliI_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040627">
        <property type="entry name" value="T3SS_ATPase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18269">
        <property type="entry name" value="T3SS_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03497">
        <property type="entry name" value="FliI_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01026">
        <property type="entry name" value="fliI_yscN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="159"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="439" mass="47490" checksum="C079D28090333BF2" modified="2014-06-11" version="1">MKEILVDKYLDQLRQIDPIRVNGKVTQVIGLMVESEGPDASVGEVCYIYPTKTAPPLQAEVVGFRENKVLLMPLGELQSIGPGCDVVGTGKPLTVQVGSELLGKVLDGLGRPLDGSMLPARMAHASTFNTPSNPLQRPRVHEPINVGVRAIDGLLTIGKGQRVGIFAGSGVGKSTLMGMIARNTSADINVIALVGERGREVLDFIERDLGPEGLARSVVIVATSDQPALVRIKAALIATSIAEYYRDRGMNVMMMMDSVTRFAMAQREVGLAVGEPPAMRGYTPSVFATLPKLLERAGTGPTGSITAFYTVLVDGDDMNEPIADAVRGILDGHIVLNRGIANRGHFPAIDVLASISRVMKDISPEIQTDAANNLKRLLSVYKESEDLINIGAYQRGSSAEIDEAIENIQRIWDFTKQKVDEKTTLDETIERLIQEFSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSH0</accession>
    <name>A0A010YSH0_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Flagellar basal-body rod protein FlgC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0105</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4 5">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282389.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.106"/>
    <dbReference type="HOGENOM" id="CLU_123272_0_0_9"/>
    <dbReference type="OrthoDB" id="1870921at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006299">
        <property type="entry name" value="FlgC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01395">
        <property type="entry name" value="FlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="6">
        <location>
            <begin position="7"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="7">
        <location>
            <begin position="100"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="150" mass="16118" checksum="4E1A40EA27DE32EA" modified="2014-06-11" version="1">MRISNGFDVSASALTAQRLRMDIISSNIANADTTRAQVVDGQVQPYRRKVAVLAENNQTPFAQTLNAAMGGKSSASGVKVTGIKEDQEPFKLVYNPTHPDANADGYVQMPNVDIAKEMVDMISATRSYEANVTALNATKAMITKALQIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSM3</accession>
    <name>A0A010YSM3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3204932_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="45" mass="5042" checksum="7ABF4DB56EDA3E64" modified="2014-06-11" version="1">MLIAAFHLARINGQTVSPETTMFSTFVRSVKKYSGKSRTKVYSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSN0</accession>
    <name>A0A010YSN0_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gluconolactonase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMP-30/CGR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506755.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.151"/>
    <dbReference type="HOGENOM" id="CLU_036110_3_2_9"/>
    <dbReference type="OrthoDB" id="852341at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGL" evidence="2">
        <location>
            <begin position="19"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="300" mass="33319" checksum="8966F414D3C0FB8B" modified="2014-06-11" version="1">MHELKDIQLQPASDYRATLGEGPCWLEDKQALMWVDIEGKQLRFYYPGDGREEVYELPERAGAAVGFSDRKVVLALESGFAYYDLDTRETTPIHDPENREDNRFNDGKCDAAGRFWAGTMSLVGKDKQGGFYCLDRDLSVRHIFGDVSTSNGLGWSPDGTVMYYIDTGTRKVQAFEFDVDAGTLGAERTVVSFEHEEGWPDGMTVDADGNLWIAHYGGSRVSKWDPVAGLKLEEIMLPAQNVTSCAFGGTDYRELYITTAADGVSDEDRAKLPLTGALFVCRPGAQGQPMHVFRPQSNQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSV1</accession>
    <name>A0A010YSV1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506763.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1440119_0_0_9"/>
    <dbReference type="OrthoDB" id="992687at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="188" mass="21128" checksum="C7FA180558F2EAC8" modified="2014-06-11" version="1">MKILLQLSDTENFTTNEKSIARYILLHRERMLNLSMRELAQETYTSHSTVNRLTRKLGLSGFRAFMLGLAAEFQQENGTAGPIDPNYPFGLDESPAQIARHLIANHIPFLTITSAASSPLAQLSPIVIRVPGDEKKHAKIGPFASQIAFEYVLNVLYSCIYKLAYAKNRDSAIERLQQAYIREAISDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT01</accession>
    <name>A0A010YT01_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506774.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_34_4_9"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="164" mass="18588" checksum="79336F23D9306AF2" modified="2014-06-11" version="1">MNQKASGRADYAIRDEIEGDAGRLIELFGQLGYPVSEEELSLRLTALRRREDYAIRVAERDRKLIGMIAFHSEMALLQPTCEVRVMALVVAEQERGSGIGGRLLAEAEDWARDRNASYMRLNSGIREERSKAHIFYRSRGYDSGSIGFSKKLRTDSERQSAKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT04</accession>
    <name>A0A010YT04_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.269"/>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="7">
        <location>
            <begin position="134"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="134"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="233" mass="27022" checksum="F746B59664D98355" modified="2014-06-11" version="1">MNDPKTILIADDNNEIREIVRVLLESENYEVIEAVDGEDAVNKVTEQVDLIILDIMMPVKSGFKACIDIREKTSAPILFLTAKTQDSDKYMAFSVGSDDYMSKPFSYTELVYRVKALLRRYYVYRGKEKTAASSNLIQIRDLSINTDSHEVTIDGKEIVLTDIEYQILLLMAQNQRKIFSAQNLYESVWEEPYFYSCNNTVMVHIRNLRKKTEHDPQEPKLIKTVWGKGYRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT07</accession>
    <name>A0A010YT07_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282656.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.275"/>
    <dbReference type="HOGENOM" id="CLU_082381_1_0_9"/>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="66"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="205" mass="23381" checksum="6935C63553986244" modified="2014-06-11" version="1">MQPKWLEWAKQIQAISQAGLEYSRDVYDLERFEMLRTISLEIMHEYTGVETAQLRELFAGETGYATPKVDVRGVIFQENKVLLVRERLDGAWSLPGGWADIGLSAKENVVKEIAEETGYAAEAGRLLAVLDKKFHDHPVSPFHVYKMFIHCEITGGEATATMETSEVGFFGEEDLPPLSIERNTEHQVKTMFEYLRNPERAVWVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6U7</accession>
    <name>A0A010Z6U7_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex</fullName>
            <ecNumber evidence="6 11">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">SacsacDRAFT_0003</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA</text>
            <dbReference type="Rhea" id="RHEA:15213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10582"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="2.3.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="11">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="6 11"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282150.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.3"/>
    <dbReference type="HOGENOM" id="CLU_016733_0_0_9"/>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="UniPathway" id="UPA00868">
        <property type="reaction ID" value="UER00840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033512">
        <property type="term" value="P:L-lysine catabolic process to acetyl-CoA via saccharopine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 11" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 11" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="13">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="14">
        <location>
            <begin position="133"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="77"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="168"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXG83038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="435" mass="46289" checksum="563ADDA4650A4789" modified="2014-06-11" version="1">MSDIKVPEMGESVTEGTILRWTVAEGDAVQQGDVLLELETDKVNLEVSAESSGLIETRLRQEGDTVQVGEVIGRIRTGDAASSTTGTASAPKGEESPAAAAEASAPSASLPESPKAAEAASPPPAENGDAGTKASPAARKLARERGVELGSVPSADPIGRVYSGDVKSFAEGAPTSQPQAAPQPQAAPPKAPPKAPAAVDPLKPVERQRMSRRRQTIATRLVEAQHNAAMLTTFNEVDMTAILDVRKRRKDNFKQKFDVNLGFMSFFTKAVVGALKAFPAVNAEIDGDEVVYKKFYDIGIAVSAKEGLVVPVVRNADRLGFAEIEKSIAGLATKARDNQLALSDLQGGTFTITNGGVFGSLLSTPILNAPQVGILGMHKIQLRPVAIDEERMENRPMMYIALSYDHRIIDGSEAVRFLVKVKELLEDPESLLIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6V6</accession>
    <name>A0A010Z6V6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC-type multidrug transport system, ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">SacsacDRAFT_0013</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282169.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.13"/>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_9"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="20"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="337"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="371"/>
            <end position="378"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG83048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="590" mass="66140" checksum="782CA23274C33734" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6W3</accession>
    <name>A0A010Z6W3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nicotinamidase-like amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282190.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.23"/>
    <dbReference type="HOGENOM" id="CLU_068979_12_1_9"/>
    <dbReference type="OrthoDB" id="1442962at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="184" mass="20235" checksum="8F4E84FA955584A5" modified="2014-06-11" version="1">MRALIVIDYTNDFVDGSLPVGQPAIEIEQRMIDLTTQFASNGDYAVMAVDLHEQNDPHHPESTLFPPHNIRGTAGRELYGGLKAAYEQNEEHIYWMDKTRYSAFAGTDLALRLRARGIAEVHLIGVCTDICVLHTAMDAYNHGFEIVVHEDAVASFNAAGHDWALGHFTGSLGAKVVSGWQVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6Y1</accession>
    <name>A0A010Z6Y1_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Ribonuclease J</fullName>
            <shortName evidence="9">RNase J</shortName>
            <ecNumber evidence="9 10">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rnj</name>
        <name evidence="13" type="ORF">SacsacDRAFT_0043</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, may be a subunit of the RNA degradosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9 10"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282241.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.43"/>
    <dbReference type="HOGENOM" id="CLU_008727_3_1_9"/>
    <dbReference type="OrthoDB" id="580619at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01491">
        <property type="entry name" value="RNase_J_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004613">
        <property type="entry name" value="RNase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030854">
        <property type="entry name" value="RNase_J_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041636">
        <property type="entry name" value="RNase_J_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001587">
        <property type="entry name" value="RNase_J_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17770">
        <property type="entry name" value="RNase_J_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004803">
        <property type="entry name" value="RnjA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00649">
        <property type="entry name" value="MG423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01292">
        <property type="entry name" value="UPF0036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 9 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="12">
        <location>
            <begin position="23"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 11">
        <location>
            <begin position="369"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR004803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR004803-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG83078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="560" mass="61259" checksum="D78A55E122A8C86D" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6Z5</accession>
    <name>A0A010Z6Z5_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription termination/antitermination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nusA</name>
        <name evidence="10" type="ORF">SacsacDRAFT_0058</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Participates in both transcription termination and antitermination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282278.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.58"/>
    <dbReference type="HOGENOM" id="CLU_029242_2_2_9"/>
    <dbReference type="OrthoDB" id="384865at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_B">
        <property type="entry name" value="NusA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036555">
        <property type="entry name" value="NusA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013735">
        <property type="entry name" value="TF_NusA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010213">
        <property type="entry name" value="Tscrpt_termination_fac_NusA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08529">
        <property type="entry name" value="NusA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69705">
        <property type="entry name" value="SSF69705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01953">
        <property type="entry name" value="NusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="5 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 7" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="S1 motif" evidence="9">
        <location>
            <begin position="135"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG83093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="365" mass="40985" checksum="B70997D6FD8F684D" modified="2014-06-11" version="1">MSTDFIEALNELERDRGISKEILFEAIEAALISSYKRNFNTAQNVRVDMNRNTGVIKVYARKLVAEEVLDDRTEISLENAREINPHLQIDDIAELEVTPRDFGRIAAQTAKQVVTQRIREAERGLIYNAFVDKTEDIVTGTVQRMDARNLYVDLGKIEAALPLTELMPGEKFAHNERIKGYITKVENTTKGPQIILSRTHPGLLKRLFELEVPEIFDGVVEIKSVAREAGFRSKIAVYSRNAEVDPVGSCVGPKGVRVQTIVNELRGEKIDIVNYSESVEEYVANALSPSKVIEVEVFEAEKMARVIVPDYQLSLAIGIKGQNARLAAKLTGWKIDIKSETQAEEEFGRERTYDGEMPQDSVSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z752</accession>
    <name>A0A010Z752_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent protease ATPase subunit HslU</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Unfoldase HslU</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hslU</name>
        <name evidence="9" type="ORF">SacsacDRAFT_0108</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ClpX chaperone family. HslU subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282394.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.108"/>
    <dbReference type="HOGENOM" id="CLU_033123_0_0_9"/>
    <dbReference type="OrthoDB" id="718259at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036402">
        <property type="term" value="F:proteasome-activating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00249">
        <property type="entry name" value="HslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004491">
        <property type="entry name" value="HslU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF3">
        <property type="entry name" value="PTHR48102:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00390">
        <property type="entry name" value="hslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="51"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="ClpB_D2-small" evidence="8">
        <location>
            <begin position="361"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="62"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG83143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="469" mass="52911" checksum="656E05495070019A" modified="2014-06-11" version="1">MKNEALTPREIVAELDKYIVGQKKAKRSVAVALRNRYRRSLLPEETRDEVAPKNILMIGPTGVGKTEIARRLAKLVGAPFIKVEATKFTEVGYVGRDVESMVRDLVETSIRMVKAERTEKVKDRAEEMANERIVEILVPAAKSSSAQRNPFEMLFGGQSKTTPEPEPEKTRYEEGSLSERRRQVRFNLLSGKLEDDIIEIDVEDAMPNMFDMLAGQGNDQMGMNIQEMLGNFMPKRTKRRKLPIREARKALTQEEASKLIDMDDVNQEAVRRAEQAGIIFIDEIDKVAGSGRGHGPDVSREGVQRDILPIVEGSTIVTKYGPVKTDYILFMAAGAFHVSKPSDLIPELQGRFPIRVELESLTLEDFIAILTEPQNALTKQYTDLLKTENIEIGFSKEAIHEIASIAASVNQNTENIGARRLHTILEKLLEDLSFEAPELNLEQMMITPEYVREKLDDIAKDRDLSQYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z768</accession>
    <name>A0A010Z768_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein, cytoplasmic domain of flagellar protein FhlB like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282414.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.118"/>
    <dbReference type="HOGENOM" id="CLU_041013_4_2_9"/>
    <dbReference type="OrthoDB" id="1823885at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="99" mass="10714" checksum="338667E488191E93" modified="2014-06-11" version="1">MKETKSEETARKRAVALKYAPEQMSAPVVVAKGSGSIAESILARAQEAGVPIQEDAALVEVLSKLDLDQQIPAELYGLVAELLSFVYRSDREAGRRKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z776</accession>
    <name>A0A010Z776_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6 7">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplS</name>
        <name evidence="8" type="ORF">SacsacDRAFT_0123</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6 7">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282428.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.123"/>
    <dbReference type="HOGENOM" id="CLU_103507_2_1_9"/>
    <dbReference type="OrthoDB" id="1698718at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="114" mass="13167" checksum="E48BA0248F956322" modified="2014-06-11" version="1">MNLIQALTQEQLRKDIPSFRPGDTLKVHVKVIEGTRERIQLFEGVVIKRKGGGIAETFTVRKISYGVGVERTFPINSPKLDKIEVVRHGKVRRAKLYYLRELRGKAARIKEIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7A7</accession>
    <name>A0A010Z7A7_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmF</name>
        <name evidence="5" type="ORF">SacsacDRAFT_0143</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_018975076.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.144"/>
    <dbReference type="HOGENOM" id="CLU_129084_1_3_9"/>
    <dbReference type="OrthoDB" id="2092354at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG83178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="57" mass="6584" checksum="25F117E3D0F6BE33" modified="2014-06-11" version="1">MAVPQRRTSKTRRDKRRTHFKLAVPGMVKCEQCGELKLAHHVCKVCGTYKSREVISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7D4</accession>
    <name>A0A010Z7D4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.165"/>
    <dbReference type="HOGENOM" id="CLU_083287_27_4_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="20"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="162" mass="18798" checksum="7FF62824AA887FB4" modified="2014-06-11" version="1">MDERARKSEELPHEDTKKLINQFLGSWMAIEREMGSVVRRQMPVDLTNDQYYLLQHIMQFGPRTSSELADTFKVVKSSITAIVTRLVDRGLIERTRSEEDRRTVYLSLTDRGQQIAEQVERRISESVGSYLSHFEEKEISMVMAAFEKLAELVIEDGGREKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7E4</accession>
    <name>A0A010Z7E4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, ribosomal protein N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_2_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="212" mass="24698" checksum="84A47EC218510954" modified="2014-06-11" version="1">MEKKTAGPFFADLSADHSAAATILEGDRVTLRSVTPDDYRELYDLEYGSEDRAWTDWDAPYYKDEEKQETFEEFAQGYEKMKEAKLHWEPRLLIETKEGVMLGVVTSYWEHKPSNWLESGIVLYRSDTWSRGCGTEALRLYVGYLFASLDVPRVGITTWSGNERMMRAAARIGMRIEGRMRRCRIVRGELYDSIRMGVLREEWEELHGSSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7F1</accession>
    <name>A0A010Z7F1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282514.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048109_0_1_9"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="132"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="270" mass="29672" checksum="484402351501AED4" modified="2014-06-11" version="1">MMPFEQITDRLERARLLEQLTIEAWPPTVLESLAGWKLRAANGVSRRANSVWAVGPFPGVEKDWLAQAEAFAARHGIDPCFYVSETSPTGLDEQLSLAGYTLSELCYLMAGSAALALERIAARPAVEQSGEITISLPRSNQTPENEEWLQQFMTLKNVPAERSAIYASIFDGIQADKCFASLRIGGEVAALGTVVSQGNFGYISNLTVAPNYRRRGLAARMTAELARWAVERGAAELYLQVLQNNAAAVALYQALGFEVVARHHYRVLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7H9</accession>
    <name>A0A010Z7H9_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0193</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282548.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.199"/>
    <dbReference type="HOGENOM" id="CLU_010312_4_0_9"/>
    <dbReference type="OrthoDB" id="114076at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="212"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="233"/>
            <end position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="786" mass="91331" checksum="62AAB5AA9538C67D" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7M8</accession>
    <name>A0A010Z7M8_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282590.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.228"/>
    <dbReference type="HOGENOM" id="CLU_369970_0_0_9"/>
    <dbReference type="OrthoDB" id="108769at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="775" mass="85181" checksum="F13B6B475680AE24" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7N5</accession>
    <name>A0A010Z7N5_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="3">2.3.3.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">SacsacDRAFT_0228</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19268</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="3"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.239"/>
    <dbReference type="HOGENOM" id="CLU_022158_0_1_9"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005671">
        <property type="entry name" value="LeuA_bact_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00973">
        <property type="entry name" value="leuA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="8">
        <location>
            <begin position="10"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG83263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="523" mass="57052" checksum="A6B092AA7086BEE7" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7N9</accession>
    <name>A0A010Z7N9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506769.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168188_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="127" mass="14333" checksum="FFC751ABCF6814C2" modified="2014-06-11" version="1">MMHEASSKERVVTMEKQIQALNEWLTSKVGQTLQIEKQESGDTDIVHFELREIGERSQDNPVDDYLERALLLHGSGSIVNGDGESVPLPGDTYEIVLNELEIGKQDDRQLSLKNDRADYTLSIDLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7P3</accession>
    <name>A0A010Z7P3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC-type multidrug transport system, ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">SacsacDRAFT_0238</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282622.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.250"/>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_9"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="16"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="332"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="367"/>
            <end position="374"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG83273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="578" mass="63370" checksum="A230383064962022" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7P6</accession>
    <name>A0A010Z7P6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, ribosomal protein N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506771.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_0_9"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="199" mass="23085" checksum="A1FE94CC05D24034" modified="2014-06-11" version="1">MTKSFDPILLDFPEQFETPRLIVRATRPGDGAELNAAIRESREELVPFMPFARVLPEPEATEAMVRRRRLHFLERTDMMMLMTERGTGKILGSSGLHRFDWNARRFEIGYWIRTSYAGQGLVTEAVRGLTEFADRELNANRVEIRCDDRNERSAAVAKRAGFTLEGVLRNWKREEDGTLVNEMVFSKVHPCRKRRIIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7Q4</accession>
    <name>A0A010Z7Q4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type antimicrobial peptide transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">SacsacDRAFT_0253</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282645.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.267"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_9"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG83288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="234" mass="25712" checksum="59EF855366297152" modified="2014-06-11" version="1">MIEIRNVVKRYFAGTPNEITVLDGIDLHIASGEFVAIVGQSGSGKSTLMNIIGALDQPSSGEYELGGTPIQRMNRDELAQIRNQKIGFVFQSFNLIPRNSALKNVELPMVYAGVKPAERQRRAKELLTMMGMDERMDHQPNELSGGQKQRVAIARALANNPDIILADEPTGALDSKTGNLVMDIFLRIHREEKKTILFITHSTELAELCPRVVTVKDGRIVSDKAGSNRGGTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7S4</accession>
    <name>A0A010Z7S4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0279</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282693.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.296"/>
    <dbReference type="HOGENOM" id="CLU_000445_30_3_9"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="9"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="7">
        <location>
            <begin position="135"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="135"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="233" mass="26167" checksum="6620A6C4F44E5650" modified="2014-06-11" version="1">MQKDGQNQQILIVEDDESINSIIRDGLTRVGFLCTSAYSGTEGLMRLDQQSYRLIVLDLMLPGLSGEAFMRQIRSEAGLAVPVIVLTAKDHLDHKLNLFALGADDYVTKPFELEELIARIRVHIGKSASSADPAPQAYRHKNLTLDCGAYSACINGTPLALTRQEYKILELLVKHPTRVFTKQDLYELAWDDVYLGEDKTITVHISNIRNKIKTYDPEPYIDTLWGIGFRLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWK4</accession>
    <name>A0A010ZWK4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC-type multidrug transport system, ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">SacsacDRAFT_0014</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282171.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.14"/>
    <dbReference type="HOGENOM" id="CLU_000604_84_7_9"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="35"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="447"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="479"/>
            <end position="486"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG83049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="711" mass="78753" checksum="AD3E09418DFB34A8" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWL3</accession>
    <name>A0A010ZWL3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282192.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.24"/>
    <dbReference type="HOGENOM" id="CLU_037162_3_1_9"/>
    <dbReference type="OrthoDB" id="1846332at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="38"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="261" mass="30382" checksum="079DADD96143FA80" modified="2014-06-11" version="1">MVMPMNEQDEQKKYDAKKYRTPDGAPADIVMFTLTKKERKTVTKTLPLRELRVMLIRRRSWPFAGKWALPGGFSRDDESLYETALRELKEETGVVGRHLEYLSVYSDPGRDPRGWIISHAFFALVEEEVLEKRQAADDAEEVGLFTIEEALDELDLGFDHRDIIADAYRRIQEKMLKTTIARKFLPQEFTLSELYQVIKAVVPDFEEPNFIRKITSTRSRKGILEEVRDENGVPISSNQYSQRPAQLYRFLDNVPRLSIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWM7</accession>
    <name>A0A010ZWM7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.39"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="258" mass="27475" checksum="5464A9DA47489870" modified="2014-06-11" version="1">MMEDAEKKGRRKPSDSCVLVTGASGGIGSAIAERFALDGCRIALHYSTSEEAVRSVADRCISLGAAQVWTARADISKRAEVLRMRDELKAEGFVPNVLVNNAGVAHYGMLQDVTDEEWDHVMNVNLKGTFLCCQAFMDAMVSGKYGRIINMSSVWGLSGASCEVIYSTAKGGINAFTKALAKELALSGVSVNAVAPGAVRTAMLDTLSAEELNALAEEIPVGRLAEPRDIAETVHFLALPECGYMTGQILSPNGGWIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWN2</accession>
    <name>A0A010ZWN2_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapA</name>
        <name evidence="11" type="ORF">SacsacDRAFT_0044</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282244.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.44"/>
    <dbReference type="HOGENOM" id="CLU_049343_7_1_9"/>
    <dbReference type="OrthoDB" id="1438588at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG83079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="294" mass="31320" checksum="26562030A5B35AA4" modified="2014-06-11" version="1">MEFGRLITAMVTPFDKQGEVAWDQVPALIDMLIEQQRTESIVVFGTTGESPTLTDEEKIQLLEVSVRHAAGRCKIIAGTGSNDTHHSIELSQAAERAGADGLLLVVPYYNRPNQAGLYAHFSAIAQATSLPVMLYNVPSRTASNLEGATTLRLAQLPNVVAVKECASMDQVAYIAANAPEGFRIYSGDDAASLPALSVGAYGIVSVASHVVGAKMSEMLTAHAGGNAGEATRIYHSLLPVFKGLFACPHPVPNPVAIKYALTLRGLQVGGVRLPLVDATEDEKSYIQHFMADFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWN6</accession>
    <name>A0A010ZWN6_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Polynucleotide phosphorylase</fullName>
            <shortName evidence="6">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pnp</name>
        <name evidence="8" type="ORF">SacsacDRAFT_0049</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="6"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282258.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.49"/>
    <dbReference type="HOGENOM" id="CLU_004217_2_2_9"/>
    <dbReference type="OrthoDB" id="122725at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="621"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="700" mass="76134" checksum="839334B887C600AB" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWP3</accession>
    <name>A0A010ZWP3_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome maturation factor RimP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rimP</name>
        <name evidence="6" type="ORF">SacsacDRAFT_0059</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of 30S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RimP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282280.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.59"/>
    <dbReference type="HOGENOM" id="CLU_070525_2_0_9"/>
    <dbReference type="OrthoDB" id="1595498at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01734">
        <property type="entry name" value="YlxS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01077">
        <property type="entry name" value="RimP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003728">
        <property type="entry name" value="Ribosome_maturation_RimP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028998">
        <property type="entry name" value="RimP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036847">
        <property type="entry name" value="RimP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028989">
        <property type="entry name" value="RimP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035956">
        <property type="entry name" value="RimP_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33867">
        <property type="entry name" value="PTHR33867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02576">
        <property type="entry name" value="DUF150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17384">
        <property type="entry name" value="DUF150_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74942">
        <property type="entry name" value="SSF74942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75420">
        <property type="entry name" value="SSF75420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="DUF150" evidence="4">
        <location>
            <begin position="13"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="DUF150_C" evidence="5">
        <location>
            <begin position="88"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG83094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="153" mass="17092" checksum="21DE4CEDD10D9BB6" modified="2014-06-11" version="1">MSTPKIKTTVEEMIEPYLTEQGFELVDVEYVKEGGSYFLRIYVDKEGGIDIDDCGQISEYMSQKLDENDPIEEAYFLEVSSPGAERPLKKAEDVLKAVGKDVFVTTYEPINGSKEFEGKLLSFENGELVIAFGKKQAAVPYDKVASARLAIIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWR7</accession>
    <name>A0A010ZWR7_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chemotaxis protein CheA</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">SacsacDRAFT_0079</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282332.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.80"/>
    <dbReference type="HOGENOM" id="CLU_000650_3_6_9"/>
    <dbReference type="OrthoDB" id="305000at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037006">
        <property type="entry name" value="CheA-like_homodim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037052">
        <property type="entry name" value="CheA-like_P2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010808">
        <property type="entry name" value="CheA_P2-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035891">
        <property type="entry name" value="CheY-binding_CheA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07194">
        <property type="entry name" value="P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01231">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55052">
        <property type="entry name" value="SSF55052"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HPt" evidence="13">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="311"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="12">
        <location>
            <begin position="563"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="10">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG83114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="694" mass="76183" checksum="4DDB4E8E75A8CFC4" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWS4</accession>
    <name>A0A010ZWS4_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Flagellar biosynthetic protein FlhB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">flhB</name>
        <name evidence="13" type="ORF">SacsacDRAFT_0084</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the type III secretion exporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.85"/>
    <dbReference type="HOGENOM" id="CLU_041013_1_2_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006136">
        <property type="entry name" value="FlhB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00950">
        <property type="entry name" value="TYPE3IMSPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00328">
        <property type="entry name" value="flhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="11 12" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="5 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG83119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="362" mass="40727" checksum="F742654BF07B676F" modified="2014-06-11" version="1">MELRHKLDLQMFAGEKTEKATPKKRDESRKKGQVAKSQELPGSILLLTCIVMLMIFGGNFRTSITHMFTDVFNNRMTMEITVDNVMNMMMQYMLEILKLLAPIFIAVILIVILASFGQYGLLFVTEGLKPKFSKLDPIKGAKNLFSLRSIVELLKSLLKMSVIGFLVFTTLQGQMGVISILHSMSLEDILGFAASTTMSLGIKIGAALIILAVFDFMYQKFEFEKSIRMSKQDIKDEYKKAEGDPMIKGKIRERQRRMAMQRMMQDVPTADVIITNPTHYAVALKYDGDQMQAPEVVAKGQDFVALRIREIAKDNGVLIMENKPLARALFAQAEIGDTVPADLFQAVAEVLAYVYKLKGKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWS9</accession>
    <name>A0A010ZWS9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0089</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282355.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.90"/>
    <dbReference type="HOGENOM" id="CLU_000445_69_15_9"/>
    <dbReference type="OrthoDB" id="1630092at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="121" mass="13219" checksum="F83B91A51F1424FB" modified="2014-06-11" version="1">MANRILIVDDAAFMRMMIRDILTKNGFEVVGEAQDGSQAVEKFKELKPDLITMDITMPEMDGIAALKEIKKLDAAAKVIMCSAMGQQAMVIDAIQAGAKDFIVKPFQSDRVIEAINKTLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWT4</accession>
    <name>A0A010ZWT4_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flagellar basal body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">SacsacDRAFT_0094</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282368.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.95"/>
    <dbReference type="HOGENOM" id="CLU_013687_0_1_9"/>
    <dbReference type="OrthoDB" id="704242at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="3">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="4">
        <location>
            <begin position="187"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG83129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="276" mass="28448" checksum="E61CAB6A305270CD" modified="2014-06-11" version="1">MLRSMYSGVSGMKGFQTKLDVIGNNIANVNTTGFKSSRVMFKDILSQTSAGATAPTDERGGSNIKQIGLGVSIGSIDTLHLAGSAMTTNNPTDLRIDGDGFFAVSLGGDAAGGTFLTRAGDFHVDGAGNLVNSDGMFVLNTEGETITIDQGSSFSIGSNGIISIRDAEGAVTADNQLAVVVIRNPEGLEKAGGNLYRMGVNAMAGDDAGDGAVPLGADEGGNASRGAIVAGQLEMSNVDLTDQFTEMITAQRGFQANSRIITTSDEVLQEVVNLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWV8</accession>
    <name>A0A010ZWV8_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate--CoA ligase [ADP-forming] subunit beta</fullName>
            <ecNumber evidence="6">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Succinyl-CoA synthetase subunit beta</fullName>
            <shortName evidence="6">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sucC</name>
        <name evidence="9" type="ORF">SacsacDRAFT_0114</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="6"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282407.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.114"/>
    <dbReference type="HOGENOM" id="CLU_037430_0_2_9"/>
    <dbReference type="OrthoDB" id="316012at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="9"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding; shared with subunit alpha" evidence="6">
        <location>
            <begin position="321"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="53"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG83149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="385" mass="41353" checksum="7284BE4B239A7E2E" modified="2014-06-11" version="1">MNIHEYQGKEVLQQYGVTVPRGKVAFSAAEAVDAARELGTPIVVVKAQIHAGGRGKAGGVKVAKSLDEVRTYAEELIGKVLVTHQTGPEGKEIKRLLIEEGCDIKKEYYVGVVVDRGTGSVVLMASEEGGTEIEEVAAATPEKIFREVVDPAVGLQPFQARRLAYAINIPKELVNKAAKFMLALYEAFVDKDCSIAEINPLVVTGDGDVIALDAKLNFDSNSLFRHKDILALRDLDEEDEKEIAASKFDLSYIALDGNIGCMVNGAGLAMATMDIIKYYGGEPANFLDVGGGATKEKVTEAFKIILSDPEVKGIFINIFGGIMRCDVIADGVVEAAKQIKLEKPLVVRLEGTNVDLGKKILNESGLNIVSADSMADGAKRIVELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWX4</accession>
    <name>A0A010ZWX4_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fifty-four homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ffh</name>
        <name evidence="9" type="ORF">SacsacDRAFT_0129</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282438.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.129"/>
    <dbReference type="HOGENOM" id="CLU_009301_6_0_9"/>
