<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="http://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
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<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>W9DVW5</accession>
    <name>W9DVW5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TetR_C_31 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260279.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.9"/>
    <dbReference type="HOGENOM" id="CLU_069356_21_0_11"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041583">
        <property type="entry name" value="TetR_C_31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17940">
        <property type="entry name" value="TetR_C_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TetR_C_31" evidence="1">
        <location>
            <begin position="87"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA70989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="211" mass="21911" checksum="D5FBDE5F17B626C9" modified="2014-05-14" version="1">MTATPRSRAEIVGDTAIAVLAAQGARGLTHRAVDRAAGLPPGSTSNHARTREALLTCALTRITELEAADAAAATAGQPVFDTGGDVRTALAAPIAAMLYRGLSRGRTRLLARYELALESTRRPALRALYDEASLPFRGPVAAMLAASGSAEPQRHAKMLIAWCEGVQFDAIAGAGAATPPAEAELRTGLEELLRGMLGTGRESSAIQGVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9DVX1</accession>
    <name>W9DVX1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_9_4_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA70994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="225" mass="23597" checksum="4F909CB7E5A9DDC7" modified="2014-05-14" version="1">MPHTVLDEVPTAAPEYAGLLVDWGGVMTTDVFASFAAFAEAEGLAADAVARLLRHDAGARALLDGLETGAADPAEFERGLAALLGVAADGLIRRLMAGVRVDERMIAAVRAARQAGAATGLVSNSWGPSGYPRELIAEMFDGVVISGEVGVRKPRPEIYRLGADAIGVPPAQCVFVDDLRGNLRPAEELGMTVIHHTSADETASRLAALFAAKRPQPGHHQERAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9DVX6</accession>
    <name>W9DVX6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IPT/TIG domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.20"/>
    <dbReference type="HOGENOM" id="CLU_1479092_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IPT/TIG" evidence="1">
        <location>
            <begin position="58"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA70999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="182" mass="18951" checksum="A5A5016782A1D337" modified="2014-05-14" version="1">MPRHGGRTAALVLLRADDGRVSRNTRATAVRAGVRLFAGLCLLAGVSAAGPAEASSHPVIRSVSPATVDTDGGTVTVSGYGFTGTDSVKLLSLPSSTVTARPAYVYYKVISDDTLRLTVPTHTAGTVWISITTASGSNTYSSHDRLQFSENASTSNPPGKDTLGALLLAMLIGMIFGRNRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9DVY7</accession>
    <name>W9DVY7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260311.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1507547_0_0_11"/>
    <dbReference type="OrthoDB" id="2079978at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919850" evidence="1">
        <location>
            <begin position="27"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="178" mass="17168" checksum="4BA6CB3FE15C7E84" modified="2014-05-14" version="1">MNGKRTAIALGGSVLATLCAAGPALASGGGGVNNSIIIQPNPVAPGGTISVFDGGNCDYPSTGTVTFQTGSVPGIPAITIGPLKSMIGGTGQVPRNIAPGSYQVTLICTSNSGRKQGPFYGTLVVANGASTGLTPIGGAGTGDGASLTTPGGLAEGIGLVASGGAAWFLLRRRAARVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-06-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>W9DVZ4</accession>
    <name>W9DVZ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transglycosylase family protein,LysM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0032</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450062.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.35"/>
    <dbReference type="HOGENOM" id="CLU_083020_0_0_11"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919852" evidence="2">
        <location>
            <begin position="38"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="78"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="288" mass="29399" checksum="78682683A0AC6DB5" modified="2014-05-14" version="1">MSSHRKPRLSFVRNRARALTLCAATFGTAALPGIASAATAAPATATVPQATTAHSVTVHAVAVSDSTGSKSSSSTKQQVHTVVAGDTLFGIAKAALGDGYDYPQIYKLNKGKAQSDGGKLTDPDLIEIGWKIALPSGSKASASSSSSSSSSSSSSSSASSSSSSSSSSSSSSGYADDLDGWINQAISILSAHGYSVTYNAIYQTAMNESSGNPNAENDWDSNAAAGTPSIGLMQVIQPTFDAYALSGYDDIWNPVDNIIAAVIYAQDTYGGLDNVVAERCGGSCWSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW00</accession>
    <name>W9DW00_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ActroDRAFT_0037</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 44927</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260323.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.40"/>
    <dbReference type="HOGENOM" id="CLU_007946_16_0_11"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ETA71019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="552" mass="58651" checksum="E79DEE23E6B1B43E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW33</accession>
    <name>W9DW33_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ActroDRAFT_0042</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_3_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017881">
        <property type="entry name" value="NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012748">
        <property type="entry name" value="Rieske-like_NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40562">
        <property type="entry name" value="PTHR40562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13806">
        <property type="entry name" value="Rieske_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="26"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ETA71024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="142" mass="14729" checksum="FE2994BF6DDBE69A" modified="2014-05-14" version="1">MTIEMDTAEMDTAVAFAADTPPGPAARVCRYEDLIAGRGVAVLLPDMTQAAVFRTFDGRLFGVGNLDPATGAHVISRGLTGSRDGAPTVASPMLKHVYDLATGQCVDGPAGREPYALAVFPVRCDEGVVYIHTAPPIVAGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW53</accession>
    <name>W9DW53_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-galactosidase</fullName>
            <ecNumber evidence="5">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ActroDRAFT_0059</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 44927</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="5"/>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.63"/>
    <dbReference type="HOGENOM" id="CLU_395755_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052692">
        <property type="term" value="F:raffinose alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001919">
        <property type="entry name" value="CBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012291">
        <property type="entry name" value="CBM2_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000111">
        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="PTHR11452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00553">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SMART" id="SM00637">
        <property type="entry name" value="CBD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00512">
        <property type="entry name" value="ALPHA_GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51173">
        <property type="entry name" value="CBM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919342" description="Alpha-galactosidase" evidence="7">
        <location>
            <begin position="39"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="CBM2" evidence="8">
        <location>
            <begin position="451"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="401"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ETA71039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="559" mass="57394" checksum="C5D58D0237BCD8B4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW64</accession>
    <name>W9DW64_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Family 31 glycosyl hydrolase, alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260367.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.78"/>
    <dbReference type="HOGENOM" id="CLU_000631_7_3_11"/>
    <dbReference type="OrthoDB" id="469334at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gal_mutarotas_2" evidence="3">
        <location>
            <begin position="135"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="667" mass="73481" checksum="36617D91BF6338D6" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW72</accession>
    <name>W9DW72_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TIGR01777 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0085</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260384.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.89"/>
    <dbReference type="HOGENOM" id="CLU_047373_0_0_11"/>
    <dbReference type="OrthoDB" id="1566711at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013549">
        <property type="entry name" value="DUF1731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010099">
        <property type="entry name" value="SDR39U1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08338">
        <property type="entry name" value="DUF1731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01777">
        <property type="entry name" value="yfcH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1731" evidence="3">
        <location>
            <begin position="283"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="324" mass="35704" checksum="FA49868D74A77725" modified="2014-05-14" version="1">MKVVIPGGTGQVGTLLRRSLAAQGHDVVILTRQPDRTAQATRTARTHEVAWDGRNLGAWTRELEGADAVINLAGRSVSCRYNEANLQAMMDSRVHSAEVIGEAIARCDAPPAIWLQASTATIYAHRFDAPNDEATGVIGGNEAGVPDYWEYSVRIARAWEQAQREADTPGTRRVALRSAMVMSPDRAGIFDYLSWLARLGLGGPVAGGAQYVSWIHEHDFVRAVCHLIADDRLDGPVNLAAPGPLPQREFMRILRKAWRRPVGLPATEWMAQVGAFVLRSDVELLLKSRRVVPTRLLEAGFAFDYERWPAAADELVARRRHADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW75</accession>
    <name>W9DW75_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260390.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124855_1_0_11"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="170" mass="17319" checksum="E51B0D289DA91153" modified="2014-05-14" version="1">MPILTAAVIVVGVLCVLNLILVDAVIRRLREVSSRLGRDTEKLLPIGSAIGEVPADNAALKHGTKIVAMMSTNCSACMSALDATVGYARNLPGGPADILVAVQGEGGHLDELTAALGDVTTLVTGQAATDLVAALQGRAFPTFYLLEDGRIKAAGHTPLALPTPAAVAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW88</accession>
    <name>W9DW88_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative permease, DMT superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.110"/>
    <dbReference type="HOGENOM" id="CLU_033863_2_2_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="3"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="135"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="315" mass="32598" checksum="5A49BD68B3BE8CFD" modified="2014-05-14" version="1">MTAIAPAVWGTTYIVTTQFLPGGHPLFAGLMRSLPAGIIALICSRALPHGSWWWKALVLGTLNIGAFFPLLFLTAQRLPGGVAATLGATQPIIVAVLVVLVLRERFSVWRVGWGAVGVTGVGMAVLGPDAALDPTGVLAGMAGAASMALGVVLTKRWGRPEGVSALGLAGWQLTAGGLVLLIPTFAIEGVPAHIDGRGIAGYLWLGLIGGLLTYTIWFSGIRRLPVTATALLSPLSPLIAAALGAIFLGQSLNLIQLAGFVLAVAAMLAGQLTPRAATGGRDVRAQALLETDMRTLTSPSPCCCRDWCRRGDKPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW94</accession>
    <name>W9DW94_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Metal-binding protein, terpene synthase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260409.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.116"/>
    <dbReference type="HOGENOM" id="CLU_791388_0_0_11"/>
    <dbReference type="OrthoDB" id="1869158at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="350" mass="39298" checksum="7609C54B68BF80FB" modified="2014-05-14" version="1">MSATEITHLFDLPELQLIPGERAAPWGPQLDASLIAFVRATGLLTTETALDYYTTQHFGTMCAYVVPGAVTQARREIYGKLMAWFFIYDDWAEQLGRHLLPEDVAGMVDDIQTWFADDEDDVRRFDLPAARSMRTIWAQIREDTSPQWRDRLREELGMYLRTAVEEARLVRSGRVNPLGAASELRPLASAARPVYTMAEYAYGIELTPETVRHPLLRKADSVGTAAIAYANDIIGLKADLLRGIRDNLVLSLQHEHGGTLQANVERAAAKFHQKAAEFLDVQEQFRSGSGLCDATIAGRADVATYLQILEDWLFEGVKWQLRETDRYDTTVRLTDRENPNQLLLLSGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWA2</accession>
    <name>W9DWA2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.128"/>
    <dbReference type="HOGENOM" id="CLU_073850_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="224"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="355" mass="38206" checksum="5F3CD4C3F61FDA17" modified="2014-05-14" version="1">MPRQVPGSTSASSRFAESRVWSRYHPRMTANRSAAALSGLARVMAHCGGSPMQAIQYINGAIASAPEDPEPYAILADLWKEQRAAVAGLLKGADSPGAILVHSYISFLENDMDDAAMAIGGVTGARPTVAWADAPWFSDARFLDAVSADALAEAVMRTMDFGHDLDTEDMRKRLRPWFRAIDVVCAREPLPEAMAKMAIFLRASGRTDASFALCDRADAVEPIMLTETVRAGTWRRLGDSDKAAAAFQRALVLDPANWSLYLDLADIRAGQGDFASAVQLVEQGLEHEPTEPTLRAAGAAYRTRITGSPDGLRELIALAPQLPNGSYRGLLIDLACGNAALPAELVAEARRLKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWA7</accession>
    <name>W9DWA7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable 2-phosphosulfolactate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ActroDRAFT_0126</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 44927</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23416"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15597"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58738"/>
            <dbReference type="EC" id="3.1.3.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ComB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.71" evidence="3"/>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.132"/>
    <dbReference type="HOGENOM" id="CLU_070028_1_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050532">
        <property type="term" value="F:2-phosphosulfolactate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005238">
        <property type="entry name" value="ComB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036702">
        <property type="entry name" value="ComB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37311">
        <property type="entry name" value="PTHR37311"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04029">
        <property type="entry name" value="2-ph_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142823">
        <property type="entry name" value="SSF142823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ETA71104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="229" mass="24094" checksum="982792C484EC60FA" modified="2014-05-14" version="1">MRDHGRMDARFLGIAELVETPSVAVVVDVMRAFTVAAWAFGQGAEKIVLAESLQDALALKAGRPDWVTLKDGPPAPGFDAVNSPGLLRSLDLGGRTVVQKTTAGTVGALAVKEASLVLCASFVVAEATARLLRTRGGDGVTFVVTGEDGQADEDLACAQYIARRAMAAETDAAGFLRRAAESRAAAELATGVRQGVHPDDVELCLELDRFPFAMVATLESSLMVLRPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWB3</accession>
    <name>W9DWB3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260436.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.145"/>
    <dbReference type="HOGENOM" id="CLU_315609_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="384"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="494"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="548"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="798"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="840"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="885"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="925" mass="93001" checksum="CD1A1DE2BA63A801" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWC2</accession>
    <name>W9DWC2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PAS domain S-box</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ActroDRAFT_0150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260451.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.157"/>
    <dbReference type="HOGENOM" id="CLU_000445_82_3_11"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="362"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="640"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="765"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="842"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ETA71124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="1387" mass="150472" checksum="A687068F2F732534" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWD0</accession>
    <name>W9DWD0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase, histidine kinase/DNA gyrase B/HSP90-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090336_22_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="45"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="167" mass="17933" checksum="24F4C4FD19B98D73" modified="2014-05-14" version="1">MPSQRMGSSTPVFRSADGPTKRTTDRTQATVGETLHVPAWHMRGDANSIRRARERAHDFLNGLRPRISSEEEQSTLLAVSELVTNAVCHTPGSCALNMTVEDGHVCIAVSDTSRSLPSPRAPEYDGEGGFGLHLLALLAGSLETEVHPHGKTVVARIAVGDTTVRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWD4</accession>
    <name>W9DWD4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.174"/>
    <dbReference type="HOGENOM" id="CLU_063440_10_1_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="2">
        <location>
            <begin position="14"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="101" mass="10824" checksum="29212E7E9CA376DC" modified="2014-05-14" version="1">MLQALAAEPSKWRYGYELGREVGLKAGSLYPILIRLDDRGMVEAGWEDEPAPGRPPRHLYRLTAVGQVLAAELARPAPEGSPAASAPEADGRGRATLCGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWF4</accession>
    <name>W9DWF4_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha-L-rhamnosidase</fullName>
            <ecNumber evidence="2">3.2.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ActroDRAFT_0186</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 44927</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.</text>
            <dbReference type="EC" id="3.2.1.40"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.40" evidence="2"/>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450099.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.194"/>
    <dbReference type="HOGENOM" id="CLU_002926_0_0_11"/>
    <dbReference type="OrthoDB" id="170130at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030596">
        <property type="term" value="F:alpha-L-rhamnosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016007">
        <property type="entry name" value="Alpha_rhamnosid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035398">
        <property type="entry name" value="Bac_rhamnosid_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013737">
        <property type="entry name" value="Bac_rhamnosid_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008902">
        <property type="entry name" value="Rhamnosid_concanavalin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05592">
        <property type="entry name" value="Bac_rhamnosid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17390">
        <property type="entry name" value="Bac_rhamnosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08531">
        <property type="entry name" value="Bac_rhamnosid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010631">
        <property type="entry name" value="A-rhamnsds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_rhamnosid_N" evidence="5">
        <location>
            <begin position="143"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_rhamnosid" evidence="4">
        <location>
            <begin position="325"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_rhamnosid6H" evidence="6">
        <location>
