<?xml version="1.0" encoding="UTF-8"?>
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<entry dataset="TrEMBL" created="2011-06-28" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>B9A0T5</accession>
    <name>B9A0T5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <organism evidence="2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2">
        <name>EcOYM</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2002" name="Microbiology" volume="148" first="1389" last="1396">
            <title>Evidence of intermolecular recombination between extrachromosomal DNAs in phytoplasma: a trigger for the biological diversity of phytoplasma?</title>
            <authorList>
                <person name="Nishigawa H."/>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Jung H.Y."/>
                <person name="Kuboyama T."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="11988512"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
            <plasmid evidence="2">EcOYM</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
            <plasmid evidence="2">EcOYM</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB076263">
        <property type="protein sequence ID" value="BAH22135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002600755.1">
        <property type="nucleotide sequence ID" value="NC_012089.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959589.1">
        <property type="nucleotide sequence ID" value="NC_019167.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959595.1">
        <property type="nucleotide sequence ID" value="NC_019168.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959601.1">
        <property type="nucleotide sequence ID" value="NC_019169.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_214983.1">
        <property type="nucleotide sequence ID" value="NC_006903.1"/>
    </dbReference>
    <dbReference type="OMA" id="YQIQYIH"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Plasmid EcOYM"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAH22135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="154" mass="17604" checksum="1704E4E59F72F863" modified="2011-06-28" version="1">MNKKRKIILIMWTIFIAIILLILLFLLGLRLPKFIKSNQPKTENQAKTQSQYQIQYIHDTNKINNIIKSLIKLKQLKESKKQKQQLKPQTEKQEQEQEQYQFDWNSNYDNDDNKLVKDIAVVTLATGAAVISCVVLAPIFASVGPIAAPLALLA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-15" modified="2022-08-03" version="108" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPH3</accession>
    <name>SYN_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Asparagine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Asparaginyl-tRNA synthetase</fullName>
            <shortName evidence="1">AsnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">asnS</name>
        <name type="ordered locus">PAM_754</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPH3"/>
    <dbReference type="SMR" id="Q6YPH3"/>
    <dbReference type="STRING" id="262768.PAM_754"/>
    <dbReference type="PRIDE" id="Q6YPH3"/>
    <dbReference type="EnsemblBacteria" id="BAD04839">
        <property type="protein sequence ID" value="BAD04839"/>
        <property type="gene ID" value="PAM_754"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_754"/>
    <dbReference type="eggNOG" id="COG0017">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004553_2_0_14"/>
    <dbReference type="OMA" id="DNMDLAE"/>
    <dbReference type="OrthoDB" id="1138123at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-908-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000176436" description="Asparagine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00534"/>
        </source>
    </evidence>
    <sequence length="506" mass="58286" checksum="07E58F4F1E2A0F0C" modified="2004-07-05" version="1">MKISIKDIFQKPELFYQKKIVLNGWVRNCRYQKKLIFIDLNDGTFLENLQIICKETKTKNIETAAEITEFHENQKVNTKNESPNNINLEKLKEMLQIGASLQVEGILKATNNPQTPFEISAQNVSLLGASDFSYPLQPKKHSKAFLRQISHLRVRTKLFGAVFRIRNTAFFALHSFFQKKGFFHINTPIITANDGEGAGELFQLTTLNLEALPQTKNIPNASKLADETISKNEIDYQKDFFGKKVFLTATGQLEAEAMALGLNKVYTFGPTFRAEKSNTPRHAAEFWMLEPEMAFCNLSQNLKVAQEMLQFVIAKCLEQNYQDIEFLDKTEKNCLIEELKNISEEKEFLTVKYEQALEILQKSNTKFENPLFYGADLATEHEKYLTETHFKKPVFIVDWPKEIKAFYMKNNPDQKTVAAMDLLVPRVGELIGGSQREENLSVLIEKMNQMKIPQKDLEWYLDLRRFGGCIHSGFGLGFERLLIFLTGLDNIRDVIAFPRTYHNLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="117" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPI2</accession>
    <name>Q6YPI2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">thrS</name>
        <name evidence="9" type="ordered locus">PAM_745</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="2"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_745"/>
    <dbReference type="EnsemblBacteria" id="BAD04830">
        <property type="protein sequence ID" value="BAD04830"/>
        <property type="gene ID" value="PAM_745"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_745"/>
    <dbReference type="eggNOG" id="COG0441">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008554_2_1_14"/>
    <dbReference type="OMA" id="QIDFHQP"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="20"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="308" mass="35865" checksum="CF8F11510C48D155" modified="2004-07-05" version="1">MFNKEVGLGLPFWLPKGATVRRIVERYIVDKELSYDYHHVYTPIMANTELYRISGHLDHYASNMFPIMTLENGEKLVLRPMNCPHHMMIYKKTPHSYKELPLRIAELGMMHRFEKSGAVSGLQRVREMTLNDAHIFACPDQIKEEMKKIINLILEVYRDFNIKNYELRLSYRDPNDTEKYFNDDQMWHHAEKTLKETIQELSLPFKEAIGEAAFYGPKLDVQVFTALGNEETLSTVQLDFLLPQKFDLTFIGEDNKHHRPVVIHRAVVSTMERFLAHLVEETKGVFPLWFAPVQVLLIPVSAPSTFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPI3</accession>
    <name>Q6YPI3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translation initiation factor IF3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">infC</name>
        <name evidence="6" type="ordered locus">PAM_744</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IF-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_744"/>
    <dbReference type="EnsemblBacteria" id="BAD04829">
        <property type="protein sequence ID" value="BAD04829"/>
        <property type="gene ID" value="PAM_744"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_744"/>
    <dbReference type="eggNOG" id="COG0290">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054919_3_2_14"/>
    <dbReference type="OMA" id="RNMIMFL"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="5">
        <location>
            <begin position="5"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="4">
        <location>
            <begin position="65"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="150" mass="17378" checksum="C51605DAB2637EAF" modified="2004-07-05" version="1">MKKANQLGVFDQKEALKLSEQKEIDIVVVNADASPMVARLMNYQKHRYNQQKKLREAKKKTQIIVLKEIRLNPTIDKNDLNTKIKQAQKFLKQGDKVKVSMRFRGRMINNFQLGETVFKQVMQDLKNLSQIETPLKLQGNQLTAVLSPLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-01" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPI8</accession>
    <name>ACP_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acyl carrier protein</fullName>
            <shortName evidence="1">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">acpP</name>
        <name type="ordered locus">PAM_739</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPI8"/>
    <dbReference type="SMR" id="Q6YPI8"/>
    <dbReference type="STRING" id="262768.PAM_739"/>
    <dbReference type="EnsemblBacteria" id="BAD04824">
        <property type="protein sequence ID" value="BAD04824"/>
        <property type="gene ID" value="PAM_739"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_739"/>
    <dbReference type="eggNOG" id="COG0236">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108696_5_2_14"/>
    <dbReference type="OMA" id="CEIPDEQ"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-894-MON"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword id="KW-0276">Fatty acid metabolism</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0596">Phosphopantetheine</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000180160" description="Acyl carrier protein">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="2">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <sequence length="76" mass="8598" checksum="CBF844F37AAC88C5" modified="2004-07-05" version="1">MVFEKIKALIATQLSLDASTITLDTRFKEDLGLDSLDALELVMEVEKTFQINISDATLQNFKTVQDIVFYITKNTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPK1</accession>
    <name>Q6YPK1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_724</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_724"/>
    <dbReference type="EnsemblBacteria" id="BAD04809">
        <property type="protein sequence ID" value="BAD04809"/>
        <property type="gene ID" value="PAM_724"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_724"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2718390_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="72" mass="8121" checksum="0380EF8AE391F562" modified="2004-07-05" version="1">MKVKNQAMLITYADSLGKNLDDLKFVLKEDIKDVVGGIHLLPFFLQQAIGGFHQSNTTKLILFLEIGKIFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="112" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPL1</accession>
    <name>Q6YPL1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Superfamily II DNA and RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">srmB</name>
        <name evidence="9" type="ordered locus">PAM_714</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_714"/>
    <dbReference type="EnsemblBacteria" id="BAD04799">
        <property type="protein sequence ID" value="BAD04799"/>
        <property type="gene ID" value="PAM_714"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_714"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_21_1_14"/>
    <dbReference type="OMA" id="FGCQALV"/>
    <dbReference type="OrthoDB" id="626183at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-869-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="8">
        <location>
            <begin position="3"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="34"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="231"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="3"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="552" mass="63072" checksum="89BEE78DB6207120" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPL9</accession>
    <name>HRCA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heat-inducible transcription repressor HrcA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hrcA</name>
        <name type="ordered locus">PAM_706</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HrcA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPL9"/>
    <dbReference type="SMR" id="Q6YPL9"/>
    <dbReference type="STRING" id="262768.PAM_706"/>
    <dbReference type="EnsemblBacteria" id="BAD04791">
        <property type="protein sequence ID" value="BAD04791"/>
        <property type="gene ID" value="PAM_706"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_706"/>
    <dbReference type="eggNOG" id="COG1420">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050019_1_0_14"/>
    <dbReference type="OMA" id="DYPGTMG"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-859-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00081">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002571">
        <property type="entry name" value="HrcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021153">
        <property type="entry name" value="HrcA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023120">
        <property type="entry name" value="WHTH_transcript_rep_HrcA_IDD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34824">
        <property type="entry name" value="PTHR34824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01628">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005485">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00331">
        <property type="entry name" value="hrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_0000182517" description="Heat-inducible transcription repressor HrcA">
        <location>
            <begin position="1"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00081"/>
        </source>
    </evidence>
    <sequence length="342" mass="39018" checksum="03AF9F7E93E306D1" modified="2004-07-05" version="1">MMNMLSDRKKLILKAVVENYSQKGQPVGSKLLTHLPYLKFASATIRYDMVQLEKEGFLQKNHTSSGRVPSFKGYTYYLNHLLTRDHDVACMFESIDKVIQKKRFCKGQVIKEALSLLNNLTNYTAMAIGSDIFNNSKINKIDFIPLNSTQAVILIITDKGNVQHQNISLDQTKEISIYDLKDVVQVVNDLLTDKFLSEAANIIQSDFFKQTIAKYICFQEQLIALFMEVFSSFASENLYFSGVSKMLEKPELSNPEIIKKFMGLLERKELLKIMLNQDSLSFKFSDGLQLTPLKDCMILSIPFDVNPNEKGRIAVVGPSWMKYPKVIPILEYLAVHLSKLND</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-03-07" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPM1</accession>
    <name>DNAK_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dnaK</name>
        <name type="ordered locus">PAM_704</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="1">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="sequence caution" evidence="3">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04789" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04789.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPM1"/>
    <dbReference type="SMR" id="Q6YPM1"/>
    <dbReference type="STRING" id="262768.PAM_704"/>
    <dbReference type="EnsemblBacteria" id="BAD04789">
        <property type="protein sequence ID" value="BAD04789"/>
        <property type="gene ID" value="PAM_704"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_704"/>
    <dbReference type="eggNOG" id="COG0443">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005965_2_4_14"/>
    <dbReference type="OMA" id="ISIKRHM"/>
    <dbReference type="OrthoDB" id="161217at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-857-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <feature type="chain" id="PRO_0000225988" description="Chaperone protein DnaK">
        <location>
            <begin position="1"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="567"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="594"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="1">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="615" mass="66958" checksum="5D3E814EE4073CD2" modified="2006-03-07" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPM9</accession>
    <name>Q6YPM9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">PAM_696</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_696"/>
    <dbReference type="EnsemblBacteria" id="BAD04781">
        <property type="protein sequence ID" value="BAD04781"/>
        <property type="gene ID" value="PAM_696"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_696"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1914935_0_0_14"/>
    <dbReference type="OMA" id="TNQNIPP"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="102"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="132" mass="15298" checksum="5448E6D240D658D3" modified="2004-07-05" version="1">MKTLTKIYLSFLSIFGLILFVLLIVGLTKPQTTPNTNQNIPPNTHTHHHEEAKQNNKELNPKEKEALSEIQTRLKELELFNQKNIEKSKKIKEEDNILSQQINSNLAKINTLNQEINTLKNQLEEKTNQLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPN2</accession>
    <name>Q6YPN2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome segregation ATPase homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">smc</name>
        <name evidence="2" type="ordered locus">PAM_693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_693"/>
    <dbReference type="EnsemblBacteria" id="BAD04778">
        <property type="protein sequence ID" value="BAD04778"/>
        <property type="gene ID" value="PAM_693"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_693"/>
    <dbReference type="eggNOG" id="COG0497">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1007742_0_0_14"/>
    <dbReference type="OMA" id="TEQLEYK"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="276" mass="32834" checksum="6BEE2064AD1CFE10" modified="2004-07-05" version="1">MNPKKMNPKKEKLKKKQTAKPPELNNNEQTPQLTTQQPIHKQKIENKRNELNPEMQKQVEELIQQEKAKTQQLEQEKNYLEANLQAQQLEMLNIKNQKDNLENQLTSKEKELANNQELTEETKNKLQQEINDIQTNLNHQIENTQNKNNEIQNLQTQKTQLENQLFSNKQDLEKLQQEINQKEEQLHTKQQQLISQINLSNEEKQQLNSEINTLKTDINQEKVNFEAQLALKEEEITQLKQNETNLKQQLTQKQDETTRLREQTRKNFGRNSKTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPN4</accession>
    <name>Q6YPN4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_691"/>
    <dbReference type="EnsemblBacteria" id="BAD04776">
        <property type="protein sequence ID" value="BAD04776"/>
        <property type="gene ID" value="PAM_691"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_691"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068887_0_0_14"/>
    <dbReference type="OMA" id="PLWIWFI"/>
    <dbReference type="OrthoDB" id="1558360at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-842-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="265" mass="31134" checksum="2D5B9693D28909BD" modified="2004-07-05" version="1">MELFKILTIVFFLGIIFGSIPLWIWFIQKRENTNRIKKVNIKTGLIIYYVMMSVSVVGFGVFLFLDNKYDIIKSKPKIYEIPSTKIETQEEWFQTKSGAKYTYNENNLQKNNNKSWLLTDIAQEGVPMIKKTYTFYGLNGLGRGHHREHEPADLALFVKNPFDKWYDEGMRVDEFDGFHTKYKDKNSQFDGGNGVSINPLNHTIYINYKGPKHLLEEDKDFFMDEVNCTSNERSPEGVLKSKTYYLHFNPKQAYITLYTQKHNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPN6</accession>
    <name>Q6YPN6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_689</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_689"/>
    <dbReference type="EnsemblBacteria" id="BAD04774">
        <property type="protein sequence ID" value="BAD04774"/>
        <property type="gene ID" value="PAM_689"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_689"/>
    <dbReference type="HOGENOM" id="CLU_2247279_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="104" mass="12607" checksum="A01A4AC835466156" modified="2004-07-05" version="1">MLMNSTPLTILERLFFKQRSPINYWAQVQCQLYCSQAKFAYFLIYFNDTNYHVVRIYQDNNFINKMIKDSKKYLELLHNTKKRIITNNLFKTINQTKSQIRPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPQ2</accession>
    <name>Q6YPQ2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replication initiation/membrane attachment</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dnaB</name>
        <name evidence="2" type="ordered locus">PAM_673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_673"/>
    <dbReference type="EnsemblBacteria" id="BAD04758">
        <property type="protein sequence ID" value="BAD04758"/>
        <property type="gene ID" value="PAM_673"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_673"/>
    <dbReference type="eggNOG" id="COG3611">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040783_0_0_14"/>
    <dbReference type="OMA" id="TQERIYW"/>
    <dbReference type="OrthoDB" id="729506at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-822-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034829">
        <property type="entry name" value="DnaD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006343">
        <property type="entry name" value="DnaD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07261">
        <property type="entry name" value="DnaB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DnaB_2" evidence="1">
        <location>
            <begin position="300"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="397" mass="46601" checksum="B662EB23B202D892" modified="2004-07-05" version="1">MLSHLNLFQIKNSVFLSLEDHQSLSLLYQPLIGTHSLGIYHILATLKPNIFYQHQFLFDLSVVSKNDFLEAQEKLEALNLLQTFCNSETQERIYWLNLPCRSEEFFKDPLFSNFLLSEVGEATFLSLQNHFSKEASTKKNNWDAFQDISKKFDDLFQVQKMDLPTDFTCPNNQTNSSPRQFLNNAFDYKLFLQKLPQRFKKPSLTCNQTSDFIQKLSLVYNLDEATLSEIYQKTFPKPSEIELSKLSLGVKRYYQMHTQNQNLVFAKKTQDNEQDTIALLKRKDSTQRIIINHCPKNMQATAADTVFQFMERNNLEPGLVNVLLTYILERKGFVPSVVYLEKILKSWEQKGIFDTETAYDFYMEQEKNQSQTKFRSNLKKPQISPKWLEDFKKKKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="110" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPQ4</accession>
    <name>Q6YPQ4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cspC</name>
        <name evidence="4" type="ordered locus">PAM_671</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_671"/>
    <dbReference type="EnsemblBacteria" id="BAD04756">
        <property type="protein sequence ID" value="BAD04756"/>
        <property type="gene ID" value="PAM_671"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_671"/>
    <dbReference type="eggNOG" id="COG1278">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117621_6_3_14"/>
    <dbReference type="OMA" id="HYSTIKM"/>
    <dbReference type="OrthoDB" id="2034748at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-819-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="5"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="74" mass="8403" checksum="3881EECE9F892524" modified="2004-07-05" version="1">MQDKKQQGTCRWFSKDKGYGFIVSVDGKDIFVHYSSIQTEVFGRKTLNENDKVEFTVKEGDRGAQAVDVVVVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPQ8</accession>
    <name>Q6YPQ8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent protease Clp, ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">clpX</name>
        <name evidence="3" type="ordered locus">PAM_667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gram-positive plasmids replication protein type 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_667"/>
    <dbReference type="EnsemblBacteria" id="BAD04752">
        <property type="protein sequence ID" value="BAD04752"/>
        <property type="gene ID" value="PAM_667"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_667"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_722892_0_0_14"/>
    <dbReference type="OMA" id="KSGRYGY"/>
    <dbReference type="OrthoDB" id="158352at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-813-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005727">
        <property type="term" value="C:extrachromosomal circular DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003916">
        <property type="term" value="F:DNA topoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000605">
        <property type="entry name" value="Helicase_SF3_ssDNA/RNA_vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002631">
        <property type="entry name" value="Plasmid_rep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01719">
        <property type="entry name" value="Rep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00910">
        <property type="entry name" value="RNA_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="196"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="376" mass="44281" checksum="2595D468AB56E733" modified="2004-07-05" version="1">MKLRICELVINSNLINQSKIENILEAKKNAIQNYAFILHDKDIYQNEKEAQLNGKKIGDLKTPHWHIYLRFNNAYDVKHIAQWFNTEENFVSKIKGRFSDALMYMIHANRTDKHQYDEREVVSDFDWKSEAQQDIFLRKYKIDTRLKDILTKIHSGEIKEYNITNYISIIEHNIYSAAIEKAFKYRTNTLKGIERNMECVFITGMSGSGKTTLAKKIAKDKNYQTYISSGSNDVLDDYQGQECIILDDLRSNCLGLTDLLKMLDNNTSYSVKSRYKNKVLECKLIIITTVKSIDDFFEDIFKKDESIIQLKRRCKLHISLDSKYISYSMWNPVKMEYEKPFKKPNNLLNKFQIKALSEKEQKEFIKKITNIDLDED</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-05-01" modified="2022-08-03" version="131" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPR6</accession>
    <name>POTA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="1">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">potA</name>
        <name type="ordered locus">PAM_659</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + polyamine-[polyamine-binding protein]Side 1 = ADP + phosphate + polyamineSide 2 + [polyamine-binding protein]Side 1.</text>
            <dbReference type="EC" id="7.6.2.11"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPR6"/>
    <dbReference type="SMR" id="Q6YPR6"/>
    <dbReference type="STRING" id="262768.PAM_659"/>
    <dbReference type="EnsemblBacteria" id="BAD04744">
        <property type="protein sequence ID" value="BAD04744"/>
        <property type="gene ID" value="PAM_659"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_659"/>
    <dbReference type="eggNOG" id="COG3839">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_14"/>
    <dbReference type="OMA" id="IHVMRFN"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-804-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015417">
        <property type="term" value="F:ABC-type polyamine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51305">
        <property type="entry name" value="POTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000286269" description="Spermidine/putrescine import ATP-binding protein PotA">
        <location>
            <begin position="1"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="5"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Insert">
        <location>
            <begin position="105"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01726"/>
        </source>
    </evidence>
    <sequence length="417" mass="47836" checksum="80EC96EA39C581AB" modified="2004-07-05" version="1">MKTLIILKDLTKVFDNQLILRGINLEIKQNEFVTLLGPSGCGKTTILRILGGFENPSSGEVLFQEKSILNVAAHKRPINTVFQKYALFPHLNVFENVAFGLRLKDFNSKIKANLSLNKTHYQTNKANLSKTFHQELTKDLTQEKTTQITHNFNNQIETLTKDFETKQTALKCKKINKKEQEEQIQKEVLKYLKIMGLQGLEKRTIEQLSGGQQQRVAIARALINKPQVLLLDEPLSNLDLKLKQEMQYELKEIQKNSGITFLFVTHDQEEAFTMSDKVVVMNHGEIQQIGSPEDIYNEPANRFVAQFVGESNLIKGVMKDDFLVHFDNQTFNCVDKGFRKEENVDIVIRPEDIDIVSQGKGLITGIVQSIIFKGVHWEIDVKTAQRTYTIHTTDHVELNKQVDITFNPEDIHVMEIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPR9</accession>
    <name>Q6YPR9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase specialized sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fliA</name>
        <name evidence="2" type="ordered locus">PAM_656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_656"/>
    <dbReference type="EnsemblBacteria" id="BAD04741">
        <property type="protein sequence ID" value="BAD04741"/>
        <property type="gene ID" value="PAM_656"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_656"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110732_0_0_14"/>
    <dbReference type="OrthoDB" id="1702475at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-801-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="200" mass="23822" checksum="BFAF66248AC0A9B4" modified="2004-07-05" version="1">MLRKELFKVFLKNKKNLEIRNQLITLHLPLVKKIVNQFKYYPRVLTKEDLYREGILGLIKALNHYQDLGYDFIAYATPTIKSEINELIRKSHSPSIPQKNHKKDNLSFREEFYEPYQINKLNPHQLWLKQVNHEIFLKKMKVKLSKTEFKIIHLSFGVPLGNINEDYQKCYTNTEIAEKLNLSLKQVENIKNIAIKKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPS0</accession>
    <name>Q6YPS0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_655</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_655"/>
    <dbReference type="EnsemblBacteria" id="BAD04740">
        <property type="protein sequence ID" value="BAD04740"/>
        <property type="gene ID" value="PAM_655"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_655"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-800-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="114" mass="13365" checksum="F74DB03EE9D5A705" modified="2004-07-05" version="1">MLNKVQLIGRLSHDLEKQYINSNNEQIPKIDFQLAVNLKEITQFIPCVVFRKQADNMKKYLHKGSKIYLEGILSIQKYMNNEGQTKINTKVILQNVIFFDNKPLDNKPQENLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPS5</accession>
    <name>Q6YPS5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_650"/>
    <dbReference type="EnsemblBacteria" id="BAD04735">
        <property type="protein sequence ID" value="BAD04735"/>
        <property type="gene ID" value="PAM_650"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_650"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1137139_0_0_14"/>
    <dbReference type="OMA" id="QETKFEN"/>
    <dbReference type="OrthoDB" id="1779749at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-793-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="231" mass="27584" checksum="E9F7A0FD50501784" modified="2004-07-05" version="1">MFNIKKIIKWFFIILGILLFLLIGFFVLTEMEIIKLPKEEIPILKETAFENIEEWYDDKQKCTMIKAKYTFDGLNGIGYYQQQLANKENIGAFELMKIQERLELQKEPSNLVCYIKDRHPFDRWNKDGDTYNFTTLDGFDSASFDKKDDSQLYLYVKFEKQQHKGPGFNHLILKYKGPKHFLEEDKDYYLGRARVDDSNFESTNFHLHFNPVRKTLSLYQDKHNNDKTQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPT0</accession>
    <name>Q6YPT0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Replicative DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dnaB</name>
        <name evidence="2" type="ordered locus">PAM_388</name>
        <name evidence="3" type="ordered locus">PAM_645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_388"/>
    <dbReference type="EnsemblBacteria" id="BAD04473">
        <property type="protein sequence ID" value="BAD04473"/>
        <property type="gene ID" value="PAM_388"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04730">
        <property type="protein sequence ID" value="BAD04730"/>
        <property type="gene ID" value="PAM_645"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_388"/>
    <dbReference type="KEGG" id="poy:PAM_645"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_546093_0_0_14"/>
    <dbReference type="OrthoDB" id="497256at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-464-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-785-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="1">
        <location>
            <begin position="190"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="497" mass="58419" checksum="FDC091833276507F" modified="2004-07-05" version="1">MLTNEQKALKQIISYMNQNKAEQLNFYFQLIDPQSFLDKQHTKIFQALKYLTLNQKNTHPFDKIKSQTEIIKELLTYLQTHFPQDHFTKASLSFLSDDVNEENHLNFLDNLKHTYTQEKLFQQLLKIISPSFENKDPYHKHLYYQEIFDKLRKFMAFLPHQSDQTLCTLKQMSSIHPEFFAADQQSKQKIQEEYHRLSETFRGLNQATKGFKKGQIITIGGYTGLGKTTFVYNLLLDITKTKHQETHHHPHLLVFSYEMTMEENLSRLLAHQTQIPLDVILDKNLEDLNITTHTYMERMNKAQKLFFQLNLSFSYDQGKNIDYVIDLVYRLHLEKQAEIIVIDHLQITKSSNHLENDRLAIDEIMTKLKQLAMELNIVIIILSQFSRDTYSHYQGKSPEITALKGSGGIETNSDIVLMMSEFQPKLSKDQEKPLNIYNQNCNQLYLASKNNESQKIIELSIKKNRSGTKKNLVYHFEMTTQTFQEIGYILPYSLESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPT2</accession>
    <name>Q6YPT2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_643</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04728">
        <property type="protein sequence ID" value="BAD04728"/>
        <property type="gene ID" value="PAM_643"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_643"/>
    <dbReference type="HOGENOM" id="CLU_1979285_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="126" mass="15330" checksum="004BB2110B03917C" modified="2004-07-05" version="1">MIISLLLIYKLLLSDLTPLKRQNNPLKHLFNIFQINYKNESKNIIKKLIGKINLHKLENLQLYQLDPQKLDKYHKPIKTNYKKGLNIIYYRQEDLKYIQSFLTKDKQGYRVKKLHPKYKYIPKQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPT4</accession>
    <name>Q6YPT4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amino acid transporter, amino acid-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mdoB</name>
        <name evidence="3" type="ordered locus">PAM_641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_641"/>
    <dbReference type="EnsemblBacteria" id="BAD04726">
        <property type="protein sequence ID" value="BAD04726"/>
        <property type="gene ID" value="PAM_641"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_641"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2001524_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-781-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="2"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="124" mass="13998" checksum="AE89A9B571897C60" modified="2004-07-05" version="1">MLLKEIAKQQGKELELTINTFAVLLGDIETGKADITASCLAITEDRKAKVDFSIAYNVPMNGFVVRRDNKDFESNLFAHNARVKDKDLFDHLDNLYENAKKEGKEKSFTFIAVTASATDTDFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPT6</accession>
    <name>Q6YPT6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type amino acid transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">artM</name>
        <name evidence="7" type="ordered locus">PAM_639</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_639"/>
    <dbReference type="EnsemblBacteria" id="BAD04724">
        <property type="protein sequence ID" value="BAD04724"/>
        <property type="gene ID" value="PAM_639"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_639"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_1_14"/>
    <dbReference type="OMA" id="IWTFVWI"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="24"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="252" mass="28563" checksum="92F8D3CF70D11D5B" modified="2004-07-05" version="1">MRNIKNLGLWQKMCYNFPSYKKGLYNTLLISIDGLLIGFLLALFLVGTKTKVTNTRTNNTFVKACYKMISKCVDTYIWLLKGVPIAAQAMLVWFSNSLWWPSKGLMPDLFPQINQIHAALFVITLNAGASLTMILMQNIKFVDKGQIEAAFSLGMTQRQTFYNIIFPQALKKSVPFVITQFITNIKDCTFFAFIGLVEMGWIANRNMGITADVITPFVLLSIIYLVLIQCNNTLAKYLEKKLNPSFRPVISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="131" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPU8</accession>
    <name>Q6YPU8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 17" type="primary">dnaG</name>
        <name evidence="17" type="ordered locus">PAM_627</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13 14">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="domain">
        <text evidence="12">Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_627"/>
    <dbReference type="EnsemblBacteria" id="BAD04712">
        <property type="protein sequence ID" value="BAD04712"/>
        <property type="gene ID" value="PAM_627"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_627"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013501_3_3_14"/>
    <dbReference type="OMA" id="ATITCIK"/>
    <dbReference type="OrthoDB" id="1071997at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-763-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="16">
        <location>
            <begin position="250"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CHC2-type" evidence="12 14">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="545"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002811-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="BAD04712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="604" mass="70660" checksum="77D4DA70E62CDFAD" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPW1</accession>
    <name>Q6YPW1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNAP delta factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">PAM_614</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RpoE family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_614"/>
    <dbReference type="EnsemblBacteria" id="BAD04699">
        <property type="protein sequence ID" value="BAD04699"/>
        <property type="gene ID" value="PAM_614"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_614"/>
    <dbReference type="eggNOG" id="COG3343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1485973_0_0_14"/>
    <dbReference type="OMA" id="WDKDFFE"/>
    <dbReference type="OrthoDB" id="1688967at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-740-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007759">
        <property type="entry name" value="Asxl_HARE-HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038087">
        <property type="entry name" value="RNAP_delta_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029757">
        <property type="entry name" value="RpoE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04567">
        <property type="entry name" value="RNAP_delt_lowGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51913">
        <property type="entry name" value="HTH_HARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH HARE-type" evidence="8">
        <location>
            <begin position="8"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="112"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="123"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="169" mass="20057" checksum="1A9E5CA9CA8E5279" modified="2004-07-05" version="1">MKKTKTPKSLLETAYDIMKKHHNPVSVYDLLKQTLQKHQIPNNNPNVANQLYLDIALSGKFVFCEDNQLIIKENNKLFWDKDFFEKTQISKDEPLDEDTNLQELDFEDFLSDKDTVQTDPLQDDLLDLEDEPSEEQNKDDDKIEDDIVLEDKDDYEEPLEEEYEHLYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="118" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPX2</accession>
    <name>Q6YPX2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">lpd</name>
        <name evidence="16" type="ordered locus">PAM_603</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_603"/>
    <dbReference type="EnsemblBacteria" id="BAD04688">
        <property type="protein sequence ID" value="BAD04688"/>
        <property type="gene ID" value="PAM_603"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_603"/>
    <dbReference type="eggNOG" id="COG1249">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016755_0_3_14"/>
    <dbReference type="OMA" id="DAKYGEW"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-727-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="4"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="338"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="138"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="179"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="309"/>
            <end position="312"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="41"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="BAD04688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="457" mass="49385" checksum="EBABE4A6B43D3184" modified="2004-07-05" version="1">MKNYDVLVIGGGPGGYVAAIKAAQMGAKVALVEKHKLGGICLNYGCIPTKAYLKSAKMYKDIKRCADFGIKVQNGVSFDWSSILSRKNKIVAQLTTGISFLLKKNKIDFYHGFASVLSPCEVQVDTNLLHTQKLIIATGSTAFVTPIPGAQEAYQKGILKTSKELLQLESYPSKVTIVGGGVIGVEFATIFNSFGSEVTILERQDNILNGMDRDVVVAYTKKLQADGIQILTQVEVTKINDNQTTYTQKGNAKTITSDVILMAVGTKANLAGLEKLNLALNRNSVQTDNFCQTSIPGVYAIGDVNGKHMLAHVASHEGIVAVTHALEQKAQPINYDRVPACIYGFPEIASIGMTEQQAKEKQMDYKVSKISLGAVGKSLADGEKEGFAKLIVCKKHLEILGMHIYAYNATELISEMAVGMELEGTAYELSQAIHPHPTLSELTFEALLGAVDKPIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPX8</accession>
    <name>Q6YPX8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">PAM_597</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_597"/>
    <dbReference type="EnsemblBacteria" id="BAD04682">
        <property type="protein sequence ID" value="BAD04682"/>
        <property type="gene ID" value="PAM_597"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_597"/>
    <dbReference type="eggNOG" id="COG0073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1487614_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="4">
        <location>
            <begin position="44"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="181" mass="19728" checksum="2AAFBE659C1AC331" modified="2004-07-05" version="1">MQGTPPTMKIIENILKNHFSQPLSQNISALTNNYITEVQNFFPLSKNTNLVVGQILNFQKIQGSQKLNLVEVNTGTKVVKIVCGASNLQNGKKVIVASEGSFLEGINATLKNKKIYGVFSEGMLCALEELGISTKFLTPQEQEGIYLFDDPNDQIALGSNALIPLGLDCFILELGLTPNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPY0</accession>
    <name>Q6YPY0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_595"/>
    <dbReference type="EnsemblBacteria" id="BAD04680">
        <property type="protein sequence ID" value="BAD04680"/>
        <property type="gene ID" value="PAM_595"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_595"/>
    <dbReference type="HOGENOM" id="CLU_2082428_0_0_14"/>
    <dbReference type="OMA" id="IYQKTTQ"/>
    <dbReference type="OrthoDB" id="1855044at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-720-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="117" mass="12715" checksum="268134E9A3264FE1" modified="2004-07-05" version="1">MNQKPRKALIKKNNLPQTNTPKKPFLSSKLLSNCIIFKSIVIVVLAIYLSKPTQTDIYQKTTQLHLTAMVAGMFLGGTILGLKKGSFGVSLGVLLGATLGMWLSLLTKGNIISIIQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ00</accession>
    <name>Q6YQ00_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_575"/>
    <dbReference type="EnsemblBacteria" id="BAD04660">
        <property type="protein sequence ID" value="BAD04660"/>
        <property type="gene ID" value="PAM_575"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_575"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1137139_0_0_14"/>
    <dbReference type="OrthoDB" id="1779749at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-695-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="244" mass="28946" checksum="04C85020E90C783B" modified="2004-07-05" version="1">MFNIKKIIKWFFIILGILLFLFIGFIVLTEMGIIKLPELPKKEIPSIKETVFENIEEWDYVNSGLKMIKAKYTFDGLNGIGYYQQQLANKDNINFYELGTIKDRLETQKEPPNLVCYIKDRHPFDRWNNRGLTYEETSVNGFEHAQFDMKDDSHLYSNINFEEQFKKDSGGNCLILKYKGPKDLIEKDKDYYLGRARVDDSNFKLTDFHLHFNPKRKTLSLYQNKHNNDKVKEAENNKRTSDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ24</accession>
    <name>Q6YQ24_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_551"/>
    <dbReference type="EnsemblBacteria" id="BAD04636">
        <property type="protein sequence ID" value="BAD04636"/>
        <property type="gene ID" value="PAM_551"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_551"/>
    <dbReference type="eggNOG" id="ENOG5033PU3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239554_0_0_14"/>
    <dbReference type="OMA" id="NIKQFNT"/>
    <dbReference type="OrthoDB" id="1406254at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-661-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.91.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038365">
        <property type="entry name" value="EcoRII_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="201" mass="23865" checksum="E08294B637DE6C69" modified="2004-07-05" version="1">MLNNQDFMNIKQFNTNIQTVDILKGFFKKTTFNLSVDKYMKTNHQQLNHYFNQNNIHSQSQKVIRGKINEYLILLYFQNKGIANLYPQVNLFFIPDIKFDLVLFTKNKRIIAFNFKTCLRDRYKQTMAEGQQLKKLDTRFEFYLLTNNETETQRLNKKINQGKVPGINQVINLFSNSANNFLQNLITTKFIPFSNINIIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ36</accession>
    <name>Q6YQ36_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_539</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_539"/>
    <dbReference type="EnsemblBacteria" id="BAD04624">
        <property type="protein sequence ID" value="BAD04624"/>
        <property type="gene ID" value="PAM_539"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_539"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1137139_0_0_14"/>
    <dbReference type="OrthoDB" id="1779749at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-645-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="243" mass="28998" checksum="ECCE7CDBD501E128" modified="2004-07-05" version="1">MFNIKKIIKWFFIILGILLFLFIGFIVLTEMGIIKLPELPKKEIPSIKETKMVIHEEWYDNNNKCTMIKAKYTFDGLNGIGYYQQQLQEKKGSHNDISIAQDRLEIQKEPSNLAKYIKDRYPFDRWNNRGLTYEETSVNEFEFSSFDTKNDSHLHYYINFEKQFKEESSGNCLILKYKGPKYLIEKDKDYYLGCAHVSNSNFKLTNFHLHFNPKRKTLSLYQDKHNKDKVKEAENNKRTSDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ37</accession>
    <name>Q6YQ37_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_538"/>
    <dbReference type="EnsemblBacteria" id="BAD04623">
        <property type="protein sequence ID" value="BAD04623"/>
        <property type="gene ID" value="PAM_538"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_538"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2118571_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="121" mass="14075" checksum="EE59B49C2AAB83CA" modified="2004-07-05" version="1">MQQGLHIEALEGTIKALENVSGKYIEENAELRHEINKLKEQIKDEQKAHEATKLNLKTESEKLTQKTEKLKKINLTIQEKKVSYSAAIQPLKACIKEDVRQRINSAKEKVNKVTSWFKKWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ46</accession>
    <name>Q6YQ46_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_529"/>
    <dbReference type="EnsemblBacteria" id="BAD04614">
        <property type="protein sequence ID" value="BAD04614"/>
        <property type="gene ID" value="PAM_529"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_529"/>
    <dbReference type="HOGENOM" id="CLU_155207_1_0_14"/>
    <dbReference type="OMA" id="SESMWGK"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="101" mass="11909" checksum="BFADCB4FC847D9CF" modified="2004-07-05" version="1">MDPSESMWEKIKEIAKLIFSVAVGGSVIYFLKEINNFLLNSFIKIGDLLFKIVLRILDIISIVLKFFLFLFKKVIIILSFFLSFFINFLYLWVFENAKKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="110" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ51</accession>
    <name>Q6YQ51_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA primase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dnaG</name>
        <name evidence="10" type="ordered locus">PAM_524</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_524"/>
    <dbReference type="EnsemblBacteria" id="BAD04609">
        <property type="protein sequence ID" value="BAD04609"/>
        <property type="gene ID" value="PAM_524"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_524"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620870_0_0_14"/>
    <dbReference type="OMA" id="WKCGRDY"/>
    <dbReference type="OrthoDB" id="1071997at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-628-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0639">Primosome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Toprim" evidence="9">
        <location>
            <begin position="301"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="441" mass="52605" checksum="20D812AC1D0F29D4" modified="2004-07-05" version="1">MNNQTKINHIKTNFPMSVLLKKLNILPPNFNDKYRFPCPIHQGQNPTTCHINENNNIHCWKCGRDYDVIDVYQEVRRNKNFPEVVNRIYHFMKTQEFKTLNQQEKESNKITTNPFKKPYQSQTSHPIDETQIQLIKNQLFKEISPLFNQIRDYYHYLLTSNRNNESHLGIEYLTQKRKLTLETIKEFKLGYAPLSNKPLSFRFINFLKKKNINIDKLLEYGFIKEKTNHQGTKYYHDTFHGSIIIPIENGYHQTFHFYQNHFRETSYFQPKYQSLTNFSQTPTFYFSYRFFEALPYIKQTKTIIIHEGFFDVISCYQYGIKNVVGLICVTQLLSQVQIEILKTENIKVIIALDNDETGRKRSEVLGKQLKLNQIPYEIRRILPPYDETCKDVDDLLRQYGKTAYQKCFLDPYITYEEARKKIIVDLAIHFFGKDKVEIINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ53</accession>
    <name>Q6YQ53_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_522</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_522"/>
    <dbReference type="EnsemblBacteria" id="BAD04607">
        <property type="protein sequence ID" value="BAD04607"/>
        <property type="gene ID" value="PAM_522"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_522"/>
    <dbReference type="eggNOG" id="ENOG5033PU3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239554_0_0_14"/>
    <dbReference type="OrthoDB" id="1643524at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-626-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.91.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038365">
        <property type="entry name" value="EcoRII_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="203" mass="24300" checksum="DBC637F9C3CA079A" modified="2004-07-05" version="1">MLTNTSFYHIKQFNTNAQCVNILKKLFYQTSFSFTFNKYMIHHHSLLDKYLTDNNYNSQSQKVIRGKINEYLILLYFQNQGIIHLYPQVYLFFIPDIKFDLVLFSQTKRIIAFNFKTCLRERYKQAMVEGQQLKKLDTRFEYYLLTNDATETQRLNNKITNGKVQGINQVINLFSPEANLFFKNLIQKNFIPFNNINLIKNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ56</accession>
    <name>Q6YQ56_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="Q6YQ56"/>
    <dbReference type="STRING" id="262768.PAM_519"/>
    <dbReference type="EnsemblBacteria" id="BAD04604">
        <property type="protein sequence ID" value="BAD04604"/>
        <property type="gene ID" value="PAM_519"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_519"/>
    <dbReference type="HOGENOM" id="CLU_2155782_0_0_14"/>
    <dbReference type="OMA" id="EERNTIM"/>
    <dbReference type="OrthoDB" id="2180815at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-622-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="111" mass="13256" checksum="D9E91DF4C26A656E" modified="2004-07-05" version="1">MFKFQHNLLFLNILLFIVLEMFLITNYFHQVMAAPKKHGKDIISSKEEVKDNVKKYYELYNTLENYSEEERNKIIQMLSDPAIIKTLEEKIKETKTHEKGSSYKKPDNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ62</accession>
    <name>Q6YQ62_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">himA</name>
        <name evidence="2" type="ordered locus">PAM_513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_513"/>
    <dbReference type="EnsemblBacteria" id="BAD04598">
        <property type="protein sequence ID" value="BAD04598"/>
        <property type="gene ID" value="PAM_513"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_513"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_3_14"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-615-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="96" mass="10969" checksum="47A535A0AD5C7492" modified="2004-07-05" version="1">MNKKELIKKIAEVNKTSISKTEEFYNSFENTLIKAIISNEEVSLSSKIGKFKLKPRKAYIGRNPKTKKKLKIPAKTVVTFKLSKTIKDQAKTLILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-12-02" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ74</accession>
    <name>Q6YQ74_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TsaD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_501"/>
    <dbReference type="EnsemblBacteria" id="BAD04586">
        <property type="protein sequence ID" value="BAD04586"/>
        <property type="gene ID" value="PAM_501"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_501"/>
    <dbReference type="eggNOG" id="COG1214">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064886_0_2_14"/>
    <dbReference type="OMA" id="SYTGTRV"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TsaD" evidence="1">
        <location>
            <begin position="70"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="237" mass="26853" checksum="14F7F9B21B077DD0" modified="2004-07-05" version="1">MIFKILIPKSTFKFFLQISNQTFESDTTMNHKNILILDTATKSQIVILVIQGKITTFKSRLGKNDYVPCMIPLIESVLQENNLGLNNLDALIVGVGPGSYTGTRVAVLTAKMLSFNLQIPLYQISSLLLLSSGYSYASLTPLIDVRSNAFFALSLKENHIYLNEDRFESSFLQSFPNHLLIEPTTIKIDFCTIKQFAKIVSNCHLLVPNYLTKTQAERNLEKNRLTKKVKIFLKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="126" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ76</accession>
    <name>Q6YQ76_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA gyrase subunit A</fullName>
            <ecNumber evidence="8">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">gyrA</name>
        <name evidence="11" type="ordered locus">PAM_499</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_499"/>
    <dbReference type="EnsemblBacteria" id="BAD04584">
        <property type="protein sequence ID" value="BAD04584"/>
        <property type="gene ID" value="PAM_499"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_499"/>
    <dbReference type="eggNOG" id="COG0188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002977_6_1_14"/>
    <dbReference type="OMA" id="THHWLLF"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-601-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01897">
        <property type="entry name" value="GyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005743">
        <property type="entry name" value="GyrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="10">
        <location>
            <begin position="25"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GyrA-box" evidence="8">
        <location>
            <begin position="539"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAD04584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="835" mass="94103" checksum="0AA168AA8516683B" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="132" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ77</accession>
    <name>Q6YQ77_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="4">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gyrB</name>
        <name evidence="8" type="ordered locus">PAM_498</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="4"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_498"/>
    <dbReference type="EnsemblBacteria" id="BAD04583">
        <property type="protein sequence ID" value="BAD04583"/>
        <property type="gene ID" value="PAM_498"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_498"/>
    <dbReference type="eggNOG" id="COG0187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006146_1_2_14"/>
    <dbReference type="OMA" id="LWETTMH"/>
    <dbReference type="OrthoDB" id="205481at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-600-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03366">
        <property type="entry name" value="TOPRIM_TopoIIA_GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034160">
        <property type="entry name" value="TOPRIM_GyrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Toprim" evidence="7">
        <location>
            <begin position="443"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="671" mass="76066" checksum="C357F1559A6544A3" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ78</accession>
    <name>Q6YQ78_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04582">
        <property type="protein sequence ID" value="BAD04582"/>
        <property type="gene ID" value="PAM_497"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_497"/>
    <dbReference type="HOGENOM" id="CLU_1584819_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="168" mass="19314" checksum="D7038A05C94A149E" modified="2004-07-05" version="1">MNKNCFGRLVGLGCCLCSFVVFFNCCNFFSFSFFFSYCFSCCISFGSGCSYFSFSNCATISKSFNCYFVKLWFSSCFGFNAFNSLSNNFFSNFSISVFSSFSCFFVFGNCFDCLSHFSFSILSSYSCFVSFFNCCNCLNNFIIFPPKFLLLELLLFQLLVLLQLFDKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ80</accession>
    <name>Q6YQ80_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC-type amino acid transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">artI</name>
        <name evidence="4" type="ordered locus">PAM_495</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_495"/>
    <dbReference type="EnsemblBacteria" id="BAD04580">
        <property type="protein sequence ID" value="BAD04580"/>
        <property type="gene ID" value="PAM_495"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_495"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_828576_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-597-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="4"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="335" mass="38201" checksum="2B2DD93A1F84B9D9" modified="2004-07-05" version="1">MNMPPLSFQGKDGTIGSDMAFCKELAKELGYKLDIKVYDGVEGLTTALNKKQVDFIIGSMNNTEKRQKNFDGINYLKATASILIKKNKKEFFQKFKLPNQELITLKNNNVELQDNEKIKLMLMEGSVFHIQIEKDHLINHKNNFKYEGTEADPKVLTNPDSAVCVNAVKDGIVDGFITDTPVAQGIANSDTTGELTTLEFVDNEFAEPAFEPFGFFIRQAQHNPKVSEEKFQQAVKAVYESSDQSEQTKYYNENFLKPATQDYIQIKQSNNSNGDKKTEITFWQKVWKTLPTYKKPFVFSFMAAIDSVIVGFLITLLFVKIKIYAEKQNKKIILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ83</accession>
    <name>Q6YQ83_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_250</name>
        <name evidence="2" type="ordered locus">PAM_492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">Onion yellows</strain>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04335">
        <property type="protein sequence ID" value="BAD04335"/>
        <property type="gene ID" value="PAM_250"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04577">
        <property type="protein sequence ID" value="BAD04577"/>
        <property type="gene ID" value="PAM_492"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_250"/>
    <dbReference type="KEGG" id="poy:PAM_492"/>
    <dbReference type="eggNOG" id="ENOG50323DM">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110632_0_0_14"/>
    <dbReference type="OMA" id="QAPLCLY"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="213" mass="24441" checksum="7566ACCC97ADEC40" modified="2004-07-05" version="1">MSHGPSIRYRKITKSDFRPCSTCKSCSQAPLCLYALQMISNHFEGTFERLRYSLGGDRPSQTAHQTLSLTLHMCRLETKNNKGGIPRTTPEKLAFFSHSFPPILYILFPISILSCSKAPWGLFVLSRVTGIFTGNLISPRLLLRQRPNRYAFRAGRNLPDKEFRYLRTVIVTAAVYWDFNSMLRCLTSPFNLPAPGRHQPLYITLRFSRDLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ84</accession>
    <name>Q6YQ84_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methylase_S domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">PAM_491</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_491"/>
    <dbReference type="EnsemblBacteria" id="BAD04576">
        <property type="protein sequence ID" value="BAD04576"/>
        <property type="gene ID" value="PAM_491"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_491"/>
    <dbReference type="HOGENOM" id="CLU_2288671_0_0_14"/>
    <dbReference type="OrthoDB" id="827072at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-577-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="5">
        <location>
            <begin position="10"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="101" mass="11706" checksum="89BC596822192095" modified="2004-07-05" version="1">MGGNKKTYSKGKSERANQNAGTITIGRDSGYVHYHEKPFWALSNCFIINTKNIKDLEYQTLYKLLQKNQKGIKNLKNLNKKGKNIKTKDLEFFLNSILNFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="123" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQA9</accession>
    <name>Q6YQA9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tryptophanyl-tRNA synthetase</fullName>
            <shortName evidence="8">TrpRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">trpS</name>
        <name evidence="10" type="ordered locus">PAM_466</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tryptophan to tRNA(Trp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="8"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_466"/>
    <dbReference type="EnsemblBacteria" id="BAD04551">
        <property type="protein sequence ID" value="BAD04551"/>
        <property type="gene ID" value="PAM_466"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_466"/>
    <dbReference type="eggNOG" id="COG0180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029244_1_1_14"/>
    <dbReference type="OMA" id="GWGQFKP"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="23"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="209"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="22"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="30"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="161"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="209"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="345" mass="39549" checksum="CC021404BD93A679" modified="2004-07-05" version="1">MQKIKKEVIKLIPNKRLVSGIKPTGDLTLGNYIGVLKPLLYLQQNLKNFDFYLFIADLHALTFYQEPQTLKQQIKKIAALYLATGLDPEKINLFVQSEVTQHTYLGYLLECNSYFSELQRMIQYKEKSKINAEGIRTSLFTYPTLMAADILIYDANLVPIGKDQKQHLELTKNLATRFNNLYGNTFVVPEPFFNPLGSKIKSLQNPLKKMSKSDTENPKSYILLLDDPQIIKSKIAQTVTDSQKIIKYDPENKPGISNLLTIYASLKQISIFESEKLFQKSNYKELKNKVGEEIINFVVPLQQKFYQLINSAKLDDILNKGAQKASLIAEKKIQQVRKKLGISRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQB7</accession>
    <name>Q6YQB7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_458"/>
    <dbReference type="EnsemblBacteria" id="BAD04543">
        <property type="protein sequence ID" value="BAD04543"/>
        <property type="gene ID" value="PAM_458"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_458"/>
    <dbReference type="HOGENOM" id="CLU_124827_0_0_14"/>
    <dbReference type="OMA" id="TQYIHDT"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="145" mass="16464" checksum="F2FFF8E278E32C59" modified="2004-07-05" version="1">MMNKKRKIFLNFWVIFIVIILLILLFLLGLRLPKLFKSIQDKNKVETQSQYKTQYIHDTNKVNNIIGLINSLKSLKTLNQLKPQTEKNDNEYQFQIESNDNNQLVKDIAVVSLTIVVGVISCVVLAPILASVGPIAAPIALLQFK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-06-07" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQC6</accession>
    <name>TIG_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trigger factor</fullName>
            <shortName evidence="1">TF</shortName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">PPIase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tig</name>
        <name type="ordered locus">PAM_449</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FKBP-type PPIase family. Tig subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQC6"/>
    <dbReference type="SMR" id="Q6YQC6"/>
    <dbReference type="STRING" id="262768.PAM_449"/>
    <dbReference type="EnsemblBacteria" id="BAD04534">
        <property type="protein sequence ID" value="BAD04534"/>
        <property type="gene ID" value="PAM_449"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_449"/>
    <dbReference type="eggNOG" id="COG0544">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033058_3_2_14"/>
    <dbReference type="OMA" id="KGIKTQF"/>
    <dbReference type="OrthoDB" id="932993at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-530-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00303">
        <property type="entry name" value="Trigger_factor_Tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005215">
        <property type="entry name" value="Trig_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008880">
        <property type="entry name" value="Trigger_fac_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037041">
        <property type="entry name" value="Trigger_fac_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008881">
        <property type="entry name" value="Trigger_fac_ribosome-bd_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036611">
        <property type="entry name" value="Trigger_fac_ribosome-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30560">
        <property type="entry name" value="PTHR30560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05698">
        <property type="entry name" value="Trigger_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05697">
        <property type="entry name" value="Trigger_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003095">
        <property type="entry name" value="Trigger_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102735">
        <property type="entry name" value="SSF102735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00115">
        <property type="entry name" value="tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0697">Rotamase</keyword>
    <feature type="chain" id="PRO_0000179399" description="Trigger factor">
        <location>
            <begin position="1"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="1">
        <location>
            <begin position="165"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00303"/>
        </source>
    </evidence>
    <sequence length="430" mass="49923" checksum="9B6CF4E69841C939" modified="2004-07-05" version="1">MEIKKINDQKVQYFFEVSSKELETQLASAYEKIKPKVEIKGFRKGHVPRKIFENRFGKDNLYSDALENIVQTKYQEVLQKKDFESMGMPQVIDLDEKKLKDNQNFTFGLEFIVKPKVTLKKYLGLEITKDDLEVTDYEVEEKINSLLEKQTTLESKTQNDFLELTDIAIFDFEGFVDDKPFEGGTAKDFSLEIGSGQFVPGFEDQMLGMKQGQTKDINITFPSDYHQKSLANQKAVFKVTLHQIKTKKIPQLTDNLVKSLKLVNASTVEELKNNTKQTLLAQKKHKEKENVEKQVIEQLVKNSELEIPQEIVSQEQIRLQKEFEAQLKQQNLTLEQYKQYLGIDDEKMEKEFSQQAQKNIEYQLIMEQVAAQEKLTISQEKIEQKYQNLSNHYKVPVNQIKQNLPEKNLKHSLLMGEALELVINKAVVAK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-01-15" modified="2022-08-03" version="112" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQD6</accession>