    <dbReference type="OrthoDB" id="656414at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="8">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="108"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="190"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="248"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG83164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="458" mass="50687" checksum="709CAD0824AC727A" modified="2014-06-11" version="1">MAFEGLTTRLQNVFGKLRGKGKISEDDVNDAMREVRLALLEADVNFKVVKDFIAKVKEKALGKEVTESFTPGMVIIDIVNKELTELMGGTQSKLNKNNRPPTVIMMAGLQGAGKTTTTGKLAKMLQKQGSRPLLVAGDIYRPAAIKQLQVLGEQLSVPVFSLGDQVSPVEIARQGLQEAKDKGHDYVIIDTAGRLHIDEQLMEELKQIHTETKPDEVLLVVDAMTGQDAVNVAASFNEQLSLTGVVLTKLDGDTRGGAALSVKAVTGCPIKFISLGEKLDALEPFHPERMASRILGMGDMLSLIEKAQSGIDEKKAKEMERKMRNAEFTFDDFLEQMEQVKQLGPLDQIMDMIPGMNKMKQKSDLKVDDKQVGRIEAIVHSMTSAEKQSPDIINYSRRKRIATGSGTSLAEVNRLIKQFDEMKKMMKQLSGMMDPKGGKNKAMKQMQKMSKGMRFPFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWY7</accession>
    <name>A0A010ZWY7_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="4">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">SacsacDRAFT_0139</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the fabD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="4"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282462.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.140"/>
    <dbReference type="HOGENOM" id="CLU_030558_0_1_9"/>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="6">
        <location>
            <begin position="7"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000446-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="311" mass="31863" checksum="6D599E71E1F592B3" modified="2014-06-11" version="1">MGKIAFVFPGQGAQSVGMARDAYDALPDAKTLFDTADRTLGFGLTKLVFDGPVDDLKQTANTQPALLTASLALLQAVQAKGIEADYAAGHSLGEYSALAAAGVLSFEDAVTIVRARGLFMEAAVPGGQGAMAAVLGADRGKLAELCAEISAAGTVVEPANLNCPGQIVVSGSAEGVEALSARVKEIGAKRAIALEVSGPFHSSLMKEAAEKLGEKLADVTLGEGRIPVVANVTARPVSGAEAVRESLISQVYSPVLWEDSVQWLIGEGVDTFVEIGPGSVLAGLIKKIDKSVQVFSVNSLEAADSLAEALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWZ9</accession>
    <name>A0A010ZWZ9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA methyltransferase, RsmD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0149</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282480.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.150"/>
    <dbReference type="HOGENOM" id="CLU_075826_0_0_9"/>
    <dbReference type="OrthoDB" id="1827334at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="201" mass="22040" checksum="D715736502AB25FF" modified="2014-06-11" version="1">MRVVAGEAKGRPLKAVPGNGTRPTTDKVKEAIFSMIGPFFDGGVALDLFAGTGGLAIESLSRGAERAIFVDADAKSIEVVRANLKATGFEKQSEVYRNDAERALKVLAKRDTAFDLVFLDPPYRMKNGDELLLRMEESGLLQPGAVIVLEYESSYEYPEAFGSFSLRRKAVYGETAVSIYDWEPQNDAEEQEDSAEEDSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX32</accession>
    <name>A0A010ZX32_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506759.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138370_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019635">
        <property type="entry name" value="DUF2500"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10694">
        <property type="entry name" value="DUF2500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="151" mass="16903" checksum="1A63D3FB93FC46EE" modified="2014-06-11" version="1">MGWPDGEFRQDVNGNIVYETTSHEPGIMERISGFFDGAPLWFVIPFILIMGLITLTFVFGIGSVIIKSAKEKRSNEAAGILTVPARVFGKREEMRGGGESRVRTVYHLAFELENGERKEFQVEGEHYGVTAEGDSGMLTFMGTKFEKFERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX49</accession>
    <name>A0A010ZX49_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding domain-containing protein, AraC-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0189</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282542.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_3_9"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="191"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="304" mass="34870" checksum="88C51C51236200ED" modified="2014-06-11" version="1">MNRALLKEERIHGNPMYPVSSYVMEDLDYTTIMDSHWHEEMEFTIVTRGTVSFQIGTEYHEVRTGQAMFVHGGELHAGRRIGDEPCAFSAVVFDGEFLSSRGYDHLQEQFIEPLLQKKVRPPSHITGEEPWEREILNLIAAIIEDNERSVPAYQLTTKARLYQVFALLQGHMRENVPTATGGDLEKIERLKKVLGYMHKHYASPIKLVDLAELLGMSEGYFCRFFKSMVHKTPVDYLNRYRTQQACRLLETSGHKIVEIAMEVGFDNLSYFISVFKLHQGCTPSQYRKRLESAASSASGFVPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX97</accession>
    <name>A0A010ZX97_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase superfamily enzyme, subfamily IA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282586.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1376432_0_0_9"/>
    <dbReference type="OrthoDB" id="1669868at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="196" mass="21764" checksum="A15D5EF68DBD7859" modified="2014-06-11" version="1">MNLERAKPQLVFDVGGVLAENLDDFWSGMAQAGGIEKADLRARYKAEIGAALWRGSVTEENFWLWLGEACPAVKASEARALLDKVLLPLPALGLLKDWSERADIHILSNHVAGWILPLFAGIEDCLSSIVVSSEVGYEKPDPRLFAWAATKLKSSDVCFVDDKESNLEVARNLGWDTVLADPEGHWIQEIEHRLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXC6</accession>
    <name>A0A010ZXC6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone (Small heat shock protein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0249</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282640.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.262"/>
    <dbReference type="HOGENOM" id="CLU_046737_8_3_9"/>
    <dbReference type="OrthoDB" id="1523369at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="34"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="147" mass="17217" checksum="C0314CA4A06B409A" modified="2014-06-11" version="1">MFQQGPFGRHAEEIFDQMAKAFGGTFGEDFADKFRERALSFRTDIYEQDGRYYLEAELPGFDKEDIDIDYTASYLTIRAVRRDGKPQDDTRRIILSERRYGEFVRRFYLEDADREGIRALLKDGVLKLDIPKKDSPGSKRILIESEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXD4</accession>
    <name>A0A010ZXD4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fructose-2,6-bisphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282653.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_9_5_9"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="204" mass="23110" checksum="D58B02A8CF58D16B" modified="2014-06-11" version="1">MIELLVVRHGESQADLEDRHEGRADFELTPLGERQAGLAAAWIAKRYRPHEILASPLKRAARTAEAIAQECKLSVAYDEDLMEWNNGLLAGLKRDEARLRYPLPSTGRQPHDTFAEAESEIQFRARAEAFLSKLLFAQKNKSDLHRICIVSHGGMINMLFHSLTNLPFQSEISLATGDTGIHLWRIDGSRKRIVFMNAQEHLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXE5</accession>
    <name>A0A010ZXE5_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282680.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.286"/>
    <dbReference type="HOGENOM" id="CLU_133181_2_1_9"/>
    <dbReference type="OrthoDB" id="1938459at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021257">
        <property type="entry name" value="DUF2809"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10990">
        <property type="entry name" value="DUF2809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="154" mass="17632" checksum="59FAA3DCEE9A034E" modified="2014-06-11" version="1">MRSERKTRHRKRFGLRRRAVYLIAMTVVMLLGLASRAYSQTLPEFWADHAGDALWAAMVYLLFRLLLPDYRTWTCALGAVLFSFGIEFSQLYRAEWIDALRSTTLGALVLGRGFLAVDLLRYAAGIVACWVADISVLHLWSRKTDTNSSKEENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXF7</accession>
    <name>A0A010ZXF7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282705.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071055_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021239">
        <property type="entry name" value="DUF2625"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10946">
        <property type="entry name" value="DUF2625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="225" mass="25269" checksum="6180FC2FC2A0F1D0" modified="2014-06-11" version="1">MKALHELLSENSAWNPTEEAIKSAGNEVVVLERDRPQAEQTLVDLQMSDKATLGAVVLNTGGLLIDGGWLRVLGSGHPKIAGDIRSWNALGPDPIALKFKPEGYVIVAYDIAGGFFAVNNGAFNDHSPNIYYFAPDTLEWEDTEKGYTDFLHWALNGDLQQYYATFRWTGWEKDARMLNGGQAMMIYPFLWSEEGRDVNKTDRNPVPVAELWDLQQDMRKQLFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXG2</accession>
    <name>A0A010ZXG2_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.307"/>
    <dbReference type="HOGENOM" id="CLU_069356_28_0_9"/>
    <dbReference type="OrthoDB" id="1204683at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="196" mass="21683" checksum="610CCD337B5DFD56" modified="2014-06-11" version="1">MRPRAFDEEQALDAAMRVFWEKGYEATSLSELTEKMNIRKPSLYAAFGDKRELFSRSLDRYTAKHLAYIKRVLERENAVIPAFRSLLYDLAEGGSAGDPALGCLAVLTLDELAPQEAAWTEKAWAHQLRLAELFRSKIDEGLQSGELAQGQDAEALGNALLASVIGLTVMLKTLPNPTFIESTISATLTLFEEAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0L4</accession>
    <name>A0A011A0L4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">SacsacDRAFT_0002</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282148.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.2"/>
    <dbReference type="HOGENOM" id="CLU_031275_8_2_9"/>
    <dbReference type="OrthoDB" id="944044at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="369" mass="41547" checksum="0A474B17A1B20EBC" modified="2014-06-11" version="1">MFKSDRFMRTSLHIIFVLIILFLLTQIPSILAPLKAAFSLIFFPIAMSLFLYYLFRPTIRKLHDWHIKRPWSILMLYAAAVGVFAGFAIWVWPILRSQFLNFSDNLPQLAQNFSTQLQLLMLKVQEQEIWGTRINDIDVGIDIPQQLSGYLENVLNSISNSLTSALSTVAWIFLVVSTVPMILYFMLKDDRKGYAFLLKAAPMKIRPTFRDMAKDIDSALSGFIVGRVLLAACVGVFDLIGFLIVGVPYPLLLVLFIILTDMIPYIGVYLGAIPVVIVGFIDSPTSVIWIIVVIVLGQMLRNNLLSPMIYGSALDIHPLTTVFLLLSGGAIGGFIAILIIIPSYMVVKIVAVHLYRYYRSSKLTRPDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0M3</accession>
    <name>A0A011A0M3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3296083_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="40" mass="4604" checksum="AE1A32CAF8C495A4" modified="2014-06-11" version="1">MSTFKESFAVRPQEVYRPLRALSQLHIDEASVRCLPARNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0N3</accession>
    <name>A0A011A0N3_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Nicotinate phosphoribosyltransferase</fullName>
            <ecNumber evidence="4 8">6.3.4.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">SacsacDRAFT_0022</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the NAPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="4 8"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282187.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.22"/>
    <dbReference type="HOGENOM" id="CLU_025154_2_1_9"/>
    <dbReference type="OrthoDB" id="241792at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041525">
        <property type="entry name" value="N/Namide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041619">
        <property type="entry name" value="NAPRTase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040727">
        <property type="entry name" value="NAPRTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007229">
        <property type="entry name" value="Nic_PRibTrfase-Fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006405">
        <property type="entry name" value="Nic_PRibTrfase_pncB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098">
        <property type="entry name" value="PTHR11098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04095">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17956">
        <property type="entry name" value="NAPRTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17767">
        <property type="entry name" value="NAPRTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000484">
        <property type="entry name" value="NAPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01513">
        <property type="entry name" value="NAPRTase_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7 8" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NAPRTase_N" evidence="10">
        <location>
            <begin position="8"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="NAPRTase" evidence="9">
        <location>
            <begin position="154"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="NAPRTase_C" evidence="11">
        <location>
            <begin position="360"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG83057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="488" mass="55733" checksum="A6D00AE57C185CED" modified="2014-06-11" version="1">METPGMALHTDKYQINMMYAHWMHGTHKHRAVFEAYFRSLPFGNGYGVFAGLERIVHYISNLRFQEDDIRYLSEQEENYDPLFLEELRTFHFNGTVHSMREGAVVFPNEPLIRVEGTIFEAQLVETALLNFMNFQTLIATKAARIKQAADGDTLLEFGTRRAQEADAAVWGARAAYLSGFDATSNMMAGKRFGIPTKGTHAHAWVQSFGSEQEAFDKYAEVLPDYSSLLVDTFDTLRSGVPNAIRTAKKLEERGKRLNSIRLDSGDLAYLSIEARKMLDEAGLDYVKIVASNDLDEHTITELKTQDARIDIWGVGTQLITAHDQPSLGGVYKLVEREVDGIMQPTIKISANPEKVTTPGKKDVYRIIDRGTGKAIADYICFPEEDEPSEGKQLKLFNPLHTYIRRYVKNYDAERMLVPIFEEGKLVYELPSLNDIRDYHASQLKQFWPQYLRKLNPEIYRVNISEKAWQLKQGLIDRYMEETEGTPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0Q5</accession>
    <name>A0A011A0Q5_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="4">dUTPase</shortName>
            <ecNumber evidence="4">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dut</name>
        <name evidence="6" type="ORF">SacsacDRAFT_0047</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="4"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.47"/>
    <dbReference type="HOGENOM" id="CLU_068508_1_2_9"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00116">
        <property type="entry name" value="dUTPase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="68"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="85"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG83082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="148" mass="15965" checksum="DFE10F80408AE17F" modified="2014-06-11" version="1">MSHLVQIKRFPGNEDLALPRKMTELAAGYDLQAAVLEPMVLAPMQRALVPTGIAIAMPGGLEAQIRPRSGLAFKHGITCLNSPGTIDADYRGEIKVLLINLGQEPFTIARGERIAQMVFQEIPETALTEVEELSETVRGTGGFGHTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0R0</accession>
    <name>A0A011A0R0_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="4">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="4">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truB</name>
        <name evidence="7" type="ORF">SacsacDRAFT_0052</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="4"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282264.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.52"/>
    <dbReference type="HOGENOM" id="CLU_032087_0_1_9"/>
    <dbReference type="OrthoDB" id="1166299at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="5">
        <location>
            <begin position="26"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="6">
        <location>
            <begin position="178"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="304" mass="33764" checksum="E26D4E23A691612D" modified="2014-06-11" version="1">MNDFDGVLPVHKPAGMTSHDVVAKCRRLLQMKRIGHTGTLDPSVTGVLPLCLGRATRMVEYLQEMPKEYRAVLKFGIATDTEDLTGTIIEELPETGITEAQVREALADFIGPIMQTPPMYSAIKVDGKRLYELAREGKTVERKAREVVIHELEVTGFEEGDQPEVSLRVLCSKGTYIRTLCVDLGAKLGVPSTMAKLERTLSAGIGLDGCLTFEEIAERMEAGTLADTLVRADKAAVHMPEHKVDERRLENALRGQKLSSWAVLPSAEGLQKEFRLYTPDDRFIGIYRWDEEVGKVVPVKVFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0R5</accession>
    <name>A0A011A0R5_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleic-acid-binding protein implicated in transcription termination</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282275.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.57"/>
    <dbReference type="HOGENOM" id="CLU_147970_2_1_9"/>
    <dbReference type="OrthoDB" id="2067975at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00279">
        <property type="entry name" value="YlxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007393">
        <property type="entry name" value="DUF448"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037465">
        <property type="entry name" value="YlxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035931">
        <property type="entry name" value="YlxR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34215">
        <property type="entry name" value="PTHR34215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04296">
        <property type="entry name" value="YlxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64376">
        <property type="entry name" value="SSF64376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YlxR" evidence="1">
        <location>
            <begin position="9"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="103" mass="11997" checksum="EE0DF05ECC4B8BBF" modified="2014-06-11" version="1">MKTKKVPLRKCVASQEMLPKKELIRVVRTPEGQIEIDLTGKKSGRGAYLRADADCFRLAQKNKSLDRALKQPVPAEIYEQLARDFIRVEHQFRELQERETDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0S8</accession>
    <name>A0A011A0S8_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282318.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169649_0_0_9"/>
    <dbReference type="OrthoDB" id="2075911at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="105" mass="11530" checksum="EC247959C7BC98A0" modified="2014-06-11" version="1">MKAIEVQLSVHRAPETSRMQQEQLQRPLIDQAQLAGQATAEIERSRHRSAPTTEAADAQIRKDAEGNNQHDSHGGGAHEQDQPEAEARTVAAPHPFKGKHLDLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0T4</accession>
    <name>A0A011A0T4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheC, inhibitor of MCP methylation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282329.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.78"/>
    <dbReference type="HOGENOM" id="CLU_087860_2_0_9"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007597">
        <property type="entry name" value="CheC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04509">
        <property type="entry name" value="CheC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheC" evidence="2">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="CheC" evidence="2">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="208" mass="22162" checksum="DD9557F1473C300D" modified="2014-06-11" version="1">MEIFSKLEGFKLDVLKEVGNIGAGHAATALSQLLNKPIDMAVPKVQILPFEDIAEKVGGAEKIVLTVFFRVEGDAPGNLFYIMGPEAGKSLLQRLGAFEPTEGLELTEMEQSALGEIGNILAGSYLSSLADFTNLAMSPTVPALALDMAGAILSYGMIQFGEMGDAALLIDTTFVQGNDEVEGQFFLIPDPESFDKIFTALGVPLDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0T8</accession>
    <name>A0A011A0T8_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flagellar biosynthesis protein FlhF</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Flagella-associated GTP-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">SacsacDRAFT_0082</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282341.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.83"/>
    <dbReference type="HOGENOM" id="CLU_009301_11_4_9"/>
    <dbReference type="OrthoDB" id="1162441at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020006">
        <property type="entry name" value="FlhF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF3">
        <property type="entry name" value="PTHR43134:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03499">
        <property type="entry name" value="FlhF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="277"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54" evidence="12">
        <location>
            <begin position="278"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG83117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="473" mass="52621" checksum="3F0B673A6ACD9B62" modified="2014-06-11" version="1">MIVKRYVVETMIEAMQKIRTDLGSDAVILSTKETKVGGVFGLFGKKRLEVVAALESDKKETEPARPKAAAAPLPVPAAIPRSVGAGAYRKASNVANPQKPEAESVESSPLNGKNVAVSSFNQGLEDLRIKPEAQSSDNLSSGSVLAAVPSKTPMIQEEPDLTLQAEQQRQLERSIREFQQDGIPAREDRLYEELHQMRLIIDKLSRNHDESDPMPENLDKLLVQLREQHVDEALIQDWLERIRAKEGPAFSNSSAEEFRQEIRAFTENREGGGIGDDTRIVYIAGPTGVGKTTTIAKLAAEQMFKKKRKVGFITSDTYRISAIEQLRTYASILNVPLEVVQSPGDLQRAFQKLESCDLILMDTAGRNYRNEMLVSELQALIAPAEYSETYLVLSLTSKYKDMAEITDNFNQYKLDKVIFTKADETGSFGSIFSLLYRYPLKYSYITNGQNVPDDLLLPSGNLLVDVLLGEQTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0U2</accession>
    <name>A0A011A0U2_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Flagellar biosynthetic protein FliP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">fliP</name>
        <name evidence="14" type="ORF">SacsacDRAFT_0087</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays a role in the flagellum-specific transport system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the FliP/MopC/SpaP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282351.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.88"/>
    <dbReference type="HOGENOM" id="CLU_042028_0_1_9"/>
    <dbReference type="OrthoDB" id="1049349at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005837">
        <property type="entry name" value="FliP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005838">
        <property type="entry name" value="T3SS_IM_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587">
        <property type="entry name" value="PTHR30587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587:SF0">
        <property type="entry name" value="PTHR30587:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00813">
        <property type="entry name" value="FliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00951">
        <property type="entry name" value="FLGBIOSNFLIP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01302">
        <property type="entry name" value="TYPE3IMPPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01103">
        <property type="entry name" value="fliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01061">
        <property type="entry name" value="FLIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7 12" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="11 12" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="5 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="14" id="KW-0969">Cilium</keyword>
    <keyword evidence="14" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458471" description="Flagellar biosynthetic protein FliP" evidence="13">
        <location>
            <begin position="27"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="55"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG83122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="257" mass="28236" checksum="43FCF9AD78283B82" modified="2014-06-11" version="1">MKKKLTITFALLIAALFIQVLPTAHATGTENPIPNIDLQIGGDSDGTPATSTLSVLLMITVISIAPAVLVLMTSFTRIVIVLSFVRTSLGTQQMPPNQVLVGLALFLTLFIMSPTLSSINDTALQPYIRGELTQMEALDQASVPMKEFMFKHTREKDLLLFMDYTGAEKPESFQDIPLTVMVPAYAISEMKTAFQMGFMIYIPFLVIDIVVSSTLMAMGMMMLPPTVISLPFKILLFVLVDGWYLVVKSLLLSFDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0U8</accession>
    <name>A0A011A0U8_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Flagellar protein FliL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">SacsacDRAFT_0092</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Controls the rotational direction of flagella during chemotaxis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the FliL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282361.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099018_8_0_9"/>
    <dbReference type="OrthoDB" id="1817935at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005503">
        <property type="entry name" value="FliL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03748">
        <property type="entry name" value="FliL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG83127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="154" mass="16809" checksum="9BB05CFACB0F3AF6" modified="2014-06-11" version="1">MKKLLPWIITMFLAITLIVVAVFLVLGNNKDTANAAGEKEEVKQEKHLTAKEIVAVSSDITGIKTNLSDPSFIVQIDFSVQLSDAKVKAEFDEIKEITIKPIILMTLADTTPEALSTAKGKTQLNTKLKNLINKAMPEGEVVSVNITNFILATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0W3</accession>
    <name>A0A011A0W3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0107</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3391201_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="32" mass="3617" checksum="89E5E366EFA1E364" modified="2014-06-11" version="1">MGVFPIRGAKKASTKFSEELQKNNSLVEFNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0Y7</accession>
    <name>A0A011A0Y7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Channel protein, hemolysin III family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">SacsacDRAFT_0132</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0073 (Hly-III) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282448.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.133"/>
    <dbReference type="HOGENOM" id="CLU_051078_1_0_9"/>
    <dbReference type="OrthoDB" id="1659567at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005744">
        <property type="entry name" value="Hy-lIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="PTHR20855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01065">
        <property type="entry name" value="hlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="213" mass="23793" checksum="1B22AE6309F186BC" modified="2014-06-11" version="1">MANTHTYSRREEVANAVTHGIGAALSVAALVLLIVFASLKGNAWHVVSFTVYGVTMLLLYMSSTLVHSFREGKVKDFFEFMDHSSIYLYIAGTYTPFMLTAIRGPLGWTLFGIVWAIAIGGVAFKAFFVKKFLFMSTLFYILMGWLIVLAWGALTQAIPAEGIHLLVAGGLMYTVGTIFYVWRGFPHHHAVWHLFVLAGSILHFFCILMYLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A107</accession>
    <name>A0A011A107_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.153"/>
    <dbReference type="HOGENOM" id="CLU_000445_88_6_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="189"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="290" mass="32865" checksum="FBF4594C812CB4DE" modified="2014-06-11" version="1">MYKKKEIFDSEGDTAMHSAHRRYFTEFKDQPLPLYMESVGYNPDQEAFVRPNGYNCYHWLQTVGGKGEFTMGGAKYVMEGGSGILLLPGEAHEYRPLEGKWQTYYMTFGGAQAGGILGTLGLPVSSYYGWDEAAELGGFVPGLLNRMSNERDISGLSVSVEVYRFLTLLKKDGRVNRLPSLSNSVRRLTPVLEFLDRYYADADIGLEDMAHRADITPRHLNTLFKQAFGMTAYAYLILLRLRKAKEMMTLHPRMTVKEVSGLVGFRDASHFVATFRKQEGVTPEQFRLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A121</accession>
    <name>A0A011A121_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cobalamin binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.169"/>
    <dbReference type="HOGENOM" id="CLU_064060_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="1">
        <location>
            <begin position="226"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="375" mass="42539" checksum="0D9BB50FF52E237D" modified="2014-06-11" version="1">MTIREEQLLLADIDGLAARVTKEHYDIQPDLFERYGKPGFEKSRRDTVYTLHYLAESVRMDSPSLFVHYIGWLKQLLSGYGLTDADIRLKLEIVLRCIREARRDEWTDRTVRILEMGILRTSEPAETPSFIVEKHRLGREVRTYLDALLRSDRLEAYALIDRLIERGESVRDVYQYVFQVSQYEVGLLWQTQQISVADEHYCTAITQSAMSRLYQRWIGDERPSRGGVLVSACVGGELHEIGLRMLTDVFEMEGWDTHYLGANTDEDQLLDEVLHRGADIVALSATMTFHVHIMKKLIGALRADERSAKSMILVGGLPFNVDPSLWKRIGADGYAPDAEKALAEADRLLAARARGAEREANLQEAASEGGHELGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A131</accession>
    <name>A0A011A131_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyl esterase (Deacetylase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282523.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.179"/>
    <dbReference type="HOGENOM" id="CLU_054209_1_0_9"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008391">
        <property type="entry name" value="AXE1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039069">
        <property type="entry name" value="CE7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40111">
        <property type="entry name" value="PTHR40111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05448">
        <property type="entry name" value="AXE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AXE1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="319" mass="35386" checksum="26920EE8FD09BD10" modified="2014-06-11" version="1">MTHAIKARIQDLERYNPSQTAESDLEEFWSNTLAEYAEKPLNGKREPVQTPMSGMDVYMTTYEGADDTPLHAWYLTPKAEQGTKFPCIVHYHGYTGSKGMPEHFAHYILMGFAVLSVDVRGQGGDTGNRQAQSYGAIRGWVTPGILQRETAYYRAITVDAIRAAEWAAEQPETDAERIFVIGGSQGGGLAMIVPALSDVPKAAVAHIPNMCHMDFGILNSNSSLSEAAEFVSRHPEHLDTVLKTLSYFDNLNLAPRIQIPIMVSCGLKDPCCMPETVYAAYNRIMSEKEMRVYPFDGHWVSDGQNRLAMEFLARQAGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A135</accession>
    <name>A0A011A135_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0182</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.184"/>
    <dbReference type="HOGENOM" id="CLU_039610_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="2">
        <location>
            <begin position="229"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="412" mass="45674" checksum="6662344DDA656528" modified="2014-06-11" version="1">MTKSKRIHLIDGLRGFSLSGIIVANMLIFQYGLFGETMPELFGIAGADLAFHSFLFIAVVGSFMPIFAFMFGFGMVKLSDSLKSRELRPKCHLARRFLLLFVFGLLHSLFLWEGDILTFYGATGFFLLLFLNRKPKTLLVWATLLLGIMGILGAFPSDADMTEFGDSEHTRTYVMQSRDVYGSGTYEEIKDFRNNADPFGMGETWIMAFAVLLAPLMIAPMFLLGMRAAKVGTFDDPVAMRRTYARRAAVFVSVGLLTKSFSVLAPQFGASGLPGVGIGDTLGGSLLALGYIYAFALLYASRRRFAILKRFEAVGRLSLTNYLMQSVICTTIFYGYGLGLFGRAGVAVGTLIVLAVYAAQLWLSPLYLNKFRNGPVEKALRVWTYLSRKGQPRKPVRVEAPENAELSERIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A146</accession>
    <name>A0A011A146_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282546.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.197"/>
    <dbReference type="HOGENOM" id="CLU_078234_0_0_9"/>
    <dbReference type="OrthoDB" id="1459765at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018728">
        <property type="entry name" value="DUF2268"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10026">
        <property type="entry name" value="DUF2268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2268" evidence="1">
        <location>
            <begin position="86"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="309" mass="34498" checksum="6199F1E5BF06BEB4" modified="2014-06-11" version="1">MKITTLRSDKVYRRIMQLPQEEKREAYREQMLAPFQGKWEIQQIPFRADSPGGFDVLTLNDLMYLPANEIDESALAQVNEISSDAFWAACEKVVSDSFSSFGQQGIALPVQKVVFTVLLGNPDSELLRINQGYSGDGGIPGYILTVLTPNAYTLPRITAALAHECNHNVRYQFIKWDMNVTLAELIVSEGLAENFAVSRCGEKWLGPWVSKTDTQTLNRVIKPMLKPALNLQGWHNIAPRLYGDEIAALQGMSPAGLPYGAGYACGYHLIRHYLRKTGESIEQATLKSADEILKVTEDYWHAESVVDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A151</accession>
    <name>A0A011A151_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative anaerobic dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">SacsacDRAFT_0197</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282556.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.204"/>
    <dbReference type="HOGENOM" id="CLU_000422_13_4_9"/>
    <dbReference type="OrthoDB" id="323168at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00490">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="6">
        <location>
            <begin position="15"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="712" mass="77063" checksum="8C309373B5EB5640" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A156</accession>
    <name>A0A011A156_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282570.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.209"/>
    <dbReference type="HOGENOM" id="CLU_153135_0_0_9"/>
    <dbReference type="OrthoDB" id="1736266at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="105" mass="12355" checksum="AD310325C2071FC1" modified="2014-06-11" version="1">MAFGINRQELSRWKASVERGEIAYLTHFWLDPRFPGITSVTKVGCSDLDRLACWCLDNGLSPNHIHRRDRYPHFDLIGSKQAEILRREGLLDQLHRFVERKNHNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A177</accession>
    <name>A0A011A177_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EDD domain protein, DegV family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282601.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.233"/>
    <dbReference type="HOGENOM" id="CLU_048251_3_2_9"/>
    <dbReference type="OrthoDB" id="1288126at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="280" mass="30194" checksum="E7E09B48FADB31BE" modified="2014-06-11" version="1">MRKIKVVTDSTVDLSGAVLEEHGVEMVPLSFTIDGQMYTDRVDITPETFIQKMIHANELPKSSQPAVGAFVELYDRLGAEGYDVLSIHMTGGMSGTVRSAAMAADMTDTNVTVVDSKYITRALGFQVLEAAQMAAEGRSMDEIVARLDEIRAATRLYVVVDTLENLVKGGRIGRGKALIGSLLHIKPIGTLNDGVYTPVMNARSHAQVVKHLAKQFADDVKGSTVKGVGLVHAEGCKLAENLKEKIAELTGYSNIEIDYTGPVISTHTGPGAIGFTYYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A179</accession>
    <name>A0A011A179_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Glutaminase</fullName>
            <ecNumber evidence="3 5">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glsA</name>
        <name evidence="6" type="ORF">SacsacDRAFT_0227</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glutaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="3 5"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282611.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.238"/>
    <dbReference type="HOGENOM" id="CLU_027932_1_0_9"/>
    <dbReference type="OrthoDB" id="1288854at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00313">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015868">
        <property type="entry name" value="Glutaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12544">
        <property type="entry name" value="PTHR12544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04960">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03814">
        <property type="entry name" value="Gln_ase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG83262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="315" mass="33924" checksum="CD7E3EAE62702CE2" modified="2014-06-11" version="1">MTNKEARLEEVRQFLPQWLEESRKEAASGEVASYIPELSKASHTALGIHLLDIQGDSASAGDCGMSFTLQSISKVFTLILALIDNGEDAVFERVGMEPTGDNFNSMLKLELVRPGIPFNPLINAGAITISSMIKGATPEEKSARILDFFRRLSGGSPLKVNEAVYRSEFETGNLNRSIAYFLVENGVLNGSVEEVLSIYFRHCSIEATCRDLARMALILAGDGTDPLSGENLIPRRYVQIAKTFMITCGMYNASGEFAIKAGLPAKSGVSGGILTFVPGALGIGVVGPALNAKGNSSAGVHLIERLSQRMDWSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A190</accession>
    <name>A0A011A190_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282631.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.254"/>
    <dbReference type="HOGENOM" id="CLU_074761_0_1_9"/>
    <dbReference type="OrthoDB" id="1355703at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011152">
        <property type="entry name" value="Pesterase_MJ0912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000883">
        <property type="entry name" value="Pesterase_MJ0912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="3"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="243" mass="27663" checksum="0B3C84CB51BCDD12" modified="2014-06-11" version="1">MSKFAIISDIHGNLPALEAVLDDIGSRGITEIYCLGDLVGKGPSSDLAVDLIRRHCRHVVRGNWDEFLPQPTEFPTLLWHQKLLGEERMAYLRSLPFSIEFRLSGRYVRLFHASPRSVYERVQPWDDYERKVSLFESSDLSAEPVKADVAGYGDIHNAYMQHMEGRMLFNAGSVGNPLDMTQASYAILEGDPGETRKTRLDLTFARVPYDIERAVRQAQEANMPDLEPYVREITTGRYRGLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A1B5</accession>
    <name>A0A011A1B5_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type multidrug transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">SacsacDRAFT_0278</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282691.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.295"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_9"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG83312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="308" mass="33969" checksum="4AB6D74169768299" modified="2014-06-11" version="1">MPDTIIEMKNLTKAYGSKIAVKNMDLSIYRGEIVGLIGKNGAGKSTLLKMVAGLVHPTSGELHFFNRASADGQSFFERMGVLIEQAGLYPHYSAFENLKLLAIAYGLPDANAQIARLLKTVGLESSGSAKVKSFSLGMKQRLGIAAALLGSPDVLLLDEPINGLDPQGIVEIRALIRELNKDGLTILISSHILEELSKIATKYVIIHQGEMVEVISADDLLHKCEERIELRLEAIEAAIPVLERELKITDYKVSDNNTVYVYEKGAQIRQISKTLIEHGIEIDSIHKHQQSLEQYFLARTEQAGERHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A1C7</accession>
    <name>A0A011A1C7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282723.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083624_1_0_9"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="34"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="269" mass="30572" checksum="26C6023E11321329" modified="2014-06-11" version="1">MTEQNWSKIGDGGTAEIFADEHGRVVKLFREWFRKESADYEYRKSVWAYEQGLPTAEPLGRTQYDGREAILLKKIEGESLLQRLQREPQTAAEAAKTFAAYQARLNSLEAATIGDSQRERLVQRLSRVEQLNETERAAVRSQLEQLPDDERLCHGDFHPGNIMESEQGWQVIDWIDANCGHPLYDVARTLLLLGFGTEAGGPRGSMEEAAEVFREAYLQTYIELTGFEESDVKRWMLPVAAIRLIEPIPEPEKEKLLRFIRDALSGGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM46</accession>
    <name>A0A011AM46_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2221328_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="106" mass="11974" checksum="553A18BEED06CB6F" modified="2014-06-11" version="1">MFLKRNCLCGSCFQTFECTGAFSPDSDRYIKGAVAWMKIVAREPGRLLMEGHTLCTYCSNPHQFLVEYDCVKDQYNEASDLSPSQPFIPRSSERTQSGRPSPSFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM49</accession>
    <name>A0A011AM49_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282166.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163967_2_1_9"/>
    <dbReference type="OrthoDB" id="1891602at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008326">
        <property type="entry name" value="UCP034852"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034852">
        <property type="entry name" value="UCP034852"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="97" mass="11235" checksum="02D196419962D835" modified="2014-06-11" version="1">MSLNVTQQAADWYKKELGLQSGDYIRFYARYSNTSDIHPGFSLGIATEMPSSPGLTQSSEGITFYMEEKDLWYLDGYRLNVTYLPEHDDILYAYEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM56</accession>
    <name>A0A011AM56_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">SacsacDRAFT_0021</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282184.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.21"/>
    <dbReference type="HOGENOM" id="CLU_060916_0_0_9"/>
    <dbReference type="OrthoDB" id="1619561at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016625">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011894">
        <property type="entry name" value="PorC_KorC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02175">
        <property type="entry name" value="PorC_KorC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="245"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="283"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG83056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="332" mass="35910" checksum="6CA9AF33993E0A8F" modified="2014-06-11" version="1">MAVLPEVNKLGFFEIRLESIGGLGANLAGKMLAEAGIVGAGMDGVSFSSYGSEKKGSPVKAHIRFCELGTPIRDTSPIEHPHVIGIFHEALIRTGGASGVRPGGIVLVNSAHSAQRIADDAKLHGCTVAVLDATRIALEEKNKVNMAMLGGLFRLCGFLDPEFMKDVIAKSLGKKYPQAVELAIRVFERGYSEIEMLEVPAKAGDEVYEKAPENPFGYLNQPLGGMVVTPGSSLLKDLSISRSGMLPAFDQATCINCAQCDTACPDLCFVWEEQPDKRGRMQMVLQGIDYQYCKGCLKCVEACPTDSLSRMLEQEGYADANQVKHRFDFVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM60</accession>
    <name>A0A011AM60_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282194.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.26"/>
    <dbReference type="HOGENOM" id="CLU_141458_1_0_9"/>
    <dbReference type="OrthoDB" id="2003042at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010368">