            <begin position="428"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_rhamnosid_C" evidence="7">
        <location>
            <begin position="781"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ETA71159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="876" mass="96343" checksum="9373FCC2965A6428" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWF7</accession>
    <name>W9DWF7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.201"/>
    <dbReference type="HOGENOM" id="CLU_1559675_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="171" mass="18212" checksum="A4DA9515D57318D3" modified="2014-05-14" version="1">MANRPAAVKSALKSQVIETPSWGYGNSGTRFRVFPQAGVPRDPFEKLADAAAVHAVTGVAAPVSLHIPRDRVADYGKLADHAAGLGVRVGMINSNTFQDEDCKLGSVCHPDVGVRRKVTPASANGPRPRLGSQTGIEPQLRRDKNAGSHPGCHGADRRRAALHVPAWSRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWG6</accession>
    <name>W9DWG6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LamGL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ActroDRAFT_0206</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260507.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.212"/>
    <dbReference type="HOGENOM" id="CLU_254785_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919349" description="LamGL domain-containing protein" evidence="3">
        <location>
            <begin position="33"/>
            <end position="1725"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="1565"/>
            <end position="1711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ETA71174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="1725" mass="174910" checksum="98B02A474F07C54E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>W9DYV2</accession>
    <name>W9DYV2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450059.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.24"/>
    <dbReference type="HOGENOM" id="CLU_156623_0_2_11"/>
    <dbReference type="OrthoDB" id="2101132at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="86" mass="9169" checksum="66BD69536A2B56BF" modified="2014-05-14" version="1">MTERKSILLRLDPAVHEALSRWAADELRSTTAQIEFLLRQSLARAGRLPGELGGLPRRGRPPGRGEAADGAADGAATEAEEPPSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9DYW2</accession>
    <name>W9DYW2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolase or acyltransferase of alpha/beta superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450061.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.34"/>
    <dbReference type="HOGENOM" id="CLU_020336_7_3_11"/>
    <dbReference type="OrthoDB" id="1439833at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="38"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="289" mass="30750" checksum="BA5E1A83379A5D29" modified="2014-05-14" version="1">MSDTQGDRLATGGWHRRAVEVGGLTFDLAEQGPADGRPVLLLHGFPQTHRAYDALAAVLAADGANLRLIALDQRGYSPGARPADPGAYTLPELAGDAAGILEALHLSAVDVVGHDWGSLVGWFLAAHYPDRVRTFTAVSVPHPAAFAAALAASAQQRRMSSYVSLFRDPAKAARVLLEDDARRLRALYRPLDDRAAAPHLAALSDPVALTAALSWYQATKFGEGAHTPTVDVPVTYVWSTADAAISRDAAERCVEHVAGPYRFVELEGISHWIPDEAPEALAAALPFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>W9DYW7</accession>
    <name>W9DYW7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">OmpR/PhoB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450063.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.39"/>
    <dbReference type="HOGENOM" id="CLU_037518_1_0_11"/>
    <dbReference type="OrthoDB" id="685227at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="246"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="405" mass="42950" checksum="524B7B7AF90F7B44" modified="2014-05-14" version="1">MSGDWLAETGADPAASAREIARARDAFLSGTPRSGPGSGECAIRDVVARSWERSARARVDPAKDPPVTLAGAELDAYRRTHPLAEVIDLLRELVGSVAEDGRHLMAVSDASGRLLWVEGHAAARRRAEAMNFVEGAVWDESHAGTNAPGTALALDHAVQIFSAEHFRPTVQAWTCAAAPIHDPATGRILGIVDITGGHIVAHPHSLALVAAAARAAETQLAAGPVVGTRTLWLPPAPRLLALGRDHAMVGPTRLNRRHSEMAVILALHPEGLTGDQLTSGLYDDDAAEATVRVEVNRLRHALGGLVRSRPYRLATDLPADFLDVARALREKDAAAALAAYAGSLLPRSEAPAVVAERHWIDVRLRSCVLESGDPGLLEDWIARFGAEDADARAALAGARRHATFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>W9DYX1</accession>
    <name>W9DYX1_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Assimilatory sulfite reductase (ferredoxin)</fullName>
            <ecNumber evidence="5">1.8.7.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">ActroDRAFT_0041</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">DSM 44927</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3 H2O + hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] = 7 H(+) + 6 reduced [2Fe-2S]-[ferredoxin] + sulfite</text>
            <dbReference type="Rhea" id="RHEA:23132"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.8.7.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism; nitrate reduction (assimilation).</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.7.1" evidence="5"/>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260325.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.44"/>
    <dbReference type="HOGENOM" id="CLU_003291_0_0_11"/>
    <dbReference type="OrthoDB" id="1128731at2"/>
    <dbReference type="UniPathway" id="UPA00653"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050311">
        <property type="term" value="F:sulfite reductase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012744">
        <property type="entry name" value="Nitri_red_NirB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017121">
        <property type="entry name" value="Nitrite_Rdtase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041575">
        <property type="entry name" value="Rubredoxin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18267">
        <property type="entry name" value="Rubredoxin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037149">
        <property type="entry name" value="NirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02374">
        <property type="entry name" value="nitri_red_nirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12" id="KW-0274">FAD</keyword>
    <keyword evidence="7 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 12" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0883">Thioether bond</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="16">
        <location>
            <begin position="2"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_C" evidence="17">
        <location>
            <begin position="321"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Fer2_BFD" evidence="15">
        <location>
            <begin position="423"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR_ferr" evidence="14">
        <location>
            <begin position="566"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="13">
        <location>
            <begin position="638"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR037149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF18267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ETA71023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="852" mass="89793" checksum="EE6DB58C68C9B239" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>W9DYZ3</accession>
    <name>W9DYZ3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secondary thiamine-phosphate synthase enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260331.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.49"/>
    <dbReference type="HOGENOM" id="CLU_096980_1_0_11"/>
    <dbReference type="OrthoDB" id="1691156at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="PTHR30615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004681">
        <property type="entry name" value="UCP004681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="SSF111038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="139" mass="15224" checksum="97D2677187C59224" modified="2014-05-14" version="1">MANFSTKVVPVRTGRTETVYDLTRTCEAFLDEVAERGDGLLNIFVPHATAGVAILETGAGSDDDLLAALRDLLPADDRWRHRHGSAGHGRDHVLPAFVAPHATLPVIEGRMELGTWQSVVLVDTNRDNPDRQVRLSFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ09</accession>
    <name>W9DZ09_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylamine N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260340.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.56"/>
    <dbReference type="HOGENOM" id="CLU_049918_1_0_11"/>
    <dbReference type="OrthoDB" id="1687886at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="PTHR11786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01543">
        <property type="entry name" value="ANATRNSFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="258" mass="29234" checksum="EA9A870838E0C5AB" modified="2014-05-14" version="1">MNEVSVTAHLERIGLPHPDRPDLDYLRRLHSRHLHAVPFENLSIHLGEDVPLNEDALFDKIVTRRRGGYCYELNGLLAALLRALGYQVSLLAVRVHGDNGFSPPFDHLALRVDLDEPWLVDVGFGRHSEFPLRLDYRDEQKDPGGVFRIEATPDGDLDVYRDGTPAYRIEQRPRELADFTIAHGFQRFSPTSHFTRSPFCTILTDDGMITLAGRKLITTTQDGVRTEETLEDDAQVLAAYRTHFGLTLARVPDHSQDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ14</accession>
    <name>W9DZ14_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Excinuclease ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">ActroDRAFT_0058</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.62"/>
    <dbReference type="HOGENOM" id="CLU_001370_0_2_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="508"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="556"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="535"/>
            <end position="542"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ETA71038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="852" mass="91608" checksum="CA7ADDE0DFC98D55" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ23</accession>
    <name>W9DZ23_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter membrane protein 1, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ActroDRAFT_0069</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 44927</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.73"/>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="103"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ETA71048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="333" mass="36608" checksum="1971530D62FB7239" modified="2014-05-14" version="1">MTDTATPRVAGDPIGSRSPLRRRAASPKGGAAPAAGERRRGRGPATSGWWAVFFLAPMGIGLGVFYIWPVFQTLYYSFTSWGPFGGHTFTGLANYRALLHDPALGSAFLNTLWYCLLGLLGIPVSLILAQVLGRRGRRGVSVYRTLMFLPVITMPAAVAIVWRWLYNGDYGLIDELLRKVGIKGPYWISDPHTVLIAVAIVGIWSTVGYNMVVLMAGIQGIPRTYYEAAELDGAGPVRQFFSVTLPLLTPSIFFVTVYSVIGSLQTFDLVYVLIGPQNPALPRAQSVIYLFYQDSFIDNNRGYGAAMAFALMLVIIAVTGLQFRLQKRWVHYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ34</accession>
    <name>W9DZ34_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131335_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="155" mass="16091" checksum="80D185DB04519B63" modified="2014-05-14" version="1">MLWGGVFMDPNLLEAVMGPIWAALGAIGHKALTDAEDDAAKGIVGLGHKLLARLRRRGGSTDPARAQLEAAAVDVANAPDDEDFRAALRGQVKKALAGTDSVDDPSLVEDLTKLLEAAGVQVSAEGAGSVAVHHNEGIISTGKHAKNSINRWGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ42</accession>
    <name>W9DZ42_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0089</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_999775_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="278" mass="29219" checksum="4CF5CEDDE0C34ABC" modified="2014-05-14" version="1">MRFNSPPGWPQPPEGWTPPPGWRPDPSWPEPPSGWRMWVGDDERPGTSFAPQRSTTMPWYGRTRYVTLLLIFVFPVGLVLLWLRGDWSVRRRGLISGATAVWALILLMTGTTSTPPTTVSLSPAAGQNSTSPIATAATTAVAPSQSPSALPSPSAVKPSPSKAAASTTQATHAATTHAATTKAPTTKTPTTHAATTQAAAEKSTCGAPKNPYGYSFCGTGGHLTSPASDVCSYFQCIASFWNGKGYMVECNDGDFSMSGGIRGACSDHQGVEQAVFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ47</accession>
    <name>W9DZ47_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding transcriptional activator of the SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.99"/>
    <dbReference type="HOGENOM" id="CLU_004665_2_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="1133" mass="121189" checksum="C6649A4606E8252E" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ58</accession>
    <name>W9DZ58_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450078.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_1_11"/>
    <dbReference type="OrthoDB" id="520970at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="448" mass="49387" checksum="7005EFC6AEA35DA1" modified="2014-05-14" version="1">MAKVPADIPAAPGALPLAGHLRQLLRDPLGFVSGLPAHGDLVRVRFGPMTIVVVCDLETTLRVLRDDRIFDKGGLLYDRSRVVLGNGLITCPHADHRRQRRVLQPAFSSERLSRYAPVMTAHAREAAEQWHDGQIIDVNKLMMQLTERIIAEVMFSDALAPAALSTALDDLGVVIPGIIRSMIMPPQLAWLPTPADRRFRRAHTRLRATLGEIIAERRADHADRGDLFSAMLSTAAASREDDDGPLTDTEAIDQAVSFFVAGTETTSSGLAWALYALGRHPEICERVRAEVDEVLGGRPGTYADVPRLELTGRVVTEALRAWPPAGWLLTRTVARDVRLGGHDLPAGTTLGYSPYVIHHRPDLYPAPDRFAPERWDAAHRPRREAFIAFGFGARRCIGDQFAFAEVVLALAVLVARWRFEPLPGPDVRPSVAAGLAPHRLRMRVADHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ61</accession>
    <name>W9DZ61_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_810465_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="342" mass="36007" checksum="E61EB163A8047B9C" modified="2014-05-14" version="1">MADAPLVESAALADTASENRSAGRGPAVWVAQSTAFGLLAGPLTSASVNHGHFVAGSLFADLLLIVWTVVFTFVAAGTQWHGAGAASVRVLAVLLLGSVFFMLPRADSLAATGSITSWDVLTRWLLCCIPYPLVALLIHPSTHRYVRVAPVAGLVCLALAWPQLLHHSIDTVAAQTRARFGIPGAMLLMVDPQSVSAFEGFGYSEGVLLSSYDSGGETPLPVPDYEADDLDMVVYKAEASTPCASIGKMIDSTVGDNGASDQSCLRLADGRWQYVGVPENTAVTQIELYDGYYVALTVDSASLTPIPASQLPALFATLHHPDNAELAALGESADQGLYGWLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ66</accession>
    <name>W9DZ66_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034272377.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.127"/>
    <dbReference type="HOGENOM" id="CLU_079354_0_0_11"/>
    <dbReference type="OrthoDB" id="931964at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="306" mass="33525" checksum="72BB0B720201C95F" modified="2014-05-14" version="1">MLEITVRAEIGWQRFVRPGIEELGALVSGLGERGNRFLTIQRIPDLPDHFIQTWHEAGGAYVVEYRDGGQDRQFESTLDGPEQVLAALTAWADGGSEWGSAWDWRPMDLEAAEPVAALDLAEKEHILLEQRVRLAIVAGYDGREQLNELAQEYLVTKERRPVSAAQAGQLVDRLWLERVAEQSAWVGETDPERLTRAFLALEGSGVTARENFTCCRSCGQAEIGAAGPSDARGFVYFHQQCTDAAAAGHGLMLLYGGFDGTAETTASIGRAVVTALDAVELPACWDGDPSRGVEVKPMDWRKRLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ70</accession>
    <name>W9DZ70_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolase or acyltransferase of alpha/beta superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_43_3_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="290" mass="31083" checksum="1B0FBDCB4ACEC2FE" modified="2014-05-14" version="1">MTVSAPTIGHAVSADGTRIGFEQFGSGPALVLVQGTMGTAYNFRELAEALADTYTVVVPDRRGRGLSPHAFSAAYTVDDDVRDLDAVLAATGARHVFGLSSGGDILLKAARSLPRIEKIALYEPAILPGGIPRKGAERFDAYSKADDLRGMLTTGMKLAEFGPALMRAMPDWVVKAAIGWIMKQEAKSGSDQYASMADLARAFRYDFVVVASMDGSIPTFKDITQPVLLLGGSKSPGYLGQALRALEKVLPGVRRVELAGLDHGAAWNIDRQRNKLGNPNAVAERLKEFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ74</accession>
    <name>W9DZ74_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260427.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.139"/>
    <dbReference type="HOGENOM" id="CLU_069356_28_0_11"/>
    <dbReference type="OrthoDB" id="1204683at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="201" mass="21748" checksum="DB79EEEEEFE8131B" modified="2014-05-14" version="1">MTSPERPARGRPRGFDREAALEAALAEFWRHGYEATSVAALTKAMGINPPSLYASFGDKRRLFTEAVERYAETHGDYGARALAQPTARGTVETMLRLAAERYADAGHPPGCLVIDGATNTTEASHEVKEQLRGYRERTKHAIAEKIEVDVRAGILPSGTDAAALAMFYAAVLQGMSTQARDGASRSDLERTVEVALTAWPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ84</accession>
    <name>W9DZ84_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260442.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166910_0_0_11"/>
    <dbReference type="OrthoDB" id="2004529at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="125" mass="13404" checksum="53DE7520A6F53358" modified="2014-05-14" version="1">MGDGTLQGWWGGGLFHVRGEGFEAGFALGSAEGVENVENVENVDVFVRRSDGSEWTATVFTLAEVHRLMDRWAESGEAQAGAYFWCSDGLIVRDAGVAAMVEVLAGLVASDDARTILRPVAEEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ87</accession>
    <name>W9DZ87_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260450.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_12_0_11"/>
    <dbReference type="OrthoDB" id="1864829at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="100" mass="10220" checksum="FB68C79D5A4B815E" modified="2014-05-14" version="1">MTTPLTLTSGRRPDGRDLLTAAGEIDMTNTAELAAALEALPGPVTLDLTAVEYLDSAGLGILFAHADRLELLAPDLLLPVLTHSGLAGIATVRPASASTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ91</accession>
    <name>W9DZ91_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sphingosine/diacylglycerol kinase-like enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450092.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045532_2_2_11"/>
    <dbReference type="OrthoDB" id="869726at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="50"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="306" mass="31747" checksum="5AF448167826A212" modified="2014-05-14" version="1">MSAIPAAQGSDTADVLVIHGAKADAAAVADLLSRYSDLCARGGRPKPRAVTTTPDDHGAGLAADAVRSGARLVVACGGDGTVNEVAFALAGTDATLGIVPLGTGNLLARNLGISADTDAALAVLVDGAERRIDAGRIDGRIFLGMAGMGLDAAMIEGAPETLKRRAGWAAYAVALVRHLSDRIQAVSVEVDGRRTRHRNVSMLLVGNIGRLQVGLEPLPDAEVDDGLLDLAVVLPRGPLAWLRVAAALRGGQAGTAERTIHRDRGVRITIRTRRPVPREFDGELLPAATSMDVEVLPGALRVRVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ93</accession>
    <name>W9DZ93_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260456.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.168"/>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_11"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="260" mass="27572" checksum="62B4295AC8838EED" modified="2014-05-14" version="1">MDLNLAGRRAVVTGASKGIGRAVSLALADEGVGLALCARDGGPLAEVAREVESRGVPVHAVQADVTNKSDIDRFIQDAATTLSGIDILVNNAGGAIPGDFFSLTDEEWQADIDIKLFSMIRCIRAAHPFLKQSDAGRIINIGAVFAHYPKPNFLAATTLRAAGHNLGKALAMQFAPDGILVNTVHIGYVETPQWQGIHQRRAPDKSWAEFHEQIAASEIPLHRFGKPEEVAGLVAFLASDRAAYITGVDIDVAGGMGIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ97</accession>
    <name>W9DZ97_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_820476_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="338" mass="34252" checksum="EEF47CEF589CBFB7" modified="2014-05-14" version="1">MTRTGKDAASRILGVAVALFPPDRRDWGQAMRAELAALEDPAARRRFALGCLRVALTRPSTLRTLGYPALMLGALAAAVWWSGRIGYGPLRWAVLAAAAALLAFVWWGRRPGALGPVGPGRVPRLARACGCMLVCALVLAGAASVASNSNPGEQAAVGVPIYTAVSAGYLFAFLAVTSRATAHRGAVPARTLAVGGGVGGAAAAIWVAVLATARPMPTATAPLIALIAGAVIVAAVVAPTSRRASGRPLTGRAKDGLIAGLCAGASAALLAVESLTALATYGPAAMIPDLAPVALTRADDLAQSRSEIQDPYVAILLLGGLLAIALCLSAIRVRRPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZA1</accession>
    <name>W9DZA1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator with CheY-like receiver domain and winged-helix DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ActroDRAFT_0169</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450096.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_8_11"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="130"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="130"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ETA71143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="248" mass="27300" checksum="3936E38FA56D67B0" modified="2014-05-14" version="1">MAYAELLVVEDDADIAAELLQALTGHGYHPVIAANGQQALAHVLDRRQPDLVLLDLGLPDMDGVALCRRLRALLPVESIIVVLTARTQEFEIVVALDAGADDYLTKPFRFTELLARLRAHLRRSRNTGGPAFIRLGRVTIDMRARRVFAGEREINLRPKEFDLFTALAGRAGAVVSRDELMALVWDAHWLGPTKTLDVHVSALRRKLEDADPGLGQAITTVRGRGYRCEQPTPPPAETSGGYSYSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZA5</accession>