    <name>DNLJ_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA ligase</fullName>
            <ecNumber evidence="1">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ligA</name>
        <name type="ordered locus">PAM_438</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide.</text>
            <dbReference type="EC" id="6.5.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQD6"/>
    <dbReference type="SMR" id="Q6YQD6"/>
    <dbReference type="STRING" id="262768.PAM_438"/>
    <dbReference type="EnsemblBacteria" id="BAD04523">
        <property type="protein sequence ID" value="BAD04523"/>
        <property type="gene ID" value="PAM_438"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_438"/>
    <dbReference type="eggNOG" id="COG0272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007764_2_1_14"/>
    <dbReference type="OMA" id="HDVEHEI"/>
    <dbReference type="OrthoDB" id="241401at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-518-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NA-bd_OB-fold"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004149">
        <property type="entry name" value="Znf_DNAligase_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03119">
        <property type="entry name" value="DNA_ligase_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01055">
        <property type="entry name" value="DNA_LIGASE_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000313349" description="DNA ligase">
        <location>
            <begin position="1"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="588"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="1">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="35"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="84"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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    <feature type="binding site" evidence="1">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="406"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <sequence length="671" mass="75993" checksum="1A638C5DF8B03D53" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQD8</accession>
    <name>Q6YQD8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nfnB</name>
        <name evidence="2" type="ordered locus">PAM_435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
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            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_435"/>
    <dbReference type="EnsemblBacteria" id="BAD04520">
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        <property type="gene ID" value="PAM_435"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_435"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_4_5_14"/>
    <dbReference type="OMA" id="VNAQPWR"/>
    <dbReference type="OrthoDB" id="1847197at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-516-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="201" mass="22970" checksum="4D41F8F78AA994FE" modified="2004-07-05" version="1">MDFLKIKSVRQFCANHEIPNDILEAILATVFQAPSAFNLQPWRFFVFKGEKSKQKIAPFLHGNKTQLETCSTMILLCCDAQKSALAEKIYQQEVLQKKISDATKLQVITKIDDYYKQISQVKLQNELFLEGGIGALQLMLAAKKYDYDVCPMGGFNAKKINEGLNIDVRYLPVLLVAIGKSKEKPKNKAFRMDCKDFTFWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQF8</accession>
    <name>Q6YQF8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_415"/>
    <dbReference type="EnsemblBacteria" id="BAD04500">
        <property type="protein sequence ID" value="BAD04500"/>
        <property type="gene ID" value="PAM_415"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_415"/>
    <dbReference type="HOGENOM" id="CLU_155207_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-500-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="136" mass="15871" checksum="1CF291E8C2366278" modified="2004-07-05" version="1">MFDFLMQILKIFIDVFGSIIGYIKSSITSLTGQKLMDPSESMWEKIKEIAKLIFSFAVGGSVIYFLKEINNFLLNSFIKIGDLLFKIVLRILDIISIVLKFFLFLFKKVIIILSFVLSFFINFLYLWVFENAKKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQH2</accession>
    <name>Q6YQH2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_401"/>
    <dbReference type="EnsemblBacteria" id="BAD04486">
        <property type="protein sequence ID" value="BAD04486"/>
        <property type="gene ID" value="PAM_401"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_401"/>
    <dbReference type="HOGENOM" id="CLU_1804246_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-480-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="61"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="87"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="143" mass="17088" checksum="3F63282BBC8B7AEC" modified="2004-07-05" version="1">MKTTKKEFIDDYGSKVIQKYNAKKQLIEEIHHYRGDGPINYIIQYNPFTGHKLKQTKYHQNFLVDQIIKYDKVTGKEIKEKRYCQFDDKIINYIAKFDKMIGEFIKRFIYSSDGQTIEQIIEYDKKTNQQTIKTNQTKGVESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQH4</accession>
    <name>Q6YQH4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_399"/>
    <dbReference type="EnsemblBacteria" id="BAD04484">
        <property type="protein sequence ID" value="BAD04484"/>
        <property type="gene ID" value="PAM_399"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_399"/>
    <dbReference type="HOGENOM" id="CLU_1830964_0_0_14"/>
    <dbReference type="OMA" id="KCKNIEI"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-478-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="138" mass="16442" checksum="11903362D109A9B0" modified="2004-07-05" version="1">MKNKINALKTKLTKLKCKNIEIIQNNETKIKEINFDFKGIYEDSLQFLKIDFYSNANLRRVQCFSCRLDVNDKDFTYDFYDKNNPQVFKVCSFTLVPKVFKYLKAIGNILQREYFIPIMDVDEEITYNLISTKTLYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="117" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQH7</accession>
    <name>Q6YQH7_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_396</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_396"/>
    <dbReference type="EnsemblBacteria" id="BAD04481">
        <property type="protein sequence ID" value="BAD04481"/>
        <property type="gene ID" value="PAM_396"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_396"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-475-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="109" mass="12732" checksum="2DD3A4A694CD6795" modified="2004-07-05" version="1">MLNKVQLIGRIIHDLEKQYINSNNEQIPKIDFQLAVNLKEITQFIPCVVFRKQAENMKKYLHKGSKIYLEGLLSIQKYTNNEGQTKINTKVILQNVIFLDNKPQTTLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQJ6</accession>
    <name>Q6YQJ6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_377"/>
    <dbReference type="EnsemblBacteria" id="BAD04462">
        <property type="protein sequence ID" value="BAD04462"/>
        <property type="gene ID" value="PAM_377"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_377"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115275_0_0_14"/>
    <dbReference type="OrthoDB" id="1592351at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-451-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="211" mass="24750" checksum="2A0959A39DB29DBC" modified="2004-07-05" version="1">MTEQLQNQLQEQKTLIETKNKELINNQALSEQEKQALQQEINQLTTNFQQKEKEYQATIYQKDQEITHLNQIINEKANEINRLSEELEQQIDKVQQGLHIEALEGTIKALENVSGKYLEENAELRHEINKLKEQIKDEQKAHEETKVQLQTRSDNLTQKQEELTKIDLMIKAQENTYSGAIKPLTTKITNDAVKITKRTTEKVTSWFKSWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQJ8</accession>
    <name>Q6YQJ8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SF4 helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_334</name>
        <name evidence="3" type="ordered locus">PAM_375</name>
        <name evidence="4" type="ordered locus">PAM_545</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_334"/>
    <dbReference type="EnsemblBacteria" id="BAD04419">
        <property type="protein sequence ID" value="BAD04419"/>
        <property type="gene ID" value="PAM_334"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04460">
        <property type="protein sequence ID" value="BAD04460"/>
        <property type="gene ID" value="PAM_375"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04630">
        <property type="protein sequence ID" value="BAD04630"/>
        <property type="gene ID" value="PAM_545"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_334"/>
    <dbReference type="KEGG" id="poy:PAM_375"/>
    <dbReference type="KEGG" id="poy:PAM_545"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1609153_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="165" mass="19355" checksum="D21748E868C9067D" modified="2004-07-05" version="1">MSSCHPEFFEIDQQAKQKIQEEYYRLSETFKGLNQATKGFKKGQIITIGGYTGLGKTTFVYNVLLDIAKTKHQENSHYSHMLVFSYEMTMEENLSRLLANITQTPLEVILTKNFEDSNITTHTYMKRMNDAQQFFPQLNLSFSYDQGKKIDYIIDLVYRLHLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQL7</accession>
    <name>Q6YQL7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hflB</name>
        <name evidence="4" type="ordered locus">PAM_356</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_356"/>
    <dbReference type="EnsemblBacteria" id="BAD04441">
        <property type="protein sequence ID" value="BAD04441"/>
        <property type="gene ID" value="PAM_356"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_356"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="OrthoDB" id="977094at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-424-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="282"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="129"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="457" mass="52846" checksum="6FB31D0E977CEE3E" modified="2004-07-05" version="1">MTLNKKIYLSLIGLLSLGLLILLIFGITHSRPPTKNLSLTKQPSSTKQQKIENQIKLEQTKIKELQQKDYTLKTQIDENVKTLTDIITKIKTLQTELTNNPQLTPTIKTQKQQQLTELKTQQQTQQTLVDNLLEQRKALNQNQKEKQEELEKLAQEKAQLQTQENLQQQISQLNQALNYVEANQKRIEELKTQKEYRKNQTELKNLNDFQLFLTDQKLAFEKQKKNLTIQLNHLKENKPLPHTKKQVTFKDVYGMETEKEELDDLLSYFRTNQSLINFDKVRPKGYLLYGPPGTGKTFLIKALCGEANVHFINLIPSKFRQKYIGEGEKEVEKVWQEAENHDKTIIFIDEIEGLENRNDSNISSGGVNVINTLLDKLDGFNSSNKKIVLMGATNNLHKIDTALRSRFSKEIYIGNLKNSEIEGYLKHIIVPYQISYHTFLALKDITQLCQGVFVGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQL9</accession>
    <name>Q6YQL9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2963 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_354"/>
    <dbReference type="EnsemblBacteria" id="BAD04439">
        <property type="protein sequence ID" value="BAD04439"/>
        <property type="gene ID" value="PAM_354"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_354"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065991_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-422-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="134"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="359" mass="41850" checksum="43BB58FA13EF01B9" modified="2004-07-05" version="1">MSSFRIGNKHYKIIPFLITTGTLIFFVFWIGGLAYKYHLETEERRKLQEVDIKAKARELNNDIYNENKKLKKENEYMKDTPYEFQRDNGEKEYYNLFTNKLVKKIDKDDTIWEYDKNNGLLLKKTDRYNNVEEYGSHGKLIKKTLSDGVWMEYNPVNAKMMKRKNIDGSLEEFDDNSERFKEIDKNGKVKFFKTKLYKTVKDFEKLFINNKDLEKTFLESRIFNLEDLKDAGFTFKQLKATGYSLQELKDAGYTAQQLKDAGISLKELKEVGFIAKEIIDAGFTASQLVDAGFTVKDLRDSGIKLLKLINEGFTIPGMLGGGYTDKDFKDAGYILRKPSQFEFLKPKISDKGYIIEKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQN2</accession>
    <name>Q6YQN2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SF4 helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_341"/>
    <dbReference type="EnsemblBacteria" id="BAD04426">
        <property type="protein sequence ID" value="BAD04426"/>
        <property type="gene ID" value="PAM_341"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_341"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1609153_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="1">
        <location>
            <begin position="36"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="197" mass="22986" checksum="76EED105E8DACB82" modified="2004-07-05" version="1">MAFIPHKSDQTLLTLNQMSSCHPEFFDTDNQAKQKIQEEYYRLSEIFKGLNQSTKGFKKGQIITIGGYTGLGKTTFVYNLLLDIAKTKHQESSHYPHILVFSYEMTLEENLSRLLAHQTQIPLDIILDKNFQDFSIHDYTERMQTAKQFFANINLSFSYDKSKNIDYVIDLVYRLHLEQQAEIIVIDHLQITKPQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQR2</accession>
    <name>Q6YQR2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_311"/>
    <dbReference type="EnsemblBacteria" id="BAD04396">
        <property type="protein sequence ID" value="BAD04396"/>
        <property type="gene ID" value="PAM_311"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_311"/>
    <dbReference type="HOGENOM" id="CLU_2168401_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-371-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="110" mass="12995" checksum="AAE4E22A1E3F9E70" modified="2004-07-05" version="1">MDKQQKLKKEFYEHCQCCGSDLGININAACLNLFGFIMSFISFISCGILLLYSSLIFLLRYFFTVIIFNEEFFLTIGLISFISLFLFFLMARFMPKLLFEKLDYEKVEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQR6</accession>
    <name>Q6YQR6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflB</name>
        <name evidence="5" type="ordered locus">PAM_307</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_307"/>
    <dbReference type="EnsemblBacteria" id="BAD04392">
        <property type="protein sequence ID" value="BAD04392"/>
        <property type="gene ID" value="PAM_307"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_307"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_21_16_14"/>
    <dbReference type="OMA" id="IIESREH"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="212"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="422" mass="48932" checksum="BF09B1F162675F0F" modified="2004-07-05" version="1">METYLVFFKLFNKNKIIICFILPLSLILLFLISLELSYFWIEKNQLKNASLINIYELFAKFKANEIKKIHYTYKSQYSIWNKEHYLIQAESFDNQKYYCKMAASNYDYLVYAFYSYKDVLVEVKENIQFNFLELYFKFISYLVSFIFGFYILIHLKQMLSNKINKFNTNIDSSKDKITFADVAGLEEEKKEIQELIDFLKHPQKYHKMGFKIPKGVLLEGPPGTGKTLLAKALANEVKIPFYAVSGSEFVEVYVGVGASRIRDLFQKAKRTTPCIIFIDEIDALGAKRKNNSIIESREHDQSLNQLLLEMDGFFKLSQIIIIAATNRIDMLDPALIRPGRFDRKIKINLPNLKAREAILKVHAKNKNISLDVDFYKLALITEGASGAQLAAILNEALILAIRNNKDQIDKHFLEQAIKRILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQR7</accession>
    <name>Q6YQR7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dimethyladenosine transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ksgA</name>
        <name evidence="5" type="ordered locus">PAM_306</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_306"/>
    <dbReference type="EnsemblBacteria" id="BAD04391">
        <property type="protein sequence ID" value="BAD04391"/>
        <property type="gene ID" value="PAM_306"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_306"/>
    <dbReference type="eggNOG" id="COG0030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_601085_0_0_14"/>
    <dbReference type="OMA" id="KIRFVEY"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-365-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="455" mass="52613" checksum="0B5D4CD741D100D4" modified="2004-07-05" version="1">MKVSKVKITSFYKFFNSSFFSIYFIKIKKNLSSLLLVIFSSIILIWGLFDSCLQTHLDSFAYCKNIFHYTRQSIFLILVVAIIALTKYRTTKFYQILSFVALVNILIISLVFCDFIEDHKQHFISANWQMQLIPYYLQYVFAPLIYCFYVWKRPITFLGWKKVWIVFVHPFCYFLLSAIIFGFKADLKSHFINPYYQNNLTVAYFKLFVSFLLLAMGLIGVQKTKIHPFYKGALLVLGAFLICVIPRETSDWNHAKELVFYPQQMGSSLFPESQDIAKQLSNLVLEFEGKQDTGLKTGEKILELGAGSGNVTKYLVQKFGAQNVITLEYDKELCNVLRNKFPGLTVIEGDACNFIELLKKQIDETQIKQIKGIVSTLPLSIFSQEQLQELNKNLATVIKQNKIRFVEYRFLLFLREKHIIGDGVEEIQDTKNQIFVSSAILPTKVFIFAATDVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQT6</accession>
    <name>Q6YQT6_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Pyruvate kinase</fullName>
            <ecNumber evidence="4 12">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">pykF</name>
        <name evidence="15" type="ordered locus">PAM_287</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4 12"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_287"/>
    <dbReference type="EnsemblBacteria" id="BAD04372">
        <property type="protein sequence ID" value="BAD04372"/>
        <property type="gene ID" value="PAM_287"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_287"/>
    <dbReference type="eggNOG" id="COG0469">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015439_0_0_14"/>
    <dbReference type="OMA" id="QVPIVQK"/>
    <dbReference type="OrthoDB" id="1098983at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-345-MON"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 12 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="13">
        <location>
            <begin position="2"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="14">
        <location>
            <begin position="355"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="BAD04372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="446" mass="50088" checksum="748E3520F812FF58" modified="2004-07-05" version="1">MNKTKIICTLGPASYDKNILQALIQTGLNVARFNFSHAQYEQTKLLMKTIKTISDKLDKNTGLMLDTKGPEIRTHEFDGVVTIQKDSEVKISMTEVLGNAKLFSVSYSNLYNELKVGDMVNIDDGYLSLEVVGKDEAKQQLVTKAKNTHSIKSRRGVNVPKVNLEMDFISPKDYQDIVFAAQQDFDYIAASFVRRAQDVKDIRKILQEQGNSNIQIISKIENQEGVDNLEEIIQESDGIMVARGDLGIEVDGELVPLYQTRMITKCLEYGKPVVVATQMLESMQRNPRPTKAETSDVFNAVREGTTFTMLSGESASGEYPVEAVTYMKKINYQAEKVVNYQALSQVYQPKNSKENLLLSAVELALRTDVKAIVVYDLKDAYNVSKFHPSVPVLALVKTEQEARRLVLNFGVCPFVSETKLQTKLEELTQNQSSNCLVVKDGMLYFK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-07-19" modified="2022-08-03" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQT8</accession>
    <name>GPMI_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <shortName evidence="1">BPG-independent PGAM</shortName>
            <shortName evidence="1">Phosphoglyceromutase</shortName>
            <shortName evidence="1">iPGM</shortName>
            <ecNumber evidence="1">5.4.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gpmI</name>
        <name type="ordered locus">PAM_285</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQT8"/>
    <dbReference type="SMR" id="Q6YQT8"/>
    <dbReference type="STRING" id="262768.PAM_285"/>
    <dbReference type="EnsemblBacteria" id="BAD04370">
        <property type="protein sequence ID" value="BAD04370"/>
        <property type="gene ID" value="PAM_285"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_285"/>
    <dbReference type="eggNOG" id="COG0696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026099_2_0_14"/>
    <dbReference type="OMA" id="FMDGRDT"/>
    <dbReference type="OrthoDB" id="338375at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-343-MON"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046537">
        <property type="term" value="F:2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16010">
        <property type="entry name" value="iPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01038">
        <property type="entry name" value="GpmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011258">
        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="PTHR31637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001492">
        <property type="entry name" value="IPGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="SSF64158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0324">Glycolysis</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000212180" description="2,3-bisphosphoglycerate-independent phosphoglycerate mutase">
        <location>
            <begin position="1"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="154"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="253"/>
            <end position="256"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01038"/>
        </source>
    </evidence>
    <sequence length="512" mass="56799" checksum="911AA294A332059B" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-11-23" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQV6</accession>
    <name>RSMG_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase G</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA 7-methylguanosine methyltransferase</fullName>
            <shortName evidence="1">16S rRNA m7G methyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmG</name>
        <name type="ordered locus">PAM_267</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the N7 position of a guanine in 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQV6"/>
    <dbReference type="SMR" id="Q6YQV6"/>
    <dbReference type="STRING" id="262768.PAM_267"/>
    <dbReference type="EnsemblBacteria" id="BAD04352">
        <property type="protein sequence ID" value="BAD04352"/>
        <property type="gene ID" value="PAM_267"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_267"/>
    <dbReference type="eggNOG" id="COG0357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065341_0_0_14"/>
    <dbReference type="OMA" id="ICFPHLH"/>
    <dbReference type="OrthoDB" id="1590629at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-324-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="PTHR31760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003078">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00138">
        <property type="entry name" value="rsmG_gidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000184297" description="Ribosomal RNA small subunit methyltransferase G">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="96"/>
            <end position="98"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="124"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00074"/>
        </source>
    </evidence>
    <sequence length="212" mass="24766" checksum="5610EE9C5BA60FD0" modified="2004-07-05" version="1">MLYFESLKDKFALNEKQLNKFVFYYEFLKQENQKMNLTSIISLSDVCYKHFYDSLILKEIFNFNTVTNLCDVDSGAGFPSFPLKILFPHLKIVIIESSLKKINFLKQLSSHLELDNICFFHQRVEQYDIAKNGSYDCVVARALARLELILKWCVPLVKKKGYFIAMKGKNFQQELEASKKIIKQIRVKLVSAKTLELPMQLGTRTNLLFQNE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQW5</accession>
    <name>RL10_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplJ</name>
        <name type="ordered locus">PAM_258</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQW5"/>
    <dbReference type="SMR" id="Q6YQW5"/>
    <dbReference type="STRING" id="262768.PAM_258"/>
    <dbReference type="EnsemblBacteria" id="BAD04343">
        <property type="protein sequence ID" value="BAD04343"/>
        <property type="gene ID" value="PAM_258"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_258"/>
    <dbReference type="eggNOG" id="COG0244">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092227_2_0_14"/>
    <dbReference type="OMA" id="VRDQKQA"/>
    <dbReference type="OrthoDB" id="1470978at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-315-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00362">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022973">
        <property type="entry name" value="Ribosomal_L10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000154680" description="50S ribosomal protein L10">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00362"/>
        </source>
    </evidence>
    <sequence length="169" mass="18879" checksum="B2971A49759A67E3" modified="2004-07-05" version="1">MIKPQLSKKIDSVAVLQEKISTAKTVIVFEYASLPVSSFMQLRRELKKTSCEVKVYPKNIMQRAVTNAKQDDLVTFLKGAKALIISPQELLEPIKTIYNFAKKNKAVKIVSGIVEQKIVSLQEIKTLATLPSKEQMLALLAASMFAPLQHLAIGLNMLVQTKKQENPQQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQW6</accession>
    <name>RL1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplA</name>
        <name type="ordered locus">PAM_257</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04342" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04342.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQW6"/>
    <dbReference type="SMR" id="Q6YQW6"/>
    <dbReference type="STRING" id="262768.PAM_257"/>
    <dbReference type="EnsemblBacteria" id="BAD04342">
        <property type="protein sequence ID" value="BAD04342"/>
        <property type="gene ID" value="PAM_257"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_257"/>
    <dbReference type="eggNOG" id="COG0081">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062853_0_0_14"/>
    <dbReference type="OMA" id="GWTDVDV"/>
    <dbReference type="OrthoDB" id="1671455at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-314-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0810">Translation regulation</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_0000125703" description="50S ribosomal protein L1">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="230" mass="25333" checksum="94662E65231BC888" modified="2005-03-15" version="2">MKRGKKYLASLQMFDVKKTYPLQEAISLAKQTQVAKFDAAVECAFHLNLDPKKVDQNLRGALVLPHGTGKVLKVAVLAKGEQAKQAQEAQADYVGDQDLIDKIAKNWFDFDVLVATPEMMPQLSKLGRLLGPKGLMPNPKTGTVTNDVLQAVKEIKNGKIEYRLDKSGNIHAILGKVSFDETKLLENLKTLYLQLMAVKPRTVKGTYIKSVTISTTMAPGIKIDPVTISQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-04-29" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQX2</accession>
    <name>PNP_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Polynucleotide phosphorylase</fullName>
            <shortName evidence="1">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pnp</name>
        <name type="ordered locus">PAM_251</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQX2"/>
    <dbReference type="SMR" id="Q6YQX2"/>
    <dbReference type="STRING" id="262768.PAM_251"/>
    <dbReference type="EnsemblBacteria" id="BAD04336">
        <property type="protein sequence ID" value="BAD04336"/>
        <property type="gene ID" value="PAM_251"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_251"/>
    <dbReference type="eggNOG" id="COG1185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004217_2_2_14"/>
    <dbReference type="OMA" id="LHILDVM"/>
    <dbReference type="OrthoDB" id="122725at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-308-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000329745" description="Polyribonucleotide nucleotidyltransferase">
        <location>
            <begin position="1"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="KH" evidence="1">
        <location>
            <begin position="565"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="635"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="498"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <sequence length="715" mass="80121" checksum="F77537184C982E9B" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQX9</accession>
    <name>Q6YQX9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rpmG</name>
        <name evidence="5" type="ordered locus">PAM_244</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_244"/>
    <dbReference type="EnsemblBacteria" id="BAD04329">
        <property type="protein sequence ID" value="BAD04329"/>
        <property type="gene ID" value="PAM_244"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_244"/>
    <dbReference type="eggNOG" id="COG0267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190949_0_2_14"/>
    <dbReference type="OrthoDB" id="2034291at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-293-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_L33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168">
        <property type="entry name" value="PTHR43168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="49" mass="5989" checksum="154BEE0D89BFBBFA" modified="2004-07-05" version="1">MRDLVKLVCTECKRENYHTDKNKKKTPGRLELKKYCPFSRTHTLHREKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQZ1</accession>
    <name>Q6YQZ1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmI</name>
        <name evidence="8" type="ordered locus">PAM_232</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_232"/>
    <dbReference type="EnsemblBacteria" id="BAD04317">
        <property type="protein sequence ID" value="BAD04317"/>
        <property type="gene ID" value="PAM_232"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_232"/>
    <dbReference type="eggNOG" id="COG0313">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044779_1_0_14"/>
    <dbReference type="OMA" id="RTMVFFE"/>
    <dbReference type="OrthoDB" id="1059309at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-278-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018063">
        <property type="entry name" value="SAM_MeTrfase_RsmI_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01296">
        <property type="entry name" value="RSMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="14"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="285" mass="32357" checksum="BBAA8ECE52C63FCF" modified="2004-07-05" version="1">MLFQQQSFCNAKPTLYLVATPIGNLQDITLRALATLKEVFLILAEDTRRAKKLLHTYQIQTPLLSYYEHNQTRRLPQILELLSQGKNIALISDAGTPLISDPGFSLVCEVQKHGFNVVAIPGVSAFLTAFMTSAIPSPFIFLAFLPRLSQALEKYLLQYKNASESLVIYESPHRIKKTLLLIHKLYGNRKISLARELTKKFETIINGNLDSILEFDLINKGEYVIVVAGNPNPNEHLLALSINDHVLFYLKLGFNEKEAFSKVAQERNITKKEIYHQYKIKNPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQZ2</accession>
    <name>Q6YQZ2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase III, delta prime subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">holB</name>
        <name evidence="1" type="ordered locus">PAM_231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_231"/>
    <dbReference type="EnsemblBacteria" id="BAD04316">
        <property type="protein sequence ID" value="BAD04316"/>
        <property type="gene ID" value="PAM_231"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_231"/>
    <dbReference type="eggNOG" id="COG0470">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_846348_0_0_14"/>
    <dbReference type="OMA" id="YPNFYYL"/>
    <dbReference type="OrthoDB" id="1971388at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-277-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="329" mass="38461" checksum="B58B85A143C0027B" modified="2004-07-05" version="1">MNKTQSLLAKFNQIIQNNKLAHLYLVVGSTLSRQKLFVLELAYRIFKPHDPHLLKKDTLLNSQYPNFYYLTKQNHLFTKEQILQFQKNFLQTSLFGTQRIYVIEEIEKITTQTSNSLLHFFENPSNNNTIGFLLTNNLEQVLPTIVSRCQIINISDTVDAKSQNLDSKTKSQIDAFDFSLSNLINKNSDQMDLFVASDYYQNFKQFFLDFLIQFPKTISLKLAVFASPLLAKLISCPHFLNDFLSVLLRFFSDILYEKTPNSKTPIYFSKTQILTNPEYQKYYQTLPLPTTFNILKIIHQIYKKQNILSNQENLFMALLIQLEAQRLSF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-01" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR01</accession>
    <name>KAD_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenylate kinase</fullName>
            <shortName evidence="1">AK</shortName>
            <ecNumber evidence="1">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">adk</name>
        <name type="ordered locus">PAM_221</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR01"/>
    <dbReference type="SMR" id="Q6YR01"/>
    <dbReference type="STRING" id="262768.PAM_221"/>
    <dbReference type="EnsemblBacteria" id="BAD04306">
        <property type="protein sequence ID" value="BAD04306"/>
        <property type="gene ID" value="PAM_221"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_221"/>
    <dbReference type="eggNOG" id="COG0563">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032354_1_2_14"/>
    <dbReference type="OMA" id="FHNRMRV"/>
    <dbReference type="OrthoDB" id="1491686at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-267-MON"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000158820" description="Adenylate kinase">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMP" evidence="1">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="1">
        <location>
            <begin position="126"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="136"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <sequence length="217" mass="24910" checksum="A05611B907E84894" modified="2004-07-05" version="1">MILILLGPPGIGKGTQASVLSDILKINHIATGDIFRKNFKENTELGILIKKIIAQGLLVPDDITNQMIADYLSKDIATKDFLLDGFPRNVLQARFLDDFFKNSHLFLTKVIYFNAGTQDLMKRIVGRRICPECGKVYHIENIPPKTPGICDKDQKTLIQREDDKPETFLKRLKVFNQETLPLVQYYREQNQLFEVDGMQNIDQVTKMILEVLETDRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-05-02" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR12</accession>
    <name>RS17_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsQ</name>
        <name type="ordered locus">PAM_209</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR12"/>
    <dbReference type="SMR" id="Q6YR12"/>
    <dbReference type="STRING" id="262768.PAM_209"/>
    <dbReference type="EnsemblBacteria" id="BAD04294">
        <property type="protein sequence ID" value="BAD04294"/>
        <property type="gene ID" value="PAM_209"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_209"/>
    <dbReference type="eggNOG" id="COG0186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073626_1_0_14"/>
    <dbReference type="OMA" id="HPMYGKF"/>
    <dbReference type="OrthoDB" id="2035880at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-255-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000233526" description="30S ribosomal protein S17">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <sequence length="87" mass="10253" checksum="406D671D0A26A294" modified="2004-07-05" version="1">MQRNFRKTFVGKVVSDKMDKTITVIVDIYKKDPLYGKRVKQSKKFHVHDENQEAKPGDLVNFMETRPLSKTKRFRLFKILSHAKSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="126" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR26</accession>
    <name>Q6YR26_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type dipeptide/oligopeptide transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dppD</name>
        <name evidence="6" type="ordered locus">PAM_192</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_192"/>
    <dbReference type="EnsemblBacteria" id="BAD04277">
        <property type="protein sequence ID" value="BAD04277"/>
        <property type="gene ID" value="PAM_192"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_192"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_14"/>
    <dbReference type="OMA" id="PHGRVKA"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-236-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="267" mass="29983" checksum="0D11F602BAD41348" modified="2004-07-05" version="1">MSLLKVSNLHTYFETQKGLIKAVRGVSFEVQKGKTLGIVGESGSGKSQTAISILKLFEKNQKIYQGEITFEKRIISQFSEKEMQKIRGNEIAMIFQDAISSLNPVFKIKNQIIEVLMLHQKLDYTQAYQKTLDILEKVQIPNAQRVMNSYPHQLSGGMCQRIMIAMALVCKPKLLIADEATTALDVIVQKEILNLIACLQQEQNTAVLFITHDLGVVSQVADDIIVMYQGQIVESAKTSQILKNPKHPYTKSLLNNFLKTGLGYHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR30</accession>
    <name>Q6YR30_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zn-dependent carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_188"/>
    <dbReference type="EnsemblBacteria" id="BAD04273">
        <property type="protein sequence ID" value="BAD04273"/>
        <property type="gene ID" value="PAM_188"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_188"/>
    <dbReference type="eggNOG" id="COG2317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2570448_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="81" mass="9537" checksum="DB3AE6F5683EDAA2" modified="2004-07-05" version="1">MSINYQKLEQRFEKIGRLENIINILNWDMACNIKKGSQESRTLEIIDLTQIIKKLLTSQRNQKFAFTNTTRTRNSQFLATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="124" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR43</accession>
    <name>Q6YR43_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gapA</name>
        <name evidence="10" type="ordered locus">PAM_175</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_175"/>
    <dbReference type="EnsemblBacteria" id="BAD04260">
        <property type="protein sequence ID" value="BAD04260"/>
        <property type="gene ID" value="PAM_175"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_175"/>
    <dbReference type="eggNOG" id="COG0057">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030140_0_0_14"/>
    <dbReference type="OMA" id="NCVAPMA"/>
    <dbReference type="OrthoDB" id="944149at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-214-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="213"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="335" mass="36577" checksum="F6AF284FF17C674E" modified="2004-07-05" version="1">MKVKVAINGFGRIGKLAFRLVFGNPKFEVVAINDLATLETISYLLKYDSIQKPYKLDAVSFEDNYLVVEGQKIPVFQEKNPQDLPWKKLGVDIVLECTGFFTSKEKAALHLEAGAKKVLISAPATGDVKTVVYNVNDQILTKEDAIVSGASCTTNCLAPVVKVLNDNFGINQAFMTTVHSYTSDQSLIDQNHPKGIWTRRGRAAAFNMVPSSTGAAKAISLVIPELKGKLDGTAIRVPTITGSLVDLTAELTQEATPEAINEAFKKAANGTLAYVTDPIVSSDVIGTSYGSLYDSHTLQVLKEKPKFIKLMSWYDNEMSYVSQLVRLLHKVATLV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR51</accession>
    <name>RS2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsB</name>
        <name type="ordered locus">PAM_165</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR51"/>
    <dbReference type="SMR" id="Q6YR51"/>
    <dbReference type="STRING" id="262768.PAM_165"/>
    <dbReference type="PRIDE" id="Q6YR51"/>
    <dbReference type="EnsemblBacteria" id="BAD04250">
        <property type="protein sequence ID" value="BAD04250"/>
        <property type="gene ID" value="PAM_165"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_165"/>
    <dbReference type="eggNOG" id="COG0052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040318_1_2_14"/>
    <dbReference type="OMA" id="SYIDRAY"/>
    <dbReference type="OrthoDB" id="1623045at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-204-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000134209" description="30S ribosomal protein S2">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="240"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="271" mass="30928" checksum="FA68BD2BCE9933A8" modified="2004-07-05" version="1">MAVVTTKQLLESGVYFGHATRKWNPKMKPYIFTSRNGIHIINLKKTSEEIEKAYQELLNIITSGGKALFLGTKKQIQSAIREEAQRSQQYYVDHRWLGGTLTNFKTILKRIELLHLLHKQEEEGLWKKLPKKEVVQLKRKRDKLEKFLGGIKDMKDLPQAIFVVDPEKESIAVAEARKLGIKVFGIVDTNCDPDLVDYIIPANDDAIRGVKLIIWLMANACVEGTGGVAEKAETFDAKNPLKPQNYNAPNKRPYQDSPRKPSYQNQNQNQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR52</accession>
    <name>Q6YR52_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">dUTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dut</name>
        <name evidence="5" type="ordered locus">PAM_164</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_164"/>
    <dbReference type="EnsemblBacteria" id="BAD04249">
        <property type="protein sequence ID" value="BAD04249"/>
        <property type="gene ID" value="PAM_164"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_164"/>
    <dbReference type="eggNOG" id="COG0756">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068508_0_0_14"/>
    <dbReference type="OMA" id="HIFWTDI"/>
    <dbReference type="OrthoDB" id="1669228at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-203-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="4">
        <location>
            <begin position="20"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="150" mass="17024" checksum="21694C91F0DE7E65" modified="2004-07-05" version="1">MNKTNRFFEKVSSYQNQGINLPQRQTKFSAGYDFEAAQSMEIPPQTFILVPTGIKASFPWNEVLLIYVRSSLPLKKQLTLANGVGVVDSDYYNNLQNEGHIFIALYNFSKNPVQVCKGERIAQGIFQPFFQITQEKENNFARKGGFGSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR65</accession>
    <name>Q6YR65_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">rbfA</name>
        <name evidence="2" type="ordered locus">PAM_151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RbfA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_151"/>
    <dbReference type="EnsemblBacteria" id="BAD04236">
        <property type="protein sequence ID" value="BAD04236"/>
        <property type="gene ID" value="PAM_151"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_151"/>
    <dbReference type="eggNOG" id="COG0858">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089475_3_1_14"/>
    <dbReference type="OMA" id="SFANVYY"/>
    <dbReference type="OrthoDB" id="1971380at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-183-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="113" mass="13133" checksum="D4D605BA03813C3E" modified="2004-07-05" version="1">MVTTAERLSSLIQKELVLINDVIQDEQIGYINLTDVKVTKDLSFANVYYTILSDDPTVLKLTEETIEQNKVVIRLELAKKIKNFRKIPDLVFKYDKSLSYGRRIENILKDINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="114" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR74</accession>
    <name>Q6YR74_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uridine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">udk</name>
        <name evidence="3" type="ordered locus">PAM_142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_142"/>
    <dbReference type="EnsemblBacteria" id="BAD04227">
        <property type="protein sequence ID" value="BAD04227"/>
        <property type="gene ID" value="PAM_142"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_142"/>
    <dbReference type="eggNOG" id="COG0572">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023775_1_0_14"/>
    <dbReference type="OMA" id="DDHNRIP"/>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-174-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="2">
        <location>
            <begin position="285"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="546" mass="63753" checksum="6A4DFF8BB29A86A6" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR83</accession>
    <name>Q6YR83_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type uncharacterized transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nlpA</name>
        <name evidence="5" type="ordered locus">PAM_133</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NlpA lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_133"/>
    <dbReference type="EnsemblBacteria" id="BAD04218">
        <property type="protein sequence ID" value="BAD04218"/>
        <property type="gene ID" value="PAM_133"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_133"/>
    <dbReference type="eggNOG" id="COG1464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_798851_0_0_14"/>
    <dbReference type="OMA" id="FAKPNTF"/>
    <dbReference type="OrthoDB" id="884213at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-165-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004872">
        <property type="entry name" value="Lipoprotein_NlpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03180">
        <property type="entry name" value="Lipoprotein_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="347" mass="39996" checksum="8AF1A3CAD47EEA4D" modified="2004-07-05" version="1">MFKLSSLSSKTKKNLLFALLTISLLCNLLLGYFLWDAKKSLAHTPSNQKNHKLTVATALPTIKYFLEEYAKDRLKEYNIDLDVQYISSRFKQTNELLLNKKVDAKLDAHVHDLNIFNKENPNIPDQDKLTFSQVVYLAKFGLFAKPNTFNNLEGIKKNNHPNNLKILMPQDNFQRSLALRVLQELKIIEEINPERTLSTEEQFNLKTTDFKPTNLYPDIEYTTESDLMTITSRFLAPNDFDLCLNYPTLMGLGINNFISLGIMQKPTNLDDIIYSYTISLVTTNNNKNNWKIKILQDILKEEEAIAYMKKSQFATNFYMIPRQEVKQISKNIKDKYLGKTGAAPASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR91</accession>
    <name>Q6YR91_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nadE</name>
        <name evidence="1" type="ordered locus">PAM_124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_124"/>
    <dbReference type="EnsemblBacteria" id="BAD04209">
        <property type="protein sequence ID" value="BAD04209"/>
        <property type="gene ID" value="PAM_124"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_124"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_857478_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-156-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041856">
        <property type="entry name" value="NAD+_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="324" mass="37012" checksum="D305488A2E813D7D" modified="2004-07-05" version="1">MANEIQVLALKTKLSNLNAKIIVEITENINDLLTLVVAFQSFSLLQKPLEDFIVILNPLLFSNQTHYQLLKDFLQTKGVFHICESSFLKKKDLLAFLGLDKTDATTNTTNLTDATNDTSATNEINEANETATLFNDINNISTLSNELASCSKDLDQVFLKELASQTQKFLLLENNNFSDMALGKNNPRSHYDHIYNVNAGVPNVLVKELLLYHLEKNYLQIAPALKKLYQKLVQENINQKLIMEDFILCCRIKKGFTKTKIAWLLQIAFDLSPEKSNQLVVSYLKTFYQNQFKRQNMAPGPKVLENSLSPRNEFLLPIYLQRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR97</accession>
    <name>Q6YR97_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_118"/>
    <dbReference type="EnsemblBacteria" id="BAD04203">
        <property type="protein sequence ID" value="BAD04203"/>
        <property type="gene ID" value="PAM_118"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_118"/>
    <dbReference type="HOGENOM" id="CLU_1123644_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-150-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="247" mass="28847" checksum="E926D47A9614FF55" modified="2004-07-05" version="1">MNFEIEFLQEELNKLNEKQSQPKPLQPPTSSTLQTSESNASSTPPQDVTPTPPNSEQQPQQPNPEAEKLKQQIKDKQKEKEELLQKEDPLKLEEDITKLVQKLAQLDQEKKPFKAKVKQLQKDLEKEVRVVDLRAAFYQVYGMKILNTPEERCNELQELAKVYNKRNTQVLYSTQAMHYFNQTLNPKINQLMEEAQCDKLIAYFVEASKRKFLETNQTLQQNDLDEVFKEVYGGLDELTQKLNNNYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR98</accession>
    <name>Q6YR98_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hflB</name>
        <name evidence="4" type="ordered locus">PAM_117</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_117"/>
    <dbReference type="EnsemblBacteria" id="BAD04202">
        <property type="protein sequence ID" value="BAD04202"/>
        <property type="gene ID" value="PAM_117"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_117"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_683026_0_0_14"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-149-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="100"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="308"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="403" mass="46228" checksum="C558646A2F73491E" modified="2004-07-05" version="1">MTIQELQQMMEDIIHGNNLHTLNDLINALANKNDPSKKQLQHIDKFPEGTRYFPMPLDEFEGLPSFKKTIGMESVIDQLQGFLNYLSDPLSYVVVGKVKPPQGVLFYGVPGTGKTFFTRALAKEAGRQVGFYETNAAEFVYQTLVGDGPRFVKKLFEDVRLHNKKEGVKASIIFIDECEEAFKYLNKTANSSSDLPNVVNQFKTELTSTKNDPKKPILIIGATNYFDKIDEAIKSRFTYHIEIKVGDATARAKYLDLMINVLRKNPFHEEALEYLLKTVNPFLDKFDAESRSNRRLENMIESSVINMNNRLSAESRAKQKEIDDKTKKLQLEANTLSLSQEEKDQLQKDIQELKTQLHNRKIKLEQIVENESQMAQIKQQETKIEKETAEKKAQQIILEEKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRA4</accession>
    <name>Q6YRA4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_111"/>
    <dbReference type="EnsemblBacteria" id="BAD04196">
        <property type="protein sequence ID" value="BAD04196"/>
        <property type="gene ID" value="PAM_111"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_111"/>
    <dbReference type="HOGENOM" id="CLU_1439731_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="188" mass="21513" checksum="13277B9381F4523C" modified="2004-07-05" version="1">MVIVNMSKYKKISILTTFLKHVKKTVYILYIVFFIILLSHCNFNILLANDSDPNYLGVIQPRQLGINGNSNIGYKIQTDNKTKLEVQIKPLASDNKNLFYFQGDAKTIGQEPNAASTYKRGYALLVTIPQKSCLDEQDLYLCCDANIAIKQEAYEAFLKAQTDVEKLLSNDQKTKDYWEVQKKTEELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRA8</accession>
    <name>Q6YRA8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04192">
        <property type="protein sequence ID" value="BAD04192"/>
        <property type="gene ID" value="PAM_107"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_107"/>
    <dbReference type="HOGENOM" id="CLU_2082426_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-138-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="117" mass="13345" checksum="B70E3C1A6550FD1E" modified="2004-07-05" version="1">MFAKKNLLIVFVCSLIAMLFSLLVFVIVVSKLGYLSFKDVKETNLSKDIKSPKTQEQRDNKTNQLAQRVAEQVKEQFQLTTLTESQIKEIKDGKIVLSKEQLEAIKGELKPLVDLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRB8</accession>
    <name>Q6YRB8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type uncharacterized transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nlpA</name>
        <name evidence="5" type="ordered locus">PAM_097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NlpA lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_097"/>
    <dbReference type="EnsemblBacteria" id="BAD04182">
        <property type="protein sequence ID" value="BAD04182"/>
        <property type="gene ID" value="PAM_097"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_097"/>
    <dbReference type="eggNOG" id="COG1464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1011347_0_0_14"/>
    <dbReference type="OMA" id="LMANWPA"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-129-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004872">
        <property type="entry name" value="Lipoprotein_NlpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03180">
        <property type="entry name" value="Lipoprotein_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="275" mass="31720" checksum="4CEAD48EEDBD3332" modified="2004-07-05" version="1">MQSVVNTLNKARDLVKKDGIDLQVTKVNYYTEGTDLISSGKADGLIYFNIHVLNYHNEILKTNNKEMFEYVQAFYYSKYGLYINKNRNPVLKDLEDVKKHSNLKVLLAVAFSYIGPCDTPRSLVLLNKLGLIKIDPKVLQEKKFGISFEDLQNHYNLEFIKASQIPDKFAQNPQKYDLMANWPAFMNPYPYFVRIGATIEGNEEPTDDFIASYDIGLSCLKSHKDSEQIKTLKAILNNPQVKEFHLQEGGAQQDYFMVKAPEKTTKHIKELWLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRC4</accession>
    <name>Q6YRC4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04176">
        <property type="protein sequence ID" value="BAD04176"/>
        <property type="gene ID" value="PAM_091"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_091"/>
    <dbReference type="HOGENOM" id="CLU_899651_0_0_14"/>
    <dbReference type="OMA" id="DGSNNFC"/>
    <dbReference type="OrthoDB" id="1143487at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-122-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="309" mass="36208" checksum="03E7F3B64A15E89B" modified="2004-07-05" version="1">MQIQRKAIMRLFPKYFTLILFMILLGIHFCNQISIYAGKQQQLENIQEKENGGGVEKNANNTKQKPQIINNLPLKNLKNPKNFEQLFPLEKRTINDFSYYKQNNQLTKEDIIIALNGILKEINKESNIQIQSDDFEIASEQLEEKYESEEMQWQGSFQIEDILGNKIEFNFTKKTINLEDIITNAHLGTIQITPNITDEQRKQLICEAIWQKNPQLKNKFLPKDFQFSKNKDGSNNFCKIEYDLAKEDQYHEYESEMELEINYQQETNAASTTKTTTTNSIIFYTIITIITGLIVAFLLILIYKIKHQK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-10-13" modified="2022-08-03" version="118" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRC6</accession>
    <name>OBG_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GTPase Obg</fullName>
            <ecNumber evidence="1">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">obg</name>
        <name type="ordered locus">PAM_089</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRC6"/>
    <dbReference type="SMR" id="Q6YRC6"/>
    <dbReference type="STRING" id="262768.PAM_089"/>
    <dbReference type="EnsemblBacteria" id="BAD04174">
        <property type="protein sequence ID" value="BAD04174"/>
        <property type="gene ID" value="PAM_089"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_089"/>
    <dbReference type="eggNOG" id="COG0536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011747_2_1_14"/>
    <dbReference type="OMA" id="VVFDWEP"/>
    <dbReference type="OrthoDB" id="603226at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-118-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036346">
        <property type="entry name" value="GTP-bd_prot_GTP1/OBG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015349">
        <property type="entry name" value="OCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09269">
        <property type="entry name" value="DUF1967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102741">
        <property type="entry name" value="SSF102741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03595">
        <property type="entry name" value="Obg_CgtA_exten"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51881">
        <property type="entry name" value="OCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000386103" description="GTPase Obg">
        <location>
            <begin position="1"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Obg" evidence="3">
        <location>
            <begin position="4"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="1">
        <location>
            <begin position="162"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="OCT" evidence="2">
        <location>
            <begin position="345"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="168"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="193"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="214"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="281"/>
            <end position="284"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="308"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01231"/>
        </source>
    </evidence>
    <sequence length="422" mass="46507" checksum="79DF9BE452894409" modified="2004-07-05" version="1">MFSLHFVDEAFNEVFAGNGGHGIVAFRREKYVAFGGPAGGNGGKGGSVIFVGDKDETTLLKLKYQKHLKAPHGINGKNKGQNGANAPHLYVKVPLGTVFYTADNKFLGEILYDQQTLVIAKGGKGGKGNKALATFKNQAPSYAEKGDLGESFKIKTELKVLADIGLLGFPSVGKSSLISAISKAQPKVASYPFTTIKPHLGVVEVDGFSFVVADLPGLIANAHLGCGMGIQFLKHIERCRVLVHILSMESANPYQDFQTLNQELSQYNPQLLLKKQIIVTNKMDLPDALQKLTLLKQQIKDQPIIPLSLVSFDNLETLKYEMSSLLQNTPLEVAPNKNNDFKLYTLPDNQNTISVIKESDSVFVVSGKQVETFFHRTDFNNEEAVKRFNRILKKIGMEEQLQKQGAKPGDQVKICDRLFYFL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-01-09" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRC9</accession>
    <name>RL21_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplU</name>
        <name type="ordered locus">PAM_086</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04171" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04171.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRC9"/>
    <dbReference type="SMR" id="Q6YRC9"/>
    <dbReference type="STRING" id="262768.PAM_086"/>
    <dbReference type="EnsemblBacteria" id="BAD04171">
        <property type="protein sequence ID" value="BAD04171"/>
        <property type="gene ID" value="PAM_086"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_086"/>
    <dbReference type="eggNOG" id="COG0261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061463_3_2_14"/>
    <dbReference type="OMA" id="HRQEITR"/>
    <dbReference type="OrthoDB" id="1949059at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-115-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000270702" description="50S ribosomal protein L21">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="102" mass="11778" checksum="4153EA1544FD3FB5" modified="2007-01-09" version="2">MFAIIKTGGKQFRVFEGQEIYVEKLNVEPETTYQFQEVLAVGGSNPVLGTPFVKDAKVTAQVIKHDRAKKIIVFKYKKRKKYRCKQGHRQSYTKLLITKITV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-06-07" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRD2</accession>
    <name>SYS_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Seryl-tRNA synthetase</fullName>
            <shortName evidence="1">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">serS</name>
        <name type="ordered locus">PAM_083</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRD2"/>
    <dbReference type="SMR" id="Q6YRD2"/>
    <dbReference type="STRING" id="262768.PAM_083"/>
    <dbReference type="EnsemblBacteria" id="BAD04168">
        <property type="protein sequence ID" value="BAD04168"/>
        <property type="gene ID" value="PAM_083"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_083"/>
    <dbReference type="eggNOG" id="COG0172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023797_1_1_14"/>
    <dbReference type="OMA" id="SPCFRRE"/>
    <dbReference type="OrthoDB" id="353391at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-112-MON"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000122094" description="Serine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="232"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="263"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="350"/>
            <end position="353"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <sequence length="424" mass="48552" checksum="E59D796ADFD20DA6" modified="2004-07-05" version="1">MLDLNFVVQNLPSVIAKLEKRQQNFAYLNKLPLLAQQRKSLLLEIQDLRSQKNQSAKKVAQKANAKEDITLVLQDTNFLRDDLQKLEQKLKLKEQEIFDILSITPNLPHDSLPIGTNDKDNKELYCAGQIRTFAFTPKDHVYLAEKLDILDFKRASKISGSGFVVCKGLGARLERALIQFMMDLHNKKGYQEIIPPYIINEKSMFATGQLPKFEDEVYKLYNSKNNWYLNPTAEVPTINLHREEIFKPDTLPIKYVAYTTAFRQEAGSAGKDTRGIFRQHQFNKVELIQFCHPQNSYECLDQMLKDSEEVLKLLKLPYRVVLLSTGDLGFSMAKTYDLEVFLPSYNCYREIGSISNSCDFQARRANIKMKNPANNKNEYVHILNGSGLAVGRTVIAILENYQNQDGTITVPEVLQPYLGTDIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRD6</accession>
    <name>Q6YRD6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type polar amino acid transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">glnQ</name>
        <name evidence="3" type="ordered locus">PAM_079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_079"/>
    <dbReference type="EnsemblBacteria" id="BAD04164">
        <property type="protein sequence ID" value="BAD04164"/>
        <property type="gene ID" value="PAM_079"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_079"/>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_14"/>
    <dbReference type="OMA" id="MMEISIE"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="2">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="159" mass="18195" checksum="3FFC5AB4FD490ED1" modified="2004-07-05" version="1">MVFQNFNLFEGKTVLENCCLAPMKVLKLSKQEAQENALERLKELDLEALANQRVETLSGGQKQRVAIARVLCMKPEVILLDEPTSALDPESTLQVLQTLQKLSEKKINLIIVTHEMKFAQRVSDTIYFMEQGKILEKGTPKEIFETDKFPKSKAFFEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRE2</accession>
    <name>Q6YRE2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_073</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_073"/>
    <dbReference type="EnsemblBacteria" id="BAD04158">
        <property type="protein sequence ID" value="BAD04158"/>
        <property type="gene ID" value="PAM_073"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_073"/>
    <dbReference type="eggNOG" id="ENOG5033PU3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239554_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="255" mass="30501" checksum="142A58CA30A9E838" modified="2004-07-05" version="1">MLLRKNVKTVIFIFITITEKLKPSNLMGLLLGKRKKLRRKDLKKRSFFLEKGSKMLNNEDFYHIKQFNINTQCVDILKKLFHKSSFSLNFNEYMCHHHHLLNQYLTDNNYHSQSQKVIRGKINEYLILFYFQNQGIINLYPQAYLFFIPDIKFDLVLFTKNKRIVAFNFKTCLRDRYKQAMVEAQQLKKIDTRFEFYLLTNNTVETQRLNKKIKQGKISGINQVIDCFSPQANIFLQTLLTNQFLPFSDINMIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRF9</accession>
    <name>Q6YRF9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04141">
        <property type="protein sequence ID" value="BAD04141"/>
        <property type="gene ID" value="PAM_056"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_056"/>
    <dbReference type="HOGENOM" id="CLU_1914933_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-74-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="132" mass="15461" checksum="C71698F6E371D032" modified="2004-07-05" version="1">MEKFGKDIVKTLPHSIKTEIVKKRIKEYIKKKINQKVGHAIAKTALKKSTKKAVGSFWGKVFFPEVFEAAEAAERKYESYAYINKKIIFDITNNYYKKTIGFSVHFPSEDVIEVYELFLDNNKRSYRLIQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRG3</accession>
    <name>Q6YRG3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_052</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_052"/>
    <dbReference type="EnsemblBacteria" id="BAD04137">
        <property type="protein sequence ID" value="BAD04137"/>
        <property type="gene ID" value="PAM_052"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_052"/>
    <dbReference type="HOGENOM" id="CLU_635607_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="476" mass="57207" checksum="E889D3A3C0FC0400" modified="2004-07-05" version="1">MFEPLERIKCYKKHLKEKKEERYLSLSDDDLKLDYSLKKQLKEIKLQETKPKSKILRHYRDSSQNAKDKLLYNFKDSKKISFITLTAPYDDLKGKTIKYTHEPDIMGQVRKRFIRLVRKNYLSNLFQQFSQKDLVYSKMQDFRYFWSLETTKLGVIHYHIIFNIDVLNSFGVYSRYLCTDKDYALGLKNRPIKGNKSIFYDDYLMHKIDEKGNIKIPQNYYEKKNVKVSKITLLWANAYASVMNKNNIKHYKHLNPISQNVQIFRPSKTNLLFEKIEISKCKVFYKGTFDKKDYVNKIVSYVSKYVSKNDKQIESNSNKGIDFYSRHLFGFSRTCFSCPQESFLALFPYDIIKEIELSSFPIVNFNFSNIFEWNIKQRVNGRNIKIPHNLTLLFKSYMNPNQFQNSNYFSLNLSSIQPKNYFLNNNFKKYFKLQKLKLKLKKDYEKQDIKILNKVECQYWYRYLENNYIQSLQLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRH6</accession>
    <name>Q6YRH6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04124">
        <property type="protein sequence ID" value="BAD04124"/>
        <property type="gene ID" value="PAM_039"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_039"/>
    <dbReference type="HOGENOM" id="CLU_490771_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-55-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="555" mass="65656" checksum="E5EC2145FBD1F5B7" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRJ8</accession>
    <name>Q6YRJ8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase III delta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">holA</name>
        <name evidence="2" type="ordered locus">PAM_016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_016"/>
    <dbReference type="EnsemblBacteria" id="BAD04101">
        <property type="protein sequence ID" value="BAD04101"/>
        <property type="gene ID" value="PAM_016"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_016"/>
    <dbReference type="eggNOG" id="COG1466">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_860076_0_0_14"/>
    <dbReference type="OMA" id="DCESDPL"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-21-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010372">
        <property type="entry name" value="DNA_pol3_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06144">
        <property type="entry name" value="DNA_pol3_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_pol3_delta" evidence="1">
        <location>
            <begin position="8"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="323" mass="38376" checksum="F4CC6C32D0087991" modified="2004-07-05" version="1">MEQTNNIHLIWGKQRFFLEKKIKKIINICKQKKLDVVYYCMQKDLVTELQKELQTTSLIESAWKKVVLVDHSEILFQKKPQEMAFLISYLQNPYNNLDLYFFAEKTTKASEVQKIWEKYCLCKTTNSLEKKDFFKYIMEVFQKDGFQIDTKAIQELVSKTNYNLYLLHQEITKIKLFQSNDKNITCQLVQKINAFKENDNIFGLINLFLKQNYIDAYQMYQTLKTQKINAFHVINQLTHKIKELLLVKEMLQQKKTPEEVQKVLPVSQGKVFFLMKEAKLIETQKLNTLFLDLIELEYQIKMGAVNKDIGLEMFLLGKQKVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRK1</accession>
    <name>Q6YRK1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Replicative DNA helicase</fullName>
            <ecNumber evidence="3 11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dnaB</name>
        <name evidence="13" type="ordered locus">PAM_013</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 11"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_013"/>
    <dbReference type="EnsemblBacteria" id="BAD04098">
        <property type="protein sequence ID" value="BAD04098"/>
        <property type="gene ID" value="PAM_013"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_013"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005373_0_1_14"/>
    <dbReference type="OMA" id="IEFHARI"/>
    <dbReference type="OrthoDB" id="1709134at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-18-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0639">Primosome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="12">