        <property type="entry name" value="Com_YlbF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023378">
        <property type="entry name" value="YheA/YmcA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06133">
        <property type="entry name" value="Com_YlbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158622">
        <property type="entry name" value="SSF158622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="148" mass="16413" checksum="118DA43AA4B6F04E" modified="2014-06-11" version="1">MDIQQNKDSEKMSVGAPVGVWNRSDIVNKTRELAGLISSSEEVRIFQQAERQIQGHERIQYLITTIKKKQKEIVAFEAMKNAKMAAMIEAELSELQDELDGIPIVSDYQEGQVEINDLLQMVISAIHTTVSEKIVVEKGADAPPASCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM95</accession>
    <name>A0A011AM95_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">frr</name>
        <name evidence="5" type="ORF">SacsacDRAFT_0066</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282299.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.66"/>
    <dbReference type="HOGENOM" id="CLU_073981_2_0_9"/>
    <dbReference type="OrthoDB" id="1674344at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="4">
        <location>
            <begin position="20"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG83101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="184" mass="20707" checksum="C2BB899975E41F42" modified="2014-06-11" version="1">MPQTVKKNAEDRMGKAIQALQRDLSTLRAGRAVPALLDRIQVEYYGAPTPLNQLANINTPDSRTLMIQPWDKSSLGEIERAIQKSDLGLTPSNDGNAIRLVIPALTEERRTELVKLTKKFGEEGKVAVRNIRRDANDDIKKMEKGEISEDESRGHQEEIQKLTDKYIAEVDKVIAAKEKEIMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMD2</accession>
    <name>A0A011AMD2_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flagellar biosynthesis/type III secretory pathway protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0101</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282379.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.102"/>
    <dbReference type="HOGENOM" id="CLU_062625_1_0_9"/>
    <dbReference type="OrthoDB" id="1285795at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018035">
        <property type="entry name" value="Flagellar_FliH/T3SS_HrpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02108">
        <property type="entry name" value="FliH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FliH" evidence="3">
        <location>
            <begin position="129"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="273" mass="31042" checksum="61B29FF15E369749" modified="2014-06-11" version="1">MSNLIKSSQYVPKEDFVKLDLHRHYASQQPHADEDEKSPLPVADQQTIILKDEMIRDAKEFAELQIRDAAQQAEQMLADAQQQIEMWWQERREQDEHLVEAVKTQAFREGYEEGKAQAEAELAVRMQEASEEAQALIQEAIQTKEAIIQESEPFLVELSSAIAEKVIDRKLAEDEELTLNLIRQTLSRKREQGTITLCVAPSQFSLINSAREELAMSIDSQAELQILPDSTVKDRGCVIRSNFGSVDARIDTQLVEIKRELLRLALHDESTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMD8</accession>
    <name>A0A011AMD8_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Flagellar basal body rod protein FlgB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">SacsacDRAFT_0106</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282391.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.107"/>
    <dbReference type="HOGENOM" id="CLU_125463_3_1_9"/>
    <dbReference type="OrthoDB" id="1914857at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006300">
        <property type="entry name" value="FlgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30435:SF12">
        <property type="entry name" value="PTHR30435:SF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002889">
        <property type="entry name" value="Rod_FlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01396">
        <property type="entry name" value="FlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="6">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="135" mass="14847" checksum="66A93758D8A8FC37" modified="2014-06-11" version="1">MNILNDTGFNRLRSAIDASNTRQQVISNNIANADTPYFKRSEVSFESLLQSEMNGVSSIKGRITNSRHIAIGSAGSIPTAKVTSDDSTAMNNNKNNVDVDTEMTSLAENQLRYNTYIEEVNHQIKMMRTAMGGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AME7</accession>
    <name>A0A011AME7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mg chelatase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282412.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.116"/>
    <dbReference type="HOGENOM" id="CLU_026145_1_0_9"/>
    <dbReference type="OrthoDB" id="581802at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032508">
        <property type="term" value="P:DNA duplex unwinding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="226"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="524" mass="56957" checksum="B0B3CC44A9961ADE" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMI0</accession>
    <name>A0A011AMI0_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Met) cytidine acetate ligase</fullName>
            <ecNumber evidence="1">6.3.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tmcAL</name>
        <name evidence="2" type="ORF">SacsacDRAFT_0146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetate + ATP + cytidine(34) in elongator tRNA(Met) = AMP + diphosphate + N(4)-acetylcytidine(34) in elongator tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:58144"/>
            <dbReference type="Rhea" id="RHEA-COMP:10693"/>
            <dbReference type="Rhea" id="RHEA-COMP:10694"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TmcAL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.-" evidence="1"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506754.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.146"/>
    <dbReference type="HOGENOM" id="CLU_038915_0_2_9"/>
    <dbReference type="OrthoDB" id="1547014at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01539">
        <property type="entry name" value="TmcAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008513">
        <property type="entry name" value="tRNA(Met)_cyd_acetate_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37825">
        <property type="entry name" value="PTHR37825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05636">
        <property type="entry name" value="HIGH_NTase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="426" mass="44899" checksum="493EC3F7476E4CD0" modified="2014-06-11" version="1">MKTVGLIVEYNPFHNGHRLHLQRSLQTAGAEASIAVMSGPFTQRGEPALLSKRARTEMALAAGVDLVIELPVLYALQPAEWFAFGAVSLLDATGVADSICFGSESGEVAPLEELAARMQGGESPVMQAALKQALAEGLSFPAAYAKAASEQGGGGSQAASLLGNPNDTLGLHYVLALRRLASTMAPLAVRREQAGYHDAGLPAGGQIASATAVRAALARGTGGLDEAAPYLPAGSLRVLRREAEAGRILTAGWEALAQPLLAALITRAPEELALVPEVSEGLEHRIAAALPRLPVPGVEALLAAIKTKRYTRTRLQRLLAHALLNHGGPLFGRDSLAQGPQYIRVLGFSPKGRALLKTMKKTAKLPIVVRAADFDHPQLQLDIRASAVHASAFPSPQIKEMYADYYAPPIILGDSDSDEPPKGDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMI5</accession>
    <name>A0A011AMI5_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysophospholipase L1-like esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282482.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.152"/>
    <dbReference type="HOGENOM" id="CLU_051989_5_2_9"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008265">
        <property type="entry name" value="Lipase_GDSL_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01098">
        <property type="entry name" value="LIPASE_GDSL_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="11"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="217" mass="24133" checksum="BC78A7DEF8832E82" modified="2014-06-11" version="1">MKLNTHDKLLLIGDSVTDAGRAYPVGYGNGLGNGYAALVDALLRTGYPELNTLVLNTGVGGNTVRDLKSRWQTDVLDLKPDWLSIMIGINDVWRQFDTPEAVHSFITLEEYEATLRELLDAVQPGLKGLILMTPYYMTGQEDPMRSMMDRYGAVIKRLAGDYGAELVDTQAAFDRMGHHVIQSSLSNGWDHVHPNTAGSMVLARALLHALDFEWERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMJ1</accession>
    <name>A0A011AMJ1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter, MnhD subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0156</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282492.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_930312_0_0_9"/>
    <dbReference type="OrthoDB" id="1925511at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="7">
        <location>
            <begin position="92"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="299" mass="32287" checksum="00E57985CB1A07BB" modified="2014-06-11" version="1">MDGRRGNDGNEGSRNSAGQKEGGLFGRDESQNRNSQPGAQSAYGQGSYYEESNEEDLYGRQPDDSYDGSRQEQRGGQPEEDRSLGGLSPWLRVWIHPRQVTRDFMRSSDPLRGALLLALIAGVFNALNTASTRNSGDTMTASGLAVSVLLGGVIGGLATYYIGAWLMKLVGGWLGGVGSTQDMRIVSGRISGMLAIMVGLFWIPELLIAGMENFTYSTPNLDASMLRTLLYLLFVLLESGFGIWSFVAVLHAAGEAHRFSAWKALLMFVILGVCVFFLAFIVILVVALMFGAAFGAFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMK5</accession>
    <name>A0A011AMK5_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative metal-dependent hydrolase SacsacDRAFT_0171</fullName>
            <ecNumber evidence="5">3.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0171</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Possible metal-dependent hydrolase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the metal hydrolase YfiT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.-.-.-" evidence="5"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.173"/>
    <dbReference type="HOGENOM" id="CLU_105789_1_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01256">
        <property type="entry name" value="YfiT_hydrol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023774">
        <property type="entry name" value="Put_metal_dep_hydrolase_YfiT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DinB_2" evidence="7">
        <location>
            <begin position="40"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="186" mass="21509" checksum="CC63FB96C4DB21F9" modified="2014-06-11" version="1">MTEPIHDEAELEPLRYPIGRSADASESNPQQREEWIEHIRRLPDRLEEAIEGLNEEQLDTPYRDGGWTVRQVVHHLADSHMNAYIRLKLALTEEGPTIKPYAEGDWAKQPDASGMAVGASLLILRGLHARWTFLLESLAAEQWARTFYHPESREWSRLDTQTSHYAWHGQHHTAQITALRDRSGWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AML0</accession>
    <name>A0A011AML0_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative ring-cleavage extradiol dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0176</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the extradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282521.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.178"/>
    <dbReference type="HOGENOM" id="CLU_059557_0_0_9"/>
    <dbReference type="OrthoDB" id="1335734at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019439">
        <property type="term" value="P:aromatic compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000486">
        <property type="entry name" value="Xdiol_ring_cleave_dOase_1/2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00082">
        <property type="entry name" value="EXTRADIOL_DIOXYGENAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="4 6 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="7">
        <location>
            <begin position="11"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="7">
        <location>
            <begin position="169"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="284" mass="30664" checksum="E333BACA8D65D3AA" modified="2014-06-11" version="1">MSNYRIHPEAHMGRVQLKVSQIERSVRFYSEVIGLKLLAQTEKTAEFGVDGNEVLLGIEEVPQAQIMRPQSVTGLYHFAILLPNRTALGTTLRHLAETGMSIGQGDHLVSEAFYLNDPDGNGIEIYADRPRSEWQKDAKGEYVMATDPVDVESLLKLAGAWNGLPSGTIIGHVHLHVGNLPDARKFYVDGLGFDVVLHFGNAALFVSAGGYHHHMGLNTWAGVGAPAAPANAVGLKYFTIVYPNVSERDQAVAALRNAGIEVADTPEGQSALDPFGNRAVLVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AML5</accession>
    <name>A0A011AML5_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable transaldolase</fullName>
            <ecNumber evidence="9">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tal</name>
        <name evidence="10" type="ORF">SacsacDRAFT_0181</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the transaldolase family. Type 3B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="9"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282527.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.183"/>
    <dbReference type="HOGENOM" id="CLU_079764_0_0_9"/>
    <dbReference type="OrthoDB" id="784333at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00956">
        <property type="entry name" value="Transaldolase_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00494">
        <property type="entry name" value="Transaldolase_3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022999">
        <property type="entry name" value="Transaldolase_3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004731">
        <property type="entry name" value="Transaldolase_3B/F6P_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033919">
        <property type="entry name" value="TSA/FSA_arc/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00875">
        <property type="entry name" value="fsa_talC_mipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG83216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="227" mass="24458" checksum="DAEC92FDEDE64311" modified="2014-06-11" version="1">MKFFLDTGNLDEIKRIVRLGLVDGVTTNPSLIAKEGRQFQDVIKEITAIVPGPVSAEVVSLKGDEMIAEALEIAQWAPNVVIKLPMTEEGLYACSQLSKKGIRTNVTLIFSAAQGLMAAKAGATYISPFIGRLDDIGVDGMELISDLRTILDTYDLKSEIIAASIRHIGHVQQAALAGAHIATIPGSILPKLWAHPLTDKGIDQFLKDWESVPKAADSVKEKADTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMN1</accession>
    <name>A0A011AMN1_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ThrE_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">SacsacDRAFT_0196</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282553.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.203"/>
    <dbReference type="HOGENOM" id="CLU_117642_3_0_9"/>
    <dbReference type="OrthoDB" id="1567942at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024528">
        <property type="entry name" value="ThrE_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12821">
        <property type="entry name" value="ThrE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="ThrE_2" evidence="6">
        <location>
            <begin position="5"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="142" mass="15507" checksum="4FC51FFEFB9B81EE" modified="2014-06-11" version="1">MWAHFLTSFFAAAAFVILFNAPKKSLFHCGLVGMLGWVLYVFIRGEIGEAPATLAASLLVGILCQLFAKIYRTPVIIFSVAGIIPLVPGGMAYNAMRRFVENRYDEALQIGAQTLMIAGAIAAGLVLSEVLNQMMRRRPKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMR8</accession>
    <name>A0A011AMR8_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282588.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.226"/>
    <dbReference type="HOGENOM" id="CLU_023205_8_1_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="17"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="322" mass="36166" checksum="AFF3AF920A3AD9A4" modified="2014-06-11" version="1">MMKSMPLNARGIPASRLVLGCMPFGGEWDHSPLTEERVKLSEAAVEAALSIGINMFDHADIYTRGKSEEAFGRILKARPGLRDEIVLQSKCGIGLEGDGLPSLFDFSRDHILESVDGSLKRLGTDYLDILLLHRPDPLMEPEEIAEAFAKLKASGKVRYFGVSNMSVAQIRFIESELTDRLIVNQLEMGLGRLDFVEETVRVNQTRGTQVHFSDGLMEYSRSENVQLQAWGPLAQGKFTGRDVSGEPEHVQKTAKLVTQMAEDRCTTREAIVLAWLMKHPAQIQPVIGTMNPERIQACRDAQREADRMSREDWYRLYMTARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMS6</accession>
    <name>A0A011AMS6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide/dipeptide ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">SacsacDRAFT_0226</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.237"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_9"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="5"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="353" mass="39137" checksum="322391429863539A" modified="2014-06-11" version="1">MERLLEVKDLAISFRTRAGEVQAIRGVNFHLDKGETLAIVGESGSGKSVTSQAIMKLVPEPQGQYKRGQILFEGQDLVKKTQNQMQKMRGKEIGMIFQDPMTSLNPTMKVGKQITEVLFTHEKISAADARARGLELLQLVGIPNHEKRFNQYPHEFSGGMRQRVVIAMALAANPKLLIADEPTTALDVTIQAQILELMKDLQAKIGTSIIFITHDLGVVAKMADRVAVMYAGQIVEMGTAAEIFYDPRHPYTWGLLSSMPALDSNGEEKLTAIPGTPPDLLHPPVGDAFALRSNYAMKIDFEKEPPMFKVSDTHFVKSWLLHPDAPSVTPPEAVQRRQRKLDNAYETPVLVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMS8</accession>
    <name>A0A011AMS8_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HD superfamily phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506768.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_838981_0_0_9"/>
    <dbReference type="OrthoDB" id="370035at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="73"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="349" mass="38767" checksum="12856EC52E61FA4D" modified="2014-06-11" version="1">MERTEITNRHEKGSDGTYGQMAGPGALRDPLWGTIITPTAIEMELLRTNAVRRLHYVRHAGPASLHTQHTSTRLQHTLGVFACVAHFAPEWPELRAAALLHDVGHGPFSHALEGLEGFDHHRHSEEVLSSEQIHRALGGLNRQTVLDLIEGNAASPLRSREGVLHADHLDSWVRSAAAFGILPRPASELLSGFKLSGPHLEADADTAAQMIKLIVHEAYYHASADNIGPVAVLRALTQRLIGEGGLRGTEMGNLADEELLALLRRHPATAEETYRFLYRPQELRVVRSDEARPTEAYRHRLNKLYLTLPRIQGAVDPARLPDYPKLEALGGLLGEYHVFWEEGDIVEHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMU4</accession>
    <name>A0A011AMU4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_35_1_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="169" mass="19512" checksum="D78BCD8FACEAFA28" modified="2014-06-11" version="1">MSELIMRTAGSDDIMQLAEMRYDYTLEDHPELAVTDEQKRDYTDEMHEFLEEAIGSENWVVWVAEYGSEIVAHAYLEMIRKVPRPGKATQPFIYMTNVYTRPQHRGLGIGTRLTQVIEQWSRELDHDFIVVWPSGRGEDFYAKNGYTACSVPMELKLSVESGQKRSSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMU6</accession>
    <name>A0A011AMU6_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">SacsacDRAFT_0256</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.270"/>
    <dbReference type="HOGENOM" id="CLU_000445_89_36_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="176"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="237"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG83291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="435" mass="49799" checksum="88C42F442BB9540C" modified="2014-06-11" version="1">MSRPSFRLKLKVQLTAALVVAVVLAFLLFIALQSLGSTLLDRHFGQPSFVAQQNQKMIAELSEFVSQNRLSIHDDQRLNDWSSKKKYLTVYVYQDKKLVYSSDGFYVQAEGESAEPFVSDESLYNVSFTDADAQVFIESFAEYRYYTMVTFASLAVAFAFFLCAVLLLINVKTSYIEVLENEIKILEGGNLEYPITIKGKDELSSLAQSINEMRKSFIERLENEELARKANNELVTAMSHDLRTPLTALIGYLDIIQYRKYKSDEQLFKYIANSKDNAYRIKHLSDQLFEYFLVSYSQNDLLELDEYDGLPLLDQMIGTHAPLLMDEGFEFEFIPCNEPFTLSIHVISMQRVFDNLFSNLLKYADKSEPVTIVCTLQERWLYIHVKNRIKQGSVHADSNSIGIKVCEQIVQNHGGSFDVVRTEKMYSVEVSLPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMV4</accession>
    <name>A0A011AMV4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.283"/>
    <dbReference type="HOGENOM" id="CLU_013985_34_5_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="144" mass="16233" checksum="DBC230C9597FC3BB" modified="2014-06-11" version="1">MIEIRMLQVGDLPQLAVLYGELVEEKSSPEAMRGTFDKIASDDNYSLLGAFEDGRLAGSLMGVICEDLIGECRPFMVIENVIVSEAFRGKKVGKLLMQEAEWVARERRCGYALLVSSGFRKEAHAFYESLGYTENVRGFRRRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMW8</accession>
    <name>A0A011AMW8_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282711.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1642486_0_0_9"/>
    <dbReference type="OrthoDB" id="1941332at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="161" mass="18821" checksum="6866CF40D53A7C4F" modified="2014-06-11" version="1">MQENKRIHQVRSTQSRTLAVACGIQSGLWGTMAYQHYKSWVGGWAGQELIWLALFMTLFMLAFAIAAVWQSQRPAYMLRLGEDRIKLRRRELMSEAIKRIYISWEDNPSISIKPKGSLIVPNDLSFKFQEGTENERRVRELVSWAESHQVPIIKRKATRWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS51</accession>
    <name>A0A010YS51_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polyphosphate:nucleotide phosphotransferase, PPK2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506747.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.5"/>
    <dbReference type="HOGENOM" id="CLU_048699_1_2_9"/>
    <dbReference type="OrthoDB" id="953793at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016776">
        <property type="term" value="F:phosphotransferase activity, phosphate group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022300">
        <property type="entry name" value="PPK2-rel_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03709">
        <property type="entry name" value="PPK2_rel_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="1">
        <location>
            <begin position="34"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="290" mass="33559" checksum="F9299A1EFFDABC98" modified="2014-06-11" version="1">MKTKTQLCTGEKVSLDQIATDYPAEDRPDAPEIARKKKKLNRKLEHLQEKLFASRSHAVLFVFQGMDCSGKDGTINHVFSEVNPQGVLTHSFKAPTDEETEHDYLWRAHRHVPARGYIAAFNRSYYEDVLITRVHGTIEDKKAKKRFAQINDFENMLRENGIVVVKIFLHISKSFQLDKLIARIENPDKNWKFDPSDLAERKHWDKYQACYEDVLTECASSDLPWHVVPADDRAMRDLAVLRIAVDTLEKLDLEFPPPVPELQDLLPELYDERDNEAGNFKKSKNPKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS57</accession>
    <name>A0A010YS57_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282165.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.10"/>
    <dbReference type="HOGENOM" id="CLU_1524421_0_0_9"/>
    <dbReference type="OrthoDB" id="1311215at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="168" mass="18945" checksum="58E5F95076E2FAD7" modified="2014-06-11" version="1">MSQRFVIEAVMVAIYGQLLSANRPVEYIVPYTTVLELYEFEEGAEPLMNEPGDDQHVKEKVKELIAYFEEPLNKKKIQKALTIPWAKSAPILLGDQIKLSVINAVDNAHYGELFDPIETEVLLSSLKEEAPVLTDQLEMIQRIISAAVPIQVFDIDDFEFALEGTAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS68</accession>
    <name>A0A010YS68_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">2-oxoacid:ferredoxin oxidoreductase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">SacsacDRAFT_0020</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282182.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.20"/>
    <dbReference type="HOGENOM" id="CLU_020913_0_0_9"/>
    <dbReference type="OrthoDB" id="37118at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="POR_N" evidence="8">
        <location>
            <begin position="30"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="PFOR_II" evidence="10">
        <location>
            <begin position="279"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="9">
        <location>
            <begin position="551"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG83055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="768" mass="85074" checksum="7CCDB6FF7107B38E" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS74</accession>
    <name>A0A010YS74_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, ribosomal protein N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506750.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_773596_0_0_9"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="200"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="358" mass="41080" checksum="E34D23031FB9AA5C" modified="2014-06-11" version="1">MERGRISRMEQVIRESEPNALPIELLKQGDPLDWRIETYLHEAEWWSIRAATEEVLAVVGCLRMGAEEAEIVNIALKGRTAEELEQLIRLLQEVDTEWTQRGVRRLMAYIGAWETDLLYACQRAGFRIVAAEPDYYADFQLAPAEGSGLRRLDRLMLELLAQGRNSSEAVLRDVFGDRPVEQRPTIRRAELRDSRSLLSMKKRLDRETTSMLYEPGERRLTDGDQLEQIRSLLRSSNSLMLVAEMDGEVVGYLEATGGKVRRNQHTIYIVVGILEVCTGKGLGRRLFQEMFEWAARRQVLRAELTVQASNQRAYRLYRSLGFRLEGVMRGALMIEGEPVDLYQMGCDLRTVKQGRVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS81</accession>
    <name>A0A010YS81_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase, MG_246/BB_0505 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.30"/>
    <dbReference type="HOGENOM" id="CLU_068238_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005235">
        <property type="entry name" value="YmdB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36303">
        <property type="entry name" value="PTHR36303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13277">
        <property type="entry name" value="YmdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004789">
        <property type="entry name" value="DR1281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00282">
        <property type="entry name" value="TIGR00282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR004789-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004789-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="265" mass="29669" checksum="19DB8DDE67AC3892" modified="2014-06-11" version="1">MKLIFIGDIVGSPGRRAVKETLPYLKSKYNPHIVIANGENAAAGRGITHAIARQLFEQGVHGITMGNHTWDNKDIFEFIDDEPRMVRPANFPPGTPGRGYTVVKAGGKELALVNLQGRTFLPAIDCPFRAADEIVDELRRKHKCILVDFHAEATSEKIAMGWHLDGRASLVVGTHTHVQSNDDRILPGGTAYLTDAGMVGPRDGILGMQQEGVLYRFKTQLPSRFNVDEEGKWHFHGVYVDIDEDTGRARKIEKIRIMEDEWRME</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS91</accession>
    <name>A0A010YS91_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Zn-dependent peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282230.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="MEROPS" id="M16.A20"/>
    <dbReference type="PATRIC" id="fig|915437.3.peg.40"/>
    <dbReference type="HOGENOM" id="CLU_052317_0_0_9"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="1">
        <location>
            <begin position="61"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="2">
        <location>
            <begin position="181"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="426" mass="48787" checksum="4DCC94512846E921" modified="2014-06-11" version="1">MERIVYEHLQETLYYEKLDNGLGVYVLPKEGFQKTYATFSTNYGSVDNRFRVAGQEEHRVPDGIAHFLEHKVFEEPDGDVFLKFSTQGASSNAFTSFDQTVYLFSATEKIEENLETLINFVQNPYFTDENVEKEKGIIGQEIQMYQDNPDWRVYYGLIEALYSVHPVHIDIAGTVESISEISKETLYACYNTFYHPSNMLLFVVGGVDPQKVIEQVKRNQDAKNYGSQAEIERFFDPEPEQVSQERKELNLPVSLPKCLFGFKDPAPKVSGTELVKLDLTTEVMLDLLLGNSTPLYQKLYEEALITDGFGGDFRATPEYAFSVIGGDTRDPDLLIERIREEAAKLAETGFDEKAFERARKKKIGGYLRMLNSPENIAHEFTRYKFAGGDLFTVLELYENMTLDEVNARLREHIRWDRHAVSIVRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSA9</accession>
    <name>A0A010YSA9_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 9">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">infB</name>
        <name evidence="12" type="ORF">SacsacDRAFT_0055</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8 9">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282270.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.55"/>
    <dbReference type="HOGENOM" id="CLU_006301_5_1_9"/>
    <dbReference type="OrthoDB" id="347113at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="358"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="58"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="G-domain" evidence="8">
        <location>
            <begin position="361"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="59"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="367"/>
            <end position="374"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="413"/>
            <end position="417"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="467"/>
            <end position="470"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG83090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="855" mass="90879" checksum="0593DB380C0DC796" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSB9</accession>
    <name>A0A010YSB9_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282296.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.65"/>
    <dbReference type="HOGENOM" id="CLU_038505_1_1_9"/>
    <dbReference type="OrthoDB" id="1630604at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="82"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="211"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="258" mass="29730" checksum="30E873BA4A160805" modified="2014-06-11" version="1">MINRFRSWIGPKEREQASGPAEPSADNVPQHIAIIMDGNGRWAKRLGMPRIVGHQSGMKAVKRATIAADELGVRYLTLYAFSTENWSRPKEEVDFLMRLPQEFLALELEELIRKNVQVRMMGNMENLPEHTLKAMREATARTKDNTGLVLNFALNYGARRELVEGIREIAKRVEAGQVRAEDIDQAMISAHLQSVDMPDPDLLIRTSGELRISNFMLWQIAYSELWFTDAYWPEFGREHLREAVAEYQRRTRRYGGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSF6</accession>
    <name>A0A010YSF6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar operon protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282372.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.96"/>
    <dbReference type="HOGENOM" id="CLU_145226_0_0_9"/>
    <dbReference type="OrthoDB" id="1943154at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013367">
        <property type="entry name" value="Flagellar_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12611">
        <property type="entry name" value="Flagellar_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02530">
        <property type="entry name" value="flg_new"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="124" mass="13442" checksum="A0B800248AC21332" modified="2014-06-11" version="1">MNDPIRVGQLYPAKIPPVASRNQTASAAGKENFQTVLEEKLLKFSGHASKRLEQRGIQFDSEQLRKLGSAIDKAAAKGSKESLVLMQDMALIVNVRNRTVVTAVDGGSMKDNVFTQIDSAVIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSK4</accession>
    <name>A0A010YSK4_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UPF0122 protein SacsacDRAFT_0130</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">SacsacDRAFT_0130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UPF0122 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282442.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.130"/>
    <dbReference type="HOGENOM" id="CLU_129218_1_0_9"/>
    <dbReference type="OrthoDB" id="2008796at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00245">
        <property type="entry name" value="UPF0122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007394">
        <property type="entry name" value="UPF0122"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40083">
        <property type="entry name" value="PTHR40083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04297">
        <property type="entry name" value="UPF0122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG83165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="118" mass="14205" checksum="DD042DE6EDDF5495" modified="2014-06-11" version="1">MSQENRLEKTNRINLLFAFYEQLLTEKQQTFLKYYFHDDFSLGEIAAEFEISRQAVYEHIKRAEQTLENYEAKLELLQRHDRRMQEIRELGTLANDEKLPEQVRSQLEIIAQKLQALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSP9</accession>
    <name>A0A010YSP9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282503.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.167"/>
    <dbReference type="HOGENOM" id="CLU_133275_0_0_9"/>
    <dbReference type="OrthoDB" id="1390922at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="142" mass="15716" checksum="A4075372281BD3E4" modified="2014-06-11" version="1">MLQSITEQVRDPRVAALLELAVFPDPEQVERAIAFYEQNAEAELLAYIEQGEMLGVVGFTPSGDKEITVTHIAVDPGSRGLGYGRGMLLDLMVQERPERVIAETDEEAVDFYRSVGFSVTGLGESPSGLERFRCVYEADEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSR3</accession>
    <name>A0A010YSR3_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9 11">Uracil-DNA glycosylase</fullName>
            <shortName evidence="9">UDG</shortName>
            <ecNumber evidence="4 9 11">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ung</name>
        <name evidence="13" type="ORF">SacsacDRAFT_0175</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9 11">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 11">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 11">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="4 9 11"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282518.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.177"/>
    <dbReference type="HOGENOM" id="CLU_032162_3_1_9"/>
    <dbReference type="OrthoDB" id="1260295at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 9 11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="12">
        <location>
            <begin position="50"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9 10">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG83210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="237" mass="26827" checksum="0DCA28DD178C58EE" modified="2014-06-11" version="1">MKPIFENDWADILHPEMQKPYYLELRRKLADEYRSRTVYPDMYRIFSAFHLTSFADTRVVILGQDPYHGPNQAHGLSFSVQPGIQVPPSLDNIYRELQDDLGCQPVRHGFLEHWAKQGVLLLNNVLTVRRGAAASHQGMGWEAFTDAAIAAINECETPVVFILWGRSAQEKGSFIDGTRHLILKSAHPSPRSADRGFFGSRPFSRTNAFLREKGLSEINWCLPESPEGLKEEGETTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSS6</accession>
    <name>A0A010YSS6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282534.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_18_6_9"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="150" mass="17393" checksum="51A58255DC16D2C2" modified="2014-06-11" version="1">MYQPQDSIGFQLGVIYRKVSNRLAANLKDYDLTPEQWSVMCCICFKEGMNQKEIAERTVKDQPTVTRILNVLHRKGLIMRSSDRADRRAYLIYPTEKGRQVTEETSVIERHHNAAMIEDFSPEQLELLAEAFRKIERNAERYGDGPAIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSU0</accession>
    <name>A0A010YSU0_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ThrE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.202"/>
    <dbReference type="HOGENOM" id="CLU_070277_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="ThrE" evidence="2">
        <location>
            <begin position="13"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="251" mass="26752" checksum="6D5D6E437F0C2E80" modified="2014-06-11" version="1">MEQKTSIYETIELCLLAGKVMLQSGAETYRVEDTMVRIATAFGLSESHSYVTPTVIMFSTSGEQPAKLIRIEERTTDLNKIAEVNAISRQIASGELSARDAKTLLLKAESAPFGYKLPVQILAAALTSACFLIMFGGTWPDFPAAFIAGGAGLAASVWLHRIVQVKFFAEFSAALLVGLLALLFIWGGFGYEFDRIAVGSVMPLVPGLLITNAIRDLMAGHLVSGISKGADACLTAFAIGAGIAVALIFFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSU6</accession>
    <name>A0A010YSU6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282565.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.207"/>
    <dbReference type="HOGENOM" id="CLU_061176_1_0_9"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="294" mass="31802" checksum="C283BC902E6BE6A6" modified="2014-06-11" version="1">MTQNVLVLGGTRFFGKVLVDKLLEAGHAVTIATRGNTEDPFGDRVERIKVDRTDEAALAAATEDRRFDVVYDNICYTADEARAAIRVFEGKVGHYVLTSSLSVYGTGSADMHEGLLDTAALEVPPSPVGQVSYGEGKAQAEAVFFREAPFPASAARFPIVLGPNDYTKRLHFHVDRIKNGVSFVMPNTEARICFIHEEEAADFLKWLGESGVTGPFNAASAGKPKLRKLLATIDQEAGGAVIVLSEGPDSEASPFGIPDDWAMDTSKAEHAGFVFRKLDDWLPGLIGMIAREEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSX9</accession>
    <name>A0A010YSX9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081833_1_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009793">
        <property type="entry name" value="DUF1361"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07099">
        <property type="entry name" value="DUF1361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="243" mass="27659" checksum="0ED99787F30989F8" modified="2014-06-11" version="1">MNQLKSMQYPWKLYMWLVLLLLTVIDLAVLLDIRNGAGGRPYRFMLWNFFLAWIPVAAAAGLDGLSLLRKGAARTVLLGLGGLTWLFFLPNATYLLTDLLHVFRIYSFDPQDRYWGDIGFWRHLLPMLLASMLGLLIACAALHSVHRLVERAFGWVNGMVFACAVLLLSSFGVYMGRFVRWNSWDVIGNPLMLVKDMRDLFSDPEWVRHLILFGGGILALQAGMYAVLYLFAKMNPGEKEHES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSY3</accession>
    <name>A0A010YSY3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282596.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1853226_0_0_9"/>
    <dbReference type="OrthoDB" id="2102247at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458886" evidence="1">
        <location>
            <begin position="34"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="146" mass="15994" checksum="5294B9693726742D" modified="2014-06-11" version="1">MNRKRNQTLAIIGGSVAVLAILALVIFLVYARATPQENPFNLQMGQTLNADETGVTDNATSFSRTKPIYVIADYPDDGVTLDHTAILSVISESSGQVIQKTEVEEDGTTKQLRMDLENADWEPGIYELTFARSGTMVGTINFSLHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSY8</accession>
    <name>A0A010YSY8_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fructose-2,6-bisphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033323_12_2_9"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="210" mass="23771" checksum="A3F926E7615B3779" modified="2014-06-11" version="1">MNIADRGADDIDTETVLYFVRHAHSKYEHGRELERGLSDSGKAEAMAVCRRLEKEKIEVFVSSPYQRAVETLAPLAEYAAKTIKLYDALHERLVSGEQDLGPERFAEAKRRCYEDPDYCPPGGESSRQARSRALPVIGQLLREHAGKRIAVGTHGDVLTLMLGSWDPQYDYSFWQQLSMPDVYRVRFDGMAFAGAERIRYNSSVSLEQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT14</accession>
    <name>A0A010YT14_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fructose-2,6-bisphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282682.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.287"/>
    <dbReference type="HOGENOM" id="CLU_129249_0_0_9"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="177" mass="20487" checksum="1F416FB8BB741004" modified="2014-06-11" version="1">MAIFYLIRHGEPDWHTYKPLNLKGNGRDLVPLTPHGRSQILETAEDPRLGRAELILSSPYTRAMQTAAILSRRLDLDIAVEYDLREWQPDLTFEYNTEERMRELRDDYNRCGGTHPTGERKLWESRDSLLRRIEGVLDRYRKYSNVIVAGHGTIFGTLVGRADIAQGEIVEYEVREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT34</accession>
    <name>A0A010YT34_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Arabinose efflux permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">SacsacDRAFT_0291</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506780.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.308"/>
    <dbReference type="HOGENOM" id="CLU_001265_23_0_9"/>
    <dbReference type="OrthoDB" id="1210653at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="11"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG83325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="401" mass="42373" checksum="BC0C3A34B0E174EA" modified="2014-06-11" version="1">MFKARVSPRWSALLSLLFALACGLAVANIYYAQPLLGQLAQEFGVPPATIGYIIAVVQLFYAFGLILIVPLGDLMNRRRLILLQLLGIALALAFVGFAQDYAGLLAGLAAVGLMAVVTQVLVNFASALAPTTERGKAVGVVTGGVVIGILLARFFAGAISELADWRAVYLTSSGLTLLVALILVVMLPQDDSGKPGLSYNQLLRSMLKLFVQEKLLRIRAAFAFFIFTAFGMLWTPLSLPLSEAPLSLSPSLIGAFGLAGAAGAIGAARAGKWADRGMGNRATGIALVLLLVSWLPISMLHHSLLLLIAGILLLDFAVQVVHVTNQSLLFAALPEARGRLTGAYMVFYSIGSAAGAILSTWAYAAYGWSGVCWIGAMVSAGGCLLWVWTRVSKKALFGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT39</accession>
    <name>A0A010YT39_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506782.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1209102_0_0_9"/>
    <dbReference type="OrthoDB" id="1650104at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="229" mass="26335" checksum="0585420A863409BF" modified="2014-06-11" version="1">MLIPDNEQTMERLKAFICKWAGPAKPEYGIRRESVPTDLPAVLRDFYAFAGNWPNPSYEASAYPAGFRPKLFEAQDIWLEPEELKRESGRISFLLENQGSWSCEVDADQDDSPVYSDAARLWDERLEESEVVCPSLSHFLTTFCLQELVFGSRYFGKLEGALDPDVFRAKLHPLWLDGYYVFKEPSHSFYLCGDNLLIMDYYSDVWYGCLEESALSLILDPNMVKPIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6V2</accession>
    <name>A0A010Z6V2_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rsgA</name>
        <name evidence="7" type="ORF">SacsacDRAFT_0008</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.8"/>
    <dbReference type="HOGENOM" id="CLU_033617_0_1_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="6">
        <location>
            <begin position="142"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="5">
        <location>
            <begin position="148"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="363"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="187"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="241"/>