    <name>W9DZA5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.182"/>
    <dbReference type="HOGENOM" id="CLU_092691_1_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="19"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="107"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="210" mass="21909" checksum="B4726CE1114BF012" modified="2014-05-14" version="1">MLRCDVVADGDGLLLPGPPTQVGLRFVPGPAAAEHLHRLHLHLTSASLAHQQDTVASALAIGARHVDVGQRPEEGHVVLVDPGGNYFCVIEPGNGYLAGTGFFGEVACVGTRDVGLFWSAALNWPLVWDRDQETAVQSPLGGTKVAWGGQPLAAKIARSAQRFLLTAPGGDLRAEIDRLVSLGAAIVSIGGDGSAELVDVDGNEFLLRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZA7</accession>
    <name>W9DZA7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260482.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144187_0_0_11"/>
    <dbReference type="OrthoDB" id="1377271at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="160" mass="18198" checksum="CA08F09712F8C14A" modified="2014-05-14" version="1">MIDRGRPVEAAEGYQVGDIVRLSAEPVEVVVSRVTVRTVFVEWPWRTVDPGHHWDGRMGFPRDPDHHDWRGTPWRMEPDGRGLSARDVCIVGVPETFARVELIEHFDPPAAFGWIPRPEWLLGLRPLEFAADLEAGFAFYLDDPEPVEIEVVTRISTSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZB4</accession>
    <name>W9DZB4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding domain-containing protein, AraC-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450100.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.198"/>
    <dbReference type="HOGENOM" id="CLU_000445_88_3_11"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="188"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="307" mass="34401" checksum="67B19D63EE774257" modified="2014-05-14" version="1">MDTSRDLFHFTDGAQAYAGRYLHLQDNPLHTHSFMEIAFTVGGQATHHCLAGRRTLETRDVVLLRPGVWHGYEDCRELELYNCCFSSELLRRELSWMRDDPLLGYLLWAGPYASHGRGTLAFRLEPDTFDLCVRQLESLSALRHLSPGEYRGDLIGRLTLLFGALARSVASAADTQSARLQPSHPAVGKVMRLFEADIARHWTLAELADQLHLAPGYLVRVFKAATGLPPIAYLAQLRVEHAAVLLLHTDEPVTSVGRAVGWPDQNYFARRFKAHYGLNATTYRQRFATHVDHHDGLPAAEPIPEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZD7</accession>
    <name>W9DZD7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphonate degradation operons associated HDIG domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260281.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.10"/>
    <dbReference type="HOGENOM" id="CLU_091985_0_1_11"/>
    <dbReference type="OrthoDB" id="1704279at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017670">
        <property type="entry name" value="Phosphonate_degrad_HDIG"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03276">
        <property type="entry name" value="Phn-HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA70990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="198" mass="20945" checksum="E4E01B8EA8F78B8E" modified="2014-05-14" version="1">MNAVTGQAESVVAELERFFTEQGAGEYLGEPVTQAAHMLQAAACAQAEGAGDALVAAALLHDVGHFTGTISGAQLMEGTDNRHSHAGADWLATWFPESVTEPVRLHVAAKRYLCAVEPSYFDRLSEASVYTLNVQGGPMSAEEAAAFEAGPYAEQAVALRRWDEAAKDPDADVPEFAHYRGLLAALVRRPGTGESVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZE2</accession>
    <name>W9DZE2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0013</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450057.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.16"/>
    <dbReference type="HOGENOM" id="CLU_069356_4_1_11"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA70995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="214" mass="23642" checksum="4C0A600BCA4E56C1" modified="2014-05-14" version="1">MGKGEQTRMAVLTQAAEVAARQGLGALTIGDLAARTHLSKSGLFAHFHSKEALQLDVLAYARDRFVDEVIRPATHTSRGLARVRALFEHWAEIGAHGKAECLFTSAAMEFDDQPGPVRDQLVRDHRDLMDSIAQMFRTGIAEGEFRADADPEQFAFELHGIMLAYFHAYRLLNDPRADERARRAFEAALADCLVAPQEQTQQTPDATPAAAQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZE7</accession>
    <name>W9DZE7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conserved protein of DIM6/NTAB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260295.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.21"/>
    <dbReference type="HOGENOM" id="CLU_075333_0_0_11"/>
    <dbReference type="OrthoDB" id="1681849at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="23"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="213" mass="23185" checksum="5FE16E116ADC445F" modified="2014-05-14" version="1">METSTTTFTRSEHVAISPKILYFGTPVVLLSTLNADGSANLAPMSSAWALGQSIVLGIGAPGQTALNLRERPEVVINIPSPELWPQVERLAPLTGRHPVPESKRGTFRYEPDKFGAAELRPEPSQLVSPPRVAECPLQFEARAEKLHEGGGGAFVIVEATVLRVHADPRLVVPGTDHVDPAAWSPLIYNFRHYFGLGPELGHTFRSETPRVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZJ6</accession>
    <name>W9DZJ6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nitrate/nitrite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ActroDRAFT_0043</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 44927</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450065.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.46"/>
    <dbReference type="HOGENOM" id="CLU_033198_0_1_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17341">
        <property type="entry name" value="MFS_NRT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="PTHR23515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ETA71025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="441" mass="46247" checksum="993C39294F6152D2" modified="2014-05-14" version="1">MATFRSSSRAPLTGWRPEDPRFWYDGGARVARRNLFLSILTEHVGFSVWSLWSVLVLFLGPADHVDAAGKFLLTAVPTLVGSCLRVPYSILVVRFGGRTWTVISALLLLIPCGAAAIAVKPGVSYGTLVLLAALAGVGGGNFASSMTNINAFYPQHRKGWALGLNAGGGNLGVAVVQLVGLAVLSWAGAGHPRLLAGIYLPLIVIGAAGAALWMDNLPRPETRYRAVREVCKEPHTWIVSLLYIGTFGSFIGFSFAFGQVLQIQFAGQFATPVKAAGLTFLGPLIGSLARPLGGRAADRWGGARVTVWSFGAMAVGAAAVWESSRTHSLPGFVAGFVWLFALSGVGNGSVYKLIPGIFKGRTGDPARDQALGGALIAIAGAVGAFGGVLVNLAFRESFLTYHSATGAYVAFIACYLVCGVLTRLVYQRAEVPAAKPVPASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZL0</accession>
    <name>W9DZL0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ActroDRAFT_0049</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 44927</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.52"/>
    <dbReference type="HOGENOM" id="CLU_036805_2_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01007">
        <property type="entry name" value="TRANSPOSASE_MUTATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ETA71030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="442" mass="48589" checksum="E6BC10B6C4E14F43" modified="2014-05-14" version="1">MDQVLSVEAEEHLVEELEQVEGARRVAAILAPEAIDSLLAEAEKAGGGAQELLAAITKAVLERALQVEMADHLGYEKGDPAGVGSPNSRNGSYPKTVVTASGPVRLQVPRDRAGSFEPRIVPKRTKRLGQVDEMILSLYARGMSTRDIRDHLAEVYGAEISPALVSNVTEVVREEIAEWQNRALDAVYPILYIDAIVVKVRESGSVVNKAAHLVIGVDTDGYKQVLGIWIEQKEGSRFWLNVLTSLRNRGLKDALVVCCDGLSGLPEAIGHVWPEAIVQTCVVHLIRTSMRYVAYADRKKIAAALRPIYTAANASAAEAALEALRGTFARSAPGVISAWERSWETFIPFLDFPLELRRVIYTTNAIESMNFQLRKISKTRGHFPDDDAAIKLLYLGIRRIEGRHIDGEGRHVPAGQLRGTGTYGWKRALNDFAIRFPGKLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZL8</accession>
    <name>W9DZL8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2821448_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="66" mass="6967" checksum="CB114E5F97EACA36" modified="2014-05-14" version="1">MPGAGPGWSHGSMTHNSRDTKPGDRTFDMISMLGVVCVVLCVIAGLVAVGWFILLGLAMSRYGSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZM3</accession>
    <name>W9DZM3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260346.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.64"/>
    <dbReference type="HOGENOM" id="CLU_061724_0_0_11"/>
    <dbReference type="OrthoDB" id="1438002at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="274" mass="29137" checksum="8DA25EBFE69CEE8B" modified="2014-05-14" version="1">MPHPQAKIHRMAELIEPIGAVTFSDVPNEAFLALGMRNYWDGYFAGRAAPLGQAPAEVVHAVFYNFAAGEVARHIPWVWGKTTPEEAIAVRERGSAAALRQMIGALADSPGLVRAADLACRAALSAPTEGRALYAGLRALDVPEEPVARLWHVATLLREHRGDGHNAVLLAHGIGGTEAHVLLALSLGMRAEEFGRVHHLPRPQLAAVVDGLRERGLVNAAGGFTDTGRATRERIEALTDESAAPAYDVLSAEELDELIAGLEPIAAAVQAAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZN1</accession>
    <name>W9DZN1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator/sugar kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.75"/>
    <dbReference type="HOGENOM" id="CLU_036604_13_3_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="396" mass="40937" checksum="A0F5B6D3FAD2DF8B" modified="2014-05-14" version="1">MGDPGAAGQEPVLLRRVRLLAVIDALREAGPTPLTVLATKTGLSRPIVQSLADELVEMGWVEARTPEELGDGGRSVGRPARRFRFHAEAGLIAGLDIGAHTVTGLVTDLDGTVLGRSRLTVSPAAPPAERLERAHAALQDACAEAGTTPAKLWHLGVASTGVIDHAGRVMLSVALPGWTGVDIAGAFAEKVGCPVVVENDGRAAALAEQWRGVGRGVEDMVYVHAGLRTGTGIIVGGKMLRGHSGAAGEIGALPSAGWAEAPMHLLGFPGLAPDAPQEQLPQHVFARAREGDEAALAATQRYVRALSSGIAALVLTFDPELVVLGGGISRSADLVLGQLVSELERVCVRLPRVVASPLDAEWVALGAVRVALDAVQQRYFDPAASEALAAPGQLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZP0</accession>
    <name>W9DZP0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260378.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2662845_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="75" mass="7986" checksum="7E271CEACADC11A2" modified="2014-05-14" version="1">MTGFATRSTLPGVVGDDTAVTILPAAEFAEQLAAAQAMLAWAEKHPNAACEYREVWAKHVRGMQAASARRTARAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZP5</accession>
    <name>W9DZP5_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1990 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450070.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080841_0_1_11"/>
    <dbReference type="OrthoDB" id="1586328at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018960">
        <property type="entry name" value="DUF1990"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014457">
        <property type="entry name" value="UCP010260"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09348">
        <property type="entry name" value="DUF1990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010260">
        <property type="entry name" value="UCP010260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1990" evidence="1">
        <location>
            <begin position="5"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="187" mass="20397" checksum="F4A694308BD33D75" modified="2014-05-14" version="1">MAEFSYPEVGATRDGGPLPAGYKHVKYRAQVGRGRDAFEQASSMVLEWRMHAALHLRPRPERPRAEPGSRVQLALGPIRAQCAVVWALDEPRRRGFAYGTLPGHPECGEEAFLIEWDDHDDVWLTITVFSTGAAWYTRAIGPLVPWFQRLYAVCCAAVVRRAANSAGSAGGAGEHCATGARAEHDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZQ0</accession>
    <name>W9DZQ0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal peptidase I</fullName>
            <ecNumber evidence="3">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ActroDRAFT_0092</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 44927</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3"/>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028723_10_0_11"/>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S26" evidence="5">
        <location>
            <begin position="12"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ETA71070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="180" mass="18468" checksum="53DF16F679A33671" modified="2014-05-14" version="1">MLQAALVGAGIVVLALAAVAATVRRRLTVVLVDGESMSPALSSGDQVLVARSSRSTRISVGDVVVFRYASGPEEKLIKRVAAVPGDLVPRNVLGAVDAQPGTRVPQGFLVVIGDGVQSTDSRDFGYLAADQVTGVVLRRLSGSGRRVSIPARADARADTRPAARPAHGVAPSGSRPDAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZQ5</accession>
    <name>W9DZQ5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260392.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2949851_0_0_11"/>
    <dbReference type="OrthoDB" id="2104639at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004921645" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="59" mass="6369" checksum="9A443FF165AFB99E" modified="2014-05-14" version="1">MLNLLERMGDRMLGRFVPRVPAHATQCSAGGSCGTNRVWCYCEYPPGSKYCAAAGAKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZT3</accession>
    <name>W9DZT3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, ribosomal protein N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.133"/>
    <dbReference type="HOGENOM" id="CLU_013985_3_4_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="183" mass="19820" checksum="B7FF73C69E51AF37" modified="2014-05-14" version="1">MTSPMTLTVGPSATAPALTLRPWQDSDIPAVVAAHRDESMRRWLTRSIGNEDQARAWLAEVDAGWAADTLLSWAIEEEGALVGYFVIKAANPPKTLATGVGYWTVAEARGKGIASRCVEAATEWLFSGQEIMPADEIELLHTVGNAGSCRVAQKCGYVLDSVLAPLPPEFPDQGHRHLRKRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZU2</accession>
    <name>W9DZU2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type transport system, involved in lipoprotein release, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0139</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009266_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919352" evidence="2">
        <location>
            <begin position="38"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="908"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="964"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1009"/>
            <end position="1031"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="1047" mass="104477" checksum="8DE9120B8A748146" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZV0</accession>
    <name>W9DZV0_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0151</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_7_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="19"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="120" mass="12676" checksum="18F510D17DF1CCAE" modified="2014-05-14" version="1">MIFRVLSGTSPARPGEVPVVQVTGELDFHNAARLREALVAIHVDSGKGLVLDLSELTYCDSTGITVLIGVHQRAEAAGGRLVLAAMNTELSRTFAMIGLDQIFSTEPSVEGAVERLESAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZV3</accession>
    <name>W9DZV3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034272405.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.164"/>
    <dbReference type="HOGENOM" id="CLU_027402_33_6_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="116" mass="13010" checksum="F7CCF07C89EBFD70" modified="2014-05-14" version="1">MAGQRKYPPELRERAVAMYRAAEEKPVVRAMARQLGVHPEALREWIRKDEEARCSGPGRGGARRGALVDVPELPAQVEAELAGLRKEVMELRRANEILRAASAYFAVQLDQTGRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZV8</accession>
    <name>W9DZV8_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0161</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115403_3_2_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="18"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="118" mass="12395" checksum="ABB4F71C9137E4F7" modified="2014-05-14" version="1">MMEQGPEALEVTVLDAGDGKALIKIVGELDLARAEPLREVLTSAVAAHAVTVLEMSRCPFMDSTGLRALLAGAHRAGETGHALRLAAVRPEVARVIELTGTHTLLPAYPDTTAALETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZX4</accession>
    <name>W9DZX4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ActroDRAFT_0182</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.190"/>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ETA71155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="345" mass="36551" checksum="26AD8148C6FAE007" modified="2014-05-14" version="1">MDSAKQTKRVTIKEVAQHAGVSMAAVSKVLRNAYGTSPAMTEKVKASMAALGYRPSSAARGMRGRTYTIGVLLDNLRNSFFADILDGVHEELLDTDYTVLIGAAGFDAAGQAHTIEAMVDRRMDGLILIAPGTSRSEVLGFAAVTPTVVIGHHDAAEVHDSVLDADDMGAAMVVDHLVSLGHRRIALFSSPGTKSSQWRKTPEIVLTNGYLEAMQRHGLEDLATVVRAPYSDDGGYKAGLDLLSASHRPTAIMTGADIAAMGVFRAADELGLRVPEDLSLAGYNNTALAALTSVQLTSVDQAGRTMGSAAARMLIERVEGRRTRAMQTTMTPSLVVRRSTAAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZY0</accession>
    <name>W9DZY0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ActroDRAFT_0187</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_5_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="40"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ETA71160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="255" mass="27718" checksum="FEE433877C706CE0" modified="2014-05-14" version="1">MCESRISCGSRYQAFDVEERSAVTGTEEAGTTAGAARDRLVAAHLHLVEQEAAQYRTWRLDRADLHQAGAVGLLIAASRFDPQRAVPFGAYARIWVRKEIQRAIARQEFPMVLPPDLVGRTVVLRRALDENADRLTLAAAALGVSPGTAAALHRQLSAVSIDADEDLFAPGFAMPFADGGPTPETAVVAADFADVIRLALTRMDARRAAALVLRYGLDGGPERSFREIGRQLEVSGHTARTYVEQAQTQLRRLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZY5</accession>
    <name>W9DZY5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260498.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2821449_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="66" mass="7588" checksum="C9258CEFAEC44D9B" modified="2014-05-14" version="1">MTDSKTELQALMAEYERATSTRDINQVIPLICAGATYRFTWTGRVDGRRRSEYGRGTNMIAKQRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZZ0</accession>
    <name>W9DZZ0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260505.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_33_0_11"/>
    <dbReference type="OrthoDB" id="1839196at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="96" mass="10798" checksum="EFD88077E7796194" modified="2014-05-14" version="1">MGAARKKYTAEYKAEAVDLVVNSGRPVAEIARDLGIHEATLGNWVNLAKKNGTVAEKPVTADERARLRELEDENRKLRMERDFLKKAAAWFASQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZZ4</accession>
    <name>W9DZZ4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260509.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.215"/>
    <dbReference type="HOGENOM" id="CLU_109394_0_0_11"/>
    <dbReference type="OrthoDB" id="1336167at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="182" mass="20464" checksum="D021C2191CA2D806" modified="2014-05-14" version="1">MRPEPGQVLHFSEDPMIARFAPHVAATAQQAESYVWAVDWHNAPSYWFPRQCPRAMAWATARSSDEDRTLILGPGGGERVHAVEYGWLEAMRTVKLYAYRFDAARFRPFGTPAEPHAWVSEQSVLPLGPAEPVGDLFALLEEADIQLRVLPNLWPFWNAVVSSTLGVSGIRLRNAKPQDQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4F5</accession>
    <name>W9E4F5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260338.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.55"/>
    <dbReference type="HOGENOM" id="CLU_083287_18_7_11"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="143" mass="15865" checksum="66DC443DC1425AF6" modified="2014-05-14" version="1">MPGFLDLHGRTNKAVRAAADARIRRHGLHLGQDHLLALLWAQDGRTPGELAAALEVSTPTVVKAATRMSAAGLLERRPDERDHRLVRIWLTDAGRALQLPIEQERRRLEEELIADLSPAERDQLLAALAKVHQAASRLQQDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4G5</accession>
    <name>W9E4G5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter membrane protein 2, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ActroDRAFT_0068</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 44927</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.72"/>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="94"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ETA71047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="298" mass="32513" checksum="CC096EC16CE8180A" modified="2014-05-14" version="1">MADSTLPQRPPGAARALDEPSRQRPNRRVLGSIGAHGFLILASVLLAGPFLWELLTSFKSLTESVAVPPTLLPSSWHLSNYTNVLDAVPFGSELVNSVINALARTAAQLLFCSMAAFAFAWLKFRGRGVVFALFLSVLLVPTQLLVIPQYQIMQDLHLLNTIPALFLPGMFSAFGTFLLRQFFLSLPPELHEAARLDGAGPVRIFWSIMLPLARPGLLALGLLTMIWSWNDLLWPLIVNDDPGKMTLSVGLANLQGVYLTNYPVLMAGALMATLPLIIVFVVMQRRVVEGIALTGTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4G7</accession>
    <name>W9E4G7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-mannose binding lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260365.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.77"/>
    <dbReference type="HOGENOM" id="CLU_019346_1_0_11"/>