        <location>
            <begin position="175"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAD04098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="447" mass="51500" checksum="8ECD3DAAF1C9A642" modified="2004-07-05" version="1">MTNYSKNTPSSPEAERALLGALLLNPEKIAFTLDMIAETDFYSSHHQHIFRAMKTLHETNKQIDYSSVSAILDNEKLLQQIGNIDYLNELSDLMPSTQHIETYIDLIKETALKREIIETVTSLAQKGYENIDVQEYLDFSEEKIFNLTKNKKTSELLKLKILLKDTKEKNILAKRHKDLVGLSTGYDNLNNITLGFKPEEFIILAARPSMGKSTFMLNLALRIANPKHNSQSPHIAIFSLEMSNEQLAMRMLSAQSKIQHKKIQLGNTNREEKFLLEISMEKMDDLNIYFDDSATVNILDIKAKCRKLKSQNKLDIVMIDYLQLIRKTNKHNRQEEVAEISQSLKQMARELKIPVIALSQLSRDVEKREDKRPILADLRDSGSIEQDADIVMFLYREGYYEKDKKPDSSGHTQVIIAKNRQGSIGIREFLLDFDHMFFSEIEPNINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-02-05" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A9JR00</accession>
    <name>A9JR00_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAF95567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_757"/>
    <dbReference type="EnsemblBacteria" id="BAF95567">
        <property type="protein sequence ID" value="BAF95567"/>
        <property type="gene ID" value="PAM_757"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_757"/>
    <dbReference type="HOGENOM" id="CLU_206667_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF95567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="47" mass="5549" checksum="F9F9926354CADDF8" modified="2008-02-05" version="1">MSDAMTETYQGTYFKDRSTTKTPKGKWLNLHHSNKTFKNKKKLSKNK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-06-07" modified="2022-08-03" version="123" xmlns="http://uniprot.org/uniprot">
    <accession>P61745</accession>
    <name>GPDA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycerol-3-phosphate dehydrogenase [NAD(P)+]</fullName>
            <ecNumber evidence="1">1.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NAD(P)H-dependent glycerol-3-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gpsA</name>
        <name type="ordered locus">PAM_241</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04326" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04326.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P61745"/>
    <dbReference type="SMR" id="P61745"/>
    <dbReference type="STRING" id="262768.PAM_241"/>
    <dbReference type="EnsemblBacteria" id="BAD04326">
        <property type="protein sequence ID" value="BAD04326"/>
        <property type="gene ID" value="PAM_241"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_241"/>
    <dbReference type="eggNOG" id="COG0240">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033449_0_2_14"/>
    <dbReference type="OMA" id="NRMFGNM"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-289-MON"/>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
        <property type="entry name" value="NAD_Glyc3P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword id="KW-1208">Phospholipid metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000138003" description="Glycerol-3-phosphate dehydrogenase [NAD(P)+]">
        <location>
            <begin position="1"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="252"/>
            <end position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="329" mass="36218" checksum="AC5D4AC43F087290" modified="2004-06-07" version="1">MKITIIGSGAWGSTLAQVLTDNNNQVLLYDINLSYVEKINQGKHPIFNAPLVNVKAVSCLKQALDYSDLIVLSVPMKFMRHLLKQIALMLTTPKSFVNVSKGIEPLTFLRVSEIVKQVIPAPLLANFASLMGPSHAEEVILRKLTLLTAASSNPAFALEIQKLFSCPNYLKVYTSSDLVGNEICSAFKNVLAFINGILVAKNFGINSQAALMSRGILEMSVLVTFYQGNPQTVLGLPGLGDLIVTAFSKYSRNFNAGAKIAAGITYQQIIDSSLQTIEGFQTLNAFYQLQLKHNLDLPIIQASYQLIFESKPFETVFATLMQRPFKSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="117" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPJ2</accession>
    <name>Q6YPJ2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation transport ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">zntA</name>
        <name evidence="7" type="ordered locus">PAM_733</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_733"/>
    <dbReference type="EnsemblBacteria" id="BAD04818">
        <property type="protein sequence ID" value="BAD04818"/>
        <property type="gene ID" value="PAM_733"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_733"/>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_6_3_14"/>
    <dbReference type="OMA" id="HLHLMET"/>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-888-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="599"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="666" mass="74018" checksum="867995BE53566D14" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPL0</accession>
    <name>Q6YPL0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_715"/>
    <dbReference type="EnsemblBacteria" id="BAD04800">
        <property type="protein sequence ID" value="BAD04800"/>
        <property type="gene ID" value="PAM_715"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_715"/>
    <dbReference type="eggNOG" id="COG0468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2918149_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="61" mass="7087" checksum="3BF7893F2A5A8D4C" modified="2004-07-05" version="1">MIEVIDLATNLNLIQKSGSWYSFKDEKIGQGTENVKKYLTNNPKIYNHLVAEIKKRYNISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPL2</accession>
    <name>Q6YPL2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="15">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">hflB</name>
        <name evidence="15" type="ordered locus">PAM_713</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_713"/>
    <dbReference type="EnsemblBacteria" id="BAD04798">
        <property type="protein sequence ID" value="BAD04798"/>
        <property type="gene ID" value="PAM_713"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_713"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_16_2_14"/>
    <dbReference type="OMA" id="HMEYDQT"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 15" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AAA" evidence="14">
        <location>
            <begin position="5"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="BAD04798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="364" mass="39813" checksum="B159F6FA138A6595" modified="2004-07-05" version="1">MGVCIPKGVLLSGPPGTGKTLLAKALAGEAGVPFYAVSGSEFVERYVGVGASRVRELFKEAKYNAPCVLFIDEIDVLGGKRGHDSRGGQEKDQTLNQLLTEMDGFTKSQGIIVVAATNRADMLDSALLRPGRFDRQFIVGLPDVKARKAILQVHARNKKIDVNIDFTSIAKQTPSMSGAQLGAVLNEASILAVRNKKNVITLEELEEAIDRVLMGPAKKSIKYNEEERKMVAYHEAGHAVIGLKLKYAQKVQKITIIPRGSSGGYNLIMPEKETFFTSDKKMLAQITSYLGGRVAEEIIFNEVSNGAYDDFRQVTKIARLMVTKYGMSSLGVSQDSEFSDKTAIDLEIKKIIAKCYTKAKEIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="120" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPM6</accession>
    <name>Q6YPM6_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_535</name>
        <name evidence="6" type="ordered locus">PAM_699</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">Onion yellows</strain>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_535"/>
    <dbReference type="EnsemblBacteria" id="BAD04620">
        <property type="protein sequence ID" value="BAD04620"/>
        <property type="gene ID" value="PAM_535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04784">
        <property type="protein sequence ID" value="BAD04784"/>
        <property type="gene ID" value="PAM_699"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_535"/>
    <dbReference type="KEGG" id="poy:PAM_699"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-641-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-851-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="104" mass="12068" checksum="137993D88AF74AE9" modified="2004-07-05" version="1">MLNKVQLIGNIAHDLEKQYINSNNEQIPKIDFNLAINNKDKVQYTPCVVFRTQAENCHKYLHKGSKIYVEGNLSIQKYKTNEGQTRTTTKVIIQNVIFLENKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPM8</accession>
    <name>Q6YPM8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04782">
        <property type="protein sequence ID" value="BAD04782"/>
        <property type="gene ID" value="PAM_697"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_697"/>
    <dbReference type="HOGENOM" id="CLU_2001523_0_0_14"/>
    <dbReference type="OMA" id="NYFLNYT"/>
    <dbReference type="OrthoDB" id="2045918at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-848-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="147" mass="17396" checksum="29606B1E15D12E99" modified="2004-07-05" version="1">MFIFTILTTITNYFLNYTKGFTTTEILERRTDAIQTTLFAILIVTGFKPVFKLIKNIIIFIKETILGLFFPNKKLQNLEIKNAKQEYREQQLIKKLDEIRDSQNKLQSQISTQNLKVAIWRDKKERKRLLKSQKHNKTSIGKDNEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPP3</accession>
    <name>Q6YPP3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04767">
        <property type="protein sequence ID" value="BAD04767"/>
        <property type="gene ID" value="PAM_682"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_682"/>
    <dbReference type="HOGENOM" id="CLU_1319854_0_0_14"/>
    <dbReference type="OMA" id="PNTRIYP"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-833-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="192" mass="23002" checksum="8CEF3F2ECB2A3D65" modified="2004-07-05" version="1">MCVKWGAFRFLQILKGELLNITIVSHSKKKNSYQQANYRPKNQTLFVDPQILDEMKKYRIEIIKTHSPENNNNNQTLTNPISPPKCQNNTLKTHFPIFQINYLNEQKDYIKELISKIPIDKLDTLKLYKLDDKKVDKYNNPIKTNYKKGLNVIYYQLEDLKHIKLFLTKNKQGYRVKKMRPDYKRYLTKEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPR2</accession>
    <name>Q6YPR2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04748">
        <property type="protein sequence ID" value="BAD04748"/>
        <property type="gene ID" value="PAM_663"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_663"/>
    <dbReference type="HOGENOM" id="CLU_823468_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="337" mass="39847" checksum="D27276E1A74D6D97" modified="2004-07-05" version="1">MNNLEQPKHFLLAKVCLLLLALWIFIVLLGNIITVWANNPLKENLANGVIEKRKYLEESTQDNKLVDWQNPDTYDAIYDTNGNQIAQRHYKLESTQDNKVVDWTHYNVWDATYDKNGRQTSKRYFLAQSTENNKLVDWQNPDTWDATYDKNGRQTSKRYFLAQSTENNKLVNCKHHDTWDKTYDKNGNQLLERHYLQGSTEKDKLVDWKNNDTWDATYDANQKQISKRHYLETSTENNKVVDWQHYDTWDATYDKNGRQTSQRHYLETSTENNKVVDWQHRYTWGKSSNVEPILPITNVLVDKNTQKNKVYLPHTNNKVADVGDLKSQTYDTHTFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPR4</accession>
    <name>Q6YPR4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type spermidine/putrescine transport system, permease component II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">potC</name>
        <name evidence="7" type="ordered locus">PAM_661</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_661"/>
    <dbReference type="EnsemblBacteria" id="BAD04746">
        <property type="protein sequence ID" value="BAD04746"/>
        <property type="gene ID" value="PAM_661"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_661"/>
    <dbReference type="eggNOG" id="COG1177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_3_0_14"/>
    <dbReference type="OMA" id="FPMFVWG"/>
    <dbReference type="OrthoDB" id="1264541at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-806-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="85"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="294"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="334" mass="36989" checksum="08F563F1395A3065" modified="2004-07-05" version="1">MSIKLSRATPPQTASTKIPKKPKKTITNTLYIILVLSFIYIPILSLIIFSFNKSEGRIASLVNWQGFSFEWYSKLWTDQTVKTAIKITLYIACLTTLISTFLGTFAAISLAQSLNKKWRNIVLNVSNFSIVIPEIITALALFVVFGFMGLESGFWKMLLAHISFCTPFVVITVYPKVINLDPHSLEAAYDLGATPLKALTKVILPQLKGAMLLGATLAFSLSFDDFMISYFVGGSECQNISAYIYSLKGTINPTVNALSTILIIIASSKIILNFIKYNNQKQNQRKNAKIEAEANNNENESINGATTITTNKTTTTNTKTSAKTNTNENEFNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPT5</accession>
    <name>Q6YPT5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PBPb domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">PAM_640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_640"/>
    <dbReference type="EnsemblBacteria" id="BAD04725">
        <property type="protein sequence ID" value="BAD04725"/>
        <property type="gene ID" value="PAM_640"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_640"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1041475_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-780-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="29"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="267" mass="31427" checksum="02D82B83850A2DAD" modified="2004-07-05" version="1">MLLIQIFLGKGYIKKLLNNRDIIKKETSSDDIGPNLEFIRNNKADIFVVDDVIAHYNTEGDKDLKYFILDSTDPQLQSGPNGVGVVVKKGDTKRQKEVNDALRKIFNLEYVKDKDGKDTDVIEDLKYILTRLHELKKEKRTKDQETRYKDLKGKNKRKPEEEKEFSTLFKVLDKFILGNLQKIDEAQERFDALKEIKLEFDTLEKCLDGKRKEIKEEHDQLKNKKAYNSKTQKNNQNLNQRTQEEQKFRVLKNVPLLLKMIQKKKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPT9</accession>
    <name>Q6YPT9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized BCR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">degV</name>
        <name evidence="2" type="ordered locus">PAM_636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_636"/>
    <dbReference type="EnsemblBacteria" id="BAD04721">
        <property type="protein sequence ID" value="BAD04721"/>
        <property type="gene ID" value="PAM_636"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_636"/>
    <dbReference type="eggNOG" id="COG1307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048251_3_1_14"/>
    <dbReference type="OMA" id="HCENEAD"/>
    <dbReference type="OrthoDB" id="1288126at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-777-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="287" mass="32624" checksum="0950BBE307247DDF" modified="2004-07-05" version="1">MKIKVATTSTSCLDYYSHSCDIDIFRIKILIDDQEYIDGKTMKYDQFYQMFKNNPDFMPKTSQVSVGEMVVYFEKLALQGYQKVFVTTLSSALSGTYNAIIQAGKMVSDKIEVHCYDTKTVCFCEGFFALEAYRLFAEGKSLEQVVKHLDFIKENNTIFFMTKKLTQLIKNGRLVGVKSSLGRLLRINPILQVQRDGKIALIKKTLSSHKALLAITSKIKEYTQNHDYQIHLIFTGHPELKNEFQQVLETQLGLKNLVQIPLTPVVGCHVGDSAIGVGIIRKPKFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPU1</accession>
    <name>Q6YPU1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_634"/>
    <dbReference type="EnsemblBacteria" id="BAD04719">
        <property type="protein sequence ID" value="BAD04719"/>
        <property type="gene ID" value="PAM_634"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_634"/>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044146_7_0_14"/>
    <dbReference type="OMA" id="FMELGIN"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-772-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="268" mass="30788" checksum="6F759BBBF3420954" modified="2004-07-05" version="1">MKKLIFFDIDGTLRSNKNKAILPQTKALIKELSQNPNVVLGIATGRSYSRLGVLKELRPLFKYLVLCNGAITIQAQKTQEEKVLNEVCFDQKDVMQVKKAAATNGVALTLFTLDQIFAIDLQNDQTLNNINSFKGEQKLVLNDAFFEQQKVYQMVLLHEKENDKEKIQKFLKDMPQLKAYFWDSGFVDIMYQKIDKSYGIKQIKALYPDHQLICMGDGPNDFEMLKLADVAITMGNTKIEDLKNIANFVSPHIDEDRMYDFFKTKKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPU6</accession>
    <name>Q6YPU6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_629</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_629"/>
    <dbReference type="EnsemblBacteria" id="BAD04714">
        <property type="protein sequence ID" value="BAD04714"/>
        <property type="gene ID" value="PAM_629"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_629"/>
    <dbReference type="eggNOG" id="COG2384">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071037_2_2_14"/>
    <dbReference type="OMA" id="ICGMGTY"/>
    <dbReference type="OrthoDB" id="1627266at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-765-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="147" mass="16984" checksum="F7EBBFDFBE785AFB" modified="2004-07-05" version="1">MKRIPFIASLTKNYDTVVDIGTDHGLVLKKAFQQGYIKQAIAADIKLKPLFQAQKNLACYPVTFCLSDGFQNICQDFDLALICGMGTYAITKILEKSPDKSKHFILGSQSNQDYLQEWLLKNDFQILEEYHLFDKFFYHFLKVTRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="126" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPU9</accession>
    <name>Q6YPU9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycyl-tRNA synthetase</fullName>
            <shortName evidence="7">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GRS1</name>
        <name evidence="7" type="synonym">glyQS</name>
        <name evidence="9" type="ordered locus">PAM_626</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of glycine to tRNA(Gly).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="7"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_626"/>
    <dbReference type="EnsemblBacteria" id="BAD04711">
        <property type="protein sequence ID" value="BAD04711"/>
        <property type="gene ID" value="PAM_626"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_626"/>
    <dbReference type="eggNOG" id="COG0423">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015515_2_0_14"/>
    <dbReference type="OMA" id="EPSYGID"/>
    <dbReference type="OrthoDB" id="626850at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-762-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00253_B">
        <property type="entry name" value="Gly_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
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        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022961">
        <property type="entry name" value="Gly_tRNA_ligase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="PTHR10745"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="94"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="210"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="319"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="195"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="205"/>
            <end position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="279"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="323"/>
            <end position="326"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="452" mass="52767" checksum="2686984696951D9A" modified="2004-07-05" version="1">MQHLDKVISLAKQTGFVFAGSEIYGGLANSWDYGPLGSLLKNNIKKAWLQKFVQEQPNNVLLDGSILLNSTVWKASGHLDSFSDPLTENQDTNKRFRADKLIESHNPQLDISGWSYEQMHDYLVKNQVLGTSNWTPIRPFNMLFKTHQGVILENSKPLYLRPETAQGIFIQFKNILKTTRKKLPFGVCQIGKVFRNEVTPGNFIFRTCEFEQMELEFFCQPGTEAHWFKHWKNLMYDFLITLGMNPQNLTFKDHKKENLSHYSQQTCDILFKFPWGFDELWGIASRTNFDLKTHQQHSKKDLTYFDETTKQKILPYVIEPSLGIERLFFAFLINNYHEESTSNETRQILTFHPFLAPYKVAVLPLIKKTHSAKAQEIHQYLAKHFDVCYDETQSIGKRYRRQDMIGTPFCLTVDDQTLTHNTVTLRNRDTTQQQTFLLAEAKKYIQEKIILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPV7</accession>
    <name>Q6YPV7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Restriction enzymes type I helicase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hsdR</name>
        <name evidence="2" type="ordered locus">PAM_618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_618"/>
    <dbReference type="REBASE" id="7521">
        <property type="entry name" value="PhsOYORF619P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04703">
        <property type="protein sequence ID" value="BAD04703"/>
        <property type="gene ID" value="PAM_618"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_618"/>
    <dbReference type="eggNOG" id="COG0610">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1371007_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWI2_SNF2" evidence="1">
        <location>
            <begin position="9"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="199" mass="23893" checksum="2E48711FEA280CF4" modified="2004-07-05" version="1">MKKFISINETQKNIIVFFIVDRIELDLQTLQEFNSFEKVSTQEILKVENLKEIMQNKNNASGKIIVTNLKKIHSLIKKYKNEDFLKKYKNEKMFFIIDECHRSQQGEMHENMIKYFYGSYFFGFTGTPIFEKNKLSKNAKTTKELFNKCIHEYRFSNALKDKFVIDYNVEYYRKTKNNSTCKEEVVKKILNSYHDLHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPW0</accession>
    <name>Q6YPW0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized BCR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_615"/>
    <dbReference type="EnsemblBacteria" id="BAD04700">
        <property type="protein sequence ID" value="BAD04700"/>
        <property type="gene ID" value="PAM_615"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_615"/>
    <dbReference type="eggNOG" id="COG0718">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2771836_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="69" mass="8141" checksum="ECDCCE699563E1B9" modified="2004-07-05" version="1">MKTQSNMFEKLKKMQEAIENAQKQLELQEFIGKAGDVEIVFTRHQTSRRCYYFSNSQQSNSPRKCFVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPW3</accession>
    <name>Q6YPW3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphatidylserine decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">psd</name>
        <name evidence="6" type="ordered locus">PAM_612</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_612"/>
    <dbReference type="EnsemblBacteria" id="BAD04697">
        <property type="protein sequence ID" value="BAD04697"/>
        <property type="gene ID" value="PAM_612"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_612"/>
    <dbReference type="eggNOG" id="COG0688">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029061_2_2_14"/>
    <dbReference type="OMA" id="AFISPCE"/>
    <dbReference type="OrthoDB" id="891720at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-738-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PTHR10067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0865">Zymogen</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="295"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="332" mass="38788" checksum="7FFD1DAE18E2CCA3" modified="2004-07-05" version="1">MKIVNLEGKIICQDPASRLQKFLYTNLEKNFWKRCLLKILITKPISWLVNLYFYSPWSRQYALKIIEQHQIDLNLFEKQKFSSYNDFFTRKYKELAIPQDNFAFISPCESKLSIYPITKKALYCIKETNYSLVDLLQNPTLAQEYEEGYLLIFRLEPHDYHRYLFVDEGFFQMIPCKIKGKLHTVNPIAFESFDVFKTNTREYSILQTKNFGKIVQIEVGATLVGKIQNHPLQTFSKGQEKGYFDTGGSTIIILVKKNIVSFDPRILEHTQKRYETQIPILTVIGKKITPTKPHPITYKSFSEPITPQPKSNQNSNCTTQANHKESEVQTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-12-02" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPW6</accession>
    <name>Q6YPW6_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DnaB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_609"/>
    <dbReference type="EnsemblBacteria" id="BAD04694">
        <property type="protein sequence ID" value="BAD04694"/>
        <property type="gene ID" value="PAM_609"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_609"/>
    <dbReference type="eggNOG" id="COG3935">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091656_1_0_14"/>
    <dbReference type="OMA" id="DQEFSHE"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034829">
        <property type="entry name" value="DnaD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006343">
        <property type="entry name" value="DnaD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07261">
        <property type="entry name" value="DnaB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158499">
        <property type="entry name" value="SSF158499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DnaB_2" evidence="1">
        <location>
            <begin position="147"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="227" mass="26709" checksum="666B551FC0DF3005" modified="2004-07-05" version="1">MPNPKTYSTTKAAKKRSFNNNMVMFQKLYEDGFLQVEKMLIQEYQKLGLTYPELTILLFLLDFSKKRVFSSNALAKKAGITKKEVEHILEQLMSKDFFDLSQETKNHKIIEVFSLHPTFAKLEKIYQDQIRESKRQNQLTLIQQTIEYLEHNKGQTLTSNELDLVRNWYQDQEFSHEEIKNTIEEALCVKKTSVFYINTLLGKKKFLTVIPDEKADKALAKLFKKIK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-09-22" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPW8</accession>
    <name>PLSX_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate acyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.274</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Acyl-ACP phosphotransacylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Acyl-[acyl-carrier-protein]--phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Phosphate-acyl-ACP acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">plsX</name>
        <name type="synonym">pam607</name>
        <name type="ordered locus">PAM_607</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a fatty acyl-[ACP] + phosphate = an acyl phosphate + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.274"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Probably interacts with PlsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Associated with the membrane possibly through PlsY.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PlsX family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.274" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPW8"/>
    <dbReference type="SMR" id="Q6YPW8"/>
    <dbReference type="STRING" id="262768.PAM_607"/>
    <dbReference type="EnsemblBacteria" id="BAD04692">
        <property type="protein sequence ID" value="BAD04692"/>
        <property type="gene ID" value="PAM_607"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_607"/>
    <dbReference type="eggNOG" id="COG0416">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039379_1_1_14"/>
    <dbReference type="OMA" id="HGKSNAR"/>
    <dbReference type="OrthoDB" id="631784at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-733-MON"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043811">
        <property type="term" value="F:phosphate:acyl-[acyl carrier protein] acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00019">
        <property type="entry name" value="PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003664">
        <property type="entry name" value="FA_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012281">
        <property type="entry name" value="Phospholipid_synth_PlsX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30100">
        <property type="entry name" value="PTHR30100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02504">
        <property type="entry name" value="FA_synthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002465">
        <property type="entry name" value="Phsphlp_syn_PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00182">
        <property type="entry name" value="plsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword id="KW-1208">Phospholipid metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000201894" description="Phosphate acyltransferase">
        <location>
            <begin position="1"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="339"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="366" mass="40424" checksum="4B8AFDC74191A0AE" modified="2004-07-05" version="1">MIKIAIDVMGGDFAPLEIVKGTLLALNKNKEIHVVLYGNQKLITPLIEKTPFFGNNQITIKHTPYFLRSADKNIRDQLKATPNASLFLALEAAKQDEVQGVVSAGATQTLVLASHLILKKMPLMQRIAIAPMFNSFDNRTRILLDAGANTELKPQHLHTFANYATIIAKEILEIPNPQIKLLNIGTEPTKGRALELETYQLLSQDSNLNFGGNEEPQNLLTTSADILLSDGFTANIALKTYEGTMLNFMNHFKTILTKNLIKKMATKTLFQKPLQQLKNQLDPRQIGGAMLLGLNKIVIKAHGSSQAYAFCQAILQAQKLIKAQVNQKIAHSLESAKNKETQSKQASTKNTAPKTSETTKESQQSL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-04-18" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPX7</accession>
    <name>SYFB_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="1">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="1">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pheT</name>
        <name type="ordered locus">PAM_598</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks the conserved glutamate residue in position 500 that binds magnesium; it is replaced by a serine residue.</text>
    </comment>
    <comment type="sequence caution" evidence="3">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04683" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04683.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPX7"/>
    <dbReference type="SMR" id="Q6YPX7"/>
    <dbReference type="STRING" id="262768.PAM_598"/>
    <dbReference type="EnsemblBacteria" id="BAD04683">
        <property type="protein sequence ID" value="BAD04683"/>
        <property type="gene ID" value="PAM_598"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_598"/>
    <dbReference type="eggNOG" id="COG0072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016891_0_0_14"/>
    <dbReference type="OMA" id="ISYNWLK"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_0000232816" description="Phenylalanine--tRNA ligase beta subunit">
        <location>
            <begin position="1"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-binding" evidence="1">
        <location>
            <begin position="44"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="B5" evidence="1">
        <location>
            <begin position="430"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="1">
        <location>
            <begin position="730"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>shared with alpha subunit</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="497"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>shared with alpha subunit</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="501"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>shared with alpha subunit</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="822" mass="93152" checksum="89D065A98DD906A1" modified="2006-04-18" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPY1</accession>
    <name>Q6YPY1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">asnB</name>
        <name evidence="9" type="ordered locus">PAM_594</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_594"/>
    <dbReference type="EnsemblBacteria" id="BAD04679">
        <property type="protein sequence ID" value="BAD04679"/>
        <property type="gene ID" value="PAM_594"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_594"/>
    <dbReference type="eggNOG" id="COG0367">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014658_2_2_14"/>
    <dbReference type="OMA" id="DWSGIYS"/>
    <dbReference type="OrthoDB" id="610569at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-719-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="347"/>
            <end position="348"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="558" mass="63686" checksum="425D54389A0E8B43" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPY5</accession>
    <name>Q6YPY5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04675">
        <property type="protein sequence ID" value="BAD04675"/>
        <property type="gene ID" value="PAM_590"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_590"/>
    <dbReference type="HOGENOM" id="CLU_2047295_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="120" mass="14292" checksum="EA5E594606B5162B" modified="2004-07-05" version="1">MCSLQNLKKPFCLKNAPKKLIYVYQKDIDLSKYGYGNNTHSIEDLKNSRLGIKNLYLFWLKDGSQAEPKQRDAIINSSSSRTRQKNWDGSPNLQNWQSQNWEDELEENWEKEFQTDWEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPZ1</accession>
    <name>Q6YPZ1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Diadenylate cyclase</fullName>
            <shortName evidence="10">DAC</shortName>
            <ecNumber evidence="10">2.7.7.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cyclic-di-AMP synthase</fullName>
            <shortName evidence="10">c-di-AMP synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dacA</name>
        <name evidence="12" type="ordered locus">PAM_584</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably a homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the adenylate cyclase family. DacA/CdaA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.85" evidence="10"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_584"/>
    <dbReference type="EnsemblBacteria" id="BAD04669">
        <property type="protein sequence ID" value="BAD04669"/>
        <property type="gene ID" value="PAM_584"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_584"/>
    <dbReference type="eggNOG" id="COG1624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038561_1_0_14"/>
    <dbReference type="OMA" id="YLAIFMN"/>
    <dbReference type="OrthoDB" id="1300262at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-707-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019932">
        <property type="term" value="P:second-messenger-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01499">
        <property type="entry name" value="DacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014046">
        <property type="entry name" value="C-di-AMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034701">
        <property type="entry name" value="CdaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004793">
        <property type="entry name" value="UCP004793"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="DAC" evidence="11">
        <location>
            <begin position="92"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="263" mass="30050" checksum="AC3B060117D5D806" modified="2004-07-05" version="1">MKGISMFGTSPLWTVFLFLCIFIVFHFFLRKYQVLNMVFLFLLLFSLVYCLKSYHDTFVEPIFKRYLSLDISENIYDCLLNFILTSIIIIKAPYLRVAFNNWSKHWNIKRQNFFMGGDNTQKEIIKATLELASRKIGALITIEKNNTLEQYAQKAILIDGNVSKELLLNIFALNTPLHDGAVIIRGDKILCASAYFTLSSSADSLDKKTGSRHRAALGISETTDSMTIVVSEETGNISIALEGMMFQTNEQEKLKEYLAIFMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPZ3</accession>
    <name>Q6YPZ3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04667">
        <property type="protein sequence ID" value="BAD04667"/>
        <property type="gene ID" value="PAM_582"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_582"/>
    <dbReference type="HOGENOM" id="CLU_1371006_0_0_14"/>
    <dbReference type="OMA" id="IEDWHKL"/>
    <dbReference type="OrthoDB" id="1408987at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-705-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="199" mass="23462" checksum="92953B613CFC397D" modified="2004-07-05" version="1">MSMFYQRKKLFFKILLVLVLIFFITTIAYAIEDWHKLKKDSNFGLKIAAPAELSVSKPADLHDTNKKFLVPTEHSFLMTTEQTDRVIFEQEATLKTQNDKLTFINGKNTKLDINYFFENLDLNEQLKDFFNVQILWKYKEQPQQSFVSYDNENKPVIIDKNGNLKKIIVQFTIYASKVFPSGFQTKEKQLQIKYNIQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ05</accession>
    <name>Q6YQ05_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replicative DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dnaB</name>
        <name evidence="2" type="ordered locus">PAM_570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_570"/>
    <dbReference type="EnsemblBacteria" id="BAD04655">
        <property type="protein sequence ID" value="BAD04655"/>
        <property type="gene ID" value="PAM_570"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_570"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_546093_0_0_14"/>
    <dbReference type="OrthoDB" id="1709134at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-688-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="1">
        <location>
            <begin position="190"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="498" mass="58768" checksum="207D67E5D284FCE2" modified="2004-07-05" version="1">MLTNEQKALKKLINYIEQGQWEKLNLYYQIINPKNLLNPKNKKIFTTLKYLFLEKQTTHPWDKIKSQTEIIKELLTYLQTNFQQDNFTKESLSFLNNDFSKENNLDFLDNLKHTYTQEKLFQQLLKIISPSFETQDPYTKNLYYHKIFDKLRNFISLIPQKNDKTLFNLNQMVFLHPEFFDTDNQAKQKIQEEYYHLSEIFKGLNQSTKGLKKGQIITIGGYTGLGKTTFVYNLLLDIAKTKHQESSHYPHILVFSYEMTMEENLSRLLAHQTQIPLDIILDKNFEDDNITPLKYTERMKIAKQFFANINLSFSYDKSKILIISLILVYRLYLEKQVEIIVIDHLQITKASNRLENDRLAIDEIMTKLKQLAMELNIVIIILSQFSRDTYSNYQGKSPEITALKGSGGIETNSDIVLMMSEFQPKLSKDKEKPLNIYNSTLNQLYLESDDNENQKIIEVCIKKNRSGTKKTLIYHFEMTTQTFQEIGYVLPYQIETYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ15</accession>
    <name>Q6YQ15_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_560"/>
    <dbReference type="EnsemblBacteria" id="BAD04645">
        <property type="protein sequence ID" value="BAD04645"/>
        <property type="gene ID" value="PAM_560"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_560"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145374_0_0_14"/>
    <dbReference type="OMA" id="MNSHQFQ"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="149" mass="18118" checksum="B499129360D19257" modified="2004-07-05" version="1">MFGFSRTCFSCPQESFLALFPYDIIKEIELSSFPIVNFNFSNIFEWNIKQRVNGRNIKIPHNLTLLFKSYMNSHQFQNSNYFSLNLSSIQPKNYFLNKNFKKYFKLQKLKLKLKKDYEKQDIKILNKVECQYWYRYLENNYIQSLQLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ21</accession>
    <name>Q6YQ21_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_554</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04639">
        <property type="protein sequence ID" value="BAD04639"/>
        <property type="gene ID" value="PAM_554"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_554"/>
    <dbReference type="eggNOG" id="COG2849">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1413920_0_0_14"/>
    <dbReference type="OMA" id="IHINLPD"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="192" mass="22383" checksum="106D4CB01436754A" modified="2004-07-05" version="1">MENNIIEEPKLIKLGCYNATPHAGLVLSLPSKTFHEIDIDTIYFDDGIRIIEPQQGNIQDLLKLSNGAKNIYLLIFNTIKRAIHINLPDSLNPYKDIRDWKRANNLYNYEGEYNRASKSGNNPITITKPTYKEINISYAINLLENTFETEDKIYRITCQDTKPKRDILMDYQKDYIAWLNQCYIKYGCTYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ32</accession>
    <name>Q6YQ32_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YqaJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04628">
        <property type="protein sequence ID" value="BAD04628"/>
        <property type="gene ID" value="PAM_543"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_543"/>
    <dbReference type="eggNOG" id="COG5377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1209247_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017482">
        <property type="entry name" value="Phage_endonuclease_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03033">
        <property type="entry name" value="phage_rel_nuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ" evidence="1">
        <location>
            <begin position="16"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="216" mass="25714" checksum="DD614B8974E9F639" modified="2004-07-05" version="1">MNIMRIKNLNQRTKLWYQHRKKYINASEIASITGLDPFRSMEQLVLDKLFGTTFTANQYTLHGQKMEPIARQFFIQKTNLIFEDTIFTDDQVNLFSASLDGYNEQHQAVLEIKCPYVNENQEVSTTWTHFLTHPQLENIPQYYWAQVQCQLYCSQAQFAYFLVYFNDQNYHVVRIYPDKTFITKMIQDSQKYLALLTKAKDELEKTTYLKQLSKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ33</accession>
    <name>Q6YQ33_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_542</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_542"/>
    <dbReference type="EnsemblBacteria" id="BAD04627">
        <property type="protein sequence ID" value="BAD04627"/>
        <property type="gene ID" value="PAM_542"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_542"/>
    <dbReference type="HOGENOM" id="CLU_1439732_0_0_14"/>
    <dbReference type="OMA" id="NIQIRID"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="188" mass="22409" checksum="96284C925BF1A91B" modified="2004-07-05" version="1">MIKLQNQFKIISIYLFTFLGLLFITNNYQVMAMDNNDGISENNSVVDNHIDEYNTFRNLLLTQGRISQQLINALFNHSSVTEINFLLNQIQQVHQQIITYQQRQLNNQEQMLRNFDNNMTIVQLEREYLLLTQEMISAINNTPLYASEEQINTLRNIQTRIDQNQRQINIIRNQIQNNQNQPNNHRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ43</accession>
    <name>Q6YQ43_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">PAM_532</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_532"/>
    <dbReference type="EnsemblBacteria" id="BAD04617">
        <property type="protein sequence ID" value="BAD04617"/>
        <property type="gene ID" value="PAM_532"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_532"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="OMA" id="NGSDIYH"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-636-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="5">
        <location>
            <begin position="322"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="102"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="537" mass="62908" checksum="E3B5F90AD1C10E1D" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ49</accession>
    <name>Q6YQ49_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_526"/>
    <dbReference type="EnsemblBacteria" id="BAD04611">
        <property type="protein sequence ID" value="BAD04611"/>
        <property type="gene ID" value="PAM_526"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_526"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_21_0_14"/>
    <dbReference type="OMA" id="CRIHEYL"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_21" evidence="1">
        <location>
            <begin position="50"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="152" mass="18615" checksum="C7F14BFF19042CB9" modified="2004-07-05" version="1">MVFYLVNQFNPNLDLTTILKTIQIKRSTYYYWLKIKDKLKEKEEKYFLQEKRIEALCLHHQYFYGHRKITDLYQKTFNEFITKKKVYLIMKKNNICCCLRPKKNFTYRNLTNNLQIIPNLINQDFMATKPLQKIFTDITYFKTNQGFFVGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ58</accession>
    <name>Q6YQ58_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_517"/>
    <dbReference type="EnsemblBacteria" id="BAD04602">
        <property type="protein sequence ID" value="BAD04602"/>
        <property type="gene ID" value="PAM_517"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_517"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1137139_0_0_14"/>
    <dbReference type="OrthoDB" id="1779749at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-620-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="244" mass="28991" checksum="24D60019D9711DC2" modified="2004-07-05" version="1">MFNIIKKTIKWIFIILGVLLFLLIGWIVLTEMNIIKLPKEEIPILKETKADIKKEWDETDHKGRIQPMIEIHYTFDGLNGIGYYQQQFQAKKGSHHNILTAQERIESQPEPTNLASYIKDRHPFDRWNKDGDTYNHTTFNGFNSAHFYTKDDSYLDNYVNFEKHEHKGPGYNKLILKYKGPKHFLEDDKDYYLGRAFVHNSNFKLTNFHLHFNPVRKTLSLYQDKHNYDKVKEVKNGKNQPGWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ59</accession>
    <name>Q6YQ59_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome segregation ATPase homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">smc</name>
        <name evidence="2" type="ordered locus">PAM_516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_516"/>
    <dbReference type="EnsemblBacteria" id="BAD04601">
        <property type="protein sequence ID" value="BAD04601"/>
        <property type="gene ID" value="PAM_516"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_516"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2118571_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-619-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="114" mass="13457" checksum="E49CEB41ADF50421" modified="2004-07-05" version="1">MQQGLHIEALEGTIKALENASSKYIEENAELRHEINKLKEQLKDEQKSHEATKVTLKEKSDKLTRETEVYTHLKETIDNQKTWKGSLQPVKDKIIDYANKTVDKVTSWFKRRWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ73</accession>
    <name>Q6YQ73_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_502</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04587">
        <property type="protein sequence ID" value="BAD04587"/>
        <property type="gene ID" value="PAM_502"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_502"/>
    <dbReference type="HOGENOM" id="CLU_563640_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-605-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="484" mass="56948" checksum="BB29EEED611B3B48" modified="2004-07-05" version="1">MDNAKRKKSFYLKVSKLYLLISLLFFILNITYVFATTNNETQTYTSSSRAYKPHNEGEEKQLDWENPNTWDKVYDSNNKQISKRYFKEGSDEDNKQVNWDHDKTWDKTYYDGNFAEEVQAEEYILTERHYTSNSKEYKKIVNWNHDKTYDIELKIINNRPYKLNKRSYLNDNKEINWKSPNTWNRTLDDNSGHTLEQRHFKTSEDDIYWEHKETWNKEYQDNEMTKQTFFNSDGSEKTTSYSSSSEDDDSSMNVDLADGDASMDVNSEDDGGFVPLYSFGNKDDNVVITFVDDSKKEVLEQDENNNIKKQIRYTIEDDKKVDWENDETYDAEYDENNIKISETHYLRDSENEDEQKPIDYKKSWFFIPKSATTTIEETIEEGNPTVTLITVNNLITKKTTKTTIVGDEVRQSEITKEEDETTEVDKKDETTAENNEPVVPANTQSPEKEPQTKLTPKIVMGVLVTTIVVSLIYVYVKREQLFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ79</accession>
    <name>Q6YQ79_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_496"/>
    <dbReference type="EnsemblBacteria" id="BAD04581">
        <property type="protein sequence ID" value="BAD04581"/>
        <property type="gene ID" value="PAM_496"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_496"/>
    <dbReference type="HOGENOM" id="CLU_2181186_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-599-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="109" mass="13302" checksum="175BE19D23E7BBFE" modified="2004-07-05" version="1">MQLDNNKINDNIDLNLEQHLDKKNTWLQIIENKNSNSFHSISEIRIKHVFKYFYQKIMDEQRVYQIRINNIERIFFFIDEKGVCCPIGYDKFHFLYSMKTNPKKLILTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ95</accession>
    <name>Q6YQ95_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hflB</name>
        <name evidence="2" type="ordered locus">PAM_480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_480"/>
    <dbReference type="EnsemblBacteria" id="BAD04565">
        <property type="protein sequence ID" value="BAD04565"/>
        <property type="gene ID" value="PAM_480"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_480"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_791878_0_0_14"/>
    <dbReference type="OMA" id="IEYFMAT"/>
    <dbReference type="OrthoDB" id="1925342at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-565-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="65"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="350" mass="39526" checksum="8C21375AC5D01DF9" modified="2004-07-05" version="1">MNSDSLSGLLDVLTPPEFNFENFKPYSCIFGLEEPIQKLKEIGDLFDLITKHKYNLGKKGKPTHTLEEIEKIFAKARKNSSSIVFADEAEETIKARDSKDFLEPGDAKKPLLISAELDGVKTDPDKPICFVVATNHLGKIDSAIVSRLEPVYIGNIESDRRIGFLRLMAKLYKINQNTYDYLKVIADNFNYSLDHPEMFAEAIEHGYVIPAVAKKSFRGSIKIGAIEYFMATLDPVNNVVDRNERLEKMKKAGAQYLPPTDQNGKPKYDIEVLEGIKKHFFDLLSGRKLENLITNAANKAGFHGHSEILISDLEEACGEYFGHRQDYLNNNNLSQEAKEALEKINNSLYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQA8</accession>
    <name>Q6YQA8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NifU homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">iscU</name>
        <name evidence="2" type="ordered locus">PAM_467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_467"/>
    <dbReference type="EnsemblBacteria" id="BAD04552">
        <property type="protein sequence ID" value="BAD04552"/>
        <property type="gene ID" value="PAM_467"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_467"/>
    <dbReference type="eggNOG" id="COG0822">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079283_4_1_14"/>
    <dbReference type="OMA" id="MKLDSMY"/>
    <dbReference type="OrthoDB" id="1793654at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-552-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="8"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="147" mass="17088" checksum="7CDBC732016759DB" modified="2004-07-05" version="1">MLEINKLYRDLIIKHYQEPQNWGLSQDPDFINITNKNVSCGDSISLQIKISNQKLIDIKYETQACAICRASASLMSIHLKNLEIQQTLEKINHFLAMINNQIYDETQLDKELLLFKHFINFPGRVACISLPWKALQQVIKAHNKKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQB1</accession>
    <name>Q6YQB1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type amino acid transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">artM</name>
        <name evidence="7" type="ordered locus">PAM_464</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_464"/>
    <dbReference type="EnsemblBacteria" id="BAD04549">
        <property type="protein sequence ID" value="BAD04549"/>
        <property type="gene ID" value="PAM_464"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_464"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1957346_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="128" mass="14172" checksum="EF6D62EF25726072" modified="2004-07-05" version="1">MAIDGLFLGFLLVILCTLMKNAQSNNPYILKISKGINWIFDILFFILKTMPTAAQAMLVYYGIGKLCNKGVITSLNAGLLVLILNSLANINVILMQNIKFLDKGQIEAALSLGMSQRQVFSLLFFPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="108" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQC0</accession>
    <name>Q6YQC0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">argS</name>
        <name evidence="12" type="ordered locus">PAM_455</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_455"/>
    <dbReference type="EnsemblBacteria" id="BAD04540">
        <property type="protein sequence ID" value="BAD04540"/>
        <property type="gene ID" value="PAM_455"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_455"/>
    <dbReference type="eggNOG" id="COG0018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006406_6_1_14"/>
    <dbReference type="OMA" id="YEFKWER"/>
    <dbReference type="OrthoDB" id="1146366at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-539-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="11">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="10">
        <location>
            <begin position="443"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="557" mass="64906" checksum="9B9334DB8BD1A9A7" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQC9</accession>
    <name>Q6YQC9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04531">
        <property type="protein sequence ID" value="BAD04531"/>
        <property type="gene ID" value="PAM_446"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_446"/>
    <dbReference type="HOGENOM" id="CLU_1873325_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-526-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="136" mass="16075" checksum="498DF8CFF536D421" modified="2004-07-05" version="1">MFRIKFIIFKPELDKQGRKQIDFWKTQIRNIFNFLFFLVILLSSGFISFHIDSILKQNTTLHPLMKNFLIMMKLFFWICSLLSLPFVFCSFFLMGVDSMKGRTFSQFILSKIYSKPQIAPNGKNNQSKNNTNTPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQD1</accession>
    <name>Q6YQD1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription termination factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nusB</name>
        <name evidence="7" type="ordered locus">PAM_443</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NusB family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_443"/>
    <dbReference type="EnsemblBacteria" id="BAD04528">
        <property type="protein sequence ID" value="BAD04528"/>
        <property type="gene ID" value="PAM_443"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_443"/>
    <dbReference type="eggNOG" id="COG0781">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087843_3_3_14"/>
    <dbReference type="OMA" id="TKQFCNL"/>
    <dbReference type="OrthoDB" id="1574817at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-523-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="6">
        <location>
            <begin position="28"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="149" mass="18121" checksum="F193417A83437897" modified="2004-07-05" version="1">MKHTQNKKESRLLRIEVMKLLYQYDFYQNNLTLSQTNPNPIFTFFQKIITNLKFIDEIITKSLYDYKINRLNKVDRAIIRLATYELLETNISHAIIIDEAIELTKQFCNLNDEKQHKFNNKLLDQIYQQLQMYKKTYYLIELKNYPNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQD7</accession>
    <name>Q6YQD7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_437"/>
    <dbReference type="EnsemblBacteria" id="BAD04522">
        <property type="protein sequence ID" value="BAD04522"/>
        <property type="gene ID" value="PAM_437"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_437"/>
    <dbReference type="eggNOG" id="COG0344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2974931_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="58" mass="6744" checksum="81A7B0ABD478538A" modified="2004-07-05" version="1">MYCGNFGTLGPIKNQIPKTELFYFSINFATLIIIAKHYSNILRLINGTENKFNFKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQD9</accession>
    <name>Q6YQD9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal kinase</fullName>
            <ecNumber evidence="1">2.7.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pdxK</name>
        <name evidence="3" type="ordered locus">PAM_434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.35" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_434"/>
    <dbReference type="EnsemblBacteria" id="BAD04519">
        <property type="protein sequence ID" value="BAD04519"/>
        <property type="gene ID" value="PAM_434"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_434"/>
    <dbReference type="eggNOG" id="COG2240">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046496_3_1_14"/>
    <dbReference type="OMA" id="CPNQLEL"/>
    <dbReference type="OrthoDB" id="1480223at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-515-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008478">
        <property type="term" value="F:pyridoxal kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009443">
        <property type="term" value="P:pyridoxal 5'-phosphate salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01173">
        <property type="entry name" value="pyridoxal_pyridoxamine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004625">
        <property type="entry name" value="PyrdxlKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534">
        <property type="entry name" value="PTHR10534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00687">
        <property type="entry name" value="pyridox_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="2">
        <location>
            <begin position="79"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="288" mass="32697" checksum="E2571B517E9978A2" modified="2004-07-05" version="1">MNIPTKPKSILSIQSHVVYGYVGNKEAVYPLQNMNFDVWPINTVQFSNHTGYQKWQGQIFNKQNIVDLVEGLFALGVEKQCQAILTGYMGSLDICEAVLEIVARFKRTNPDILYLCDPVMGNNRCFVKPEITSFFKNNLQADIITPNQFEAEFLSGIKINNVSDAIKVAKHFHNLGVKIVIITGINFQDEKYFQVFASNATKKYLVQAHNKEKNIDIAGTGDLFASLFLGFYLKYERNIKNALAHAVFYLNKVVQNTLLSQQKELQCLSVLYKQVNLAKLPQVMEIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQF6</accession>
    <name>Q6YQF6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_351</name>
        <name evidence="3" type="ordered locus">PAM_417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_351"/>
    <dbReference type="EnsemblBacteria" id="BAD04436">
        <property type="protein sequence ID" value="BAD04436"/>
        <property type="gene ID" value="PAM_351"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04502">
        <property type="protein sequence ID" value="BAD04502"/>
        <property type="gene ID" value="PAM_417"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_351"/>
    <dbReference type="KEGG" id="poy:PAM_417"/>
    <dbReference type="HOGENOM" id="CLU_2168401_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-419-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-503-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="105" mass="12249" checksum="6D3433EF60A9C549" modified="2004-07-05" version="1">MDKKQKIKKEFYEHCQCCGSDLGMNINDIDLNLFGVIMGLMIFFSLGFFVLFGFLSLFSSFQINNEILATLIYIFFTGILSFCLIAHFMPKLLFEKLDYEKVEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQF9</accession>
    <name>Q6YQF9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04499">
        <property type="protein sequence ID" value="BAD04499"/>
        <property type="gene ID" value="PAM_414"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_414"/>
    <dbReference type="HOGENOM" id="CLU_065991_0_0_14"/>
    <dbReference type="OMA" id="YQITEYN"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-499-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="134"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="262"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="326" mass="38836" checksum="69E3E09CE06AED3B" modified="2004-07-05" version="1">MSSFRIGNKHYKIIPFLITTGTLLFFVFWIGGISYKYHLETEERRKLQEVDIKVKARELNNDIYNENKKLKKENEYMKDTPYEFQRYNGEKEYYNLFNHKLVKKIDKDDTIWEYDKNNGLLLKKTDRYNNVEEYGLHGKLIKKTLSDGVWMEYNPVNQKLMKRKNIDNSIEEFDDNEEKFKEIDKNGKVKFFKTKLYQNISDFKKLFINDKGLEKAFLESRIFNLKDLKASGYTWEQLISVGYSSQDLKASGYTLTTQKIHYQKDGKTIFYIETFDYQTGKKIKKVTYEEDGETLDCIETFDSQTGEKIDKIIYKPDGTVSLKITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQG8</accession>
    <name>Q6YQG8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_383</name>
        <name evidence="3" type="ordered locus">PAM_405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04468">
        <property type="protein sequence ID" value="BAD04468"/>
        <property type="gene ID" value="PAM_383"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04490">
        <property type="protein sequence ID" value="BAD04490"/>
        <property type="gene ID" value="PAM_405"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_383"/>
    <dbReference type="KEGG" id="poy:PAM_405"/>
    <dbReference type="HOGENOM" id="CLU_1720488_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-459-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-484-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="152" mass="17851" checksum="9856F32448DE3E02" modified="2004-07-05" version="1">MEIKSFILIISLILNVILILFSIIKTIQCNKKLKFEDLTKKEFELKCVELICSGEISFENNKKVLKAMQKLHKEIFLDTIPKKKNNHKPRPFQGLFLFNNTHNFGKETKTMFIKKSFNLYLVISSFSSSLYFHLFQLSPFIMFLNSIFSLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQG9</accession>
    <name>Q6YQG9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_382</name>
        <name evidence="4" type="ordered locus">PAM_404</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">Onion yellows</strain>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04467">
        <property type="protein sequence ID" value="BAD04467"/>
        <property type="gene ID" value="PAM_382"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04489">
        <property type="protein sequence ID" value="BAD04489"/>
        <property type="gene ID" value="PAM_404"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_382"/>
    <dbReference type="KEGG" id="poy:PAM_404"/>
    <dbReference type="HOGENOM" id="CLU_2290092_0_0_14"/>
    <dbReference type="OMA" id="TNINKCQ"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="SVM_signal" evidence="2">
        <location>
            <begin position="6"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="107" mass="12954" checksum="1BAAAFDBAE5614D0" modified="2004-07-05" version="1">MRFHMIFKSQKYLLIFNIILFICLGLLLINNNNQVMAMDKLNNELIKETNINKCQEQIQQLEQISKYSKEDEKINNDNLEKQKNHFFKLFIKQIVIKLMFIEININF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQJ4</accession>
    <name>Q6YQJ4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04464">
        <property type="protein sequence ID" value="BAD04464"/>
        <property type="gene ID" value="PAM_379"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_379"/>
    <dbReference type="HOGENOM" id="CLU_959212_0_0_14"/>
    <dbReference type="OrthoDB" id="2121724at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-454-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="285" mass="32342" checksum="C5261ADF4A7B4259" modified="2004-07-05" version="1">MAKQTNKNTKNQSKNNKSNKIIIKRKNPTPKIIIETQTKKENWWLKITKAFFKILIWCIPLLLIGGAIYWTLFKFFPEVLNQITAFTGNAVAKTKLLYDKATQPIRKVIEYIYNKVTGNDKDPNHTLSLKEKIGYYLTTTLSVVGICFGLVKISNWLKSGKKKTIKKSTKAIIQKKATSKIANVSGKILKIGSKALFWISLASTAYELYQFYQEETKIPNPPQQLTNKMENPPTPIFQNPSIQQQPNNELPTIDNLTQENTAGPLSSIIDNPTQEERITGNLNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQJ7</accession>
    <name>Q6YQJ7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_376"/>
    <dbReference type="EnsemblBacteria" id="BAD04461">
        <property type="protein sequence ID" value="BAD04461"/>
        <property type="gene ID" value="PAM_376"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_376"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1935901_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-450-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="130" mass="15381" checksum="8922ABD73AC5DF4E" modified="2004-07-05" version="1">MNYQEKIKHIQTHFPMSVLLKKLNIIPPNFNINHRFPCPIHQGKNPTCCHFTSDNKIHCWKCCKDYDIIDVYMAIRQIKSFHEAIQKIAGFMNSFEFKALNKQEKEITKITINPLKQLYQPMKSKQSVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQL2</accession>
    <name>Q6YQL2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_321</name>
        <name evidence="2" type="ordered locus">PAM_361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">Onion yellows</strain>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_321"/>
    <dbReference type="EnsemblBacteria" id="BAD04406">
        <property type="protein sequence ID" value="BAD04406"/>
        <property type="gene ID" value="PAM_321"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04446">
        <property type="protein sequence ID" value="BAD04446"/>
        <property type="gene ID" value="PAM_361"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_321"/>
    <dbReference type="KEGG" id="poy:PAM_361"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1617329_0_0_14"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-382-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-430-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="164" mass="19049" checksum="8DB68EE1FF65E7EB" modified="2004-07-05" version="1">MYHKYKQHPLLKMSPVDKRQTLCFNNGKRGAKKATPKLLEDLDFKKAVLFALNRSDVGETVDVFSDGELAVVPKITSFLEEPLMYNESEEHKANIQDFEPENKGYNPTKAYELFKKAYNHLFDADKQKTVEIEFLVAKTQEERVNLARFVKNQLENCFNQQGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQM3</accession>
    <name>Q6YQM3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_350"/>
    <dbReference type="EnsemblBacteria" id="BAD04435">
        <property type="protein sequence ID" value="BAD04435"/>
        <property type="gene ID" value="PAM_350"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_350"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073330_0_0_14"/>
    <dbReference type="OrthoDB" id="1779749at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-418-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="281" mass="33826" checksum="BEB006EF83010BE3" modified="2004-07-05" version="1">MLPSDLEEVLQLKLKMKPDYSQVKKRREACENQYAQWRQGFNQYLDKPKDETRIECRYTFDGLNGINYYNRRYSQIQSELNNINQQLTKIHQENKISQLEQELVTLNQTPDKYEQTIKDKNQEIIDIKNRLKNLPAQEENLRKELKLVENRRELQKEPSNLVCYIKDRHPFDRWNNKGLTYKETSINGFKFSRFDKEDDSQLYLYVKLEKQFKENSSGNCLILKYQGPKHFLDDDKDYYLGRARVSDSNFELTNFHLHFNPVRKTLSIFKDKHNVINPNIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQN4</accession>
    <name>Q6YQN4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04424">
        <property type="protein sequence ID" value="BAD04424"/>
        <property type="gene ID" value="PAM_339"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_339"/>
    <dbReference type="HOGENOM" id="CLU_1609154_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="142" mass="17041" checksum="05AC970B3FB456AB" modified="2004-07-05" version="1">MIYYKIPIKQQQTYYFFLYDLFKNKINNMNHAHSIIRPKIDKYFNKMTKINLKEKIKMKNDLNKGIRIGGWNTKTTPTDLDQIKLFLQTLKQDLINLTIITHSKKKNTYQEANYRPKNQTLFVDPQILDEIKQTKITLINDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQR0</accession>