            <end position="249"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="399" mass="43995" checksum="E416BECDCB2CDB08" modified="2014-06-11" version="1">MNKTMKSINEIVNNSADTQDMQQSGVSAIKKTEEERIFQEAYGWDSSWQEAWLAAGFEAAGLTPVRMTADFGQQFKVATAAGEYTAETSGKMRHSTEHGAELPAVGDWLAAECLPGERRARIHGVLPRRSKISRKAAGNPVREQIIATNVDTLFLVTSLNYDLNIRRLERYLIMAWNAGAQPVILLSKADLCDEAFRLQALSEVSLAAPGVPFHIVSAQTGEGMEQAAGYFAGGRSCALAGTSGCGKSTLTNYLAGGHVQRTSDIREDDSRGRHTTTHRQMFEIPGGGVLIDTPGMRELQLWEGEEDGMSGTFSDIESLAGNCRFRDCSHNREEGCAVREAMNDGELDSGRLGSYRKTQRELAFLERKEKSRSATGRNAGNGKRDQRKERRDKNWLHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6W0</accession>
    <name>A0A010Z6W0_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative GTPase, G3E family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282176.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.18"/>
    <dbReference type="HOGENOM" id="CLU_017452_1_4_9"/>
    <dbReference type="OrthoDB" id="1267701at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="231"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="324" mass="35837" checksum="C5C46AB35C07A853" modified="2014-06-11" version="1">MNKDVPVYLLSGFLGSGKTTLLQKLVAYWQGQGLKPGVIINELGDVNLDGMLVDSEVPTAELLGGCICCTVREDLAGELAMLVERDRPDVVLIEATGAANPIDLLDSATETAMYAGIDIKGLITVADAAHLLEMYRNRGGRTYALMQDQIRCASVIILNKMDRVSEREAEELERAITEWNAYAPVVRAIRCEVDFEALLNIGFAAERVENGPLKKTPGGRFDMLGSGHEHVTSYTHRFKNPVDSERFEALISSLPREIYRAKGLLTFSDTASRFLFQYAFRELDFIKVTPQGKLDDMAVFIGEHFSAAELREKLEALEAEEAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6W7</accession>
    <name>A0A010Z6W7_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Phosphate propanoyltransferase</fullName>
            <ecNumber evidence="4 7">2.3.1.222</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0028</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>phosphate + propanoyl-CoA = CoA + propanoyl phosphate</text>
            <dbReference type="Rhea" id="RHEA:28046"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:58933"/>
            <dbReference type="EC" id="2.3.1.222"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Polyol metabolism; 1,2-propanediol degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PduL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.222" evidence="4 7"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282196.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.28"/>
    <dbReference type="HOGENOM" id="CLU_080676_1_0_9"/>
    <dbReference type="OrthoDB" id="1156172at2"/>
    <dbReference type="UniPathway" id="UPA00621"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051144">
        <property type="term" value="P:propanediol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008300">
        <property type="entry name" value="PTAC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39453">
        <property type="entry name" value="PTHR39453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06130">
        <property type="entry name" value="PTAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010130">
        <property type="entry name" value="PduL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR010130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="190" mass="20292" checksum="673A020DAFAE34FF" modified="2014-06-11" version="1">MSKIVPVGVSARHIHLSQEHVETLFGQGYQLTEMKALSQPGQFAANETVEVVGSKGTFPKVRILGPARPATQLEISQTDSFALGVKAPVRESGKTSGTPGILLKGPAGEVQIEEGVIVAARHIHFHTSDAAKWDIQDQQLLKVRFGGDRGVVFENVIARVSDSFALDMHIDTDEANAVLAKTGDTAEIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6X1</accession>
    <name>A0A010Z6X1_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recA</name>
        <name evidence="12" type="ORF">SacsacDRAFT_0033</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the RecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037291665.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.33"/>
    <dbReference type="HOGENOM" id="CLU_040469_3_2_9"/>
    <dbReference type="OrthoDB" id="1080436at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="10">
        <location>
            <begin position="34"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="11">
        <location>
            <begin position="198"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="327"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG83068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="353" mass="38278" checksum="30B42601C31C4172" modified="2014-06-11" version="1">MSDRRAALDMALRQIEKQFGKGSIMKLGESTHMNVEVVPTGSISLDVALGTGGMPRGRIIEIYGPESSGKTTVALHSVAEVQKAGGQAAFIDAEHALDPKYARKLGVNVDELLLSQPDTGEQGLEIAEALVRSGAVDIIVIDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLSGAISKSNTIAIFINQLREKIGVMFGNPETTPGGRALKFYSSVRLDVRRIESIKMGNDVVGNRTRIKVVKNKVAPPFKQAEVDIMYGEGISKEGSLIDMGTDMDIVEKSGAWYSYSGERLGQGRENAKQFLKEHKDIAFAIETKIREASNLTTAIEPPTEADKKAEEQEEQELLELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6X5</accession>
    <name>A0A010Z6X5_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282224.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.38"/>
    <dbReference type="HOGENOM" id="CLU_1000798_0_0_9"/>
    <dbReference type="OrthoDB" id="1069145at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024514">
        <property type="entry name" value="DUF3388"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016784">
        <property type="entry name" value="UCP021288_ACT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11868">
        <property type="entry name" value="DUF3388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021288">
        <property type="entry name" value="UCP021288_ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="1">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="255" mass="29322" checksum="81F3C14B3CAB3BB7" modified="2014-06-11" version="1">METKQWYMEYRIHKNRPGLLGDIASILGMLEVNIITINGVEGRTRGMLLETTDDEKIQLLGDMLKKVDSVTVTALRPPKLVDILAVRHGRYIDRDSDDRKTFRFTRDELGLLVDFLGELFKREGNQVIGLRGMPRVGKTESIIAGSVCAMKHWTFVSSTLLRQTVRSQMSEDEMNPNNVFIIDGIVSTIRSNEKHYQLLNEIMAMPCTKVIEHPDIFMRESDYDYAQFDMIIELRSTPDEEIVYDTFATSYTDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6Z1</accession>
    <name>A0A010Z6Z1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exopolyphosphatase-like enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282266.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.53"/>
    <dbReference type="HOGENOM" id="CLU_039720_0_0_9"/>
    <dbReference type="OrthoDB" id="1040743at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="1">
        <location>
            <begin position="22"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="2">
        <location>
            <begin position="237"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="325" mass="35647" checksum="C4139F9D8312FB06" modified="2014-06-11" version="1">MRTYEQDLIGARQFIEQHDDFLVVAHVQPDGDAVSSTLAVGWLLSRLGKTFTMINEGPIPQRMTYMEGSEQILDMSLTERTRTYGNVICVDCADFKRVGLVSEWMEEGSNMLNIDHHPTNDEYGTQTLIKADAAATAEILYDLVKLFDLGWDRNIAEMLYTGILTDTGGFRYSSTSPKVMRIASHLLELGVNGPDLADSLLEQLTKPQFDVLTLSLATLQMSENGKVAWVHVTPEHMVQAGASNEDLEGIVNYPRNIQGVEVGVLFKVINENAVKASMRSAGKVDVAAIAAEFGGGGHVRAAGCRLEGTLEQVTALVIERIKQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z700</accession>
    <name>A0A010Z700_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <shortName evidence="7">DXP reductoisomerase</shortName>
            <ecNumber evidence="7">1.1.1.267</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">1-deoxyxylulose-5-phosphate reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dxr</name>
        <name evidence="11" type="ORF">SacsacDRAFT_0063</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="7"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282292.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.63"/>
    <dbReference type="HOGENOM" id="CLU_035714_4_0_9"/>
    <dbReference type="OrthoDB" id="1200722at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="SSF69055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DXP_reductoisom" evidence="8">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DXP_redisom_C" evidence="9">
        <location>
            <begin position="143"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="DXPR_C" evidence="10">
        <location>
            <begin position="258"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG83098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="378" mass="40990" checksum="1DE45935664C5CE7" modified="2014-06-11" version="1">MKKIALLGSTGSIGTQTLQVAAEHPEHFQVEALAAGGNTGLLLEQIRQFKPAKVSVATKEAAESLKSQVPAGTKVYFGNEGLIEIAAGTDADTVVTAVTGSMGLPATLAAIDEGKNIALANKETLVTAGHLVMRRAAEKGVPILPVDSEHSAIFQCLNGEPRERLSGITLTASGGSFRNLSRAELANVTVEDALKHPNWSMGSKITIDSATMVNKGLEVIEAHWLFGLSYDEINVLLHPESIIHSFVEFEDTSIIAQLGNPDMRVPIQYALTYPDRIPLKANRLSLAEIGKLNFREMDFGRFPCLRMAYDCGRMGGTAPTVFNAANEVAVARFLRREISFLQIEETLEKVMQQHTAIADPDLDVIREADQWARRVASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z710</accession>
    <name>A0A010Z710_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative polymerase with PALM domain, HD hydrolase domain and Zn ribbon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506752.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.74"/>
    <dbReference type="HOGENOM" id="CLU_026157_2_1_9"/>
    <dbReference type="OrthoDB" id="379544at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005646">
        <property type="entry name" value="FapA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38032">
        <property type="entry name" value="PTHR38032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03961">
        <property type="entry name" value="FapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="467" mass="51054" checksum="F863A8D208E5A68B" modified="2014-06-11" version="1">MVEHLALDRHLAVSFDASKMSAHLRFVKPEEGFACTEESLRQFLNDQNVRFGLIDEAIGRFVASPASYFFEEIEVARGIPAVDGQNGYIEFMFEKEDEARPMEREDGRVDYKELIRLKNVGKGQLLARRHPSRPGTPGTGVTGEEIAFKPGKEARFKIGKNVVTDENHTSLYATIEGMVSRTDNGKINVFTVYEVHGDVDYSSGNVDFVGTVVIRGSVLPGFRVKAAGDIRVQGGVEGAELYADGSIEITGGVIGYHKGIVKAGMNVKSSFIQDGNVEAGEDIIVSQSIMHSEVRAGKNVICSGTKGLIVGGHIQAGEGVIARTIGNTMATATAIEVGVLPNLRNELADLHKRMRETADNMQKTTQALGLLDQMALAGTLGADKLALRAKLSVTKRQQDQERSHCKERIFEIEHILEDTGRARVVVNDTIYGGAKIVIGRYTKFMKETSSRVSFQYLEGDIVMSANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z715</accession>
    <name>A0A010Z715_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chemotaxis signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282331.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.79"/>
    <dbReference type="HOGENOM" id="CLU_048995_3_1_9"/>
    <dbReference type="OrthoDB" id="1711729at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="153" mass="17040" checksum="EDC0825C6E278F7C" modified="2014-06-11" version="1">MAEQIKVIVFALGNEEYGIDVDKVRTIERMMPITRVPKTYSFIKGVINLRGVVIPVIDLRGRFNLEESEYTDQTRIIIVAVGDMEVGFIVDAANDVVDLDRDNIDSPPEVVGGVKAKYLDGVAKVGEDRLLIMLNLAEVLNRGEVAHLEQLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z760</accession>
    <name>A0A010Z760_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate--CoA ligase [ADP-forming] subunit alpha</fullName>
            <ecNumber evidence="2">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="2">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sucD</name>
        <name evidence="7" type="ORF">SacsacDRAFT_0113</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282405.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.113"/>
    <dbReference type="HOGENOM" id="CLU_052104_0_0_9"/>
    <dbReference type="OrthoDB" id="1081709at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA_binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="105"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2 3">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="309" mass="31849" checksum="D2920CB59353AE80" modified="2014-06-11" version="1">MSILVDKNTKVITQGITGETGLFHTKGALEYGTQMVGGVTPGKGGTNVEITLENGSSVKLPVFNTVNDAVKETGATASVIYVPPAFAADSIMEAIDAELELVICITEGIPVLDMVKVKRYLEGKKTVLIGPNCPGVITPEACKIGIMPGYIHKAGKVGVVSRSGTLTYEAVHQLTTRGIGQSTAVGIGGDPVKGSEFIDILKLFNEDEGTQAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGATAPPGKRMGHAGAIISGGKGTAAEKIAKLEECGIRVAPTPAEMGATLVAVLEERGVLETFTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z790</accession>
    <name>A0A010Z790_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="5">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsY</name>
        <name evidence="7" type="ORF">SacsacDRAFT_0133</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282451.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.134"/>
    <dbReference type="HOGENOM" id="CLU_009301_3_0_9"/>
    <dbReference type="OrthoDB" id="656414at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="6">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="125"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="207"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="271"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="339" mass="37167" checksum="C57A2A4B7A434B69" modified="2014-06-11" version="1">MSFFRKLKESIAGKTDAVTKQFKDGLEKTRKGFVEHVSNLMVRRRKIDEEFYEELEEILIGADVGVNTVMGLIDELRAEVKKRRLSDASELRPVLSEKLVELLRGEQDNSLNMSQEGPTVILFVGVNGVGKTTTIGKLAHKFKSEGKKVLLAAGDTFRAGAIEQLEVWGTRTGVEVIKQSPGSDPAAVMYDAVQAAKQRNADILICDTAGRLQNKSNLMDELNKIFRVIQREIPGAPHEVLMVLDATTGQNALSQAKLFGEKSGVTGLVLTKLDGTAKGGIVVAIRQELNIPVKLVGLGEKMEDLQEFDSEQFVHALFAGLIEEELIEGEEGESDSSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z798</accession>
    <name>A0A010Z798_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="5">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">SacsacDRAFT_0138</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="5"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282460.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.139"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_9"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="14"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="65"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="157"/>
            <end position="161"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG83173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="249" mass="26181" checksum="36320958434DD49A" modified="2014-06-11" version="1">MEQPIKGQNALVTGASRGIGRAIALELGRRGANVAVNYAGNEASALEVVRELEALGVKAAAFKANVGKSAEAEELVKSVAAEFGSVDILINNAGITRDNLVMRMKEEEFDDVIETNLKGVFNCIKAVTRPMMKQRSGKIVNISSVVGAIGNAGQVNYTAAKAGVIGMTKSCAREFSSRGITVNCVAPGFIDTDMTDVLSEEIKTGLLAGIPLNRLGRPEEVATAVAFLVSPDASYMTGQVLHVDGGMYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7B5</accession>
    <name>A0A010Z7B5_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="6">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaD</name>
        <name evidence="8" type="ORF">SacsacDRAFT_0148</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial CoaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="6"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282478.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.149"/>
    <dbReference type="HOGENOM" id="CLU_100149_0_1_9"/>
    <dbReference type="OrthoDB" id="1846503at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="12"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="16"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="95"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="130"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="167" mass="18981" checksum="0801BEFE8C3D5946" modified="2014-06-11" version="1">MEQEKKIERIAVYPGSFDPVTLGHMDIIHRAAKQYDRLIVAVLNNLSKKPLFSVEERAELLRQATADLPNVEVDVFRDLLVNYVDQKKAQVVVRGVRSVTDFEYELQIATTNRKLNENVETIFMMTNPIYSYLSSSVVKEIAQFDGDVSELVTPEVRAALKAKLHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7C0</accession>
    <name>A0A010Z7C0_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Beta-galactosidase</fullName>
            <shortName evidence="6">Beta-gal</shortName>
            <ecNumber evidence="3 6">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">SacsacDRAFT_0153</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3 6"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282486.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.154"/>
    <dbReference type="HOGENOM" id="CLU_012430_1_1_9"/>
    <dbReference type="OrthoDB" id="831762at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013739">
        <property type="entry name" value="Beta_galactosidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013738">
        <property type="entry name" value="Beta_galactosidase_Trimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003476">
        <property type="entry name" value="Glyco_hydro_42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013529">
        <property type="entry name" value="Glyco_hydro_42_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36447">
        <property type="entry name" value="PTHR36447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02449">
        <property type="entry name" value="Glyco_hydro_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08533">
        <property type="entry name" value="Glyco_hydro_42C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08532">
        <property type="entry name" value="Glyco_hydro_42M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001084">
        <property type="entry name" value="B-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Glyco_hydro_42" evidence="10">
        <location>
            <begin position="14"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_42M" evidence="11">
        <location>
            <begin position="398"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_42C" evidence="12">
        <location>
            <begin position="616"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001084-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001084-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001084-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG83188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="675" mass="77007" checksum="2634E155B639B124" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7F8</accession>
    <name>A0A010Z7F8_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphatase, C-terminal domain of histone macro H2A1 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282525.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.180"/>
    <dbReference type="HOGENOM" id="CLU_046550_5_1_9"/>
    <dbReference type="OrthoDB" id="1812319at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="187" mass="20159" checksum="13D88EC43247A639" modified="2014-06-11" version="1">MQTKINEVTIKVIRGDITEYATDAIVNAANSSLLGGGGVDGAIHRAGGPAILEECRKIRDRQGGCDTGEAVVTTAGKLPAKFVVHTVGPVYQNGNKGEAELLKRCYANSIQAAVDVSARRVSFPNISTGIYGYPKKEAAEIAVTAVKEVIQAHSAESGETFLEEVAFVCYDEENERLYRQLLEKKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7G6</accession>
    <name>A0A010Z7G6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">SacsacDRAFT_0183</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282532.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.186"/>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_9"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="8">
        <location>
            <begin position="140"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="6">
        <location>
            <begin position="140"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG83218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="244" mass="26796" checksum="DE5FB081FA173A46" modified="2014-06-11" version="1">MHQPAKILIVDDEKAIVQMIEMVLRKEGFEHIHTAGTAAEGMRLLGEYGADVILLDVMLPDRTGFELGPQIRAMSDAHLIYLTARTTDLDRLTGFAVGGDDYVIKPFNPLEIAARIKARLRRGNAEPSSSAPAAAPADSRQRYDFGGFVLDERAGELRVGGDPVPCPAQAYQLLLFLCRNPNIVFSKSQLYESVWGFDGASDDNTVMVHIRKIRERIEADPGAPKHLLTVRGLGYKLVKGQASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7H3</accession>
    <name>A0A010Z7H3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Family 31 glycosyl hydrolase, alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0188</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282540.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.193"/>
    <dbReference type="HOGENOM" id="CLU_000631_10_0_9"/>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gal_mutarotas_2" evidence="3">
        <location>
            <begin position="158"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="771" mass="86426" checksum="0B011C47A27684D4" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7J1</accession>
    <name>A0A010Z7J1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0203</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the auxin efflux carrier (TC 2.A.69) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282572.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.211"/>
    <dbReference type="HOGENOM" id="CLU_056175_4_0_9"/>
    <dbReference type="OrthoDB" id="2033473at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="310" mass="32674" checksum="00E4AA0512E70052" modified="2014-06-11" version="1">MSSSFASILVQVFVPLAFPVVAGILLKRIKGLDTKPLSVVALYLLSPSIIFTTLLDAQVSAEDIGITVSFSFINLLTMWGVSVLLGRLLKLGDSEKSGLTLVASFTNCVNYGLPLVLLAFGQAGLHKAAVYIVLQIIIVNTIGVFFAARSHFSVKKAGLAVLKLPALYVAALAGLLRLSGTTLPESFATGVDLLAAAYSPVVLVILGAQMASRASGEWEPRLQKAFQAGLALRLAIAPLLSWLTLTLLGADRLLLGVLLVLASMPTAVNAVILAEQFNASPKFVSRCILWTTVASFVVLPVLILFAGTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7L1</accession>
    <name>A0A010Z7L1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative intracellular protease/amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506765.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.218"/>
    <dbReference type="HOGENOM" id="CLU_000445_44_5_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="2"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="209" mass="22973" checksum="9B4BB6B6F27D684D" modified="2014-06-11" version="1">MKTHILVYDGFSQFEVVLAAHLMKRAGEIVTVGLSTEPIVAHEGFRILPHTTIERVEAFSVDLFVVPGGDLSKITRRNELENLLKAIQSCGGKVGAISSGTLLILDAGLARDRRFTSPEPVENALAGNRIDQPVVTDGSLVTAKSHGYVDFALELGRLTGIYRDEADYEKTLRFFKFFMPAEETTIPVTTPVQKASEQSQPSDAEKVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7N1</accession>
    <name>A0A010Z7N1_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4261 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282604.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056940_0_0_9"/>
    <dbReference type="OrthoDB" id="642722at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025357">
        <property type="entry name" value="DUF4261"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14080">
        <property type="entry name" value="DUF4261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4261" evidence="2">
        <location>
            <begin position="231"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="326" mass="36857" checksum="92EC7EDC1AF52D7A" modified="2014-06-11" version="1">MTDERNRLDENGEEAELDRQTEEMLAADQDFGFARVYTIELKYKEKPKFSRKRLYEKMTLYTGELQQPEEQKSGSSLAVWEPSEESETDMLHFFHLNYLVSFADGDMPAQTSLMPTNHRPASEYETAVQQAWHWPDAGAILEECGHSLFLTDMMASGLEPKDRLRLITGTLRAVLETAPCDAVYFRESDKLLEPGDYLTAIEAGAILYGAMNVRFFNVQGTGSEQEEMLMDTVGLTALGVPDVQCHYFDLEPGEVAQYLTNLGYYLFDRGDVIQDGETFGPTEDVRWRCEHQYALAGPHRLVVDVDPGQPHYAGKQTAALADKPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7Q1</accession>
    <name>A0A010Z7Q1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282638.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_789611_0_0_9"/>
    <dbReference type="OrthoDB" id="2112676at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458977" evidence="1">
        <location>
            <begin position="41"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="351" mass="38044" checksum="F20D0AFB203E4338" modified="2014-06-11" version="1">MKPYTLPGMKKCASAALACGILFSGTFYGDAFTPSTYAAADSVNVQASQTQSVDWNKPEKIAMLQKLAMSSWAAGDFYSDPDNARYQAVKAASDQCYALLLDSTSSTSKLNAASVTLDSALTSYIEEYIRDASLLERQTFQMVRMLNASIGTTPGTYPQSAADSMFTIIDQAQAVAYDETATVQQFRQEYRNYIDGAAALRDAMHFDRAEKQDALGVKRQEAEQLAAGQANDADVQKLLNDFRAQANGLESLLDGTSGLLAVEAAERNVQTTYDKLAEAALLSAELAQARKMLDSPKGIRSGQYPSSAFGELRKAINKSALTLSRTSTQAQLKEARTTLAEAVVRFQSTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7Q9</accession>
    <name>A0A010Z7Q9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0258</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282651.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.273"/>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_9"/>
    <dbReference type="OrthoDB" id="1752365at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="5"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="259" mass="28918" checksum="C18FD3D93B46EAC1" modified="2014-06-11" version="1">MASVIELQNVSWRRGENMILQDINWTVEEGQHWAVLGLNGSGKTSILNMINGYMWPTSGEISVLGHRFGTIDLRELRKSIGWVSSSLQEKIRPNEQALEIVISGRHASIGLYAEIEQADREKAEELMRDLGCSHLIGRAYQTCSQGEKQKLLIARALMASPKLLILDEASNGLDFISREALLQSIDALSSRPDAPTLLLVTHHTEEISPVFSHSLLIRRGEIFAQGRSNEILSDGNLSDFFEMPVGVEWRGGRAWLSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7R3</accession>
    <name>A0A010Z7R3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mn-containing catalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the manganese catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282664.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.279"/>
    <dbReference type="HOGENOM" id="CLU_057467_1_0_9"/>
    <dbReference type="OrthoDB" id="1420351at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01051">
        <property type="entry name" value="Mn_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007760">
        <property type="entry name" value="Mn_catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039377">
        <property type="entry name" value="Mn_catalase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05067">
        <property type="entry name" value="Mn_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="300" mass="33250" checksum="A70122AF009ED0CD" modified="2014-06-11" version="1">MFKRMEEIMIEIPDVEKPDPNAAAAVHELLGGKFGEMSTLNNYLYQSFNFRSKSKLRPFYDLVMSITAEELGHVELVSHGINKIMQGSTSPGDPDKNPLESVKDARFSYPFLAGAQGAMPFDSMGNPWTGANVFNSGNLVEDLLHNFFLECGARTHKMKVYEMTDHPAARAVVGFLLVRGGVHVVAYAKALEVATGVNVTKLIPIPSLDNRKFNESRKYEEKGVHTKLYTWSDNDFTTIDQIWKGTHPEDGSALEVIHGVPKGVPIPEAPPLDEEFAPGISADEFKEIAKRLKQSGNIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7R6</accession>
    <name>A0A010Z7R6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282677.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1915608_0_0_9"/>
    <dbReference type="OrthoDB" id="2065005at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="132" mass="14369" checksum="8D00DD9B546EDB8F" modified="2014-06-11" version="1">MKKIIIGSVLTLAGTWIVGFIFIAAVLFVPNMSSWDGTRVWYAIFGGGPYEADLKQSMALGLPFAIGVLMFAAGIVILAIEFFRPESNRERMPSPVRPTPSQGNGGPKLPTFPADQPRAKEEDIPTMKEVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7S1</accession>
    <name>A0A010Z7S1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282685.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1524074_0_0_9"/>
    <dbReference type="OrthoDB" id="1103409at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="176" mass="20017" checksum="978BF73183C0FF94" modified="2014-06-11" version="1">MIVQTVLIRWMKNTRGEPYASLRTRQPAAFPLPAAIPTNPYPLEKERILMHRLIFHQTVKGIEQMDDTCEWLPMPAADIKIGHAKLPGLLPQRHAEYIAVRFGYDPSFGKPVRTDDRSGLLDELAFVLGKGQYGRIIINGRRTIEEGSVYELRTFNLWNTEDASSLSTLNQRITLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7T4</accession>
    <name>A0A010Z7T4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282727.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_157964_3_1_9"/>
    <dbReference type="OrthoDB" id="2072550at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018680">
        <property type="entry name" value="DUF2164"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09932">
        <property type="entry name" value="DUF2164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="83" mass="9867" checksum="1719EC854D3D27C4" modified="2014-06-11" version="1">MIPIKLPKEQKDEMIKELQNFFYEERGEEIGTIASERLLDHMMHQFAPYIYNQGVRDAKAAVNEKLSQVEDELYALERPINRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7U0</accession>
    <name>A0A010Z7U0_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0299</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282736.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.316"/>
    <dbReference type="HOGENOM" id="CLU_031786_2_0_9"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010964">
        <property type="entry name" value="M20A_pepV-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01887">
        <property type="entry name" value="dipeptidaselike"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="467" mass="51175" checksum="946B68C88244AD46" modified="2014-06-11" version="1">MIDWQKEAESRREDLLRDLDGLLRIESVKDLATASTERPMGHAIGEALHYMLQLTEELGLDVKNVDGYAGHAQYGSFDPNTTIGILGHVDVVPATGAWTSPPFEPAIRAGKLYARGAIDDKGPTIAALYGLKIVKELGLPLTKNVRLIFGTDEESGMSCMRHYVEHEQMPTVGFAPDAEFPMIYAEKGQFNPTLVPKNEAESARSLIALESFESGVRINMVPERAHAVLSGDIRPLVESFEDFCRKHRVKGEAEINAGQAMFTVTGVSAHGSEPEKGVNAGTVLALFLRDAALQPEASHFIGLLNMMHEDFHGEKLGIAFRDEMTGPLTVNPGVIRFGTEEGTQIQLTARCPVQSDHDLIRTQLEATLDRFDFRVSDVQQKGSHHVSKDEAVIRSLQTAYAELTGDEPTLLSTGGATYARFMEKGVAFGACFPGKEMTAHQADEYIEVDDLLKATAIYARAIYELAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWP0</accession>
    <name>A0A010ZWP0_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbfA</name>
        <name evidence="3" type="ORF">SacsacDRAFT_0054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RbfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282268.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.54"/>
    <dbReference type="HOGENOM" id="CLU_089475_6_3_9"/>
    <dbReference type="OrthoDB" id="1971380at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020053">
        <property type="entry name" value="Ribosome-bd_factorA_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01319">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="132" mass="14656" checksum="7539F40F33BDE659" modified="2014-06-11" version="1">MAKIRVGRVGEEIKKELSQMIQSELKDPRIGFVTVTDVEVTGDLSEANVYLSIFGDEDQKQQSLTGIKKATGFLRTEIGKRIRLRHTPTLFFHLDESIAYGSKIESLLGQIKSEDGSEKAKQENKGDGDADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWV2</accession>
    <name>A0A010ZWV2_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent protease subunit HslV</fullName>
            <ecNumber evidence="5">3.4.25.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hslV</name>
        <name evidence="6" type="ORF">SacsacDRAFT_0109</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP-dependent cleavage of peptide bonds with broad specificity.</text>
            <dbReference type="EC" id="3.4.25.2"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Allosterically activated by HslU binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase T1B family. HslV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.2" evidence="5"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282397.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.109"/>
    <dbReference type="HOGENOM" id="CLU_093872_1_1_9"/>
    <dbReference type="OrthoDB" id="1129370at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01913">
        <property type="entry name" value="protease_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00248">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022281">
        <property type="entry name" value="ATP-dep_Prtase_HsIV_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="PTHR32194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039093">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03692">
        <property type="entry name" value="ATP_dep_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0888">Threonine protease</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG83144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="179" mass="19568" checksum="1EC6E1EB501317D9" modified="2014-06-11" version="1">MEISFHATTICAVRKNGKAAIAGDGQVTMGQNVIMKQHAKKVRRLYRGQILAGFAGSVGDAITLFEKFEAKLEEHQGNLQRAAVELVKEWRTDQMLRKLEALMIVMDKDGMLLISGNGEIIEPDDDIIAIGSGGNFALSAARALKRHAEMDAKEIAQASLKIAAEICVYTNDNIIVEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWW3</accession>
    <name>A0A010ZWW3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282417.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.119"/>
    <dbReference type="HOGENOM" id="CLU_391727_0_0_9"/>
    <dbReference type="OrthoDB" id="1446118at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="721" mass="73244" checksum="18F34EFA6817E6C8" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX10</accession>
    <name>A0A010ZX10_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282494.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.160"/>
    <dbReference type="HOGENOM" id="CLU_066192_44_1_9"/>
    <dbReference type="OrthoDB" id="2063007at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="69" mass="8145" checksum="F1274FD52A98270A" modified="2014-06-11" version="1">MQTRIREKRTESDMTQEELSERLNVSRQTIISLEKGKYKPSLILAHKLSQIFNCSIEELFIFEGDENIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX15</accession>
    <name>A0A010ZX15_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">5-methylthioadenosine/S-adenosylhomocysteine deaminase</fullName>
            <shortName evidence="2">MTA/SAH deaminase</shortName>
            <ecNumber evidence="2">3.5.4.28</ecNumber>
            <ecNumber evidence="2">3.5.4.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mtaD</name>
        <name evidence="4" type="ORF">SacsacDRAFT_0164</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + H2O + S-adenosyl-L-homocysteine = NH4(+) + S-inosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:20716"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:57985"/>
            <dbReference type="EC" id="3.5.4.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + H2O + S-methyl-5'-thioadenosine = NH4(+) + S-methyl-5'-thioinosine</text>
            <dbReference type="Rhea" id="RHEA:25025"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:48595"/>
            <dbReference type="EC" id="3.5.4.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.28" evidence="2"/>
    <dbReference type="EC" id="3.5.4.31" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282500.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.166"/>
    <dbReference type="HOGENOM" id="CLU_012358_2_3_9"/>
    <dbReference type="OrthoDB" id="1592010at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090614">
        <property type="term" value="F:5'-methylthioadenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050270">
        <property type="term" value="F:S-adenosylhomocysteine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01281">
        <property type="entry name" value="MTA_SAH_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023512">
        <property type="entry name" value="Deaminase_MtaD/DadD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="3">
        <location>
            <begin position="54"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="441" mass="49171" checksum="373E3EF95D5740C2" modified="2014-06-11" version="1">MGTLLIQGAQLVTMNEAQDVLTGDLLIENNVIARIGTDLSEVQADRVIDARGKVLLPGFIQTHVHLCQTLFRGRADDLELLDWLQQRIWPLEAAHDEESVYYSAMLGIGELISSGTTTLLDMETVHHTDSAFRAMAETGIRAVSGKVMMDHGSEVPKALQEDTAQSLEESVRILEKWNGYDGNRLQYAFCPRFVVSCTEDLLIGVRDLSEHYRVRVHTHASENRGEIEVVENERGMRNIVYLDHLGLAKPNLILAHCVWLDEQEKEIIRERGVKMTHCPGSNLKLASGIAEVPDMLSRHVPVGLGADGAPCNNNLDMFQEMRLAALIQKPIHGPTAMDARTVLRMATMGGAEVLGMEKEIGSLEVGKKADLVLLDLYDFHTFPSNEVDVYSRIVYSATRGNVDTVIIDGKVVMENRLMRTLDRDIVLREADRSIARLVKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX40</accession>
    <name>A0A010ZX40_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">SacsacDRAFT_0184</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506761.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.187"/>
    <dbReference type="HOGENOM" id="CLU_000445_89_26_9"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="367"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG83219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="600" mass="67187" checksum="D3CDF55E6B69C3C0" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX63</accession>
    <name>A0A010ZX63_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nitrate/nitrite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">SacsacDRAFT_0199</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282562.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.206"/>
    <dbReference type="HOGENOM" id="CLU_001265_14_1_9"/>
    <dbReference type="OrthoDB" id="1217595at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17341">
        <property type="entry name" value="MFS_NRT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="10">
        <location>
            <begin position="15"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG83234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="410" mass="43675" checksum="F5C488C1F6C4BC59" modified="2014-06-11" version="1">METEKKSFWKSGHTPTLFSAFLYFDMSFMVWVMLGPLAVVIAADYPMDPMQKAQLVALPILGGSILRLVLGALTDYIGPKLTAQIGMLLTLVPLIIGWQFVQSLDQLYVVAILLGVAGASFAAALPLAGQWYPKEHQGLAMGIAGAGNSGTVLATLFANRIAQHFGSWEVVFGLAIIPISVVFVLFTLFARNSPHRPAPKKLSQYASVLRQGDAWAFCLFYAVTFGGFIGLANYLTIFFNAQYGLSAVRAADFTTLCVIAGSFFRPLGGFLSDRLGGIKMLTFLYGGAGVMFALIATMPPLAMVIVILFVGMMCLGAGNGAVFQLVPQRFGNELGLMTGIVGAAGGLGGYALPMLLGKLYQVTGSYTPGFIGLSVIVLIALGLLTVMQMKWRTTWASAAPIAPLPGRLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXA0</accession>
    <name>A0A010ZXA0_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0219</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282592.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2883227_0_0_9"/>
    <dbReference type="OrthoDB" id="2087577at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="63" mass="7674" checksum="A4F2B1F5B2A67D74" modified="2014-06-11" version="1">MTGRSNHSLWMTEFLLSPDPVKEQRIREVEREDNPELMHSIQFHLALRDQVYLLRRRSRRQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXA4</accession>
    <name>A0A010ZXA4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282606.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056726_1_0_9"/>
    <dbReference type="OrthoDB" id="1878535at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015315">
        <property type="entry name" value="DUF1963"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035948">
        <property type="entry name" value="YwqG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09234">
        <property type="entry name" value="DUF1963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103032">
        <property type="entry name" value="SSF103032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="295" mass="33206" checksum="D37E3138CA7B4740" modified="2014-06-11" version="1">MALSEENRKYLERVIEENDFGHASEYLQRTAKQTIKMSCAGEETYKAIGNSRAAGEPDLPKNTDWPLDSSGTPMTFILQLNLSELAGLDPEHRLPAEGMLFFFAGDYDSVVEHKVLHASSAEMTGAVRKSAPAPTVHEREDGTYLSHRLNARAAIDLPGYAYADNDEIEDEDHEWDEYEELGFALEGDKPFTTVRMFGYAEGQHGDDEYMAALELFGCESTYYPNEAIERLTKAFGGDRERAEREVADIVMLAEIDSDQDIGFQWGDSGVLHYFIRKEDLLNGNFERTTCSFYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXA9</accession>
    <name>A0A010ZXA9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative enzyme involved in biosynthesis of extracellular polysaccharides</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282613.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.240"/>