    <dbReference type="OrthoDB" id="323324at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00028">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="SMART" id="SM00108">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="SSF51110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004923237" evidence="1">
        <location>
            <begin position="37"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Bulb-type lectin" evidence="2">
        <location>
            <begin position="428"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="539" mass="56872" checksum="E352571783D4BC0A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4H0</accession>
    <name>W9E4H0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260373.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_11_3_11"/>
    <dbReference type="OrthoDB" id="1975314at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="176" mass="19295" checksum="633A36D57F7590E5" modified="2014-05-14" version="1">MFDATLGEVATIRDYRPGDAPALWTLSTLPNVGHTADATVPIELPAARAAPSQFADLADIPAHFIGPGGVFLVAEHHGHPVGMGGFRPNSRGQAEVLRVRIHPALRRTGVGRALMEGLESRAADHGFREMSLDTATNMPEAMAFYRALGYRETARETRPEWTWTLVYYTKQLFPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4H6</accession>
    <name>W9E4H6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arabinose efflux permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ActroDRAFT_0088</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">DSM 44927</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.91"/>
    <dbReference type="HOGENOM" id="CLU_000960_28_2_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="31"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ETA71067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="512" mass="51680" checksum="A3BA0AD32429C907" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4H8</accession>
    <name>W9E4H8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC-type multidrug transport system, ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ActroDRAFT_0094</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.98"/>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004923240" evidence="9">
        <location>
            <begin position="29"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="40"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="352"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="496"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="496"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="386"/>
            <end position="393"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ETA71072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="648" mass="68427" checksum="7742360E51904605" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4I1</accession>
    <name>W9E4I1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC-type multidrug transport system, ATPase and permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ActroDRAFT_0099</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.103"/>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="51"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="364"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="398"/>
            <end position="405"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ETA71077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="637" mass="67576" checksum="D3B1679CA7F02117" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4J0</accession>
    <name>W9E4J0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">D-alanyl-D-alanine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ActroDRAFT_0114</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450080.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.120"/>
    <dbReference type="HOGENOM" id="CLU_606406_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S11" evidence="10">
        <location>
            <begin position="147"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="6">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ETA71092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="451" mass="44865" checksum="48F36A39878F41F9" modified="2014-05-14" version="1">MSSERRLPRSRRRATVVSTAVGAAVVIGCTVLLIPRGSTQTAADLPANSAIGDGSGAPGASATGTASAGASASASSSASASASASASASASGSATPTSTAAFSGPPKLSIGSSQNVAGTLQPTWPNQGQAEIDLDGSVIKSYGPVSSSQPIASVTKTMTAYLILHDHPLSPGQQGPTITLTAADVTAYKYDVSENMSSVPVKAGEQLTESEALQALMLASADNIADVLAHWDTGTTTDAAFVSKMNSEASALGMSHTHYADASGYDPDSVSTAPDQITLAQHAMGLGYFAQLVDEGSAKIPVAGTISNYNSLLGYDGVNGIKTGSTGQAGGCLLFHADFTVNGRTLTLSGAVLGQDAPTGQELGVGLAAAKTAISSTESQVTARTLIPAGTAVATAPLADGTTATLHTTANLTVTAWPGETVTLRLNTSGTTHTLKAYASDGTLLGSTTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4J5</accession>
    <name>W9E4J5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase, aryl-alcohol dehydrogenase like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260425.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.136"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_3_11"/>
    <dbReference type="OrthoDB" id="1054546at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="11"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="317" mass="34478" checksum="5688D99A0EAE2149" modified="2014-05-14" version="1">MTDKALTVPAVALGTWAWGDSGEAGDGIFGSRLSEPGLREVVEKAQSNGFTLWDTAAVYGMGRSETVLAKALKGYDRGEYQLSTKFTPQAAGDSDDPVGDMLEQSLERMGTDHVDLYWIHNPRGVARWTPLLIPLLRSGKVKHVGVSNHDMQQIALADQILGEAGFRVEAVQNHFSLLYRASERAGILEYCREHDVRFFSYMVLEQGALTGRYGPANPLPEGSNRAEVYNGMLPRLQALTDRMGAIGEDRGAPAADVATAWAIAKGTTPIIGVTKAAYIDGLVRARGIELAEEEITELEALADAANVDTRGWWEPDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4K0</accession>
    <name>W9E4K0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Stage II sporulation protein E (SpoIIE)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.155"/>
    <dbReference type="HOGENOM" id="CLU_1105306_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="29"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="251" mass="26621" checksum="7577B90019D72E11" modified="2014-05-14" version="1">MAATAGWPGEPGGTGDLSEGGSQRGEPILPAGLLAAAEAAAPQLSVTDAMGLDVNAALLATVAVGALRRARRAGADLAEQAHEADRALREHGHQGYATGQLLRLNLRDGTSEFVNAGHPWPLQMRDGKVWEIVPEVHMPFGFSHYFHTQSKTGYRVQSLDLRPGDRLVIVTDGMLERNAAGLDLVDLVARTRQLHPREASRALVGAVVDASDGHLCDDATVMCLDWHGSAHSYRDAATGADLSSASHRNTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4K3</accession>
    <name>W9E4K3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1033026_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="269" mass="29667" checksum="DE7642A2FACB6B5D" modified="2014-05-14" version="1">MRGCALFSVGPRRQSGTCREVKRRRFPLVADSAGRRLTSRQNPDRASPARPRREPTPWGIGASCARAESHPAARPQGEHPRCGRILHRRFGSLVPSLLLQRRKARSSARKSPVFLLIRRKLDSRLLSVAASSMEEYGGSDLRREGWWTGWLRGRRQGCGRKQCRISPRGVRPGHAILRSARAPGGSDRGDAESFRIGRGPARGVLPRGLGSGRTHQRGAGFHFRCDRSTDAFARIEDRDRRIRVMQNPSAPGAAGPRAGLQPSAARTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4K5</accession>
    <name>W9E4K5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative naringenin-chalcone synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ActroDRAFT_0163</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450094.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.172"/>
    <dbReference type="HOGENOM" id="CLU_034992_0_0_11"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012328">
        <property type="entry name" value="Chalcone/stilbene_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001099">
        <property type="entry name" value="Chalcone/stilbene_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011141">
        <property type="entry name" value="Polyketide_synthase_type-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11877">
        <property type="entry name" value="PTHR11877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02797">
        <property type="entry name" value="Chal_sti_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00195">
        <property type="entry name" value="Chal_sti_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000451">
        <property type="entry name" value="PKS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chal_sti_synt_N" evidence="3">
        <location>
            <begin position="81"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Chal_sti_synt_C" evidence="4">
        <location>
            <begin position="275"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000451-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ETA71137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="358" mass="37468" checksum="AAC846862719E3C0" modified="2014-05-14" version="1">MSKSQSAPVCVHRPVFVEAEHRVGIDEVVERSGLAYPGRAVPDKFADIMRNTGVDTRTFIRSAKEVYTDGTAPAHWASTVALLAGLGARAADAALRASGIEPQEIDALIVTSVTGYAMPGMDVDLIRELRLRPDVRRIPVAQIGCAGGLYGLIRASEQIAARPGSKVLVVASEAFSSTTQPHTRRADALIYKALGGDGAAAAVVTPADQAPDGPHVLLDGVGALDYLIPDTTAYYRLTADDEGRLGFASTPAAPGAIHLARPALESWLGESSPGFLVAHHGGPAILENTAEVFGADQRQLRHSWASLQNHGNMGSVSFLDILQRTLGETGPDAMYGPGTAVTIGPGVTVCAARLTRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4K8</accession>
    <name>W9E4K8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074761_0_1_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011152">
        <property type="entry name" value="Pesterase_MJ0912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000883">
        <property type="entry name" value="Pesterase_MJ0912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="5"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="262" mass="28093" checksum="FD019AA20819E495" modified="2014-05-14" version="1">MLVPMRLGVIADIHGNDVALRAVLKDAESLEVDRWWALGDLVLFGPRPVEVLQLLRTLPGIEMLRGNTDRYVLTGEQPAPHATAADAVASLDLVQRYAAMAAGIGWTRGVLDQAGVLTALTTLPTRLRLQLPSGTSVLGVHASPAADDGSGISPEITDERLRLLLAGCDADIVIGGHTHRMTDRHLDGIRVLNPGSAGLPHGADTTSWLLLADEGHGPTVTHRTVPFDVNAVVEDLNRRRHPNTDFVTSILTGRRPLRSSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4L2</accession>
    <name>W9E4L2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carbohydrate ABC transporter membrane protein 1, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ActroDRAFT_0184</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 44927</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260489.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.192"/>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_11"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="68"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ETA71157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="294" mass="32353" checksum="6783FB828B9F5CCF" modified="2014-05-14" version="1">MHRVLGDKRAIAILLGPALLVYSLIMLVPMFWSVGYSFTKGNTIEGFTWTGFTNFSHLWSDPNAHQALWFTLKYAVVVTVGQVAVGYLLALLYVFFLKRASALVRTLVFFPMVLPTVAVGLLFKALFQIAPQYGPVNQLLVDVGLHPIDWFSSTGTAFIVLVVMDIWRSMGFYAVLLYAGLVDVPDDILESARLDGASGLRLVRHIVLPLSFPVLMSSLIFSINGTLKVFDSILPLTNGGPGNSTTPLTVLMFNTAFDYGNYGYGSAIAFLLTVVCLLVTLLVFRLSRRDLQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4L5</accession>
    <name>W9E4L5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-glucosidase-like glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0189</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.197"/>
    <dbReference type="HOGENOM" id="CLU_004542_4_2_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004921794" evidence="2">
        <location>
            <begin position="23"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="Fn3_like" evidence="3">
        <location>
            <begin position="648"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="733" mass="76476" checksum="F3DF761A2D162A0A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4L8</accession>
    <name>W9E4L8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1194340_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919461" evidence="2">
        <location>
            <begin position="34"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="221" mass="21871" checksum="2ADAA3342E73DE70" modified="2014-05-14" version="1">MRRLAGIAAGVVCGSAFVLTGCSSGNGSSSPQATSPQAPGTGAAGAPPGAQVLGTVDVGQPFTITFPSSNTAQPSKLKLTVKSVVCGKGLDPAVIAYAEQGGTSSAPPTPAGGSQFCVVSMTAQNVGDASATWSANYGVGLNVGAVQYVETSNDQDLELDYAQVWFQRGQPSPTFGINPGAAGPVNGVFEIPVGAKPTSAWVSGGSITALNGPAPGYLVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4M1</accession>
    <name>W9E4M1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RHS repeat-associated core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.211"/>
    <dbReference type="HOGENOM" id="CLU_000662_1_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1659"/>
            <end position="1684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="2170" mass="227996" checksum="2E5D9460532B09F8" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4V7</accession>
    <name>W9E4V7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphatase, C-terminal domain of histone macro H2A1 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.6"/>
    <dbReference type="HOGENOM" id="CLU_054419_1_2_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="4"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA70986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="174" mass="18826" checksum="EC087E088A595E33" modified="2014-05-14" version="1">MSVVAASVISMNELTGITYLKGDATSPHGKGRKLIAHVCNDAGGWGKGFVLAVSKRWPKPEQEYRRWHRDRASSGFALGAVQVVQVEQYVWVANMVGQHGIRTGSNGPPVRYDAIDTALAQLAAEARDLAVSVHMPRIGCGLAGGNWERVEPLITARLTTARIPVSVYDYEEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4V9</accession>
    <name>W9E4V9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260285.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1583079_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA70991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="168" mass="16884" checksum="51074684F4975259" modified="2014-05-14" version="1">MSESTTPAAAPAVARPSAAGADDEHAVAVVRMRRSSLGALFLLVIQAILGMCAALYGPLPHADKGKGLLASFGDSVTKGPASVAMHAGFGMLLFIGACLVVVFGLTVRYTAVRIASVLGWLCIAGAAVAGAASVNAGGAKADSLTMAVLTFVAMACYGVNLYVLGEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4W8</accession>
    <name>W9E4W8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Threonine dehydratase</fullName>
            <ecNumber evidence="4">4.3.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0029</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="4"/>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450060.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.32"/>
    <dbReference type="HOGENOM" id="CLU_021152_4_2_11"/>
    <dbReference type="OrthoDB" id="1876944at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:L-threonine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="37"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="326" mass="32625" checksum="4427871030836E3B" modified="2014-05-14" version="1">MADRSTAPSLIGPADVAAAADRVSGRIRPVTLAPADPGSSGTEGAHVTFALEYLQHTGSFKARGAANLAAAHQQAGTLPEVGVAIASGGNAGLACAWAARATGTRATVFVPLSAPAVKVEKLRGYGADVHQVGSEYADALAASRTFAAASGALLSHAYDNPLIAAGAGTLAAEILAASPRKVDTIVVAVGGGGLFAGVAAAVSGTGIRTVAVEPENCRALNAALAAAGPVDVAVESVAADALGARRTSQMAYELARGEHVSSVLVPDAAIVEARRHLWETYRITVEPGGATAWAALRSGSYKPEEGEHVVAVLCGANTDPADLVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4X3</accession>
    <name>W9E4X3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative anaerobic dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0039</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051452245.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.42"/>
    <dbReference type="HOGENOM" id="CLU_000422_13_4_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin" evidence="2">
        <location>
            <begin position="43"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="3">
        <location>
            <begin position="562"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="683" mass="72161" checksum="CB0439AD95121FF4" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4Y5</accession>
    <name>W9E4Y5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ActroDRAFT_0056</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260344.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.59"/>
    <dbReference type="HOGENOM" id="CLU_000445_90_10_11"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="17"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="160"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ETA71036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="232" mass="24921" checksum="735592A356B9B98F" modified="2014-05-14" version="1">MTDEDGVGAEDRDAPLRVLIVDDHPIWRDAVARDLAAAGFDVRASVGEGRQAVRIVPGLGCDVAVLDLHLPDLSGPELIRGLLQRCPALRILVLSASGEHQDVLDAVKAGASGYVLKSASSGELVDAARRTAAGDAVFTPGLAGLVLGEYRRLADRATGPETDTPRLTEREMQVLRLVATGLTYRQIAERLTLSHRTVQNHVQNTLTKLQLHNRVELVRYALDNGLGDDAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4Y7</accession>
    <name>W9E4Y7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolase or acyltransferase of alpha/beta superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260348.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.65"/>
    <dbReference type="HOGENOM" id="CLU_020336_43_0_11"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="26"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="268" mass="27863" checksum="AE72F3C4B5A97298" modified="2014-05-14" version="1">MTELRATSADGHPVTALVDGSGPTTLLVVHPGGSDASTWDDVTRHLAAEFRVVRIRRRIYAGGAEIALPHSMAVEAADILAVARLLTAPVVLVGHSSGAVAALEAALLEPSACNGLFLYEPPMPTTELLCGPAAAHARAALDAGDPVEAMRIHMRDIVRMPAAIVDAMFADPGAQGLFAAYAAAQIADDEAIDALGAGIDRFTTLDLPTTFLEGDLSPAHLRERVADLAATLPNAKVVTLTGQGHIAHLTASESLANVIRDAVSRPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4Z4</accession>
    <name>W9E4Z4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_555087_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="491" mass="52441" checksum="903ACD8A4FD1034C" modified="2014-05-14" version="1">MSSQGFFESEPRYARRLVQEAGEDAARSDERIRRSVLDADQRIDDLTRQVEFLTRAFEAFVELGDVRTELARFLPAAAARAAARTFIKSLVPSQDSVLLRDSGDVPGYWLPLAASGLALLLRADPGAEPQVAAACERDAERTALFLALGLRLGGAAQLAGPYLAAALPPPSADGVVTVAARHLWCALADGHYGPAARTALASWLEALVASISAADLRAAVEARRGQSPVEFGPFPRPTFGPRVPRSAAIEAALKSAAAAATSLVRLERWYGAEPDDPNAPAAAADVAACEPVINMLIDEGSPEEGPLLRRAAELEILTRTKIAPPAAPRWDDPAGYGPEVVVADLLAADPELAARRDLARAALCRPVAELAESLLADACPQPPAEMTVSLEDDTLTLAYDRSPDAEIDRICAEIERRAAEAGARGNRKYAADQLRRAVDRKAEHSTLIRSAGERLLDYRAQAAEIRAAAEASHQSLMHRMGQVAEWANPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9E515</accession>
    <name>W9E515_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.148"/>
    <dbReference type="HOGENOM" id="CLU_137765_0_0_11"/>
    <dbReference type="OrthoDB" id="1226903at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020323">
        <property type="entry name" value="DUF2716"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10898">
        <property type="entry name" value="DUF2716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="178" mass="20968" checksum="67021473BA594437" modified="2014-05-14" version="1">MNTWDTWVASHRFDSAAWAQVRADEEHELWDRFDAAFCFRPSMHELPGINEPTPSITYDLVYEDATRVEPVWVNRTLLTALRRVTGIDDSVVVLNWHHQTYRCRPHRVRDEEPVDDTWPTEIYPDYDYYIWLAEDMRYGTFGHPWEPSLCIFGEELIAAVTEVGDEALGRILRRNGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>W9E518</accession>
    <name>W9E518_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ActroDRAFT_0152</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 44927</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_063627905.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.159"/>
    <dbReference type="HOGENOM" id="CLU_031275_3_2_11"/>