    <name>Q6YQR0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_313"/>
    <dbReference type="EnsemblBacteria" id="BAD04398">
        <property type="protein sequence ID" value="BAD04398"/>
        <property type="gene ID" value="PAM_313"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_313"/>
    <dbReference type="HOGENOM" id="CLU_1232954_0_0_14"/>
    <dbReference type="OrthoDB" id="2116149at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-373-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="224" mass="26591" checksum="2DD02B9FADD43A36" modified="2004-07-05" version="1">MWNLLMILKMIFSFNFLKYLISFDFKDFFYLLYSIFYSIFFTKSSFLFGFNVGWNINFINIYNVIKTIFIFMWEQLTTLIYPLKLFSSLFDFLMQILKIFIDVFGSIIGYIKSSITSLTGQKLMDPSESMWEKIKEIAKLIFSVAVGGSVIYFLKEINNFLLNSFIKIGDLLFKIVLRILDIISIVLKSFLFLFKKVIIILSFVLSFFINFLYLWVFENAKKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQR4</accession>
    <name>Q6YQR4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipoate--protein ligase</fullName>
            <ecNumber evidence="4">6.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lplA</name>
        <name evidence="9" type="ordered locus">PAM_309</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-lipoate + ATP + L-lysyl-[lipoyl-carrier protein] = (R)-N(6)-lipoyl-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10500"/>
            <dbReference type="Rhea" id="RHEA-COMP:10502"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.20" evidence="4"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_309"/>
    <dbReference type="EnsemblBacteria" id="BAD04394">
        <property type="protein sequence ID" value="BAD04394"/>
        <property type="gene ID" value="PAM_309"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_309"/>
    <dbReference type="eggNOG" id="COG0095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022986_0_2_14"/>
    <dbReference type="OMA" id="RTCPEDD"/>
    <dbReference type="OrthoDB" id="871298at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-368-MON"/>
    <dbReference type="UniPathway" id="UPA00537">
        <property type="reaction ID" value="UER00594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016979">
        <property type="term" value="F:lipoate-protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019491">
        <property type="entry name" value="Lipoate_protein_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004562">
        <property type="entry name" value="LipoylTrfase_LipoateP_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561">
        <property type="entry name" value="PTHR12561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10437">
        <property type="entry name" value="Lip_prot_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00545">
        <property type="entry name" value="lipoyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="8">
        <location>
            <begin position="30"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="338" mass="39140" checksum="862D14DD155A634E" modified="2004-07-05" version="1">MILIQINRICDLKPYFYYALEQYALNHLLKQNPEKSFFFIWKIKGVVVGKNQIIENEVNLDYLKEHKIPLFRRPTGGGCVYNDPQTPLFSIIAKKEKNFSFKPFLAKIVVALQKLGLNVEFSGRNDILLEGKKISGNAFIQNQNGMVTHGTLLYNCDFQTMINTITPNDQKLISKGIASVRSRVTNLKGYLPDMSQEKLMQYLTEALTDQTYVLSDQEIKSIEKDSLQFASNEFLFLTQPHHTKILKKRFSWGGLEIFLDIRFGLIEKMTLIGDFFHKEDNLEQFSKLFEGITYQTEKIQEVLEKTNIGFYILDATNDDFLSLLKEGILEEKLKNLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQS2</accession>
    <name>Q6YQS2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_301"/>
    <dbReference type="EnsemblBacteria" id="BAD04386">
        <property type="protein sequence ID" value="BAD04386"/>
        <property type="gene ID" value="PAM_301"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_301"/>
    <dbReference type="eggNOG" id="COG2179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056221_4_0_14"/>
    <dbReference type="OMA" id="VLNPYHI"/>
    <dbReference type="OrthoDB" id="1472357at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-359-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027706">
        <property type="entry name" value="PGP_Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010021">
        <property type="entry name" value="PGPP1/Gep4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF25">
        <property type="entry name" value="PTHR19288:SF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09419">
        <property type="entry name" value="PGP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01668">
        <property type="entry name" value="YqeG_hyp_ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="189" mass="22290" checksum="5EBAA5C1A3D91729" modified="2004-07-05" version="1">MSNKMTCPNKLFIPQHYFPCVLQIPFELFQKQGIKALIFDLDNTLIECNKDILDEQIKNLLTKLSLIFKVVILSNASKKRLHKVLKNDFTFIYLNLLNKKPSPTAFQKACQLLKLETTQMLMIGDQLQTDIKGANQAGFCSLLVKPLNRFQESAFTKFNRFYREKKFLTNLKKQDYHLWKKKFQDFEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQS8</accession>
    <name>Q6YQS8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">plsC</name>
        <name evidence="3" type="ordered locus">PAM_295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_295"/>
    <dbReference type="EnsemblBacteria" id="BAD04380">
        <property type="protein sequence ID" value="BAD04380"/>
        <property type="gene ID" value="PAM_295"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_295"/>
    <dbReference type="eggNOG" id="COG0204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027938_6_1_14"/>
    <dbReference type="OMA" id="CARIRQG"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-353-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="101"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="269" mass="30747" checksum="EE69041C30E7F933" modified="2004-07-05" version="1">MLTFIFVVVWLTFVFLQTSKTMLVDFSFCYKLPVNLILGLLLAFLITFIILVFCLVLMTFPPPNHYFKGFVSRSLSRFVNRFLRIKVVVQNPHLIPSKENVVIYANHKSYTDPFVITSVIPRTLSFAPKQNFNCFFGTAWFLKLAFLSLDCMVISRDDIRKTAQNLIKAVPKVKNGMAMVVFPEGGIKDRNNEQAMPLLGGAFKIACKSKSSILPLTIKGASQIKNKRFWQKKVVEIIIHPPLKYDHYCNTNMHQVAIDVQNIINSSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQT1</accession>
    <name>Q6YQT1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acetylornithine deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argE</name>
        <name evidence="1" type="ordered locus">PAM_292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_292"/>
    <dbReference type="EnsemblBacteria" id="BAD04377">
        <property type="protein sequence ID" value="BAD04377"/>
        <property type="gene ID" value="PAM_292"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_292"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1872258_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-350-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="147" mass="16836" checksum="3ED75919E2E1985C" modified="2004-07-05" version="1">MDEKTTNLTCQSGFLILEKQQAFFTLNLRYPKGITFEKILFQLEKAAKKNQFLLKTDFHYPIMYINPNSELITTLVNIYQKHTHDFLTAPLCSGGRTYAKCAPNLVPFGPVFPNQKSLAHQVDESISIDQLITLTAIYTEVLYLLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQT3</accession>
    <name>Q6YQT3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetylornithine deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">argE</name>
        <name evidence="4" type="ordered locus">PAM_290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_290"/>
    <dbReference type="EnsemblBacteria" id="BAD04375">
        <property type="protein sequence ID" value="BAD04375"/>
        <property type="gene ID" value="PAM_290"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_290"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031786_2_0_14"/>
    <dbReference type="OMA" id="GYAGHIE"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-348-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010964">
        <property type="entry name" value="M20A_pepV-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01887">
        <property type="entry name" value="dipeptidaselike"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="254"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="458" mass="50980" checksum="1B13338E2C1962A7" modified="2004-07-05" version="1">MIDFKKEVLKRKDALIEALQTLLKINTELTTFDPNRTGAPFGEGNQQALDFMLDLGSQSGFKTLNLEGYAGHIEYGNQKEWVGMIGHLDVVPAGTGWDYPPYAALIVDGTLYGRGTQDDKGPTMAAFWALKILHELNLPLSKRIKLILGVDEETGFRCMKHYFKQIPELPVSGFVPDSHFPAIYCEKGIGGFTFEGTVLDNRIVSIQSGQASNVVPDLAQAVLKFDPNYSDLFHNFVKNNSIKATLEPQGDLLKLEVHGVSAHGSTPETGKNALYDLMKVLKALGITNTLVDFFDQYLVDSLDGKKLGINHFDEETYNLVCFSGVLKLENNQAFFTLNLRYPKGITFEKILFQLEKAAKSQHFCLKTTLHHPIMYVDPKSELMQTLLKVYQKHTNDLVSKPMCVGGGSFAKCAPNLVPFGPTFVDEVSLIHQKNESISIDKLITLTAIYTEALYELAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQU3</accession>
    <name>Q6YQU3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Na+-driven multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">norM</name>
        <name evidence="2" type="ordered locus">PAM_280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_280"/>
    <dbReference type="EnsemblBacteria" id="BAD04365">
        <property type="protein sequence ID" value="BAD04365"/>
        <property type="gene ID" value="PAM_280"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_280"/>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_512714_0_0_14"/>
    <dbReference type="OMA" id="LNCIMMG"/>
    <dbReference type="OrthoDB" id="257836at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-338-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="426"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="496"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="531" mass="59091" checksum="AFD20DBE4B6A5CF5" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQV0</accession>
    <name>Q6YQV0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized BCR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_273"/>
    <dbReference type="EnsemblBacteria" id="BAD04358">
        <property type="protein sequence ID" value="BAD04358"/>
        <property type="gene ID" value="PAM_273"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_273"/>
    <dbReference type="eggNOG" id="COG1692">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068238_1_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005235">
        <property type="entry name" value="YmdB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36303">
        <property type="entry name" value="PTHR36303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13277">
        <property type="entry name" value="YmdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="153" mass="17540" checksum="1D7D6D1F13E78A15" modified="2004-07-05" version="1">MKIMFIGDIYGNPGISYFAEKVGFLKETYKPNLIIANAENADNGKGLSFKIYKKLQKLGVDLMTMGNHVWKNKQIKNFIDKSNVIRPINDTQQLGQGYKIIDCEDKKILVMNALGRVFINSKLRCPFKTIDNVLEQNKAKYDFSFFGFSCRSH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQY4</accession>
    <name>KCY_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytidylate kinase</fullName>
            <shortName evidence="1">CK</shortName>
            <ecNumber evidence="1">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cytidine monophosphate kinase</fullName>
            <shortName evidence="1">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cmk</name>
        <name type="ordered locus">PAM_239</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQY4"/>
    <dbReference type="SMR" id="Q6YQY4"/>
    <dbReference type="STRING" id="262768.PAM_239"/>
    <dbReference type="EnsemblBacteria" id="BAD04324">
        <property type="protein sequence ID" value="BAD04324"/>
        <property type="gene ID" value="PAM_239"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_239"/>
    <dbReference type="eggNOG" id="COG0283">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079959_0_2_14"/>
    <dbReference type="OMA" id="RAITWWM"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000131949" description="Cytidylate kinase">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="12"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <sequence length="223" mass="25106" checksum="47A213F09BDC2EBD" modified="2004-07-05" version="1">MHMKSFKIAIDGPAGSGKSTISKKLSQKLGWNHVDTGAMFRALTLYLLENEVSWHHEKSLNQALDKINLSYSCNKIFLNQEDVSLKIKSLDVEKHVSSVALIPAVRTKLLKLQKEICGNTPNLIMDGRDIGTVVMPDANLKIFLTANITKRALRKQQEDAQKGKITDIAQIMKQLKERDHKDYHRQLAPLSKALDAILLDTTELSIDEVIAKIIALIDKKRRT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-10-11" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQY6</accession>
    <name>TRUB_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="1">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="1">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">truB</name>
        <name type="ordered locus">PAM_237</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQY6"/>
    <dbReference type="SMR" id="Q6YQY6"/>
    <dbReference type="STRING" id="262768.PAM_237"/>
    <dbReference type="EnsemblBacteria" id="BAD04322">
        <property type="protein sequence ID" value="BAD04322"/>
        <property type="gene ID" value="PAM_237"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_237"/>
    <dbReference type="eggNOG" id="COG0130">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032087_0_1_14"/>
    <dbReference type="OMA" id="ELQFIRW"/>
    <dbReference type="OrthoDB" id="1166299at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-285-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000121879" description="tRNA pseudouridine synthase B">
        <location>
            <begin position="1"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <sequence length="283" mass="32761" checksum="125DA68DE481220E" modified="2004-07-05" version="1">MNGFFLVNKPEKMTSHDVVFQIKKKFHFDKVGHTGTLDPLASGLLIICVGKATKLAFLFDKLPKTYQGTFLFNKHYDTLDVTGKLLDTKNTPLTDCNIQKSFASFHQKKYLQIPPMFSAVKIKGKKMYRLARKNQVVDIPPREVFIHHFEKTSLFCRDQVDFLAHVSKGTYIRSLARDLALQLNTYGALLRLQRTAIGTHLLQNAKTIENLELNDLILDSTFFAAYDELILNDYLIKLVKNGTHLDQRQITTKKPFIVKDSNKNFVAYYDTLDENKYYPRYFF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-07-24" modified="2022-08-03" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQZ5</accession>
    <name>RPOA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase subunit alpha</fullName>
            <shortName evidence="1">RNAP subunit alpha</shortName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">RNA polymerase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Transcriptase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpoA</name>
        <name type="ordered locus">PAM_227</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase alpha chain family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="frameshift">
            <sequence resource="EMBL-CDS" id="BAD04312" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04312.1"/>
        <property type="status" value="ALT_FRAME"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQZ5"/>
    <dbReference type="SMR" id="Q6YQZ5"/>
    <dbReference type="STRING" id="262768.PAM_227"/>
    <dbReference type="PRIDE" id="Q6YQZ5"/>
    <dbReference type="EnsemblBacteria" id="BAD04312">
        <property type="protein sequence ID" value="BAD04312"/>
        <property type="gene ID" value="PAM_227"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_227"/>
    <dbReference type="eggNOG" id="COG0202">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053084_0_1_14"/>
    <dbReference type="OMA" id="LMKFRNF"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00059">
        <property type="entry name" value="RNApol_bact_RpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02027">
        <property type="entry name" value="rpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000296845" description="DNA-directed RNA polymerase subunit alpha">
        <location>
            <begin position="1"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha N-terminal domain (alpha-NTD)" evidence="1">
        <location>
            <begin position="1"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha C-terminal domain (alpha-CTD)" evidence="1">
        <location>
            <begin position="245"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="330" mass="36761" checksum="BB7B245EE43BDF2B" modified="2007-07-24" version="2">MKNIKFIKPFFVEEIDENPISGKFIIKPLERGYGITVGNALRRVLLSSLPGTAIVNVKIQGVEQEFTTIPGVYEDVMTIILNLKKIVFAVDDESDDFEEKLELIAKGPQRLTASSFELPAGVKIINPDHYITTLSDDVCFHMTVTLKKGIGYVGAKDNKVHGENQVGVIAIDSLFTPVVNVSYQVEKKLGNKDELTIEITTNGALLAKEALATAASILVDHFNVLVELSQKPAHVEFVSESKKEAHNSVLDLEIEQLDLSVRLFNSLKRAGIDTVAALVKLSEKEVVKLKSLGRKSFQELKDKFLEYGLEFNDYLKEVLHHSVEEDKDKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="111" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR03</accession>
    <name>Q6YR03_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">rplO</name>
        <name evidence="10" type="ordered locus">PAM_219</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_219"/>
    <dbReference type="EnsemblBacteria" id="BAD04304">
        <property type="protein sequence ID" value="BAD04304"/>
        <property type="gene ID" value="PAM_219"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_219"/>
    <dbReference type="eggNOG" id="COG0200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055188_4_2_14"/>
    <dbReference type="OMA" id="FKNINRV"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="9">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="126" mass="13671" checksum="A47D1594057CA163" modified="2004-07-05" version="1">MEPGSGTGKTSGKGHKGQLARSGKTLRPGFEGGQIPFFQRIPKRGFHNFAQKRYALLNLKTLENFPQDTVVTPQLLLEKKIIKDQLCGIKVLAQGTLTKKLVVKASKFSKQAQAAILAVGGNIEVI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-08-30" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR05</accession>
    <name>RS5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsE</name>
        <name type="ordered locus">PAM_217</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text>The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR05"/>
    <dbReference type="SMR" id="Q6YR05"/>
    <dbReference type="STRING" id="262768.PAM_217"/>
    <dbReference type="EnsemblBacteria" id="BAD04302">
        <property type="protein sequence ID" value="BAD04302"/>
        <property type="gene ID" value="PAM_217"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_217"/>
    <dbReference type="eggNOG" id="COG0098">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065898_2_2_14"/>
    <dbReference type="OMA" id="KRGCGSW"/>
    <dbReference type="OrthoDB" id="1505038at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-263-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000131564" description="30S ribosomal protein S5">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="S5 DRBM" evidence="1">
        <location>
            <begin position="15"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <sequence length="171" mass="18524" checksum="64B4237A0F9D5077" modified="2004-07-05" version="1">MKAIKKEFNKKAPLLEEKVVKINRITKVVKGGARFRFSALVVVGDKKGQIGFATAKAKEIVEAIKKALEKAKKQLVRIPITGTTIPHDTIGRFGASKFFLKPASKGTGIVAGGKAARTILELVGINDVLTKTFGSRTSINVIRAVMDGLQSLRTKEEVAKLRGITLAKKEQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-01-10" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR14</accession>
    <name>RL16_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplP</name>
        <name type="ordered locus">PAM_207</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR14"/>
    <dbReference type="SMR" id="Q6YR14"/>
    <dbReference type="STRING" id="262768.PAM_207"/>
    <dbReference type="EnsemblBacteria" id="BAD04292">
        <property type="protein sequence ID" value="BAD04292"/>
        <property type="gene ID" value="PAM_207"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_207"/>
    <dbReference type="eggNOG" id="COG0197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078858_2_1_14"/>
    <dbReference type="OMA" id="KGAVEYW"/>
    <dbReference type="OrthoDB" id="1786618at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-253-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_0000062159" description="50S ribosomal protein L16">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <sequence length="140" mass="15712" checksum="48FE9C0EE4649045" modified="2004-07-05" version="1">MLMPKRTKYRRPHRVSFEGKSKGKNVIANGNHALVAKEGAFITNKQIEAARIAMTRYMKRTGKVWINIFPHLSLTKKPLEVRMGSGKGSPEEWVAVVKTGKVLFEVKDTTNSSKVEMEALRLASHKLPIKTKIVKKGAEV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-09-22" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR18</accession>
    <name>RL23_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplW</name>
        <name type="synonym">pam202</name>
        <name type="ordered locus">PAM_202</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR18"/>
    <dbReference type="SMR" id="Q6YR18"/>
    <dbReference type="STRING" id="262768.PAM_202"/>
    <dbReference type="EnsemblBacteria" id="BAD04287">
        <property type="protein sequence ID" value="BAD04287"/>
        <property type="gene ID" value="PAM_202"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_202"/>
    <dbReference type="eggNOG" id="COG0089">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037562_3_2_14"/>
    <dbReference type="OMA" id="FEVDHRA"/>
    <dbReference type="OrthoDB" id="1978865at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-248-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000215040" description="50S ribosomal protein L23">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <sequence length="96" mass="11010" checksum="462E9974D364FC31" modified="2004-07-05" version="1">MNKYYDLVKAPIITELTNKLIERQNKYTFKVAKTANKVEIKKALESIFQVKVLSVNTRNVLPQFKRKGKFEGYTSGYKKAICKVAPGQKIEILANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR21</accession>
    <name>Q6YR21_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04282">
        <property type="protein sequence ID" value="BAD04282"/>
        <property type="gene ID" value="PAM_197"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_197"/>
    <dbReference type="HOGENOM" id="CLU_2303039_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-241-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="100" mass="10939" checksum="E266A9C0F76415D3" modified="2004-07-05" version="1">MLFSTKPSRVNNSTSNLISAETNLLSLVRANLESLVYTSKSLLSCVLTFAPTLNLSVLSTSLTLNVGKNTFKKHFLVVSLFSKPFTEAKHKNGASTKLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR33</accession>
    <name>Q6YR33_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized BCR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">PAM_185</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_185"/>
    <dbReference type="EnsemblBacteria" id="BAD04270">
        <property type="protein sequence ID" value="BAD04270"/>
        <property type="gene ID" value="PAM_185"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_185"/>
    <dbReference type="eggNOG" id="COG1284">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1022467_0_0_14"/>
    <dbReference type="OMA" id="YFTITTA"/>
    <dbReference type="OrthoDB" id="1064978at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-226-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003740">
        <property type="entry name" value="YitT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02588">
        <property type="entry name" value="YitT_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="272" mass="30887" checksum="B3DD2157BE8E382F" modified="2004-07-05" version="1">MKNGMKNIEKFPPIKKKIQYVQEFKKILILSLSLIVYVLVSVWAFDCTRDGGYKTDLFPTGVIGLGDVIGKLLHKAGKIETNNIIVIAGTFYFVVNVFLLFFISRRYLGKYFTITTAFATVLLFVSVFFIENQVKQGFLYHTERFFGIFKTESDFLSDLTRVFFAGILIGIFNGIPVRIGASTGGLDIVAKYLFVYKKKDISFVVEMFGYTLMIFGAVGVFIIEYFYKETGLKELTTQISLSLFYTVLRIKLSALFMGLITSVPQKETKLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR40</accession>
    <name>Q6YR40_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oligoendopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">PAM_178</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_178"/>
    <dbReference type="MEROPS" id="M03.010"/>
    <dbReference type="EnsemblBacteria" id="BAD04263">
        <property type="protein sequence ID" value="BAD04263"/>
        <property type="gene ID" value="PAM_178"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_178"/>
    <dbReference type="eggNOG" id="COG1164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030403_1_0_14"/>
    <dbReference type="OMA" id="CAFQFWK"/>
    <dbReference type="OrthoDB" id="1935578at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-218-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011976">
        <property type="entry name" value="Pept_M3B_oligopep-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02289">
        <property type="entry name" value="M3_not_pepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="165"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="562" mass="65948" checksum="C58ED4BA2F11F417" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR42</accession>
    <name>Q6YR42_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04261">
        <property type="protein sequence ID" value="BAD04261"/>
        <property type="gene ID" value="PAM_176"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_176"/>
    <dbReference type="HOGENOM" id="CLU_1222724_0_0_14"/>
    <dbReference type="OMA" id="QKHIIAS"/>
    <dbReference type="OrthoDB" id="1382377at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-215-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="226" mass="26476" checksum="FF015FE877BDE29B" modified="2004-07-05" version="1">MLKTKNKETKVFFSPLQKHIIASTFLGFTIVLEFAYDKLGIAKMGANIGSFIKVSLLPLILIGFLLGKKHSFLFCTLYALFHLFKAIFLSESTNILVYMQAQQMRPLQQIAVLLLDYLLVDLSYSLSFVFYTPNLKYFDNYKSILLNLLIVFTSVFAFKCLASYFIWLPLIANKQNYFPFLAPLINYPIIWCFCYNLIPVFATFIFIFIFLFFLNPRIKTYLNYYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR47</accession>
    <name>Q6YR47_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cof</name>
        <name evidence="1" type="ordered locus">PAM_171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_171"/>
    <dbReference type="EnsemblBacteria" id="BAD04256">
        <property type="protein sequence ID" value="BAD04256"/>
        <property type="gene ID" value="PAM_171"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_171"/>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044146_7_0_14"/>
    <dbReference type="OMA" id="QVWLFEP"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-210-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="265" mass="30368" checksum="2EDD1FEB47273434" modified="2004-07-05" version="1">MKQKKESLFIFDIDGTLLSSKYKKIFPQTIKAIQTLAQNPDNVLAVATGRNIKRIDVLGNLLPYFKHFVFFNGGLTKYFDKVIDDRPFKKEVVKELIAKAHQAKIHIGLTGMTQEIVPSPQDLIPPSLGELYCTNKKSVVDPEFHLHNNVYQVWLFEPNKEKLQNFLKDLKDLQAYYWRTNGGVDLVPQSVNKTCGIKKLKELYPHHQLVCVGDGYNDVEMLKLADVGIGLENTNCQEIKDNCNLLAPHIDDDKFYDFLKLHHLV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-01" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR57</accession>
    <name>ACKA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetate kinase</fullName>
            <ecNumber evidence="1">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ackA</name>
        <name type="ordered locus">PAM_159</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR57"/>
    <dbReference type="SMR" id="Q6YR57"/>
    <dbReference type="STRING" id="262768.PAM_159"/>
    <dbReference type="EnsemblBacteria" id="BAD04244">
        <property type="protein sequence ID" value="BAD04244"/>
        <property type="gene ID" value="PAM_159"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_159"/>
    <dbReference type="eggNOG" id="COG0282">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020352_0_1_14"/>
    <dbReference type="OMA" id="KIITCHI"/>
    <dbReference type="OrthoDB" id="537106at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-193-MON"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000107596" description="Acetate kinase">
        <location>
            <begin position="1"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="203"/>
            <end position="207"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="278"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="326"/>
            <end position="330"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <sequence length="410" mass="45310" checksum="1B277959F9F3420D" modified="2004-07-05" version="1">MKIMSVNSGSSSLKFQLLEMPQQEVIVSGLVERIGSNQAVFTMKTKDKKDKQVLEVLNHQTAVELLLDALIQKKVINTLEEIEGVGHRVVQGGEIFSDSAVLTEKTLAQIESLCDLAPLHNPANIISIKAFQKVLPQVFQVAVFDTTFHQSMPAVNFLYAAPYYWYQKYQIRKYGAHGTSYKYITEQMQQILGKKNAKIIICHAGNGVSLCAVDSGKSVDTSMGFTPLEGVPMGTRSGNIDPAVVKFIAEKENKTVACVIDDLNKKSGYLGVSGISNDTRDILANIKEGNQQAILSHDIQVKRIVDYIASYYVLLKGVDALVFTAGIGENSSFFRSEIIKRLSVLGIKLDEEKNKVQGKQELITTFDSAIKAFVVPTNEELAIAQDVLRLQQNQTNQDKDDQQECFCCCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR60</accession>
    <name>Q6YR60_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04241">
        <property type="protein sequence ID" value="BAD04241"/>
        <property type="gene ID" value="PAM_156"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_156"/>
    <dbReference type="HOGENOM" id="CLU_2233759_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="105" mass="12575" checksum="868EA51793A2B5D3" modified="2004-07-05" version="1">MMALTDLDIIKRIITYAKYFNPRAQKTNYYKFRIYFRADNLEQGFQRVLQDANKNQLLPTKTNPAFNLSLLIKVSFALVAFTIVMFVLIYYFKKYLKNKRLRGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR61</accession>
    <name>Q6YR61_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">PAM_155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_155"/>
    <dbReference type="EnsemblBacteria" id="BAD04240">
        <property type="protein sequence ID" value="BAD04240"/>
        <property type="gene ID" value="PAM_155"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_155"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_9_4_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AAA_lid_3" evidence="3">
        <location>
            <begin position="38"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M41" evidence="2">
        <location>
            <begin position="96"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="239" mass="26854" checksum="1B4739BDB8449CA1" modified="2004-07-05" version="1">MLRPGRFDRTMQVYLPDVKAREAILKIHSRNKKIDPLVDFSHLAKRTPGMNGAQLAAVLNEASLLAAKNQKAFITMDELEESVDKVYMGPAKKSLVIHEIERKMTAYHEAGHAVIVMKHPHSSEKVRTLTITPRGGALGYMWPTSDKEYFCNTEKQLTYNIVVALGGAAAEELFSKARTNGVYSDLKQATRTAFGMVAYSGISPLGYINFEKCSEQTRYQVDQEIKKIVDECYKQAKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR69</accession>
    <name>Q6YR69_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2779 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_147"/>
    <dbReference type="EnsemblBacteria" id="BAD04232">
        <property type="protein sequence ID" value="BAD04232"/>
        <property type="gene ID" value="PAM_147"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_147"/>
    <dbReference type="eggNOG" id="COG2251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_441239_0_0_14"/>
    <dbReference type="OMA" id="YCKQDTW"/>
    <dbReference type="OrthoDB" id="432299at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-179-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021301">
        <property type="entry name" value="DUF2779"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11074">
        <property type="entry name" value="DUF2779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2779" evidence="1">
        <location>
            <begin position="389"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="618" mass="73115" checksum="E02D1645E008A400" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR71</accession>
    <name>Q6YR71_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="5">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">ppa</name>
        <name evidence="6" type="ordered locus">PAM_145</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_145"/>
    <dbReference type="EnsemblBacteria" id="BAD04230">
        <property type="protein sequence ID" value="BAD04230"/>
        <property type="gene ID" value="PAM_145"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_145"/>
    <dbReference type="eggNOG" id="COG0221">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073198_1_2_14"/>
    <dbReference type="OMA" id="DEPTFPG"/>
    <dbReference type="OrthoDB" id="1767807at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-177-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00209">
        <property type="entry name" value="Inorganic_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="184" mass="21324" checksum="008D29595D6B0E0C" modified="2004-07-05" version="1">MNILHDINPERITKEEFIVVIEISQGSKKKYEIDKETGLLLLDRFLTTAFRYPINYGFVPLTHCEDNDPLDVLVLSQEILDPMTLVKCRPLGVIKMIDNDELDEKVIAVPVFDKYFSHLQDLKDMPLPMIAEIKHFFENYKALEKKKVVIEAIQDKQAAFSAIETSLLTYQKVIKPSLKKEKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="119" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR73</accession>
    <name>Q6YR73_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable tRNA sulfurtransferase</fullName>
            <ecNumber evidence="6">2.8.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Sulfur carrier protein ThiS sulfurtransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Thiamine biosynthesis protein ThiI</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA 4-thiouridine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">thiI</name>
        <name evidence="9" type="ordered locus">PAM_143</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[ThiI sulfur-carrier protein]-S-sulfanyl-L-cysteine + a uridine in tRNA + ATP + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = [ThiI sulfur-carrier protein]-L-cysteine + a 4-thiouridine in tRNA + AMP + diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24176"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:13337"/>
            <dbReference type="Rhea" id="RHEA-COMP:13338"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13340"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136798"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[sulfur-carrier protein ThiS]-C-terminal Gly-Gly-AMP + AH2 + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] = [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH + A + AMP + H(+) + L-cysteinyl-[cysteine desulfurase]</text>
            <dbReference type="Rhea" id="RHEA:43340"/>
            <dbReference type="Rhea" id="RHEA-COMP:12157"/>
            <dbReference type="Rhea" id="RHEA-COMP:12158"/>
            <dbReference type="Rhea" id="RHEA-COMP:12908"/>
            <dbReference type="Rhea" id="RHEA-COMP:12910"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:90618"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ThiI family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.4" evidence="6"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_143"/>
    <dbReference type="EnsemblBacteria" id="BAD04228">
        <property type="protein sequence ID" value="BAD04228"/>
        <property type="gene ID" value="PAM_143"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_143"/>
    <dbReference type="eggNOG" id="COG0301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037952_4_0_14"/>
    <dbReference type="OMA" id="SMPEFCG"/>
    <dbReference type="OrthoDB" id="773697at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-175-MON"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004810">
        <property type="term" value="F:tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140741">
        <property type="term" value="F:tRNA U4 sulfurtransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01712">
        <property type="entry name" value="ThiI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00021">
        <property type="entry name" value="ThiI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020536">
        <property type="entry name" value="ThiI_AANH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003720">
        <property type="entry name" value="tRNA_STrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02568">
        <property type="entry name" value="ThiI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00342">
        <property type="entry name" value="TIGR00342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="THUMP" evidence="8">
        <location>
            <begin position="66"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="192"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="434" mass="49724" checksum="A6B1BFD1B6790F68" modified="2004-07-05" version="1">MRNFMYQKKILIRFGELFLKGKNKKAFINTLRQLLQNKIKDLCNVQMYFKHDYAYLEYIYDASLEKEILKRLSYVSGISSFVVVSQASRQLDDIVQKACLLLQEKITKNTSFKIETTRKDKSFALKSLELTQQIAPLILKQFEGKLIVDVKNPQVILHVSIRKENTYLYLKSDETQALGGFPVSSGGGGTVLMSGGIDSPVAAYLAMKKGITVELLHFESSPLTPLESIQKVIDLAKVLSRYAFGNQIKLHLVPFRYLQETITKTVLDSYIINVMRRMMYRLASQFAFQKNHLCLINGESVGQVASQTLESMQTTTQVTSMTILRPLVTMDKNEIIKIAKQIDTFDISIRAFHDCCTLYLPQNPTTKPTILKAKREEQKIDYFPLLNDALQNTITLNIDQHLQFNICDYGFFDVKEAIKHFCEQNPEQTIVSQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR78</accession>
    <name>Q6YR78_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rplM</name>
        <name evidence="5" type="ordered locus">PAM_138</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_138"/>
    <dbReference type="EnsemblBacteria" id="BAD04223">
        <property type="protein sequence ID" value="BAD04223"/>
        <property type="gene ID" value="PAM_138"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_138"/>
    <dbReference type="eggNOG" id="COG0102">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082184_2_2_14"/>
    <dbReference type="OMA" id="DFVVIIN"/>
    <dbReference type="OrthoDB" id="1822215at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-170-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="152" mass="17189" checksum="CA1BB0305A4E87F9" modified="2004-07-05" version="1">MTEQLQPKNNQKTLMANKTTVKPKWHLVDAKGKTLGRLATKVASILKGKHKTHYTPHVDNGDYVIVVNAAYIHLTGKKWQQKTYYKHSGYPGGLTKVVASEMMRKFPTRMVEKAILGMVPHTKLGSQIGKKLFVYAEQNHNHQAQQPESLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR79</accession>
    <name>Q6YR79_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DJ-1_PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_137"/>
    <dbReference type="EnsemblBacteria" id="BAD04222">
        <property type="protein sequence ID" value="BAD04222"/>
        <property type="gene ID" value="PAM_137"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_137"/>
    <dbReference type="eggNOG" id="COG0693">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_2_14"/>
    <dbReference type="OMA" id="TSYPAMK"/>
    <dbReference type="OrthoDB" id="1421548at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-169-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="4"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="180" mass="19851" checksum="BAD13FD481B8AA7F" modified="2004-07-05" version="1">MKGLLVLYDRFEDCEALVTRALLNRVALPLTTATLNPQLEVMSSSGLCVKADANLATINPLEYDFLVIPGGPYVAQIIEKETFLLKLIQKFVDANKVIGAICAAPMFLGKLDLLKNHPFTCFPSCNHFIEGTYLPDQKAVISDKFVTSRSPITVFDFVFALVEVLKGKAFAFAFKNSLNV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-01-15" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR90</accession>
    <name>MNMA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="1">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mnmA</name>
        <name type="synonym">trmU</name>
        <name type="ordered locus">PAM_125</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR90"/>
    <dbReference type="SMR" id="Q6YR90"/>
    <dbReference type="STRING" id="262768.PAM_125"/>
    <dbReference type="PRIDE" id="Q6YR90"/>
    <dbReference type="EnsemblBacteria" id="BAD04210">
        <property type="protein sequence ID" value="BAD04210"/>
        <property type="gene ID" value="PAM_125"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_125"/>
    <dbReference type="eggNOG" id="COG0482">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035188_1_0_14"/>
    <dbReference type="OMA" id="AVCTGHY"/>
    <dbReference type="OrthoDB" id="1054741at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-157-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000009549" description="tRNA-specific 2-thiouridylase MnmA">
        <location>
            <begin position="1"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with target base in tRNA" evidence="1">
        <location>
            <begin position="102"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="1">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="1">
        <location>
            <begin position="316"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="1">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="1">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="1">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Alternate" evidence="1">
        <location>
            <begin position="107"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <sequence length="378" mass="43142" checksum="D7B919502E604BE3" modified="2004-07-05" version="1">MTKVVVGLSGGVDSAVAAFLLKKQGYLVEAVFMRNWDSNLNFDIQGNPTLNDICSQELDYKDSLKVSEQLGIKLHRVDFIEEYWQKVFMSFIKAFENNLTPNPDILCNNEIKFRAFIEYATTKLAPQYIAMGHYANIIYETSSDQKLVPRLACAVDQNKDQTYFLSQLTTKQLQNILFPLGNLTKQEVRQIALENNLINATKKDSTGICFIGERNFFQFLSNYLPAQKGDIKTLDGTFLAHHKGVMYYTIGQRKNLGLGDVPSQKPWFVVGKHLPTNTLYVEQGSTHPYLYSDKALIGDIVWRGKKTNLHLQAKMRYRQPNQDVILTWLDQNNLEIHYPQTIKAVTPGQICAFYDKNICCGAGVIKEVYFQGTKRLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRA5</accession>
    <name>Q6YRA5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_110"/>
    <dbReference type="EnsemblBacteria" id="BAD04195">
        <property type="protein sequence ID" value="BAD04195"/>
        <property type="gene ID" value="PAM_110"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_110"/>
    <dbReference type="HOGENOM" id="CLU_1223735_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-142-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="226" mass="25015" checksum="765A2222BE4F55D3" modified="2004-07-05" version="1">MKGVESTVNTSDQGVTAKNNRTYEHTFKLPPVMQNDTGKKSYTKTLEELQKSNQAYKEYTEKGVDDKYKDGTLKYKDLHNNPSVLNSNGTVHKEPYKFTFNLQQVYSLENTLEETETVNGTTTKKTKTLLAKLLELSNLNASKDLYSQGNLALIVYYKLVDKDGNTESSNTGTVVQSAKVPLKPRALKVSNKGQTNFAGAGMRQTQAVTQTQAQGQGNNSRSNPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRB4</accession>
    <name>Q6YRB4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_101"/>
    <dbReference type="EnsemblBacteria" id="BAD04186">
        <property type="protein sequence ID" value="BAD04186"/>
        <property type="gene ID" value="PAM_101"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_101"/>
    <dbReference type="eggNOG" id="COG3481">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056349_3_0_14"/>
    <dbReference type="OMA" id="LWYLDNI"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="86"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="244" mass="28326" checksum="214BB229EFB55874" modified="2004-07-05" version="1">MMNQTYNLAYNVLDMQTLYETYLAFYECAPISFAIVKDELENYLHKIKNKVLKQITYNLYCKNKNKFLISKAALKIHHNYYGGLGYHTLTMLKMAESLLKIYPFLNNDLLFAGTILHDMEKIKELDLEQKNYTPKGLLLGHLVISACEVEKEAQLLGFQDKEEVLLLKHMLISHHGLLEHGAAKRPQIGEALLLWYLDNIDCKLTSLQEFLQKTTTQTFTEPIPVLERKGFYKSLDLDQNNDDE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-01" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRD0</accession>
    <name>TRHO_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine(34) hydroxylase</fullName>
            <ecNumber evidence="1">1.14.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA hydroxylation protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trhO</name>
        <name type="ordered locus">PAM_085</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + O2 + uridine(34) in tRNA = 5-hydroxyuridine(34) in tRNA + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:64224"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrhO family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04170" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04170.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRD0"/>
    <dbReference type="SMR" id="Q6YRD0"/>
    <dbReference type="STRING" id="262768.PAM_085"/>
    <dbReference type="EnsemblBacteria" id="BAD04170">
        <property type="protein sequence ID" value="BAD04170"/>
        <property type="gene ID" value="PAM_085"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_085"/>
    <dbReference type="eggNOG" id="COG1054">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038878_1_0_14"/>
    <dbReference type="OMA" id="CDTHTNC"/>
    <dbReference type="OrthoDB" id="684577at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-114-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00469">
        <property type="entry name" value="TrhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="PTHR43268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000161490" description="tRNA uridine(34) hydroxylase">
        <location>
            <begin position="1"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="129"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="1">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="308" mass="35752" checksum="649745F35937E324" modified="2006-06-27" version="2">MTQTSNSQYLVILYYQYAPIKDPQTFRDQHFKYCESIGLLGRIIVAQEGINGTLSGPEEQIHKYMDQLKQDPRFCNTVFKMETVEAHVFPRLSIKVKPELVNLSLQENVDLTKDKGAYLAPQEFLQALQEKDTLILDARNDYEYDLGHFRNAVNPNIRHFRDLPNWVKQNTHLLKDKKIVTYCTGGVRCEKFSTFLKKEGFDDVYQLEGGIISYGKHPETQGALWDGQMYVFDQRIAVPVNQKEHVIVGKDYFDGTPCERYINCSNPQCNKQILCHEYNEHKYLGACSDKCSNHPQNRYLKKHNNPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRD1</accession>
    <name>Q6YRD1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_084"/>
    <dbReference type="EnsemblBacteria" id="BAD04169">
        <property type="protein sequence ID" value="BAD04169"/>
        <property type="gene ID" value="PAM_084"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_084"/>
    <dbReference type="HOGENOM" id="CLU_2207355_0_0_14"/>
    <dbReference type="OMA" id="CYNSETI"/>
    <dbReference type="OrthoDB" id="1815826at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-113-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="107" mass="12490" checksum="D65CD1672B7BE2FA" modified="2004-07-05" version="1">MQIKNIYLRPHNSQTFPQQIKTYIKTNINPSFWGFVSNYPCYNSETIQTYPCLLCRIKDASSDLLGVFFDGGTRTASFKGEIKYSLDDLKQMLNGAQNMYIFWKERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRE1</accession>
    <name>Q6YRE1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replicative DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dnaB</name>
        <name evidence="2" type="ordered locus">PAM_074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_074"/>
    <dbReference type="EnsemblBacteria" id="BAD04159">
        <property type="protein sequence ID" value="BAD04159"/>
        <property type="gene ID" value="PAM_074"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_074"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_546093_0_0_14"/>
    <dbReference type="OrthoDB" id="497256at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-98-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="1">
        <location>
            <begin position="192"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="499" mass="58587" checksum="4988DC15CCEF062C" modified="2004-07-05" version="1">MLTNEQKALKQIISYMNQNKADQLSFYFQLIDPQSFLDKKNTKIFQALKYLTLNQTNNHPFDKIKSQTEIIKELLTYLQTHFPQDHFTKESLSFLSDDVNEENNLDFLANLKHTYTQEKLFQQLLKIISPSFENKDPYHKHLYYQEIFDKLRKFMSFIPHPSDNTLLTLNQMASCHPEFFKSDQQAQAKQKIQEEYYRLSETFKGLNQATKGFKKGQIITIGGYTGLGKTTFVYNLLLDIAKTKHQESSYYPHMLVFSYEMTMEENLSRLLAHQTQIPLDVILDKNWEDSNITTHTYMERMNNAKKFFSQLNLSFSYDQVKKIDYIIDLVYRFSLEQKVEIIVIDHLQITKASNHLENDRLAIDEIMTKLKQLAMELNIVIIILSQFSRDTYSHYQGKSPEITALKGSGGIETNSDIVLMMSEFQPKLSKDQEKPLNIYNQNCNQLYLASKNNESQKIIELSIKKNRSGTKKNLVYHFEMTTQTFQEIGYILPYPLESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRE5</accession>
    <name>Q6YRE5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04155">
        <property type="protein sequence ID" value="BAD04155"/>
        <property type="gene ID" value="PAM_070"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_070"/>
    <dbReference type="HOGENOM" id="CLU_1439732_0_0_14"/>
    <dbReference type="OMA" id="MNQVIAM"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="190" mass="22601" checksum="D019E0CB6EF3081C" modified="2004-07-05" version="1">MIKLQNQFKIISIYLFTFLGLLFMTNNYQVMAMDNNDGISENNSVVDNHIDEYNTFRNLLLTQGRISQQLINALFNHSSVTEINFLLNQIQQVHQQIITYQQRQLNNQEQMLRNFDNNMTRVQLEREYLLLTQEMISAINNTPLYASEEQINTLRNIQTRIDQNQRQINIIRNQIQNNQNQPNNHKKTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRF2</accession>
    <name>Q6YRF2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">himA</name>
        <name evidence="2" type="ordered locus">PAM_063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04148">
        <property type="protein sequence ID" value="BAD04148"/>
        <property type="gene ID" value="PAM_063"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_063"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_3_14"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-84-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="96" mass="10973" checksum="0A2D0AEA01402ECE" modified="2004-07-05" version="1">MTKKELIKKTAEVNKTSISKTEEFYHIFENTLIKAITTNEEVVLSPQIGKFQLKPRKAYIGRNPKTKKKLKIPAKTVVAFKLSKSIKDKAKTLILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-06-17" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRF8</accession>
    <name>Q6YRF8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04142">
        <property type="protein sequence ID" value="BAD04142"/>
        <property type="gene ID" value="PAM_057"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_057"/>
    <dbReference type="HOGENOM" id="CLU_893824_0_0_14"/>
    <dbReference type="OMA" id="KECEWIL"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="311" mass="37223" checksum="C322028F6AF31F35" modified="2004-07-05" version="1">MINMKFLDFIFDNPEYFNKLLKKSHNHKNQKINKLMQKHVSNKTDKIVSYKMIFIKFFILNLFCLLSGLIIYQLLSHYHSTLYSFLQTKITNIKELILFLIGFKLIIILICCFYKLSLYYWNCFLPIALHLMVILVGFLYAALFCFYRFYGKQYLDFSPFIQHLIPLIPLISLLITILILVFITVLYKINKIKVYPGFIKVLKIFFLISFIGEIICFSLYCYHNYFSNFFFLIILIFLSLITFIIGILRWVYVLHQLDNFAKNAKNKVLAKECEWILVNFLWLSSMEVFCSIFELFIYVITYLGNIKNDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRH3</accession>
    <name>Q6YRH3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dam</name>
        <name evidence="6" type="ordered locus">PAM_042</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="7520">
        <property type="entry name" value="M.PhsOYORF42P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04127">
        <property type="protein sequence ID" value="BAD04127"/>
        <property type="gene ID" value="PAM_042"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_042"/>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063430_5_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="219" mass="26634" checksum="8CD104C0E514FDF6" modified="2004-07-05" version="1">MWKQSFQNTHHFVNKVKAIENYIYQYCNQKNQKQAFKHLLNQYNQNVKKRKILTRSAIFYVLNKYAFRGITRYDKQSNLKTNFGYKPKQKTPIINLNELVTFQRHFQKKKHVLYCTDFRKVIANSQQGDFLFIDPPYYYEGIKDKDFYQKPFYFTDHQQLALELHQTTKRGVKWLYTNYETTPILHLFSNCNIIKTKTTTSHYLTNKKIHQEIIIKNYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="115" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRI5</accession>
    <name>Q6YRI5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation transport ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mgtA</name>
        <name evidence="9" type="ordered locus">PAM_030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_030"/>
    <dbReference type="EnsemblBacteria" id="BAD04115">
        <property type="protein sequence ID" value="BAD04115"/>
        <property type="gene ID" value="PAM_030"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_030"/>
    <dbReference type="eggNOG" id="COG0474">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_1_1_14"/>
    <dbReference type="OMA" id="RRFLTYH"/>
    <dbReference type="OrthoDB" id="178322at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-39-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="708"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="735"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="787"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="814"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="854"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="885"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="9"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="920" mass="102143" checksum="1B20191B3F948881" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-03-07" modified="2022-08-03" version="108" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRJ6</accession>
    <name>SYV_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Valine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Valyl-tRNA synthetase</fullName>
            <shortName evidence="1">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">valS</name>
        <name type="ordered locus">PAM_018</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="frameshift">
            <sequence resource="EMBL-CDS" id="BAD04103" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04103.1"/>
        <property type="status" value="ALT_FRAME"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRJ6"/>
    <dbReference type="SMR" id="Q6YRJ6"/>
    <dbReference type="STRING" id="262768.PAM_018"/>
    <dbReference type="EnsemblBacteria" id="BAD04103">
        <property type="protein sequence ID" value="BAD04103"/>
        <property type="gene ID" value="PAM_018"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_018"/>
    <dbReference type="eggNOG" id="COG0525">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_0_2_14"/>
    <dbReference type="OMA" id="FATKLWN"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0175">Coiled coil</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000224522" description="Valine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="849"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region">
        <location>
            <begin position="522"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="525"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="882" mass="103099" checksum="B17DE16AE8C0900A" modified="2006-03-07" version="2"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-10-31" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRK2</accession>
    <name>RL9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName>50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">rplI</name>
        <name type="ordered locus">PAM_012</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04097" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04097.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRK2"/>
    <dbReference type="SMR" id="Q6YRK2"/>
    <dbReference type="STRING" id="262768.PAM_012"/>
    <dbReference type="EnsemblBacteria" id="BAD04097">
        <property type="protein sequence ID" value="BAD04097"/>
        <property type="gene ID" value="PAM_012"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_012"/>
    <dbReference type="eggNOG" id="COG0359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3887">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018278_0_0_14"/>
    <dbReference type="OMA" id="STCELVT"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-17-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000258475" description="50S ribosomal protein L9">
        <location>
            <begin position="1"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Unknown">
        <location>
            <begin position="1"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="50S ribosomal protein L9">
        <location>
            <begin position="700"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="849" mass="96795" checksum="778BA790A63B64C7" modified="2006-10-31" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="113" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRK4</accession>
    <name>Q6YRK4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_010"/>
    <dbReference type="EnsemblBacteria" id="BAD04095">
        <property type="protein sequence ID" value="BAD04095"/>
        <property type="gene ID" value="PAM_010"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_010"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OMA" id="DRPVANA"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-15-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="114" mass="12778" checksum="8C60ACB4DE73C733" modified="2004-07-05" version="1">MINKVILVGRITKDPELKNTNSGTYVVKFTLAVNRIVSASSEKKTDFINCTVFGKQAENLEKYISKGALIGVEGNIRVETWEKDGVTNWQTSVVCNNVQFLESKKNPDNAYDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRK9</accession>
    <name>Q6YRK9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Membrane-associated phospholipid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgpB</name>
        <name evidence="7" type="ordered locus">PAM_005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_005"/>
    <dbReference type="EnsemblBacteria" id="BAD04090">
        <property type="protein sequence ID" value="BAD04090"/>
        <property type="gene ID" value="PAM_005"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_005"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1106282_0_0_14"/>
    <dbReference type="OMA" id="LIQHITW"/>
    <dbReference type="OrthoDB" id="1334297at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-8-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="PAP2_3" evidence="6">
        <location>
            <begin position="96"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="251" mass="30373" checksum="FF55AD9B0CD9B887" modified="2004-07-05" version="1">MEKQTLQRNNLKKKETNSKNKYLKKYILWFLFIVLIQHITWFGSLYIIEKNKNGFFKTIILIKEYGNEETNNYWVKILNLNINGSSGFPSWEFSKYFIYIYIISCWWWFLISPYLIYKHLDKKIIFQLFISYFIILAISFILFFVFPVQMLDKFLFKENKSFVDFLIQNLYKYDYLHLNNLPSFHVSLSWLCYIGFRQKNKKKIPKILNYGQLFCAILVFISTFVLKQHYIVDGIIAIILVETTFFLVGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRL0</accession>
    <name>Q6YRL0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04089">
        <property type="protein sequence ID" value="BAD04089"/>
        <property type="gene ID" value="PAM_004"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_004"/>
    <dbReference type="HOGENOM" id="CLU_2437953_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-7-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="90" mass="10688" checksum="1DB213DFF23EBDDA" modified="2004-07-05" version="1">MQNETFIPFQELKDAGYDAKDFKNAKYPAKYLKNNGFSLKELMNAEYRSFDLKIAGYTLEEIKECLTNHPNSYYNIQNIEQNYYTENVHN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-02-16" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>P60351</accession>
    <name>TRUA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="1">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">truA</name>
        <name type="ordered locus">PAM_229</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P60351"/>
    <dbReference type="SMR" id="P60351"/>
    <dbReference type="STRING" id="262768.PAM_229"/>
    <dbReference type="EnsemblBacteria" id="BAD04314">
        <property type="protein sequence ID" value="BAD04314"/>
        <property type="gene ID" value="PAM_229"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_229"/>
    <dbReference type="eggNOG" id="COG0101">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014673_0_1_14"/>
    <dbReference type="OMA" id="FLYGMVR"/>
    <dbReference type="OrthoDB" id="1075262at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-275-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000057424" description="tRNA pseudouridine synthase A">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <sequence length="243" mass="28463" checksum="5585FDF74CF569BE" modified="2004-02-16" version="1">MQHFFYKLILSYDGTCYYGYQKQPQKITVQQTFEKALKKMTHQNIPTFAASRTDKGVHSQGQTLHFQTTFFLKPTHFQKTLNYLLPPDIRVRQMNFATPNFHARYSAKSKIYQYVFSKKPLNAFNHHFQIFADKLYFDKITKALKFIEGTHNFFAFTSETQPKNFSKTIFQAFLKETSHKYILVFHGNGFLKYMIRFLVGSLIEIGKNKLSLEQFQAMLLGNTTKKATLLAPSKALVLKKIFY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-04-13" modified="2022-05-25" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>P60823</accession>
    <name>PLSY_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycerol-3-phosphate acyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Acyl-PO4 G3P acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Acyl-phosphate--glycerol-3-phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">G3P acyltransferase</fullName>
            <shortName evidence="1">GPAT</shortName>
            <ecNumber evidence="1">2.3.1.275</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Lysophosphatidic acid synthase</fullName>
            <shortName evidence="1">LPA synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">plsY</name>
        <name type="ordered locus">PAM_436</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:34075"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="2.3.1.275"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Probably interacts with PlsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PlsY family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.275" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P60823"/>
    <dbReference type="SMR" id="P60823"/>
    <dbReference type="STRING" id="262768.PAM_436"/>
    <dbReference type="EnsemblBacteria" id="BAD04521">
        <property type="protein sequence ID" value="BAD04521"/>
        <property type="gene ID" value="PAM_436"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_436"/>
    <dbReference type="eggNOG" id="COG0344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081254_7_2_14"/>
    <dbReference type="OMA" id="AQWVILT"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01043">
        <property type="entry name" value="PlsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00023">
        <property type="entry name" value="TIGR00023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword id="KW-1208">Phospholipid metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000188417" description="Glycerol-3-phosphate acyltransferase">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01043"/>
        </source>
    </evidence>
    <sequence length="172" mass="18834" checksum="251EDFE8D24C1138" modified="2004-04-13" version="1">MENLSFLFLFLFFYILGSIPTGLVIGKLVQQKDLRNTGSGNIGATNALRVLGKKWGILVFLLDFCKGFVPLTICLHFSKFWLTEPSTKTFLQPNPTIKISLLAISPILGHMFSLFNKFKGGKAIATSVGIITAFNPLIGISGIIFFAIFLRLFGYASLASIIASTLVNVFYG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-07-05" modified="2022-08-03" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>P62417</accession>
    <name>PGK_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="1">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pgk</name>