    <dbReference type="HOGENOM" id="CLU_156590_2_0_9"/>
    <dbReference type="OrthoDB" id="1909149at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="97" mass="11612" checksum="E647B21781E437A7" modified="2014-06-11" version="1">MILEAAMLQVKPGRTEDFERDFRLASAYIGQIEGYLNHELQRCLEDDQKYLLLVRWETLEAHTEGFRGSAQYLEWKRLLHDYYDPFPIVEHFSTVYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXB9</accession>
    <name>A0A010ZXB9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282634.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061789_0_0_9"/>
    <dbReference type="OrthoDB" id="1431378at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="46"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="269" mass="30466" checksum="BE3F1F483D635941" modified="2014-06-11" version="1">MSEFVKTYYNEQAEREWDRLNNPYNAVEMASTLWLIDSYFPREGTVCDIGSGPGRYAIELLKRGYGVTLLELSEKELEIARVKIEEAGLAADGYICENAINMNKLRSESFDAALVMGPLYHLIEREQRLEVLSQTARILKPGGTAILSYINSWGTLKAGVSEFSETFRNPDDLYAYFDEQSLDAERGFTECYFTTPSKAIREIEEAGLELITYAGAEGFLAGLAREVHRLHREDPLVYGNLLRAASETCEAPQYRDATEHLHLVVRRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXG6</accession>
    <name>A0A010ZXG6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282730.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_3_1_9"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="131" mass="15062" checksum="7864861A7AF92AAF" modified="2014-06-11" version="1">MVVIKLHTEKPIPPLQLMRLYQDVDWWPTRTKDGIRKLLAHGVVLGAWEEKQLVGFCRAVSDGVYRAYVEDVVVLRTHRGQGIGRQMMDKMMKELSGIEVVSLFCSAKLADYYHGNGFQETKQTVMHRNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXH1</accession>
    <name>A0A010ZXH1_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">SacsacDRAFT_0300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.317"/>
    <dbReference type="HOGENOM" id="CLU_000445_114_15_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025847">
        <property type="entry name" value="MEDS_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14417">
        <property type="entry name" value="MEDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="212"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="341"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="483"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="731"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="851"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="859"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG83334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="873" mass="97109" checksum="C3645C09A7D4846B" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0M8</accession>
    <name>A0A011A0M8_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0017</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282174.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142273_1_0_9"/>
    <dbReference type="OrthoDB" id="1635052at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08026">
        <property type="entry name" value="DUF326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005560">
        <property type="entry name" value="DUF326"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044543">
        <property type="entry name" value="YHJQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03860">
        <property type="entry name" value="DUF326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="114" mass="12735" checksum="6523EA9F6FA6E4E2" modified="2014-06-11" version="1">MTQLTVTTYKECIDACIRCMNVCNVSYVSSLKGLDIFELRECLRLDRECADLCAVAIQAMTRNSPFVAEICELVAKACDACADECMKHKHEHCQECVEICRECASICRSVLVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0Q1</accession>
    <name>A0A011A0Q1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA segregation ATPase, FtsK/SpoIIIE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">SacsacDRAFT_0042</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.42"/>
    <dbReference type="HOGENOM" id="CLU_001981_9_5_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="8">
        <location>
            <begin position="594"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="231"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="611"/>
            <end position="618"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG83077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="931" mass="99932" checksum="0FBBB17E303558B2" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0R9</accession>
    <name>A0A011A0R9_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zinc metalloprotease</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">SacsacDRAFT_0062</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19268</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282290.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.62"/>
    <dbReference type="HOGENOM" id="CLU_025778_1_0_9"/>
    <dbReference type="OrthoDB" id="1395197at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00054">
        <property type="entry name" value="TIGR00054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="10">
        <location>
            <begin position="188"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG83097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="428" mass="47137" checksum="0352B3406032C0D5" modified="2014-06-11" version="1">MMTLQIVVLTVLMFFVVVTVHEWGHYYFAKRAGILVREFAIGFGPKLFSYKRDETMFTLRLLPLGGYARMAGEDPELDPIQPGQTIAVRLSDEGVVKKIYLDQLDNRRNVVIGEIEWIDIEERMQIRLNVDGETQHLEVDRKADIVTRGQELQVAPKDRQFRSKSVGKRALAIFAGPLMNFVLAFVLFLIYVQVSGVPDEKATGVEVADIVAGTPADSSDLVKGDIIQSIDGQAVNGDLAKVTELVNASGGSEVEMSVQRGSETVQVPVTPKLVDAQDGSQVLQVGIQLSKIKRSASFTETFEFAGKSFANGSTAILDALRKLVFERFDINQLAGPVGTLQATGEIASQGIDQMILWTALVSINLGIFNLLPIPMLDGSRLIFLGIEAVRRRPIDPNKEGMVHFIGFALIFLLMIAVTYNDILRIIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0S4</accession>
    <name>A0A011A0S4_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrH</name>
        <name evidence="8" type="ORF">SacsacDRAFT_0067</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Allosterically activated by GTP. Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.67"/>
    <dbReference type="HOGENOM" id="CLU_033861_0_0_9"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in allosteric activation by GTP" evidence="6">
        <location>
            <begin position="19"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="11"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="134"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="241" mass="25816" checksum="C1ACCF938513FC58" modified="2014-06-11" version="1">MQPAFKRVVLKVSGESLAGQNGYGIDGLMISDIAEQIKEVVELGVEVAVVCGGGNIWRGIAGSASGIDRSTADYMGMLATVMNSLALQDALESIDVPTRVQTSIAMQQIAEPYIRRRAIRHLEKGRVVIFAAGTGNPFFSTDTTAALRAAEIEAEVILMAKNKVDGVYSADPFIDPTAEKFEQLTYMEVISRNLGVMDSTASSLCMDNNIPLIVFAITEQGNIKRVVLGEKIGTIVKGSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0W7</accession>
    <name>A0A011A0W7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA protecting protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282403.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.112"/>
    <dbReference type="HOGENOM" id="CLU_029601_0_3_9"/>
    <dbReference type="OrthoDB" id="1881437at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="375" mass="41350" checksum="8D6B58765FF09E6E" modified="2014-06-11" version="1">MKHEWSPEALWIMALHETTGIGWQSIHTLMRIVWHKGIPFDELFRIPEQTWLALGAQVKLAKAAGNIRLEEARERLGRLRQRGIEPMSYFDEAYPTLMKESAKPPWMLYTIGRRELLKDFSIAIVGTRSPTAYGRVVCERIAGALAENGVCLVSGMARGIDGYSHREALRRGGATIAVLGAGVDVAYPPEHNHLHREIAEQGLIVSESPPGTRPSPGLFPLRNRIIAGLSRGVLIVEAAEKSGSLITGDYALDCGRDVFAVPGPVTSPKSLGTLQLIKNGAKPCADANDILEEYTHLFVPSTPRAAKKEVHEKLTKEERKIYVILEQGDASIDELQRKTSWDFGLLHSVLLSLVIKSQVKSLSGAVYAWIGEPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0X2</accession>
    <name>A0A011A0X2_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0102 protein SacsacDRAFT_0117</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0117</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0102 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115353_2_1_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00048">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003509">
        <property type="entry name" value="UPF0102"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34039">
        <property type="entry name" value="PTHR34039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02021">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00252">
        <property type="entry name" value="TIGR00252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="142" mass="15978" checksum="A2C2100CB42897D8" modified="2014-06-11" version="1">MSESSKTKPSTTVDGSAIHKKIVSPTRKDKGKAAEEAAASYLQQQGWRIIERNWSCRSGELDMIAEQGEILLFVEVRSRSGLGYGMPAESIDARKIQQVRRTAEVYLHRFGISDRPIRFDAVAVMLGRDLEIRSLKHIEDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A103</accession>
    <name>A0A011A103_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endopeptidase La</fullName>
            <ecNumber evidence="1">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0147</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="1"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282476.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.148"/>
    <dbReference type="HOGENOM" id="CLU_042037_2_0_9"/>
    <dbReference type="OrthoDB" id="1324470at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="3">
        <location>
            <begin position="237"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="341" mass="37158" checksum="6BF54DA81A722F38" modified="2014-06-11" version="1">MLRSRLPRIRTLAYLLCLALLVYVVVYMPTSYTIERPGSADDVKPMVRVAGADTDELGTFMMTTVSVTYANLALLGMSLFDDNADIGERNKDQDDDEYRITQQYYMNSSQSSAIAAAYREAGVAFDVETEYVFITTVPDQDPQQKEFVAGDKITEVDGQAVATLEDLRKLLEGRSAGDAVDVSLERGGKTVEQRVKLVDIPNGDGTTRSGFGVSTGEVLRIDPDNPADEVEFTQTRVGGPSAGLMFTLEIYNQLTPGDLTRGYRIAGTGTIKSDGTVGEIGGVQHKIVAAERKGAEVFFVPEGNYDAAKKKLDETGGQMRLVPVKTLEDALNDIQTLPDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A112</accession>
    <name>A0A011A112_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3383637_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="33" mass="3804" checksum="FE0DD988C0D6658A" modified="2014-06-11" version="1">MISNIAENRAKRVTSTRLDKETVGLEDGRKTWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A126</accession>
    <name>A0A011A126_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fumarate hydratase class II</fullName>
            <shortName evidence="3">Fumarase C</shortName>
            <ecNumber evidence="3">4.2.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Aerobic fumarase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Iron-independent fumarase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fumC</name>
        <name evidence="6" type="ORF">SacsacDRAFT_0172</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="3"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282511.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.174"/>
    <dbReference type="HOGENOM" id="CLU_021594_4_1_9"/>
    <dbReference type="OrthoDB" id="734949at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045239">
        <property type="term" value="C:tricarboxylic acid cycle enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="PTHR11444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lyase_1" evidence="4">
        <location>
            <begin position="11"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="5">
        <location>
            <begin position="407"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="97"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding (B site)" evidence="3">
        <location>
            <begin position="128"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="138"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="323"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="3">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG83207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="459" mass="49743" checksum="6C9A052166254738" modified="2014-06-11" version="1">MDYRIEKDTLGEMKVPADKMWGAQTQRSKENFPIGQEKMPSEVIRAFAILKKSAALANHDLGKLSEHKAGAIARAADEILEGLLDEHFPLVVWQTGSGTQSNMNVNEVIAYRGNQMLEGKGGTDERLHPNDDVNMSQSSNDTFPTALHVAGVIAVEDKLLPAIAVLKATLDEKVEAFKDVIKIGRTHLMDATPLTLGQEISGWSAMLEKSGNMIKESVQHMKELAIGGTAVGTGINAHPEFGDRAAAYISQFTQAKFTSAKNKFHALTSHDETVYTHGAIKGLAADLMKIANDVRWLASGPRSGLGEIKIPENEPGSSIMPGKVNPTQPEAITMVVAQVFGNDTTIGFAASQGNFELNVFKPVLIYNFLQSVNLLADSIIAFNDKCAIGIEANLDKIEHNLKNSLMLVTSLNPHIGYENAAKIAKKAHAEGTSLKEAALATGLLTEEEFDRYVDPKKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A140</accession>
    <name>A0A011A140_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-glucosidase-like glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0187</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282538.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.192"/>
    <dbReference type="HOGENOM" id="CLU_004542_5_3_9"/>
    <dbReference type="OrthoDB" id="419160at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="PTHR42721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="SSF50405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Fn3_like" evidence="3">
        <location>
            <begin position="806"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="1027" mass="112480" checksum="1DA27A5FEE7909ED" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A186</accession>
    <name>A0A011A186_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC-type multidrug transport system, ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">SacsacDRAFT_0237</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282620.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.249"/>
    <dbReference type="HOGENOM" id="CLU_000604_84_4_9"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="64"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="380"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="413"/>
            <end position="420"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG83272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="620" mass="68082" checksum="A1EE4BB8C47D373D" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A198</accession>
    <name>A0A011A198_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type antimicrobial peptide transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">SacsacDRAFT_0252</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282642.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_0_9"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="19"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="325"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EXG83287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="418" mass="45253" checksum="5438A45B4E360030" modified="2014-06-11" version="1">MIENLLLSLESLRANKMRSFLTMLGIIIGISSVIAVISVGNAMTSSVTNQFAEFGINNVSIGMQMRAEEMSGEFDTATAKVPKDSDRISNEQIDTMLSRFPEIETLSLSEDAGRGKAKLARKYSNVSITGVNVGYAKANKVKMAEGRYVSDADIKGTRNVIVVSDRTADALYGSNKAAIGNNMIIYTDKAIKQFTIIGVYQYTQPSGMGAMASDKDLETSSYIPVSTAKKDSQYKGYTSLTVVPRTGTDLNVFTDKIIAYLSKLYEKNKEWESYAYNMKSELESTNSMMKTLSLAVAAVASIALIVGGIGVMNIMLVSVTERTHEIGVRKALGAKDAHIRTQFVAEAVVLSVTGGLIGITLGLILGFIGSKLMGADFVLSPYIILGTVLFSMFIGIFFGYYPANKAAKLNPIDALRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A1A1</accession>
    <name>A0A011A1A1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3065956_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="53" mass="5866" checksum="7B9ECAEAC0567788" modified="2014-06-11" version="1">MTDSNQDPNQQSAGEDTLMEKTRKENGANVETQADEWDNKPSPKAAGDEDDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A1A6</accession>
    <name>A0A011A1A6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282661.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098986_0_0_9"/>
    <dbReference type="OrthoDB" id="1892901at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019475">
        <property type="term" value="P:L-lysine catabolic process to acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008567">
        <property type="entry name" value="KCE_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37418">
        <property type="entry name" value="PTHR37418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05853">
        <property type="entry name" value="BKACE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="239" mass="26039" checksum="60847ACC6A418DAB" modified="2014-06-11" version="1">MLQACLNGSRTREDHPAVPYTSEEIASDAEKSVRAGAAELHIHIRDREGKESLAADDVARILSAVRERVPGVPVGISTAWSILPDSAARMQLLRSWHVVPDYVSINIHEPDAEWIIATALSRGINVEAGLCSEADAERFVAMPGCESCLRVLIGIHDPHPGRESSMVRNIRKVLKRAGCTLPILLHGSDATMWPMYIEAMLQGFGGRIGLEDGSMLLSGLAAKDNEELVRTAKLIEGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A1A8</accession>
    <name>A0A011A1A8_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506776.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096795_3_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="176" mass="19606" checksum="82E226AC1CE871D8" modified="2014-06-11" version="1">MNGKELHQTADTKIVVLLLPLKASDIQLLAPIAKRSFDDDSFRHTGVAEDGPHGYADGSLLQALAFEQNLPSYRIEANGILSGAIAVREPEDGIRELELFFVDPDFQGQGVALAAWTTLESMYPHTRLWRLETPGYSLRNHAFYERKCGFARVGIRNPGHPRDESLLFEKSVLGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A1C3</accession>
    <name>A0A011A1C3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylase involved in ubiquinone/menaquinone biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.305"/>
    <dbReference type="HOGENOM" id="CLU_061789_1_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="45"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="267" mass="29738" checksum="658DF503C7EBEC5F" modified="2014-06-11" version="1">MEKVIGYYEGYDEGNRLGRDRVRQLEFATTTHVLEPYLQSVENLLDIGAGTGAYAFYYAARGVRVTAADVTPGHVDAMRKRIAKERISGMTAELADATDLSRYADESFDTVLCLGPLYHLRTAENRQNCLKECMRVLKPGGVLATAYINRFFIAEYLIASGAKKPEAPWLSRVAEQGTFGADERDPFLSAAYFHTPGEAETELRFAGFDVREHVAVEGNGFVISDAVGKMSEEQYRIWTEHHFLVCREPSRLGSSNHGLIVARKTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A1C9</accession>
    <name>A0A011A1C9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">L-asparaginase II</fullName>
            <ecNumber evidence="1">3.5.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282733.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.315"/>
    <dbReference type="HOGENOM" id="CLU_062004_0_0_9"/>
    <dbReference type="OrthoDB" id="1434447at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010349">
        <property type="entry name" value="Asparaginase_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42110">
        <property type="entry name" value="PTHR42110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06089">
        <property type="entry name" value="Asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="337" mass="36992" checksum="235726E1CD5239D2" modified="2014-06-11" version="1">MSQDVQVTRGRYVESNHEIHVAVVDNKGRLLYAAGDPDRLTFPRSSMKPFQAVPLIESGAADAFGYGDAEISLSCASHSGEPIHRHAVLDVLSRAHLSEDDLQCGTHIPRDGESYRELIREGRELTPVFSNCSGKHSGMLLTAVHLNEDTQTYREIEHPHQQRILSVIADVCDFPAAEIGIGVDGCGVPVHRLPLRYAALGFARLAKPEGKVSEQRADALNRVRRGMTRRPEMVAGKNRFDTDLMRVFQGNLVAKVGAEGVQCIGVADRGIGIAVKVEDGSERATSVAAMEVLKQLGIGTDRQFAELADYVHVPVLNARRERIGEVKPNFVLRNMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM70</accession>
    <name>A0A011AM70_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0234 protein SacsacDRAFT_0036</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0234 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282220.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.36"/>
    <dbReference type="HOGENOM" id="CLU_099839_1_0_9"/>
    <dbReference type="OrthoDB" id="1612988at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11740">
        <property type="entry name" value="YajQ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00632">
        <property type="entry name" value="UPF0234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007551">
        <property type="entry name" value="DUF520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035571">
        <property type="entry name" value="UPF0234-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035570">
        <property type="entry name" value="UPF0234_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036183">
        <property type="entry name" value="YajQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30476">
        <property type="entry name" value="PTHR30476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04461">
        <property type="entry name" value="DUF520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89963">
        <property type="entry name" value="SSF89963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="163" mass="18516" checksum="82731176EE4C422B" modified="2014-06-11" version="1">MASESSMDIVSKMDMQELKNAIDQAEREITSRFDFKNTKTSFELEKDSLTIISDDEYKLGAVIDILQSKMIKRGVPFKNLDFGKVESASLNTVRQKMGLKSGIESDNSKKINTLIRDSKLKVKSQIQGDQIRVTSKSRDDLQAVMKLLREADLSIELQFTNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM74</accession>
    <name>A0A011AM74_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative Zn-dependent peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.41"/>
    <dbReference type="HOGENOM" id="CLU_052943_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16_C" evidence="1">
        <location>
            <begin position="185"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="429" mass="47873" checksum="40F32B5B0A5DF37E" modified="2014-06-11" version="1">MMSTPGFERAAEGRIRIHVLPTKSFKTFAVSLYAGAPLQEETVTPIALTPFVLRRGNASYPETILFRERLEELYGAGFGFDVYKRDGSQIVQFRMDTINDAFVSTDEPLLESSLAFLGETLTRPALENGVFKPKFVDAERDNVRKKLDAIINNKARYAGVRCVEEMFAGESYRLNALGKREALENLDAAVLHDSYRKWLSEASLDLYVVGDTTLDEVRSIVHKHFDVAGPGHSPYTYAGSEKNEGVGNPHIVKEVMDVSQGKLNIGFKTSIDYADDRYAAALVYNGVLGGYPHSKLFQNVREKASLAYYASSQYEPHKAFGTIQSGIEIGNYDRALDIIRVQLDAMKAGEITETELSQTQAMLGNDLREIRDSAFQMIHHDFGGRLSGRERAVSELIEQVESMTTQQVAEAAQNFRLDTIYFLTGKEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM86</accession>
    <name>A0A011AM86_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal protein HS6-type (S12/L30/L7a)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282273.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.56"/>
    <dbReference type="HOGENOM" id="CLU_157804_0_0_9"/>
    <dbReference type="OrthoDB" id="2066583at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_L7Ae/L30e/S12e/Gad45"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L7Ae" evidence="1">
        <location>
            <begin position="8"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="107" mass="11691" checksum="F778DBEF5F02908A" modified="2014-06-11" version="1">MNNELSGLGLAMRAGKMVTGDEMVIKAIRSREAKLVVLAGDASSNTQKKFRDKCASYGIPLLVGFDRERLGASIGKPERLVLALTEQGFADMIRRKLGTTSEVEYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMA1</accession>
    <name>A0A011AMA1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282314.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1426747_0_0_9"/>
    <dbReference type="OrthoDB" id="2007179at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="188" mass="21174" checksum="F0AA68B984FC6909" modified="2014-06-11" version="1">MNDAWLYVMLLGAAAVVYAFLIPKEKSAKQASGSDRVVQQVEQTLEQYMVEMEKENDDLVNLLVQIRQETGAKQLALQEQLGDMRGRLAEMERTAGKHEARIEQLSSVDPRAAQEAAIQLRNELLENAATLSPSPEPQPEPEDSVRHRYPQLFELHDQGKSVDFIAKAIGLQRGEIQLILRLAKREEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMA5</accession>
    <name>A0A011AMA5_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable chemoreceptor glutamine deamidase CheD</fullName>
            <ecNumber evidence="3">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cheD</name>
        <name evidence="4" type="ORF">SacsacDRAFT_0076</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CheD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.44" evidence="3"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282326.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.77"/>
    <dbReference type="HOGENOM" id="CLU_087854_2_0_9"/>
    <dbReference type="OrthoDB" id="1863047at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16352">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01440">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038592">
        <property type="entry name" value="CheD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005659">
        <property type="entry name" value="Chemorcpt_Glu_NH3ase_CheD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35147">
        <property type="entry name" value="PTHR35147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03975">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="165" mass="17507" checksum="A6C9D19B352FED4A" modified="2014-06-11" version="1">MTDEKNLVKVGMADLNVVGNSGILRTTGLGSCVGLTLYDPQIKVAGMAHVMLPSSDIARESQINVAKYADTALPVLVDKLVDLGASKRRLVAKMAGGAQMFAFAGSGDTMRIGPRNVESCKEMLKKLGISLYSEDTGANYGRTIEISSETGILTIRSVQKGVKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMB5</accession>
    <name>A0A011AMB5_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Flagellar biosynthetic protein FliQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fliQ</name>
        <name evidence="10" type="ORF">SacsacDRAFT_0086</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Role in flagellar biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the FliQ/MopD/SpaQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282349.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.87"/>
    <dbReference type="HOGENOM" id="CLU_164516_2_1_9"/>
    <dbReference type="OrthoDB" id="1939288at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002191">
        <property type="entry name" value="Bac_export_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006305">
        <property type="entry name" value="FliQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34040">
        <property type="entry name" value="PTHR34040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01313">
        <property type="entry name" value="Bac_export_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004669">
        <property type="entry name" value="FliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00952">
        <property type="entry name" value="TYPE3IMQPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01402">
        <property type="entry name" value="fliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG83121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="89" mass="9766" checksum="29DA7B33B18CCB41" modified="2014-06-11" version="1">MDSNFIIGLAGQAIYVVLKASAPMLILALVVGLIVSVFQATTQIQEQTLAFVPKIVAVMFSVLIFGPWILNTLVDFTYNILNNLYLYIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMF2</accession>
    <name>A0A011AMF2_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Ribosome biogenesis GTPase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">SacsacDRAFT_0121</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282419.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.121"/>
    <dbReference type="HOGENOM" id="CLU_011106_1_0_9"/>
    <dbReference type="OrthoDB" id="1083771at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019991">
        <property type="entry name" value="GTP-bd_ribosome_bgen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016478">
        <property type="entry name" value="GTPase_MTG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006230">
        <property type="entry name" value="MG442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03596">
        <property type="entry name" value="GTPase_YlqF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="4">
        <location>
            <begin position="13"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="58"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="130"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006230-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG83156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="287" mass="32377" checksum="AC790B81D91FB3B1" modified="2014-06-11" version="1">MTIQWFPGHMTRARRQIEAKLGLIDLAIELLDARLPLSSRNPMIGDILKDKPRLILLNKSDLADPEVTKRWIEYFREEGHLAIETDTPGGRGVKDISVYAKQLLKEKIDRQIAKGMNPRAIRGLIVGIPNVGKSTLINKLAGKSIAETGDRPGVTKGQQWIKIGKEMELLDTPGILWPKFDDQNVGMKLAVTGAIKEDVLNVEEVTFFAIKYCAEHYWDRLSERYALGERPTVFDDPDEIVHIMEEIGRKRGCIMSGGRVDLTKASVLFLRDLRSGKLGRFSLEEPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMF8</accession>
    <name>A0A011AMF8_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rimM</name>
        <name evidence="7" type="ORF">SacsacDRAFT_0126</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RimM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282432.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.126"/>
    <dbReference type="HOGENOM" id="CLU_077636_3_1_9"/>
    <dbReference type="OrthoDB" id="1497415at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RimM" evidence="5">
        <location>
            <begin position="13"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="PRC" evidence="6">
        <location>
            <begin position="104"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="178" mass="19939" checksum="6B354B850B007BF8" modified="2014-06-11" version="1">MTNSNTQQDFLSVGKVANTHGVRGELKVFPFTDFPELRFAQGKELLLISPEDGKALKVKVVSAREQKTVYIVKLEGYDNINQVEKYKGWEIKVPKEEAVAAEDNAYYFHEIIGCTVLSEEGEELGIITDILTPGANDVWVVKRKGGKELLIPFIESVVKEVNVAEKKVRIEVMEGLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMG4</accession>
    <name>A0A011AMG4_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282445.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.131"/>
    <dbReference type="HOGENOM" id="CLU_029266_0_0_9"/>
    <dbReference type="OrthoDB" id="1757195at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011483">
        <property type="entry name" value="DUF1593"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07632">
        <property type="entry name" value="DUF1593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458424" description="DUF1593 domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1593" evidence="2">
        <location>
            <begin position="56"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="541" mass="61421" checksum="7996858558E94F7B" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMH0</accession>
    <name>A0A011AMH0_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 12">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">SacsacDRAFT_0136</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12 14">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 12"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282456.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.137"/>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_9"/>
    <dbReference type="OrthoDB" id="606297at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="15">
        <location>
            <begin position="7"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXG83171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="414" mass="43785" checksum="D9B9583F5F7F7040" modified="2014-06-11" version="1">MEQQHRVVVTGMGVVTSLGKDVETFWNSLLAGKSGISKIESFDVSEYPTQIAAEIHDFNPEDYVERKEARKMDRYVQFAYAASTQALQDSGLKIGDSIEAERIGVIVGSGIGGLGTWEDQFTILMQKGPKRVSPFFIPMMIANMGSGDVSIKLGAKGPNTSVVTACATGTHSIGDSFKLIARGDADAMICGGAEATIRPTGLAGFCAMRAMSTRNDDPTQASRPFDKDRDGFVMGEGAGVFVLESLEHAQARGAHIYAEVVGYGLSADAHHMTDPDPDGAARCMTMALKSASLQPEDLDYINAHGTSTPAGDKSETTAVKKALGEHASKVAVSSTKSMTGHLLGAAGGVEAVICALSLEHQIMAPTINIDNQDEACDLDYVPNVARKANLNVVMSNSFGFGGHNASVILKKFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMH6</accession>
    <name>A0A011AMH6_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphate acyltransferase</fullName>
            <ecNumber evidence="3 4">2.3.1.274</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Acyl-ACP phosphotransacylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Acyl-[acyl-carrier-protein]--phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phosphate-acyl-ACP acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">plsX</name>
        <name evidence="6" type="ORF">SacsacDRAFT_0141</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>a fatty acyl-[ACP] + phosphate = an acyl phosphate + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.274"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Probably interacts with PlsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Associated with the membrane possibly through PlsY.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PlsX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.274" evidence="3 4"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.142"/>
    <dbReference type="HOGENOM" id="CLU_039379_1_1_9"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043811">
        <property type="term" value="F:phosphate:acyl-[acyl carrier protein] acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00019">
        <property type="entry name" value="PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003664">
        <property type="entry name" value="FA_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012281">
        <property type="entry name" value="Phospholipid_synth_PlsX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30100">
        <property type="entry name" value="PTHR30100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02504">
        <property type="entry name" value="FA_synthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002465">
        <property type="entry name" value="Phsphlp_syn_PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00182">
        <property type="entry name" value="plsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG83176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="358" mass="37593" checksum="2F1A5B192879063D" modified="2014-06-11" version="1">MIIAIDAMGGDHAPDSAAAGALQAAAEWSDITIKLVGDEAKLAPLIGEGKPNLQIVHAGEVISGDDEPVRAVRRKKDASMVVAGRMVKEGEADAMISAGNTGALMTTGLLVVGRMNGVERPALAPMIPTLDESGQGTLALDLGANMDAKPEHLAQYALMGSLYREKVHGITNPRVGLLNVGTEPGKGNELTKAAFPLISELPVNFVGNVEARDILDGVCDVLVCDGFAGNILLKALEGTAGAVFKLLKQELTSSFKAKIGAALVMPQLRGLRSKMDYKEHGGAPLLGLNGLVIKAHGSSDAEAIKNAVRQAKIALESQLVSSISSSMQIMVREQKQTDEQDAAYEQENEQISGKRVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMJ6</accession>
    <name>A0A011AMJ6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Small GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0161</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.162"/>
    <dbReference type="HOGENOM" id="CLU_002794_5_1_9"/>
    <dbReference type="OrthoDB" id="466142at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03711">
        <property type="entry name" value="Tet_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035650">
        <property type="entry name" value="Tet_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="5"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="672" mass="73893" checksum="FEC8A43D760A5B2A" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMK1</accession>
    <name>A0A011AMK1_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">SacsacDRAFT_0166</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506757.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.168"/>
    <dbReference type="HOGENOM" id="CLU_000445_104_15_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="78"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="320"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="13">
        <location>
            <begin position="464"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="9">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="8">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG83201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="558" mass="61882" checksum="4E054ADBE0C9EF64" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMM0</accession>
    <name>A0A011AMM0_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zn-dependent hydrolase, glyoxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282536.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.191"/>
    <dbReference type="HOGENOM" id="CLU_030571_2_4_9"/>
    <dbReference type="OrthoDB" id="733552at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="20"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="214"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="242" mass="26686" checksum="8BD9EEE61786F0FA" modified="2014-06-11" version="1">MGVKSITESIRSVGVWVGLPIQVWIVAEQDGVTLVDTGMSFMTKGILKAIERMDAGPLKQILLTHGHSDHVGGLQNILRVHDVPVYMHATEIPYAEGEKAYPGKDKAHVHVEKGILQPLPFVQGKSKELAAHGSLTPYWTPGHSPGHVVYFHQGENVLLAGDLFNGKRGKLIQPRFTPDPELAMRSAFAIVRELDPERIEVCHGSTVYRPAGKLDDMEAEILRARELEAKLKARKDAKAKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMM5</accession>
    <name>A0A011AMM5_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">SacsacDRAFT_0191</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282544.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060077_0_6_9"/>
    <dbReference type="OrthoDB" id="1467120at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036244">
        <property type="entry name" value="TipA-like_antibiotic-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012925">
        <property type="entry name" value="TipAS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07739">
        <property type="entry name" value="TipAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89082">
        <property type="entry name" value="SSF89082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="5">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG83226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="257" mass="29900" checksum="DA1AE3B1FDCB6DE0" modified="2014-06-11" version="1">MPKALLTVHEVVNITGTTARTLHHYDRIGLLKPAKVKENGYRLYDRANLERLQIILFLKETGLRLEDIAVVLELPEPERRQALHKHREQLIDKKRRLEGILHDFDRYLEAGTIFGPRSPEMPGLPLHEQYDREAELVYGDTQAYAVYKQRMQQLEQRPPGEREMQLQQVEQRMNGVFAELFVLMRNAPESPDIQLKIKEWADELAAYTEITPQLLIHIAENYRGDNRFQAYFDTFGGEKGKFASFLHQAILAYSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMN7</accession>
    <name>A0A011AMN7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sugar kinase, ribokinase</fullName>
            <ecNumber evidence="4">2.7.1.92</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0201</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.92" evidence="4"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282568.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.208"/>
    <dbReference type="HOGENOM" id="CLU_027634_6_0_9"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047590">
        <property type="term" value="F:5-dehydro-2-deoxygluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="8"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="330" mass="35845" checksum="9A0FDC50975F6E43" modified="2014-06-11" version="1">MQDNRVDMVTLGESMILFQSYNQGALQYEPLFTKSLAGAESNVAIGLSRLGKKTRWVGRLGSDPFGDLVLTTLSGQGVDVSHAVRDHEAPTAVYFKDFKRYGDPAVYYYRKGSAASRLSPEMVDEAWLEGAGHLHVTGITPALGDHTAAATRKLMEMARKKGLTVSFDPNLRRKLWSEETARETLLSLIPLCDIFMPGDEEAEFLLGKLEIEAYGEAFLNMGPKLVAMKLGAEGSIGFTEKASVRAEPFAVDRLIDTVGAGDAFASGLLSVLLDHREKIADGLGEAALHEALRRANLLGSMATQFKGDWEGLPTLAEVHGILDGEKSVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMQ9</accession>
    <name>A0A011AMQ9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282581.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1538967_0_0_9"/>