    <dbReference type="OrthoDB" id="944044at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ETA71126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="394" mass="41867" checksum="59DB92CD830EB375" modified="2014-05-14" version="1">MPDRPVPTTADRGVGGRLDRASGYAWRLLVLGVATYVVFRVLLRFEAVVVAVFMALIVASLLRPPVNLLSRFLPRRLAATVTAFGVLGLIALIVWQMTESVTNEWSALSAEFSGGIRHIEQWLEKRPFHIKPDTLTNLQGKAGSYIEAHRSALVSQVLNNAGRVVDVVTVLALALFCSIFFTSSGERMWLWFQDQLPATARPTWRRAGSVAWHTFAGYTRGIVLIAAVNAIMVGIALEILRVPLALPLTLLEFTASFIPLIGSPIAMAVATVVALAGRGVTTAAIVLVLIVVFGQIEGHVLQPFVMGWSVRLHPVVIALSVIAGTICAGLLGAVAAVPLVSIAWAVIKELRGNGEPDPDEDDGADADDGHTSAVEADSAATGRSALPVGPGPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>W9E520</accession>
    <name>W9E520_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.165"/>
    <dbReference type="HOGENOM" id="CLU_027402_4_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13333">
        <property type="entry name" value="rve_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="122"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="357" mass="39757" checksum="611CA7C47E2C2282" modified="2014-05-14" version="1">MRFLEENQAAFGVEPVLRELAIAPSTFGDWRRRAVAPCARQVRDAELLARIREVHADSGGVYGSPRVHAVLRREGEAVSRKRVERLMRENGIVGVSPARKVRTTIPDPDDPRPADAVNRRFTAVGPNRLWVTDLTVIATGEGPLWLASIRDAFSRKVIAWESSDVADADLVCAVLEYALRSRRPPADGSLVHHADHGSQYTSIKLSTRLVRAGITASMGTVGDSYDNALAENMWSTLKTECVRRREFATRAEANQALFEYLDGFYNPRRIQRNLGYRSPDEYEAAHDAGELTAADLERLARDATRRRHRRTERAKSPALPAGPQARQLPGQRPTPTAKRVPPSGRTRPQQENTRSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>W9E522</accession>
    <name>W9E522_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1944106_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="129" mass="14304" checksum="32DB69DF2FDC1697" modified="2014-05-14" version="1">MAGAFAASSEAHWRATGAYIDGECSREQLLEAVAAIRKIETRGERWGMVETPTLVSGVLALCLRFEETSVQRWHKTLRDLANDAQSVVAEKASQRALDDPKKAYAAARWEEARWQLQYIIATEPNLAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>W9E523</accession>
    <name>W9E523_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase, aryl-alcohol dehydrogenase like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260464.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.176"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="OrthoDB" id="1367386at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="14"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="286" mass="30158" checksum="7F2606437694FE78" modified="2014-05-14" version="1">MQTRRIGDRAVSAIGLGGMPMSIEGRPDEQRSVATIHAALDAGVTLIDTADAYHREADEVGHNETLIARALASYGGDSSGVLVATKGGHLRPGDGSWTQNGDPGYLKQACEGSLKRLGVEAIGLYQFHRPDPRVPFADSVGALRELLDEGKIVRAGLSNANAEQIRQALEILGEDLVSVQNQFSPSFRSSEPELELCAELGLAFLPWSPLGGITSAAGLGDRFAAYAEIGEAHAVSPQQVCLAWMLAKAPVVIPIPGSSRPETIRDSVAAESLELSAEEIGRLNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>W9E524</accession>
    <name>W9E524_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260468.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2247204_0_0_11"/>
    <dbReference type="OrthoDB" id="2041694at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="104" mass="11804" checksum="A1F52DA082BF9307" modified="2014-05-14" version="1">MNPRLVEIIDALLDAVQRFPQDLNWQPYYEDEQELVGDLRDHAERVGRGDGSRLPELKFELLPTGDLNEIAISSGWGELYLVLANEFDELTPGMTPRPPEPASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>W9E526</accession>
    <name>W9E526_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260487.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.191"/>
    <dbReference type="HOGENOM" id="CLU_031285_12_0_11"/>
    <dbReference type="OrthoDB" id="1746871at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919554" evidence="1">
        <location>
            <begin position="20"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="441" mass="45840" checksum="8A82D8A7CDCB64CF" modified="2014-05-14" version="1">MIASSTRSKRRLLGVCATAAALTLLATACGGTGGGSSSGSAAPKSFSFMSATENTVDRAVLTSLSKNECASENTALPLNVQTQPQANLNEKVQLLAGQNALPTLFHEDTPTTVVQLAKSGKVENLEPLLQKLGVEDQLLPSAVSTVKALYNGQLDALPAEYNIEGIFYNKEIFAAHGLSIPTTWDELVADAAKLNAAGIQPFSASGQQGWPITRMIGDYLFRDLGPDAMSDVADGKAKLTDPEYVSAAQKVADLGAKGYFGKGVGSIDYNTAMNTFLTGKAAMLYMGSWALSNIGDSKQDTVGAANIGFMPFPAVAGGKGSIDQYPSNIGLGIVMSSQNADNTEVDNWISCVAKNYGTDSLKSQNTISGFKVNGSVPAANAVTTQVQTTMSTATSSVLWFEALFSAQATTTSQQDATPLVSGSMSAQAFMSAVQNALNSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>W9DVY1</accession>
    <name>W9DVY1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein, TerC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ActroDRAFT_0022</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 44927</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TerC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260301.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.25"/>
    <dbReference type="HOGENOM" id="CLU_045644_0_1_11"/>
    <dbReference type="OrthoDB" id="1917125at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="PTHR30238:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="309"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ETA71004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="334" mass="36253" checksum="B992A54CE0BEA9F1" modified="2014-05-14" version="1">MHVPVWIWAATVAGLLILIAVDFLVGRKPHEVSLREAAWWGVFWVAAAALFGGGLAWLGHGEEAGAFFAGFVTEKSLSVDNLFVFVLIMTRFAVPPELRQRVLLIGVMLALLLRSIFIALGAAVVASFTWVFFIFGAVLVYTAWKLVTGGGESEEEFHENRLLRRIRRTVPSTDDYRGTRMFVHEGGRRLMTPLFVVVVAIGTTDLLFALDSIPAIFGLTKDPYIVFTANAFALMGLRQLYFLIGGLLDRLVYLSYGLAAILGFIGVKLFLEAMPSVGVHPPHISTGLSLAVIGGVLAVTTVASLTIGRRRQPASTHSDLEPPAPTDEGTRSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW46</accession>
    <name>W9DW46_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260333.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.50"/>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_11"/>
    <dbReference type="OrthoDB" id="1261526at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="226" mass="24072" checksum="30DDC2C69A814071" modified="2014-05-14" version="1">MGSYLITGATRGIGRALVDELADDDLILAARDGNALAALCRTLRAARPMPVDLGRPETIAAAVEEVGLPEHLDGIVHAAGVIKLGRVEELSLKTWNEVFAVNVTAIAELTRLVLPPLRAARGTTVFVNSGAGRAVSGRGNGVYSASKHALVALAEALRLEEPAVRVTSVFSGRTATDMQRELRAYEGEEYRPEDYLRPAVVARIIADALRLPADTTVGDLRVMPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW49</accession>
    <name>W9DW49_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4-hydroxybenzoate polyprenyltransferase-like prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ActroDRAFT_0054</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_800845_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ETA71034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="346" mass="36727" checksum="C41848A93AA71ED3" modified="2014-05-14" version="1">MIQRIRLAFVAARPPVFVLFASYAALGIAQAGRPNAYLPLTGILVTIAGFLIFSVACNDLADEAIDRVNLPGDRRRPLVGGDASRTQLSTTGIIGAIAALAASAALGWLAVLVVAVGLVLSAAYSLRPFRFAERGVLAPLVLPACYVAVPFLLGVDAAHRPVTSHDFVLLGGLYLGFIGRIVLKDFRDVRGDALFGKRTFLVRHGRRATCALSMICWSAGSLIIVIGSTRDTSEGLVADAILGVLAACSVKLINMLSHCSEHRRDERLISAIAILGRGMIVVLLAEFSIYAKAVAPTLALPLLLLLALLTLSQTAAMVVYGPRPRRSDVDRLLSEEPTPVQGLSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW57</accession>
    <name>W9DW57_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260354.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.68"/>
    <dbReference type="HOGENOM" id="CLU_066192_31_8_11"/>
    <dbReference type="OrthoDB" id="2040098at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="67" mass="7265" checksum="598219EC2B72A0F3" modified="2014-05-14" version="1">MPIVVDIDVMLAKRKMSVGELADRVGITPANLAVLKNGRAKAVRFTTLAALCEVLDCQPGDLLRWEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW59</accession>
    <name>W9DW59_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate ABC transporter substrate-binding protein, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260361.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.74"/>
    <dbReference type="HOGENOM" id="CLU_031285_10_5_11"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919856" evidence="1">
        <location>
            <begin position="23"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="419" mass="44774" checksum="37F279E6B33E0045" modified="2014-05-14" version="1">MRSKKIAALAASLALVATAAAACSSSKTSTSSGGKTTLSYAIWDQTQQPAMQKIITAFEQQNPDITVKIQLTPYADYFTKLQTAASGGSAPDVFWMNGPNFQLYAANGQLMSLTSASIKTADYPSSLVSLYTYDNTLYGVPKDFDTVGLWYNKALFKAAGVADPTANWTWADFQSAAAKLTNKAKGVYAVGATLEGQEDYYDTIFQAGGQVISADGKSSGYGSPASISGLEFWTNLIGKGESPSLAQMNDTATIDMFESGKLAMYWGGSWDANAFAQNANTKDNVDVTVLPEGVKRATVIHGLANVVYAKTAHPQQAEKFVQFLGSQQAADIEAGTGTVIPAFNDTQQAWVKSYPQYNLQSFLDELPYAVPYPISKDTAAWNTLEANLLAKAWNLSEPTPTVAAQLATQMNQALAKEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW68</accession>
    <name>W9DW68_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, ribosomal protein N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.83"/>
    <dbReference type="HOGENOM" id="CLU_013985_3_2_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="189" mass="20920" checksum="082FBB2C1D78FD13" modified="2014-05-14" version="1">MTETEISFADKATLVGNLVLLRPVGVADVPGLLELLRDPESARMTGTHMDSEPDARAAEDWYATRAEHDDRLDLAIVERAGGAYVGEVVLNELDPVNRSCGFRICLVGPRAFGRGFGSEATRLALTHAFETVGVNRVELEVYAFNPRARHVYEQAGFVHEGTKRQALRWDGEWVDAHLMALLASDWKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW79</accession>
    <name>W9DW79_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methylamine utilization protein MauE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ActroDRAFT_0096</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 44927</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">One-carbon metabolism; methylamine degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101331_1_0_11"/>
    <dbReference type="UniPathway" id="UPA00895"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030416">
        <property type="term" value="P:methylamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009908">
        <property type="entry name" value="Methylamine_util_MauE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07291">
        <property type="entry name" value="MauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="MauE" evidence="11">
        <location>
            <begin position="10"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ETA71074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="177" mass="18106" checksum="A9715EFB98832E27" modified="2014-05-14" version="1">MYLLLGTRSLLGCVFLVSFVGKAWGRTRYDGYLAATRRLMPRWAASRIPARAAAPGILAAEAAVPVLLAVPASVLAGLALSCVLMAVFAAATAAALRRGENAPCHCFGFSQRELTSGHVTRNVVLAVLALAGVIAGTSSAARPVAAVDAAVVVALAVVFALLFAIADDLADVFRSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW84</accession>
    <name>W9DW84_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding transcriptional activator of the SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ActroDRAFT_0101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260396.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.104"/>
    <dbReference type="HOGENOM" id="CLU_004665_6_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="626"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="626"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="654"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ETA71079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="669" mass="71234" checksum="13DD4FE21E6C4A97" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>W9DW99</accession>
    <name>W9DW99_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Error-prone DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ActroDRAFT_0116</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">DSM 44927</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-C family. DnaE2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450081.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.122"/>
    <dbReference type="HOGENOM" id="CLU_001600_4_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023073">
        <property type="entry name" value="DNA_pol_error_prone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294:SF4">
        <property type="entry name" value="PTHR32294:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="POLIIIAc" evidence="11">
        <location>
            <begin position="10"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ETA71094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="1063" mass="115290" checksum="9BB8E5FBC42F75C2" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWB0</accession>
    <name>W9DWB0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hydrolase or acyltransferase of alpha/beta superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260428.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.140"/>
    <dbReference type="HOGENOM" id="CLU_020336_50_2_11"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="22"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="266" mass="27641" checksum="9A47F32AA97FFA76" modified="2014-05-14" version="1">MPVSALPKPTLARTVRGIGPGLVLAHGAGGSIADNYGPILDGLAAGHTVVGVDWPGTGGSPRSDAPLDADELADQLIAAADAEGLDSFALAGFSLGGPVAIRAAARHPGRISALILTATFAYRDARLDLAAQVWADLYASKNTELLARFLSLVAFSTDALRATDPEALAAGIKALAEAIPPGTPEHVDLVRRIDVREDLARITAPTLVISTSADPLLSPHLHRELAQQIPGARMAELATGHLPFAEKPEQWLALMTDFLAAPESRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWB8</accession>
    <name>W9DWB8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260444.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.151"/>
    <dbReference type="HOGENOM" id="CLU_082565_1_1_11"/>
    <dbReference type="OrthoDB" id="1352255at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025633">
        <property type="entry name" value="DUF4291"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38567">
        <property type="entry name" value="PTHR38567"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14124">
        <property type="entry name" value="DUF4291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="198" mass="23194" checksum="8FB821EB5174D4DC" modified="2014-05-14" version="1">MEEEPRHRIRAHYAADTITVYQAYRPEIGLAAAHDGRFPDSWQRDRMTWVKPSFLWMMYRCGWATKEGQETVLAIEVTRDGFEWALRHACLSHYEHGLHDDRSSWQRTLKRAPTRVQWDPERDLHLQPLPHRSLQLGLAGEAVRLFADKWTVSIRDVTPLAREIHARVVEGDLHAAARRLPPERPYPASEELLAHLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWC6</accession>
    <name>W9DWC6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.162"/>
    <dbReference type="HOGENOM" id="CLU_098677_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009781">
        <property type="entry name" value="DUF1345"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07077">
        <property type="entry name" value="DUF1345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="235" mass="24485" checksum="AAFB3EFFB09916A6" modified="2014-05-14" version="1">MLVSGVCQAYAVTPTSSAPSRATRQPRASARIQFVGSAIAGLFVGVASAVLGAEKVAALIGWDAMALVFGVWVWAAVWPLDPATTAKHAKSEDPGRGQADLVLLSAAVASLAGVGVVVFGAGHAHGAAQYSLAGLALFSVFVSWMLTHTIFALKYARLYYSSGAVGGISFNEDDDPQYSDFAYLAFTIGMTFQVSDTDIQAKQIRRTALRQALLSYPLGAVVIAATINLLSGLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWD9</accession>
    <name>W9DWD9_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ActroDRAFT_0170</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 44927</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.178"/>
    <dbReference type="HOGENOM" id="CLU_000445_89_28_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919345" description="Histidine kinase" evidence="7">
        <location>
            <begin position="26"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="177"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="237"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ETA71144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="461" mass="48554" checksum="28DAB8353043C137" modified="2014-05-14" version="1">MSRRHGGVSLRRRVLTSIVTVTACAVVVFTLPLAWAVAEVYSRGAVVLLQRDAILVSADIAARPTSDPDALIGSDDPSRGVEVGLYSASGRKLAGVGPGRSPVSELSVDGRMHHGIETGHLAVVAPVIRSGRVVEIVRVWMPWDRVTDRRIRAWLVLAVLGSGVVVLSAGLAWHLARRVAAPLEELTAVARALGEGDFTVQAPRTHIREADLAGQALAATARRLGDVLERERGFSTAVSHQLRTPLTALVLGLEAAQNADEAARRAAVGTALRRAESLAVSVEELLRLARETHRSGLAVDAADVARNVANRHEAAVSDAHRRLTVRCESGLAPVRASEAAIAQIIGALLDNALVHGRGEIRLTVTDVGTGVAIEVGDDGPGVAPGGAADEPPVFERGAPATRHGIGLPLARSLAEAEGGRLVMRRRGPRPVFSLLLPVQDREEYEYPPEVSAGGGVGCSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWE5</accession>
    <name>W9DWE5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NB-ARC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0175</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260474.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_317766_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004921575" evidence="2">
        <location>
            <begin position="39"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="NB-ARC" evidence="3">
        <location>
            <begin position="129"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="916" mass="102054" checksum="10FCEA03BF78A4BC" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWE9</accession>
    <name>W9DWE9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase, aryl-alcohol dehydrogenase like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260484.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.189"/>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="18"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="284" mass="29794" checksum="834224CB48A7751F" modified="2014-05-14" version="1">MARSHRVVGAVGVGGLALGCAALSLEHHADPTRGRAVIEAALDAGIRMLDTAAAYTSAAGPNENERLIRDVLAARRSDAARPLVATKGGHLRQGDEFPIDARPESLRRDCEASLSELGIEQIDLYFLHWPDPEVPIEESVGALDDLRREGKIAHIGVSNIGLDELAAARRTATIEAVQNHYSLFDVSGQPVLDQCAEAGIAFLAYSPLRGLAQAEPVLSGSLGRVAGVHGVHAALVALAWLLARSPALIPVVGATRPETARDAAAASQLNLSADELAELNCLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>W9DWG2</accession>
    <name>W9DWG2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FG-GAP repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0199</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260502.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_266080_0_0_11"/>
    <dbReference type="OrthoDB" id="1303819at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004921576" evidence="2">
        <location>
            <begin position="28"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="3">
        <location>
            <begin position="1095"/>
            <end position="1233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="1247" mass="128382" checksum="FF820076DF3BE8A3" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>W9DYT9</accession>
    <name>W9DYT9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.8"/>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="25"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA70988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="416" mass="44134" checksum="264AE8A7F63E8AC8" modified="2014-05-14" version="1">MAVGDTRGARPSGPTVAGSSRAGTAIVVGAGISGLTAAVALRRRGWRVDVYERAPVLEPVGAGIALAPNAVKALDSLGMREWIDQAAVIQGSGGVRRPDGRWLVRTDLGAVAKAFGRPLVVVPRPELIDALRSQLPQAAIHLDTSVEEVLPGDETRLARVRTKQGEKSADLVVAADGIRSPIREALFPEHPGPVYAGFTAWRMIVEAGSHTKVEPSETWGRGAVFGIVPLPGGRLYCYATANLPEGTKFADEHAALLERFADWHSPIPDLIRRTPREALLRNDIYWLDKPLSAYHSGRVAFVGDAAHAMTPNLGQGGCQAIEDAVVLAHELEAEDGGGGLDVAMALNAYTVARRARTVSIARQSARAGRMQQLHAPLGTALRNGAISLAGHLGSGFMLRQMAAVAKWAPPEPPERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>W9DYU4</accession>
    <name>W9DYU4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ActroDRAFT_0011</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">DSM 44927</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260289.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.14"/>
    <dbReference type="HOGENOM" id="CLU_018204_12_1_11"/>
    <dbReference type="OrthoDB" id="357522at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025878">
        <property type="entry name" value="Acyl-CoA_dh-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020953">
        <property type="entry name" value="Acyl-CoA_DH_N_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12806">