        <name type="ordered locus">PAM_174</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P62417"/>
    <dbReference type="SMR" id="P62417"/>
    <dbReference type="STRING" id="262768.PAM_174"/>
    <dbReference type="EnsemblBacteria" id="BAD04259">
        <property type="protein sequence ID" value="BAD04259"/>
        <property type="gene ID" value="PAM_174"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_174"/>
    <dbReference type="eggNOG" id="COG0126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025427_0_2_14"/>
    <dbReference type="OMA" id="DMIFDIG"/>
    <dbReference type="OrthoDB" id="462069at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-213-MON"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0324">Glycolysis</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000145979" description="Phosphoglycerate kinase">
        <location>
            <begin position="1"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="20"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="58"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="354"/>
            <end position="357"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <sequence length="398" mass="43522" checksum="11D26EC9F797615C" modified="2004-07-05" version="1">MTKSLTNMNITNKKVLLRADLNVPLENSVITDDNRIKAILPTLKYLVQQKAKVIIFSHLGRVKTEADKAHFSLQVVAEKIAFYLQQKLKFVPETQGNTLNQAVGQMLPGDVLVVQNTRFEDVPFKKESKNDPELGKYWASLGDVFVNDAFGTCHRTHASNVGIATYIKEKCFGFLVEKEISFLKKIVQTPQRPLVAVLGGSKVSDKIGVIRSLLQKVDVLLIGGGMSYTCLKAKCFNIGTSLLEADKIPLVKELLASPEGKKIVLPKDFVCGKEFSPTTQAAVYSYDNISDDVMGLDIGPQTIELFKTYLQTAQTVVWNGPVGVFEFEQFSKGTKALAETISNLSPNTTTIIGGGDSAAAVFKFGLDQNFSHISTGGGAFLEFLEGKPMPGLACMEKL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-10-11" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPI4</accession>
    <name>RL35_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmI</name>
        <name type="ordered locus">PAM_743</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPI4"/>
    <dbReference type="SMR" id="Q6YPI4"/>
    <dbReference type="STRING" id="262768.PAM_743"/>
    <dbReference type="EnsemblBacteria" id="BAD04828">
        <property type="protein sequence ID" value="BAD04828"/>
        <property type="gene ID" value="PAM_743"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_743"/>
    <dbReference type="eggNOG" id="COG0291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169643_3_1_14"/>
    <dbReference type="OMA" id="GHAYKNH"/>
    <dbReference type="OrthoDB" id="2046660at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-898-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_L35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000177393" description="50S ribosomal protein L35">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <sequence length="68" mass="7871" checksum="16EA44B47FD670C5" modified="2004-07-05" version="1">MIKVIKKKSHSGLKKRIKISKKKKLLRGHAYKNHLAASKTTKQNRQLRGVTCVKLCDYNRIKTLIRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPJ1</accession>
    <name>Q6YPJ1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Na+-driven multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">norM</name>
        <name evidence="2" type="ordered locus">PAM_734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_734"/>
    <dbReference type="EnsemblBacteria" id="BAD04819">
        <property type="protein sequence ID" value="BAD04819"/>
        <property type="gene ID" value="PAM_734"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_734"/>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_558874_0_0_14"/>
    <dbReference type="OMA" id="GPIIGQN"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="464"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="499" mass="56795" checksum="5F399E4E8A36FD96" modified="2004-07-05" version="1">MFDPTQTLDGGFFVVKTKATTQILINEKRNRKFLLEGNLWKVIFYFTFPIIIYWIFQNASDAIDLFILKRNQISDNQLTFVSRVHIFKGILVPFGISIATGGVILVGRAYGQNNVNKMHLYLAKTFVLSILTGFILVFLCIFVFKSFIATNILKISQNAIENNEGIKYYNLIILSLVCIIINTVFLSLERAKGNNKIALFLNILNASAKIIFSFVLFHYWNSSMVSLALATLISNGIVTLFALWFLFFDSKNPFRIILSKISFDKEFLKKLSKLAIPVCASISIYSVGKLIVSIIVKEWYGDPQGISSSQIGANLALAVTINNVFYNALNSFSDSQNAIISQNLGHNNLNRVFEAFKKIIFCMCVLALIGSLINIFGYKLILPLFHDSPWEKIPTLEQDVFRTLLFFETTSLWLSCGSIIMFNFLLAFKRVGPSVYLNFLRTLIRIFFIVLFSKHFLNQGVMGVGLSIFLSNFICFIITLLIFSTFYLKLKRDKTFEQD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-11-22" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPJ3</accession>
    <name>SP5G_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative septation protein SpoVG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">spoVG</name>
        <name type="ordered locus">PAM_732</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be involved in septation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SpoVG family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPJ3"/>
    <dbReference type="SMR" id="Q6YPJ3"/>
    <dbReference type="STRING" id="262768.PAM_732"/>
    <dbReference type="EnsemblBacteria" id="BAD04817">
        <property type="protein sequence ID" value="BAD04817"/>
        <property type="gene ID" value="PAM_732"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_732"/>
    <dbReference type="eggNOG" id="COG2088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103669_2_1_14"/>
    <dbReference type="OMA" id="KDVAHPI"/>
    <dbReference type="OrthoDB" id="1871825at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-887-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00819">
        <property type="entry name" value="SpoVG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007170">
        <property type="entry name" value="SpoVG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036751">
        <property type="entry name" value="SpoVG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38429">
        <property type="entry name" value="PTHR38429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04026">
        <property type="entry name" value="SpoVG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160537">
        <property type="entry name" value="SSF160537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0717">Septation</keyword>
    <feature type="chain" id="PRO_0000157204" description="Putative septation protein SpoVG">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00819"/>
        </source>
    </evidence>
    <sequence length="99" mass="11411" checksum="C328A423496A7DEF" modified="2004-07-05" version="1">MKVTDVKIRKINGESRLRGVSSITFENQFVVNDIRIIEGERGIFIAMPSRKTSKGNFRDIAHPINSETRQLIENCIKTKYQDLLDNPPQEEDFSQNSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPL4</accession>
    <name>Q6YPL4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_711"/>
    <dbReference type="EnsemblBacteria" id="BAD04796">
        <property type="protein sequence ID" value="BAD04796"/>
        <property type="gene ID" value="PAM_711"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_711"/>
    <dbReference type="HOGENOM" id="CLU_1382905_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-866-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="197" mass="23091" checksum="F3F71EBD2BB8DB26" modified="2004-07-05" version="1">MLTNQSLHYNVFLSNLYKSINAIKDCNEFKDVCSNLPIKREAQFAFHKNTIKLKFQPLLDKINSFLQNNKKEIILIPETINPNQTQNAMSKEQFINLIKGKLNNLESIFNPYYIVPEALPSNNILDIFATFKETYNGFNNGFHIDNCNEQESINTLENMLMNFKKIKNYQNPSNELETNFFQSYFKLLNDIDQIKKT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-09-27" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPM0</accession>
    <name>GRPE_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">grpE</name>
        <name type="ordered locus">PAM_705</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPM0"/>
    <dbReference type="SMR" id="Q6YPM0"/>
    <dbReference type="STRING" id="262768.PAM_705"/>
    <dbReference type="EnsemblBacteria" id="BAD04790">
        <property type="protein sequence ID" value="BAD04790"/>
        <property type="gene ID" value="PAM_705"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_705"/>
    <dbReference type="eggNOG" id="COG0576">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057217_5_2_14"/>
    <dbReference type="OMA" id="YAYEKIA"/>
    <dbReference type="OrthoDB" id="1415610at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-858-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <feature type="chain" id="PRO_0000113829" description="Protein GrpE">
        <location>
            <begin position="1"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="247" mass="28973" checksum="99AEF8D4F086B964" modified="2004-07-05" version="1">MFLEKDQDNLDNLETQAKELHKDCKECKNCQKEETKTTNKDNQKEDETVKNQSNQSNQSNQTKQTNTKQQKHQPKENSHLQITKLQTQIKELQQQLTQQKKSFDEELLKNQAELINFKKRAQTQKANELKYASSNFITNLLMPLEQLEKVIDMPTQNELLQKYLLGFKLLQQQIKKVLQDEGVEEIEALNKPFDPALHHALETVCDPKKPDKTNLAVLQKGYLYKKRILRPTLVKVNEWSDKNDKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="110" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPP0</accession>
    <name>Q6YPP0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA primase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dnaG</name>
        <name evidence="9" type="ordered locus">PAM_685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_685"/>
    <dbReference type="EnsemblBacteria" id="BAD04770">
        <property type="protein sequence ID" value="BAD04770"/>
        <property type="gene ID" value="PAM_685"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_685"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620870_0_0_14"/>
    <dbReference type="OrthoDB" id="308401at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-836-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0639">Primosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="302"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="441" mass="52167" checksum="13A0A85108F184FA" modified="2004-07-05" version="1">MNYQNKIKHIQTQFPMSVLLKKLNIISPNFNIKYRFPCPIHQGQNPTCCQITSDNKIHCWKCCCDFDIIDVYMEIRGIKTFNLALERINNFMQTQEFKTLIEQQNLTPNSLTNPFKYQYHPKNASNPTDEKEINAKKTQLFKEISPLFNQIRDYYNYLLTSNRNNESHLGLEYLTQKRKLNLKTIQEFKLGYAPLSDKPLSFRLINYCKKKNIDITKLVEYGFIKEKINQKDAKYYHDTFHGSVIIPIENGYKKTFHFYQNNFREVSYFQPKYKSLNNFSQTNTFHFSYRFFEALPYIKQTKTIIIHEGFFDVISCYQNNIKNVAGLICVTQLLSQSQLEILKKENIKVIIALDNDETGQKRSEALGIQLKEANIIYEIRRILPPYDKTCKDVDDLLRQFGKQAYQKCFLDPYITYEEAKKKIIVDLAVHFFGQDKVEIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPP7</accession>
    <name>Q6YPP7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Signal recognition particle GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ffh</name>
        <name evidence="10" type="ordered locus">PAM_678</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_678"/>
    <dbReference type="EnsemblBacteria" id="BAD04763">
        <property type="protein sequence ID" value="BAD04763"/>
        <property type="gene ID" value="PAM_678"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_678"/>
    <dbReference type="eggNOG" id="COG0541">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009301_6_0_14"/>
    <dbReference type="OMA" id="DTAGRHK"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="9">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="426" mass="47369" checksum="9BC3D1A8B264F4DE" modified="2004-07-05" version="1">MQDIKVSLVEADVHLQVIDKFNEIIEKKTLKQEVLKGLNPKEHIIKIVNETLIQILGSTRADLTFKPNCNLDTLMLIGLQGSGKTTTVGKLALWLRKKNSKKVLLVACDIYRPGAVEQLKVIGKQINIDVFSKPDTAVLDIVDAGLKHALQEGYDAVIIDTAGRLDIDETMMQELQQIKAKANPSEILLVVDCLSGQQSANIAQSFHNQVGATGVILTKMDADTKGGAALSVRAMTDLPLKFVSSSETIDSLDPFNPDRMASRLLGMGDILTLIETVTDKIDPHQSKQMMEKLFDDSYNYYDFQKQLKTLKKIGSVSKLLSFIPGLGGKMKQLSASLGDDGFNKFEVLIQSMTKQEKKNPQLIALSGRRRQRIAKGSGNQLSDVNKLITLLEQQKKLAKQMQHFDDQDLDKLQNDPMAFFRDMNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPQ3</accession>
    <name>Q6YPQ3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA replication protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dnaC</name>
        <name evidence="2" type="ordered locus">PAM_672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_672"/>
    <dbReference type="EnsemblBacteria" id="BAD04757">
        <property type="protein sequence ID" value="BAD04757"/>
        <property type="gene ID" value="PAM_672"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_672"/>
    <dbReference type="eggNOG" id="COG1484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077384_1_0_14"/>
    <dbReference type="OMA" id="SENMTPW"/>
    <dbReference type="OrthoDB" id="1792718at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-821-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IstB_IS21" evidence="1">
        <location>
            <begin position="96"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="272" mass="32280" checksum="11706EDD6641D123" modified="2004-07-05" version="1">MEFSDIKIKIRKMIAQCEETKNLDISDDELPVIYHYLLTKDQENEYGNRQKIKTNPLRVVWVPTVKSQALYFKEHWQSQNELFDSSINFDAHLVMQFVVDNDSKQKALKEMKQIIKHFEKSTKGFYLSGSFNTGKTIFLKKTAYELIQKQISVIFLFMPDITRKFRNFLYNNTLETRLQQLKNVKCLILDDLGSENMTPWFRDEILLPLLYDRAEKKLPLFISSNLTFNELHNYLLHLHGAENANSEVKVYKIIEKIRTLTHFYDFSEKQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPQ7</accession>
    <name>Q6YPQ7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_668</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04753">
        <property type="protein sequence ID" value="BAD04753"/>
        <property type="gene ID" value="PAM_668"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_668"/>
    <dbReference type="HOGENOM" id="CLU_2058987_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-814-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="119" mass="14161" checksum="7270CACD97947C32" modified="2004-07-05" version="1">MFYKLYQKKLSDFSIEEIRDLFFKLYNNDEVHTILLGANSCIEKHPCIYQSNLSLELHRNNISGDDDIDFNNDDYKKLNYKFYTILELLHLGNIDYISQGWNKLGENIKTVKDVLEKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPR7</accession>
    <name>Q6YPR7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflB</name>
        <name evidence="5" type="ordered locus">PAM_658</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_658"/>
    <dbReference type="EnsemblBacteria" id="BAD04743">
        <property type="protein sequence ID" value="BAD04743"/>
        <property type="gene ID" value="PAM_658"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_658"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_16_2_14"/>
    <dbReference type="OMA" id="AFMKREN"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-803-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="126"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="559"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="583"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="598" mass="66957" checksum="1A479959032D70F1" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPS3</accession>
    <name>Q6YPS3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04737">
        <property type="protein sequence ID" value="BAD04737"/>
        <property type="gene ID" value="PAM_652"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_652"/>
    <dbReference type="HOGENOM" id="CLU_959212_0_0_14"/>
    <dbReference type="OrthoDB" id="2121724at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-796-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="286" mass="32480" checksum="3903DD8BA183929D" modified="2004-07-05" version="1">MSKKTNKNSKNQSKNNKSNEIIIKRKNPTPKIIIETQTKKENWLFKIIKTFFNIFKWFIPLLLIGGGFYWTLFKFFPEVLNQINAFTSNAVTKTKILYDKATQPIRKVIEYIYNKLTGNDKDPNHVPSPQNKLGYYLATTLSVIGICLGIGKIGNWLKSRKKKTIKKGTTKAIKKTAPSKLANLGGKALRIGSKALFLVSLASTAYELYQFYREENKTPNPPQQLTNKIENPSTPISQTPSIQQSFNPTIIENEESNITNNNEDKTETTQEEITQEESESGNLNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPS8</accession>
    <name>Q6YPS8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thymidylate_kin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_390</name>
        <name evidence="3" type="ordered locus">PAM_647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_390"/>
    <dbReference type="EnsemblBacteria" id="BAD04475">
        <property type="protein sequence ID" value="BAD04475"/>
        <property type="gene ID" value="PAM_390"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04732">
        <property type="protein sequence ID" value="BAD04732"/>
        <property type="gene ID" value="PAM_647"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_390"/>
    <dbReference type="KEGG" id="poy:PAM_647"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1946601_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-467-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-788-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="1">
        <location>
            <begin position="7"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="126" mass="14665" checksum="2CFC08E1C2DD7294" modified="2004-07-05" version="1">MTKLIVFEGLDGSGKTSLINSLQPQLKTPHQLYQPFGSSSIGKEIRDLFLNFQQVDYLTRFYLSLANMAQIQAELFKNNQLIILDRWLPSAYAYQLFPFSKEKKQLPPLKKIFKLNHETILKNPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPT3</accession>
    <name>Q6YPT3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tra5</name>
        <name evidence="2" type="ordered locus">PAM_642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_642"/>
    <dbReference type="EnsemblBacteria" id="BAD04727">
        <property type="protein sequence ID" value="BAD04727"/>
        <property type="gene ID" value="PAM_642"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_642"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_4_3_14"/>
    <dbReference type="OMA" id="NREHEFH"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="150"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="312" mass="37583" checksum="F8253FBBE2491B32" modified="2004-07-05" version="1">MQKLKQKIKLLQKMIEKIKKIDKKIVFHLVNQFNQTLNLTTILKTIQIKRSTYYYWLKVKNKLKEKEEKYFLQQKRIKALCLHYQYFYGHRKITDLYQKTFNEFITKKKVYLIMKKNDISCRLRIKKIFTYRNLKNNLQIIPNLINQDFMAAKPLQKLFTDITYFKTNQGFLYFSCIIDSFNNQIIASHVSNQQNKDLVLKTIKKLPSLKEPCIIHSDQGKVYQSLKIQQTLIKKGFLISMSRKATPRDNAIIENFFGQMKTILQHQNPFLFQKSPDKMKKLINHFLKFWNNQWILSKLNYSTPSQYIQNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPT8</accession>
    <name>Q6YPT8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase_J_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_637"/>
    <dbReference type="EnsemblBacteria" id="BAD04722">
        <property type="protein sequence ID" value="BAD04722"/>
        <property type="gene ID" value="PAM_637"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_637"/>
    <dbReference type="eggNOG" id="COG0595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008727_3_2_14"/>
    <dbReference type="OMA" id="PWLLMKI"/>
    <dbReference type="OrthoDB" id="580619at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-778-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041636">
        <property type="entry name" value="RNase_J_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17770">
        <property type="entry name" value="RNase_J_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_J_C" evidence="1">
        <location>
            <begin position="470"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="574" mass="65431" checksum="413CA247A020B9E2" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="114" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPU4</accession>
    <name>Q6YPU4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribonuclease</fullName>
            <ecNumber evidence="10">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">PAM_631</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNase HII family. RnhC subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="10"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_631"/>
    <dbReference type="EnsemblBacteria" id="BAD04716">
        <property type="protein sequence ID" value="BAD04716"/>
        <property type="gene ID" value="PAM_631"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_631"/>
    <dbReference type="eggNOG" id="COG1039">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059546_1_0_14"/>
    <dbReference type="OMA" id="TGDYFGP"/>
    <dbReference type="OrthoDB" id="1685277at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-767-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004641">
        <property type="entry name" value="RNase_HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037748">
        <property type="entry name" value="RnhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00716">
        <property type="entry name" value="rnhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="11">
        <location>
            <begin position="120"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="330" mass="37245" checksum="AABC40B08D2C4D50" modified="2004-07-05" version="1">MMSNYSFKLNNNQVATIKKFYYKQLKLSPNKTVAFVIDESLAKIIVYNNGTLLVQGKNTLSIVAFIKKILQMKTVSDNSEIKEVSHSLVKQVPTLKTKSNAGTNSFLPLYNKKTYYLPSIGSDEVGTGDVFGPVIVCCVYLTAKNIVFLQKLGTIAESKKISDEKIMQLAPLIMKEVIYSVKIMMPLEYNQTIKQCNLNKIKALMHNEAIKQTVLKASPNVPVILDQFCFPKNYFNYLQDQKAQNEIYTKIIFETKADSSYFSVAVASVIARYLFLTQIAKLSKQINSKLQLGAGKLVDLQIDLIVKQHGLEILPQIAKCNFKNIVRKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPU5</accession>
    <name>Q6YPU5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diadenosine tetraphosphate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hit</name>
        <name evidence="3" type="ordered locus">PAM_630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_630"/>
    <dbReference type="EnsemblBacteria" id="BAD04715">
        <property type="protein sequence ID" value="BAD04715"/>
        <property type="gene ID" value="PAM_630"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_630"/>
    <dbReference type="eggNOG" id="COG0537">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_3_2_14"/>
    <dbReference type="OMA" id="IAFMDIM"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01277">
        <property type="entry name" value="HINT_subgroup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039384">
        <property type="entry name" value="HINT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="18"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="110"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="153" mass="17623" checksum="C537FDE41E090220" modified="2004-07-05" version="1">MQVYLSKNTFKGVFMSTIFTKIIKKQVPGYLLYEDNLVVAFLDIAQATKGHTLVVPKQEYRDILMMPEDVFAHLFKVVHQISKALMDVFQAQGINLLNNNGKVAGQTVFHYHVHLIPRFDEKEINLVFKNNASLMFPQDYEKVQKAILAHLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="116" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPU7</accession>
    <name>Q6YPU7_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor SigA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpoD</name>
        <name evidence="5" type="synonym">sigA</name>
        <name evidence="10" type="ordered locus">PAM_628</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_628"/>
    <dbReference type="EnsemblBacteria" id="BAD04713">
        <property type="protein sequence ID" value="BAD04713"/>
        <property type="gene ID" value="PAM_628"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_628"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_3_14"/>
    <dbReference type="OMA" id="RRVQREF"/>
    <dbReference type="OrthoDB" id="420193at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-764-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012760">
        <property type="entry name" value="RNA_pol_sigma_RpoD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02393">
        <property type="entry name" value="RpoD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="9">
        <location>
            <begin position="417"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="61"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="5">
        <location>
            <begin position="221"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="190"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="5">
        <location>
            <begin position="245"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="61"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="460" mass="53127" checksum="15102C08BA0A127E" modified="2004-07-05" version="1">MEFDNIIKTLNEQAGSEQKLTSQLIMSFLQNQNIKIPYQQIAQSLKEQGIQIISCETQAAPSLNENPNQNDTQPQTNTTNDDFTDLDSELTNANLENTDDNKDEDNTQDSEEDIQDFDISEEDLISDEKLIELEEDEDEKISKIHSDIKMDDSVRMYLKEIGQIPLLSLAEEQKKSILVFLGKQAKQKLAKHKTKEIELSEEQLQEAHDQIEQARRAKDILVESNYRLVVSIAKRYIGRGILFLDLIQEGNMGLMRAVDKFDYQKGFKFSTYATWWIRQAITRAIADQARTIRIPVHIVETINKMALCTRKLTQKLKKKPTVEELADKMNISAEKIRSIQYIEKKPISLEAPARENEEDETSLGDFISDPNILSPHEYMMKEVTQKLLDEVLENTLTDREEKVLKMRYGLLDGKTHTLEEVGTLFGVTRERIRQIESKALRRLRTPAKQSKLKSLYHNHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPV6</accession>
    <name>Q6YPV6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I restriction-modification system methyltransferase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hsdM</name>
        <name evidence="2" type="ordered locus">PAM_619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_619"/>
    <dbReference type="REBASE" id="7522">
        <property type="entry name" value="M.PhsOYORF619P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04704">
        <property type="protein sequence ID" value="BAD04704"/>
        <property type="gene ID" value="PAM_619"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_619"/>
    <dbReference type="eggNOG" id="COG0286">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2024370_0_0_14"/>
    <dbReference type="OrthoDB" id="791672at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-751-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="122" mass="14000" checksum="F3399A8E5EDC32D7" modified="2004-07-05" version="1">MGEIYMYLIETFVSDNITKKQKSGEFFTPPSVSELLSQIICHKTKNKNITKIYDPFCGSGSLLLKIINHINNNKDFSGQKYKNDIPYYNLKIENGDTLLFPHQSHLEQKYNIIIANPPFGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPX3</accession>
    <name>Q6YPX3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aceF</name>
        <name evidence="7" type="ordered locus">PAM_602</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_602"/>
    <dbReference type="EnsemblBacteria" id="BAD04687">
        <property type="protein sequence ID" value="BAD04687"/>
        <property type="gene ID" value="PAM_602"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_602"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_10_0_14"/>
    <dbReference type="OMA" id="HPCIMAP"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="6">
        <location>
            <begin position="97"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="61"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="394" mass="42900" checksum="54D28B5E9A7426D3" modified="2004-07-05" version="1">MGDQVKEGDVLVKVETDKLDVELTSPVAGKILKRDLNEGEVICVGDTIVLIQEPGDTDADVKKFSSQNPNETAATEKNDTQQAQTSAQTSLPPQKVLATPLVKSLAKELGLDLSTIKGTGVNGKILKVDVQNATNPLQTQPQPTTPFVQEEQIPTPTFATSSQETEVVKISRLRKAIAQKMVLSKGKIPETTLMDEVNITALVTLRKQAKDQAQSQGIKLTFMAFIMKAVAIALQEFPLFNASYDDVKEEVTYKKFINLGVAVDTKDGLIVPNIKDANKLTLLEMAQQLQQVAKATTERKVELNQLQNGTFTITNFGSIDITYGTPVINYPELAILGVGKITKKPVVENSQIVIADMLPLSLAIDHRIIDGADGGRFLKRVKELLNTPTLLLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="127" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPX6</accession>
    <name>Q6YPX6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phnL</name>
        <name evidence="6" type="ordered locus">PAM_599</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_599"/>
    <dbReference type="EnsemblBacteria" id="BAD04684">
        <property type="protein sequence ID" value="BAD04684"/>
        <property type="gene ID" value="PAM_599"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_599"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037418_0_0_14"/>
    <dbReference type="OMA" id="RNGMIGF"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-723-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="305"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="505"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="542" mass="61606" checksum="9FA0132500832554" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPY2</accession>
    <name>Q6YPY2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_593</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_593"/>
    <dbReference type="EnsemblBacteria" id="BAD04678">
        <property type="protein sequence ID" value="BAD04678"/>
        <property type="gene ID" value="PAM_593"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_593"/>
    <dbReference type="eggNOG" id="COG0561">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044146_7_0_14"/>
    <dbReference type="OMA" id="FMINEEC"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-718-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="259" mass="29699" checksum="8F37EB25CADC39E6" modified="2004-07-05" version="1">MKKLFFFDIDQTLYNGKTKEIPSQTTKLLQTLAKKPNNILEIATGRSYKGLSVLKELTSLFKYFVVLNGVITWKATNIVQQTCIPQELVIKLNCQAQKKGIIVLNVSLEEKDITQTTDPDSKSLFDNVMLQKKSHQKQSSFRKTYLQNNLFHPNTSLVVDFLKDFEQLHAYYWKNGVVSLSAKQVNKAYGIQAIMKDHKDCQLICMGDGCNDFEMLQFADIGIVMANNHYETLHKVANLTAPHIEKNALYDFFKDYNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPY8</accession>
    <name>Q6YPY8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04672">
        <property type="protein sequence ID" value="BAD04672"/>
        <property type="gene ID" value="PAM_587"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_587"/>
    <dbReference type="HOGENOM" id="CLU_1863150_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="137" mass="16532" checksum="A652D0DF4FD0EC4C" modified="2004-07-05" version="1">MFLFGLLMLRQELLFKCLFVVCYFVIGLLAFRIYVAVEMFEHKRYYPLKKEEIKKLQIIGVLPKDINQILKKTLLFNFDKLEIIGEAIINSIFYIILLWLFLFIPKNIKWFTNISDFFYYLSLIIISVVWAVIIRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="110" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ06</accession>
    <name>Q6YQ06_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA primase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dnaG</name>
        <name evidence="9" type="ordered locus">PAM_569</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_569"/>
    <dbReference type="EnsemblBacteria" id="BAD04654">
        <property type="protein sequence ID" value="BAD04654"/>
        <property type="gene ID" value="PAM_569"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_569"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620870_0_0_14"/>
    <dbReference type="OMA" id="CEIRRIL"/>
    <dbReference type="OrthoDB" id="1071997at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-687-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0639">Primosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="302"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="441" mass="52331" checksum="2E7B971D264069EC" modified="2004-07-05" version="1">MNYQDKINHIKTNFPMIVLLKKLNIIPPNFNTKYRFPCPIHQGNNPTCCHLTSDNKIHCWKCCKDYDIIDVYMEIRGIKTFNNALEKINNFMKTQEFKNLIQQQTATPNISYKPFKYQFQPNKINNPIDEKEINTTKTQLFKEISPLFNQIRDYYHYLLTTNRNNESHLGLEYLTQKRKLTLETIKEFKLGYAPLSDKPLSFRLVNYCKKQNIDTTKLVEYGFVKEKTNQQNKKYYHDTFHGSIIIPIENGYNKTFHFYQNHFRDTTYFQPKYQSLNNFSQTPTFHFSYRFFEALPYIKKTKTIIIHEGFFDVISCLQHGIKNVVGLICVAQLLSQTQMDILKKEKIKVIIALDNDETGRKRNAALGEQLKEQQIPYEIRRILSPYDKTCKDVDDLLRQYGKEAYQKCFLDPYISYEEAEKKQIVDLAIHFFGEDKVEVMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ07</accession>
    <name>Q6YQ07_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_568"/>
    <dbReference type="EnsemblBacteria" id="BAD04653">
        <property type="protein sequence ID" value="BAD04653"/>
        <property type="gene ID" value="PAM_568"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_568"/>
    <dbReference type="HOGENOM" id="CLU_1609154_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="187" mass="22021" checksum="BAF2B11A0D1B004A" modified="2004-07-05" version="1">MIYYKIPIKQQQTYYFFLYDLFKNKINNMNHAHSIIRPKIDKYFNKMTKINLKEKIKMKNDLNKGIRIGGWNTKTTPTDLDQIKLFLQTLKQDLINLTIITHSKKKNTYQEANYRPKNQTLFVDPQILDEIKQTKITLINDNFSSSNSKLLLSDLPPLKNQNTPPLKPIMISFKSIIKMNLKISAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-10-07" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ09</accession>
    <name>Q6YQ09_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sigma70_r2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_566"/>
    <dbReference type="EnsemblBacteria" id="BAD04651">
        <property type="protein sequence ID" value="BAD04651"/>
        <property type="gene ID" value="PAM_566"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_566"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2618550_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="78" mass="9079" checksum="15BEC38B8E7F55D0" modified="2004-07-05" version="1">MRNQLIDLHLSLVKKLVSKFKYYPCVLQKQDLYQEGVLGLIKALNNYVDLGYDFIAYATPTIKSEIRELIRRSLTSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ12</accession>
    <name>Q6YQ12_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">himA</name>
        <name evidence="2" type="ordered locus">PAM_563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_563"/>
    <dbReference type="EnsemblBacteria" id="BAD04648">
        <property type="protein sequence ID" value="BAD04648"/>
        <property type="gene ID" value="PAM_563"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_563"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_3_14"/>
    <dbReference type="OMA" id="HEIPKKQ"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-677-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="96" mass="10881" checksum="474AD7354B1BB4E3" modified="2004-07-05" version="1">MTKKELIKNIAEANKTSISKTEEFYNSFEHTLIESITSNEEVILSSKIGKFILKTRKAYTGRNPQTGQKLKISAKTVVSFKLSQTIKDKVKDLTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ17</accession>
    <name>Q6YQ17_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF2963 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">PAM_558</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_558"/>
    <dbReference type="EnsemblBacteria" id="BAD04643">
        <property type="protein sequence ID" value="BAD04643"/>
        <property type="gene ID" value="PAM_558"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_558"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065991_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-670-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="3">
        <location>
            <begin position="134"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="359" mass="41980" checksum="3D59516579145B85" modified="2004-07-05" version="1">MSSFRIGNKHYKIIPFLITTGTLLFFVFWIGGISYKYHLETEERRKLQEVDIKAKARELNNDLHNENKKLKKENEYMKDTPYEFQRDNGEKEYYNLFTNKLVKKIDKDDTIWEYDKNNGLLLKKTDRYNNVEEYGSHGKMIKKTLSDGVWMEYNPVNKKLIKRKNIDNSIEEFDDNEEKFKEIDKNGKVKFFKTKLYQNISDFKKLSANVFQLREVGFTAKELKDVGITDKELADSGYHLKDVVYTQKVLSDANLSLEPLEKVIYTLQQLKEAGYSEKYLKDVVYTQKGLSDANLSLEPLEKVIYTLKQLKDAGYKLKDLKDVGYSLQQAKEAGFSAKELRKVGFTAKELKDAGFNLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ20</accession>
    <name>Q6YQ20_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_555"/>
    <dbReference type="EnsemblBacteria" id="BAD04640">
        <property type="protein sequence ID" value="BAD04640"/>
        <property type="gene ID" value="PAM_555"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_555"/>
    <dbReference type="HOGENOM" id="CLU_2168401_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-667-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="110" mass="12884" checksum="78A859C35CB25635" modified="2004-07-05" version="1">MDKQQKLKKEFYEHCQCCGSDLGININAACLNLFGFIMGLISFISCGILLLYSSLIFLLRYFFTVIIFNEEFFLTIGLISFISLFLFCLISRFMPKLLFEKLDYEKVEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ34</accession>
    <name>Q6YQ34_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_541"/>
    <dbReference type="EnsemblBacteria" id="BAD04626">
        <property type="protein sequence ID" value="BAD04626"/>
        <property type="gene ID" value="PAM_541"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_541"/>
    <dbReference type="HOGENOM" id="CLU_1188980_0_0_14"/>
    <dbReference type="OMA" id="RENTLEC"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="SVM_signal" evidence="2">
        <location>
            <begin position="12"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="255" mass="30259" checksum="76EA1F62DDB69319" modified="2004-07-05" version="1">MLLSISKEIHIMFKLKTNLLFFKIVLFISLGFFLIISNNSVMAMENNELQNNSNFNDNNIEIPFENLPKQQTIQINNSFHEKNIIKFLFETKINLSKKLGVYDLKNLKEKYNGFLIKFNINVKQFVNTNNAKICLYSNASDLDNPIYDRYNFIGFLERIIIDNVSEEGLFNYKLKNNNHIEIYKSVFKQGLDNNLSESELEENVFKIILDFDIKKESNDLYMFFILYAYGFTESQNYEYINNFKLDKNITFYKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ38</accession>
    <name>Q6YQ38_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_537"/>
    <dbReference type="EnsemblBacteria" id="BAD04622">
        <property type="protein sequence ID" value="BAD04622"/>
        <property type="gene ID" value="PAM_537"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_537"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2012952_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="123" mass="14655" checksum="9DDB98438B05FFE3" modified="2004-07-05" version="1">MCEVWGAPQINSLTLETQKANLEHDLTQKQEELENNQKLSQQEKKELKKEINQQNDKIRSKENEIFTQDQKINQLETDLHQEKTIKTEKEKQINELIHQINEQNQNDRTTPKPTPRTKILNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ65</accession>
    <name>Q6YQ65_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04595">
        <property type="protein sequence ID" value="BAD04595"/>
        <property type="gene ID" value="PAM_510"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_510"/>
    <dbReference type="HOGENOM" id="CLU_2168401_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-611-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="110" mass="12945" checksum="05E4E22A1943490C" modified="2004-07-05" version="1">MDKQQKLKKEFYEHCQCCGSDLGININAACLNLFGFIMSFISFISCGILLLYSSLIFLLRYFFTVIIFNEEFFLTIGLISVISLFLFYLIARFMPKLLFEKLDYEKVEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ71</accession>
    <name>Q6YQ71_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_504</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_504"/>
    <dbReference type="EnsemblBacteria" id="BAD04589">
        <property type="protein sequence ID" value="BAD04589"/>
        <property type="gene ID" value="PAM_504"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_504"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145374_0_0_14"/>
    <dbReference type="OMA" id="CKSYMNS"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="151" mass="18254" checksum="8F7A7EC6F7846434" modified="2004-07-05" version="1">MFGFSRTCVSCPQKSFLALFPYDIIKEIELSSFPIVNFNFSNIFEWNIKQRVNGKNIKIPHNLTLLCKSYMNSQQFQNSNYFSLNLSGIQPKNHFLNKNFKKYFKLQKLKLKLKKDYEKKDTDIEILKKIECQYWYRYLENNYIQNFQISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ72</accession>
    <name>Q6YQ72_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_503</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_503"/>
    <dbReference type="EnsemblBacteria" id="BAD04588">
        <property type="protein sequence ID" value="BAD04588"/>
        <property type="gene ID" value="PAM_503"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_503"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2826910_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="66" mass="8127" checksum="C68BE6F34ED0C382" modified="2004-07-05" version="1">MFLERNKMLRQKLFKDFLKNKKNLAIRDQLIEMHLPLVKKIANQFKYFPKSLQREDLYQGFFVGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ75</accession>
    <name>Q6YQ75_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">PAM_500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_500"/>
    <dbReference type="EnsemblBacteria" id="BAD04585">
        <property type="protein sequence ID" value="BAD04585"/>
        <property type="gene ID" value="PAM_500"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_500"/>
    <dbReference type="eggNOG" id="COG0802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087829_5_2_14"/>
    <dbReference type="OMA" id="FVIVEYF"/>
    <dbReference type="OrthoDB" id="1827295at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-602-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="166" mass="19367" checksum="DE1D56E21F46D889" modified="2004-07-05" version="1">MKTKIYLETITNTPKETQILSYNLGKKLINQKKNTPKEKQSKTIILLQGSLGCGKTIFTKGFIKSFAILQNVCSPTFVISKTYKNKLHTIYHLDLYRTDLETEFLEELLEDLTYQDFVIVEYFQNCSYLFPDFAFLVEMTFLNETQRKITIYQNSNLDNKNKSGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="131" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQC5</accession>
    <name>Q6YQC5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Excinuclease ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">uvrA</name>
        <name evidence="15" type="ordered locus">PAM_450</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_450"/>
    <dbReference type="EnsemblBacteria" id="BAD04535">
        <property type="protein sequence ID" value="BAD04535"/>
        <property type="gene ID" value="PAM_450"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_450"/>
    <dbReference type="eggNOG" id="COG0178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001370_0_2_14"/>
    <dbReference type="OMA" id="PFEGIIP"/>
    <dbReference type="OrthoDB" id="152379at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-531-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="635"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="667"/>
            <end position="674"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="BAD04535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="972" mass="109749" checksum="6E0F772D45959E97" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQD0</accession>
    <name>Q6YQD0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04529">
        <property type="protein sequence ID" value="BAD04529"/>
        <property type="gene ID" value="PAM_444"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_444"/>
    <dbReference type="HOGENOM" id="CLU_1026138_0_0_14"/>
    <dbReference type="OMA" id="NSETHVY"/>
    <dbReference type="OrthoDB" id="1081137at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-524-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="271" mass="31837" checksum="D8345BAAD5D5039A" modified="2004-07-05" version="1">MNIKLFNQKYKLVSFLCVISSIILVLLLLILSLQKRHSTFRSSEKIQLTNNQTQKPNQQNFVKTPNLTKPKTQELQQEKETLPLYIQTVNDKTHYHFIVPDSEFMQDGTLKNSETHVYMENLKPTLMHKIIYKIQPQYDGWVACFPSFNGQDLAGAFLYSVMTGIKTPPLDLVGIYFESPFDKFDISDWNKYTLDDILQMKNESQNIYFFWRSPKMTNIYKKYHLFKPGKEKYHPTLNKPISPQNALMLTEEFIDKFIPNSPSKKSKETEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQD3</accession>
    <name>Q6YQD3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized NAD-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hcaD</name>
        <name evidence="4" type="ordered locus">PAM_441</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_441"/>
    <dbReference type="EnsemblBacteria" id="BAD04526">
        <property type="protein sequence ID" value="BAD04526"/>
        <property type="gene ID" value="PAM_441"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_441"/>
    <dbReference type="eggNOG" id="COG0446">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_1_0_14"/>
    <dbReference type="OMA" id="ACGIPYW"/>
    <dbReference type="OrthoDB" id="1149616at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-521-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="2">
        <location>
            <begin position="328"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="447" mass="49490" checksum="D88308A1E3E89986" modified="2004-07-05" version="1">MKVIVVGCTHAGTAAVKTIKKNNPQADVVVYERNDNISFLSCGIALYVGGVIKDSLGLFYSNPDELVSMDVCTKLKHEVLKLNFDKKEVLVQSLETGKQFKDNYDKLVIATGSWPVIPPIKGIDCKNVLMSKNFDHAKDIINYSKNVNKITIVGAGYIGIELAEAFAVQKKEVVLVDAEDRIMSKYLDKEFTDVAQKTLTDHGVTLALGQKIAGFETKDGLVTHVKTDKNTFETEMVIMCISFKPNTQLFAHHLETSFNGALVVNEYMQTSDPDVYACGDCVNVYYNPTQEVKYMPLATNAIRMGTLVGLNIEKPCVKYLGTQGTSGIKIIDLSISSTGLTENVAKALGKNYGTVTIKDANRPEFMPDYDAVMLKLVFDKETRKILGGQIVSRVDLTEKMNTLSVCMQNQMTVEQLAFVDFFFQPHFNKPWGLLNLAGLKALEVKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQD5</accession>
    <name>Q6YQD5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable cell division protein WhiA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">whiA</name>
        <name evidence="8" type="ordered locus">PAM_439</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in cell division and chromosome segregation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WhiA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_439"/>
    <dbReference type="EnsemblBacteria" id="BAD04524">
        <property type="protein sequence ID" value="BAD04524"/>
        <property type="gene ID" value="PAM_439"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_439"/>
    <dbReference type="eggNOG" id="COG1481">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053282_0_0_14"/>
    <dbReference type="OMA" id="FMDNTIS"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043937">
        <property type="term" value="P:regulation of sporulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01420">
        <property type="entry name" value="HTH_type_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018478">
        <property type="entry name" value="Sporu_reg_WhiA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003802">
        <property type="entry name" value="Sporulation_regulator_WhiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023054">
        <property type="entry name" value="Sporulation_regulator_WhiA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039518">
        <property type="entry name" value="WhiA_LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37307">
        <property type="entry name" value="PTHR37307"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02650">
        <property type="entry name" value="HTH_WhiA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14527">
        <property type="entry name" value="LAGLIDADG_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10298">
        <property type="entry name" value="WhiA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="SSF55608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00647">
        <property type="entry name" value="DNA_bind_WhiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WhiA_N" evidence="6">
        <location>
            <begin position="22"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="LAGLIDADG_WhiA" evidence="7">
        <location>
            <begin position="124"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_WhiA" evidence="5">
        <location>
            <begin position="222"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_WhiA" evidence="5">
        <location>
            <begin position="272"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="356" mass="42218" checksum="201DA4BD21480764" modified="2004-07-05" version="1">MPMSFNIKIKEEIACQKFLPIENFFELTALLHFGCELEKNHQKTLLWFQTKSIKIARRFLILIKTFYPNTNSFLMTSKEYNLPHLKSIHVGIEKDIPLILEKHHFFTQTPSDFLPLLKSQKAKKAFLRGIFLCIGFVNDPKKTNYHLEFFHKDRHKIELIKTLMLHFSLNAKKINHKKGFLVYLKESQMIIDFLRLIGALEIVFQYEKTIIQKDLNHIIKSSINFEISNEKKILTSANLQLQQINLIEKHFQIPNLKPKNTNLKMKNPKNEKSQKQLPNLEPKLLQIMLLRKENPDASLQELTQKYYHKHKQQITKSGLNYYFQKIKKLACEIETPQILAPSKEKNKYGKYRHRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQF7</accession>
    <name>Q6YQF7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_416"/>
    <dbReference type="EnsemblBacteria" id="BAD04501">
        <property type="protein sequence ID" value="BAD04501"/>
        <property type="gene ID" value="PAM_416"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_416"/>
    <dbReference type="HOGENOM" id="CLU_1843094_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="139" mass="16412" checksum="DB8B16B680DCAD07" modified="2004-07-05" version="1">MMDIQQTIINVVESKVFISFTSFIFGIFIYWLYFYIKELKSKYDFSDELRDIVNHYLKKGKISISEYGALVRLMAHMGNYLGIYRKHVETMIKEFGENGGLNFSEGIFDEKDNNQENKENNNNLDEILKENLKVKKSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQG1</accession>
    <name>Q6YQG1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04497">
        <property type="protein sequence ID" value="BAD04497"/>
        <property type="gene ID" value="PAM_412"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_412"/>
    <dbReference type="HOGENOM" id="CLU_2233760_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-497-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="105" mass="12270" checksum="9FC77C9D66649A22" modified="2004-07-05" version="1">MNTSDFFKKNLAIIIIFLFGIFIIVGFYHQRNNSKLNNETLSQLEPKSEESKPLKNKSDIKPFEIEKNVIKQIIEITSCLNITKEEKGFFNKELLPIMEKNDFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQH9</accession>
    <name>Q6YQH9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">himA</name>
        <name evidence="2" type="ordered locus">PAM_043</name>
        <name evidence="3" type="ordered locus">PAM_394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_043"/>
    <dbReference type="EnsemblBacteria" id="BAD04128">
        <property type="protein sequence ID" value="BAD04128"/>
        <property type="gene ID" value="PAM_043"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04479">
        <property type="protein sequence ID" value="BAD04479"/>
        <property type="gene ID" value="PAM_394"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_043"/>
    <dbReference type="KEGG" id="poy:PAM_394"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_3_14"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-473-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-59-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="96" mass="10962" checksum="53198D9B294AF051" modified="2004-07-05" version="1">MTKKELIKKIAEVNKTSISKTEEFYNSFENTLIKAIISNEEVSLSSKIGKFKLKSRKAYTGRNPKTRKKLKIPAKTVVTFKLSKTIKDQAKTLILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQJ3</accession>
    <name>Q6YQJ3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome segregation ATPase homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">smc</name>
        <name evidence="2" type="ordered locus">PAM_380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_380"/>
    <dbReference type="EnsemblBacteria" id="BAD04465">
        <property type="protein sequence ID" value="BAD04465"/>
        <property type="gene ID" value="PAM_380"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_380"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1141676_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="243" mass="28791" checksum="C3C3CF555AC5B441" modified="2004-07-05" version="1">MTEQLQNQLQEQKTLIETKNKELENNQKLSQQEKQELQKEINQQTDKIRSKENEIFTQDQKINQLETDLHQEKKINTEKEKQINELINQINEQNQMTEQLQNQLQEQKTLIETKNKELINNQALSEQEKQALQQEINQLTTNFQQKEKEYQATIYQKDQEITHLNQIINEQANEINRLSEELEQQIDKAQQGLHIEALEGTIKAQENTYSGAIKPLTTKITNDAVKITKRTTEKVTSWFKSWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQK0</accession>
    <name>Q6YQK0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YqaJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_333</name>
        <name evidence="3" type="ordered locus">PAM_373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04418">
        <property type="protein sequence ID" value="BAD04418"/>
        <property type="gene ID" value="PAM_333"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04458">
        <property type="protein sequence ID" value="BAD04458"/>
        <property type="gene ID" value="PAM_373"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_333"/>
    <dbReference type="KEGG" id="poy:PAM_373"/>
    <dbReference type="eggNOG" id="COG5377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1747782_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017482">
        <property type="entry name" value="Phage_endonuclease_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03033">
        <property type="entry name" value="phage_rel_nuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ" evidence="1">
        <location>
            <begin position="11"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="149" mass="17446" checksum="8F75F9ABADC28DFD" modified="2004-07-05" version="1">MEQLVHDKLFGTTFTANQYTLHGQKTEPIARQFFIQKTNLTFEDAIFTDDQVNFFSASLDGYNEKHQAVLEIKCPFVNENQEVSSTWTSFLTNPQLENIPQYYWAQVQCQLYCSQANFAYFLVYFNDQTKISCCSDLSRSNLYHENDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQM0</accession>
    <name>Q6YQM0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_353"/>
    <dbReference type="EnsemblBacteria" id="BAD04438">
        <property type="protein sequence ID" value="BAD04438"/>
        <property type="gene ID" value="PAM_353"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_353"/>
    <dbReference type="HOGENOM" id="CLU_1232954_0_0_14"/>
    <dbReference type="OMA" id="FIFIWEQ"/>
    <dbReference type="OrthoDB" id="2116149at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-421-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="224" mass="26670" checksum="9C643A517D4477F4" modified="2004-07-05" version="1">MRNLLMILKMIFSFNFLKYLISFDFKDFFYLLYSIFYSIFFTKSSFLFGFNVGWNINFINIYNIIKTIFVFIWEQLIILIYPLKLFSSLFDFLMQILKIFIDVFGSIIGYIKSSITNLTGQKLMDPSESMWEKIKEIAKLIFSVAVGGSVIYFLKEINNFLLNSFIKIGDLLFKIILRILDIISIVLKFFLFLFKKVIIILSFILSFFINFLYLWVFENAKKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQM6</accession>
    <name>Q6YQM6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_347"/>
    <dbReference type="EnsemblBacteria" id="BAD04432">
        <property type="protein sequence ID" value="BAD04432"/>
        <property type="gene ID" value="PAM_347"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_347"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1137139_0_0_14"/>
    <dbReference type="OrthoDB" id="1779749at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-414-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="241" mass="28688" checksum="B39576791F9542DE" modified="2004-07-05" version="1">MFNIIKKIIKWFFIILGLLLCLLIGFFFLTSDTDKLPKQQIPILKETAFENIEEWDDVNSEFKMIKAKYTFDGLNGIGYYQQQLANKENIGSFELMKIQERLETQKERSNLACYIKDRHPFDRWNNKGLTYKETSINGFKFSRFDKEDDSQLYLYVKLEKQFKENSSGNCLILKYQGPKHFLDDDKDYYLGRARVSDSNFELTNFHLHFNPVRKTLSIFKDKHNNDKVEEAEMNKNHPNGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQM7</accession>
    <name>Q6YQM7_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_346"/>
    <dbReference type="EnsemblBacteria" id="BAD04431">
        <property type="protein sequence ID" value="BAD04431"/>
        <property type="gene ID" value="PAM_346"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_346"/>
    <dbReference type="HOGENOM" id="CLU_989854_0_0_14"/>
    <dbReference type="OMA" id="CWRIKEP"/>
    <dbReference type="OrthoDB" id="2111090at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-413-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="168"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="281" mass="33757" checksum="0FE0FAAF8DEAA3DF" modified="2004-07-05" version="1">MLNLKNQFSRINLFFISLGLLFLVNHHPVMAIENKKICNLNMKIHNIWIQKKEDIVSHVINKNIDQIFSYLTLDYPCYNSSTNNKNDLCWRIKEPPNNLLFVFFDSGIRSNEDEFYSLEDLNEMGNGAKNMYIFWLTKTLYPQIKTQKDIINKEIFYQLKIKLKNIEIEKLNIELNLFKEIKLQLEKEIDNQTNIYLNTKKIILNLENYINNLEEINKKNQNINLENEKLKQQLNLKYIELQKEKEKFLNQQNNINKLQQELNQKTTTYMGIFNSLYKKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQN0</accession>
    <name>Q6YQN0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04428">
        <property type="protein sequence ID" value="BAD04428"/>
        <property type="gene ID" value="PAM_343"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_343"/>
    <dbReference type="eggNOG" id="ENOG5033PU3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239554_0_0_14"/>
    <dbReference type="OMA" id="NTKCIEI"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-408-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.91.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038365">
        <property type="entry name" value="EcoRII_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="201" mass="23965" checksum="1C75CED2CAC17B59" modified="2004-07-05" version="1">MLNNQDFFNIKHLNTNTKCIEILKTVFQKLTFNLPIDTYMKTNHQQLNHYFESNNINSQSQKVIRGKINEYLILLYFQNKGITNLYPQVNLFFIPDIKFDLVLFTKNKRIIAFNFKTCLRDRYKQTMVEGQQLKKLDTRFEFYLLTNNETETQRLNKKINQGKVQGINQVINLFSNSANNFLQNLITFQFIPFSNINIIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQN5</accession>
    <name>Q6YQN5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04423">
        <property type="protein sequence ID" value="BAD04423"/>
        <property type="gene ID" value="PAM_338"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_338"/>
    <dbReference type="HOGENOM" id="CLU_1979285_0_0_14"/>
    <dbReference type="OMA" id="LVIVNYY"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="124" mass="15166" checksum="30A2B6D7FCF12FF9" modified="2004-07-05" version="1">MTLLVIVNYYFQIYPPLKTKIPPLKTYHDIFQINYKNESKNIIKELIGKINLHKLENLQLYQIDPNKLDKYNKPIKTNYKQGLNIIYYRQEDLKYIQFFLTKTKQGYRVKKIHPMYKYISKQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQN8</accession>
    <name>Q6YQN8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SF4 helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_335"/>
    <dbReference type="EnsemblBacteria" id="BAD04420">
        <property type="protein sequence ID" value="BAD04420"/>
        <property type="gene ID" value="PAM_335"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_335"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2106489_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="115" mass="13353" checksum="1776DA49346F85AB" modified="2004-07-05" version="1">MIILSQFSRDTYSHYQGKSPEITALKGSGGIETNSDIVLMMSEFQPKLSKDQEKPLNIYNQNCNQLYLVSKNNESQKIIELSIKKNRSGTKKNLIYHFEMTTKHFKKSVIFYLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQR1</accession>
    <name>Q6YQR1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_312"/>
    <dbReference type="EnsemblBacteria" id="BAD04397">
        <property type="protein sequence ID" value="BAD04397"/>
        <property type="gene ID" value="PAM_312"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_312"/>
    <dbReference type="HOGENOM" id="CLU_1843094_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-372-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="156" mass="18420" checksum="3DB7CC4B599E60CB" modified="2004-07-05" version="1">MMDIQQTIINIVESKVFISFTSFIFGIFIYWLYFYIKELKSKYDFSDELRDIVNHYLKKGKISISEYGALVRLMAHMGNYLGIYRKHVETMIKEFGEHGGLNFSEGIFDEKDNNQENKENNNLDEILKENLKLKNQLNNIKNPLIVESIDDTENDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQS0</accession>
    <name>Q6YQS0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">smtA</name>
        <name evidence="4" type="ordered locus">PAM_303</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_303"/>
    <dbReference type="EnsemblBacteria" id="BAD04388">
        <property type="protein sequence ID" value="BAD04388"/>
        <property type="gene ID" value="PAM_303"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_303"/>
    <dbReference type="eggNOG" id="COG4122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067676_4_0_14"/>
    <dbReference type="OMA" id="YHINVIW"/>
    <dbReference type="OrthoDB" id="1948290at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-361-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="194" mass="22391" checksum="EE26D1EFA522E4A1" modified="2004-07-05" version="1">MFDFNKEKNLQKLKKYAQENKIPIIQDQGLALLLDVISQNKITNILEIGTAIGYSALAMSSLSTKIDTLERDFINYNLAKNFLKETPYHINVIWQEALIYPTCNLKKYDLIFIDAAKAQYQKLFCKYAPLLKKQGIIVFDNLNLSCFKKAKTTKNNQGIFKKMHNFQTFLTNHPDFCTTFQDVGDGLIISYLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="118" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQS1</accession>
    <name>Q6YQS1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">greA</name>
        <name evidence="11" type="ordered locus">PAM_302</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_302"/>
    <dbReference type="EnsemblBacteria" id="BAD04387">
        <property type="protein sequence ID" value="BAD04387"/>
        <property type="gene ID" value="PAM_302"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_302"/>
    <dbReference type="eggNOG" id="COG0782">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101379_2_0_14"/>
    <dbReference type="OMA" id="TWLTQEA"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="22"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="97"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAD04387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="170" mass="19449" checksum="5C529FBBEB02920D" modified="2004-07-05" version="1">MKNHQKIKKEGLLFMNNKIYELTQSGIEKLKKELTFLKEVKRKENLEALKEAREQGDLSENADYDAARNEQALIEHRISEIQNILKNVRVVKVSKEREVSIGKKVSLELLHTKQQQEIELVSTLEADPFNNKISIESPLGQNIKGHQIGDVVFVTGETGNTFRVKIVDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQS7</accession>
    <name>Q6YQS7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_296"/>
    <dbReference type="EnsemblBacteria" id="BAD04381">
        <property type="protein sequence ID" value="BAD04381"/>
        <property type="gene ID" value="PAM_296"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_296"/>
    <dbReference type="eggNOG" id="COG1764">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1813852_0_0_14"/>
    <dbReference type="OMA" id="ICFYKTS"/>
    <dbReference type="OrthoDB" id="1984062at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-354-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="142" mass="16265" checksum="C05D367F6D9A9150" modified="2004-07-05" version="1">MIIFKTTAYFNPHLDDLCFFEEKEGITKKLVSALEPSNKQSGPVDLFCLSWAICFYKTSKKILAEQDYTNKDLKVKVTLEMQKDDKGFYFKPTAILGIQDMTLEQTEIIADATHKRCPISRLISADENVSVKVLNYNELITE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-04-26" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQT0</accession>
    <name>TYSY_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thymidylate synthase</fullName>
            <shortName evidence="1">TS</shortName>
            <shortName evidence="1">TSase</shortName>
            <ecNumber evidence="1">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">thyA</name>
        <name type="ordered locus">PAM_293</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQT0"/>
    <dbReference type="SMR" id="Q6YQT0"/>
    <dbReference type="STRING" id="262768.PAM_293"/>
    <dbReference type="EnsemblBacteria" id="BAD04378">
        <property type="protein sequence ID" value="BAD04378"/>
        <property type="gene ID" value="PAM_293"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_293"/>
    <dbReference type="eggNOG" id="COG0207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021669_0_0_14"/>
    <dbReference type="OMA" id="KQYLDLC"/>
    <dbReference type="OrthoDB" id="1212177at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-351-MON"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000140998" description="Thymidylate synthase">
        <location>
            <begin position="1"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <begin position="190"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <begin position="231"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00008"/>
        </source>
    </evidence>