    <dbReference type="OrthoDB" id="1932699at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="174" mass="19992" checksum="DF30A061D956A4EE" modified="2014-06-11" version="1">MNIKEWVEAAQRGEVTEDDVQQALWLLSNTPLLYDTGETVAVEDYMRGLERQPSAAETEAYGELFDLAVALSRRYAEAEAYDRMQDVLSLQFDLWARGVLRLEDWIAWLQGAVQGRIDLPVYDFDEVLGSAPEEFMIQDFHDELNFRLEDAPEDEWALSHLDELYRKVGVTGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMT6</accession>
    <name>A0A011AMT6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative nucleoside-diphosphate sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282628.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.253"/>
    <dbReference type="HOGENOM" id="CLU_569777_0_0_9"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="2">
        <location>
            <begin position="17"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="510" mass="57498" checksum="F26652D11A57E6E4" modified="2014-06-11" version="1">MDKETNDQQRPKVILTGASGYIGHNLMQKLIEDYDVIALSRHGDSHEDEEHVEWRSCDFYSMDDAQESLQGADYAFYLIHSMMPTAKLTQGDFEDMDAILADHFARAARKNGVKQIVYLSGIVPDDVPEEELSRHLRSRLEVQRILESSGVPVTTIRAGLIVGPQGSSFPILYKLVQRLPIMTLPTWTRTKTHAVALDDVLNSLKNSLGNEDVKGRAVDVGGPDVMSYKEMMQQMAEVLEVKRRFIDLPLLTVNLSRLWVTLVTGAPREMAYPLIESLIHPMVAHSDLKVEGISDGKITFKQAARDSLEEEKKKQEDAERKQRESSRNEESKPTQSEEKVAKADVRSVQRVTLPEGKDARWAGEYYIQWLGKAMLRPFIRTETGEDGVSRIYIRFFSKPILELSYDASRSSHDRAVYRITGGMFANAKDAHHGRLEFLMIPGSSDCVVAIHDYMPSMPWFLYKYTQAKLHLVVMYAFRKHLERKGSLGKSSTSKKAGGSVGTPSSLEAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMV7</accession>
    <name>A0A011AMV7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alkaline phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0272</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282683.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.289"/>
    <dbReference type="HOGENOM" id="CLU_008539_6_2_9"/>
    <dbReference type="OrthoDB" id="585847at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="PTHR11596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459617" evidence="7">
        <location>
            <begin position="34"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="459" mass="48730" checksum="5E3C2BEFE6BA913C" modified="2014-06-11" version="1">MNRLLKKGLPAVLGLTLAATPAWIGATTPTAPAAPTATQAQADGTVKNVIFLIGDGMGPSYTAAYRYMIDKASTPTMEKTVFDPYLVGMQTTYSEDEHQNITDSASAATAMSAAVKTYNAAIAVDNDQTEVKTVLEQAKENGMSTGLVATSEITHATPAAYGAHDISRKNMDAIADDYFDEMIGGQHKIDVLLGGGKSNFARKDRDLTAEFKKAGFGYVTDRKGLLANKDEQLLGLFADGGLDKMIDRTSATPSLKEMTNAALDRLSDNDKGFFLMVEGSQIDWAGHDNDIVGAMSEMEDFAGAFQAAIDFAKKDGNTLVVATADHSTGGLSLGANGEYNFNVAPIKAAVHTPDYMAAKITAGESVDKVLLQNIKLKLTAAERASVKKAAESKDATTIDNAIEAIFNTRSFTGWTTGGHTGEDVPVYAYGPSSERFAGLIDNTDNAKIIFELLSGKPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMW2</accession>
    <name>A0A011AMW2_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282689.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1093466_0_0_9"/>
    <dbReference type="OrthoDB" id="1480086at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="255" mass="29075" checksum="A13639FE7C588BFB" modified="2014-06-11" version="1">MLNLLKMDAYRFIRNKTMYMLLLLFCAFQIFGIFMMRQYSQEMEAGGGVAVGSLDASEFIQYTLSQPPSWMLLYITVFVVYFYMSEYQSGFGKNYMSMRRARIYTILAKIWISALFVGLLFLTMLVSDWIGRGLFFDNTTWGDTGYFVKLLIGQFLLHWAFAILMLCITVLCKNLLAGVIIGFVLALNIPGMLLGALESLVNGVNISQYWLVNTLVAVKDFNDAGEFMQTLLVAFVFIVVFAAIAVRHKIREDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMW5</accession>
    <name>A0A011AMW5_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Threonine synthase</fullName>
            <ecNumber evidence="5">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">SacsacDRAFT_0282</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-homoserine = L-threonine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.2.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="5"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282699.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.299"/>
    <dbReference type="HOGENOM" id="CLU_015170_1_0_9"/>
    <dbReference type="OrthoDB" id="428821at2"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Thr_synth_N" evidence="11">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="PALP" evidence="10">
        <location>
            <begin position="89"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG83316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="472" mass="52947" checksum="7CB98ADF503C4C06" modified="2014-06-11" version="1">MNYISTRGQVEPKGFIDTVLMGLGEDGGLMVPEQIPTVSAETLDRWKTLPFRELFIEIFSLYANDEIPQEDLKQLVDASYATFRDPEVTPVRKLNDSLYILELFHGPTFAFKDVALQFMGEFYSYVSKTRGEIIHILGATSGDTGAAAIQGVRGKEGIKICILHPHGKVSKVQELQMTTVNDENVLNLSVHGNFDDCQRIIKELFSDLEFKSKHHLRAINSINFVRILAQTVYYFYAYFQAEKQVGDDSKKINVSVPSGNFGNIFSGFLAKKMGLPINKLIIATNENNILERFVTTGEYQPGEFRKTHSPSMDIQVASNFERYLYYLLDEDAVEVSKYMQQLAEGRKIVVEGELLQRVQSELHALGATNEQNLQLIGKYRSETGYLLDPHTACGVAASEAFTEEGEVTVSFATAHPAKFDEAIRLLDITQEFPVEIAELIAKDQYQTVIDNDKAEVTRQLEAFFAGGKVSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMX3</accession>
    <name>A0A011AMX3_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">msrA</name>
        <name evidence="7" type="ORF">SacsacDRAFT_0297</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.314"/>
    <dbReference type="HOGENOM" id="CLU_031040_10_1_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="6">
        <location>
            <begin position="9"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="178" mass="20542" checksum="75CBD3175DF9C4CF" modified="2014-06-11" version="1">MTEKKNIQQATFAGGCFWCMVTPFEEMPGIHGIVSGYMGGTVDNPTYEQVKTGTTGHYEVVQITFEPDVFPYERLLELYWPQTDPTDGEGQFQDRGTQYKPAIFFHNEAQQEAALATRQELADSGRFDKPIVTEVLPAQIFYEAEDYHQDYHKKNPKHYKEDRQQSGRDEFIDANWQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS64</accession>
    <name>A0A010YS64_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506748.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072307_0_0_9"/>
    <dbReference type="OrthoDB" id="1507232at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001119">
        <property type="entry name" value="SLH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00395">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51272">
        <property type="entry name" value="SLH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLH" evidence="2">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="SLH" evidence="2">
        <location>
            <begin position="143"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="311" mass="33130" checksum="D1B0BDB64612568E" modified="2014-06-11" version="1">MKKTVKACAALVMAGSFAFAASASAYSDISNEDNAKIAQSLQQMGVMKGIGQDLFAPSVDLTNAQAVQLIVNAFGLETDPGVDYIPVPSFNNDAWYAPAYEAALHNGIKTVTKTDSVSEKMTREQFASLLLEGINTTGQYPTTKMYIFFDDEKEFTGDHLGAIQTLGNMRIISPGGEFRPQDPITRMEAAELVYNAIEFIDKVGGNADNAGEGTEVTEVSVTTAKEADGRVKATLKASLPNPGYGLKIDDVKYDGGKATIQYSITKPEAGMMYPQVITDAEVSTYLTGTPSEVVAEQTGGETGASDAKLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YS97</accession>
    <name>A0A010YS97_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aspartokinase</fullName>
            <ecNumber evidence="12">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">SacsacDRAFT_0045</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the aspartokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="12"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282248.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.45"/>
    <dbReference type="HOGENOM" id="CLU_009116_3_2_9"/>
    <dbReference type="OrthoDB" id="1067792at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00656">
        <property type="entry name" value="asp_kin_monofn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="7 12 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="14">
        <location>
            <begin position="4"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="ACT_7" evidence="15">
        <location>
            <begin position="340"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="179"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="215"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000726-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXG83080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="406" mass="43369" checksum="931D8EE4E507E0D5" modified="2014-06-11" version="1">MAIRVQKFGGTSLSSEEARAHVVRHVQRELAAGYQLVVVVSAMGRSGDPYATDTLLGWAASTSGKSLPAKEKDLLMGCGEIISAATLCGILHQEGIDATVLTGAQAGFMTDSHFGNARILEMRPERILRELQDHSVVIVTGFQGQNEYGDLTTLGRGGSDTSATALGAALHAEIVDIYTDVNGILTADPRLVEDAKPLEVVSYTEICNMAYQGAKVIHPRAVEIAMQAQIPVRVRSTFSEEEGTLVTHPENFADVSAGVIDRFVTGIAYVNGVTQITVEQPDPSGQLSLNVFKAMAENAISVDFINVTPVGAVYTVFDSEAERALTALRGIGYEPRALNGCAKVSVIGGGINGVPGIMSHIVEALTLQNVQILQSADSNTTIWVLVKKDDMVKALKALHTRFELHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSA3</accession>
    <name>A0A010YSA3_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsO</name>
        <name evidence="8" type="ORF">SacsacDRAFT_0050</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="3 6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282261.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.50"/>
    <dbReference type="HOGENOM" id="CLU_148518_0_0_9"/>
    <dbReference type="OrthoDB" id="1990141at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="89" mass="10504" checksum="8A5F7E9D2917BDDF" modified="2014-06-11" version="1">MALTQERKNQLIEEHRTHESDTGSPEVQVAILTENIVNLTDHLRTHKKDHHSRRGLLKMVGQRRRLLAYLKNNDVRRYSALIEKLGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSD0</accession>
    <name>A0A010YSD0_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282324.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.76"/>
    <dbReference type="HOGENOM" id="CLU_149313_0_0_9"/>
    <dbReference type="OrthoDB" id="1909324at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="153" mass="16683" checksum="F7997905A16E8BBA" modified="2014-06-11" version="1">MKGTIRVNLIFALIGFVITFLFAVRTNLPVTSLIRGGIGAAVWFLLAFLFRVVLGALEPLPKDKEGSGSSEPGAALDDDVRGARLDLVTPDESDQLNDLLKPDADKARVTEERTGQMDDFQPLNPPKLVSTKEKDPEELAKAVRHLTEDEGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSE2</accession>
    <name>A0A010YSE2_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Flagellar biosynthetic protein FliR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">SacsacDRAFT_0085</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Role in flagellar biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the FliR/MopE/SpaR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.86"/>
    <dbReference type="HOGENOM" id="CLU_063626_2_3_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006303">
        <property type="entry name" value="FliR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002010">
        <property type="entry name" value="T3SS_IM_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30065">
        <property type="entry name" value="PTHR30065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01311">
        <property type="entry name" value="Bac_export_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00953">
        <property type="entry name" value="TYPE3IMRPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01400">
        <property type="entry name" value="fliR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="171"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG83120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="266" mass="29068" checksum="66C12318E73B1D39" modified="2014-06-11" version="1">MMTTLMQAFPVFLLMFCRITSFFVVAPLISSRNVPTRFKVGLATIVALLVYLSYGVNQTAAFDGSYVLLIVREILIGLMLGYVANLILVSIQIAGAILDIQMGFGMATVFDPTSGMVTPLTGQFKYMIAMLLFLAMNGHHRLLDAIVYSYNWVPIDNRLFTEISNGNLMEFFLKAFAAAMVIAFQMAAPIVVALFLTDVGLGFLAKTAPQFNIFVIGIPIKIIVGLILLLLLMPSLTYIFDNLFSLMAETMQGFLGTVGERPGSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSE9</accession>
    <name>A0A010YSE9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Flagellar motor switch protein FliN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">SacsacDRAFT_0090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282357.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.91"/>
    <dbReference type="HOGENOM" id="CLU_033893_0_0_9"/>
    <dbReference type="OrthoDB" id="1875967at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007597">
        <property type="entry name" value="CheC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012826">
        <property type="entry name" value="FliN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001172">
        <property type="entry name" value="FliN_T3SS_HrcQb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04509">
        <property type="entry name" value="CheC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00956">
        <property type="entry name" value="FLGMOTORFLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02480">
        <property type="entry name" value="fliN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheC" evidence="9">
        <location>
            <begin position="43"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="CheC" evidence="9">
        <location>
            <begin position="139"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="FliMN_C" evidence="8">
        <location>
            <begin position="368"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="230"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="242"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="258"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG83125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="447" mass="48353" checksum="627ECFC5B950A30F" modified="2014-06-11" version="1">MTSKDYLSQEEIDALLKQSESDDGGLSSAGAEETVDDFLTPLEQDALGEIGNITFGSAATALSTLLGRKVDITTPKVSIITRSQFESEFPKPHVAIHVNYVDGFQGINSLVIKTRDAQIIADLMLGGEGDPQDEELNEIHISAVQEAMNQMMGSSATSMSTIFNRFVNISPPAIDILDVSSGDGVSNLPAEETLIKVSFRLLIGDLIDSTLMQLITVDFAKNMVDMLLGGGMTEEEPPAPQPQVAAAQPPVQTPAPEPQVQQQPQVQNTPYQDPYAASAGQQQQQPGMPPYGAPMQQQPPYPGYGAPGMQPDYGMQYPAYGQMPMQQQPPQPNHYGNAGRNVNVQPVQFGNLQNGGYGQADENNLGLLMDIPLKVTVELGRTQKQIKDILELSQGSIVELDKLAGEPVDILVNNKLIAKGEVVVIDENFGVRVTDIVSQWDRIQNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSH7</accession>
    <name>A0A010YSH7_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO</fullName>
            <ecNumber evidence="10">2.1.1.74</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Folate-dependent tRNA (uracil-5-)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Folate-dependent tRNA(M-5-U54)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">trmFO</name>
        <name evidence="12" type="ORF">SacsacDRAFT_0110</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH + uridine(54) in tRNA = (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:16873"/>
            <dbReference type="Rhea" id="RHEA-COMP:10167"/>
            <dbReference type="Rhea" id="RHEA-COMP:10193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
            <dbReference type="EC" id="2.1.1.74"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH + uridine(54) in tRNA = (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:62372"/>
            <dbReference type="Rhea" id="RHEA-COMP:10167"/>
            <dbReference type="Rhea" id="RHEA-COMP:10193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
            <dbReference type="EC" id="2.1.1.74"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MnmG family. TrmFO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.74" evidence="10"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282399.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.110"/>
    <dbReference type="HOGENOM" id="CLU_033057_1_0_9"/>
    <dbReference type="OrthoDB" id="516534at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030698">
        <property type="term" value="F:5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047151">
        <property type="term" value="F:methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01037">
        <property type="entry name" value="TrmFO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004417">
        <property type="entry name" value="TrmFO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF2">
        <property type="entry name" value="PTHR11806:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00137">
        <property type="entry name" value="gid_trmFO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 10 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0520">NAD</keyword>
    <keyword evidence="8 10" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="11">
        <location>
            <begin position="12"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG83145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="449" mass="49556" checksum="E81A94AB26D06AB2" modified="2014-06-11" version="1">MSNNESSNTQRVTVIGAGLAGSEAAWQIASRGVPVTLYEMRPKVKTPAHHTSYFAELVCSNSLRANGFTGAVGVLKEEMRRLDSLVIGKADASAVPAGGALAVDRDLFSGGITQALKEHPLVDVREEEVTEIPEDGITVIATGPLTSPALSAQIKSFMGEEYFYFYDAAAPIIEKDSIDMDKVYLASRYDKGEAAYLNCPMTEEEFDRFYEALITAEKAELKEFEKEIYFEGCMPIEVMMQRGRQTALFGPMKPVGLPDPRTGKIPFAVVQLRQDNAAGTLYNLVGFQTHLKWGEQKRVFQMIPGLENVDIVRYGVMHRNTFINSPRLLEPTYQCKARPNLFFAGQMTGVEGYVESAASGLIAGINAAHQALGREPIVFPEETTLGGMARYITEADPEHFQPMNANFGLLPKPEKKIRNKKEKNEALAMRALDKLAAFTEEHSLNAVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSI4</accession>
    <name>A0A010YSI4_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282409.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.115"/>
    <dbReference type="HOGENOM" id="CLU_083287_3_0_9"/>
    <dbReference type="OrthoDB" id="1626703at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="155" mass="17799" checksum="7E499DE66C7FE66C" modified="2014-06-11" version="1">MGKVNEYPQLQLDNMLCFSIYASSREITKMYQPYLEQLGVTYSQYLVLIVLWEQDERTVKELGEELFLDSGTLTPLLKRLEAAGLVERNRSTEDERKVFISLTKKGRALQDQAAHIPECMARDLRMDVPEFVELLGRFQNLLARAHDVNVSSSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSJ8</accession>
    <name>A0A010YSJ8_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">trmD</name>
        <name evidence="17" type="ORF">SacsacDRAFT_0125</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 15">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="6 13 15"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.125"/>
    <dbReference type="HOGENOM" id="CLU_047363_0_1_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="16">
        <location>
            <begin position="27"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="153"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EXG83160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="269" mass="30285" checksum="F52112A4BE51ABD5" modified="2014-06-11" version="1">MSARMRIDVLTLFPEMFDGVFGTSILGKARDKGIVELSAVNFRQYSTSKHGQVDDTPYGGGGGMVLKPEPIFAAVEDLLRKREIEGGIVAAELPANESLSRPRIVLLCPQGETFTQKKAEEFAKEDHLIFICGHYEGYDERIRDGLVTDEISIGDYVLTGGELPAMVMIDSTVRLLPGVLGNENSAVTDSFSTGLLEYPHYTRPTEFRGMKVPDILLSGHHANIEAWRRRESLRRTLQRRPELLERITLTKQELKWLEELKREESALHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSL1</accession>
    <name>A0A010YSL1_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribonuclease 3</fullName>
            <ecNumber evidence="10">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Ribonuclease III</fullName>
            <shortName evidence="10">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rnc</name>
        <name evidence="14" type="ORF">SacsacDRAFT_0135</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="10"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282454.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.136"/>
    <dbReference type="HOGENOM" id="CLU_000907_1_3_9"/>
    <dbReference type="OrthoDB" id="1890943at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="10" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="13">
        <location>
            <begin position="5"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="12">
        <location>
            <begin position="160"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG83170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="229" mass="25809" checksum="93036B0600019CB5" modified="2014-06-11" version="1">MSGDLKQLQHKLGIQFADKPLLKQAFTHASYVNEHRFSQHHDNERLEFLGDAVLELTVSEFLYNRFPGRPEGELTKLRAAIVCEPSLVKFAEVLNFGAYVLLGKGEELTGGRSRPALLADVFESFVGALYLDQGLEAVRGFLDRYVFPQVAWDGKLQMSDFKTELQELTQHHNLGVLEYRIVEERGPAHEREFVSEVYMGERSLGRGTGRSKKEAEQQAAAAALETLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSL7</accession>
    <name>A0A010YSL7_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="9">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="9">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fabH</name>
        <name evidence="12" type="ORF">SacsacDRAFT_0140</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="9"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282465.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.141"/>
    <dbReference type="HOGENOM" id="CLU_039592_3_1_9"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="11">
        <location>
            <begin position="110"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="10">
        <location>
            <begin position="240"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="9">
        <location>
            <begin position="257"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG83175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="329" mass="35207" checksum="165E15A0179CDD7B" modified="2014-06-11" version="1">MKNLRPVGVIGAGKYVPERILDNAELEKMVETNDEWIVSRTGIRERHIAAPEQATSDLAYEASIKALASAGIKPEELDLIIVATITPDTSFPSTACILQDKLGAKKAAAFDLSAACSGFVYSLAAATGFIQNGMYNNALVIGADTLSRITDYTDRNTCVLFGDGAGAVVLGEVPQGRGFQSFDLGAEGAGGDQLKLPAGGSRLPASAETVDAKQHFIYMNGRDVFKFAVRVMGTATEEVLRKAEMTKDDIDLFIPHQANIRIIQSAMQRLNLSEDRVMINVDKYANTSAASIPLALVEAYEQGRIKEGDRVVMVGFGGGLTWGGAALIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSN6</accession>
    <name>A0A010YSN6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282490.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2384393_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="94" mass="10210" checksum="5BCA0B73350A409E" modified="2014-06-11" version="1">MEEKSAKPDYPNARDGRSPWLELWLHPRQVTRWFLNSDDPWKNALLLAVLSGALGGLSTASGDNWGDDLSMPGLIIRALVVGSIGGLLGYYLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSP3</accession>
    <name>A0A010YSP3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506756.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_161279_0_0_9"/>
    <dbReference type="OrthoDB" id="2069692at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="109" mass="12129" checksum="C49E6FF16BCB9100" modified="2014-06-11" version="1">MNELMMQMAVPMNLGGMIGLFGGLLLGMLGWGFGRYMQRKNRGLDERAETITARAKAFSWNLLIPAIMLSWVLVTLFEGIGLSFFVMMALFVISQIAYIAAAVYQNGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSQ7</accession>
    <name>A0A010YSQ7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Subtilisin-like serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">SacsacDRAFT_0170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506758.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_15_7_9"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07477">
        <property type="entry name" value="Peptidases_S8_Subtilisin_subset"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034202">
        <property type="entry name" value="Subtilisin_Carlsberg-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458146" evidence="5">
        <location>
            <begin position="26"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="155"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="413"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="458" mass="47867" checksum="D22CBB5906F2832B" modified="2014-06-11" version="1">MFRQIKGKKLIFSTISVICLLSAFAAFQLSNRIENVENVIAPKPVFDIFVKYSDQDGERLALNVTHDLKYHIYWNTNMMSLRTNEAGLAKLRASDSIQSIELSQNYKGIAQSLASLSDDAAPASSAASSASKIKQGAWGYDAIDASEAQTAGYTGKGVRIAILDTGISDKSGLQISGGTSTVEGVTSYNDDNGHGTVVAGIIGAKSKAYKGIAPDASLYAIKVMDKDGNGSTQSLAEGLDWAIRQHMDVINLSLSFPQQSNAVQELLKKAADQGITVIVAAGNAGTSDGTGDTLAFPAKSPETITVAAVDSGLKRADFSGTGSEVELSAPGVGIVSTSVSGKYKISDGTSMAAPFVSGMVAVMKQAYPNLSAEQLRAALQNSAVDLGASGRDNLYGYGMVSFDRLLGKNSVLADRPESSTPTVRDASTQTIAASDNSITPKSQTNTSNPPSAENGTFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSR9</accession>
    <name>A0A010YSR9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein-disulfide isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506760.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.182"/>
    <dbReference type="HOGENOM" id="CLU_000288_47_1_9"/>
    <dbReference type="OrthoDB" id="1678187at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="81"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="274" mass="29836" checksum="9B375BD421477FD2" modified="2014-06-11" version="1">MSKNKKPAPKNGKPQGAKKNTGGAARPQGTPRPQNQNTAASQWTSGSKRKKSNLGIIALGFVGLIVVLAVLIFVLTKVGENQTTSSAEPVILTSYDASNQPTLGNPDSNVQIVEFGDYKCPDCKIWTETVLPELQTKYLDTNEASFQFADYPFLADDSMLLALGAQALYEQNPEYFWAYNKAVYANQDTSKVRESWITEDYIVNLVKENVPDADIEKFTNDLKNKTYQAAVDADVKAGDDSKITGTPSIFVNGTKVENPTLENVEAAIEAAKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YST3</accession>
    <name>A0A010YST3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding domain-containing protein, AraC-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506762.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.195"/>
    <dbReference type="HOGENOM" id="CLU_000445_88_6_9"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="179"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="282" mass="32533" checksum="15B35AA96A0BC699" modified="2014-06-11" version="1">MKKADIRVVPTDGSYTHLPGVLVADHYRVSDDYVCYRPEGTKDWLIMYTLSGKGTVQTEEEGALHCSTGTVTLIPPGTLHYYFTNEGEVWEKIWAHYTPRPSWLDWLPSDSGNGAIDQVRIEDSRSREAVEKAFRRILAYRFDAAGDFREELMLNALEEIILLLAGLRAERRTLDPRIKIVLDLLAHEFSENFAIEDLARLVHLSPSRLSHLFKEQVGDSIIAILNGFRLKQAEKLLRYTPRPITEIAFSVGFNSPDYFTRQFVHYYGMSPLQYRKRHMSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSX2</accession>
    <name>A0A010YSX2_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, ribosomal protein N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282579.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_3_2_9"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="184" mass="21523" checksum="0BC8B8EA7DEA743E" modified="2014-06-11" version="1">MPRLIGERIMLREYRRDDLKSIRSWVNDPAVTDTLSDVFMYPHTEQSSETFLNKMLQGGDGLKSFVIAEKENEAYIGQIDLINIDWRSRCSSIAIVIGDSRQHGRGYGSEAIGLIQRFVFEELNLNRLQLQVYDYNLAGYHCYLKSGFKEEGRLRQRHFHKGHYRDIVEMGILKSEYEERSIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSY5</accession>
    <name>A0A010YSY5_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Arabinose efflux permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">SacsacDRAFT_0225</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.236"/>
    <dbReference type="HOGENOM" id="CLU_025894_0_1_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="9">
        <location>
            <begin position="17"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG83260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="432" mass="46990" checksum="0185942608EB69F6" modified="2014-06-11" version="1">MQSFRRMTAGIARWPRNVKLFFLANLLYQIGGGMFSVLYNLYIQGIGYNDAMNGRVVSIQSLATACIFIPIGLFGDRLSRKTLLVIGALFSGIVFALRAFAEAEPLLLVLAVCSGVFAAFFQVLAIPFLAESVKKSQRLALFSAYSSLMLAAQVLGSMGGGVLADTLQHSGIDHVLSLRFTLFVGGIATLAAFVPMLFIREQRTQPETAKISETQQSQPNAEQAKADTSGKKAPDGSSRIIFWFVLAQLPIGLGSGLVVPYLNLYFTNRFGVSISMMSLLISLGQIMTIVSMLIGPSLSKKVGPVRAVVIFQLLSLPFLLTTGFTNIALVASIAFLFRQALMNAANPIQSAVMVDRIPDNKRSIANSLTQTAFMLGWASMGPVQSFLVTTYGNYWGYAITFSITGALYVTASLLYYFKFRERPARRIGTAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSY9</accession>
    <name>A0A010YSY9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506770.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1795097_0_0_9"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="144" mass="16343" checksum="8F36983977425A15" modified="2014-06-11" version="1">MQIITCTEEHKDRLTEMWLISVHRTLYDLDPGDIEGYVHLFQENIVDKMELHGVRSRFGGELTGFIAMNGPKVELLVVHPHYQGQGISDLLLEHVAKRGELVVDVTEQAPDVYEYYQRLGFIEAGRSGTTLHLIRPSLIEQTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSZ3</accession>
    <name>A0A010YSZ3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe2+/Zn2+ uptake regulation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.252"/>
    <dbReference type="HOGENOM" id="CLU_096072_3_1_9"/>
    <dbReference type="OrthoDB" id="1630127at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="159" mass="18779" checksum="057591A7C0C7DD44" modified="2014-06-11" version="1">MISVEEQLKSMKQQMISKGYKSTIQREATMRVLLEHERDHMSAEDVYMRVKTRFPEIGLATVYRTLELLTELHLVEKMNFGDGVARFDLRSEDHEHMHHHMICSICGEVEEIQDDWLSELEQRVKREYGFNVSDHRLDFIGTFSSCKHGDCHRHRENAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YSZ5</accession>
    <name>A0A010YSZ5_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative HD superfamily hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.257"/>
    <dbReference type="HOGENOM" id="CLU_036524_2_2_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="35"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="226" mass="25352" checksum="2B5EC3DDFE85B083" modified="2014-06-11" version="1">MMHDDRSTQARQADILRAAAALAKSELEHEGSGHDWWHIHRVTELAKRIAAAEKADLFICELAALLHDLADEKLVDDPETGMKRTESWMLENGATAEEAAHVMEIISTLSFKGGAGKPMTTLEGKVVQDADRLDAIGAIGIARTFVYSGKKGRPMYDPNIPVRREMTPEEYRNGKDTAINHFHEKLLKLKDLLNTDSGLAIAEQRHAFMEEFLERFDREWNGTDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT11</accession>
    <name>A0A010YT11_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional antiterminator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282670.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.282"/>
    <dbReference type="HOGENOM" id="CLU_078802_0_0_9"/>
    <dbReference type="OrthoDB" id="1193348at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.24.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004341">
        <property type="entry name" value="CAT_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036650">
        <property type="entry name" value="CAT_RNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011608">
        <property type="entry name" value="PRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036634">
        <property type="entry name" value="PRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03123">
        <property type="entry name" value="CAT_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00874">
        <property type="entry name" value="PRD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01061">
        <property type="entry name" value="CAT_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50151">
        <property type="entry name" value="SSF50151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63520">
        <property type="entry name" value="SSF63520"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51372">
        <property type="entry name" value="PRD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRD" evidence="1">
        <location>
            <begin position="65"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="PRD" evidence="1">
        <location>
            <begin position="171"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="280" mass="32473" checksum="D75231CB63A59AAE" modified="2014-06-11" version="1">MIIEKVLNNNVLLTRNAKGKEVIVMGRGISFNKVIGDAVDEHKIDKIFMLNTNELTARLTELLNDIPVAHLETVKSIVEHAGRVLGEELNDNIYLSLTDHISYAIDRHSKGIDFKNAMLFEIKRFYKKEYAIGQDALKMIEEQLDVRLPEDEAGFIALHIVNARTDGAEMRLTMEMTEIVHHILNIVTYHYGIVLDESSLSYSRFLTHLQYFSMRLLRHEVQDSGEDFLYEQVRKSYVKAFECAKKIDDYLQSTYHQSLSKDEYVYLTIHIQRITTRGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT18</accession>
    <name>A0A010YT18_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0276</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282687.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.293"/>
    <dbReference type="HOGENOM" id="CLU_035117_0_5_9"/>
    <dbReference type="OrthoDB" id="1194694at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="NADP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="2">
        <location>
            <begin position="3"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_11" evidence="3">
        <location>
            <begin position="165"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="294" mass="30820" checksum="597DE3F77D3CB485" modified="2014-06-11" version="1">MTKLAWIGTGYMGLPMARNLLKAGHEVNVYNRTPAKAKPLADDGGKIVSSPKKAAEEAEAVFIMLTKGTAVEAVLEGEEGLLAGLEPNTVVVNMSTIAPGEAREFARRIQSAGGIYVDAPVSGSVAPAVNGQLVILAGGAEAAIEQCRPFFDALGKKTIVFGEVGAGSSAKLSINLLLGVMAQGISEALLAGEHAGLRREQLIEMIGESAVNTPMLAAKKDMWMNEEFPAAFMVSLLSKDLGLLTAEAKREGLDLPLAEAVDRTYADAVQSGKGELDMAAVWLELKERLPGSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT21</accession>
    <name>A0A010YT21_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282697.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1593364_0_0_9"/>
    <dbReference type="OrthoDB" id="1335440at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458888" evidence="1">
        <location>
            <begin position="24"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="167" mass="18839" checksum="879E748CFAC3EEE9" modified="2014-06-11" version="1">MRSLGVIAALAALTLSVSGPAVTELTAQFERNVNADMQTPTLRFEGTTLSHEQAERIAEDLKLRIMQQYSARYKLGEFEIEFTDEQPENGRIGIDVNVFFHMLPKGDLSRYPALRPETTSLYYIMIPESIDKQPGTSKTLRYELFDRADITLEETILTPLASVEIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT28</accession>
    <name>A0A010YT28_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcium-binding protein with excalibur domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0286</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282709.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.303"/>
    <dbReference type="HOGENOM" id="CLU_182235_1_1_9"/>
    <dbReference type="OrthoDB" id="2061710at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008613">
        <property type="entry name" value="Excalibur_Ca-bd_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05901">
        <property type="entry name" value="Excalibur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00894">
        <property type="entry name" value="Excalibur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458149" evidence="1">
        <location>
            <begin position="29"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Excalibur" evidence="2">
        <location>
            <begin position="32"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="88" mass="9545" checksum="9CAD93AF2AAE7E5E" modified="2014-06-11" version="1">MKKSLTYVLSFALLLAVAVPVSTQSASAAAKTYKNCTELNKDYKGGVAKSASVKNKGGKTKYKPFVSAELYEANKKSDRDKDFIACEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010YT42</accession>
    <name>A0A010YT42_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506784.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133817_2_1_9"/>
    <dbReference type="OrthoDB" id="1971664at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="170" mass="19063" checksum="D45D70BEE8F29175" modified="2014-06-11" version="1">MTAVQTTRDELSLIKSYLLLTHILKTFENDAKKLESDTPTQTSTLYTEMIRNASRCAAVLLSGIRREFKKRSIRMCEVQHSEKGVDADYLCRGLHGTMHIDHAPFHNEMELRMRAYLGISSTENRSAEPIVTDSGRQSAAPVRNYGHRTSKPGVSAKKKTSRPYSAGAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z6Y5</accession>
    <name>A0A010Z6Y5_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative Zn-dependent peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">SacsacDRAFT_0048</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282256.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="MEROPS" id="M16.A15"/>
    <dbReference type="PATRIC" id="fig|915437.3.peg.48"/>
    <dbReference type="HOGENOM" id="CLU_009902_3_3_9"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="3">
        <location>
            <begin position="11"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="4">
        <location>
            <begin position="166"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG83083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="421" mass="47162" checksum="C553DC23683A95BF" modified="2014-06-11" version="1">MEKYTLSNGLRVVAEHIPGSRSVSFGIWVKNGSRNETQADNGISHFIEHMLFKGTDRYNAREIAEQFDAIGGNVNAFTSKEYTSYYAKVLDEHLPIAMDTLADMFFNSKFDPEELAREKNVIFEEISMYLDDPDDLVHDLIVEAAYEGHPLAMPILGTQEHLEAMSSDDLMGFMNERYTINNTILAIAGNLGDDIRELLERHFGSFQRHGEEQSITVPSFDGGLVYRKKKTEQNHICLAFQGFGYDDPRQYAMALLNNSIGGGMSSKLFQEIREKRGLAYSVYSYHSAHIDSGYFTIYAGTAPKQTAEVLQLTREVLQDIQSNGLSESEIFKGKQQLKGSLIMGLEGSGSRMNRLGKNELMLGRHESIDETIAKVEAVTEKDVRLALDHLFAQPFAVAMVGNSDRAINALRRDELVPSSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z705</accession>
    <name>A0A010Z705_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Elongation factor Ts</fullName>
            <shortName evidence="6">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsf</name>
        <name evidence="8" type="ORF">SacsacDRAFT_0068</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282305.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.68"/>
    <dbReference type="HOGENOM" id="CLU_047155_1_1_9"/>
    <dbReference type="OrthoDB" id="1405357at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="7">
        <location>
            <begin position="27"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="6">
        <location>
            <begin position="81"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="215" mass="23833" checksum="1744B74A0F55D11B" modified="2014-06-11" version="1">MAVNASAVKELRERTGAGMLDCKKALEETNGDIDKAVDVLREKGLSAAANKAGRAATEGTVESYIHAGGRIGVLVEINCETDFVGKTDQFKNFARDIAMHIAAASPLYVRREEVPAEVVEKEKEILKAQALNEGKPEKIVEKMVEGRVNKYYEENCLLEQSFVKDPDKTISQLLNEKISTIGENISIRRFARFELGEGLEKKVDNFVEEVMAQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z721</accession>
    <name>A0A010Z721_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flagellar biosynthesis protein FlhA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">flhA</name>
        <name evidence="8" type="ORF">SacsacDRAFT_0083</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.84"/>
    <dbReference type="HOGENOM" id="CLU_015346_3_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042194">
        <property type="entry name" value="FHIPEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042193">
        <property type="entry name" value="FHIPEP_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042196">
        <property type="entry name" value="FHIPEP_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025505">
        <property type="entry name" value="FHIPEP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006301">
        <property type="entry name" value="FlhA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001712">
        <property type="entry name" value="T3SS_FHIPEP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30161">
        <property type="entry name" value="PTHR30161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00771">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005419">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00949">
        <property type="entry name" value="TYPE3IMAPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01398">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00994">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="678" mass="74517" checksum="EEAA446BF6AC6194" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z726</accession>
    <name>A0A010Z726_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flagellar biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">SacsacDRAFT_0088</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282353.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105734_1_0_9"/>