        <property type="entry name" value="Acyl-CoA_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12418">
        <property type="entry name" value="AcylCoA_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcylCoA_DH_N" evidence="8">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="161"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="286"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_C" evidence="9">
        <location>
            <begin position="475"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ETA70993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="612" mass="66816" checksum="5DB8DC5B713E5166" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9DYU8</accession>
    <name>W9DYU8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260291.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.19"/>
    <dbReference type="HOGENOM" id="CLU_023194_19_1_11"/>
    <dbReference type="OrthoDB" id="1840839at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="8"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="141"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA70998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="351" mass="37517" checksum="B1D3CF7E4EE7EDE5" modified="2014-05-14" version="1">MAKSSADLRVGLIGFGTAGRFFHAPLLTTTPGLALTAIVTSDPERGGQAVAAYPGVTIVGKPQDLWALGLDLVVVASPNKTHAALAEAALEAGSAVVVDKPFAVTSDQGRALMAAADRHGRLLSVFQNRRWDGDFRTVAHLIEADRLGEVRRFESRFERWRPQLKGGWREQGDRAEAGGLLYDLGSHLVDQALTLFGAATHVYAEADVRRAGAQADDDTFLALTHANGVRSHLWASATAAQLGPRFRVLGSKAAYVTYGLDGQEDELRAGRTPADEDFGSVPPERYGVLGSVDEESPYPTLPGRYTDYYAQMAEALRGDGPIPVDPADAVATLEVIEAARRSADEGLVIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>W9DYV7</accession>
    <name>W9DYV7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative-tyrosine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.29"/>
    <dbReference type="HOGENOM" id="CLU_126482_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="2">
        <location>
            <begin position="74"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="158" mass="16931" checksum="B54CE05DB08C96AD" modified="2014-05-14" version="1">MRGRGLRRPTTPEEAAATNGQGAGGSSGEGAASAAGTVATHRSPDFGLYLLGEQPPEFTWTARWVRWPDFRLPSDRADALDAIVEAWTRAAHERVEVACAGGHGRTGTALACMAVLDGVDPGEAVAYVRAHYDAHAVETPWQKRYVRKFSGRPSSEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ18</accession>
    <name>W9DZ18_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260352.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.67"/>
    <dbReference type="HOGENOM" id="CLU_101801_0_0_11"/>
    <dbReference type="OrthoDB" id="1850406at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021354">
        <property type="entry name" value="DUF2975"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11188">
        <property type="entry name" value="DUF2975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="161" mass="16846" checksum="4270D9F22ADC1E43" modified="2014-05-14" version="1">MGNLVVRALRAVLTVVLTGTCLVQALMVWALATKPVVGSLPLTPLRVATIIGMASVEVAVVCVWRLVTMVRRGTVFSDAAFRYVDVVIGAIVAAALVWFAVTIINAPGQRADPGVTGIMGGIGVAILGVALIVYVLRMLLAQAVAREVEAAQLQAELDEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ28</accession>
    <name>W9DZ28_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2968972_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004923143" evidence="2">
        <location>
            <begin position="20"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="58" mass="6340" checksum="B93288DF6375B7CD" modified="2014-05-14" version="1">MKRSILSHPLTLALISATAALDAVRLPTRSTNSELWRTELPTPAANSIRPKAAGRFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ39</accession>
    <name>W9DZ39_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2044688_0_0_11"/>
    <dbReference type="OrthoDB" id="2086717at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="120" mass="13219" checksum="026C9DCFCF7C5662" modified="2014-05-14" version="1">MLYSPAPAVAEVALAALADDLSQQAHEQFLELLNSLVHGEGTDLPEACERLASRGIWLLYRELALDRSINATATAFELLATLEPDRDRLRRAQIALGESLPWDYRPGMLNDPLDSSATDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ51</accession>
    <name>W9DZ51_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ActroDRAFT_0100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028723_10_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="5">
        <location>
            <begin position="25"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="5">
        <location>
            <begin position="118"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ETA71078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="164" mass="17622" checksum="A7CEE2AF92E509EA" modified="2014-05-14" version="1">MQGTWMSILIATSITVPALAIGWYAVWVLRRRLVVVDVHGASMEPTLRQGDRVLVRRIPAESVRTGDIVVIERSGAGAAAEQPLQLDRLDRRRDWAIKRAAAVAGDPVPASVAAAAGVTPGTAVPAGFLVVLGDNPSRSADSRVWGYLPTERLLGVVRRRLDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ53</accession>
    <name>W9DZ53_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450077.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2010376_0_0_11"/>
    <dbReference type="OrthoDB" id="2052421at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="123" mass="13132" checksum="BF8129DBBBC44EEE" modified="2014-05-14" version="1">MREIEEPPDTLNGRRLYVPMRESGCGVRLALFRDRHGARCAVGFTDAGALQRVLGPDYTVLPLARRVLRELAAARGVEQIQVDPVFAAAPVARPARRMDPQMAGALAVCAAAGAAAALLGELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZ79</accession>
    <name>W9DZ79_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type antimicrobial peptide transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ActroDRAFT_0137</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450088.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="28"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="302"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="61"/>
            <end position="68"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ETA71113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="337" mass="36053" checksum="B27ECFF129ECC6E3" modified="2014-05-14" version="1">MPSQLHRLEAAANRPSEVYGGDAHVVCDRVVRIYQTEEVEVVALQGLDLLVGRGELVAVVGASGSGKSTLLGILSGLDAPTAGRATVAGFDLAALGKRDRLRYRRSTVGFIWQNTAKNLLPFLSAADNVALPMAFAGGGKRERHRRALELLDLLGVGECRDRRPAQLSGGQQQRVAIATALANRPEVVLADEPTGELDSATAAQVFEALRGANCELGVTILVVTHDKAVSEHVGRTVEIRDGRISTETLRAEVESGGEGAPAVRAEQYAVLDRAGRVQLPRDYTEAAGLRDRVRLTLDPGHVGVWPGHVPQPQRTPPQTQTPIEPETRAAREDASDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZB2</accession>
    <name>W9DZB2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Carbohydrate ABC transporter membrane protein 2, CUT1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ActroDRAFT_0185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 44927</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260490.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.193"/>
    <dbReference type="HOGENOM" id="CLU_016047_1_2_11"/>
    <dbReference type="OrthoDB" id="1584669at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="88"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ETA71158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="295" mass="32649" checksum="E41C7950361601B4" modified="2014-05-14" version="1">MSTDTPTGTRIQAHPAGRKRRFGPGKLTVRFLITVLILVEVLPMIWMFLTSMKSNSDYLNNSAWSLPTHWLWSNYSTAWTTGSIGLYVRNSALAVFPSLFLLLLLGTAAGFALQIMVWKGRNFTLLIFLAGLMVPVQMILLPLFTVYTQAGISGTLWPLILTYTGANLPLTVFMMSTFYRAVPREMFEAATLDGAGILRSFWAISVPMVRNAILTVGLVEFFFIWNDLLVALTFTNNQNLSTIQVGLLNFTGQFGSTQYGPLFAAICINVFGTLLIYLFLNQKIMKGLTGGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZC0</accession>
    <name>W9DZC0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0198</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034272439.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.206"/>
    <dbReference type="HOGENOM" id="CLU_020979_0_0_11"/>
    <dbReference type="OrthoDB" id="835401at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="540" mass="60129" checksum="006E0C9813F8893D" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZC4</accession>
    <name>W9DZC4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3303456_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="39" mass="4217" checksum="DCEC5A5C8BEE39C8" modified="2014-05-14" version="1">MRQEPWITLSPRAHGAVGALTATTQFNGRIYLTGLEGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZD0</accession>
    <name>W9DZD0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046116_2_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA70985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="487" mass="54025" checksum="32766436EFE7D615" modified="2014-05-14" version="1">MMPCREEPGQSRAAGGGGSLKVLRGFRAGVHGCFARRADSLFDLVDAVLATDGRVRSLAELSLQRPFRRGHGALYDAVASGEIDVPALAGLITSVWEPLDDGPLKFAIDVSSWHRPHAECARERHHCHHSCACGNRRGTVPGWPYSVAVGLEWGAHSWCAPLDARRLAVAEDATAVTVAQVEAVLERCAAAGLSHGRPAALFVFDSGYDLTRIAYLTAGRGLERQILGRVRRDRVYYGDPVPRPRGAPGRPPVHGRRFAIADPGTWHDPDLRVERDSPRCGRTIVTAWHGLHQKLERQGAWREHAQQLPRLPGTLIRVQTQRLPGGRAPQDLWLWHHARPGTGFDLDQLWTAYLRRFDIEHTFRFFKQSLGWTAPQVGTPEQADRWTWLTITAYTQLRLARRLGAHLRLPWQRPTPPDRIPTPGRVRRGFPVLARKIGTPAAKPKPTTAGPGRPTGTTRPPRTRHPAGKKTGTSHERATSKTPDHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZF2</accession>
    <name>W9DZF2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260303.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.26"/>
    <dbReference type="HOGENOM" id="CLU_773007_0_0_11"/>
    <dbReference type="OrthoDB" id="1654916at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="358" mass="37772" checksum="E44458935E789ED3" modified="2014-05-14" version="1">MGDQPHEDQPTVPAWAVPPAQPEPTAPLPGFPFAPPQQQPGAEPGPGASWPGADGGYGGGYSDPGAQYASYPAGYPTGPTPPRQNGARTAVAIISALAVIGTAVTAVIYSSGSNKHQTPVSFQNTDPLPTRSGAPLISASPEPSDQTSTQASPDSSDEFDSPTADAFDWDALNDSGTDPTPFTQDALLMHSFTDSQNITYTLEAAGEKKCVQSTMSKSVQNVLNEYGCKNAMTGSYVVDSSVDKVESNNDILVSVQIWPFPDAATADKAEKALAKASSKQFSIWCPDSGPGAAPCNSQNYYTAATWWSLQSEYRYVVEATAVYTNMTQDTSVAYKWEKTATAEAVKESGPQVYADDQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZF7</accession>
    <name>W9DZF7_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260313.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.31"/>
    <dbReference type="HOGENOM" id="CLU_051795_1_1_11"/>
    <dbReference type="OrthoDB" id="1086845at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009218">
        <property type="entry name" value="HD_phosphohydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21174">
        <property type="entry name" value="PTHR21174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035170">
        <property type="entry name" value="HD_phosphohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="39"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="208" mass="22936" checksum="13960F31CB7D9A55" modified="2014-05-14" version="1">MSEATIEAWMALTGAEHARPAGEDLLARYAEPHRRYHTLKHLDEVLAIVAELSAEAQDADAVRLAAWFHDAIYTIGSSSGVSNEEASARLAEQVLGELGIPAARTAETARLVRLTQAHKSEPGDRNAAVLCDADLAILGASPERYRQYALEVRQEYAEIPDEAFRRGRAEILRSLLEEPTLFRTAAARERYEEPARKNLTAEIDALTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZG2</accession>
    <name>W9DZG2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.36"/>
    <dbReference type="HOGENOM" id="CLU_122293_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="183" mass="19509" checksum="0A37B5A264D2F079" modified="2014-05-14" version="1">MPAAVRLARGQGFDYSCLPEHGELLRVLARGVGAGRIGETGTGCGVGLAWLSAGAHQDAQVVSVERDPERAALAAELFDARPNVEVVQGDVSRLRKYGPFDLLVLDGGGQGKGPDDGPIDPAQWLAPGGLIVMDDFSPLTSWPPRFGEAVDLPRLHWLAHPRLRATQVRVTPEWSALLATYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZG7</accession>
    <name>W9DZG7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uroporphyrinogen-III synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034272303.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.41"/>
    <dbReference type="HOGENOM" id="CLU_011276_9_1_11"/>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40082">
        <property type="entry name" value="PTHR40082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="295"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="295"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="408" mass="43912" checksum="0E7BB86C657DF2D5" modified="2014-05-14" version="1">MTRAVPVLAEQPLLGLTVAVTADRRREDLTALLRRRGARVLEAPTLRLVPLEDDAELRAATGECLREQLDYVVATTGRGWRGWISAAEGWGLAEELDRALHRTVVVSRGPKATGAVRASGLREEFSAASELCSEVRDYLIGRGVAGKRIAVQQYGSLDPGADCDLALELRAAGAQVVAVPVYRWVEPEDKLAVDRLVEAIVAREVHAVAFTSAPGVSALLDAAAARDAVFGRDRVLAALREQVAAACVGPVCAGPLLAHEIPVIQPDRARLGALAAQICRDLPERMRQEIAVEQGRTLIIQGNAVLVQAEREPDVEHPDPDPVLLPPLLAAVLAALAQRPGWVLSRAELLRRVWHPRPLGGSAVLAPGPQRDQHLVESTIARLRTALGEHGDLIRTVTKRGYRLAADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZM8</accession>
    <name>W9DZM8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ActroDRAFT_0066</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260357.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.70"/>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ETA71045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="335" mass="35358" checksum="D051ED27BC1383C1" modified="2014-05-14" version="1">MATMQDVADRAGVTKQTVSNVMGNRGRVGRETAARVRAAVKELGYTPNLVARSLATGTTKTLGMLVPTLSGGFYSVLVEEVEDVLNRHGYHLLLCTTHLDGERARRHLAGLSSRNVDALLIAGDQDLPTQLPVLAEAPFPVALCAWETEAPDGYPVVTIDYERAGCLAGRHLRELGHERVAVIASPAHGARIEGFRRALAADGIVLADDDVHFAPEPTSTGGFLAAQAAFTADPEVTALFATHDILALGAIDAAKESGRAIPGDVSIVGHDDNDEASLARPALTTVAIPKREMARLAAEQLLRILAGAEEGTNSLHLLRPSLTVRASSGPVRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZN6</accession>
    <name>W9DZN6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ActroDRAFT_0076</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260369.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037628_6_1_11"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ETA71055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="341" mass="36364" checksum="7A24C8E81CB9ED0C" modified="2014-05-14" version="1">MAVTIADVAKLAGVSRSTVSYVLSGARSISPDTRRRVERAIEELQYRPHAGARSIRSGRNGVIAMALPMVHGPQNQVQMPYVWAALTAAQDLGFKMLMLTDDDGEAAIRDSVVGSQVDGVMLMEVQRKDPRVALLGSLKCSAVLVGTPDDSARLPYVDFDTGLAGRLCAEHLLELGHRGVGYIGQSSATFRRGVAYAVHARDGALSTLRAARARTAWTACDGQPGDVVRAVDQLFAKVHDLTGLIVYNERALPLVLDRLAGLGLRVPHDVSVVAVCPDDEAERLHLPATSASLPVEELARTAVRLLAGQVNAEPVASVTILPPTLKIRDTTGSAPSRSERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZR0</accession>
    <name>W9DZR0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0102</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260397.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2766615_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="69" mass="7246" checksum="4B829BFC03172A38" modified="2014-05-14" version="1">MTTAMRSFGDRMLGALLGKEVAAAVYCPHSGPTCATSCYSHGVTGCEYICETDCYAAAVLCWTHSACSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZR4</accession>
    <name>W9DZR4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260404.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.111"/>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="287" mass="30365" checksum="F6CCC6DD5A224708" modified="2014-05-14" version="1">MEFQQLRYVIALAEEASFTRAAARCHVVQSALSHQIKALENELGVALFARTSRRVELTSAGQAFLPAARASLEAAERAADDAAAASGLVRGRLSIGVIPTVTAIDLPAALRTFRQAHPQVKIVLRVAGSDELETAVTGGELDIAVLGLAAGRKPQAVAWRNLGTDRLVAVVSRDHPLAGRKRVSLEDLSGETFTDFPSGTPGRAQSDLAFTAAGIHREVAFEALATDLMIGLVREGLAITLLPSRYVPADPALATIKITDGPTRTEYLAWNALNPSPAAQAFITTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZR9</accession>
    <name>W9DZR9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hemoglobin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260411.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.117"/>
    <dbReference type="HOGENOM" id="CLU_1056431_0_0_11"/>
    <dbReference type="OrthoDB" id="1101420at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABM" evidence="3">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="258" mass="29397" checksum="2323D80788976476" modified="2014-05-14" version="1">MTVEYIRYQIPAEAAEGFEQAYGRAAGQLAEAPECVDYELSRCDEDLESYILRITWTSTAGHLQGFRASEHFPPFLEAIKPYISNIQEMRHYTPTAVAGQGGSIPSLYEWLGGAEALERLTRSFYGEVLKDELLYPLFKDMDEHHPHFVALWLGEVFGGPENYSTERGDYRHMVSRHLGKHITEQQRRRWVNLLMDAADRVELPTDPSFRAAFASYVEWGTRLAEINSQPGREAYDAPIPHWGWGVAPPYKPAAKSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZS4</accession>
    <name>W9DZS4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleotidyltransferase/DNA polymerase involved in DNA repair</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0117</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026357_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="3">
        <location>
            <begin position="27"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="511" mass="53698" checksum="77E9FC60F7EF8601" modified="2014-05-14" version="1">MLAAWAPAFTVLAAGAALDELAATVAAGRVTAVTPAAARAGVRVGMRARDAHRICPQLAAYRADSERAARVFEPVVCALEEVAAGVEVVRPGLCVLLAAGPVGYYGGEEQAAGVIRDAAAVVECELGPVAVGVGVADGMAAAVLAARTDTLVPPGGSRRFLAEFDIAALADAQLAQQLRRLGIRRVGQFAALPASSVATRFGLVGLRAHRLARGLDARDPAPRRAPRELSVVREFEPVPTVEPLVFAARGLAEQLHEKLAGLGLVCDRVEIEALTGDGRGSARWWRHEGRLSARAVAERVRWQLEAWAQRNPPPAGHDPHVESGEGFVSLSLRPDGLRIATGTQIDLLGGVAQLPETAEAAIERLQDLLGHTRVARPVLSGGRGVGEQIALVPFGDLDPESRGTGPWPGRVPEPAPAMIPGRSTPVRLLDAAGNTVVVTARGEMPDPPAVLEVGAVCADVTGYSQPWPVHERPWDEDGGRRYARLQVTTADGHAYLLAAEAGSWYVLAGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZS9</accession>
    <name>W9DZS9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1105305_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="251" mass="26437" checksum="8F13709B1688C59C" modified="2014-05-14" version="1">MRKDSASPSRVARSFSPTSTPGSAPECPENSRIFLFRRKPDPRLLSVVASSMEESGGSARATGGMVDGMAARTASGVWPKAVQELPSACDRATRSCAVREHRADPTGAMQNSTAGTTGVPTPPRGSRIRLAGPGRCRILPDRTRPACGILQRGLGSGWIARGRRRISHQARPEHRRLRADQGSGWSDQGDAESFRTEHDRATGRDPARAQLTPDLRGCALSSVGQAKPGQGSAGRSSGAMHNPPPATATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZT8</accession>
    <name>W9DZT8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent oxidoreductase, NADPH:quinone reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260430.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.141"/>
    <dbReference type="HOGENOM" id="CLU_026673_3_3_11"/>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="310" mass="32783" checksum="0C2704B2E8D69A2D" modified="2014-05-14" version="1">MRAISQRSFGEPAVLQPVDLPTPVPLPSEVLVRVRSTAVNPVDAMVRSGTFRMLGEPPFVLGWDISGVVEEVVPGVTRFEVGDEVYGMPFFPRAGNAYAEYVAVPSRQLARKPTTIDHDHAAALPLVGLTAWQALVDSANVRPGQRVLIHAGGGGVGHLAVQIAKARGAHVTATASAAKQDFVRSLGADEVVDYRGTDFTEKVGDLDVVLDTVGGPVGPRSIGVLRPGGLLLTIVDRTDTALRAATISAGRRFAGVTVEPDYVGLEALAKLVDEGRLMPFVEHTLPLEQAAVAHELIESGRTQGKIVLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZU7</accession>
    <name>W9DZU7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260446.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110577_0_1_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015068">
        <property type="entry name" value="DUF1877"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035944">
        <property type="entry name" value="YfbM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08974">
        <property type="entry name" value="DUF1877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111069">
        <property type="entry name" value="SSF111069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="166" mass="19094" checksum="320A8ACA4208FCAC" modified="2014-05-14" version="1">MSMIGEYLRVTPSELSRAIEDPQWALDHAEQIQDAQDENEQSPKEAKHFSTYKTWDMLGFLLRRFHFPVDVVHGEEDFADDEDWGYGPPHFLTVERVRHAARELARTSYDDLIRDVDHTELAAANVYPLSWDSPTSLEWARDYYGQLTAFFSAAADAGDAVLVWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZW2</accession>