    <sequence length="288" mass="33649" checksum="449B4530A2920AC4" modified="2004-07-05" version="1">MNTYLDLCRFILQKGSFRNDRTNTGTKSVFGYQMRFNLEEGFPLLTTKKMNLRSIIHELLWFLKGDTNICYLVQNNVNIWNEWPYQKYQQSAFFQNETLKEFLEKIKNDPLFAIKHGNLGPVYGKQWRDFNGVDQIKFLISEIKTNPNSRRLILNSWNPPLLNQMALPPCHVLIQFYVHQGKLSLQLYQRSGDVFLGIPFNIASYSLLLMMVAQVTNLQPYEFIHTLGDAHIYSNHLAQVQTQIQRTPKKLPQMILNPDIKNIDDFKFSDFTLQNYQCDGILKGDIAV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-29" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQU0</accession>
    <name>G6PI_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="1">GPI</shortName>
            <ecNumber evidence="1">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phosphoglucose isomerase</fullName>
            <shortName evidence="1">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Phosphohexose isomerase</fullName>
            <shortName evidence="1">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pgi</name>
        <name type="ordered locus">PAM_283</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPI family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQU0"/>
    <dbReference type="SMR" id="Q6YQU0"/>
    <dbReference type="STRING" id="262768.PAM_283"/>
    <dbReference type="EnsemblBacteria" id="BAD04368">
        <property type="protein sequence ID" value="BAD04368"/>
        <property type="gene ID" value="PAM_283"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_283"/>
    <dbReference type="eggNOG" id="COG0166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037303_0_1_14"/>
    <dbReference type="OMA" id="CPAYAYG"/>
    <dbReference type="OrthoDB" id="417261at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-341-MON"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0312">Gluconeogenesis</keyword>
    <keyword id="KW-0324">Glycolysis</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000180698" description="Glucose-6-phosphate isomerase">
        <location>
            <begin position="1"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <sequence length="426" mass="48481" checksum="0EEFCA851209A4AF" modified="2004-07-05" version="1">MLKLNLEGIYNFLDWHNYAQTFAPQIKVIHQKLHQDQQLKEKYLGWLELPLHFDFQELEKMKQLKNSHPNLDVLVVIGIGGSYLGAKAGIEFLQTPFKKTKPEILFAGHQASGNYLTNLLHYLKDKNWAINVISKSGITLEPALAFRILKKEIEEKYGKQLAKNRIFVTTDSQKGVLLNLALKEGYQTFVIPDSVGGRFSVFTSVGILPFVFANLDVVSMMKGALQAYHDTFQEDLFQNQAYQYALARYLLHTQQNKKMELLVSYEPHLLSFSEWWKQLFAESEGKEEKGLFVGATNNSTDLHSLGQFIQEGTKMLFETVLNVTSIKDDCVVPHIPNELDNLNYVAGKTYSQINQKILQATKQAHIEGKVPNLEIVIPTLDAYHFGYLAYFFQKACAMSGSLLGINPFNQPGVEIYKQKMFALLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQU1</accession>
    <name>Q6YQU1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_282"/>
    <dbReference type="EnsemblBacteria" id="BAD04367">
        <property type="protein sequence ID" value="BAD04367"/>
        <property type="gene ID" value="PAM_282"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_282"/>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_551894_0_0_14"/>
    <dbReference type="OMA" id="LRITILW"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="494" mass="55928" checksum="9210A54CCF0DEAB7" modified="2004-07-05" version="1">MPHPSKPANQTPKSFKRPIWINLIILTFPIAIYLLFQQLSVSIDFYIIGNQPNSSTNLDKTISYMAQIKKILQSVAIALGGAGVILVAREYKKKNFTKAKQYATLAFLLAIISSLFFLVVLGLGVLLPAPFGDIFLNKSYHSQNGLTYYYLILITFVAITMNAVFIGLERAKEKTRFVLILNICLIITRISISFAFKAIKQNQVNLIDLALADLIANLLLTLVTFYCMFSSKNIFKLQFKNLVFSKRTVKTILKLAVTLIIAKSTYEIGKLIILAMIDSYFTKDQENLVDIFGFVMAVNGIFYAISNSFEDSQSAMVSQSVTFQSNSKTFKIFKNVVVITLIIGIIGVFINQFCGEQLLRALKPEKVFTTQKITSFKEILNWEQTSLFFSVWTTLMMGYVASYKKNANLIFVINLLRVVLRITILWFLHDILPQLKDVSIPDATQCGLSTFGSNIIVFLTTTYLFVSFLRQNKTNQTPRFKKNKNNALQTKIIK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-08-16" modified="2022-08-03" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQU7</accession>
    <name>EFP_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor P</fullName>
            <shortName evidence="1">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">efp</name>
        <name type="ordered locus">PAM_276</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the elongation factor P family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQU7"/>
    <dbReference type="SMR" id="Q6YQU7"/>
    <dbReference type="STRING" id="262768.PAM_276"/>
    <dbReference type="EnsemblBacteria" id="BAD04361">
        <property type="protein sequence ID" value="BAD04361"/>
        <property type="gene ID" value="PAM_276"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_276"/>
    <dbReference type="eggNOG" id="COG0231">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074944_0_1_14"/>
    <dbReference type="OMA" id="WSVVEFQ"/>
    <dbReference type="OrthoDB" id="1260763at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-334-MON"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00038">
        <property type="entry name" value="efp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0251">Elongation factor</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000094299" description="Elongation factor P">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <sequence length="189" mass="21591" checksum="208890D053AF8FBD" modified="2004-07-05" version="1">MINTNDFKTGQTIKFNNQIYQILEFLHVKPGKGAAFVRTKLRNLRTGSVIDYTFNAGIKVQPALITKIKMQFLYALEDNYIFMNTQNYEQLEINKHQLKDFLKYLYEGLLVDIIFYENDEIVGITLPDKISIKVAYTEPGAKGDTKTNSLKDAALETGLVIKVPLFINIGEKIIINTETGLYLSRDNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQV4</accession>
    <name>Q6YQV4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_269</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_269"/>
    <dbReference type="EnsemblBacteria" id="BAD04354">
        <property type="protein sequence ID" value="BAD04354"/>
        <property type="gene ID" value="PAM_269"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_269"/>
    <dbReference type="HOGENOM" id="CLU_1197808_0_0_14"/>
    <dbReference type="OMA" id="RQFAVWT"/>
    <dbReference type="OrthoDB" id="1194950at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-326-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="231" mass="27539" checksum="2DF4B8F3DF4543C3" modified="2004-07-05" version="1">MNFSFFQKEKEFKLLTNIYNSLQGEPFLTQETTLKGKETKVEFYYLDQSKYYSTLFQSRQFAVWTADKGVCRLLVEKKYYEEFGAFYQKDINDMWLDFIWQIFQKEATLIKTIKFLFVAVLVPILLNAFLLSGQISVWLRIPAFVVLISSSFSMNYWMKNQQKKLHIFRDKKLQETLDKIQETLGIELYESLKEKQKQFNPTFVEPKSDQNPNEDTPKNKDNTIDEINELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQV7</accession>
    <name>Q6YQV7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04351">
        <property type="protein sequence ID" value="BAD04351"/>
        <property type="gene ID" value="PAM_266"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_266"/>
    <dbReference type="eggNOG" id="COG4760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1244278_0_0_14"/>
    <dbReference type="OMA" id="IWTIENI"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010539">
        <property type="entry name" value="UCP009160"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41282">
        <property type="entry name" value="PTHR41282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12811">
        <property type="entry name" value="BaxI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="222" mass="25557" checksum="5DD19E09F5BACFE3" modified="2004-07-05" version="1">MLLCVTAITSMFFYPILKPAILKNLNIHAIYFSMIALGFLNYGIYSAGLKQVEISKACGLIYSFIEGIILSIIFVVLNLVYANLVEIAFMAIFATFIVFVVMSHAYYKGFIKVTNRFRQIMLYCSFALVVSYIVRLVLSLCSIWTIENIIYNSFLTLPISLIMLGFVSMFLALHFDYTEQMIKQGMPKKYEWQVSLAFATTLIEIFLRIMLILLRLFGQERK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-29" modified="2022-08-03" version="113" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQV9</accession>
    <name>EFG_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor G</fullName>
            <shortName evidence="1">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fusA</name>
        <name type="ordered locus">PAM_264</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQV9"/>
    <dbReference type="SMR" id="Q6YQV9"/>
    <dbReference type="STRING" id="262768.PAM_264"/>
    <dbReference type="EnsemblBacteria" id="BAD04349">
        <property type="protein sequence ID" value="BAD04349"/>
        <property type="gene ID" value="PAM_264"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_264"/>
    <dbReference type="eggNOG" id="COG0480">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002794_4_1_14"/>
    <dbReference type="OMA" id="AATTCHW"/>
    <dbReference type="OrthoDB" id="88967at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-321-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0251">Elongation factor</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000091172" description="Elongation factor G">
        <location>
            <begin position="1"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="tr-type G">
        <location>
            <begin position="8"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="17"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <sequence length="688" mass="76258" checksum="9360AA2E94F66E54" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-29" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQW0</accession>
    <name>RS7_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsG</name>
        <name type="ordered locus">PAM_263</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQW0"/>
    <dbReference type="SMR" id="Q6YQW0"/>
    <dbReference type="STRING" id="262768.PAM_263"/>
    <dbReference type="EnsemblBacteria" id="BAD04348">
        <property type="protein sequence ID" value="BAD04348"/>
        <property type="gene ID" value="PAM_263"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_263"/>
    <dbReference type="eggNOG" id="COG0049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072226_1_1_14"/>
    <dbReference type="OMA" id="NVMPHVE"/>
    <dbReference type="OrthoDB" id="1540940at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-320-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_0000124312" description="30S ribosomal protein S7">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <sequence length="156" mass="18231" checksum="86487D727B216FFA" modified="2004-07-05" version="1">MSRKGHIKKRDVQPDPVYNSKLVTKIINIIMEDGKKGKAQTIFYQALKQVKTITNREPIKVFHEALNNIMPVLEVRTRRMGGQNYQVPSEVRPERRQSLGLRWIVKYTKESNEKTMEERLAKEIVDASLGNGVLVKKREETHRMAEANKAFAHYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQW9</accession>
    <name>Q6YQW9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Preprotein translocase subunit SecE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">secE</name>
        <name evidence="8" type="ordered locus">PAM_254</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_254"/>
    <dbReference type="EnsemblBacteria" id="BAD04339">
        <property type="protein sequence ID" value="BAD04339"/>
        <property type="gene ID" value="PAM_254"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_254"/>
    <dbReference type="eggNOG" id="COG0690">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125831_0_0_14"/>
    <dbReference type="OMA" id="EYSWLNI"/>
    <dbReference type="OrthoDB" id="2133117at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-311-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="136" mass="15733" checksum="F82FB69FC0CA0B57" modified="2004-07-05" version="1">MGIKIVSENKPNQLLEVIKREYSWLNILLITTSILSLALCGQLWQQKQFETMHWALPCALVLLSVFIFAIGSFAFFKDAFLQIFNISWPSLKQILFKTLQVIFFTLFLILFVHAIDSYVIGKLTQFCVKIKNLLSK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-01" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQX5</accession>
    <name>RNPA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribonuclease P protein component</fullName>
            <shortName evidence="1">RNase P protein</shortName>
            <shortName evidence="1">RNaseP protein</shortName>
            <ecNumber evidence="1">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Protein C5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rnpA</name>
        <name type="ordered locus">PAM_248</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RnpA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQX5"/>
    <dbReference type="SMR" id="Q6YQX5"/>
    <dbReference type="STRING" id="262768.PAM_248"/>
    <dbReference type="EnsemblBacteria" id="BAD04333">
        <property type="protein sequence ID" value="BAD04333"/>
        <property type="gene ID" value="PAM_248"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_248"/>
    <dbReference type="eggNOG" id="COG0594">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117179_9_1_14"/>
    <dbReference type="OMA" id="FVIVIKA"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00227">
        <property type="entry name" value="RNase_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020539">
        <property type="entry name" value="RNase_P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00648">
        <property type="entry name" value="RIBONUCLEASE_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000198502" description="Ribonuclease P protein component">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00227"/>
        </source>
    </evidence>
    <sequence length="141" mass="16867" checksum="03FBC3D423FF3101" modified="2004-07-05" version="1">MWNLYFLKLLIDVLNIKVKNFRIIKKMKRKYILKKESEITPVFKSKKRYGNSLFIIYYVKQTAFPHFKFALSVGKKYGKAHERNLIKRRLRAIIRSVSPCLNPKMFFVIVIKAQAKNLTFQQLKTFFLQFATKTRILLSNK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-08-02" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQX6</accession>
    <name>RL34_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmH</name>
        <name type="ordered locus">PAM_247</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQX6"/>
    <dbReference type="SMR" id="Q6YQX6"/>
    <dbReference type="STRING" id="262768.PAM_247"/>
    <dbReference type="EnsemblBacteria" id="BAD04332">
        <property type="protein sequence ID" value="BAD04332"/>
        <property type="gene ID" value="PAM_247"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_247"/>
    <dbReference type="eggNOG" id="COG0230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129938_2_0_14"/>
    <dbReference type="OrthoDB" id="2069770at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-298-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020939">
        <property type="entry name" value="Ribosomal_L34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="PTHR14503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00784">
        <property type="entry name" value="RIBOSOMAL_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000187431" description="50S ribosomal protein L34">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <sequence length="44" mass="5129" checksum="59E70393FAAB8205" modified="2004-07-05" version="1">MKRTYQPSKIKRKRTHGFRARMATVGGCKVLARRRSKGRLQLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQY0</accession>
    <name>Q6YQY0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_243"/>
    <dbReference type="EnsemblBacteria" id="BAD04328">
        <property type="protein sequence ID" value="BAD04328"/>
        <property type="gene ID" value="PAM_243"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_243"/>
    <dbReference type="eggNOG" id="COG3963">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_939539_0_0_14"/>
    <dbReference type="OMA" id="FPYVFFS"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-292-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="296" mass="35915" checksum="ACEB5534539F55A0" modified="2004-07-05" version="1">MLSICTLMLVFFHDFKECVNKGQIYWQYKYKAPTFMPEIDFDTTGKEDNILDYEEGYYPGHHTFIKTVWYFTHQSNLFVLIVYALFFTKVRQKNWYHYVVFACLVSILMTALIFHTLIDKGRHFYEPKFSLSFFLSHLHHTLAPLCYLYFYFKVNSYAIPYKKMWIAFIHPLLYMTFFSLFGFLSMQDYFQDLQKDKPIITSEKQAAKRDPFKMFPYVFFSPFKQKLNNPANAQNLEDKENRHHKRYRFVYSCYDFVCLVFSCLFVFTVSMTYTLLWIKKRLINKKTTPHYKKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQY8</accession>
    <name>Q6YQY8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M41 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_235"/>
    <dbReference type="EnsemblBacteria" id="BAD04320">
        <property type="protein sequence ID" value="BAD04320"/>
        <property type="gene ID" value="PAM_235"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_235"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_862877_0_0_14"/>
    <dbReference type="OrthoDB" id="2173925at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-282-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M41" evidence="2">
        <location>
            <begin position="27"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="322" mass="37139" checksum="7618E6FBBD8B281A" modified="2004-07-05" version="1">MQKISSETIIQAKENVLLGITNSSKTYNHKEKEIVSTHAAAKIIISQVKNTHFLSSVSLIPRSYDKILTLFAKEQTPNILLKETLIQEITVLLAGKAAEEVICETTIDKACSDFVEAFHKSQELTRFFGYNSISVKDKEDLQRDILKKCFSDAKALVKLNEPLIKELSQKLQEQNITPMPQIKEFLQNKQIKDMKEIKIQPFQPAKGFNKTTIWHFICTLLFVLFLLLSTILIFKTIYWLFAIPKNYFIFKKKIITTFLIVVSLMFSILFFSFDCYHHLPFINATSNITVSDLLNKIDNYETKKILILLKIVGWKVFITISN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-04-04" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQZ7</accession>
    <name>RS13_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsM</name>
        <name type="ordered locus">PAM_225</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQZ7"/>
    <dbReference type="SMR" id="Q6YQZ7"/>
    <dbReference type="STRING" id="262768.PAM_225"/>
    <dbReference type="EnsemblBacteria" id="BAD04310">
        <property type="protein sequence ID" value="BAD04310"/>
        <property type="gene ID" value="PAM_225"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_225"/>
    <dbReference type="eggNOG" id="COG0099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103849_1_1_14"/>
    <dbReference type="OMA" id="YRGLRHK"/>
    <dbReference type="OrthoDB" id="1772647at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-271-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_0000230536" description="30S ribosomal protein S13">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="121" mass="13696" checksum="8677E3CD3A5FD83B" modified="2004-07-05" version="1">MARIAGIDIPSDKRVVIALTYIYGLGNKLSHKILNELNIDQNIRVKNLTEQQLSALRSEITKYNVEGDLRREVTLNIKRLMEIGAYRGLRHRKGLPVRGQKTRNNAHTVKGKPKAIAGKKK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQZ8</accession>
    <name>RL36_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmJ</name>
        <name type="ordered locus">PAM_224</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQZ8"/>
    <dbReference type="SMR" id="Q6YQZ8"/>
    <dbReference type="STRING" id="262768.PAM_224"/>
    <dbReference type="EnsemblBacteria" id="BAD04309">
        <property type="protein sequence ID" value="BAD04309"/>
        <property type="gene ID" value="PAM_224"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_224"/>
    <dbReference type="eggNOG" id="COG0257">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135723_3_3_14"/>
    <dbReference type="OrthoDB" id="2066169at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-270-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_L36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_L36_sp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="SSF57840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000126229" description="50S ribosomal protein L36">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <sequence length="38" mass="4634" checksum="67A2EA8BC04EFBF3" modified="2004-07-05" version="1">MKVRASVKKRSEDDIIVRRKGRIYVINKKNRRHNQRQG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-11-28" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR07</accession>
    <name>RL6_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplF</name>
        <name type="ordered locus">PAM_215</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR07"/>
    <dbReference type="SMR" id="Q6YR07"/>
    <dbReference type="STRING" id="262768.PAM_215"/>
    <dbReference type="EnsemblBacteria" id="BAD04300">
        <property type="protein sequence ID" value="BAD04300"/>
        <property type="gene ID" value="PAM_215"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_215"/>
    <dbReference type="eggNOG" id="COG0097">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065464_1_2_14"/>
    <dbReference type="OMA" id="KPDPYKG"/>
    <dbReference type="OrthoDB" id="1398618at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-261-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002358">
        <property type="entry name" value="Ribosomal_L6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00525">
        <property type="entry name" value="RIBOSOMAL_L6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000260909" description="50S ribosomal protein L6">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <sequence length="184" mass="20640" checksum="A1A6E28ADFD66F97" modified="2004-07-05" version="1">MSRVGNKAIEVPNAVKVDIKDRNFISVEGPKGKLEYQFNHRLTITNENKVITVKRPNDEIFMKKIHGTTRALLSNMVEGVSKGFQKTLKIVGLAYRAQIKDKQLILSLGFSHPVSVAIPDNLEVVVNQNTEIVIKGIDKQLVGEFAAKNVKLRKPEPYKGKGIRYVGQYVRQKAGKSAKKTRKD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-06-07" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR08</accession>
    <name>RS8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsH</name>
        <name type="ordered locus">PAM_214</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR08"/>
    <dbReference type="SMR" id="Q6YR08"/>
    <dbReference type="STRING" id="262768.PAM_214"/>
    <dbReference type="EnsemblBacteria" id="BAD04299">
        <property type="protein sequence ID" value="BAD04299"/>
        <property type="gene ID" value="PAM_214"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_214"/>
    <dbReference type="eggNOG" id="COG0096">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098428_0_2_14"/>
    <dbReference type="OMA" id="FDQGYIL"/>
    <dbReference type="OrthoDB" id="1692188at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-260-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000126456" description="30S ribosomal protein S8">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <sequence length="130" mass="14359" checksum="3A61D0E4310BC87F" modified="2004-07-05" version="1">MVMTDPIADMLTRIRNANQMSHLKVLVPASKLKLEILAVLKKEGFIKDFYLPQSSREIIISLKYAPNKERVIKGLKRVSKPGLRVYASAEQIPKVLNGLGVALVSTSKGILTDAQARLSQVGGEVLAYIW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-07-19" modified="2022-05-25" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR10</accession>
    <name>RL5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplE</name>
        <name type="ordered locus">PAM_212</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR10"/>
    <dbReference type="SMR" id="Q6YR10"/>
    <dbReference type="STRING" id="262768.PAM_212"/>
    <dbReference type="EnsemblBacteria" id="BAD04297">
        <property type="protein sequence ID" value="BAD04297"/>
        <property type="gene ID" value="PAM_212"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_212"/>
    <dbReference type="eggNOG" id="COG0094">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061015_2_1_14"/>
    <dbReference type="OMA" id="ERMYAFL"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_0000124961" description="50S ribosomal protein L5">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <sequence length="181" mass="20318" checksum="C8AA503486D32A4F" modified="2004-07-05" version="1">MSMKKENTLDYSKITATLMETFNYKSVMQVPKVEKVVINMGVGDAIFNVKVLDDVVEELKLLSGQSPVITKAKKAISNFKLREGMPIGAKVTLRGARKEAFLCKLTRLVFPRVRDFRGISGKSFDGRGNYALGLKEQIVFPEINIDKVKKIRGMDIIIVTTAKNNTQAKKLLELYGMPFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR23</accession>
    <name>Q6YR23_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_195"/>
    <dbReference type="EnsemblBacteria" id="BAD04280">
        <property type="protein sequence ID" value="BAD04280"/>
        <property type="gene ID" value="PAM_195"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_195"/>
    <dbReference type="HOGENOM" id="CLU_1650407_0_0_14"/>
    <dbReference type="OrthoDB" id="2117462at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-239-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="160" mass="19303" checksum="9CD576BEBCB11C74" modified="2004-07-05" version="1">MLIIINILILLLNINSYFIKAHSTFKLNYQIKSTFKIKVKKETLNNTIHNIKVKNTNKALIFIHKNIYPNYYKKVSFHKTINQNKGELMSKSILNCPQNIIFIYHDGKMPFIKDKTHTLEAIINMKNKYNNLYIFYYEPTLIQKYLYPKKTTWYKPYRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR29</accession>
    <name>Q6YR29_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type dipeptide/oligopeptide system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dppC</name>
        <name evidence="6" type="ordered locus">PAM_189</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_189"/>
    <dbReference type="EnsemblBacteria" id="BAD04274">
        <property type="protein sequence ID" value="BAD04274"/>
        <property type="gene ID" value="PAM_189"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_189"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_5_4_14"/>
    <dbReference type="OMA" id="TDWFLVM"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="85"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="267" mass="30548" checksum="1B8FFD6EA2A6C4B0" modified="2004-07-05" version="1">MKKNFKPFLFFQKKLKYWAKNKNILFGSLFLTILFLAVYLIPFTPLYKNPDASSHYKRLQSISLKHLMGTDSTGHDLFNRMLEGTKKSLTIGFCSIMMASIIGTLLGIISGYFKNIFDNIINFICDILVVFPDVILAILIMFFLKDNKKLSLIIALSISNAPTFIRIIRANTMKIRQKGFIKASKALGSNEFCIIFKHVLPHLWSIIITRITIGMATVILTISGLSFVGLGLDPTIPEWGNILNASRSDIRFYPHLIFWTFYHYFIN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-09-22" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR36</accession>
    <name>RSGA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="1">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsgA</name>
        <name type="synonym">pam182</name>
        <name type="ordered locus">PAM_182</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR36"/>
    <dbReference type="SMR" id="Q6YR36"/>
    <dbReference type="STRING" id="262768.PAM_182"/>
    <dbReference type="EnsemblBacteria" id="BAD04267">
        <property type="protein sequence ID" value="BAD04267"/>
        <property type="gene ID" value="PAM_182"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_182"/>
    <dbReference type="eggNOG" id="COG1162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033617_2_1_14"/>
    <dbReference type="OMA" id="CLVAAYD"/>
    <dbReference type="OrthoDB" id="908180at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-223-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000216045" description="Small ribosomal subunit biogenesis GTPase RsgA">
        <location>
            <begin position="1"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="CP-type G" evidence="2">
        <location>
            <begin position="77"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="179"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01058"/>
        </source>
    </evidence>
    <sequence length="306" mass="35157" checksum="630DED6328D41D8D" modified="2004-07-05" version="1">MEKALVLRFLAGVYYIKDLETQIILEAKKRGKLKTPDIKTTQKENSSASDFIIKVGDIVFYELSCDTYLIQSILPRKNELKRPNVANIDQVLLVFSLVKPNFQFLLLDKFLLILEQQKLDVVLVFSKIDLLEPENLTTMQQQLSYYQKFQPFYYINSKQKIGIDALKHIFANQITVLAGQTGVGKSTLLKALIPDAKLKTQEISESLGRGKHTTKNAQLYEFNGGFIVDTPGFSKLDLTTFCPRTLKNFYPDFVEHVCDCFFGESCLHLQEEKCGVKKSLENGKILPSRYQNYVSFYEEIKNQLKY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-12-21" modified="2022-08-03" version="113" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR39</accession>
    <name>ECFA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Energy-coupling factor transporter ATP-binding protein EcfA</fullName>
            <shortName evidence="1">ECF transporter A component EcfA</shortName>
            <ecNumber evidence="1">3.6.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ecfA</name>
        <name type="synonym">cbiO</name>
        <name type="ordered locus">PAM_179</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR39"/>
    <dbReference type="SMR" id="Q6YR39"/>
    <dbReference type="STRING" id="262768.PAM_179"/>
    <dbReference type="EnsemblBacteria" id="BAD04264">
        <property type="protein sequence ID" value="BAD04264"/>
        <property type="gene ID" value="PAM_179"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_179"/>
    <dbReference type="eggNOG" id="COG1122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_14"/>
    <dbReference type="OMA" id="EVFCLIG"/>
    <dbReference type="OrthoDB" id="1713578at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-219-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51246">
        <property type="entry name" value="CBIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000092053" description="Energy-coupling factor transporter ATP-binding protein EcfA">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01710"/>
        </source>
    </evidence>
    <sequence length="271" mass="30800" checksum="8872C13B6B218841" modified="2004-07-05" version="1">MISIQNLTFYYGCNPILKDLNLTIQNNSWVSIVGHNGSGKSTLAKILVGLLSCTKGQILIDNIVLNEKNLPLLRPKIGMVFQNPDYQFTGLTVREDIAFGLENHNVCREEIIAKVWQYAKMVKIDDLLDTNVNQLSGGQKQRVAIASILAMEPEIIIFDEVTSFLDPQGALEVQKIIQTIKNKILITITHDLEFAAKSDEIIVLDQGKLITQTPPQNLFQDPLFLQQYKLNPPLSLELYYEILKDSTTKNIKNNQMLENLKDILWQYNLKK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-01-15" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR48</accession>
    <name>TPIS_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Triosephosphate isomerase</fullName>
            <shortName evidence="1">TIM</shortName>
            <shortName evidence="1">TPI</shortName>
            <ecNumber evidence="1">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tpiA</name>
        <name type="ordered locus">PAM_170</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR48"/>
    <dbReference type="SMR" id="Q6YR48"/>
    <dbReference type="STRING" id="262768.PAM_170"/>
    <dbReference type="PRIDE" id="Q6YR48"/>
    <dbReference type="EnsemblBacteria" id="BAD04255">
        <property type="protein sequence ID" value="BAD04255"/>
        <property type="gene ID" value="PAM_170"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_170"/>
    <dbReference type="eggNOG" id="COG0149">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024251_2_3_14"/>
    <dbReference type="OMA" id="QEVCGAI"/>
    <dbReference type="OrthoDB" id="1266295at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-209-MON"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0312">Gluconeogenesis</keyword>
    <keyword id="KW-0324">Glycolysis</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000009849" description="Triosephosphate isomerase">
        <location>
            <begin position="1"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="1">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="13"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <sequence length="274" mass="30179" checksum="89AD6A93D9A86EF4" modified="2004-07-05" version="1">MNYKPRTKVIAGNWKMYKCKDEALEFIQKVSLQVPDQTQVQTLIFPQLTLLDSLAQLQGTNLQVGAQNMFYESEGAFTGEVSPQNLLSLGVKHVLLGHSERRTFFGETDQTVNLKLLSALKHKLVPTVCVGESLLTKENNQTQVFLDQQLTNIFAGVPEEALQNIIIAYEPVWAIGTGKSATPQDANKVIEQIRDKVTALYSSQASCAMRIIYGGSVSVANIKTILEQPAIDGILAGKASLQTEDFLFFAQIASKQALASTKDIFQKNDCPFCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR58</accession>
    <name>Q6YR58_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hemolysin III homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">PAM_158</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_158"/>
    <dbReference type="EnsemblBacteria" id="BAD04243">
        <property type="protein sequence ID" value="BAD04243"/>
        <property type="gene ID" value="PAM_158"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_158"/>
    <dbReference type="eggNOG" id="COG1272">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051078_1_0_14"/>
    <dbReference type="OMA" id="HEVFHSL"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="PTHR20855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="231" mass="26462" checksum="FC1FBB4899002DF0" modified="2004-07-05" version="1">MIVKWATKPSDKQTLGEEIANAISHGLMIPLGVFILVCFCLKASVMSNPNGYIVLVFSISMIILYLMSTLYHSLSFTKAHNFFQKTDHISIYLLIWGTFAPILLLLPELQKPLFPQSNLLISKGKCFFVCQCILAFSGIICKVFWMNKGKIIHLIFYALLGWSGLLLVPAMWKANIFHFVLLGGVFYSLGIYFYVKDNKKYFHFIWHLFVMAGTCFHAWGIYRLLEILPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR67</accession>
    <name>Q6YR67_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YlxR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_149"/>
    <dbReference type="EnsemblBacteria" id="BAD04234">
        <property type="protein sequence ID" value="BAD04234"/>
        <property type="gene ID" value="PAM_149"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_149"/>
    <dbReference type="eggNOG" id="COG2740">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_147970_2_1_14"/>
    <dbReference type="OMA" id="RTCIVSK"/>
    <dbReference type="OrthoDB" id="2067975at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-181-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007393">
        <property type="entry name" value="DUF448"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037465">
        <property type="entry name" value="YlxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035931">
        <property type="entry name" value="YlxR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34215">
        <property type="entry name" value="PTHR34215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04296">
        <property type="entry name" value="YlxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64376">
        <property type="entry name" value="SSF64376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YlxR" evidence="1">
        <location>
            <begin position="5"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="85" mass="9747" checksum="D6113368794A87A3" modified="2004-07-05" version="1">MTVLRTCIVSKKIQDIKKMIRINSTKQGKVAVDFNLALQGRGAYLTLKLEYVILSQKKKLLDKKLKTKVPEEIYQTLLKLIALQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="113" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR68</accession>
    <name>Q6YR68_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription termination/antitermination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">nusA</name>
        <name evidence="10" type="ordered locus">PAM_148</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates in both transcription termination and antitermination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NusA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_148"/>
    <dbReference type="EnsemblBacteria" id="BAD04233">
        <property type="protein sequence ID" value="BAD04233"/>
        <property type="gene ID" value="PAM_148"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_148"/>
    <dbReference type="eggNOG" id="COG0195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029242_2_2_14"/>
    <dbReference type="OMA" id="RIPGERC"/>
    <dbReference type="OrthoDB" id="384865at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-180-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_B">
        <property type="entry name" value="NusA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039566">
        <property type="entry name" value="CvfB_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036555">
        <property type="entry name" value="NusA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013735">
        <property type="entry name" value="TF_NusA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010213">
        <property type="entry name" value="Tscrpt_termination_fac_NusA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08529">
        <property type="entry name" value="NusA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13509">
        <property type="entry name" value="S1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69705">
        <property type="entry name" value="SSF69705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01953">
        <property type="entry name" value="NusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NusA_N" evidence="7">
        <location>
            <begin position="6"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="S1_2" evidence="9">
        <location>
            <begin position="141"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="KH_5" evidence="8">
        <location>
            <begin position="237"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="357" mass="40356" checksum="E818460C38D8E37C" modified="2004-07-05" version="1">MISKNFFKLLDKIAQERDLDKDQVIDAFAKGLISGCKKNHKVKSCKIELKEDKSEIILYKQFLVADEATMSTINLKESTPITLEEAQQIKPHAKIGQVIDIKVDPKDFNLYAVKELKNQFNEELTKKKRESIYNFFKQQEGKLISAKIISENDKFYNLELEKEITTLLPKKEIASNNEMQVGERIQVFLSEVRKTTKWPKIFVSCNHVGLVVKVLEENIPEIQEGIVKIAGVARISGERTKIGLLSCDAQVDAIGSCIGERSNRIKNVIKILKDEKVDLFVWSDDPQELIANALKPASCLQVVIKDDINKYALAIVPDDQFSLAIGKLGKNVKLAVEVTKWNIDIKTLDQAQTEGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR81</accession>
    <name>Q6YR81_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_135"/>
    <dbReference type="EnsemblBacteria" id="BAD04220">
        <property type="protein sequence ID" value="BAD04220"/>
        <property type="gene ID" value="PAM_135"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_135"/>
    <dbReference type="eggNOG" id="COG3870">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143974_0_0_14"/>
    <dbReference type="OMA" id="TFMIGIE"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010375">
        <property type="entry name" value="CdAMP_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38456">
        <property type="entry name" value="PTHR38456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06153">
        <property type="entry name" value="CdAMP_rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="110" mass="12244" checksum="B48BF59B9180C2E4" modified="2004-07-05" version="1">MDNMKLIIAIVSSHDANKVQQSLIENSFFTTRLATKGGFLKEANATFILGVKEEQVPKALEIIKAHSHKKTQMIPKNIINEFSAYNSFPTEVSVGGATIFVLDVYQFLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="124" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR84</accession>
    <name>Q6YR84_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized ABC-type transport system ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">abc</name>
        <name evidence="5" type="ordered locus">PAM_132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_132"/>
    <dbReference type="EnsemblBacteria" id="BAD04217">
        <property type="protein sequence ID" value="BAD04217"/>
        <property type="gene ID" value="PAM_132"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_132"/>
    <dbReference type="eggNOG" id="COG1135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_14"/>
    <dbReference type="OMA" id="RMKDFDA"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015821">
        <property type="term" value="P:methionine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026253">
        <property type="entry name" value="ABC_MetN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43166:SF5">
        <property type="entry name" value="PTHR43166:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="203" mass="22531" checksum="8D67FCB36296FEB9" modified="2004-07-05" version="1">MKGEIFGLVGTSGSGKTTLLKIMNGFMLPDKNANSSMQKAFSHLESAMIFQNFNLLSNLNVFENVALPLEIRSTPEEQITTKVNKMLDFVGLRQFATAYPKTLSGGQKQRVAIARALVYEPKIIFCDEPTFALDEMTSQEILKLLQTTNQKLKTTIVLVSHNVAVIKSLCHRVAILEQGKLAKIATLNPSCKFEATSYQNIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR85</accession>
    <name>Q6YR85_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rluA</name>
        <name evidence="5" type="ordered locus">PAM_131</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_131"/>
    <dbReference type="EnsemblBacteria" id="BAD04216">
        <property type="protein sequence ID" value="BAD04216"/>
        <property type="gene ID" value="PAM_131"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_131"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_4_4_14"/>
    <dbReference type="OMA" id="AHPSPGW"/>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-163-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="16"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="303" mass="34546" checksum="F31B6258D3DB5750" modified="2004-07-05" version="1">MNEKKEFLISASEAFQRLDHFLLTHINLNKSQCQKLILAQQVLVNSKPAKKSYLLKAQDLITVIIPQTQESVNLQTPQNLNLDIIYEDPYLAVINKPANLVAHPSLSFQETTLVNGLLYQFATLSHVDTQRPGIVHRLDKNTTGLLIIAKNNDVSDKLQIAFQQRKITKIYWALIEGFLEDKGTIKLPIGRNPHNRLKMQVIPDGKTAVTHFKTLQRFSHFSLMEFNLETGRTHQLRAHFSFLKRPIIGDLLYGSSHHITPLGQFLHAKMLKFNHPITNQNLILEAPLPANFEKLLQSLNNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRA0</accession>
    <name>Q6YRA0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_115"/>
    <dbReference type="EnsemblBacteria" id="BAD04200">
        <property type="protein sequence ID" value="BAD04200"/>
        <property type="gene ID" value="PAM_115"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_115"/>
    <dbReference type="HOGENOM" id="CLU_1314374_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-147-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="209" mass="24837" checksum="975C5D70FA834D0E" modified="2004-07-05" version="1">MQQTLQEYLEYQKKQIKDKINNIIKKFTTGINAPYFTFNLSNKKIKWYSGSLYYDSIKELEKYLENMTYKATLPTIDSNLTLSFKTKQKENELKEVDYAYYDLVNNDNQVNNNMSVILRFRPFVAPFCLDEKKQEQACKNCTTCQSNSCQDEKDKLKPCEQLKTGFGAWLSPQDCLGEIQQELKNKMIMHHHNKEKQSFYFLKNQYIIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRC3</accession>
    <name>Q6YRC3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type Mn/Zn transport system, periplasmic Mn/Zn-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">znuA</name>
        <name evidence="3" type="ordered locus">PAM_092</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_092"/>
    <dbReference type="EnsemblBacteria" id="BAD04177">
        <property type="protein sequence ID" value="BAD04177"/>
        <property type="gene ID" value="PAM_092"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_092"/>
    <dbReference type="eggNOG" id="COG0803">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016838_1_1_14"/>
    <dbReference type="OMA" id="DPHIWFD"/>
    <dbReference type="OrthoDB" id="1703187at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-123-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="381" mass="43501" checksum="6E2F6ED55132CB2E" modified="2004-07-05" version="1">MDFFIKHKQKTIIFLLATITTLILSIPFLSLTKANNAKTASKDLQIVTTTTMLKDLVKHLVGDVAEEEQNEYQKIEGIQVDSLMGVGIDPHNYKTKLSDRKKIKEVDLVVINGLHLEAKMAEAFPLLTNNSFTVVQLDETHTKVINQEGKEEERIKEENIKRDEDTHGPDPHIWFDIDLWIKVLKQLKYKLKTVLKKDLRFSQRDIANLKNNCDTYARKLKLLDTYVGKKFNELKGQFSSQGKTFILVTAHDAFSYLARKYDFELSPIQGISTQTEASISDIEELANKLVENQVKAIFVESAFPEGTLDSLKESVKIKGHNIKKSDEELYADALGSESEEPIEFEADKDKDGNYKPTKYKHSTYIGALLHNIHTIEKELKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRD8</accession>
    <name>Q6YRD8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type amino acid transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">artM</name>
        <name evidence="8" type="ordered locus">PAM_077</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_077"/>
    <dbReference type="EnsemblBacteria" id="BAD04162">
        <property type="protein sequence ID" value="BAD04162"/>
        <property type="gene ID" value="PAM_077"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_077"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_741539_0_0_14"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-105-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="257"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="83"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="373" mass="43087" checksum="0F2E37EFDBACE4F1" modified="2004-07-05" version="1">MKQLKKVVDTLTKCLKGGTQRQTFKTNYDKLKVKKSYKFSSTPEEKNKNQERTLDEEQEYQFLKKYLFAFFDETKEAKTRRVLNSKQQELEVSQKEKETLEKCLDEQDKTQLEQVKKKYEELNTKNQRNAAQEQEFVELNKTTRAQTATENDSPDVQKYEHLTSKKEAIKNKIDERLKVVFDETVYNEKGFVQKGDDSLWGKIKYHLPTYKKPFYTSLLLAVYVFVFGFLLSLVLLAVKNKSTLSRTNNVFVKGVKQVGSKFVDKGQVEAAQSLGLNKKQTFYYVTFPQALKKSVPLVVAQFVTNIKACTFFVLIALIDMSFVTNDAMNVTGDLVAPFVILSFVYLVLIQFINMLSKYLEKKLNPALKTLVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRE3</accession>
    <name>Q6YRE3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thymidylate_kin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_072"/>
    <dbReference type="EnsemblBacteria" id="BAD04157">
        <property type="protein sequence ID" value="BAD04157"/>
        <property type="gene ID" value="PAM_072"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_072"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1946601_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-96-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="1">
        <location>
            <begin position="7"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="129" mass="14965" checksum="4022D817454B0C08" modified="2004-07-05" version="1">MKLIVFEVLDGSGKTSLIHALQPQLKAPFQTYQGLGSSSLGKEIRDLFLNFSQVDYLTRFYLSLANMTQNQVELIVPQLKNNQLIILDRWLPSTYAYQLFPFSKEKKQLLPLKKIFKLNHETILKNLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRF0</accession>
    <name>Q6YRF0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_065"/>
    <dbReference type="EnsemblBacteria" id="BAD04150">
        <property type="protein sequence ID" value="BAD04150"/>
        <property type="gene ID" value="PAM_065"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_065"/>
    <dbReference type="HOGENOM" id="CLU_2437954_0_0_14"/>
    <dbReference type="OMA" id="EMIINQN"/>
    <dbReference type="OrthoDB" id="2189769at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-86-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="90" mass="10976" checksum="73C06898258E37C8" modified="2004-07-05" version="1">MEMHKKHFIYIYLIIVVTSIITTYNFVNHNNLEKHINLQNNHLKEKINLIEKEMDEFQQETQNNFKKINEKIDKLEEMIINQNKSNQESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRG0</accession>
    <name>Q6YRG0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="5">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nrdF</name>
        <name evidence="6" type="ordered locus">PAM_055</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="5"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_055"/>
    <dbReference type="EnsemblBacteria" id="BAD04140">
        <property type="protein sequence ID" value="BAD04140"/>
        <property type="gene ID" value="PAM_055"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_055"/>
    <dbReference type="eggNOG" id="COG0208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052495_1_0_14"/>
    <dbReference type="OMA" id="IGYKYQR"/>
    <dbReference type="OrthoDB" id="1384440at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-71-MON"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005971">
        <property type="term" value="C:ribonucleoside-diphosphate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026494">
        <property type="entry name" value="RNR_NrdF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="PTHR23409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04171">
        <property type="entry name" value="RNR_1b_NrdF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="350" mass="40900" checksum="FD4DD88222E240BC" modified="2004-07-05" version="1">MKTKNSQPHPTSKSPFQGANWNVLEDKYTHFFYEQNLSQFWRPEDISLQGDLAAWSELTLEEKTAYSRNLLVLTFLDTYQGDLGMPVIARSLEEHEHQKKATLNFMGAMENAVHAKSYSNIFMSYLTNKEINQLFLWGNQQTSLQTMMQVIVKVYEALEDQIYLKKQSSLQFSELEFKKTQWQAMAVSVFLETWLFYSGFYYSLYFYGQGKLMQSGEIINLIIRDESIHGVYVGRLATEIYQLFDKPTQQTLKTWLDDLMQQLYQAQTSLVHAIYHKLNLEDDVNKFVRYNANKALMNLGFDAFFPSENVNPVIINGLNTETKTMDNFSMKGNGYQKMRSEALQDEDFYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRG9</accession>
    <name>Q6YRG9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_046"/>
    <dbReference type="EnsemblBacteria" id="BAD04131">
        <property type="protein sequence ID" value="BAD04131"/>
        <property type="gene ID" value="PAM_046"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_046"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_959212_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-62-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="281" mass="31921" checksum="8F2D58BB10C9A41B" modified="2004-07-05" version="1">MAKKTNKNTKNQSKNNKSNEIIIKRKTLTPKIIIETQTKKEKWFLKIIKTFFNILIWFIPLLLIGGAFYWTLFKFFPEVLNQINTFTGDAAAKTKALYDKATQPIRQVIEYIYNKLTGKNKDPNHIPSPQNKLGYYLATTLSVVGICLGFGKIGNWLKNGKKKTIKKGTKTIIQKKATSKIANIGGKILKIGSKALFWVSLASTAYEIYQFYHEETKTPNPPQQLTHKMENPPTPILQTPSIPQSFNPTIIENEESTLTNNNEVKEKTTQEESKTGNLNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRI0</accession>
    <name>Q6YRI0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_035"/>
    <dbReference type="EnsemblBacteria" id="BAD04120">
        <property type="protein sequence ID" value="BAD04120"/>
        <property type="gene ID" value="PAM_035"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_035"/>
    <dbReference type="HOGENOM" id="CLU_2082424_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-50-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="117" mass="13520" checksum="17AEDF70A56005B6" modified="2004-07-05" version="1">MRTKDVGIVDASKLQFNTSLQSLFSLGNTEDTEETENTKEKTEKYIEFRTNLYKDFPNIQNTQFLTEQKNIFLQLLFPLDKMAQEFLQNIASDNNSNNNDFVKAKDALIICGKKIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRI2</accession>
    <name>Q6YRI2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_033"/>
    <dbReference type="EnsemblBacteria" id="BAD04118">
        <property type="protein sequence ID" value="BAD04118"/>
        <property type="gene ID" value="PAM_033"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_033"/>
    <dbReference type="HOGENOM" id="CLU_1720487_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-45-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="152" mass="18484" checksum="FA180174BD8A6B48" modified="2004-07-05" version="1">MSPKGTVWQGVWKNQVKEEFRDNFKGKEDIIKKTFETNKPDKLEAFCNVFYDENTFNQYFIENFHVLQINQTNELYVYEQDLDKNYLYHKLYKQYKLFQELKKECSNLLNYKENKLMPAQNKLEAFESNLTNKTSTTKKEQQEKEQKNKTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRI3</accession>
    <name>Q6YRI3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04117">
        <property type="protein sequence ID" value="BAD04117"/>
        <property type="gene ID" value="PAM_032"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_032"/>
    <dbReference type="HOGENOM" id="CLU_1276556_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-43-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="216" mass="25780" checksum="186580E4AE456E91" modified="2004-07-05" version="1">MQNIPNSFKELVQEEQKTLKSEIRDLIGKSISTHENNDELTDEERKQHEQYKKNKKESESKLSNKEWGFEVLDSLLNGNNYDNMSSIDSQFNKLKSVLESCSQTYYFDPKTLSSAQDNFVETIKTFKNNYSKHNSECQGFINKINSLVEEFKAIQERIINNIIMLRKKFEYRFFYIAKQKLKFYKQEVQKHLQQIKKELQAFKEQTIPLKQYCNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRI4</accession>
    <name>Q6YRI4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04116">
        <property type="protein sequence ID" value="BAD04116"/>
        <property type="gene ID" value="PAM_031"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_031"/>
    <dbReference type="HOGENOM" id="CLU_743239_0_0_14"/>
    <dbReference type="OMA" id="YIPLMPE"/>
    <dbReference type="OrthoDB" id="707588at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-41-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="376" mass="43131" checksum="49D1124C844BCCF6" modified="2004-07-05" version="1">MISKIPKLFWTNIAIIIFVIIGIKEFIDLPKKLSIDLNTNPTHIICDVVPVGACFTKPSINMSLKKHHLSSAKPHYNIYTDEKYIPLMPELLETQLMKEGKEHRDNKVMQIAIQAKEHQNKKFNCSIFQEEKKFLREIQPNGIIIEGFLDSCLLTQVILPSGSIFKYYMPTQDNIQTIKEIWCANGQILKPDFSNILHFSMMQTPTPLTPSQLTAYHEAGHALIVLQFPFALCSVAKIYIQETTTDLNADSMFFFGQTVVRHPKLNQGWQRLVLQAFGGAAAQQYLANQGKIPKEKIFSGIEDDFQFIEKLLMENNQLNKVDLNKLFQQAYNIVANNKDLLDIIAQEIDQKKFLQQIDIERIIKDNHMLVAKLRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="124" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRI9</accession>
    <name>Q6YRI9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type dipeptide/oligopeptide transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dppD</name>
        <name evidence="6" type="ordered locus">PAM_025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_025"/>
    <dbReference type="EnsemblBacteria" id="BAD04110">
        <property type="protein sequence ID" value="BAD04110"/>
        <property type="gene ID" value="PAM_025"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_025"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_14"/>
    <dbReference type="OMA" id="RVNVMYL"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-33-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="345" mass="38841" checksum="6258727AB5177360" modified="2004-07-05" version="1">MKKEILKICDLNLNFRVKKHLIYALRGINLSLGEGEILGLVGESGSGKSVISKALMGLLPDNALIQKGSILYKDLDLAQMKDKQFNKIRGNKISIIFQNPLSSLNPLIKVGKQIYESLQLKKTKSTHQQRKNQVLKLMEEVGIPEPMKRFNQYPHQLSGGMCQRIVIAIALANEAKILICDESTTALDVSVQKKILDLIKKLQKEKKLSIIFITHDLEVVKYVADRIAVIYAGRIVEYGTTHEVFYNSKHPYTWALLQSMPVFAKKGNKLKSIQGNPHLLTAPILGDAFAPRNPYALKIDFEKEPPMFKISATHYASSWLLHKFAPRIEVPDLILELQKKGGCCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRK7</accession>
    <name>Q6YRK7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Folylpolyglutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">folC</name>
        <name evidence="7" type="ordered locus">PAM_007</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_007"/>
    <dbReference type="EnsemblBacteria" id="BAD04092">
        <property type="protein sequence ID" value="BAD04092"/>
        <property type="gene ID" value="PAM_007"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_007"/>
    <dbReference type="eggNOG" id="COG0285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015869_1_1_14"/>
    <dbReference type="OMA" id="KCDYAVI"/>
    <dbReference type="OrthoDB" id="1232874at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-10-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="6">
        <location>
            <begin position="133"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="5">
        <location>
            <begin position="303"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="438" mass="50021" checksum="724776CB2E7FBC3F" modified="2004-07-05" version="1">MITEITNIKEAILWIEKREILGMRLGLLRVLALLKLLHHPEKKLAMIHIAGTNGKGSTVNYLSSLLQQSCSKVGTFISPHIQNYNERIKINGETISCNDLIIWVRKIKKLVDQASPNSALFSITPFEIITAIAFDYFYHKKVDVCVIEVGLGGLLDSTNVIYPILTGITTIGKDHEHILGKTLKEIAFQKAGIIKPKIPLVTGNISPKALLVIEQQAIKNKTPIYKFKKDYNITYLGMQTWQECFNFKTKQITIKAIKTPLIGKYQPENAAMAIKLYYLFCQLKKFPFLEQNVFTGISKTQIPARMQKLNSNPLIILDGAHNVHAIRKLVQTTIKQFSNYRISILFSALENKNVVSMLYQLLKIPKAHIYLTTFNHPNSIELVQKYLFIAPQRITKVFDWQDKLKDFLQQNQTQNCKDLLLIIGSLYFASEVIHFFDI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-02-16" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>Q8G8D1</accession>
    <name>REPP_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName>Replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">rep</name>
        <name type="ordered locus">PAM_790</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid">
        <name>pOYM</name>
    </geneLocation>
    <geneLocation type="plasmid">
        <name>pOYNIM</name>
    </geneLocation>
    <reference key="1">
        <citation type="journal article" date="2002" name="Gene" volume="298" first="195" last="201">
            <title>A plasmid from a non-insect-transmissible line of a phytoplasma lacks two open reading frames that exist in the plasmid from the wild-type line.</title>
            <authorList>
                <person name="Nishigawa H."/>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Jung H."/>
                <person name="Kuboyama T."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="12426107"/>
            <dbReference type="DOI" id="10.1016/S0378-1119(02)00975-7"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
            <strain>OY-NIM</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Is essential for plasmid replication. Nicks the positive strand at the plus origin of replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Gram-positive plasmids replication protein type 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AB061723">
        <property type="protein sequence ID" value="BAC23024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AB061724">
        <property type="protein sequence ID" value="BAC23025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002600752.1">
        <property type="nucleotide sequence ID" value="NC_012089.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002600757.1">
        <property type="nucleotide sequence ID" value="NC_012090.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959604.1">
        <property type="nucleotide sequence ID" value="NC_019170.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959608.1">
        <property type="nucleotide sequence ID" value="NC_019171.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959611.1">
        <property type="nucleotide sequence ID" value="NC_019172.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959614.1">
        <property type="nucleotide sequence ID" value="NC_019173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q8G8D1"/>
    <dbReference type="OMA" id="MECIFIT"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Plasmid pOYM"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005727">
        <property type="term" value="C:extrachromosomal circular DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003916">
        <property type="term" value="F:DNA topoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000605">
        <property type="entry name" value="Helicase_SF3_ssDNA/RNA_vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002631">
        <property type="entry name" value="Plasmid_rep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01719">
        <property type="entry name" value="Rep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00910">
        <property type="entry name" value="RNA_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0614">Plasmid</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000068329" description="Replication protein">
        <location>
            <begin position="1"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="204"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="377" mass="44377" checksum="D969193130C4FA83" modified="2003-03-01" version="1">MKLRICELVINKTLITKTKIETILETKKKAIQNYAYILHDKDIYQNEKEAQLNGKKVGDIKAPHWHIYLRFNYSQDTKHISQWFNTQENFVSKIKGRFSDALMYMIHANRLDKHQYDEKEVVSNFDWKSEAQQDIFNRKYKMDARLKDILLKIHSGEIKEYNINDNINILENNIYATAIEKAFKFRIRDLKKKVRQMECIFITGLSGSGKSTLAKKIAEDKNYEAYISSGSNDILDDYCGEECIILDDLRSNCLGLSDLLKMLDNNTASSVKSRYKNKVLECQLIIITTVKSIDDFFEDIFRKDESIIQLKRRCKLHIKIDSKYIYYSVWNPIEMKYDLIEKKPNNLLNDFQIKSLSKKEAKDYIKSISNIDLDKDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-02-05" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A9JR03</accession>
    <name>A9JR03_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAF95571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_761"/>
    <dbReference type="EnsemblBacteria" id="BAF95571">
        <property type="protein sequence ID" value="BAF95571"/>
        <property type="gene ID" value="PAM_761"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_761"/>
    <dbReference type="HOGENOM" id="CLU_2554955_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-511-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF95571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="82" mass="10158" checksum="51BCF1968D7611DB" modified="2008-02-05" version="1">MWNLINTWLTKLNNVLNTISHYFFTYQNQWLNLGLLTIILLFIPHLLYLIDFLFKCLYHILRFIYYLGKYLLLLLKKIFKKE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-02-16" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>P60397</accession>
    <name>RSMH_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="1">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmH</name>
        <name type="synonym">mraW</name>
        <name type="ordered locus">PAM_735</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04820" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04820.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P60397"/>
    <dbReference type="SMR" id="P60397"/>
    <dbReference type="STRING" id="262768.PAM_735"/>
    <dbReference type="EnsemblBacteria" id="BAD04820">
        <property type="protein sequence ID" value="BAD04820"/>
        <property type="gene ID" value="PAM_735"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_735"/>
    <dbReference type="eggNOG" id="COG0275">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038422_2_0_14"/>
    <dbReference type="OMA" id="NPAKRTF"/>
    <dbReference type="OrthoDB" id="1272633at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-890-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000108675" description="Ribosomal RNA small subunit methyltransferase H">
        <location>
            <begin position="1"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="36"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="304" mass="34555" checksum="3ED3D07553F47CC5" modified="2004-02-16" version="1">MNKTHFNHISVLKQEAIDFLKIKPEGIYVDATLGQCGHTIEIANLLQQGFLYSFDQDVEACTNAKKILPPHLPIEIIHSNFSHLKTQLAQRNVFQLDGILFDLGLSSCQIDNPQRGFSYLHNTPLDMRMNVNQTITAQYILNNYSFAQLKNIFKVYGEVKNAALVASEIIKQRPLCTSYDLVAITDRFCNRQKGHSAKKIFQALRIEVNQELESLKQALEQSLDLLKPNAMIVVISFHSLEDRIVKHFFKKNSTFVLPKKMPITIMPQTPLSIITKKAFLPSEEEMQNNSRSISAKLRVAVKNG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-06-07" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>P61692</accession>
    <name>IF1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">infA</name>
        <name type="ordered locus">PAM_223</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IF-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P61692"/>
    <dbReference type="SMR" id="P61692"/>
    <dbReference type="STRING" id="262768.PAM_223"/>
    <dbReference type="EnsemblBacteria" id="BAD04308">
        <property type="protein sequence ID" value="BAD04308"/>
        <property type="gene ID" value="PAM_223"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_223"/>
    <dbReference type="eggNOG" id="COG0361">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_151267_4_0_14"/>
    <dbReference type="OMA" id="AHVSGKM"/>
    <dbReference type="OrthoDB" id="2066663at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-269-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0396">Initiation factor</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000095837" description="Translation initiation factor IF-1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="S1-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <sequence length="78" mass="9062" checksum="7363D2795CC0DB71" modified="2004-06-07" version="1">MSKNNLNETESKIEIEAKVVELLSNDKFKVELPNKKTIIAYVSGKIRINNIRILPGDKVRIELSPYDPTRARITYRFK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-07-05" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>P62235</accession>