    <dbReference type="OrthoDB" id="1876061at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022781">
        <property type="entry name" value="Flagellar_biosynth_FliO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04347">
        <property type="entry name" value="FliO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="180" mass="19921" checksum="5F2560BD9F31F15E" modified="2014-06-11" version="1">MLLLSEGQPNFSADTGVYSYLVWVIFVLIAIVALIVFLIRYLGKKNRGWFGGRSVRTLGGVGLGQNKSLQIVEIGGSIYLIGVGENISLIDKISDAEEVEMLIGALVQDSAGPNIALPAWAEKLTSRFRNGSNTPSETEELDSSSFQQLFETRLREASDRRRKVDDLLEKEESVDRSREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z735</accession>
    <name>A0A010Z735_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein, possibly involved in motility</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282365.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_173020_2_1_9"/>
    <dbReference type="OrthoDB" id="2007051at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009384">
        <property type="entry name" value="SwrD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39185">
        <property type="entry name" value="PTHR39185"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06289">
        <property type="entry name" value="FlbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="74" mass="8247" checksum="9EC18C6ECE6C3CD0" modified="2014-06-11" version="1">MIPVTRLNGSPLWLNALQIELVEETPDTYVTLVNGKRMIVLEKAADVVKLMTEYYATIGLHSASIKVQNTGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z740</accession>
    <name>A0A010Z740_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282375.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072019_0_0_9"/>
    <dbReference type="OrthoDB" id="1773408at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="318" mass="33352" checksum="77CE530EA2A53D13" modified="2014-06-11" version="1">MAKTGAEAEANLEEEPSGSKAGRILLFAAPVLFAIVLVGVLLTLLNPTARNSVLETANKIPVVGSMLPKPTYTPEQQAQRQEEKQAASAEATINQLKTQLEQKNTELKTAQKAQADTQTQVDALQKQVDDAKAQQEQTAAAAEPEKDPGPSQQVKQLAQTYGSMSASKAAPILETLTDEEIAMILGAMSTEQRSGIMQKMTADKAAKVSIMLKSAASSEALETAANKARAAANNSEQPAQAATSTTGSLNQDQLSQTFSSMDASSAATLLIQMAKTNQAKVLTILKSVDDSTRSSILSQMASTDSETAASLANKLIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z746</accession>
    <name>A0A010Z746_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Flagellar M-ring protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">SacsacDRAFT_0103</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The M ring may be actively involved in energy transduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the FliF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282382.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.104"/>
    <dbReference type="HOGENOM" id="CLU_028108_2_1_9"/>
    <dbReference type="OrthoDB" id="167675at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009431">
        <property type="term" value="C:bacterial-type flagellum basal body, MS ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013556">
        <property type="entry name" value="Flag_M-ring_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000067">
        <property type="entry name" value="FlgMring_FliF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006182">
        <property type="entry name" value="FliF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043427">
        <property type="entry name" value="YscJ/FliF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046">
        <property type="entry name" value="PTHR30046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046:SF0">
        <property type="entry name" value="PTHR30046:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01514">
        <property type="entry name" value="YscJ_FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08345">
        <property type="entry name" value="YscJ_FliF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004862">
        <property type="entry name" value="FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01009">
        <property type="entry name" value="FLGMRINGFLIF"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00206">
        <property type="entry name" value="fliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF" evidence="11">
        <location>
            <begin position="46"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF_C" evidence="12">
        <location>
            <begin position="262"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR004862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG83138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="528" mass="56984" checksum="5D8A6BB0C0E2E454" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z784</accession>
    <name>A0A010Z784_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsP</name>
        <name evidence="4" type="ORF">SacsacDRAFT_0128</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282436.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.128"/>
    <dbReference type="HOGENOM" id="CLU_100590_5_0_9"/>
    <dbReference type="OrthoDB" id="1937072at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_S16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="90" mass="10232" checksum="8528130606636D8E" modified="2014-06-11" version="1">MATRIRLKRMGAHKAPFYRIVVSDSRSPRDGRFIEEIGYYNPVAEPQVVSINEEKALAWLQTGAQASDTVRNLLSKAGIMKKFHESKLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7C8</accession>
    <name>A0A010Z7C8_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.158"/>
    <dbReference type="HOGENOM" id="CLU_006462_1_1_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032091">
        <property type="entry name" value="Malt_amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16657">
        <property type="entry name" value="Malt_amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="21"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="563" mass="64794" checksum="1E8D9A8C00EA8FB8" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7I6</accession>
    <name>A0A010Z7I6_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NAD(P)H-nitrite reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">SacsacDRAFT_0198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282559.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.205"/>
    <dbReference type="HOGENOM" id="CLU_003291_0_0_9"/>
    <dbReference type="OrthoDB" id="1128731at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041575">
        <property type="entry name" value="Rubredoxin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18267">
        <property type="entry name" value="Rubredoxin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="7"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_C" evidence="6">
        <location>
            <begin position="321"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Fer2_BFD" evidence="4">
        <location>
            <begin position="418"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="722" mass="77065" checksum="FBC104F389A80322" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7M3</accession>
    <name>A0A010Z7M3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282585.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2919999_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="61" mass="6785" checksum="DA59AA61C10380B5" modified="2014-06-11" version="1">MWNFILGVAAITMGLRFLYGTISRGRSIVTVKILGMQVPIRVIQVAMSLFVIGLGVYMLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7S8</accession>
    <name>A0A010Z7S8_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282703.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091006_0_0_9"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="202" mass="21626" checksum="9410500DCD42AEC5" modified="2014-06-11" version="1">MAKALVIGGEGTLGSAIVAKLKEHNIETFTAGRSTGDYKVDMTDTSSISALFDEVGELDHVIIAAGSTHYDAVPDLTPENNLKSINNKLLGQVNTVLLGQHKLKDNGSFTLVSGILKDYPIPRGASSSMVNGAIDAFVQAAALELPRGIRLNSVSPGLLTESAEKYADFFKGFNPVPAERVANYFVRSVLGIESGRTYYIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010Z7T3</accession>
    <name>A0A010Z7T3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenazine biosynthesis protein PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282717.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.306"/>
    <dbReference type="HOGENOM" id="CLU_048756_0_2_9"/>
    <dbReference type="OrthoDB" id="1468060at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="303" mass="33256" checksum="BA96A0C6959C7A32" modified="2014-06-11" version="1">MTAVTVFHYEAFSAIPGKGNPAGIMLDADHLTDAQMQEIATKVGFNETTFVCRSHAADVRLRYFTPGYEMDLCGHATMASLYALRTRGLLHQDAATIETRIGVLPVELTYGENGDEKSLSMRMRQGNPAFIPFEGDEYALLASIGLSMSDLDERYPIVYGSTGSWTVLIPIRSLEAFSRMVPDNASFPGMLTQNPQASLHPFCLETFDPQARMHARHFCPPHSGMIEDPVTGTATGVMGAYALTYMEAHLPRTDFIVEQGLEMGRDGRVKVEAERLSDGGIDIRVSGGATFVTDMQIMLNESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWJ5</accession>
    <name>A0A010ZWJ5_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2-oxoglutarate dehydrogenase E1 component</fullName>
            <ecNumber evidence="5">1.2.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Alpha-ketoglutarate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">odhA</name>
        <name evidence="7" type="ORF">SacsacDRAFT_0004</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + 2-oxoglutarate + H(+) = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:12188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10483"/>
            <dbReference type="Rhea" id="RHEA-COMP:10484"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="1.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="5"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282152.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.4"/>
    <dbReference type="HOGENOM" id="CLU_004709_1_0_9"/>
    <dbReference type="OrthoDB" id="29166at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01169">
        <property type="entry name" value="SucA_OdhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023784">
        <property type="entry name" value="2oxoglutarate_DH_E1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="PTHR23152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="6">
        <location>
            <begin position="598"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="960" mass="107664" checksum="DD959634F9B9AB36" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWK0</accession>
    <name>A0A010ZWK0_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative bacillithiol system oxidoreductase, YpdA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282162.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.9"/>
    <dbReference type="HOGENOM" id="CLU_067342_0_0_9"/>
    <dbReference type="OrthoDB" id="324612at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023856">
        <property type="entry name" value="Bacillithiol_biosynth_YpdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04018">
        <property type="entry name" value="Bthiol_YpdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="335" mass="36970" checksum="E6D57842B3C06EE8" modified="2014-06-11" version="1">MEKEDVLIIGAGPCGLSAAIECGRRGLSVRIIEKHNVVHSIYLYPTNMQFFSTAELLEIGDVPFTSPNEKPFRHEALAYYRKVADRYNLRISSYEEALAIKPQEDGTFKVETRDRAGNEREYAAGSVVVSTGYFDHPNELGIPGEEKDKVTHYFREAHPYAGMNVAIVGGSNSAVDAALELIRVGAKIDMIYRRTEISQHIKPWVRPLFEGMIAKGKITLHLGSKLTEIGEDYVVVQGPETESRIHNDFVLAMTGFRPDRKLLTEAGAQMSDDLDKPVFDAETMETGVPGLYVAGVIASGRNANEVFIESGRLHGGFIADHIAKRANAEENSVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWK9</accession>
    <name>A0A010ZWK9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative quinone oxidoreductase, YhdH/YhfP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.19"/>
    <dbReference type="HOGENOM" id="CLU_026673_26_3_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014188">
        <property type="entry name" value="Acrylyl-CoA_reductase_AcuI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF1">
        <property type="entry name" value="PTHR43677:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02823">
        <property type="entry name" value="oxido_YhdH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="17"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="334" mass="35509" checksum="F7D26DECF2C4776F" modified="2014-06-11" version="1">MMTEKFRAFWLEETETGVTGAVKKIETDDLPQGEVLVRVRYSDVNYKDGLASIKEGRIVREYPFIPGIDLAGEVVASEDSRFAIGDQVLCTGYGLGVSHFGGYSEQARVPADWLVKLPEGLTLREAMILGTAGFTAGMSVEAILSAGITPESGPILVTGASGGVGSVAVSILAKLGFEVTASSGKEQEWELLKRLGASHTISREEAQTPSKGPLGKGLWSAIVDPVGGAGTGERLKAIRYRGVLALSGLTGGGDFGTSVHPFILRGVTLAGIDSVQCPLPLRLDVWDKLATDWKPESLFEQAVHEVSLEQLPEAFDRILKGQAVGRQLVKVSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWL7</accession>
    <name>A0A010ZWL7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_018974962.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.29"/>
    <dbReference type="HOGENOM" id="CLU_168904_1_0_9"/>
    <dbReference type="OrthoDB" id="1985350at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007347">
        <property type="entry name" value="SpoVS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35331">
        <property type="entry name" value="PTHR35331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04232">
        <property type="entry name" value="SpoVS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="86" mass="8694" checksum="B9CD8E029F022A57" modified="2014-06-11" version="1">MDVLKVSAKSNPNSVAGALAGVLREQGAAELQAIGAGALNQAVKAVAIARGFVAPGGVDLICIPAFTDVVIDGEERTAIKLIVEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWM1</accession>
    <name>A0A010ZWM1_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative competence-damage inducible protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cinA</name>
        <name evidence="3" type="ORF">SacsacDRAFT_0034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CinA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282213.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.34"/>
    <dbReference type="HOGENOM" id="CLU_030805_9_3_9"/>
    <dbReference type="OrthoDB" id="1834406at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00226_B">
        <property type="entry name" value="CinA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041424">
        <property type="entry name" value="CinA_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008135">
        <property type="entry name" value="Competence-induced_CinA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18146">
        <property type="entry name" value="CinA_KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006728">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00200">
        <property type="entry name" value="cinA_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="2">
        <location>
            <begin position="4"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="421" mass="45686" checksum="D924F4FD04D4B77D" modified="2014-06-11" version="1">MKAEIIAVGTELLLGQIVNTNAQYLSQELAAIGIDVYFQTVVGDNKERLKEAIRQAQGRADVLVFSGGIGPTQDDLTKDAIAEVLGRELRTDRPAMDKLTEFFADRGVPMTENNKRQALVIDGCTPLPNATGLAVGVAISSDSHHYIVLPGPPSELKPMFADQAKSWLLHQVLTGEMPIYSRILKFAGIGESALEDKLLDLIDAQTDPTIAPYAKEGEVAIRLSTKAENIQEANVRLTALEVQIQSRLSEHMYASEDVPIEETIVKMMADMGLTVSAAESCTGGMVMQSLTTIPGSAAMLRGGIVCYSNEMKEKLLNVPHDYLEGTDAPGAVSEEVAVVLAEQVRMIADADFGLSVTGVAGPGYSERKPVGLVYIGIAEKGGKTEVFELRIKGNRETIRKRSTKTLLYRLWRRLVQAEKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWP9</accession>
    <name>A0A010ZWP9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CDP-diglyceride synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282294.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.64"/>
    <dbReference type="HOGENOM" id="CLU_037294_2_2_9"/>
    <dbReference type="OrthoDB" id="1533756at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="266" mass="28834" checksum="0B6531BB8BC32C8B" modified="2014-06-11" version="1">MKQRIITGVVAGVLFLGLCVLGGFGYPALIMLMALVGFYEFAKMSTGAPFRAEAWIGYLAVAYLTFPWQVWDLDFPIPPQHAIWLSLLLLLCATVLTKNEINIKQASLLFLGAVYVGLGFYYIAISRETPDGHGLFWTFLLLLSIWGSDAGAYFTGKAFGKNKLWPAISPNKTIEGAVGGILIAVVIALGFSLAAPELLDPLRAMLIGLAASVVGQMGDLIQSAYKRVYGIKDSGSILPGHGGILDRCDSWLAVFPFVHILFLLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWQ6</accession>
    <name>A0A010ZWQ6_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsB</name>
        <name evidence="7" type="ORF">SacsacDRAFT_0069</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282308.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.69"/>
    <dbReference type="HOGENOM" id="CLU_040318_1_2_9"/>
    <dbReference type="OrthoDB" id="1623045at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="232" mass="26407" checksum="2A54CEC6040B437F" modified="2014-06-11" version="1">MAVISMKQLLEAGVHFGHQTRRWNPKMDRYIFTERNGIYIIDLQKTVKKVDEAYNFVKNLAGEGGTILFVGTKKQAQDSVKEEAERCGMYFINQRWLGGTLTNFQTIQKRIDRLKKLEAWEEDGTFEVLPKKEVILLRKEKDRLEKFLGGIKNMKKLPSALFIIDPRKERIAVAEARKLNIPIVGIVDTNCDPDEIDYVIPGNDDAIRAVKLLTGKIAEAVIEANQGEQTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWR0</accession>
    <name>A0A010ZWR0_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase sigma factor, FliA/WhiG family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">SacsacDRAFT_0074</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282322.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.75"/>
    <dbReference type="HOGENOM" id="CLU_014793_8_1_9"/>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012845">
        <property type="entry name" value="RNA_pol_sigma_FliA_WhiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02479">
        <property type="entry name" value="FliA_WhiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="5">
        <location>
            <begin position="221"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG83109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="262" mass="30265" checksum="81E2005612B1E5B2" modified="2014-06-11" version="1">MDERKSGQLNHLDLWIRWKEHNDVEAKKKLIENHLSIVDYVSSRLAVGLPKNVSKDDLASNGVMGLIDAIEKFDYKRGLQFETYASWRVRGAILDGLRQGDWVPRSVREKAKKIEEAYQKLEQEHMRGASDQEMSEFLGISEKEFQQMLQDVSVMSLVSLEDPIREEESETRLSVMVDEKAKNPDHKVNEFYLKEALGKGIEKLTEKERIVISLLYYEDLSLSEIAEVMSLSPSRISQLHSKAILRLRGTLDKQKSLLMQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWU0</accession>
    <name>A0A010ZWU0_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar FliJ protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">SacsacDRAFT_0099</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.100"/>
    <dbReference type="HOGENOM" id="CLU_139638_1_1_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012823">
        <property type="entry name" value="Flagell_FliJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02050">
        <property type="entry name" value="FliJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02473">
        <property type="entry name" value="flagell_FliJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG83134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="148" mass="17132" checksum="9097FF1878D2199F" modified="2014-06-11" version="1">MLKFNYSFQKVVDLKTSEKNHAEMHLSSAIGQLNAEEQTLGRLFSDKSSLVDSIQEQTVGAVSALQLQQMQDYVNYIDQCILQKRQDIQTAQVKVEEKKEKLTTKMLDEKVWLQARGKALESFEKEEMLREQNELDEMATVRFASRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWU7</accession>
    <name>A0A010ZWU7_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellar hook-basal body complex protein FliE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fliE</name>
        <name evidence="4" type="ORF">SacsacDRAFT_0104</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the FliE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282384.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.105"/>
    <dbReference type="HOGENOM" id="CLU_147249_3_0_9"/>
    <dbReference type="OrthoDB" id="1581972at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00724">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001624">
        <property type="entry name" value="FliE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34653">
        <property type="entry name" value="PTHR34653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02049">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01006">
        <property type="entry name" value="FLGHOOKFLIE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00205">
        <property type="entry name" value="fliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="103" mass="11434" checksum="87244D25A14B79CC" modified="2014-06-11" version="1">MIQNHMFNPVQLANRAVSSTQETASTTPHEAMQGFGQYLQDALQGVSDMEKTADQTGKQFMLGQASVDQVMITSEQALLGLQLTSQVRNKVIEAYQEIMRTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWW9</accession>
    <name>A0A010ZWW9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Septation ring formation regulator, EzrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">SacsacDRAFT_0124</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282430.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.124"/>
    <dbReference type="HOGENOM" id="CLU_352618_0_0_9"/>
    <dbReference type="OrthoDB" id="1242978at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005940">
        <property type="term" value="C:septin ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000921">
        <property type="term" value="P:septin ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010379">
        <property type="entry name" value="EzrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06160">
        <property type="entry name" value="EzrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0717">Septation</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001459253" evidence="13">
        <location>
            <begin position="29"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="TPM_phosphatase" evidence="14">
        <location>
            <begin position="37"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="744"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="645"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EXG83159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="805" mass="87843" checksum="FAEF463039FBBAAA" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWY1</accession>
    <name>A0A010ZWY1_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromosome partition protein Smc</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smc</name>
        <name evidence="6" type="ORF">SacsacDRAFT_0134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for chromosome condensation and partitioning.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282452.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.135"/>
    <dbReference type="HOGENOM" id="CLU_001042_2_2_9"/>
    <dbReference type="OrthoDB" id="1149850at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01894">
        <property type="entry name" value="Smc_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02168">
        <property type="entry name" value="SMC_prok_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="5">
        <location>
            <begin position="521"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="416"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="886"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="675"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="766"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="416"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EXG83169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="1189" mass="134957" checksum="5EDBC50B6D532492" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZWZ3</accession>
    <name>A0A010ZWZ3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative metal-binding protein, possibly nucleic-acid binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282473.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.145"/>
    <dbReference type="HOGENOM" id="CLU_100236_1_1_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003772">
        <property type="entry name" value="YceD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02620">
        <property type="entry name" value="YceD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="169" mass="18606" checksum="3B94D67E12DE82DC" modified="2014-06-11" version="1">MRLHLRRTIQNGEPVQLSGNVPIERTIEGRTDVISASPVLVELTASPSLDGTVGVSGTLTGHLDMVCSRCLETARIELDIPFEERFKQREEDEADLEDDEDMILADDDVIELSPYLEEYLTLGMPSAPLCKEDCKGLCQTCGSNLNETACGCDNTVIDPRLAGLKDFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX04</accession>
    <name>A0A010ZX04_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282488.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2059737_0_0_9"/>
    <dbReference type="OrthoDB" id="1925511at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="119" mass="13071" checksum="F1E13050B8A3D788" modified="2014-06-11" version="1">MRVVIGQISGRANLMIGALLIPKLLIACSELFASDTPNLDANSLFSFVFSAITVIEFALGMWLFIVSLHAIGEAHGFSAWKSFAVEFILGLILFVVLIIVIAIVFSVSGPPLWWLYENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX19</accession>
    <name>A0A010ZX19_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribose-5-phosphate isomerase A</fullName>
            <ecNumber evidence="2">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Phosphoriboisomerase A</fullName>
            <shortName evidence="2">PRI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpiA</name>
        <name evidence="3" type="ORF">SacsacDRAFT_0169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282509.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.171"/>
    <dbReference type="HOGENOM" id="CLU_056590_1_0_9"/>
    <dbReference type="OrthoDB" id="1681738at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="25"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="80"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="93"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="222" mass="23639" checksum="A820CA96E4779AD6" modified="2014-06-11" version="1">MNTKKLAAERAVESIEEGMTVGLGTGSTAYFAIEKLGQRVREGLTIRAVATSKRSEEQALGLGIPIVPFAEVGRIDITIDGADEVDGNLQLIKGGGGALLREKIVAARSDKMFVIVGEDKLVETLGAFPLPVEIVPFAHEWTLDNLKALHLNPELRLDNGDLYVTDNGNYIADCHGVSITDPAALHASLNAIPGVVENGLFVDMAHTVIVGRENGSIDTITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX25</accession>
    <name>A0A010ZX25_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD hydrolase, subfamily IA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0174</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282516.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.176"/>
    <dbReference type="HOGENOM" id="CLU_045011_8_1_9"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011951">
        <property type="entry name" value="HAD-SF_hydro_IA_YjjG/PynA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02254">
        <property type="entry name" value="YjjG/YfnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="238" mass="26459" checksum="FF7B93E1115118AA" modified="2014-06-11" version="1">MKNYQYILFDADDTLLDFQRCEREAFTASLTESGFGLDFDLCFNSYTTINRALWLDYEQNKVTQTQLRSERFRRLFTQLAIESDPEAFGATYLRHFAAGSFLTPDALAVCDALKSKLHLSIITNGIGDVQFSRIAGSELKDRFEHIIVSDDVGSAKPAPEIFDYAMRKIGCEDKSQVLIVGDSLSSDIRGGHDYGIDTCWYNPGGLENTSGIVPTYEIAKLTDLLALAGSETETASKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX56</accession>
    <name>A0A010ZX56_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051507438.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.201"/>
    <dbReference type="HOGENOM" id="CLU_061355_0_0_9"/>
    <dbReference type="OrthoDB" id="1974930at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010343">
        <property type="entry name" value="ArAE_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06081">
        <property type="entry name" value="ArAE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="359" mass="40966" checksum="139B20A4155FE213" modified="2014-06-11" version="1">MNFGARMLKTGIAVTLALYLTTLLSLTPPVIAAIAAIFAMQPTIYKSWTYFLDQLLTNTLGAVIAVTAGRLLSSEPIAVGLTCIVVIMICLKMKRADTIGLTLVTVISVMEASGDLGFALNRFLISVIGIFSAFFINVVVLPPKPREQFIGQIQSTFSQLSLLMRTAVSDEIKENVFRDEQKALEGSIQSLTEKYNLLEEDQHKRRRPSYTESRHLVVYKQMLHTLRKGTEVVEAVEEHYFPTARTLLLDKLFDDQLEYMIKYHEHVLLKFEGKLKPDDLPWQNLEEENERFSQAMKEYMQQQEGSTMRLSIVAAEIQAYGYQLERLNRLVEHYGDSKRNAPKPWTHWLNPKNWSKGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX74</accession>
    <name>A0A010ZX74_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282575.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.212"/>
    <dbReference type="HOGENOM" id="CLU_023194_19_0_9"/>
    <dbReference type="OrthoDB" id="1840839at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="133"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="339" mass="39130" checksum="7D4336B19459EFFC" modified="2014-06-11" version="1">MLTIGYVGNGKSTNRYHLPFSFNRDTINVKTIYARNLNKSEWDAVPGVQYTDDLAQLLNDAEIDLIVVCTHLDSHYEFAKAALDHGKHVLVEKPFMKTVAEAKAIFDYAKERGLIAQCYQNRRYDSDFLTTQKVIESGKLGELIEVEAHYDYYRPEIPLAARQFSKYNSYLYGHAIHTLDQILSQFGKPERVHYDVRQLLGSGRMNDYFDLDLYYGALKVSVKSSFFRLKERPSFVVYGQKGVFVKQTKDRQEEHLKLFYLPQGNADFGLDTPEHYGTLTYIDEEGMYREEKIISEKGDYARIYDDLYAAIKQGADKRIKDEETLAAMEMLETGIAQCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZX94</accession>
    <name>A0A010ZX94_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative aminoglycoside phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282578.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078715_0_0_9"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="48"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="325" mass="35860" checksum="A0EAA94D6AA6238A" modified="2014-06-11" version="1">MNDLNKANEINSSQDGVSGHVPELLGRNIAPLGEIIEAYPIRAGVSADRKYKVHFYGYDGAYLLRLFDETALAFKRSEFEALHRMQAMTVHCSRPIAMGRWETEGTYFLLVSYIDGADAQRTLPTSPKPQQLRVGMQAGEELSRISCYPAPEGMESWSNRYIRRTQQELDVLKSKGITSCGVEAATAKIRSSANLTATRPSVFLHGSFQPANLIVHGGRLAGVVGFGGFDWGDPLYEFARLGLYSRGVSTLFCTGQILGYHGGQEPDSEFWELYALYAASGAVSLLAQTSENENSELTTAIEWVDRLAKDHEGFSNVRPSWFAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXB3</accession>
    <name>A0A010ZXB3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulator of stationary/sporulation gene expression</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_018975153.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.246"/>
    <dbReference type="HOGENOM" id="CLU_158484_0_1_9"/>
    <dbReference type="OrthoDB" id="1942483at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="5"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="87" mass="9848" checksum="F30E92F97F641A71" modified="2014-06-11" version="1">MKATGIVRRVDELGRVVIPIELRRTMGIDIKDGLEIFVDGERIILRKYAPTCIFTGEAEDLVYFKGKMVSKAAIEELIELYQSSEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXB7</accession>
    <name>A0A010ZXB7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.251"/>
    <dbReference type="HOGENOM" id="CLU_1748335_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="149" mass="16637" checksum="B066FDAB018C54C4" modified="2014-06-11" version="1">MDEDKERGPGRKAKSDGRAEGAQTFRRGRALHFLERLELKRETLAAQLEENGFESIRPVIAGELKAVDGIIREFIQVFELHEKPEGCERGQGERRGRRGHGRGSRHGEQRESEQEGVHDSRQEAESGEMTKDESGLGQSKASDRGEAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXD0</accession>
    <name>A0A010ZXD0_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282646.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.268"/>
    <dbReference type="HOGENOM" id="CLU_331460_0_0_9"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="75"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="144"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="447"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="864" mass="91706" checksum="D26D5AD4605DCC6F" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXD9</accession>
    <name>A0A010ZXD9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="16">PTS system protein beta-glucoside-specific component, Glc family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">SacsacDRAFT_0264</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282667.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.281"/>
    <dbReference type="HOGENOM" id="CLU_012312_2_1_9"/>
    <dbReference type="OrthoDB" id="328780at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00212">
        <property type="entry name" value="PTS_IIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036878">
        <property type="entry name" value="Glu_permease_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018113">
        <property type="entry name" value="PTrfase_EIIB_Cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001127">
        <property type="entry name" value="PTS_EIIA_1_perm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013013">
        <property type="entry name" value="PTS_EIIC_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011297">
        <property type="entry name" value="PTS_IIABC_b_glu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001996">
        <property type="entry name" value="PTS_IIB_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00358">
        <property type="entry name" value="PTS_EIIA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00367">
        <property type="entry name" value="PTS_EIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55604">
        <property type="entry name" value="SSF55604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00830">
        <property type="entry name" value="PTBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01995">
        <property type="entry name" value="PTS-II-ABC-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51093">
        <property type="entry name" value="PTS_EIIA_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00371">
        <property type="entry name" value="PTS_EIIA_TYPE_1_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51098">
        <property type="entry name" value="PTS_EIIB_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01035">
        <property type="entry name" value="PTS_EIIB_TYPE_1_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51103">
        <property type="entry name" value="PTS_EIIC_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="418"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="14">
        <location>
            <begin position="6"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-1" evidence="15">
        <location>
            <begin position="108"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIA type-1" evidence="13">
        <location>
            <begin position="505"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate; for EIIB activity" evidence="11">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EXG83299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="635" mass="66063" checksum="016E999CEC12A705" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXE9</accession>
    <name>A0A010ZXE9_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycopeptide antibiotics resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506778.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077618_5_3_9"/>
    <dbReference type="OrthoDB" id="1262421at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ" evidence="3">
        <location>
            <begin position="19"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="172" mass="19022" checksum="34B7A969B0771D66" modified="2014-06-11" version="1">MKAKVIVVKVLAGLVLLGYGGLLLYWMFWGFGRSAHISGDFRYNIVPFETIQLFARSASWDNLRAPLINLAGNVAVFVPFGVLFPILFGKCRNYFGFLTRFLLFIVILELAQGVLGAGVADVDDVILNSIGASLGYIGYRLIAGPEQKRNGRAHARTRSANARSRSGQERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A010ZXF2</accession>
    <name>A0A010ZXF2_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0280</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282695.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_3_9"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008358">
        <property type="entry name" value="Sig_transdc_His_kin/Pase_MprB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01780">
        <property type="entry name" value="LANTIREGPROT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="88"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="301" mass="34586" checksum="73DC92B5B09696CC" modified="2014-06-11" version="1">MNILLTVLAVLLVAQTIYLLHYKAQIRDIGNQLHFIMQNGSFKQVNTQLRSREMMTLIRGCNQLLDQQKKADRQYARKNEEINATIVSLSHDIRTPLTALDGYLQLARQAEEFSDKDRYMEQAKSRIGQLSKLIDELFLYTKLQNPEYLIQQEPLDILASLQHNLFAFFDDFSRQGTEPELRLPASSVRVNGNVHALDRVFANILSNYFAHGTGTLSVVCEEEAERVRICFANRLRKGERVDTERVFNRFYKEDASRGVRSSGLGLSIVKSLMENMHGHAEADSEQGMFVIRLIFVKARKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0L9</accession>
    <name>A0A011A0L9_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="2">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">carA</name>
        <name evidence="4" type="ORF">SacsacDRAFT_0007</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282156.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.7"/>
    <dbReference type="HOGENOM" id="CLU_035901_2_1_9"/>
    <dbReference type="OrthoDB" id="662268at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="3">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="408" mass="44335" checksum="6A55BA1A6A1E785D" modified="2014-06-11" version="1">MKARLLLEDGTLFTGISFGSDKQMTGEVVFNTGITGYQEVLSDPSYCGQIVTMTQPLIGNYGINREDFEAIRPWIHGFVVRRHETAPSNWRSEYDLGTLLKEYDIPGIADIDTRMLTRRLRNQGTLRGLITTGSASTEELLEQLNAASALRDQVNQVSTPRAYRVPGTKQRVVVIDYGSKAGIVRELGDRGCDVIVVPHTSSAAEINRYNPDGVLLSNGPGDPKDVPQAINTVRELIGQLPLFGICLGHQLFALASGADTTKLKFGHRGSNHPVKEVASGRCLITSQNHSYSVLETTLDNTDLEITHVNNNDGSVEGLKHKSAPAFSVQFHPEAAPGPMDSNRLFDEFLQMIDEFKASRAPFVSSTTKSRTAAAVAGASTVASHQQIKTKEADVATPPMEKVLAPSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0N7</accession>
    <name>A0A011A0N7_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglutaminase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506751.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052009_1_0_9"/>
    <dbReference type="OrthoDB" id="1574236at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458469" evidence="1">
        <location>
            <begin position="31"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="162"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="356" mass="39283" checksum="9B78B9E94A82020B" modified="2014-06-11" version="1">MKKKRIALYLAATLVGASAVMPVAPRAAIAASSDTSIVSSITGAFEQKKTTLTVNMTSSQLSRIHSLLDSASAQSDPYARYTLDRVDTEYSVRGSKATVRFTISYLENKQQADYVTAQAKATLKTIVKAGMSEEEKVKVIHDYIVKKFAYDESMTRYSAYEGLTKGTTVCQGYALLAYRMFSLAGIENHIVEGVAGGQAHVWNKVKVDGKWYNIDMTWDDPTPDRKNEVSYSYYLVTDKLLARDHAWTKNNLPAATSDYRTLLAQKAKNSAKHRNLLAAIGGEITASTAALKQKVLSSIANGKAELTVQHDFNSNSPKSVLDQIMKACRETDVKNVRYGYQIADNGMAILKFAFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0P3</accession>
    <name>A0A011A0P3_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Regulatory protein RecX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">recX</name>
        <name evidence="7" type="ORF">SacsacDRAFT_0032</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Modulates RecA activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the RecX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282210.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066607_4_1_9"/>
    <dbReference type="OrthoDB" id="2025178at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01114">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003783">