    <name>W9DZW2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0166</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.175"/>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="293" mass="31103" checksum="21C5A3CD941B5C4D" modified="2014-05-14" version="1">MGAWTVELRQLEHFVAVAQECHFTRAAQRLHIAQSGLSASIRSLEKELGATLFLRSTRQVQLTAAGQALLAEALRALSASNAAKEAVAAVQGLLRGSLSIGSLQCLHAIHLPTLLSGFLGRHPGLEIRLRQGGSDELVEHVSTGRLDIAFVSRPARLPENVAVSPLDAEDLVLACAPGHPAATKDRAKLQDLTDEQFVDFPPTWGTRDHADRVLAAAGVERRVALEVTDVHSLLDLVACGLGVALVPTSFAGKTKQVRFIPLDGDVPAWELVTITGDPPSPAATALLRQVCGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZW6</accession>
    <name>W9DZW6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260466.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1727455_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="151" mass="15308" checksum="D175BC310180AEB2" modified="2014-05-14" version="1">MAARKASRGADITEDPDLRNPTSNCNEIQRVTLVAAPVVKQLASKSTSTIQLPGAGYAATTGRGVLAALAILAGLLPLLGRITRPQTARFERFTASDRRLRNALASGLAAVALTAAVSACSSAGAGSATSTPSQAVSRCCDAATSGQNEPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9DZW9</accession>
    <name>W9DZW9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NB-ARC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_365487_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_16" evidence="2">
        <location>
            <begin position="75"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="763" mass="83075" checksum="2C84B4E6627F1E86" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4B2</accession>
    <name>W9E4B2_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ActroDRAFT_0004</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 44927</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260277.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.7"/>
    <dbReference type="HOGENOM" id="CLU_002346_0_2_11"/>
    <dbReference type="OrthoDB" id="245411at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901575">
        <property type="term" value="P:organic substance catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023230">
        <property type="entry name" value="Glyco_hydro_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="DUF4981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00719">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bgal_small_N" evidence="8">
        <location>
            <begin position="706"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ETA70987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="993" mass="109424" checksum="F8D18CCEAE47F218" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4B7</accession>
    <name>W9E4B7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent oxidoreductase, NADPH:quinone reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260287.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.13"/>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_11"/>
    <dbReference type="OrthoDB" id="831053at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="14"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA70992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="328" mass="33677" checksum="757CAB2D0EB76989" modified="2014-05-14" version="1">MRAWQALAQGEPEKVLSLAEIPVPEPGPGQMLVRVRAAALNFPDVLLCRGDYQIRPELPFTPGVELCGEVTAVGDGVDPGRVGSRVIGNPVLPHGALADFTLMHTAEAFDAPESLDDAEAAALHIAYQTAWFALHRRAGLKPGETVLVHAAAGGVGSATVQLAKAAGARVIGVVGGPEKAQVARELGADLVVDRTTEDFVGAVKEATGGRGADVVFDPVGGAAFAGSTKCIAFEGRIVVVGFAGGTVPAPPLNHALVKNYSILGLHWGLYKLRDPASIVAAHEELCALADQGVVKPLISERVGLERAPEALAALGAGSTTGRVAVLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4C1</accession>
    <name>W9E4C1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-glucanase/beta-glucan synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.18"/>
    <dbReference type="HOGENOM" id="CLU_019533_4_1_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919522" evidence="1">
        <location>
            <begin position="46"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="48"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="329"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA70997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="456" mass="46585" checksum="78D95F0A4EEEF2E6" modified="2014-05-14" version="1">MFRTRFTARSAPDRTVRTRISAPALRRVAAVIAAISLGLLTDVFALGTSASATTVPGPPSGWSTVFSDSFSGSSGSGIDSQWMYDTGAGSTFGTGEIETMTNSTSNVHQDGAGHLDITALGSGGNWTSGRVQTTSANVGAPAGGELEVTASIQQPTGGLGYWPAFWMLGPGQWPENGEIDIMEDVNALSEVSGTIHCGTDPGGPCNESNGIGSGLRACSGCQSGFHTYTMILNRTNTSAESITFYLDGASYFTVNESQVGTSTWQAAFDHNLSIILDLAMGGGYPNGVCGCTSPTGATSSGGTMSVAYVAAYSTSSGSSGGGGGGGTGASGTGPITGYQGLCLDDRSASTALYNPVQVYTCNGTAAQQWSVVQAGSLIKVFGMCLDVDAAGTADGTKVDLYTCNGTGSQVFIPESNGELYNPQSNKCLDDTAYGGSGTQLQIWDCADTANQQWKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4C5</accession>
    <name>W9E4C5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protease subunit, stomatin/prohibitin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260299.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.23"/>
    <dbReference type="HOGENOM" id="CLU_053998_0_0_11"/>
    <dbReference type="OrthoDB" id="1213601at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="66"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="298" mass="31661" checksum="9B2922E41BD03BF5" modified="2014-05-14" version="1">MSTGAVGAAGTPQQIQEREIGSAPGVPLLVFGVALGVAGIVLIKQHETATIWGGAGLIVVAALVLAGLNAVAPGQARVVALFGRYQGTVRVTGLRWVNPFTVRKRMSTRIRNHETATLKVNDADGNPIEMAAVVVWQVADTAKASYAVEDVRTFVTTQAETAVRHIAGHYPYDARGAERISLRDNADQITTQLSDELSQRVAAAGVAVVESRITRLSYAPEIAQAMLRRQQADAVVAARERLVEGAVGMVRTALHQLSEEGLVDLDEERKAAMVSNLLVVLCGDQPAQPVVNAGTLYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4C9</accession>
    <name>W9E4C9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosylglycohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.28"/>
    <dbReference type="HOGENOM" id="CLU_024566_5_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="308" mass="32601" checksum="DE6E6E0BBF10534D" modified="2014-05-14" version="1">MHVRLAAMTDDRRNRAVASLRGLAVGDAFGSCFFVPENYDALVARRLPADPWRWTDDAEMACSIFAVLDRLGEVDQDALAASFAAHHDFDRGYGPGVNRMLRLIRQEGGDWRKLVAESWDGRGSWGNGAAMRVAPLGAYFADDPERAAAQAAASAEVTHAHPEGLAGAVAVAVATALATTRPRVEGAQWLRDVAAHVAPGLVRDGIANAISLLPLEDSQSAAATLGNGREVSAQDTVPFCLWIVAKHPDDYVEALWATAVAGGDIDTTCAIVGGILGARPGRGQGGVPDGWLRRCERLPDWAGVDDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4D2</accession>
    <name>W9E4D2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260315.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1559674_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919444" evidence="1">
        <location>
            <begin position="35"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="171" mass="16917" checksum="D875FA169F3E3987" modified="2014-05-14" version="1">MVLLHKLHPIAAMAAASGAAMALSLVAGCPSAEAAAAPADGSAVCAASFPIALNGFAFTPATVVPGGSATADLITTNCSNAAVDTTEMWSGQWLPLSSSGALPTGCPIIDPLLRAVDYRAGQEVAENTVYTVPTGCHAAELQVTVRITGSNGALGLTATAVLDIVQITPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4D8</accession>
    <name>W9E4D8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAD-dependent aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ActroDRAFT_0035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260321.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.38"/>
    <dbReference type="HOGENOM" id="CLU_005391_0_2_11"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="35"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ETA71017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="507" mass="55063" checksum="D9987180F960D3D2" modified="2014-05-14" version="1">MTRFAAPGTADALMSYQNRYDHWIGGESRPPAGGKYFENPTPVTGAAFCEIARGTAEDVERALDAAHRAAPAWGRTSPAARAEILNKIADRMEGKLAELAVAESWENGKPIRETMAADIPLAIDHLRYFAGAIRAQEGSLAELDEDTVAYHFHEPLGVVAQIIPWNFPILMAIWKLAPALAAGNAVVLKPAEQTPASIHYLMSLIADLLPPGVVNIVNGFGVEAGKPLASSARVAKVAFTGETTTGRLIMQYASENIKPVTLELGGKSPNIFFEDVSRERDDFFDKALEGFTMFALNQGEVCTCPSRALIQRGHYDEFMAEAIARTERIVQGHPLDTATMIGAQASNDQLEKILSYLDIGQAEGAKVLLGGERVDLGGELSGGYYVQPTIFEGANHMRIFQEEIFGPVVSVAAFSDFDDAIRIANDTLYGLGAGVWTRDSAQAYRAGRAIQAGRVWTNCYHLYPAHAAFGGYKGSGIGRENHKMMLDHYQQTKNLLVSYSPKAMGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4E1</accession>
    <name>W9E4E1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H-nitrite reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450064.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.43"/>
    <dbReference type="HOGENOM" id="CLU_003291_4_4_11"/>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="422" mass="43158" checksum="3FF0C209A4E1B7F8" modified="2014-05-14" version="1">MSLGHICVVGDGLAGNMFARRLLTYLPQAQITVFGADTAPAYNRVLLPDVLAGRTDRSLLALPTPEGPGLRLRTGARVSRIDRAAKTVTTASGDSEHYDTLVLATGANPVLPALTGLRDPSGPGGLREGVHTLRTLADLDGLRPAALAAHRAVVIGGGLLGVQCARALISLGPKVELLHQGPHLLDHRIDDVAGAILARTLRGHGVEVHTECRVRGVITADGVADGPGPARGVRLADGVTLDCDLVLFACGAAPASAPAVAAGLAVRPSTGGVIVDDWLRTVTDTAVYAIGDCAAPISGAWPGLAAPALAQAEFLAARLAGRPTRTPRYQGAGSVIRLGGDGLDLAVLDAHEPLERPRTVRLVDPVAGTYRSVTVGGGRLLGSVLVGDVSAAAHLSHLLTRPGPLPADPLDLLIAPVKGSHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4F0</accession>
    <name>W9E4F0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase AhpD family core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260329.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.48"/>
    <dbReference type="HOGENOM" id="CLU_082760_6_1_11"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="11"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="149" mass="16276" checksum="316855D3CA5D571E" modified="2014-05-14" version="1">MQARMETTVNPDVVNAIQLLSKAVRSSGIDQKTTELVHLRVSQINGCSPCVYAGVAQAKKLGETDERLHAVAVWRESPFFTDAERAALDLAEAATRIEDGQPGVDDETWQAAAEHFAPAEISSILLCVALTNFFNRINRALRTPAGKVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4F8</accession>
    <name>W9E4F8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase, histidine kinase/DNA gyrase B/HSP90-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.60"/>
    <dbReference type="HOGENOM" id="CLU_042141_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045975">
        <property type="entry name" value="DUF5931"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19354">
        <property type="entry name" value="DUF5931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="303"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="410" mass="42725" checksum="47D1257E10ADC4C7" modified="2014-05-14" version="1">MSPESASPPRPLRVAAAALAARVERTPVDGVSALLWRAVSMFRLLSCAYAVTLTVHYGHNYAHPVGGYAVAVAMALWSVASILGYARYRPAPDRRTRPALPPLLVADLVVTLGCLLATRWIVPPGQNPQILPMLWVASVVLAWGVVGGSGAGTAAALALSVGDVFVRDNVNEGTLNLAILILLPGALIGYVADLATRVEEQSRRAAHLEAATIERERLARAVHDSVLQVLALVQRRGAEIGGPAAELGRLAGEQETALRALVAIGPLSRTPAGTSDLCSALRAFEAPRVTLALPAEPIALPSVDCAELAAAVGAALDNVIKHTGPDTRVWILAEAGAGTVSVTVRDDGPGIEPGRLEKAEAEGRLGIAQSIRMRTIRLGGTVSIVAPPGQGTEIELRLPMRSVSIEEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4G2</accession>
    <name>W9E4G2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.66"/>
    <dbReference type="HOGENOM" id="CLU_037742_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="416" mass="45187" checksum="7DF7E6A2F86D15C5" modified="2014-05-14" version="1">MMSAPTVTLRNMAHGTEMRTVVDGEVFVHYGQIYVNSDPDSFGPELKAAFAGQSVGLCGGADPGALWLVTGLHTGNVGFTVEVHDQPPLLDPAWEEAVEVSFRPASGRSLLVQWAGSAAWELGLDEIDYRVRYCAQGMEGARLKDTRTHGPQLDRYLLQFWPAPPEPERLLRRTSSVAEYWHEFARKQPPPPTAAERAEAERVARETQEQADEQARTAREEWKWGGKLPSERLRQVSGCVESLLRFDPELVHALDAAGPAAQRSVALLAARRACEAAGLAGVGWIAAALDALEAGDALPPPFDDRDRLHRAIRADPDLPRQTVGRAIPPQRPAFQPPLPSRAGRGEPLRLSTSSRRPAPAPAIRISQRHMALPAVVHAAEADPLEAAVKAVSAAVSAYGENYPALLAEVRATVRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4H2</accession>
    <name>W9E4H2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0083</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_063627903.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.86"/>
    <dbReference type="HOGENOM" id="CLU_012501_3_0_11"/>
    <dbReference type="OrthoDB" id="1281138at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="SSF50370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004920048" evidence="1">
        <location>
            <begin position="28"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="3">
        <location>
            <begin position="85"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B-type lectin" evidence="2">
        <location>
            <begin position="416"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="543" mass="53428" checksum="E764679E599ABB98" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4I3</accession>
    <name>W9E4I3_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Diaminopimelate decarboxylase</fullName>
            <shortName evidence="3">DAP decarboxylase</shortName>
            <shortName evidence="3">DAPDC</shortName>
            <ecNumber evidence="3 4">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysA</name>
        <name evidence="8" type="ORF">ActroDRAFT_0104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 44927</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="3 4"/>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.108"/>
    <dbReference type="HOGENOM" id="CLU_026444_0_1_11"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3 4" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="7">
        <location>
            <begin position="60"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="6">
        <location>
            <begin position="317"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="3">
        <location>
            <begin position="309"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ETA71082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="454" mass="48523" checksum="825147449CDA0D72" modified="2014-05-14" version="1">MSLRVELLGEESDERETGAVLGSPWPAGAREQAGRIVVGGVDLGELVERFGTPLYVLDEAEFRSRAAAYARALPQDSVRYAAKAFFSPTLARWVREEGLGVDVCSANELALALDAGFEPERIVLHGVAKTHEELETATREHVGRIVIDGFTEIAHLASLAGRHRPYQPQGVYVRVIPGIAVGHHEAVRTGIEDQQFGLSLADGSALDAVTRILGQAHLRLCGLHCHLGSQISTIEPYLTAVDRLTAFLAELHVRHGIQLPELDLGGGQAIGYRPGDASLRPGEFAAAVTARLRERCAEHGLAVPRLVIEPGRSIVGPAGIALYRVLAVKTSAHGIRFAAVDGGMSDNPRPALYHAAYTIRPVAQHGGAPLRPTRVVGRHCEAGDVLAPEAQLPEDLRAGDVLAVPASGAYQLSMSSAYNLVGRPPLVAVRDGLARLIQRRETLADLTSREGAWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4I7</accession>
    <name>W9E4I7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Geranylgeranyl pyrophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0109</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.114"/>
    <dbReference type="HOGENOM" id="CLU_014015_2_1_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="363" mass="39120" checksum="902D0B8350AD6CA7" modified="2014-05-14" version="1">MIASVGSPGVPVLDLDLFRARVEARIEQFLDAKARAVDTQRLPAPAVESLRAFFRAGGKRLRPLICACGWLAARGGRETASLIRVGAALEMFHAFALIHDDVMDRSDRRRGRPTVHRLLESDFSRSHPAGDSARLGESAAILVGDLSLVWSDELVHTAGLEPAVFMRVLELIDRMRSELMFGQYLDLTADARNGAGPELPLTVIRYKTAKYTVERPLQIGAALAGAGEGLLADLSAIALPLGEAFQLRDDLLGTFGDPEVTGKSQLDDLRAGKYTALIALALGDADPGQAAVLRGVLGNEAISDADADRARQVLDETGAAARVEQMIADRYRRTLTALDRAALPADADQALRSLAHDAVWRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4J1</accession>
    <name>W9E4J1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260415.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.126"/>
    <dbReference type="HOGENOM" id="CLU_103066_1_0_11"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-1" evidence="1">
        <location>
            <begin position="5"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="167" mass="17713" checksum="76DD8CDCAA350751" modified="2014-05-14" version="1">MEATSTALVVQPGEAGKASLTDGAFELLADGGAVSASRLTLATGADGAPPHHHKLSHEVFYILDGTMVFRLGDRVTSVGRGGLVIIPPNLPHAFGAAQGSTVDVVVLLSPGVERFAYFEQLGAISRGEAEFDSLIPEQDRFDVHLVDLPDWRTAPSSQHVQHVQPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4J2</accession>
    <name>W9E4J2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_1_1_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="133" mass="14201" checksum="026FAF601366255F" modified="2014-05-14" version="1">MAELLASLVGQAILFNEQVARALGIGAVDLQAFGVISRYDGPISPTEVAARTGLPASTTTRVLDRLEQAGYVVRSAVPGDRRKVGVEVVQEKAAEVARHYLGKVQQIKKLNAKRTDAEVAAVTSYLSELTARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4J6</accession>
    <name>W9E4J6_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type antimicrobial peptide transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ActroDRAFT_0136</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260434.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ETA71112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="236" mass="25270" checksum="491C737DC7E61D8D" modified="2014-05-14" version="1">MTELADPSEVMVSARNLRRTFGSGDRAVHAVNDVSFDIPRGQLCAVVGRSGAGKTSLLNLLGGLDRPDSGSLSIDGKQVFGDGLRPSRRELTALRRDTVGFVFQNFSLLPILNAAENVGVPLRVRRTPAAEREDRVSLLLKLVGLGDHRAQRPGELSGGQQQRVAIARSLVHTPRLLIADEPTGQLDSQTGRDVMELLHAVVLSENVTAIVATHDEAMIELADRVLTISDGALTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4J8</accession>
    <name>W9E4J8_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2490854_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="86" mass="10058" checksum="F1C5EB8B54872B90" modified="2014-05-14" version="1">MTPALLGLAVNQWTSARHLDLGGYDRLTPVYVEYEGWFVDRFLPRHMLLHRPCIIVGAFLLMYYKAPELHLAHAGADVLNWFVWRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4K1</accession>
    <name>W9E4K1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450091.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1335183_0_0_11"/>
    <dbReference type="OrthoDB" id="1994132at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="205" mass="22207" checksum="92F6D50FEEE2E21E" modified="2014-05-14" version="1">MATDRPSGQAGPANLHADGYAPDAPSRPLIPRWCSVLLLALGAVTLPWTAGLAVVLPSSERTAHYDVSWAGFDLMLCALLLYTGWNTLRRREQSELSAAMTGTLLIVDAWFDVLGAPDTDQFLTALAMALLVELPLAGFCFWITKHVDAVRVQRESALSHSLRRVAQRTHSALKPHSASADDGHGPAAAKSGTRQKSESARRRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4K7</accession>
    <name>W9E4K7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative acyl-CoA transferase/carnitine dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033975_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="411" mass="44352" checksum="C6F33CF22535F55D" modified="2014-05-14" version="1">MTTQPTQTDGPLSSMLVLDLSHALAGPHAAMMLGDLGARVIKVEAPQGDETRGWGPPFVVPPVVGASPESTYFLACNRNKKSVVADLQSREGKELVERLIRRADVLVENFRPGVLDRLGFGPERLKELNPLLVVLSISGYGHEGPDDDRPGYDQIAQGEGGLMSLTGESGRPTKTGVPIADLLAGVFGVCAVLAALIERRSTGHGQTVRTSLLSALVGVHSFQGTGWTVAGQLPQATGNHHPSVAPYGLYHCADGDLQIAVGSQNLWRALAEVTGLNADDPRYLTNADRVRNRDELERDLTALFSRESAQTWLERLSAAGIPAGRIRTLDEVYSCEQTRRPGLTVEVEHATLGCITLPGTPWRFDERPEPLHTPPPILGQHDFVVRAWLDLLDEPVRFAEEEGPATETAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4L0</accession>
    <name>W9E4L0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450098.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.186"/>
    <dbReference type="HOGENOM" id="CLU_031864_5_8_11"/>
    <dbReference type="OrthoDB" id="692968at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="29"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="552" mass="57057" checksum="5F062AB4FCE1C5C9" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4W2</accession>
    <name>W9E4W2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysophospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA70996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072027_0_0_11"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="110"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA70996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="335" mass="35375" checksum="18DC599AE7ED7539" modified="2014-05-14" version="1">MNPSPEKSTIVRSSAQARIDRIRPVFGALERAAPGLGSRWAWRLWCTPTRPSPAAVAKSRAAGTGEVLRLPVELPDWTGPRPVGRDGKTKPPLHAEIAVELLGPAGGPLVYLLHGWSGWRGQFAPIGRALAASGYRVVLIDAPSHGDSDPGTLGPGLSMPPDFTFALTAAVERFGPAHAVIGHSLGGGCVALALVEGLKAERVVFISPAADPIGFTRQLARMLGFGDRIRTRMLERGRRRIGLDAADFVVPPLAAGRTDLPPALIVHDRDDPTVPVAAGLSLAGSWRESRMIETAGLGHNRLLRDEAVIEAVVAFVDDPRATGPAGRKARSHVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4W4</accession>