    <name>RS16_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsP</name>
        <name type="ordered locus">PAM_472</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P62235"/>
    <dbReference type="SMR" id="P62235"/>
    <dbReference type="STRING" id="262768.PAM_472"/>
    <dbReference type="EnsemblBacteria" id="BAD04557">
        <property type="protein sequence ID" value="BAD04557"/>
        <property type="gene ID" value="PAM_472"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_472"/>
    <dbReference type="eggNOG" id="COG0228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100590_5_2_14"/>
    <dbReference type="OMA" id="GFYNPIA"/>
    <dbReference type="OrthoDB" id="1937072at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-557-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000167219" description="30S ribosomal protein S16">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <sequence length="87" mass="10081" checksum="74FACFB8885DFB47" modified="2004-07-05" version="1">MAIKMRLQRFGVHKRPFYRVVASESKNARDGKFLEILGTYDTILDIVELDHNKVQKWLSNGAQPTKTVKKVFKKSKFVAKTNTKVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPI6</accession>
    <name>Q6YPI6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_741"/>
    <dbReference type="EnsemblBacteria" id="BAD04826">
        <property type="protein sequence ID" value="BAD04826"/>
        <property type="gene ID" value="PAM_741"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_741"/>
    <dbReference type="HOGENOM" id="CLU_1314375_0_0_14"/>
    <dbReference type="OMA" id="FTGIKQF"/>
    <dbReference type="OrthoDB" id="1702476at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-896-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="209" mass="24151" checksum="B5041AE0DCD2696C" modified="2004-07-05" version="1">MNQMKQKRLQGFYSLLLATFFLLVAGCCFFDQTFQLGSLKFQLGLFFLGVLLSLFTYLVVFKKYKKTLSKLRFFFALEAFVFVFVIVTAFLLPGLGFLNIDDLKTKNPLVGKLLTFNYCLSLMFVLHSFINLNINYFKKQNFSFFILYLLMFGFGCFGLGSNLFENLKDIILKSFAVLSLMHSIYLTFTGIKQFQTASLHAPKKENENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="132" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPI9</accession>
    <name>Q6YPI9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="9">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 14" type="primary">leuS</name>
        <name evidence="14" type="ordered locus">PAM_738</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="9"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_738"/>
    <dbReference type="EnsemblBacteria" id="BAD04823">
        <property type="protein sequence ID" value="BAD04823"/>
        <property type="gene ID" value="PAM_738"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_738"/>
    <dbReference type="eggNOG" id="COG0495">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004427_0_0_14"/>
    <dbReference type="OMA" id="TFMVLAP"/>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-893-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="12">
        <location>
            <begin position="43"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="13">
        <location>
            <begin position="227"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="673"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="599"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="602"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAD04823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="821" mass="95268" checksum="805A7D5DFB007663" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPK0</accession>
    <name>Q6YPK0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_725"/>
    <dbReference type="EnsemblBacteria" id="BAD04810">
        <property type="protein sequence ID" value="BAD04810"/>
        <property type="gene ID" value="PAM_725"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_725"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_41_1_14"/>
    <dbReference type="OMA" id="ACINVKE"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="163" mass="19161" checksum="6AD092BB37AA2CFF" modified="2004-07-05" version="1">MATKPLQKLFTDITYFKTNQGFLYFSCIIDSFNNQIITSHVSNQQNKDLVLNTIKKLPSLKEPCIIHSDQGKVYQSLKIQQTLIKKGFLISMSRKATPRDNAIIENFFGQMKTILQHQNPFLFQKSPDKMKKLINHFLKFWNNQWILSKLNYSTPSQYIQNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="121" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPK4</accession>
    <name>Q6YPK4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Malic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sfcA</name>
        <name evidence="9" type="ordered locus">PAM_721</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="5">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_721"/>
    <dbReference type="EnsemblBacteria" id="BAD04806">
        <property type="protein sequence ID" value="BAD04806"/>
        <property type="gene ID" value="PAM_721"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_721"/>
    <dbReference type="eggNOG" id="COG0281">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034446_2_1_14"/>
    <dbReference type="OMA" id="HKYAAVV"/>
    <dbReference type="OrthoDB" id="654531at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-873-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05311">
        <property type="entry name" value="NAD_bind_2_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045213">
        <property type="entry name" value="Malic_NAD-bd_bact_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="8">
        <location>
            <begin position="15"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="7">
        <location>
            <begin position="160"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="390" mass="41715" checksum="DA1A6174701A6EFD" modified="2004-07-05" version="1">MNIKEKALEIHEKNKGKVGIVSKVKVQNLDDLALAYTPGVAEPCLKIKENPSDVYRYTMKGNMVGVVTNGTAVLGLGNIGPKASLPVMEGKAILFKELAGIDSFPICIDSTDSQEIVNIVSKISTVFGAINLEDIKSPQCIEVEDALEAKLDIPVFHDDQHGTAIVVAAGILNSLKVVKKSIEDVQVVINGAGSAGMAIAKMLLLLKVNNIVLVDKTGALYKGVANLNEPQKKLVEVTNKYQEKGTLKEVLKGKDIFVGVSAPGIVTAEMVSTMAKDAIVFALANPVPEIMPDEAKKGGARIVATGRSDFPNQVNNCLAFPGVFRGALDAKATKITEEMKKAAIYALKNIIKEQDLNENNILPTSFNKEVVKQIALAVCKVAKETGVVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-12-02" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPK5</accession>
    <name>Q6YPK5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Malate/citrate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">citS</name>
        <name evidence="2" type="ordered locus">PAM_720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_720"/>
    <dbReference type="EnsemblBacteria" id="BAD04805">
        <property type="protein sequence ID" value="BAD04805"/>
        <property type="gene ID" value="PAM_720"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_720"/>
    <dbReference type="eggNOG" id="COG3493">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041211_0_1_14"/>
    <dbReference type="OMA" id="NMGGTGD"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008514">
        <property type="term" value="F:organic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004679">
        <property type="entry name" value="2-OHcarboxylate_transport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40033">
        <property type="entry name" value="PTHR40033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03390">
        <property type="entry name" value="2HCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="371" mass="39997" checksum="06F6464034A49715" modified="2004-07-05" version="1">MKHLNAESITVKETQYTYKAIGFASFFVSALIIGSFLSMDKKLLKSSFKKFIPLILVSLLTGALVVGTLGALLNPIGGLENASQTSKGGFLDAVFYIFAPLASGGMSSGVTPLKNAYAGQNLDWQEPFMSHMTPALLVGGIFSIFASGLIKKFLKTTKYSGYGKLEVKETPKNPDKNTSKSVPEKLSYPQITTGLIAIFTLYLLSVLIKESLILLLPNIKKYLPEYIVFLVFVVVLMKLFNVVSDYYNSCINQASKFVTTNFTSAFLVILGSSIPMEDMLKQLNIKFVFTCIMCVLSVALVAGYLGKKLGYYPVESSITAGLCTNSIGGAGNVAILSASDLMGLMPFAQIATRIGGALVVVVASIAYPLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPL5</accession>
    <name>Q6YPL5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_710"/>
    <dbReference type="EnsemblBacteria" id="BAD04795">
        <property type="protein sequence ID" value="BAD04795"/>
        <property type="gene ID" value="PAM_710"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_710"/>
    <dbReference type="HOGENOM" id="CLU_1775562_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-865-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="146" mass="17182" checksum="7BB897CFFE49EECF" modified="2004-07-05" version="1">MNFSKQQIKIILFILILSLLTGFAFYFTYKHLNKDLNKNETQNQKTPQTTKYKELSNPHQKIKNIISKINIFISENDPQIKEAKTQNTNQRIQYEESNYPNKVEINLINKIKDLFEDLFESLSLSLTDASNPFEITETLKSNPQFF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-04-26" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPM2</accession>
    <name>DNAJ_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName>Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">dnaJ</name>
        <name type="ordered locus">PAM_703</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DnaJ family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPM2"/>
    <dbReference type="SMR" id="Q6YPM2"/>
    <dbReference type="STRING" id="262768.PAM_703"/>
    <dbReference type="EnsemblBacteria" id="BAD04788">
        <property type="protein sequence ID" value="BAD04788"/>
        <property type="gene ID" value="PAM_703"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_703"/>
    <dbReference type="eggNOG" id="COG0484">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_0_7_14"/>
    <dbReference type="OMA" id="DLHCTVT"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_0000070845" description="Chaperone protein DnaJ">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="5"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif">
        <location>
            <begin position="141"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif">
        <location>
            <begin position="158"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif">
        <location>
            <begin position="184"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif">
        <location>
            <begin position="198"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="257" mass="28229" checksum="4653FA44EC9650EC" modified="2004-07-05" version="1">MTKKDYYHILGLDKDASPEDIKKAYRSLAKKYHPDISKEANAENKFKEVQEAYSVLGDASKKSNYDRFGDASDNGFSGFGGGGFDGFDSFGDSFFSSFGDIFGNQQTKKPSYDKKVEMTISFMDAVLGANKTIEITVEADCRVCHGKGAVSNQDVITCKRCGGNGQIITEQRTFLGNIRSRQVCPNCSGKGQEIKNKCYACHGQKRQKVKQSATFNIPAGIQEGMSLQVPGKGNFVPLSNNQKRRRSILLTFNSASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPN5</accession>
    <name>Q6YPN5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_690"/>
    <dbReference type="EnsemblBacteria" id="BAD04775">
        <property type="protein sequence ID" value="BAD04775"/>
        <property type="gene ID" value="PAM_690"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_690"/>
    <dbReference type="HOGENOM" id="CLU_2476660_0_0_14"/>
    <dbReference type="OMA" id="FFITNNH"/>
    <dbReference type="OrthoDB" id="1869704at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-841-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="87" mass="10386" checksum="05EB333457F3D165" modified="2004-07-05" version="1">MLIFRLKKQLYLLIIVLFTFLGLFFITNNHQVMAMEKNKPLQTIYNIETKNVRINPNKPIKISYYVKDKNLSLEDMVKNINIINKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPN8</accession>
    <name>Q6YPN8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_687"/>
    <dbReference type="EnsemblBacteria" id="BAD04772">
        <property type="protein sequence ID" value="BAD04772"/>
        <property type="gene ID" value="PAM_687"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_687"/>
    <dbReference type="eggNOG" id="ENOG5033PU3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239554_0_0_14"/>
    <dbReference type="OMA" id="KTKRIMA"/>
    <dbReference type="OrthoDB" id="1398254at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-838-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.91.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038365">
        <property type="entry name" value="EcoRII_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="203" mass="24127" checksum="23E3E95D89B2E65D" modified="2004-07-05" version="1">MNQLNNLHFNNINVFNHQSLCVDITKLIIQPSLFNQPFNEYMTQTHNLLNEYLQNNHYNSQSQKSIRGKINEYLILLYLNNKGITHLYPQSHLFFIPDIKFDLVLFTKTKRIMAFNFKTCLRDRYKQAMIEGQQLKKLDTRFEFYLLTNNETETQRLNKKINQGKVQGINQVINLFSDSANKFLQNLLTNKFIPFSNINIIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPP1</accession>
    <name>Q6YPP1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_684"/>
    <dbReference type="EnsemblBacteria" id="BAD04769">
        <property type="protein sequence ID" value="BAD04769"/>
        <property type="gene ID" value="PAM_684"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_684"/>
    <dbReference type="HOGENOM" id="CLU_1319854_0_0_14"/>
    <dbReference type="OrthoDB" id="1617013at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-835-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="209" mass="24830" checksum="0645E654B660C356" modified="2004-07-05" version="1">MKNNTNQEIRIGGWETKTTPNDLVQIKNFLQTIKQELLNITIISHSKKKNTYQQANYRPKNQTLFVDPQILDEMKKYRIEIIKTHSPESDNNITTLTNHTNPPKSQNNTLKTHFPIFQINYSNKQKDFIKDLISKINIVKLDTLKLYKLDSQKRDKSNIPIKSNYKKGLNVIYYQLEDFKHIKIFLTKNKQGYRVKKIHPMYKYISKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPP5</accession>
    <name>Q6YPP5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Guanylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gmk</name>
        <name evidence="2" type="ordered locus">PAM_680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_680"/>
    <dbReference type="EnsemblBacteria" id="BAD04765">
        <property type="protein sequence ID" value="BAD04765"/>
        <property type="gene ID" value="PAM_680"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_680"/>
    <dbReference type="HOGENOM" id="CLU_1546075_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-830-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="173" mass="20351" checksum="D4DD2D7A429BA462" modified="2004-07-05" version="1">MGYLYVRLNISHTLDLTDKLLIHKHLCLTMLLSFIFILMSNFAITILLYYKKFKKQNNQQLINKFAFVVFNFFVITMFYVVLFYGVAFLWLASVSQLSQLSSLFDPYFMLVLLFVSLFISWASVYIAGALVVFGYIIEKQVDKKYEASMAFALFLLVFWPLIKALWNFCKKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPQ5</accession>
    <name>Q6YPQ5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04755">
        <property type="protein sequence ID" value="BAD04755"/>
        <property type="gene ID" value="PAM_670"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_670"/>
    <dbReference type="HOGENOM" id="CLU_1904615_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-816-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="133" mass="15787" checksum="7C3E38413FD0308F" modified="2004-07-05" version="1">MQNIKKYPKTIIAFFIKFILIITISSFLTPVFSNDGIDMDEQIKEYQKRRDNNKTLWEKIFNSAQHKQTITDSNVKVLQEALEINPDPINPDYKYIIKYRALDASGKVIWDSYQTYDLIFDSNYNVLKRYGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPR0</accession>
    <name>Q6YPR0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DhaL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_665"/>
    <dbReference type="EnsemblBacteria" id="BAD04750">
        <property type="protein sequence ID" value="BAD04750"/>
        <property type="gene ID" value="PAM_665"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_665"/>
    <dbReference type="eggNOG" id="COG1461">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017496_1_0_14"/>
    <dbReference type="OMA" id="TRTIPQG"/>
    <dbReference type="OrthoDB" id="1554133at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-810-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019986">
        <property type="entry name" value="DAK2_dom-cont_prot_YloV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033470">
        <property type="entry name" value="UPF_DhaK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13684">
        <property type="entry name" value="Dak1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01121">
        <property type="entry name" value="Dak1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03599">
        <property type="entry name" value="YloV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DhaL" evidence="1">
        <location>
            <begin position="13"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="571" mass="64889" checksum="ECD2736A16DDCFC6" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPR3</accession>
    <name>Q6YPR3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spermidine/putrescine-binding periplasmic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">potD</name>
        <name evidence="2" type="ordered locus">PAM_662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_662"/>
    <dbReference type="EnsemblBacteria" id="BAD04747">
        <property type="protein sequence ID" value="BAD04747"/>
        <property type="gene ID" value="PAM_662"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_662"/>
    <dbReference type="eggNOG" id="COG0687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_1_3_14"/>
    <dbReference type="OMA" id="FWMDNYA"/>
    <dbReference type="OrthoDB" id="1264541at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-807-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="408" mass="48049" checksum="458B51E1D380B9F9" modified="2004-07-05" version="1">MKKTIKTVATTLLFILTTTFVILIILNLKNKNILPQHQEEQTLTLFNWGEYLEPSIIEKFEKETHIKVKQVLFSSNELAVTKIKSKNQYDLAILSEYAIDQLRQSKMLETIDDGELIKDDKHYYELNKDLQDKLPSEFNNYAVPYFWGKVVILYNKNKITQDKINELKDQNKGFKYLKDTNLKVALCNNARDGLMVGLKATEGKIANPSPYELNEAKKWLLELKQQKPNLAFINDQLMDRMKNKNNEYYDIVIAYSGDANFLKEQNNNLDYFSPTEGTNVWVDALVMPKGSKKTLAYKFINFLRQKENYKNNLAFTKYNSPYVGLETFPGIRQIEIKVNDEVYKYDQTTQKTINTYWNDIIAFPSQKDYWLFILSFFIFLAIFIIYFHHKFKNKLRLDQLPQKIKTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPR5</accession>
    <name>Q6YPR5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type spermidine/putrescine transport system, permease component I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">potB</name>
        <name evidence="6" type="ordered locus">PAM_660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_660"/>
    <dbReference type="EnsemblBacteria" id="BAD04745">
        <property type="protein sequence ID" value="BAD04745"/>
        <property type="gene ID" value="PAM_660"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_660"/>
    <dbReference type="eggNOG" id="COG1176">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_18_3_14"/>
    <dbReference type="OMA" id="YPIAYGM"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-805-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="75"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="282" mass="32338" checksum="196E8E0581C0F95F" modified="2004-07-05" version="1">MVMKKTYTCKDNQKLYRLLISPYYIILLGLIILPMGFILFDSFQDTNQQNAFFATRFTLQHHQEFLSNQSFLYVLARSIAISIIVTFCVFIIVYPLAYMISRLKMKWQSFLVILINGTMWINMIIKTQALVQIFHLLQKTFNINLLETNFAMIVGLIYLFLPFMFLPIYTAIIKINPQLIQASKDLGANEWQILQKIIWPLSLSGVLAGICLVFLQTATNIVAPRYLGATTQITIAELIENKALLSGEIKQACAIAIHLSLTMFLIFQMFKKLSLGENKDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPS1</accession>
    <name>Q6YPS1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">himA</name>
        <name evidence="2" type="ordered locus">PAM_654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_654"/>
    <dbReference type="EnsemblBacteria" id="BAD04739">
        <property type="protein sequence ID" value="BAD04739"/>
        <property type="gene ID" value="PAM_654"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_654"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_3_14"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-799-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="96" mass="11031" checksum="03A987807712A8BC" modified="2004-07-05" version="1">MNKKELIKKIALANKTSVTKTEEFYNIFENTLIKAITTNEEVVLFPKIGKFKLKSRKSYIGRNPKTKKKIKISAKTVVTFKLSKTIKDQAKTLILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPS4</accession>
    <name>Q6YPS4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_651"/>
    <dbReference type="EnsemblBacteria" id="BAD04736">
        <property type="protein sequence ID" value="BAD04736"/>
        <property type="gene ID" value="PAM_651"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_651"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115275_0_0_14"/>
    <dbReference type="OMA" id="KPMKQLK"/>
    <dbReference type="OrthoDB" id="1592351at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-794-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="207" mass="24544" checksum="E9EC9177465AF288" modified="2004-07-05" version="1">MTEQLQNQLQEKKSLIETKNQELITNQALSQQEKQALQNEINQLTTNFQQKEKEYQATIYQKDQEITHLNQIINEQANEINRLSEELEQQIDKWVKQGLHIESLEGTIKALENVSSKYLEENAELRHEINKLKEQIKDEQKAHEATKVKLKENSDELTQKTTEYDKIKDTIKNQKTWKGSIQPFTTKIKDDVNKKVENVTSWFKKWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPS6</accession>
    <name>Q6YPS6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_649"/>
    <dbReference type="EnsemblBacteria" id="BAD04734">
        <property type="protein sequence ID" value="BAD04734"/>
        <property type="gene ID" value="PAM_649"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_649"/>
    <dbReference type="HOGENOM" id="CLU_2424063_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="91" mass="10998" checksum="9DC05DAB93CF4B1C" modified="2004-07-05" version="1">MNLNLKNINYTSIFLFIIFLFFIFINYFIKSNLVYAGQVYSEIKKTDSSEQLFDSSETKIEFLRSKIDDLSRKRNSILKEINRIEEHYHFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPU0</accession>
    <name>Q6YPU0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04720">
        <property type="protein sequence ID" value="BAD04720"/>
        <property type="gene ID" value="PAM_635"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_635"/>
    <dbReference type="HOGENOM" id="CLU_3101559_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="51" mass="5544" checksum="2E26295A9C6B9CD1" modified="2004-07-05" version="1">MGPGGRGFKSCLPDHSLINYLCGRRIMAITLAFQAKDVGSIPIARSIYYSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="112" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPV5</accession>
    <name>Q6YPV5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">glnS</name>
        <name evidence="12" type="ordered locus">PAM_620</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="2"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_620"/>
    <dbReference type="EnsemblBacteria" id="BAD04705">
        <property type="protein sequence ID" value="BAD04705"/>
        <property type="gene ID" value="PAM_620"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_620"/>
    <dbReference type="eggNOG" id="COG0008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001882_2_3_14"/>
    <dbReference type="OMA" id="INNFCAQ"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="10">
        <location>
            <begin position="59"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c_C" evidence="11">
        <location>
            <begin position="416"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="604" mass="70221" checksum="12BEB14C9C693BC8" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-04-04" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPX9</accession>
    <name>SYFA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="1">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="1">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pheS</name>
        <name type="ordered locus">PAM_596</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPX9"/>
    <dbReference type="SMR" id="Q6YPX9"/>
    <dbReference type="STRING" id="262768.PAM_596"/>
    <dbReference type="EnsemblBacteria" id="BAD04681">
        <property type="protein sequence ID" value="BAD04681"/>
        <property type="gene ID" value="PAM_596"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_596"/>
    <dbReference type="eggNOG" id="COG0016">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025086_0_1_14"/>
    <dbReference type="OMA" id="DWHNFTA"/>
    <dbReference type="OrthoDB" id="469058at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-721-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000232003" description="Phenylalanine--tRNA ligase alpha subunit">
        <location>
            <begin position="1"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>shared with beta subunit</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <sequence length="344" mass="39732" checksum="514EAE031CE915DF" modified="2004-07-05" version="1">MQTKIKNLTTQFHTSLQKNKHDLDQLMTLDKEFLGKKGILFELTQELKSLPHAQKAVAGKLINVLKQEIILTLQKEKEILQRNQLNAKLLQEEIDPTLPGLKFFQGSAHPLNQIIEQIEDLFLSLGYEIKEGNEIETDFYNFEMLNMGKGHPARAMQDSFYIDPQKLLRTHTSNVQVKEMKARQGGPLKIISPGKVYRKDDDDATHSHQFMQLEGLVIDKNINFSHLKETLLLITKELFGTSQEIHLRPSYFPFTEPSIEVDLVITKKDGTKEYLEILGAGLVHPQVLKNANYDPEKYQGFAFGIGIERIAMIKYQIDNIRHFYTNDIRFLKQFARNTTNNENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPY3</accession>
    <name>Q6YPY3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_592</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_592"/>
    <dbReference type="EnsemblBacteria" id="BAD04677">
        <property type="protein sequence ID" value="BAD04677"/>
        <property type="gene ID" value="PAM_592"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_592"/>
    <dbReference type="eggNOG" id="ENOG5031QSR">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1376944_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="198" mass="23705" checksum="53CF14A1067A4E8E" modified="2004-07-05" version="1">MMKFLWNSNRKCNNILKHLQDIHTIFDKLQQDQKITDIEIMMLLTYDQSVTFVKQKYGLVSGSYFMDASFTQTNPNIKKTSEGLEIHHIKEYQARGLSNPKYAKHHPFEYQKGINLVYCNLLEHFLLHLKICDYSKNPLHPEVGKKGAEIIFHRLAKIFFDNPFEYQKNKRISAQKIYYQKSDFWKCFYLYQSLKVYL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="115" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPY6</accession>
    <name>SYK_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="1">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lysS</name>
        <name type="synonym">pam589</name>
        <name type="ordered locus">PAM_589</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPY6"/>
    <dbReference type="SMR" id="Q6YPY6"/>
    <dbReference type="STRING" id="262768.PAM_589"/>
    <dbReference type="EnsemblBacteria" id="BAD04674">
        <property type="protein sequence ID" value="BAD04674"/>
        <property type="gene ID" value="PAM_589"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_589"/>
    <dbReference type="eggNOG" id="COG1190">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008255_6_0_14"/>
    <dbReference type="OMA" id="EIFGEKC"/>
    <dbReference type="OrthoDB" id="63621at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-714-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000199246" description="Lysine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <sequence length="511" mass="58722" checksum="E8662630D1139521" modified="2004-07-05" version="1">MATKLSEQEIIRHQKMNELKKINIDPFGKKFVPSHSIEQILLQYQKADSLALEQSQIHVCVAGRIVLKRGQGKAGFLHLQDFNFRMQAYIKLDLVGKDAFQIYQNCDLGDIIGIKGFLFKTKTQELTIKALEFIHLTKALKPLPDKFHGLQNREEMRKNRYVDLIVNEKTRQVFLTRSLIMKYIRNFFDNQGFLEVETPILQPTLGGASAKPFITHHNALNCDFYLRIATELPLKKLIVGGMNKVYEIGRLFRNEGIDATHNPEFSTIEAYLAYADMQDIMDLTKQCLQELAQKLFGKLQFTYQNQEIDFSHFAKVSMVASIKEKTGIDFTDNFTLEQCLSLAKKHQIEVMPHFSQGHIIEAFFGKYVENTLIQPTFVYGHPLEISPLAKQNEADPRFTDRFELFIVGKEFANAFSELNDPIEQEKRFLNQLQQKQLGNDEANDMDYDFLNALNYGMPPTGGLGMGLDRLVMLLTDTANIRDVILFPHCKNQNKFSQNKTANKVLTNNDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPZ2</accession>
    <name>Q6YPZ2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized BCR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">degV</name>
        <name evidence="2" type="ordered locus">PAM_583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_583"/>
    <dbReference type="EnsemblBacteria" id="BAD04668">
        <property type="protein sequence ID" value="BAD04668"/>
        <property type="gene ID" value="PAM_583"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_583"/>
    <dbReference type="eggNOG" id="COG1307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048251_4_3_14"/>
    <dbReference type="OMA" id="TELYFTI"/>
    <dbReference type="OrthoDB" id="1288126at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-706-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="288" mass="32452" checksum="9E8F33A45C191678" modified="2004-07-05" version="1">MNKRKLGIVVDSTCGNTYGKNFFEDISVVPLTLIVGETSYMDGAIDNTTLLNFIENKQKVTTSQPNPELFIKAFKEQFDLGYKHVICLTLSSKLSGTHNSALLAKKMLNNPNITVIDTQNIGPGVYFFLQRINDWLTQNPDVCPQTITDKINEEKLKGFLLCTVNNLKILAYNGRISKFRFLIGNLLKIHPILKFQQGVLSIEKKVRNLKNCFNYCLKKILEHKTANNKLDIQVIYVDDDKDAKELLAQITKLANPQIKATLYGAISPVVAAHIGYKGFGFYLNEITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPZ4</accession>
    <name>Q6YPZ4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydropteroate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">folP</name>
        <name evidence="2" type="ordered locus">PAM_581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_581"/>
    <dbReference type="EnsemblBacteria" id="BAD04666">
        <property type="protein sequence ID" value="BAD04666"/>
        <property type="gene ID" value="PAM_581"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_581"/>
    <dbReference type="eggNOG" id="COG0294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008023_0_2_14"/>
    <dbReference type="OMA" id="FSIDTYH"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-704-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pterin-binding" evidence="1">
        <location>
            <begin position="33"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="293" mass="32758" checksum="B204AF73E0AF6B87" modified="2004-07-05" version="1">MMGLNNQTINLYSKHPKIWKLAHNRQIEISHKALIMAIINVTPDSFSDGNQHFTTQKAVNHALRCLKEGVDIIDIGGESTRPGAIPITPLEEQKRILPVIKELSRHPKAIISVDTYHFQTAKLAIKAGAHIINDVCGLQQNPQMAQTIASLNAGVCIMHTGRNRKKLSNALQDQFYFLNHSLEIAKQAQIATEAIVIDPGFGFEKNIDENFDIIKEFEQLTKMELPILVGLSRKRFLKAIIPTESLLQVESLDAITATANFLLRTKGASIFRVHNVKMNKNSLLLADTLMKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPZ7</accession>
    <name>Q6YPZ7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">PAM_578</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_578"/>
    <dbReference type="EnsemblBacteria" id="BAD04663">
        <property type="protein sequence ID" value="BAD04663"/>
        <property type="gene ID" value="PAM_578"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_578"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_9_4_14"/>
    <dbReference type="OrthoDB" id="190468at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-700-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AAA_lid_3" evidence="4">
        <location>
            <begin position="23"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M41" evidence="3">
        <location>
            <begin position="83"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="276" mass="31000" checksum="5A8B5721390F2B1E" modified="2004-07-05" version="1">MPDLEAREAILKIHTKKKKIATDVDLLQITKRTPGMSGAELAAIVNEATILATKNKQESITMKDLEESIDKVSMGPAKKSHKTEEKEKIMTAYHEAGHAVIVMKHPHSESKVRTIIITPRGGALGYVWHTSDKEYFSQTEDKLKYAIVCSLGGAAAEELFCKSRTNRVYSDLKSVTRIAFGMVAYSGMSPLGYINFEHCSEQTRYQVDQEVKKIVDECYKTSKELLITNKTLVEKITKALLEKDNLNQKEVYALDEKNQTPTKSKAKSKPKRTTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ10</accession>
    <name>Q6YQ10_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3 8">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dam</name>
        <name evidence="9" type="ordered locus">PAM_565</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3 8"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_565"/>
    <dbReference type="REBASE" id="7524">
        <property type="entry name" value="M.PhsOYORF565P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04650">
        <property type="protein sequence ID" value="BAD04650"/>
        <property type="gene ID" value="PAM_565"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_565"/>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063430_5_0_14"/>
    <dbReference type="OMA" id="YNKIAYE"/>
    <dbReference type="OrthoDB" id="1206955at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-679-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023095">
        <property type="entry name" value="Ade_MeTrfase_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012263">
        <property type="entry name" value="M_m6A_EcoRV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000398">
        <property type="entry name" value="M_m6A_EcoRV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00571">
        <property type="entry name" value="dam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000398-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="294" mass="35054" checksum="E26EE1D340A19B0F" modified="2004-07-05" version="1">MSFYFIYGLRNTKMQKFINWVGCKKKLLPHLLPLIPKKFKTYYEPFLGSGALYLSLMPKKAILNDNDTQLIQIWKSILYNSQDFYNKALAFENFIYQYPKSQQKQQKEAFKTLLNQYNHLLTKKKKRLTKASLFFILSKYCFHGILRYKDNTSLYTNFGYKSKYKTSLLNLNDLFSLQKHFQKNKHVLLCIDYQKIIAVTKKDDFLFIDPPYYNGKNITISSFYKGVFGFTEQVKLFNCLEKADKRGVKWLYTNYDTPEIRALFKNYYFKSIKSSTTHNLTNKNNNHEIIITNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ16</accession>
    <name>Q6YQ16_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">uvrD</name>
        <name evidence="8" type="ordered locus">PAM_559</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_559"/>
    <dbReference type="EnsemblBacteria" id="BAD04644">
        <property type="protein sequence ID" value="BAD04644"/>
        <property type="gene ID" value="PAM_559"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_559"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011020_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="3"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="846" mass="101357" checksum="698C4BC5D31285E1" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ18</accession>
    <name>Q6YQ18_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_557"/>
    <dbReference type="EnsemblBacteria" id="BAD04642">
        <property type="protein sequence ID" value="BAD04642"/>
        <property type="gene ID" value="PAM_557"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_557"/>
    <dbReference type="HOGENOM" id="CLU_1232954_0_0_14"/>
    <dbReference type="OrthoDB" id="2116149at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-669-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="224" mass="26631" checksum="20BD4B820D639A36" modified="2004-07-05" version="1">MWNLLMILKMIFSFNFLKYLISFDFKDFFYLLYSIFYSIFFTKSSFLFGFNVGWNINFINIYNVIKTIFIFMWEQLTTLIYPLKLFSSLFDFLMQILKIFIDVFGSIIGYIKSSITSLTGQKLMDPSESMWEKIKEIAKLIFSVAVGGSVIYFLKEINNFLLNSFIKIGDLLFKIVLRILDIISIVLKFFLFLFKKVIIILSFILSFLINFLYLWVFENAKKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ19</accession>
    <name>Q6YQ19_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_556"/>
    <dbReference type="EnsemblBacteria" id="BAD04641">
        <property type="protein sequence ID" value="BAD04641"/>
        <property type="gene ID" value="PAM_556"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_556"/>
    <dbReference type="HOGENOM" id="CLU_1843094_0_0_14"/>
    <dbReference type="OrthoDB" id="2051611at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-668-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="156" mass="18434" checksum="3DB7CC4B5998D67B" modified="2004-07-05" version="1">MMDIQQTIINIVESKVFISFTSFIFGIFIYWLYFYIKELKSKYDFSDELRDIVNHYLKKGKISISEYGALVRLMAHMGNYLGIYRKHVETMIKEFGEHGGLNFSEGIFDEKDNNQENKENNNLDEILKENLKLKKQLNNIKNPLIVESIDDTENDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ29</accession>
    <name>Q6YQ29_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_546"/>
    <dbReference type="EnsemblBacteria" id="BAD04631">
        <property type="protein sequence ID" value="BAD04631"/>
        <property type="gene ID" value="PAM_546"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_546"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1935901_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="158" mass="18826" checksum="9E0D6376AAB4268F" modified="2004-07-05" version="1">MNYQEKIKHIQTHFPMSVLLKKLNIIPPNFNINHRFPCPIHQGKNPTCCHFTSDNKIHCWKCCKDYDIIDVYMAIRQIKSFHEAIQKIAGFMNSFEFKALNKQEKEITKITINPLKQLYQPMKSKQSVDEKEINIKKNNYLKRSHLYSTQLEIIIIIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ42</accession>
    <name>Q6YQ42_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04618">
        <property type="protein sequence ID" value="BAD04618"/>
        <property type="gene ID" value="PAM_533"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_533"/>
    <dbReference type="HOGENOM" id="CLU_2001523_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="124" mass="14675" checksum="C5825F39F428A2ED" modified="2004-07-05" version="1">MFIFTILTTITNYFLNYTKGFTTTEILERRTDAIQTTLFAILIVTGFKPVFKLIKNIIIFIKETILGLFFPNKKLQNLEIKNAKQEYREQQLIKKLDEIRDSQNKLQSQISTQNLKVAIWRDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ54</accession>
    <name>Q6YQ54_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">tmk</name>
        <name evidence="5" type="ordered locus">PAM_521</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_521"/>
    <dbReference type="EnsemblBacteria" id="BAD04606">
        <property type="protein sequence ID" value="BAD04606"/>
        <property type="gene ID" value="PAM_521"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_521"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049131_0_2_14"/>
    <dbReference type="OMA" id="FNINHET"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-625-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="4">
        <location>
            <begin position="7"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="204" mass="24015" checksum="300BAE482D7BCF41" modified="2004-07-05" version="1">MMKLIVFEGIDGSGKTSLIHALQPLLKTPHQLYQGLGSSSLGKEIRDLFLNFQQVDYLTRFYLSLANMAQIQVELFKNKQLIILDRWLPSTYAYQLFPFFKEKKLTNLPLKQIFNINHETILKKPDLLIYLEIDPQIGKTRKKKQKSHQRDLIERKSLTYFQTVCQGYKHYLTHYTRDIKQLILNGTDHIPSNIQKIMKYLGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ61</accession>
    <name>Q6YQ61_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">PAM_514</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_514"/>
    <dbReference type="EnsemblBacteria" id="BAD04599">
        <property type="protein sequence ID" value="BAD04599"/>
        <property type="gene ID" value="PAM_514"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_514"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="282"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="596" mass="69713" checksum="43ADDA32D6C9D3E2" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ64</accession>
    <name>Q6YQ64_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase specialized sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fliA</name>
        <name evidence="2" type="ordered locus">PAM_511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_511"/>
    <dbReference type="EnsemblBacteria" id="BAD04596">
        <property type="protein sequence ID" value="BAD04596"/>
        <property type="gene ID" value="PAM_511"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_511"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110732_0_0_14"/>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-613-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="201" mass="23876" checksum="7A3A9CEA24D0D929" modified="2004-07-05" version="1">MLREELFKDFLKNKKNLEIRNQLIDLHLPLVNKLVKQFKYYPRVLQKEDLYQEGVLGLIKALNHYQDLGYDFIAYATPTIKSEIREIIRKSHSPSIPQKNHKKDNLSFQEDFCEPYQINKLNPHQLWLKQVNHEIFLKKMKAKLSETEFKIIHLSFGVPLGNINEDYQICYTNAEIAEKLNLSLKQIENIKNIAIKKLKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ68</accession>
    <name>Q6YQ68_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_507"/>
    <dbReference type="EnsemblBacteria" id="BAD04592">
        <property type="protein sequence ID" value="BAD04592"/>
        <property type="gene ID" value="PAM_507"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_507"/>
    <dbReference type="HOGENOM" id="CLU_065991_1_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="163" mass="19689" checksum="BC755E18A0657C7C" modified="2004-07-05" version="1">MSSFRIGNKHYKIIPFLITTGTLLFFVFWIGGISYKYHLETEERRKLQEVDIKVKARELNNDLYNENKKLKKENEYMKDTPYEFLRYNGEKEYYNLFNHKLVKKIDNDNNIFEYDKNNGLLLKKTDRYNNVEEYGFHGKLIKKTLSDGVWMEYNPVNAKMNET</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ96</accession>
    <name>Q6YQ96_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_479"/>
    <dbReference type="EnsemblBacteria" id="BAD04564">
        <property type="protein sequence ID" value="BAD04564"/>
        <property type="gene ID" value="PAM_479"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_479"/>
    <dbReference type="HOGENOM" id="CLU_969231_0_0_14"/>
    <dbReference type="OrthoDB" id="2145277at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-564-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="287" mass="34238" checksum="FB6D2FD2D0563738" modified="2004-07-05" version="1">MDNYLIAKKTITKNTNYIIFYKYWLFLFLFALIFLKISISCYVFSDEVPNPLNPSNPPTPQNQPTPQNLEQPPQRQLPNPNETPKPNEASQPTTNQPNEQQELPYKPEPAQENEVFKRHKQAKKQQDKQRETCEKETRQQYEKLYDYFYDKDTFTKYWNQRNQRQTKPNPIFEKILSLSGANQASDLESALNQYFNYLIAVLTTKYVLEEYNIQKNSNSQELTSQTEKFSLRDEDDLKRTQLSSFQTDYSNLQFRIEFLNLCNTTHYRARVVDGPGWYQFYCRKVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ98</accession>
    <name>Q6YQ98_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M41 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_477"/>
    <dbReference type="EnsemblBacteria" id="BAD04562">
        <property type="protein sequence ID" value="BAD04562"/>
        <property type="gene ID" value="PAM_477"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_477"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1259288_0_0_14"/>
    <dbReference type="OMA" id="FIHANIK"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M41" evidence="2">
        <location>
            <begin position="51"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="190" mass="22163" checksum="A3E28FE669970DD7" modified="2004-07-05" version="1">MSNQLIHIWLWGLIVINVLFITVIYLGNHTKIKNFLKYDLWGYFLKEKQLEEEEITSYHEAGHTLIALLYPENFQVHYVTIKRTQRTLGHTSCKVLKSDPKTETLLNFGGTAAENILAKNHQMKRLQVGKGSGSDHNSAKHNLNKFSPYPQKDFNAFLQKTEHLLQNNKDALDEIARKLLIKKLYLKRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ99</accession>
    <name>Q6YQ99_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MutT/nudix family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mutT</name>
        <name evidence="3" type="ordered locus">PAM_476</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_476"/>
    <dbReference type="EnsemblBacteria" id="BAD04561">
        <property type="protein sequence ID" value="BAD04561"/>
        <property type="gene ID" value="PAM_476"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_476"/>
    <dbReference type="eggNOG" id="COG1051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_7_0_14"/>
    <dbReference type="OMA" id="GEQPAAC"/>
    <dbReference type="OrthoDB" id="1308416at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-560-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="169" mass="19442" checksum="BEB3F4B40C7644A5" modified="2004-07-05" version="1">MSNYINKLRQKIGKDPLFSPGASVIVYENNKYLLQFRKDFNVWGLHGGAMELGETGADVCVRELEEETGLKALEIHPFRTYCGKHFVINYPNGDVVYPVVMAFVVTKTQGKLSPQDDEVAELKWFDEASLPMDAMMEIDKTFLKDFLQHKNQTQPQTYKTKFCQTKYLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQA2</accession>
    <name>Q6YQA2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">prfB</name>
        <name evidence="7" type="ordered locus">PAM_473</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_473"/>
    <dbReference type="EnsemblBacteria" id="BAD04558">
        <property type="protein sequence ID" value="BAD04558"/>
        <property type="gene ID" value="PAM_473"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_473"/>
    <dbReference type="eggNOG" id="COG1186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036856_6_0_14"/>
    <dbReference type="OMA" id="YVFHPYQ"/>
    <dbReference type="OrthoDB" id="928964at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-558-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004374">
        <property type="entry name" value="PrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00020">
        <property type="entry name" value="prfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0488">Methylation</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="6">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="4">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="369" mass="42601" checksum="86075669BCF99F80" modified="2004-07-05" version="1">MEKYEINQILQNLHQNLQDLKQALDIKKTNQTIEKLNYAMQKEDFWKYPQKAVTISQQFNDLQDKKTTLETLKQNYLDLETLFNLNESPNKTSALLEEELKNLTKAVFDFKIKIFLNQSYDINNAILLFHPGAGGTESQDWCEMLFRMYQKYAQKKNFKTEILDYQPGEGAGIKSATLLIKGTYAYGYLKAEKGVHRLVRISPFDANSKRHTSFVACDVLPEINEEIKINLKTEDLKIDVFRSSGAGGQHVNTTDSAVRITHLPTGLVVGCQNERSQIKNKEKALQMLKTKLFQLASKKQKEENAKKFQSDQKENGWGSQIRSYVFHPYKMVKDHRTNQEIFQLEQVMDGNIDEFINGYLTKIPISSPH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-05-10" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQA4</accession>
    <name>TRMD_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmD</name>
        <name type="ordered locus">PAM_471</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQA4"/>
    <dbReference type="SMR" id="Q6YQA4"/>
    <dbReference type="STRING" id="262768.PAM_471"/>
    <dbReference type="PRIDE" id="Q6YQA4"/>
    <dbReference type="EnsemblBacteria" id="BAD04556">
        <property type="protein sequence ID" value="BAD04556"/>
        <property type="gene ID" value="PAM_471"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_471"/>
    <dbReference type="eggNOG" id="COG0336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047363_0_1_14"/>
    <dbReference type="OMA" id="ILCGHYK"/>
    <dbReference type="OrthoDB" id="525632at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-556-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000060425" description="tRNA (guanine-N(1)-)-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="130"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <sequence length="242" mass="27637" checksum="7BDA8F870C9A1EEB" modified="2004-07-05" version="1">MIIEIITIFPLFFKSFCETSIIKRALEQKKVQIKLHDLRTYSKNKHNQVDDSVYGGGVGMLLSFPPFFDCLQKIKTPQSKVILLSPQGKIFNQIHATNFAQKETHLIILCGNYEGVDARILQYIDAEISIGDYVLTGGEIAATVLVDAITRLLPEVIKEQSFLEDSHQQGLLKHPQYTRPQSYLNHEVPAVLLSGNHAKIRCWRQKESLKATLQKRPDLLENKKLTLEQTKLLTEIKQELQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQB3</accession>
    <name>Q6YQB3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04547">
        <property type="protein sequence ID" value="BAD04547"/>
        <property type="gene ID" value="PAM_462"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_462"/>
    <dbReference type="HOGENOM" id="CLU_2168401_0_0_14"/>
    <dbReference type="OMA" id="QKKEFYE"/>
    <dbReference type="OrthoDB" id="2148213at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-547-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="105" mass="12325" checksum="3C9F831B5A58CF42" modified="2004-07-05" version="1">MDKKQKIKKEFYEHCQCCGSDLGMNINDVYLNLFGVIMALMILISFGFFVLFGFLSLFSFFQINNEIFTTLIYIFVIGSLSFCLIAHFMPKLLFEKLDYEKVEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQB4</accession>
    <name>Q6YQB4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04546">
        <property type="protein sequence ID" value="BAD04546"/>
        <property type="gene ID" value="PAM_461"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_461"/>
    <dbReference type="HOGENOM" id="CLU_2370091_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="95" mass="11392" checksum="86C6B1142558201F" modified="2004-07-05" version="1">MMDIQQTIINIVESKVFISFTSFIFGIFIYWLYLYIKELKSKYDFSDELRDIVNHYLKKGKINISEYGALVRLMANMGNYLGIYRKHVETMIKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="114" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQC2</accession>
    <name>Q6YQC2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Superfamily II DNA and RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">srmB</name>
        <name evidence="3" type="ordered locus">PAM_453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_453"/>
    <dbReference type="EnsemblBacteria" id="BAD04538">
        <property type="protein sequence ID" value="BAD04538"/>
        <property type="gene ID" value="PAM_453"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_453"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_3_14"/>
    <dbReference type="OMA" id="RRFLHDC"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-536-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="25"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="217"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="357" mass="41424" checksum="8FB4DBE677F4FFB1" modified="2004-07-05" version="1">MQNYIQKKILQLQFQTLTPIQKEVFSQFEKPGNLVGIAPTGTGKTHAYLLPILSKIDFQKPFTQAIILVPTNDLVFQVWEMFKQIEKTNFTKILYGGMDKQKAIATFEKKQPPLIIATPDKLLEYAFKLKKINLKYVSYLVLDEADMMFDEVFLTSLDPLINHLKAKILLFSATITEQLKPFINRYFGKSTFIDVYKQSNLNRTFYVLETTTSRMQTLIHLTKVLNPYLALVFVNEKKEQELVFQTLQNDSLKLLNYNSALSVKQRKQSLKAIHKLKYQYVIASDLAARGIDFDASCVIHYNLPSHLEFFFHRSGRTSRMGKKGEIIVLYDPQDIKQKDKINKINSIRNYFSSSLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQD2</accession>
    <name>Q6YQD2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sodA</name>
        <name evidence="9" type="ordered locus">PAM_442</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_442"/>
    <dbReference type="EnsemblBacteria" id="BAD04527">
        <property type="protein sequence ID" value="BAD04527"/>
        <property type="gene ID" value="PAM_442"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_442"/>
    <dbReference type="eggNOG" id="COG0605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031625_0_1_14"/>
    <dbReference type="OMA" id="KWGSFDK"/>
    <dbReference type="OrthoDB" id="1440645at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-522-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="3"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="96"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="202" mass="23405" checksum="B4FF0F221BB150D3" modified="2004-07-05" version="1">MNFTLLSLPYQYDALEPFFDTQTMQLHHLKHHQTYINNLNDALKKHPQLNLSLEQMLTDLSLVPQDIRQTVRNNGGGHFNHSFFWNILKVNNGNTPQGLLKEMIDCEFGSIDSFKDKFANAAKTIFGSGWAWLVLTPQQKLAITFTPNQDVVLNQGTPLLGLDVWEHAYYLSYQNRRVDYIEAFFSVLDWEKVQNNLTQTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQH1</accession>
    <name>Q6YQH1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">himA</name>
        <name evidence="2" type="ordered locus">PAM_402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_402"/>
    <dbReference type="EnsemblBacteria" id="BAD04487">
        <property type="protein sequence ID" value="BAD04487"/>
        <property type="gene ID" value="PAM_402"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_402"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_3_14"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-481-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="96" mass="11052" checksum="EAEB835AB77BAB0D" modified="2004-07-05" version="1">MTKKELIKKIAEVNKTSISKTEEFYNIFEKTLIEAITTNEEVVLSPQIGKFKLKSRKAYIGRNPKTKKKLKIPAKTVVTFKLSKNIKDQVKTLILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-10-07" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQH6</accession>
    <name>Q6YQH6_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sigma70_r2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_397"/>
    <dbReference type="EnsemblBacteria" id="BAD04482">
        <property type="protein sequence ID" value="BAD04482"/>
        <property type="gene ID" value="PAM_397"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_397"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110732_0_0_14"/>
    <dbReference type="OMA" id="CDFIAYA"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="131" mass="15688" checksum="3DA06AB794F2F9BA" modified="2004-07-05" version="1">MLRQELFKDFLKNKQNLEIRNQLIELHLPLVKKLVYQFKYYPRVLTKEDLYQEGILGLIKALNHYQDLGYDFIAYATPTIKSEIRETIRKSHSPSIPKKITKRDNFSFQEEFYEPYQINKLESPSIMVKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQH8</accession>
    <name>Q6YQH8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Site-specific DNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dam</name>
        <name evidence="4" type="ordered locus">PAM_395</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_395"/>
    <dbReference type="REBASE" id="7525">
        <property type="entry name" value="M.PhsOYORF395P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04480">
        <property type="protein sequence ID" value="BAD04480"/>
        <property type="gene ID" value="PAM_395"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_395"/>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063430_5_0_14"/>
    <dbReference type="OMA" id="WRRPFLK"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="219" mass="26501" checksum="30A970507B22A93C" modified="2004-07-05" version="1">MWKRSLQNPHHFVNKVKAIENYIYQYHNQKNQKQAFKHLLNQYNQNAKKRKKLTRSAIFYVLNKYAFRGITCYDKQSNLKTNFGYKPKQKTPIINLNELVTFQRHFQKKKHVLYCTDFRKVIANSQQGDFLFVDPPYYYEGIKDKDFYQKPFSFTDHQQLALELHQTTKRGVKWLYTNYETTPILHLFSNCNIIKTKTTTSHYLTNKKIHQEIIIKNYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQI6</accession>
    <name>Q6YQI6_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Toprim_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">PAM_387</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_387"/>
    <dbReference type="EnsemblBacteria" id="BAD04472">
        <property type="protein sequence ID" value="BAD04472"/>
        <property type="gene ID" value="PAM_387"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_387"/>
    <dbReference type="HOGENOM" id="CLU_952592_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Toprim_N" evidence="4">
        <location>
            <begin position="155"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="292" mass="34961" checksum="E1DB81027526AADF" modified="2004-07-05" version="1">MNYQEKIKHIQTHFPMSVLLKKLKILSLNFNNQHRFPCPIHQGKNPTCCHFTSNNKIHCWKCGKDYDLIDVYMVIRQIKSFSEAIQRIEGFMNSFEFKTLSQQEKETTKITINPLKQLYHSMKPKQPVDEQEINIKKKQLFQKISPLFNQIRDYYHYLLTTNRNNESQPGLTYLTKKRKLTLETIKEFKLGYAPLSDKSLSFRLVNYCKKQNIDTTKLVEYGFIKEKISQQGKKYFHDTFHGSIIIPVENGYNKTFHFYQNHFREVSYFQPKYQALTNFSQTPTLHFSYRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQI8</accession>
    <name>Q6YQI8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_385"/>
    <dbReference type="EnsemblBacteria" id="BAD04470">
        <property type="protein sequence ID" value="BAD04470"/>
        <property type="gene ID" value="PAM_385"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_385"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_21_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_21" evidence="1">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="192" mass="23063" checksum="4096932B1106AAA1" modified="2004-07-05" version="1">MKIKAKLKEKEEKHLLQQKRIKALCLHYQYFYGHRKITDLYQKTFNEFITKKKVYLIMKKNDISCRLRIKKNFTYRNLKNNLQIIPNLINQDFMATKPLQKLFTDITYFKTNQGFLYFSCIIDSFNNQIIASHVSNQQNKDLVLKLLKTAKIKRTLYHSLRSRKVYQSLKINKLYEKGFISMSESYPRDNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQJ2</accession>
    <name>Q6YQJ2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04466">
        <property type="protein sequence ID" value="BAD04466"/>
        <property type="gene ID" value="PAM_381"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_381"/>
    <dbReference type="HOGENOM" id="CLU_175522_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="103" mass="12556" checksum="33118EB1F38D9980" modified="2004-07-05" version="1">MVFYYFRGISFFNYRFYWFYGFNRKKINKLPKEQIPILKETAFENIEEWYDNNNKCTMIKAKYTFDGLNGVCYYQEQLQEKKAVITIFRSLKNASKPKKNPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQK1</accession>
    <name>Q6YQK1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_332</name>
        <name evidence="3" type="ordered locus">PAM_372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_332"/>
    <dbReference type="EnsemblBacteria" id="BAD04417">
        <property type="protein sequence ID" value="BAD04417"/>
        <property type="gene ID" value="PAM_332"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04457">
        <property type="protein sequence ID" value="BAD04457"/>
        <property type="gene ID" value="PAM_372"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_332"/>
    <dbReference type="KEGG" id="poy:PAM_372"/>
    <dbReference type="HOGENOM" id="CLU_2079907_0_0_14"/>
    <dbReference type="OMA" id="INTLMIE"/>
    <dbReference type="OrthoDB" id="2094715at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-394-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-442-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="119" mass="14105" checksum="8E36D3631A0F9E83" modified="2004-07-05" version="1">MIKLQNKFKIISIFLFILLGFFLIFNTKCLHALPGIDLDARKHQLEEEINTLMIELTNVFNDTNLESQTRFNRISLISNRINIVGNNLQMINQQIFARNQYNLQIQINQNQTNNNNRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQK3</accession>
    <name>Q6YQK3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_330</name>
        <name evidence="3" type="ordered locus">PAM_370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_330"/>
    <dbReference type="EnsemblBacteria" id="BAD04415">
        <property type="protein sequence ID" value="BAD04415"/>
        <property type="gene ID" value="PAM_330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04455">
        <property type="protein sequence ID" value="BAD04455"/>
        <property type="gene ID" value="PAM_370"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_330"/>
    <dbReference type="KEGG" id="poy:PAM_370"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1065265_0_0_14"/>
    <dbReference type="OrthoDB" id="1844893at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-392-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-440-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="270" mass="31515" checksum="81824CA2B6B4F536" modified="2004-07-05" version="1">MVKLKKHLLSFNIILFISLGLFLIINNVHQVMAMEGLFHEEIQEITDTEIEENEEITNNISKTNIMTKEKFVSLHEIGHAVVAFELNQRSKEYPGLIKLKRIELKHDDEKIDGSTDFSFDRDNLFGHLFALSVYYGGLEAEKTITTTIEEIKNRGQHDEQDIEKTAQYITERGWFLGDLYLSTDSLEIRKDKIKNIAQTKTQEIIQQYKEFLSPLADELLQREIIGIEEFKRLIKELIIQKKPSQKPEQLETNEQSNYNHKKSKCECVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQK4</accession>
    <name>Q6YQK4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_329</name>
        <name evidence="3" type="ordered locus">PAM_369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04414">
        <property type="protein sequence ID" value="BAD04414"/>
        <property type="gene ID" value="PAM_329"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04454">
        <property type="protein sequence ID" value="BAD04454"/>
        <property type="gene ID" value="PAM_369"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_329"/>
    <dbReference type="KEGG" id="poy:PAM_369"/>
    <dbReference type="HOGENOM" id="CLU_175522_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="107" mass="12688" checksum="B2F67E6631C8C53C" modified="2004-07-05" version="1">MFNIKKIIKWFFIILVILLFLIIVFIMLTDPNKLPKEKIPILKETAFENIEEWYDDNEKCTMIKAKYTFDGLNGVGYYQQQLQEKKVVITIFRSLKNASKPKKNLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQK5</accession>
    <name>Q6YQK5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_328</name>
        <name evidence="3" type="ordered locus">PAM_368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04413">
        <property type="protein sequence ID" value="BAD04413"/>
        <property type="gene ID" value="PAM_328"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04453">
        <property type="protein sequence ID" value="BAD04453"/>
        <property type="gene ID" value="PAM_368"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_328"/>
    <dbReference type="KEGG" id="poy:PAM_368"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1883652_0_0_14"/>
    <dbReference type="OMA" id="QIYEEQR"/>
    <dbReference type="OrthoDB" id="2211165at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-389-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-437-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="135" mass="15734" checksum="942255438F5B59E2" modified="2004-07-05" version="1">MKLKKKQIKKKDKLVILTIPDHGSVESTTEPILLQQEQLQQTPSLGEELKETTKNNETQQLTPEEIIKAKNLLEIQLQQEKINSLALETQKANLEHDLTQKQEQLENNQKLSEQEKQELQKEINQQTDKIRSKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQM9</accession>
    <name>Q6YQM9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">tmk</name>
        <name evidence="5" type="ordered locus">PAM_344</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_344"/>
    <dbReference type="EnsemblBacteria" id="BAD04429">
        <property type="protein sequence ID" value="BAD04429"/>
        <property type="gene ID" value="PAM_344"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_344"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049131_0_2_14"/>
    <dbReference type="OMA" id="VSQGYEL"/>
    <dbReference type="OrthoDB" id="1585072at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-409-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="4">
        <location>
            <begin position="6"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="204" mass="23690" checksum="043573F1EE50C880" modified="2004-07-05" version="1">MKLIVFEGLDGSGKTTLIQKIRKQLEKQGHEVITLQGLGSSSIGQPLRDIFLTNAQLKPLTRYLLSFANMQQIQEEEIKPHLETNKIILIDRWLGSNFAYQAYPRNIDKNYQLFNLLNKQFIKPDMTVYLKIKPQLGLERKQNQKDHKLDVIETHPLSYFRQVSQGYELFLEIKNLGHKLILKEMNSKTTLTNQNQIIKQIGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQN7</accession>
    <name>Q6YQN7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_336</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_336"/>
    <dbReference type="EnsemblBacteria" id="BAD04421">
        <property type="protein sequence ID" value="BAD04421"/>
        <property type="gene ID" value="PAM_336"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_336"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1935901_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="158" mass="18792" checksum="48DBB81E8A3E0E2D" modified="2004-07-05" version="1">MNYQEKIKHIQTHFPMSVLLKKLNIIPPNFNINHRFPCPIHQGKNPTCCHLTSDNKIHCWKCCKDYDIIDVYMAIRQIKSFHEAIQKIAGFMNSFEFKALNKQEKEITKITINPLKQLYQPMKSKQSVDEKEINIKKNNYLKRSHLYSTQLEIIIIIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQR3</accession>
    <name>Q6YQR3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04395">