        <property type="entry name" value="Regulatory_RecX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33602">
        <property type="entry name" value="PTHR33602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02631">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EXG83067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="263" mass="30455" checksum="25BE17E02DD3A072" modified="2014-06-11" version="1">MAFGKRSYGNRRNYKQSESTEEEENKKARREERLNHFGDFPEDESQEVTLVELLRRPVNSYRIYFGPHYVTVHESTMIRYGMTKGSFFDKDAVQEIVQDNEQQVAYSQALNYLSFKPRTSGEIEQKLLEKELDPEAVAATVKRLVDEKLIDDAFYAQEWTRQRINGKKKGKVVVKQELRRKGIDPELIDDALEAMGDDAELRSAEELAAKKWRTTKGELWDRKRKTAAFIMRRGFSSDIARKALDHVLSSEGEDSEGLGTEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0P8</accession>
    <name>A0A011A0P8_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0037</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282222.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.37"/>
    <dbReference type="HOGENOM" id="CLU_047530_0_1_9"/>
    <dbReference type="OrthoDB" id="2071222at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="360" mass="37619" checksum="67F1D584F1CC8E62" modified="2014-06-11" version="1">MSDLGQQLKDARMQKGLSLEDVQEMTKIRKRYLEAIEQGDFKVLPGSFYVRAFIKTYAEAVDLDPELLLQNHPKDVPAAEPENVMEPVLTKRSARTSAGGGPARSGGSRGEGSKGLSTALMWTFPILILLIVGIVYFNNTKDAPETAGTGEETTAQQPADNSTTEPAGEEAADPGTTGGGVQTPGTDTPEGTDATTPPADGTETATPPADNTTPPTEGTETGTAEGTDPAAPGTDEAGQTGEEGTEDTGTAPNTSGSTVVTPAGQEGKTTVFNAQPAQGGTVKVTINASGMSWLEVYRGSTSGEKLYYQNTQEGEALTFDMDAQGLYIKSGYSPVTDIRIDGQPITDGKTTSRFKVNLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0V3</accession>
    <name>A0A011A0V3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flagellar hook-length control protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0097</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282374.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_575982_0_0_9"/>
    <dbReference type="OrthoDB" id="1796543at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021136">
        <property type="entry name" value="Flagellar_hook_control-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038610">
        <property type="entry name" value="FliK-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02120">
        <property type="entry name" value="Flg_hook"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001458330" evidence="2">
        <location>
            <begin position="24"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_hook" evidence="3">
        <location>
            <begin position="329"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="464" mass="49205" checksum="4A7025610DD747E3" modified="2014-06-11" version="1">MGMTIPGMTVGSAAPVTSGKATAASTTGAAAIFGQSLQQLMGGAMTGGNAGEATETPTNPLLAALQQLIAAAGEASGDEGSLDGEEAEKLDAKVDELLDQLDALDEQLTENPELMPMLQSWIQQAQVVLNAQSQGENAQGEGQEAAASALETLASNPATLKFALQDTVTQLVDMQKSGQTAPEMKVQAQRVLAALEQTVKTVEESAKSGVKQTSMQAAEAFRIQDDVQQIVKNDQNAKPATEAQAKSSEQTVVSSKAQTQQQSGAGTQQEDGRNQETTQEFKTQGTITAGELALRTNGTTPAKPVEAVPMHRMAQEVEKLVVDRLEILQKQGFTEAKITLTPDHLGKVDIRITMHAGQLMAHFVTEHAAAKDMLEQQMVQLRGSLQGQGLTVERLEVTQSSSLQSQMDQNGGQQGNGQQQGRRSRSREEGNDDARLTAELGEELGEWLRQKTAAQAGSSFIAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0V8</accession>
    <name>A0A011A0V8_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar motor switch protein FliG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">SacsacDRAFT_0102</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282380.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.103"/>
    <dbReference type="HOGENOM" id="CLU_047835_1_1_9"/>
    <dbReference type="OrthoDB" id="847822at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000090">
        <property type="entry name" value="Flg_Motor_Flig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023087">
        <property type="entry name" value="Flg_Motor_Flig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011002">
        <property type="entry name" value="FliG_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032779">
        <property type="entry name" value="FliG_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028263">
        <property type="entry name" value="FliG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30534">
        <property type="entry name" value="PTHR30534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01706">
        <property type="entry name" value="FliG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14841">
        <property type="entry name" value="FliG_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14842">
        <property type="entry name" value="FliG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003161">
        <property type="entry name" value="FliG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00954">
        <property type="entry name" value="FLGMOTORFLIG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48029">
        <property type="entry name" value="SSF48029"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00207">
        <property type="entry name" value="fliG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliG_N" evidence="12">
        <location>
            <begin position="9"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_M" evidence="11">
        <location>
            <begin position="119"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_C" evidence="10">
        <location>
            <begin position="222"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG83137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="338" mass="37869" checksum="445400745A33EA44" modified="2014-06-11" version="1">MAKASAQTLSGRQKAAILLISLGPEVSAQIFKHLRDEEIEQLTLEIANVRKVDSSEKDSVLAEFHQICLAQEYISQGGINYAKDILQKALGEQKALEVINRLTATLQVRPFDFARKADPSQILNFIQNENAQTIALVLSYLQFEQASIILSSLPQEKQAEVARRIAMMDSTSPEVIAQVERVLEQKLSSTVTQDFATAGGIESIVSILNGVDRGTERTILDSLEIQDPELAEEIKKRMFVFEDIVNIDDRSIQRIIRDVENADLQLALKVASEEVREVVFKNMSKRMADTFREEMEFMGPVRLRDVEEAQTRIVTIIRKLEEAGEIIIARGGGDDIIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0X7</accession>
    <name>A0A011A0X7_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Signal peptidase I</fullName>
            <ecNumber evidence="4 6">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="4 6"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282422.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.122"/>
    <dbReference type="HOGENOM" id="CLU_028723_5_0_9"/>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="7">
        <location>
            <begin position="26"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="206" mass="23198" checksum="978F4E73F024AFF5" modified="2014-06-11" version="1">MEENVNRPAAEEAPNNPKNKVKSETLEWVKAIAIALVLVFVIRWLLFAPYMVDGSSMQPNFHDGERVIVNKILYDIRAPKKDEVIVFKVPSEDNKEFIKRVIALPGDTVKVEGDEVTVNGEVIEEPYIQGVLDQAHANGETYNNNTNFPNATFPDGTVPEGHVFVMGDNRPNSKDSRMIGYVPYSDITGRADLVFWPFSEMHIVNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0Y3</accession>
    <name>A0A011A0Y3_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA-binding protein KhpA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">KH-domain protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">khpA</name>
        <name evidence="3" type="ORF">SacsacDRAFT_0127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms a complex with KhpB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KhpA RNA-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282434.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.127"/>
    <dbReference type="HOGENOM" id="CLU_132074_1_0_9"/>
    <dbReference type="OrthoDB" id="1940160at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00088">
        <property type="entry name" value="UPF0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020627">
        <property type="entry name" value="KhpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34654">
        <property type="entry name" value="PTHR34654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="76" mass="8333" checksum="DFBB6F714B585AAE" modified="2014-06-11" version="1">MEQLVAVIAKALVDHPEDVKVRTIEKESLVVYELSVHPDDIGKIIGKQGRIAKALRTVVTSAAVKLDKRVTVDIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0Z2</accession>
    <name>A0A011A0Z2_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Acyl carrier protein</fullName>
            <shortName evidence="8">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acpP</name>
        <name evidence="12" type="ORF">SacsacDRAFT_0137</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8 10">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282458.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.138"/>
    <dbReference type="HOGENOM" id="CLU_108696_5_3_9"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 8 9" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8 9">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG83172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="77" mass="8520" checksum="DEB03B3F2AE5B554" modified="2014-06-11" version="1">MSDVMERVTRIVVDRLGADEAEVTPTASFKEDLGADSLDVVELVMELEDEFDLEISDEDAEKITTVGDVVSYIQSHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A0Z8</accession>
    <name>A0A011A0Z8_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcription factor FapR</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Fatty acid and phospholipid biosynthesis regulator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fapR</name>
        <name evidence="2" type="ORF">SacsacDRAFT_0142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FapR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282468.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.143"/>
    <dbReference type="HOGENOM" id="CLU_095708_0_0_9"/>
    <dbReference type="OrthoDB" id="1813646at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045717">
        <property type="term" value="P:negative regulation of fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01814">
        <property type="entry name" value="Transcrip_fact_FapR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017275">
        <property type="entry name" value="Transcription_factor_FapR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037733">
        <property type="entry name" value="Transcription_factor_FapR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="190" mass="21890" checksum="8773C719773367EE" modified="2014-06-11" version="1">MERLPKRQRQQRLVELIDENPFVTDRELTRRLKVSIQTIRLDRMELGIPELRERMKLMAERSYDQVRSLAAEEVIGDIIDLQLDRSGISIFEIRDEHVFSRTQIARGHHIFAQANSLAVAVINDEIALTASADLRFVRPIHLGEKCIAKAYVRSSPGKAGRAKVEVLSYVGEEMVFQGNFIIYRSDDKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A116</accession>
    <name>A0A011A116_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative RND superfamily drug exporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">SacsacDRAFT_0162</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282499.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.164"/>
    <dbReference type="HOGENOM" id="CLU_005108_0_0_9"/>
    <dbReference type="OrthoDB" id="149255at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023908">
        <property type="entry name" value="xxxLxxG_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03057">
        <property type="entry name" value="xxxLxxG_by_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="875"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="898"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="934"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="973"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="999"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="901"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EXG83197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="1050" mass="112409" checksum="93C237EF860BF3A2" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A160</accession>
    <name>A0A011A160_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-carboxymuconate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282577.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.216"/>
    <dbReference type="HOGENOM" id="CLU_038716_3_0_9"/>
    <dbReference type="OrthoDB" id="302683at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="352" mass="38334" checksum="021219F79695BBC8" modified="2014-06-11" version="1">MTQVQKMLVFVGSYAEANTSGVYTYEFDEKEGKLSLLDQTSDLKNPTFLNVDVENRHIYAIGETETESGKAGEVMMIQFSEEGTLTRFNRTITTPNTTCHVQRDSENRFLIVSSYHGGMAGLVSLKADGHVGELLDVAEHQSVDGATPRVHSVFFSPDEKFLLVQDLGLDLIRTYSLDREAGKLIPQGDTHAAKGAGPRHLAFHASGKFAFVINELNSTIASYRYDAATGSLSEIEVVPTLPSDYTGENGCSEITVSADGRFVYGGNRGHDSIVVYAFDETSEKLTLVEHVSTEGGHPRHFALTPSGDHALVANRDANNIVVFKVDKATGRLTSTGNSVSVSKPVCVRPYYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A171</accession>
    <name>A0A011A171_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative stress response protein, TerZ-and CABP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0212</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAPAB/TerDEXZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282583.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.222"/>
    <dbReference type="HOGENOM" id="CLU_030559_0_0_9"/>
    <dbReference type="OrthoDB" id="1437267at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06974">
        <property type="entry name" value="TerD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003325">
        <property type="entry name" value="TerD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019303">
        <property type="entry name" value="vWA_TerF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02342">
        <property type="entry name" value="TerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10138">
        <property type="entry name" value="vWA-TerF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="229"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="426" mass="46187" checksum="040D7C525491DC8C" modified="2014-06-11" version="1">MGQQPEVLIQGGNTTLGTSGKAKVILEWTASPSPIDASCFMLGPSGTVSSDAHFIFYNQPRSPLGDVELTASSERASVFEVDLAALKAGHVEKFVFAAVLDGSGTFGDVQGFSVKVECAGRTITCPFAGTDKEAALVLAEIYLYKESVKLRAVGKGFDGGLGPLAKSFGVDVEGDSEQNERADDPSAVAPAASSTVEETPEQPLGRIDLLKKKVAISLEKKQIARQKAKVAVVFDASGSMNKLYKNGTVQRAFERILAIAANMDDDGTLDVWMFALEFVRAAPAHVSDYEGYVNRVYPFKGAGGRNNEPAVMQDVIQKFTVEDSDPSIPVYVVFFSDGGVAETKKISRLLIESSLHPIFWQFVGLGEANYGVLRKLDDLPGRMVDNAGFFALDDIDTVGDEELYDRLFEEFPDWLREVKAKNILRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A175</accession>
    <name>A0A011A175_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolase or acyltransferase of alpha/beta superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506767.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_9_0_9"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="33"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="308" mass="34258" checksum="F8C5ED6E07CACD6B" modified="2014-06-11" version="1">MNNPNKPRSLLPSRQTVDGLHVQLTGTPNSAYPPVVFEHGCGVSSEVWALVCPELANLTQTLVYDRAGYGFSEPGVLPRTSDRCVEDLRKVVERLNLARPFILVGHSLGGFYARLYAERYPEDVAALVLIDASHEDEIRGIFPIPHLKRQKLSVRLYGFAKWVARIGVLPWLAQRHWIPGFGKFVAKLPQASRDAMWERVFSANSMEAAESEYDCFVGETGSVPHSRFARLPLAVVKAGVYLPGRTRKATLRQQVERTLYDTAVKMQHLSEAGRLIEAGGSGHHVQVDKPGTVIGIVKRLLEQTRVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A183</accession>
    <name>A0A011A183_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TVP38/TMEM64 family membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">SacsacDRAFT_0232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282615.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.244"/>
    <dbReference type="HOGENOM" id="CLU_038944_10_0_9"/>
    <dbReference type="OrthoDB" id="1951488at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="PTHR12677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EXG83267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="202" mass="22550" checksum="F733D5797AB950F6" modified="2014-06-11" version="1">MKKWITLTVYAAALLLILIYRHELQALMENVSLPLSTGFALAFLFAFFPVLPYKLLIGSLGFLYGPALGALTAWLAVTTASLLQYTLVRRFFREQGRAALAKFSGLERAGQLMERRPFLVILAARLVPLLPQALVNLYPAFLNIRPIVYIAASALGKIPAMLVFAFVGQNLFTDLPKTMTVLALYGGFLLMVYAVYRFVLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A193</accession>
    <name>A0A011A193_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DnaJ-class molecular chaperone with C-terminal Zn finger domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">SacsacDRAFT_0247</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506773.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="J" evidence="4">
        <location>
            <begin position="5"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="62"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG83282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="312" mass="34205" checksum="9462BC058ABCA3ED" modified="2014-06-11" version="1">MPDKNYYDVLGVDANASQSEIKKAYQKLAKQWHPDVNKAEGAEARFKEIAAAYEILGSEEKRGDYDASRRRSASGFGGAARGRSSGSQEPEFGSGGSNFDWINDLQHEDIFDMFFNERMGGMGGIPGGFGSATAEAGPRRPAQSTLEVTLEQAYKGETVRIELGGKKIGLRLPERSRNGQTVRMTGNGSNGLAVGEELLIVLKIVEHAVYSLEEEDLIAALRIAPWQAALGGQARIVLPDGAAVNMNIPRGIAARRRLRIPRRGLKKSDGTYGDFFAEIEIAIPDPSKEEEELYRRLEAFSKFNPQLAKRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A1B3</accession>
    <name>A0A011A1B3_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tissue inhibitor of metalloproteinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506777.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1325553_0_0_9"/>
    <dbReference type="OrthoDB" id="1571962at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008191">
        <property type="term" value="F:metalloendopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001820">
        <property type="entry name" value="TIMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008993">
        <property type="entry name" value="TIMP-like_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00965">
        <property type="entry name" value="TIMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50242">
        <property type="entry name" value="SSF50242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="207" mass="21923" checksum="898B402A441630CF" modified="2014-06-11" version="1">MHASRRRGVLSLLLILMITVTTLGAGLTIAAKPAIACSCAMSDTNSSMAYADRIFAGTVAERRETPPDLSGLRSSADPVYYVFEVDQAWKGEVYETTTLYSAAFSASCGMEFVQGEKYLVFAKQGNGMPTTTLCSGNEAYQGTTDPAAVKKLGEPIELLAGSSPGTPSGDWGTPPGASFILWGFGGFFALLIAAFIGIKAVRAKRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011A1C0</accession>
    <name>A0A011A1C0_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polyketide cyclase/dehydrase and lipid transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">SacsacDRAFT_0283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.300"/>
    <dbReference type="HOGENOM" id="CLU_112936_0_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EXG83317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="176" mass="20191" checksum="F9EFB61DE017A7E3" modified="2014-06-11" version="1">MSVIGGLVSIVAITKEIMIHAPIEVCFDAARDVGLHPQTVWPRTRERTLPGGRLEGLMEKNEIVVFEAVHFGIRQQLTSLVEELDKPYLFVDRMQKGAFRHMMHRHEFERCEEGTLVRDILEFASPFGPAGRLFDALVLRRYMLSFINYRQRQLKSILENGYATDGQRSDSSTSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM53</accession>
    <name>A0A011AM53_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="8">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">argS</name>
        <name evidence="12" type="ORF">SacsacDRAFT_0016</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="8"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506749.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.16"/>
    <dbReference type="HOGENOM" id="CLU_006406_6_1_9"/>
    <dbReference type="OrthoDB" id="1146366at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="11">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="10">
        <location>
            <begin position="440"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG83051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="567" mass="63384" checksum="25917D4D421556F6" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM64</accession>
    <name>A0A011AM64_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribonuclease Y</fullName>
            <shortName evidence="7">RNase Y</shortName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rny</name>
        <name evidence="10" type="ORF">SacsacDRAFT_0031</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Endoribonuclease that initiates mRNA decay.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RNase Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282207.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.31"/>
    <dbReference type="HOGENOM" id="CLU_028328_1_0_9"/>
    <dbReference type="OrthoDB" id="1012190at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00335">
        <property type="entry name" value="RNase_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017705">
        <property type="entry name" value="Ribonuclease_Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022711">
        <property type="entry name" value="RNase_Y_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF15">
        <property type="entry name" value="PTHR12826:SF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12072">
        <property type="entry name" value="RNase_Y_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03319">
        <property type="entry name" value="RNase_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="9">
        <location>
            <begin position="330"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="27"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG83066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="514" mass="57990" checksum="C6999B107D1E202F" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM76</accession>
    <name>A0A011AM76_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="12">ASA dehydrogenase</shortName>
            <shortName evidence="12">ASADH</shortName>
            <ecNumber evidence="7 12">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">asd</name>
        <name evidence="14" type="ORF">SacsacDRAFT_0046</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7 12"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282251.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.46"/>
    <dbReference type="HOGENOM" id="CLU_049966_0_1_9"/>
    <dbReference type="OrthoDB" id="1799040at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005986">
        <property type="entry name" value="Asp_semialdehyde_DH_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01296">
        <property type="entry name" value="asd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="13">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="12">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="14"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="42"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="161"/>
            <end position="162"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EXG83081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="347" mass="37503" checksum="B296ABF8A5D72FB7" modified="2014-06-11" version="1">MSNETFNVAVVGATGAVGEQILRLLEERNFPIKTLKLLSSARSAGSKLKFKGEEVTVEEAKPESFEGVQIALFSAGGDVSKVLIPEAIKHGTVCIDNTSAFRMDPTAPLVVPEVNEEKIFEHNGVIANPNCSTIQMVAALKPLQDRYGLKRIIVSTYQAVSGSGAKAIAELNRQTKAIVNGEPVNPDVLPVASLPVKHQIAFNAVPQIDKFTENGFTYEEMKMINETKKIMGDESIQVTATCVRIPVVYGHSESVYVELGSEYDLQEVRSLLENAPGITVVDDPANQAYPLATDAAGKNDVFVGRLRRDLDSPTGLNLWIVSDNLLKGAAWNAVQIAEIIAARSQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM81</accession>
    <name>A0A011AM81_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">Riboflavin kinase</fullName>
                <ecNumber evidence="11">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">FMN adenylyltransferase</fullName>
                <ecNumber evidence="11">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="ORF">SacsacDRAFT_0051</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ribF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="11"/>
    <dbReference type="EC" id="2.7.7.2" evidence="11"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282262.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.51"/>
    <dbReference type="HOGENOM" id="CLU_048437_0_2_9"/>
    <dbReference type="OrthoDB" id="1504821at2"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 11" id="KW-0288">FMN</keyword>
    <keyword evidence="11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="12">
        <location>
            <begin position="186"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG83086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="313" mass="34260" checksum="E3AEA5D9B1A5A090" modified="2014-06-11" version="1">MKTITLTYPLIGVGETIPVQRQILAIGQFDGLHLGHVSVIQRALELGRSLQLPVAVLTFHPHPKEVMGKGDYEGYLTPLRDKESILEELGVDYMYVGEFTPEFSKVPPSDFVTKVLLPLQVATAVVGFDFRFGFMGEGTAEAIHPLSGGKIDVETVAPFLLEEEKVGSSGIRAALKLGDAEKAHRLLGRPYRVRGTVVGGDKRGRTIGFPTANVDPSGHYVTPAKGVYAVRFGLEGEVYGGVMNVGVKPTFTDGSIKPTFETHLFDFDRSIYGEDVWIDLVQYIRPERKFSGIDELVAQIAKDADEARGILNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AM91</accession>
    <name>A0A011AM91_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proline--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="8">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proS</name>
        <name evidence="10" type="ORF">SacsacDRAFT_0061</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="8"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282287.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.61"/>
    <dbReference type="HOGENOM" id="CLU_001882_4_2_9"/>
    <dbReference type="OrthoDB" id="665824at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PTHR43382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="SSF64586"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="41"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EXG83096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="485" mass="55626" checksum="B1D87B6645EB2B48" modified="2014-06-11" version="1">MASDKQDKQFVTEITPQSEDFSRWYIDVIKKAELMDYAPVRGCIVFRPEGYAIWENIQQEMDRRFKETGHRNAYFPMLIPESFFQKEKEHIEGFNPELPFVTEAGGDILEERLAVRPTSETMFGHMYSKWIKSYRDLPVLINQWANVMRWEKRTMPFLRTSEFLWQEGHTAHEDEKDAREETMRMLELYRDFVEDFLAMPVIMGQKTPSEKFAGAVDTYSIEAMMKDGKAVQAGTSHYMGTNFAKAFEIQYLNRDNELEFTHTTSWGTSTRLIGSMIMAHGDDRGLVIPPKVAPTQVILIPIGPPKMRDMVIERADALYAELKAAGIRVSMDDRADVRPGWKFNEYEMRGVPVRIEIGPRDIENGVCLLASRLGGDKLTVQLDNVVNDVKQLLDDVQKGMYERALEFRASHFHSVDNLDEMRAQMEEKRGFFLAGWCGSEACEDTVRAETGATSRNIPFDPQEHKTTCVACGEAAKHTVVFAKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMB1</accession>
    <name>A0A011AMB1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATPase involved in chromosome partitioning</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0081</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282337.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.82"/>
    <dbReference type="HOGENOM" id="CLU_037612_0_0_9"/>
    <dbReference type="OrthoDB" id="1370117at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02038">
        <property type="entry name" value="FlhG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033875">
        <property type="entry name" value="FlhG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025501">
        <property type="entry name" value="MinD_FleN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003092">
        <property type="entry name" value="MinD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="3">
        <location>
            <begin position="34"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="298" mass="32943" checksum="B1C1178AFB503276" modified="2014-06-11" version="1">MSDQAAALRELISSLGTDPSRQRDSSGTQEKTAHIIAVTSGKGGVGKSNFTLNFALELQKLGRKVLVFDADIGMANIDVLMGVRSQYNLFHLLNREKSMSEIIQSGPNSLPFIAGGSGLTELFSLSEEDLLYFTRQIEEIAHDMDYILFDTGAGLSKETIRFITAADECIVVTTPEPTAITDAYALVKVVHDLEHAALFRLVVNRAVDRREAQQTADKIRLVAEKFLHLDIPVLGHVSDDPHVSQAVKKQTPFSIRFPNSQASKDIQELASRYAQQSLQVRADSPKGFKSFVRKLLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMC1</accession>
    <name>A0A011AMC1_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar motor switch protein FliM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">SacsacDRAFT_0091</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19268</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282359.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.92"/>
    <dbReference type="HOGENOM" id="CLU_052646_0_0_9"/>
    <dbReference type="OrthoDB" id="1748746at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17908">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001689">
        <property type="entry name" value="Flag_FliM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02154">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002888">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00955">
        <property type="entry name" value="FLGMOTORFLIM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01397">
        <property type="entry name" value="fliM_switch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="10">
        <location>
            <begin position="253"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG83126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="332" mass="37520" checksum="1C382DB372CB90A6" modified="2014-06-11" version="1">MVDVLSQNEIDALLAALSSGEMDAEELKKEETQRKIRSYDFKRAVRFSKDHIRSLTRIHENFARNLTTYFSAQLRTFVQISVVQVEQLPYDEFIRSIPKMTVLNIFEAEPLEGRMVLEVHPNIAYAMVDRMLGGSGTAPLKPAALTEIETIIMERIFSRALENLQDAWKTVYDLSPRMEALETNPQFMQIVSPNETIALISLSTKIGDTSGMINLCIPHVVIEPIMSKLSVHHWFVSQKKARAPEELEALRQRVTRAELPVIAELGQSQLTIREFLSLAPGDVITLNKATEEGLAIRIGERLKFIGSPGMIKDRIAVQIDEIVDEGVEEFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-06-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMC6</accession>
    <name>A0A011AMC6_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Basal-body rod modification protein FlgD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">SacsacDRAFT_0096</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for flagellar hook formation. May act as a scaffolding protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the FlgD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506753.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.97"/>
    <dbReference type="HOGENOM" id="CLU_047535_1_0_9"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005648">
        <property type="entry name" value="FlgD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03963">
        <property type="entry name" value="FlgD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="141"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="141"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EXG83131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="206" mass="21650" checksum="9F732AAA2D8A80E7" modified="2014-06-11" version="1">MANSNVSTTNIWPNYSTQNVQKAAAKKTDDAATMGKDQFMTILIAQLKNQDPLAPMDNSQFTAQMAQFSSLEQLMNMSTQLTQMNSSMGTASQLIGQKITWYDSETANYLTGNVASVLQKDGKMYAAVGEYLVPTSDITMVEPAGTSETPTAGTAPAADTTTETPKSETNTDAAAQQAQASGTQTSQSSTEEAAGTSESGNDGGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AME3</accession>
    <name>A0A011AME3_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA topoisomerase 1</fullName>
            <ecNumber evidence="10">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">topA</name>
        <name evidence="13" type="ORF">SacsacDRAFT_0111</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="10"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282401.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.111"/>
    <dbReference type="HOGENOM" id="CLU_002929_4_3_9"/>
    <dbReference type="OrthoDB" id="223233at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="12">
        <location>
            <begin position="3"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="10">
        <location>
            <begin position="163"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EXG83146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="699" mass="78895" checksum="EAEB124E5649D8E3" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMP2</accession>
    <name>A0A011AMP2_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">SacsacDRAFT_0206</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506764.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.215"/>
    <dbReference type="HOGENOM" id="CLU_000445_114_57_9"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="7"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="10">
        <location>
            <begin position="81"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="153"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EXG83241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="385" mass="43258" checksum="BDEEE71BD2D62306" modified="2014-06-11" version="1">MNDLPASKPDWPHIIGELRSSVTITDATDPKQPLIFVNEYFLQLTGYSREEVIGRNCRFLQGADTRSETAREIREALSKCMPVRTEILNYRRDGSTFWNELNIDPIFDAEGRCVLFVGLQYDVTDRKLLEEEATHAARSAHSQSRALMEFMGKLNHEMRNNMNGMLGMIDVVLMDESLPEDVREYLEIAKGSGDTLLNMANDALDFAGAADGRIRLEHIEFNPKHVLDSIVKTHRLRAEEKGLNLILDTQSLHSQRLYGDPHRLRQVLDNLIGNALKFTQSGSITLIAEEMPADRSSGLTPMRFSVRDTGIGIPEEHMDKLFKAFSQTDASHARVYGGSGLGLKICEELVQLMGGTIFAESRQGEGSTFRVELPFSPEDPHHLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMS2</accession>
    <name>A0A011AMS2_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282598.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.232"/>
    <dbReference type="HOGENOM" id="CLU_029469_2_1_9"/>
    <dbReference type="OrthoDB" id="275025at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="193"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="453" mass="49620" checksum="DD409718740E9512" modified="2014-06-11" version="1">MNNYQTYFEQNRDKHLGELKEWLSIPSISALSAHKEDVLRAAEWLKDALVRAGLENVTLHETAGHPILTADHLHAEGAPTLLIYGHYDVQPVDPLNLWDTPPFEPNEREGKLYARGATDDKGQVFLHVKALEAILAQEGKLPVNVKLCIEGEEEVSSPNLVEFLDANAAALAADAVVISDTSLLERGKPAISTGLRGLCSLEIALNTANTDLHSGSFGGGVPNALHAIVSLLNSLHDEKTGRVLVEGFYDDVLPLTDELRGELVKMQYDEEKLRNDLGLEALFGEEGYSFLERTGVRPTLELNGVYGGFQGEGTKTVIPKEAHAKITCRLVANQDPQDILNKIERHLHARTPVGAKLTLVPGEKAFAFNIDPTHPFLQKAADAYEAVYGTRALFTKDGGSIPIIEAFSRVLEAPVVLMGFGLPDENLHAPNEHFNLENFDKGLLTLVHYLKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMT2</accession>
    <name>A0A011AMT2_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ferredoxin--NADP reductase</fullName>
            <shortName evidence="2">FNR</shortName>
            <shortName evidence="2">Fd-NADP(+) reductase</shortName>
            <ecNumber evidence="2">1.18.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">SacsacDRAFT_0236</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 19268</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:20125"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferredoxin--NADP reductase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="2"/>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282618.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.248"/>
    <dbReference type="HOGENOM" id="CLU_031864_5_5_9"/>
    <dbReference type="OrthoDB" id="692968at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01685">
        <property type="entry name" value="FENR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022890">
        <property type="entry name" value="Fd--NADP_Rdtase_type_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="7"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EXG83271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="345" mass="37994" checksum="8F3F5321921CAD31" modified="2014-06-11" version="1">MEELELYDVTIIGGGPAGMYAAFYSGMRDMKTKVIEAKDELGGRMLIYPEKMIWDVGGVTPVLCENLVSGLKQQARTFDPTVVLGQQVTGLARREDGTFVLTTASGERHWTKTIVLAIGYGILKMAKLEIEGADRYEVTNLHYTVQEMDVFRGRNVLISGGGNSAVDWANELEPVAAHVTIVHRRDKFWGHEKNVLKMQESSVDVRSLHAVSELHSSDGRRIDEVSIKHMESEQVERLKVDAVIVNHGLTSDYGPLKEWGLHMEDSVAVVDGKLKTNIPGIFAAGDFASYDSKLRLIAGAFTDAALAVNSAKLYIDPEAAKVAYVSSHNDRFKEKNKALGVAVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMT9</accession>
    <name>A0A011AMT9_9BACL</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">clpB</name>
        <name evidence="12" type="ORF">SacsacDRAFT_0246</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 19268</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282636.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.258"/>
    <dbReference type="HOGENOM" id="CLU_005070_4_2_9"/>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="11">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="412"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EXG83281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="886" mass="99691" checksum="4AF9990AD08578EA" modified="2014-06-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMV1</accession>
    <name>A0A011AMV1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative domain HDIG-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_037282658.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.277"/>
    <dbReference type="HOGENOM" id="CLU_000445_92_1_9"/>
    <dbReference type="OrthoDB" id="1094814at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="105"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="342" mass="38612" checksum="D70072D7C1FD600B" modified="2014-06-11" version="1">MRIHVTDLQQGDMLKEDAFNPAGLHVLPRGTVVKIEETDLLNRHKIDYVEIEPRGSETGPGVLSAVMQSHIELAIRGYQSIFLEALTSGKFEESTVDLQLEPLLRTVDEHRDIVSLLLVLEREDVSLYNHSMQVGMLSYYMATWLGYSREECYAVSKAGYLHDIGKSKISPTIRNRTDYLTEYDMQELRKHAKLGHDVIKNSMNDETTALVALQHHEREDGSGYPQGLTKPDIHPYSQIVAVADTYLRLSEGKKGEPKRPLLDILREVSELGFGKLNEKPVQALVQHLMSNLIGKNVRLSSGDTGTIILNNPSDIFKPLVRVGDQFHDLSRERNLAVEEVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-06-11" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A011AMX1</accession>
    <name>A0A011AMX1_9BACL</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">SacsacDRAFT_0292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Saccharibacillus sacchari DSM 19268</name>
        <dbReference type="NCBI Taxonomy" id="915437"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Firmicutes</taxon>
            <taxon>Bacilli</taxon>
            <taxon>Bacillales</taxon>
            <taxon>Paenibacillaceae</taxon>
            <taxon>Saccharibacillus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-07" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Anderson I."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 19268</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JFBU01000001">
        <property type="protein sequence ID" value="EXG83326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051506781.1">
        <property type="nucleotide sequence ID" value="NZ_KK073875.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|915437.3.peg.309"/>
    <dbReference type="HOGENOM" id="CLU_013985_34_9_9"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000053380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EXG83326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000053380"/>
        </source>
    </evidence>
    <sequence length="158" mass="17653" checksum="EFDB5B51AB88CE29" modified="2014-06-11" version="1">MEKQHEEIVIRAASVTDMDQLAPLFDAYRVFYEQPSDLEAAKHFLTDRLGQLQSVVLLAEEKATSRAAGFTQLYPVFSSVSMQRSWILNDLYVDPQFRGLGAGSALLDAAARHARLTGAKGIALSTAPTNKTAQRLYESKGYKLDDEYLNYFLTLSKK</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>