    <name>W9E4W4_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nicotinamidase-like amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260297.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.22"/>
    <dbReference type="HOGENOM" id="CLU_068979_5_6_11"/>
    <dbReference type="OrthoDB" id="1442962at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="206" mass="22397" checksum="5E458F655D4EDF80" modified="2014-05-14" version="1">MTRALIVIDVQESFASRPLWRHTSNPDIVADVNQLVGHARAQGDLVVWVLHAKLGSGGPFDPESGLVRYQDGLEPLPGEPELRKTSHNAFTTTNLGQILTERGVRELVICGIQTEQCCESTARLAYDLGYSVTFVIDATATNPIAHRDLLAELGGEQPTVEQVLADPRTLGSDQILERVEYALAGRFARIATVAEVVTKKADAGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4W6</accession>
    <name>W9E4W6_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260305.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.27"/>
    <dbReference type="HOGENOM" id="CLU_097136_1_0_11"/>
    <dbReference type="OrthoDB" id="1920669at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="179" mass="20056" checksum="C30CAC949EFF8E84" modified="2014-05-14" version="1">MAKSTTEELVALLEYAHQRFDHRIDGLEEREYLWEPAPGCWSVREGDDGVERVDLEPGQPEPAPLTTIAWRLWHITDCLRSYTDRLFEDKDGGGREWTTSPAAATALVDSEWDRFVGHVKKLDQAGLERPIGPNFGPYADDSVHALVLHAADEVIHHAAEVALLRDLYQAAGGRALMNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4X1</accession>
    <name>W9E4X1_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260319.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.37"/>
    <dbReference type="HOGENOM" id="CLU_134343_0_0_11"/>
    <dbReference type="OrthoDB" id="1912908at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008497">
        <property type="entry name" value="DUF779"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05610">
        <property type="entry name" value="DUF779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009151">
        <property type="entry name" value="DUF779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="131" mass="14145" checksum="1322B82339F08E6D" modified="2014-05-14" version="1">MTMPQERSVSRVAVTDAAAALMRSLYQANGPLMFHQSGGCCDGSSPMCYLEGEFRTGGSDVLLARIEVPGVGEPVAFWMGAAQFERWRHTHLTVDVVPGRGSGFSLEAPEGVRFLIRSRLLTDAEEAALAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4Y0</accession>
    <name>W9E4Y0_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ActroDRAFT_0044</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 44927</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260327.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.47"/>
    <dbReference type="HOGENOM" id="CLU_047691_22_1_11"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="17"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="7">
        <location>
            <begin position="117"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ETA71026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="297" mass="31038" checksum="68060F14409335B9" modified="2014-05-14" version="1">MADTPTPTPTPTLTDAFERERGRLRAVALRMLGSHADAEDVVQEAWLRLSRQDAAEIGNLAGWLTIVVGRLSLDVLRTRQTHPVASSTEAEERMLIVLDEAPAPDEDAVLADAVGTALLVVLDSLAPSERLAFVLHDLFAVSFDEIGRIIGKSADAAKMTASRARRKVRAGGRVPPAAGAREQRAAVDAFLAAAREGDFEALLRVLDPAVKLDFETAEGKVVLLGATEVAAGARRAAGAASRGVAVYVDGLPGIAAFGPDGRVISVMAFTVEGGRIVGMHGVTDPARLAAVEVLGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4Y3</accession>
    <name>W9E4Y3_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleoside-diphosphate sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260336.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.54"/>
    <dbReference type="HOGENOM" id="CLU_007383_10_6_11"/>
    <dbReference type="OrthoDB" id="1616572at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="6"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="283" mass="30228" checksum="0C7EF7729CCB3A02" modified="2014-05-14" version="1">MILVTGATGNVGRELVRTLDAAGERIRILVRDPTRAAGLCDKTSVAVADLTQPTGLKAAFDGVDRLFLLTQGTGIDQAANAVAAAVAAGVRRIVLLSSVNVIGDPVPAMGRWHHARERLVLDSGIPATILRPSGFMTNALEWAPTIREGNYVLDPTGPGRFSLIDPADIADVAARALLEDGHEGEIYALTGDEVRTTAEHVRILADVLGRTIEVRTAATAEDAVRARYANGAPPALAAALLEAITAMRADTDGFRTDDVRQVLRRSPRTFEPWCVRHAEAFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4Y9</accession>
    <name>W9E4Y9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.71"/>
    <dbReference type="HOGENOM" id="CLU_023194_11_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="18"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="148"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="410" mass="45273" checksum="82A3F5956A206931" modified="2014-05-14" version="1">MSTSEIGTSPEMSTARELRVGVVGVGQRAVLAEYANRPGYSRVVSCADPTERGRADARRLFGPEARIHDDYQAMVGDDLDAVFVFTPDYVHTGPVLFFLEQGVAVFVEKPMAISIEDCDAMLAAAKAKGVRLYVGHNLRHLPTLRTMRRLIDEGAIGQVRAVWCRHFVGHGGDYYFKDWHAERDKTTGLLLQKGAHDIDVIHWLAGGYSREVVGLGALTVYGDNPHRRGAGEPPAAERMPEWFDRTAWPPARLRDLNPTIDVEDLTMMTARLDNGVYMSYQQCHYTPDYWRNYTVIGDAGRLENFGDGIEGDPAVVRVWNEYRSGYRAEADLTLQIEPDSEERHGGADLRLVAEFLRFVREGGPTEISPLAAREAVAAGVAATASLREGGRPVPVPALDPDLAAYFAGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4Z2</accession>
    <name>W9E4Z2_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein containing chitin-binding domain type 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ActroDRAFT_0072</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260363.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.76"/>
    <dbReference type="HOGENOM" id="CLU_041421_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021986">
        <property type="entry name" value="Spherulin4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040">
        <property type="entry name" value="PTHR35040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12138">
        <property type="entry name" value="Spherulin4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004919552" evidence="3">
        <location>
            <begin position="42"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="310"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ETA71051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="536" mass="55122" checksum="7B73421BD7C4A6CD" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4Z5</accession>
    <name>W9E4Z5_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ActroDRAFT_0082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260380.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.85"/>
    <dbReference type="HOGENOM" id="CLU_019399_1_1_11"/>
    <dbReference type="OrthoDB" id="1081028at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004921799" evidence="6">
        <location>
            <begin position="37"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="7">
        <location>
            <begin position="227"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="170"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ETA71061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="557" mass="55950" checksum="129031A546D4914A" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4Z7</accession>
    <name>W9E4Z7_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260386.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.90"/>
    <dbReference type="HOGENOM" id="CLU_069356_10_0_11"/>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041678">
        <property type="entry name" value="TetR_C_16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17920">
        <property type="entry name" value="TetR_C_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="211" mass="22743" checksum="1B30AD5A5A40A9D5" modified="2014-05-14" version="1">MNKSPGRGRRAGGPDTREQILETARRLFLANGYGGTTMRAVAAEADVDAALISYFFGSKRGLFGAALALTANPLEVARQELPGDLATLPERALTALLQAWDDPCTGEPLVAMLRGVVLDPGMGELVREAMHGELLAHLAERLGGVEGRRRAALFGAQMGGLIFTRYLLRLEPIASMNSDEIIRMYTPALRAVMFGPRPGRAVLARTTRTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>W9E4Z9</accession>
    <name>W9E4Z9_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding transcriptional activator of the SARP family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0093</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AfsR/DnrI/RedD regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004665_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15831">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="5"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="269" mass="29467" checksum="1892D0761F0720BF" modified="2014-05-14" version="1">MSVYAPAPADEAVQISVLGPLEVFDRGGERLLLRGPQTRTVFALLLLGAGTLVPTERLIEGVWGECPPPSAVLKVQGHICTLRKLLRPVRAAELLVTRPPGYRLQTEYYRCDLDEFTAAVRHAAALSAADDIEQACEVLDRALGCWRGPAFADISSEHVQRHVVRIHGLRSIAVQDRAWFELRLGRALRAIEQLGPEVDAYPLDERAREILIRAYLRLGQRHAALACYESGRSRLRDELGVSPGPALQRLAAVIRHGAASGLDPEGATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>W9E501</accession>
    <name>W9E501_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Redoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260394.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.102"/>
    <dbReference type="HOGENOM" id="CLU_124855_1_0_11"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="180" mass="19168" checksum="5C130BD97FC2FFE0" modified="2014-05-14" version="1">MHPLLIALAVFACAVSVLNLVLVLGVIRRLREHADRISRLSPEPPNPMLAVTERTDPFDAVTVEGDHVSRAALSGLTLVGVFSPSCPACEERLPRFLDFARSFPGGRDQTIAIVVGEPDEAADQVAVLSPIARVVVEDMEGSITKALKVRGFPAFGILDDSGTMVSAGTNTDWLRIPAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>W9E503</accession>
    <name>W9E503_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.107"/>
    <dbReference type="HOGENOM" id="CLU_2393266_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="93" mass="10266" checksum="AADDD2297CEA69C6" modified="2014-05-14" version="1">MCGVTSEDYDIWVLVDSERLHAPDPVLEPIGPTPFAGTGLGPLQIYSLFGPRRLHPPFDDGWMLLGFFRSSGALAQIHRLPASFDDEEARAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9E504</accession>
    <name>W9E504_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_887493_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="313" mass="34209" checksum="06A9083F2B6790F6" modified="2014-05-14" version="1">MGGAIALVGIALEFVGLGRTPLAAQDRVWHDIGLGFVVLGLAVPLRVWRRFERTRYSEALGAEAWKRIIWRAGVSPLLLGILGLLAGRALESEGAGAASHVVWVGALVCVALCPTVLLTGRVALRCAPRALRRSEITSEIVRELSAGNAFGVIPFNPDLGAAGRPDPLHERLPGPAVPSPRSVKIRKILGEECTLEWTGERLCVRRAHPVTGVARDLPREVAEMVCSASLDAGAPYFARDIGPRPVNRLRLLDAQGYVVVDFGVVLNDWEQFAALARRAGLLFRAYELRCEEKHDRKVDRLLFPRRGDVLEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>W9E506</accession>
    <name>W9E506_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ActroDRAFT_0113</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.118"/>
    <dbReference type="HOGENOM" id="CLU_069356_25_6_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16859">
        <property type="entry name" value="TetR_C_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="25"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ETA71091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="208" mass="22566" checksum="DC8BBEDBE5F1154C" modified="2014-05-14" version="1">MNRQRPAAEPASSSAQARSGRSRDSTIDERILTAARRQLSVLGFEGMSIASVAQEAGTTRQALYRRWADKAQLACDAVAAISEERGGSGAPQDPFDALVAELTDFQRGVSRPGRLSLVGTMLQETTGPEVLERYRATVIHPRRQRLAAVLRAAQQLGMIDADADLTVAVTMCTGNWYGRALAGEPIPEDWPRRTAALVWRALGGRPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>W9E508</accession>
    <name>W9E508_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1088337_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="255" mass="25662" checksum="872D1B9F64A1FC1B" modified="2014-05-14" version="1">MTAFETMFEKSLTSISAVETSRSARLARAAAGIEGVSRGTARVRAVAGDGLAVPEALAGLLPRGLERGGVLGVDQDRYLAASLVGSAVRSGGSAALVGVDDLGIEAVAAAGAPTSRLVVVRPDASSWVKALEVLIGAVEVVLVRPPAAVGDAVARRIVSRLRRGATVGTSLLVAGPAVFPAPVRLRVAAARWSGLEAGHGQLTARRATVVAEGRGLGGGSRAAEVYLPGPDGAAHPVRAAAPVDELAARRRLIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>W9E510</accession>
    <name>W9E510_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Integral membrane protein MviN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ActroDRAFT_0123</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">DSM 44927</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450085.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.129"/>
    <dbReference type="HOGENOM" id="CLU_006797_3_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13123">
        <property type="entry name" value="MATE_MurJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01695">
        <property type="entry name" value="murJ_mviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="500"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="603"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="627"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ETA71101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="672" mass="71121" checksum="E642C698B91B6532" modified="2014-05-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>W9E511</accession>
    <name>W9E511_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, tetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_063627904.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.134"/>
    <dbReference type="HOGENOM" id="CLU_069543_0_1_11"/>
    <dbReference type="OrthoDB" id="1570162at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="209" mass="22544" checksum="4B7FBD42209DBFAF" modified="2014-05-14" version="1">MEQIADAATAIADHDGLDAVTMQVVAERLGAAKMALYRYLPGRAELEAVMLDRALGAPDTFGDGEWASALTRWATALYERASQRPWTVELIQRPHLPGPNELGWYEAGLAALQELNLDGREKLDVLAMLAGHVVSIVRQQAAGPAPEEDLAKALAPVLMRNAHAFPLTVAAFSQPSGSEHDDALHFGLARMVAGIEALATARAHPQRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9E514</accession>
    <name>W9E514_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260432.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.142"/>
    <dbReference type="HOGENOM" id="CLU_833230_0_0_11"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="333" mass="35773" checksum="079CC9D19C6CC22F" modified="2014-05-14" version="1">MFGQTVWERNLHQAGSARGLAATAKDIVVHERATRLVGLDPHDGAQRWDIPCGTWPRATIIAGDRCLVIPQSPDQLSCLDVRTGDVLWSAQLARFTGHLAATRDTVLVGGWRGSTPLTAFDLQTGSLLWQSPKRVKIEAPVVVDSGILVGESHSSEISLIEPRDGSVKAQWSLPEPLASSDNHPVLTPLDGDRVLARCGPRTVVEFSLSTGTVATFFRSDDVDLAPQAVGRTGSILWVLPVCGSHAVRTLHTHDGTPLRRFAAADVDHAVQAGSGFVVADFTGRLALVDPDPAAPRYSTHSARIAQRIRVLRDHGPGTVLVMTKGTLRVVEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>W9E517</accession>
    <name>W9E517_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_051450090.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1754944_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="148" mass="16275" checksum="A71504BB5C3D3D30" modified="2014-05-14" version="1">MNLPPYLSPEDEQSAASTTASGAMAIVTTPAGIVLHLRDDKPEIPHPACWSLFGGATDDGELPDQTIRRELREELALDEVNLRPLWRVVDLDGDGRQLTIFEARTHRHARELTLAEGQALGVFDLASALELRLADFCRRSLLSYAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>W9E525</accession>
    <name>W9E525_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger protein, UBP type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ActroDRAFT_0177</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260478.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166099_0_0_11"/>
    <dbReference type="OrthoDB" id="1674309at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBP-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ETA71151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="116" mass="12441" checksum="FA84AF2491A67F5C" modified="2014-05-14" version="1">MNAQQGIDPSVAPSGTGCVECDDAGGWWVHLRRCAQCGHIGCCDDSPSKHATAHAKATGHQLIRSFEPGEEWFWNYRTSEAYDSGPALAPPENHPLDQPVPGPAGHVPANWQEVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>W9E527</accession>
    <name>W9E527_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ActroDRAFT_0188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_034260494.1">
        <property type="nucleotide sequence ID" value="NZ_KI632511.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1631845_0_0_11"/>
    <dbReference type="OrthoDB" id="1913026at2"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ETA71161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="162" mass="17381" checksum="169CA9468DA85DD3" modified="2014-05-14" version="1">MTFNVATTVWHSIPLIPYGAILHVPEGWEAMPPQPANGPEIMRAAGGAGRNLIVFKLPAGGRTADEVADVAQGKLEAHGYGDFTRAAVPFAGQPGVALDFVTRTGNGEEVYRTREYFAVRGNAGYVLGMGSRTWEEHLPLIEAIAARFTLIDQAAYGEDAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>W9E528</accession>
    <name>W9E528_9ACTN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endo/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_879660_0_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="311" mass="32379" checksum="8842591FA52A53B8" modified="2014-05-14" version="1">MAAAPAASADTTTTATYTVWQWNVSGNVMNAGSTSDGMVSAAVSSILNRDADFVSFNEICYSQYKAIQADLAGTWTTAASFSRFAASEAPKAGLCGSTTDDTDNSFGIALFSKQALGTSSQYTLPSDGSPEDRKMLCAPLAAQPDMVFCTVHITTSPDLTDGVANNVRQLEYVRSTLDGFDAAGETYIIAGDFNAQPNYGRLNDFYDSSIDTVANPNNTGSNFELDDTDTRCPGYGEATAAPGSKEATPPCGGNAKIDEIFVRSTRVAPNTSYSADALAIPVTCTSSANPGTLVACSDHNVLTGTVTVTIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-05-14" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>W9E530</accession>
    <name>W9E530_9ACTN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ActroDRAFT_0202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Actinospica robiniae DSM 44927</name>
        <dbReference type="NCBI Taxonomy" id="479430"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Catenulisporales</taxon>
            <taxon>Actinospicaceae</taxon>
            <taxon>Actinospica</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2013-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Eisen J."/>
                <person name="Huntemann M."/>
                <person name="Han J."/>
                <person name="Chen A."/>
                <person name="Kyrpides N."/>
                <person name="Mavromatis K."/>
                <person name="Markowitz V."/>
                <person name="Palaniappan K."/>
                <person name="Ivanova N."/>
                <person name="Schaumberg A."/>
                <person name="Pati A."/>
                <person name="Liolios K."/>
                <person name="Nordberg H.P."/>
                <person name="Cantor M.N."/>
                <person name="Hua S.X."/>
                <person name="Woyke T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">DSM 44927</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="AZAN01000001">
        <property type="protein sequence ID" value="ETA71171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|479430.3.peg.210"/>
    <dbReference type="HOGENOM" id="CLU_027402_4_0_11"/>
    <dbReference type="Proteomes" id="UP000019485">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13333">
        <property type="entry name" value="rve_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="135"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ETA71171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000019485"/>
        </source>
    </evidence>
    <sequence length="306" mass="34832" checksum="549B68E77F28F289" modified="2014-05-14" version="1">MRFAFISSAVEEQKESGIPRRYRYPIELMCRILAVSRSGYYAWSNRQACAHAQRDAELTAAIVAIDRAHEGRYGIDRIHAELAKQGHATSQRRVRRLARAAGLRCVHPAAKRTTTTTQDPANSRGLVDLVERDFFPDTPNEIWYGDVTYIWTMTGWCYLATVIDGFSRQVIGWAVAEHMREQLVLDALRMAIARRRPHRGQTVMHTDRGSVYTGRAFRDLCLDQGILPSVGKTGICFDNAAAESFNALYKKELIHLSVWVDCKAVRAASFEYIETYYNRTRIQRQLGYLSPAQYESIFDNKLSLAA</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>