        <property type="protein sequence ID" value="BAD04395"/>
        <property type="gene ID" value="PAM_310"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_310"/>
    <dbReference type="HOGENOM" id="CLU_1702476_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-369-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="154" mass="18224" checksum="069360D5C28614B9" modified="2004-07-05" version="1">MWGPVFNTPDHTLTKWDGDVKFVKTATETPNNLLLLTSRAYDAQNNLLWGHEDTWDAAFYENNNQTKELYFAPESTSEADKKVDYQNESTCHYFYDQEGFDDGDFNRKRHYTLEDDQLKVDWAHKNTYDCEYNKDKLPKRKKYFNAMVPLIGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQR5</accession>
    <name>Q6YQR5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_308"/>
    <dbReference type="TCDB" id="2.A.88.7.1">
        <property type="family name" value="the vitamin uptake transporter (vut) family"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04393">
        <property type="protein sequence ID" value="BAD04393"/>
        <property type="gene ID" value="PAM_308"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_308"/>
    <dbReference type="HOGENOM" id="CLU_1244757_0_0_14"/>
    <dbReference type="OMA" id="YRFFLPY"/>
    <dbReference type="OrthoDB" id="1536709at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-367-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="227" mass="26700" checksum="2144DD0CE332BE90" modified="2004-07-05" version="1">MLNNQKNVLRKIIAISFLLFLAFGLELLSRYTINATIPCNYAFFRIELIFIILIGYLFGPKYGFWASLFYLLIHYVLEFSFMEVLLHHIHENHNHSHDHENEHASKALIFLYRFFLPYIVCSFSGLFYQKNLNHLTKKTPIIITLVLISVVQIISSILFINLLQENFAKKTFLKWFIPSPSYSWSLNLIYSFSSVIVSNTIIGALFYLINLRLKDNMEFLYGFSKEN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-12-06" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQR8</accession>
    <name>SYA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="1">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">alaS</name>
        <name type="ordered locus">PAM_305</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQR8"/>
    <dbReference type="SMR" id="Q6YQR8"/>
    <dbReference type="STRING" id="262768.PAM_305"/>
    <dbReference type="EnsemblBacteria" id="BAD04390">
        <property type="protein sequence ID" value="BAD04390"/>
        <property type="gene ID" value="PAM_305"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_305"/>
    <dbReference type="eggNOG" id="COG0013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_1_1_14"/>
    <dbReference type="OMA" id="YHHTMFE"/>
    <dbReference type="OrthoDB" id="91428at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-364-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000075165" description="Alanine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="534"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="538"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="639"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="643"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <sequence length="864" mass="99723" checksum="E4E05034F6ECC716" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-01-15" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQU8</accession>
    <name>MIAA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="1">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="1">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="1">IPP transferase</shortName>
            <shortName evidence="1">IPPT</shortName>
            <shortName evidence="1">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">miaA</name>
        <name type="ordered locus">PAM_275</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IPP transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQU8"/>
    <dbReference type="SMR" id="Q6YQU8"/>
    <dbReference type="STRING" id="262768.PAM_275"/>
    <dbReference type="EnsemblBacteria" id="BAD04360">
        <property type="protein sequence ID" value="BAD04360"/>
        <property type="gene ID" value="PAM_275"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_275"/>
    <dbReference type="eggNOG" id="COG0324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032616_0_1_14"/>
    <dbReference type="OMA" id="YAKRQYT"/>
    <dbReference type="OrthoDB" id="1069591at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-333-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000020630" description="tRNA dimethylallyltransferase">
        <location>
            <begin position="1"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <begin position="34"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <sequence length="291" mass="33429" checksum="D5E7F4262DF577F4" modified="2004-07-05" version="1">MKKVIAITGPTASGKTSLSIKIAKKFNLEIINCDSLQMYQKYDIGTAKITLEEAQGIKHHLLDFLAPGTNYSIYHFQKDARKKIEETPLPLFVGGSGLYLKSALFDYELTPKSLFLPPTSLPAIENMIDFIKQKDPQLIANLDLKNPRRILSAYQDLLEGTLRSQKNKKHNSLYSSLIFYLDIDRQILKKRVILRLEQMLKQGFIEEVNQIQTHFPNPNFNIIGYREIKALLEGKITLDQAKTLIIQKTMQYAKRQKTWFKNQIKPIILDALSPDLEKTTICLINDFLKTD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-11-08" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQV5</accession>
    <name>MNMG_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mnmG</name>
        <name evidence="1" type="synonym">gidA</name>
        <name type="ordered locus">PAM_268</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MnmG family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQV5"/>
    <dbReference type="SMR" id="Q6YQV5"/>
    <dbReference type="STRING" id="262768.PAM_268"/>
    <dbReference type="EnsemblBacteria" id="BAD04353">
        <property type="protein sequence ID" value="BAD04353"/>
        <property type="gene ID" value="PAM_268"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_268"/>
    <dbReference type="eggNOG" id="COG0445">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007831_2_2_14"/>
    <dbReference type="OMA" id="FRPGYAI"/>
    <dbReference type="OrthoDB" id="146811at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-325-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0274">FAD</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000117144" description="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG">
        <location>
            <begin position="1"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="9"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <sequence length="617" mass="68812" checksum="B920BFFEB51F5A0A" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-01-15" modified="2022-08-03" version="116" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQV8</accession>
    <name>EFTU_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor Tu</fullName>
            <shortName evidence="2">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tuf</name>
        <name type="ordered locus">PAM_265</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQV8"/>
    <dbReference type="SMR" id="Q6YQV8"/>
    <dbReference type="STRING" id="262768.PAM_265"/>
    <dbReference type="PRIDE" id="Q6YQV8"/>
    <dbReference type="EnsemblBacteria" id="BAD04350">
        <property type="protein sequence ID" value="BAD04350"/>
        <property type="gene ID" value="PAM_265"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_265"/>
    <dbReference type="eggNOG" id="COG0050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_0_0_14"/>
    <dbReference type="OMA" id="EGDKEWG"/>
    <dbReference type="OrthoDB" id="621774at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-322-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0251">Elongation factor</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000015716" description="Elongation factor Tu">
        <location>
            <begin position="1"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="tr-type G">
        <location>
            <begin position="10"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="1">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="1">
        <location>
            <begin position="60"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="1">
        <location>
            <begin position="81"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="1">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="1">
        <location>
            <begin position="174"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <sequence length="394" mass="43406" checksum="C367FCEC1DF47598" modified="2004-07-05" version="1">MANEKFIRNKPHLNVGTIGHVDHGKTTLTAAITQVLSTRGLAKSRAYDQIDNAPEERERGITIKTSHVEYETEKRHYAHVDCPGHADYVKNMITGAAQMDAAILVVSGADSVMPQTREHILLARQVGVPKIVVFLNKCDLSPDEQILELVEMEVRELLSQYDFPGDDIPVIRGSALKALEGDAHYVAQVNELIETLDTYIEDPVREVDKPFLMPVEDVFTITGRGTVVTGRVERGQVKAGDEVEIVGLKETRKTIVTAVEMFKKDLDFAQAGDNVGALLRGINREDVQRGQVLAKPGSVKPHSKFVAQVYVLTKEEGGRHTAFFSQYRPQFYFRTTDITGVVELQGDVKMVMPGDNAELVVTLNNPIAIEEGTKFSIREGGKTVGAGSVSKLLN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-09-05" modified="2022-08-03" version="111" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQX7</accession>
    <name>SYP_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Proline--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="1">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">proS</name>
        <name type="ordered locus">PAM_246</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQX7"/>
    <dbReference type="SMR" id="Q6YQX7"/>
    <dbReference type="STRING" id="262768.PAM_246"/>
    <dbReference type="EnsemblBacteria" id="BAD04331">
        <property type="protein sequence ID" value="BAD04331"/>
        <property type="gene ID" value="PAM_246"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_246"/>
    <dbReference type="eggNOG" id="COG0441">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001882_4_2_14"/>
    <dbReference type="OMA" id="EVYWVTH"/>
    <dbReference type="OrthoDB" id="665824at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-297-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PTHR43382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="SSF64586"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000249144" description="Proline--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01571"/>
        </source>
    </evidence>
    <sequence length="474" mass="54440" checksum="B82290D4362BE120" modified="2004-07-05" version="1">MKTMKRVKTVTARSSDFGKWYTDVCLKAELIAYSEAKGFIIYLPYGYALWENIQKHLNCTLQKTGHQNVYFPLVFPEKLFHKEKNHIQGFSPEAAMITTTGKKNLSEKLVIRPTSEILFSQYYSKTITSYRDLPKLYNQWCNVVRWEKTTKPFLRGKEFLWQEGHTVHATEQEAMQQTLSILDIYQKLGKNLLALPFVCGKKTETEKFAGALITYSIEALMHDGQALQAGTSHYLGTNFAKSFQIQFQDCDHQKKYVHQTSWGVSTRLIGALIMVHSDDEGLVLPPYVSPMQIVIIPLQPQDDAVKQTSENLFSILQKNYRVHLDLQDKTAGWKFSQYELKGVPLRIEIGKRGLENDEVTIFQRYNFAKQNIKTKDLPSQIPQLFETIHNNMYQKALQHLEQNRKQATTYEEFKTYLKQGGYVAMSISGTDAELQIKQETGATARVILETNLITANCPVTNKKALQTVLFARAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQY9</accession>
    <name>Q6YQY9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">PAM_234</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_234"/>
    <dbReference type="EnsemblBacteria" id="BAD04319">
        <property type="protein sequence ID" value="BAD04319"/>
        <property type="gene ID" value="PAM_234"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_234"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_21_3_14"/>
    <dbReference type="OMA" id="VASECKL"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="31"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="224" mass="24869" checksum="DBCEE33B81A82D08" modified="2004-07-05" version="1">MAGMEEEKQLLQRFIDFLKEPKKYHEAGAKIPKGILLYGPPGTGKTLLVKALAGESDSSFYAFSGTDFLQRIHGDGAKKVRDLFEKTKTHKTSIIFIDEIDSFGIARNDFSQKEKEITTELLNQMDGIKSKDNENNVIVIAATNRVESLDSALLRPGRFDYVVNVLLPDLKARKAILKLCAKGKQIADEDINLEQLAQETQGLSGAQLKAILNEASMLQAEKNK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQZ4</accession>
    <name>RL17_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplQ</name>
        <name type="synonym">pam228</name>
        <name type="ordered locus">PAM_228</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQZ4"/>
    <dbReference type="SMR" id="Q6YQZ4"/>
    <dbReference type="STRING" id="262768.PAM_228"/>
    <dbReference type="EnsemblBacteria" id="BAD04313">
        <property type="protein sequence ID" value="BAD04313"/>
        <property type="gene ID" value="PAM_228"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_228"/>
    <dbReference type="eggNOG" id="COG0203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074407_2_2_14"/>
    <dbReference type="OMA" id="YAVTELF"/>
    <dbReference type="OrthoDB" id="1838961at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-274-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000087182" description="50S ribosomal protein L17">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <sequence length="118" mass="13631" checksum="5373E42E9DEA8B72" modified="2004-07-05" version="1">MPFSKLGRNKSQRRALLRTLMTDLIVQEKIMITESKAKELQKLADKMVTLSKKNTLHTRRQAKRHLFDEKINDDTTVLQKLFKDISSKYLDRQGGYTRVIKTVPRRGDGAPMAIIAFV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQZ6</accession>
    <name>RS11_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsK</name>
        <name type="ordered locus">PAM_226</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQZ6"/>
    <dbReference type="SMR" id="Q6YQZ6"/>
    <dbReference type="STRING" id="262768.PAM_226"/>
    <dbReference type="EnsemblBacteria" id="BAD04311">
        <property type="protein sequence ID" value="BAD04311"/>
        <property type="gene ID" value="PAM_226"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_226"/>
    <dbReference type="eggNOG" id="COG0100">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072439_5_0_14"/>
    <dbReference type="OMA" id="KWGVAHI"/>
    <dbReference type="OrthoDB" id="1713391at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-272-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000123191" description="30S ribosomal protein S11">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <sequence length="128" mass="13422" checksum="5046746EACB2F95A" modified="2004-07-05" version="1">MARKKTTKRKVKKNVPLGIAHIHTTFNNTIVTITDLNGNAVTWSSAGALGFKGSRKSTPFAAQLAAEAVAKAAMEHGMVKVETFITGPGPGREAAIRSLQAAGLEITAIKDVTAVPHNGCRPPKPPRG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR04</accession>
    <name>RL30_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmD</name>
        <name type="ordered locus">PAM_218</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR04"/>
    <dbReference type="SMR" id="Q6YR04"/>
    <dbReference type="STRING" id="262768.PAM_218"/>
    <dbReference type="EnsemblBacteria" id="BAD04303">
        <property type="protein sequence ID" value="BAD04303"/>
        <property type="gene ID" value="PAM_218"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_218"/>
    <dbReference type="eggNOG" id="COG1841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131047_2_0_14"/>
    <dbReference type="OMA" id="GKQNQRD"/>
    <dbReference type="OrthoDB" id="2084745at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-264-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01371_B">
        <property type="entry name" value="Ribosomal_L30_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002211">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000347127" description="50S ribosomal protein L30">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01371"/>
        </source>
    </evidence>
    <sequence length="65" mass="7266" checksum="3E234895CFC6D43D" modified="2004-07-05" version="1">MKLKITLTKSLIACRVNQIKTAHCLGLKKINNQVIKDDTPAIHGMIKTISHLVVVEKVSDTKEQK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-10-11" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR19</accession>
    <name>RS10_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsJ</name>
        <name type="ordered locus">PAM_199</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR19"/>
    <dbReference type="SMR" id="Q6YR19"/>
    <dbReference type="STRING" id="262768.PAM_199"/>
    <dbReference type="EnsemblBacteria" id="BAD04284">
        <property type="protein sequence ID" value="BAD04284"/>
        <property type="gene ID" value="PAM_199"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_199"/>
    <dbReference type="eggNOG" id="COG0051">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122625_1_3_14"/>
    <dbReference type="OMA" id="QFEIRVH"/>
    <dbReference type="OrthoDB" id="2012682at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-245-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000146567" description="30S ribosomal protein S10">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <sequence length="107" mass="12471" checksum="029EC209EE1DD298" modified="2004-07-05" version="1">MNKKEKEIIKIILRAYDHHLIDQSAKKIIDILTKTGANIEGPIPLPTRKEVFTVLRSPFVNKDSREQFERRTHKRLIQIINPNKKTIESLMHISLPPAIDILLKKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR28</accession>
    <name>Q6YR28_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type dipeptide/oligopeptide transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dppB</name>
        <name evidence="7" type="ordered locus">PAM_190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_190"/>
    <dbReference type="EnsemblBacteria" id="BAD04275">
        <property type="protein sequence ID" value="BAD04275"/>
        <property type="gene ID" value="PAM_190"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_190"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_0_0_14"/>
    <dbReference type="OMA" id="FLMVNVM"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-230-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
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        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="96"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="308" mass="34833" checksum="C82CA02F3261C0C7" modified="2004-07-05" version="1">MIKYIFKKSLYTITLFITVIFISFFTMKMIPGDPVDAMFEKGLTPELRKLKEKELGLDKPLKTQFINYFKNIFIGDFGKSYYGTKEPVFNLFTKAFTNTFKLAFLSCFFGSLLGIFLGALSAFYEGSKKSFILDFYSIIIISSPSFIIGILLQLTLGHYLRLFPVADFDTPKHVVLPILTLSLLISGSVFKTTKTSMEECLSQPYIKTAYSKGLSKKNIIFKHALKNALIPVVAHIGLLLSFLIGGSIITENIFEIKGVGVLIKHAFDNRNYPVIQCCIILLALFIAIWNLFLDLVYAWLDPKIKQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="118" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR32</accession>
    <name>Q6YR32_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation transport ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mgtA</name>
        <name evidence="9" type="ordered locus">PAM_186</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_186"/>
    <dbReference type="EnsemblBacteria" id="BAD04271">
        <property type="protein sequence ID" value="BAD04271"/>
        <property type="gene ID" value="PAM_186"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_186"/>
    <dbReference type="eggNOG" id="COG0474">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_3_3_14"/>
    <dbReference type="OMA" id="PLWNNMM"/>
    <dbReference type="OrthoDB" id="178322at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-227-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="269"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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        </location>
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        <location>
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        </location>
    </feature>
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            <begin position="822"/>
            <end position="842"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="881"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="918" mass="102990" checksum="7FA3ED283E2E7B2C" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR41</accession>
    <name>Q6YR41_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04262">
        <property type="protein sequence ID" value="BAD04262"/>
        <property type="gene ID" value="PAM_177"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_177"/>
    <dbReference type="HOGENOM" id="CLU_109695_0_0_14"/>
    <dbReference type="OMA" id="VMSFYVP"/>
    <dbReference type="OrthoDB" id="2221021at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-217-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="157" mass="18494" checksum="9EB10D29009C56F9" modified="2004-07-05" version="1">MRFLPLIVMSFYVPWHLSCLGACLAETIGYFVGYGYEFCYQFELIANLACVLSFGLLPGLLLRHQDNFLKMYLVVVLLSALYQTLYWYVMLKWWWTAEINIFSQDITIQQIATTMVNKGLFIALPLVFVTSFFVVILLKELFKRLQFLADNYEFYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR46</accession>
    <name>Q6YR46_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fructose/tagatose bisphosphate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fba</name>
        <name evidence="4" type="ordered locus">PAM_172</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_172"/>
    <dbReference type="EnsemblBacteria" id="BAD04257">
        <property type="protein sequence ID" value="BAD04257"/>
        <property type="gene ID" value="PAM_172"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_172"/>
    <dbReference type="eggNOG" id="COG0191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040088_0_1_14"/>
    <dbReference type="OMA" id="PRTWGKL"/>
    <dbReference type="OrthoDB" id="827430at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-211-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011289">
        <property type="entry name" value="Fruc_bis_ald_class-2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01859">
        <property type="entry name" value="fruc_bis_ald"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="2">
        <location>
            <begin position="209"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="2">
        <location>
            <begin position="230"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="288" mass="31456" checksum="1F90D2092AC4F21B" modified="2004-07-05" version="1">MLTSDKNVLLKAHQQEYAIAQVNINNLEWTKAALQTAEELKSPVILGVSEGAAKYMGGLKTVVAMVRELDAFYKVSVPVILHLDHGSYEGAKQAMEAGFTSVMFDGSHYDFAQNLSKTKEITEICHQKGLLIEAEVGGIGGEEDGIIGQGEIADPQECKQIADLGVDMLAAGIGNVHGKYPDNWTGLDFSVFAKIRELTNKQTPLVLHGGTGIPEDMIKKAISLGVVKINVNTEFQLVFAQATRQYIEEKKDLTDKGFDPRKLLNPGFLAIKELMRHKLALFGSINKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR49</accession>
    <name>Q6YR49_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cdsA</name>
        <name evidence="9" type="ordered locus">PAM_169</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="7"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_169"/>
    <dbReference type="EnsemblBacteria" id="BAD04254">
        <property type="protein sequence ID" value="BAD04254"/>
        <property type="gene ID" value="PAM_169"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_169"/>
    <dbReference type="eggNOG" id="COG0575">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037294_2_2_14"/>
    <dbReference type="OMA" id="VWHISLM"/>
    <dbReference type="OrthoDB" id="1184911at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-208-MON"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="305" mass="35122" checksum="9E455C4147AF8E36" modified="2004-07-05" version="1">MIKKRIITGATLVLFSFFFYYYAPLEIKFVVFALLAIKAVQEMFFILKHPKDNQKQTFIKFGLVATSTLLFFTVVCLMLYPNICQNQNLIKDAKQLNFLFLNKDTFVSLTKSTPSNLNFFLLLFLPFVLVLIMLVFLPFLQTKDVSKTFLITFYIGFLMACLFSLFFLHWHYLLLFFLAVMLTDSSAFLARFPRFCPFLGTRPLAFHLSPKKTQKGAILGTFGSTITVLMVFLFIDCNSCISFPIYAFLISIISQISDLLASKFKRDYGIKDFGSFLPGHGGFLDRFDSWLLSSFFALILFNLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR54</accession>
    <name>Q6YR54_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_162"/>
    <dbReference type="EnsemblBacteria" id="BAD04247">
        <property type="protein sequence ID" value="BAD04247"/>
        <property type="gene ID" value="PAM_162"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_162"/>
    <dbReference type="eggNOG" id="COG0681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1145386_0_0_14"/>
    <dbReference type="OMA" id="IVYLMIM"/>
    <dbReference type="OrthoDB" id="1500314at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-201-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="257" mass="29411" checksum="D8F76F70F4017B81" modified="2004-07-05" version="1">MFKNKTKTPPQSQKTKSMLLILKKSMIIILDFFLIYLFIASLGNAFFPKYSAKYLGIAAFPVASGSMEPFLHGPKNEDSGQIGDLVFIRGVWDASKLMPVGAVDGKQITKNPTTKPYKVGATHPKNGDVVIFENPNYNNPNVSEQERQAAQKHRFIIHRVVYNDSKNELIGTWGDANDTQHKYEQKIPYHKIVGKYVCKDRYIFPSIKNFFSDLFAYIGSFFAFLFENPLYLFLIIVYLMIMAYFLYSLIKELKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR55</accession>
    <name>Q6YR55_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04246">
        <property type="protein sequence ID" value="BAD04246"/>
        <property type="gene ID" value="PAM_161"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_161"/>
    <dbReference type="HOGENOM" id="CLU_1150931_0_0_14"/>
    <dbReference type="OMA" id="KTEIRIW"/>
    <dbReference type="OrthoDB" id="1211455at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-200-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="117"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="163"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="241" mass="28482" checksum="483E0E2E16BF7A98" modified="2004-07-05" version="1">MKIIKLRTRFATITTTFTLLLLLVLIFKSFDNIDNIISIDNISPTKNKPNHNVDVIQEKIYNMDGNIDHILDYDSKTNKKIKLTAFNGDEKCVWYIIEYDLQTANKMKHTVFENDRNILDIKEYDPHTQKLIKEISFAEDKSNILYMYEYDAKSGNVIKETHHNSKNGKVEYVLEYDPQTQNKIKHTKYFPNGNIDYINKYDPKTEIRIWRAKYKYQSKNDDKEVYNYDPNSGDVIKNNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR72</accession>
    <name>Q6YR72_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">rRNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">spoU</name>
        <name evidence="2" type="ordered locus">PAM_144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_144"/>
    <dbReference type="EnsemblBacteria" id="BAD04229">
        <property type="protein sequence ID" value="BAD04229"/>
        <property type="gene ID" value="PAM_144"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_144"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_3_2_14"/>
    <dbReference type="OMA" id="YHEKTIR"/>
    <dbReference type="OrthoDB" id="1697536at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-176-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="94"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="234" mass="26304" checksum="F8D4450496AD91A8" modified="2004-07-05" version="1">MITSKQNPTFKKLKKLQLKKYRDLYQQFLVYGDHLIEQAQKNNAVVTIFTSNEEKPGTFIAPSLMKELSQTKTVFEQMALCKPTSENNLLSDKILVLDDIQDPANLGALMRSASAFGFNQVFASFHSADFYHEKTIRSSQGALFSLSLKRGNTKSFLEEIKEKNYSIFSAFPQKANITMEDAKKYPKKVLVLGNEGQGISLETEALSDYFVNICTQNVESLNVAVAGSILMYLL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-01-24" modified="2022-08-03" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR80</accession>
    <name>RS15_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsO</name>
        <name type="ordered locus">PAM_136</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR80"/>
    <dbReference type="SMR" id="Q6YR80"/>
    <dbReference type="STRING" id="262768.PAM_136"/>
    <dbReference type="EnsemblBacteria" id="BAD04221">
        <property type="protein sequence ID" value="BAD04221"/>
        <property type="gene ID" value="PAM_136"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_136"/>
    <dbReference type="eggNOG" id="COG0184">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148518_2_0_14"/>
    <dbReference type="OMA" id="FKTHVKD"/>
    <dbReference type="OrthoDB" id="1990141at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-168-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000115495" description="30S ribosomal protein S15">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <sequence length="74" mass="8619" checksum="40D2F72A7CEB769D" modified="2004-07-05" version="1">MALTKEQKQEIIKQNSRFAKDTGSSEVQIAILSAEIKQLSEHLKQHPHDFHSKRGLFMKNSKRRDLVKYLANQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="124" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR86</accession>
    <name>Q6YR86_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">hflB</name>
        <name evidence="12" type="synonym">ftsH</name>
        <name evidence="16" type="ordered locus">PAM_130</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_130"/>
    <dbReference type="EnsemblBacteria" id="BAD04215">
        <property type="protein sequence ID" value="BAD04215"/>
        <property type="gene ID" value="PAM_130"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_130"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_16_2_14"/>
    <dbReference type="OMA" id="YDKQGGG"/>
    <dbReference type="OrthoDB" id="190468at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-162-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 12 16" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="15">
        <location>
            <begin position="204"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="610"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="616"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="434"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="212"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="509"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="BAD04215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="674" mass="75359" checksum="B54714301E86F8A0" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR87</accession>
    <name>TILS_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="1">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tilS</name>
        <name type="ordered locus">PAM_129</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text>The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR87"/>
    <dbReference type="SMR" id="Q6YR87"/>
    <dbReference type="STRING" id="262768.PAM_129"/>
    <dbReference type="EnsemblBacteria" id="BAD04214">
        <property type="protein sequence ID" value="BAD04214"/>
        <property type="gene ID" value="PAM_129"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_129"/>
    <dbReference type="eggNOG" id="COG0037">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018869_0_2_14"/>
    <dbReference type="OMA" id="QQYGMNA"/>
    <dbReference type="OrthoDB" id="666797at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-161-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012796">
        <property type="entry name" value="Lysidine-tRNA-synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11734">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00977">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02433">
        <property type="entry name" value="lysidine_TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000181738" description="tRNA(Ile)-lysidine synthase">
        <location>
            <begin position="1"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="21"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <sequence length="436" mass="50652" checksum="21F2E36D3FA03D8F" modified="2004-07-05" version="1">MKTIKLACSLDANQTYIIAVSGGVDSMALLHCLVAQKIKLQVVHFNHLARPNVWKDKELVQSYCLQNSLCFHYFELNCPQKNFQAQARLLRQQKLMQIATKHQTPFILTAHHLDDLAETILQKITRSSTLLGYSGMQIQTSWQDFIFLKPFLYVPKAKIISYAAFYQIPFLEDYTNQNFTYQRNQIRHQVIPYLKTQTSFLQNIPKYQQTLLQAYNFIRKQTLLFLTKHTNHSCNPPNSFALAPFLNLDLVIQKDIILLLLEQQNITKSFIFIQNIIKGINNPYKPNLSWHLNFEWHLIKDYKHITLMSPAPPLSFALSKPLLCVSTCNLCLACISPSLQSLNYNPQKVSFPLKVRLRQPKDTLKFSFGTKKLKKFLIEKKVPLTQRNNLWLVVDNLDNILFIPHLYINLTLGNQSKIYLAFKNFFTSSNCFSQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR92</accession>
    <name>Q6YR92_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_123"/>
    <dbReference type="EnsemblBacteria" id="BAD04208">
        <property type="protein sequence ID" value="BAD04208"/>
        <property type="gene ID" value="PAM_123"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_123"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1089211_0_0_14"/>
    <dbReference type="OrthoDB" id="1152435at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-155-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="255" mass="28614" checksum="AA91006FB8C730D2" modified="2004-07-05" version="1">MYKNGSIKIELASPPLTVGNPLKNAYSMQNVLNKSKASFVLFPELCLSSYTAGDLFFETTFLEQNFQALDWLLKNNSFEGVYILGMPLALHEVLFNVAVIIQKDKILGITPKKTIPNYKEFSEKRWFQSGKTCESQYIQILGQTVPFGDVLFINSQFDLIFGVEICQDLWTVFSPGDLLSLNGAHLIFNPSASTDHIGKLDLRKNAVLDHSRKQIGGYFYTSSGITESTVDNLFSNHKMAALLGEMVAEKIIYQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR99</accession>
    <name>Q6YR99_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_116"/>
    <dbReference type="EnsemblBacteria" id="BAD04201">
        <property type="protein sequence ID" value="BAD04201"/>
        <property type="gene ID" value="PAM_116"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_116"/>
    <dbReference type="HOGENOM" id="CLU_2047293_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="120" mass="14319" checksum="082CA9A644BDAA62" modified="2004-07-05" version="1">MIDILPDTHLKGLDYMQRAHESWEHHHQPSQTNEIHQTGQNMYHNLNNQLRDPAFNRAWQQENKGQYNYNYNQNSSPYQINYTPTIYQVPNANMQIVIQQETQNNQQPNSQTQNNQQPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRA7</accession>
    <name>Q6YRA7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04193">
        <property type="protein sequence ID" value="BAD04193"/>
        <property type="gene ID" value="PAM_108"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_108"/>
    <dbReference type="HOGENOM" id="CLU_1502034_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-139-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="179" mass="20458" checksum="A2FCB80E71B88D10" modified="2004-07-05" version="1">MYLQLIYPAQIKINKEAMNCGGKVDIKVDFDDFVYIAECKMFDKVLNKEMENIDHACDQLMNYINGQNKEGAIFLFNKNSNFAGQIKTIEKWIKDKHKLEPNNCKGPNPNSWVVPIKHVNGHDFTLYIACYNLSSFVAESKKHEKQKDVGIKTVSSHKEGNIQSNEGIQENLTTNKQGE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-06-07" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRA9</accession>
    <name>RL28_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmB</name>
        <name type="ordered locus">PAM_106</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRA9"/>
    <dbReference type="SMR" id="Q6YRA9"/>
    <dbReference type="STRING" id="262768.PAM_106"/>
    <dbReference type="EnsemblBacteria" id="BAD04191">
        <property type="protein sequence ID" value="BAD04191"/>
        <property type="gene ID" value="PAM_106"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_106"/>
    <dbReference type="eggNOG" id="COG0227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064548_7_1_14"/>
    <dbReference type="OMA" id="QKVRIMV"/>
    <dbReference type="OrthoDB" id="2062238at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-137-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000178521" description="50S ribosomal protein L28">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <sequence length="62" mass="7085" checksum="5559479603290978" modified="2004-07-05" version="1">MSKCYITGKTTLFGNRRSHAMNATKRIWKANLQNVKIVDENGKVQKVKISARALKKLKLQRA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-08-16" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRB0</accession>
    <name>RL31_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmE</name>
        <name type="ordered locus">PAM_105</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRB0"/>
    <dbReference type="STRING" id="262768.PAM_105"/>
    <dbReference type="EnsemblBacteria" id="BAD04190">
        <property type="protein sequence ID" value="BAD04190"/>
        <property type="gene ID" value="PAM_105"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_105"/>
    <dbReference type="eggNOG" id="COG0254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114306_4_3_14"/>
    <dbReference type="OMA" id="WYPDAKV"/>
    <dbReference type="OrthoDB" id="2014569at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-136-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00501">
        <property type="entry name" value="Ribosomal_L31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027491">
        <property type="entry name" value="Ribosomal_L31_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000173139" description="50S ribosomal protein L31">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="93" mass="10291" checksum="D3ACDFF26BE72120" modified="2004-07-05" version="1">MKANIHPQFETVEVSCATCGKQHPIGTTVTSIKIETCSNCHPFYTGAQTFVVKAGPVDKFNKRYGITQDQKVKTVSSNADNQKETTEELIKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRC1</accession>
    <name>Q6YRC1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type Mn/Zn transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">znuB</name>
        <name evidence="8" type="ordered locus">PAM_094</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_094"/>
    <dbReference type="EnsemblBacteria" id="BAD04179">
        <property type="protein sequence ID" value="BAD04179"/>
        <property type="gene ID" value="PAM_094"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_094"/>
    <dbReference type="eggNOG" id="COG1108">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_384429_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="526"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="608"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="719" mass="80374" checksum="6782F7518C43AF63" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRD9</accession>
    <name>Q6YRD9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PBPb domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_076"/>
    <dbReference type="EnsemblBacteria" id="BAD04161">
        <property type="protein sequence ID" value="BAD04161"/>
        <property type="gene ID" value="PAM_076"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_076"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_942814_0_0_14"/>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-104-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="295" mass="33764" checksum="3E463E3F7B1C1F3E" modified="2004-07-05" version="1">MAAACFSIMPERRDKMDFSVVYNVPMNALIVRKDNPDFLEFEAGSKVQDKDLFAHLEKLSDKAAEEGKTKKFNFIAMATNTTDKELFKQGNMKAQLSPKYRDNLINYATGSDNAAPNLQAVRENKERGKEVIYVIDDVIARGNVEGDKDLKYISLQTDNPLLLSSPEGIGIAVHKGDKEMLKAVNNALVKLFDLDVKKKEVEKEEDNGTKTFKVEDKIYDLKKILETLRKLKPRLAPQRTKDQETKFAELKGLNSEMIMKKNNLKFYSKFGLGFLLIIHYKKMHQNKDLKIYLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRE7</accession>
    <name>Q6YRE7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_068"/>
    <dbReference type="EnsemblBacteria" id="BAD04153">
        <property type="protein sequence ID" value="BAD04153"/>
        <property type="gene ID" value="PAM_068"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_068"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1137139_0_0_14"/>
    <dbReference type="OrthoDB" id="1779749at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-90-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="241" mass="28787" checksum="82342134CBF42D88" modified="2004-07-05" version="1">MFNIKKIIKWFFIILGILLFLLIGFFVLTEMEIIKLPKEEIPILKETAFENIEEWYDDKQKCTMIKAKYTFDGLNGIGYYQQQLANKENIGSFELMKIQDLLELQKEPSNLVCYIKDRHPFDRWNKRGLDYKQTSVNEFKYSSCDMEDDSHLYSNINFEKQFKENSSGNCLILKYKGPKHFLDEDKDYYLGCSHVSNSNFKLTHFHLHFNPKRKTLSLYEGKHNNDKAKEAENNKRTREDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRE8</accession>
    <name>Q6YRE8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_067"/>
    <dbReference type="EnsemblBacteria" id="BAD04152">
        <property type="protein sequence ID" value="BAD04152"/>
        <property type="gene ID" value="PAM_067"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_067"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115275_0_0_14"/>
    <dbReference type="OrthoDB" id="1592351at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-89-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="207" mass="24578" checksum="E3469BD7EC505888" modified="2004-07-05" version="1">MTEQLQNQLQEKKSLIETKNQELITNQALSQQEKQALQNEINQLTTNFQQKEKEYQATIYQKDQEITHLNQIINEQANEINRLSEELEQQIDKWVKQGLHIESLEGTIKALENVSSKYFEENAELRHEINKLKEQIKDEQKAHEATKVKLKENSDELTQKTTEYDKIKDTIKNQKTWKGSIQPFTTKIKDDVNKKVENVTSWFKKWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRF3</accession>
    <name>Q6YRF3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_062"/>
    <dbReference type="EnsemblBacteria" id="BAD04147">
        <property type="protein sequence ID" value="BAD04147"/>
        <property type="gene ID" value="PAM_062"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_062"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_197523_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="60" mass="6962" checksum="286B25D2B0716EE2" modified="2004-07-05" version="1">MLNKVQLIGRLSHDLEKQYINSNNEQIPKIDFQLAVTLKEITQFILCGGFRKQADNMKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRH1</accession>
    <name>Q6YRH1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_044"/>
    <dbReference type="EnsemblBacteria" id="BAD04129">
        <property type="protein sequence ID" value="BAD04129"/>
        <property type="gene ID" value="PAM_044"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_044"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1053089_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="176"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="264" mass="31350" checksum="82501F169148AB2D" modified="2004-07-05" version="1">MKNQKQQQLTELKNQQQTQQTLVDNLLEQRRVLNQNQKEKQEELEKLAKEKDQLQTQENLQQQIFQLNQALNYVEANQKRIEELKTQKEYRKNQTELKNFKDFQLFLTDQKLAFEKQKKNLTIQFNHLKENKSLPHTKKQVTFKDVYGMETEKEELEDLLTYFRTNQSLINFDQVRPKGYLLYGPPGTGKTFLIKALCGEANVHFINLIPSKFRQKYIGEGEKEVEKVWQEAESHYKTIIFIDEIEGLENRNDSNISSGRSQCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRH5</accession>
    <name>Q6YRH5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase specialized sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fliA</name>
        <name evidence="2" type="ordered locus">PAM_040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_040"/>
    <dbReference type="EnsemblBacteria" id="BAD04125">
        <property type="protein sequence ID" value="BAD04125"/>
        <property type="gene ID" value="PAM_040"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_040"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110732_0_0_14"/>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-56-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="201" mass="24055" checksum="CA3DF8C63B197D1B" modified="2004-07-05" version="1">MLRQELFKDFLKNKQNLEIRNQLIELHLPLVKKLVYQFKYYPRVLTKKDLYQEGILGLIKALNHYQDLGYDFMAYATPTIKSEIREIIRKSHSPSIPQKNHKTDNLSFREEFYEPYQINKLNPHQLWLKQVKHEKFLKKMKAKLSETKFKIIHLSFGVPLGNINEDYQRCYTNAEIAEKLNLSLKQVENIKNIAIKKLKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRI8</accession>
    <name>Q6YRI8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type dipeptide/oligopeptide transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">oppF</name>
        <name evidence="2" type="ordered locus">PAM_026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_026"/>
    <dbReference type="EnsemblBacteria" id="BAD04111">
        <property type="protein sequence ID" value="BAD04111"/>
        <property type="gene ID" value="PAM_026"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_026"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_14"/>
    <dbReference type="OMA" id="ELIRIWE"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="18"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="153" mass="17606" checksum="06808802911EBB38" modified="2004-07-05" version="1">MIVRDLVEEGLIFQGIKDKNQRKVQVLEMIKLVGLQENDLSRYHHEFSGGQKQRIVIARALIVKPTLIIADEPVSALDVSIQAQILNLLNELKEKLKLTIVFISHDLSIVKYFFDRCAVMYHGNVVEMANVKDIFVFTQHQYTKILLKDDNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRJ2</accession>
    <name>Q6YRJ2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type dipeptide/oligopeptide transport system, permease component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dppB</name>
        <name evidence="6" type="ordered locus">PAM_022</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_022"/>
    <dbReference type="EnsemblBacteria" id="BAD04107">
        <property type="protein sequence ID" value="BAD04107"/>
        <property type="gene ID" value="PAM_022"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_022"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1968303_0_0_14"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-29-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="127" mass="14922" checksum="5796A79BCD35B048" modified="2004-07-05" version="1">MTLGTLVIAIMAQYLFVHVWHLFPYQVATSMEWKEKGFWFGVNSYLLPLAVMTLLSMVFYIRKIRAELIEQTNQNYFLLARSKGLTFSQTINRHALKNSLVPYAPVFFYEFVGLITGSFLIERIFFY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-15" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q7WSH2</accession>
    <accession>Q6YQZ3</accession>
    <name>KTHY_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thymidylate kinase</fullName>
            <ecNumber evidence="1">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tmk</name>
        <name type="synonym">tmk-B</name>
        <name type="ordered locus">PAM_230</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2003" name="Microbiology" volume="149" first="2243" last="2250">
            <title>Two different thymidylate kinase gene homologues, including one that has catalytic activity, are encoded in the onion yellows phytoplasma genome.</title>
            <authorList>
                <person name="Miyata S."/>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Kuboyama T."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="12904564"/>
            <dbReference type="DOI" id="10.1099/mic.0.25834-0"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="1"/>
    <dbReference type="EMBL" id="AB094668">
        <property type="protein sequence ID" value="BAC81721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q7WSH2"/>
    <dbReference type="SMR" id="Q7WSH2"/>
    <dbReference type="STRING" id="262768.PAM_230"/>
    <dbReference type="EnsemblBacteria" id="BAD04315">
        <property type="protein sequence ID" value="BAD04315"/>
        <property type="gene ID" value="PAM_230"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_230"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049131_0_2_14"/>
    <dbReference type="OMA" id="VMTREPG"/>
    <dbReference type="OrthoDB" id="1585072at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-276-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000155315" description="Thymidylate kinase">
        <location>
            <begin position="1"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <sequence length="207" mass="24083" checksum="189AAD655D674ABD" modified="2003-10-01" version="1">MFISFEGCEGTGKTTHSRYLFEKLSKKYSCVLTKEPGGGLFNEVIRNILLHSSNKQIDFHTEALLFAADRAEHLSKLIIPALQQNKIVICDRYLDSTIAYQVYARGLSQDFVLNINNFALNYIPNITFYLDLDPKIGIQRVKQFRPKEINSFDLQKLSFHKKVRKGYLDLCQKDQQKRIFLIDASKPLENIYNIIEQKLKEVFQIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-02-05" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A9JR01</accession>
    <name>A9JR01_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">himA</name>
        <name evidence="2" type="ordered locus">PAM_758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAF95568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_758"/>
    <dbReference type="EnsemblBacteria" id="BAF95568">
        <property type="protein sequence ID" value="BAF95568"/>
        <property type="gene ID" value="PAM_758"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_758"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_3_14"/>
    <dbReference type="OMA" id="FKMSKPI"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-508-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF95568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="110" mass="12454" checksum="B0F96C01C49067AF" modified="2008-02-05" version="1">MNKKELIKSIAEVNKTSITQTEEFYNSFENALIKAITSNEEVVLSSKIGKFILKTRKAHTTPETKFIINKQTGKKTGKRTGKNLKIPAKTVVSFKMSKPIKDEVKKLQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-02-05" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A9JR04</accession>
    <name>A9JR04_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hflB</name>
        <name evidence="4" type="ordered locus">PAM_762</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAF95572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_762"/>
    <dbReference type="EnsemblBacteria" id="BAF95572">
        <property type="protein sequence ID" value="BAF95572"/>
        <property type="gene ID" value="PAM_762"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_762"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1193896_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AAA_lid_3" evidence="3">
        <location>
            <begin position="99"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M41" evidence="2">
        <location>
            <begin position="159"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF95572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="232" mass="26331" checksum="7CD9F2D45D3BF716" modified="2008-02-05" version="1">MRIKNLNQRTKLWYQHRKKYINASEMASITGLDPFRSMEQLVHDKLFDTTFTANQYTILDHALLRPGRFDRKVTVGLPDLETREAILKVQTRKKKLAADVDLLQVAKRTPGMSGAELAAVLNEATILATKNKQESITMQDLEESIDKVYMGPAKKSLKIDDKERKMTAYHEAGHAVIVMKHPHSDAKVRTLTITPRGGALGYMWPTFDKEFFCHTEDQLKYEIVVSLGAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-05" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C0H5W6</accession>
    <name>C0H5W6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tengu-su inducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tengu</name>
        <name evidence="1" type="synonym">TENGU</name>
        <name evidence="1" type="ordered locus">PAM_765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAH29766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAH29766">
        <property type="protein sequence ID" value="BAH29766"/>
        <property type="gene ID" value="PAM_765"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_765"/>
    <dbReference type="HOGENOM" id="CLU_2753939_0_0_14"/>
    <dbReference type="OMA" id="EQIKIQC"/>
    <dbReference type="OrthoDB" id="1970839at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-571-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAH29766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="70" mass="8188" checksum="8760BA6B755BC460" modified="2009-05-05" version="1">MVKLKKHKAKLLIFAGFWAILLFLNHNYLIFADQDDDIENVITLIETKENQTEQIKIQCQDLLQKGEKDA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-02-16" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>P60471</accession>
    <name>SSB_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="1">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">ssb</name>
        <name type="ordered locus">PAM_781</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid">
        <name>EcOYM</name>
    </geneLocation>
    <reference key="1">
        <citation type="journal article" date="2002" name="Microbiology" volume="148" first="1389" last="1396">
            <title>Evidence of intermolecular recombination between extrachromosomal DNAs in phytoplasma: a trigger for the biological diversity of phytoplasma?</title>
            <authorList>
                <person name="Nishigawa H."/>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Jung H.Y."/>
                <person name="Kuboyama T."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="11988512"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <dbReference type="EMBL" id="AB076263">
        <property type="protein sequence ID" value="BAD04085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959590.1">
        <property type="nucleotide sequence ID" value="NC_019167.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959596.1">
        <property type="nucleotide sequence ID" value="NC_019168.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959602.1">
        <property type="nucleotide sequence ID" value="NC_019169.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959606.1">
        <property type="nucleotide sequence ID" value="NC_019170.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959610.1">
        <property type="nucleotide sequence ID" value="NC_019171.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_214984.1">
        <property type="nucleotide sequence ID" value="NC_006903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P60471"/>
    <dbReference type="SMR" id="P60471"/>
    <dbReference type="OMA" id="VFRNQAD"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Plasmid EcOYM"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0614">Plasmid</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000096074" description="Single-stranded DNA-binding protein">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="SSB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <sequence length="104" mass="12052" checksum="8CA1BB5F2BD706D1" modified="2004-02-16" version="1">MLNKVQLIGNITHDLEQQYINTNEGKIPKVNFQLAVNNKDTTQFIPCVVFRNQADNMFMYLHKGSKVYVEGTLSIEKYINNESENKTSTKVIVQRVIFLDNKNQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-04-13" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>P60743</accession>
    <name>RL24_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName>50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">rplX</name>
        <name type="ordered locus">PAM_211</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P60743"/>
    <dbReference type="STRING" id="262768.PAM_211"/>
    <dbReference type="EnsemblBacteria" id="BAD04296">
        <property type="protein sequence ID" value="BAD04296"/>
        <property type="gene ID" value="PAM_211"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_211"/>
    <dbReference type="eggNOG" id="COG0198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093315_4_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000130689" description="50S ribosomal protein L24">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="79" mass="8736" checksum="881680E8FA809FA1" modified="2004-04-13" version="1">MPKLKKLLLKVSTSKPNTNPPSQNEEKGTIVKQEAPIHVSNVALVCPQTQTPTKVGIRIQSGKKVRYAKKSNQTLDEKN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-04-13" modified="2022-08-03" version="114" xmlns="http://uniprot.org/uniprot">
    <accession>P60792</accession>
    <name>LEPA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor 4</fullName>
            <shortName evidence="1">EF-4</shortName>
            <ecNumber evidence="1">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lepA</name>
        <name type="ordered locus">PAM_445</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P60792"/>
    <dbReference type="SMR" id="P60792"/>
    <dbReference type="STRING" id="262768.PAM_445"/>
    <dbReference type="EnsemblBacteria" id="BAD04530">
        <property type="protein sequence ID" value="BAD04530"/>
        <property type="gene ID" value="PAM_445"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_445"/>
    <dbReference type="eggNOG" id="COG0481">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009995_3_3_14"/>
    <dbReference type="OMA" id="MVQIAIQ"/>
    <dbReference type="OrthoDB" id="182107at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-525-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000176313" description="Elongation factor 4">
        <location>
            <begin position="1"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="tr-type G">
        <location>
            <begin position="11"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="23"/>
            <end position="28"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="140"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <sequence length="605" mass="67951" checksum="49EFCBB0847521B8" modified="2004-04-13" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-07-05" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>P62439</accession>
    <name>RL11_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplK</name>
        <name type="ordered locus">PAM_256</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2004" name="Microbiology" volume="150" first="135" last="142">
            <title>Secretion of immunodominant membrane protein from Onion yellows phytoplasma through the Sec protein-translocation system in Escherichia coli.</title>
            <authorList>
                <person name="Kakizawa S."/>
                <person name="Oshima K."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Tanaka M."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14702406"/>
            <dbReference type="DOI" id="10.1099/mic.0.26521-0"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-113</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AB110270">
        <property type="protein sequence ID" value="BAD07007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P62439"/>
    <dbReference type="SMR" id="P62439"/>
    <dbReference type="STRING" id="262768.PAM_256"/>
    <dbReference type="EnsemblBacteria" id="BAD04341">
        <property type="protein sequence ID" value="BAD04341"/>
        <property type="gene ID" value="PAM_256"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_256"/>
    <dbReference type="eggNOG" id="COG0080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074237_2_1_14"/>
    <dbReference type="OMA" id="CKQFNAK"/>
    <dbReference type="OrthoDB" id="1702697at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-313-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000104331" description="50S ribosomal protein L11">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 2; BAD07007." evidence="2" ref="2">
        <original>S</original>
        <variation>A</variation>
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="141" mass="15127" checksum="B5DFBBB033C50B58" modified="2004-07-05" version="1">MAKKVVKTVKLQIPAGKANPAPPVGPALGQAQVNIPSFCSQFNETTKDQMGFVIPVIISVYEDRTFTFVTKTPPASDLLKKAAKIESGSANASQTKVATITHKQVEEIANLKLPDLNAYCVEKACKIIEGTARNMGILVKD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-11-25" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPI5</accession>
    <name>RL20_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplT</name>
        <name type="ordered locus">PAM_742</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPI5"/>
    <dbReference type="SMR" id="Q6YPI5"/>
    <dbReference type="STRING" id="262768.PAM_742"/>
    <dbReference type="PRIDE" id="Q6YPI5"/>
    <dbReference type="EnsemblBacteria" id="BAD04827">
        <property type="protein sequence ID" value="BAD04827"/>
        <property type="gene ID" value="PAM_742"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_742"/>
    <dbReference type="eggNOG" id="COG0292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082429_0_0_14"/>
    <dbReference type="OMA" id="RINAGAM"/>
    <dbReference type="OrthoDB" id="1661719at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-897-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000355476" description="50S ribosomal protein L20">
        <location>
            <begin position="1"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="207" mass="23759" checksum="B5EB1338A0269C0A" modified="2004-07-05" version="1">MAKISFTPARHRRRKKVLKMAKGYFGSKSTLYKTAHEQVMRSLQYAYRDRKQRKRDFRKLWISRINAGAMLCGMQYSYLMHGLALAKVDVNRKVLADLAHLQPGPVESVKAVEVLQQETQPQPEEKTSLQPEKVLSTELSEEKSDDTLETKPQTTQVKAKKPSLDLSKMLLHELKKLAKEHKVPNFHKLKKAEIVTALKKALAKKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPJ0</accession>
    <name>Q6YPJ0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed RNA polymerase subunit omega</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Transcriptase subunit omega</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpoZ</name>
        <name evidence="10" type="ordered locus">PAM_736</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase subunit omega family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_736"/>
    <dbReference type="EnsemblBacteria" id="BAD04821">
        <property type="protein sequence ID" value="BAD04821"/>
        <property type="gene ID" value="PAM_736"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_736"/>
    <dbReference type="eggNOG" id="COG1758">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2845519_0_0_14"/>
    <dbReference type="OMA" id="AHVIEAQ"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003716">
        <property type="entry name" value="DNA-dir_RNA_pol_omega"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
        <property type="entry name" value="SSF63562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00690">
        <property type="entry name" value="rpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="65" mass="7496" checksum="B4F0AF6AC9111A10" modified="2004-07-05" version="1">MVMQNNSKPNKKKYNKEGLIYPSIDKLLDQINSKYKLVHIASKTAHVIEAQKKELPELVCNKVGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPK2</accession>
    <name>Q6YPK2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aamy domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">PAM_723</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_723"/>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04808">
        <property type="protein sequence ID" value="BAD04808"/>
        <property type="gene ID" value="PAM_723"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_723"/>
    <dbReference type="eggNOG" id="COG0366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021358_1_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004645">
        <property type="term" value="F:1,4-alpha-oligoglucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044262">
        <property type="term" value="P:cellular carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016377">
        <property type="entry name" value="Sucrose_GGa_phosphorylase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022527">
        <property type="entry name" value="Sucrose_phospho"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003059">
        <property type="entry name" value="Sucrose_phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03852">
        <property type="entry name" value="sucrose_gtfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="6">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>sucrose</name>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="115"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>sucrose</name>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>sucrose</name>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="214"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>sucrose</name>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="258"/>
            <end position="261"/>
        </location>
        <ligand>
            <name>sucrose</name>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>sucrose</name>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR003059-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR003059-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="403" mass="47020" checksum="0D514B0DC05764F7" modified="2004-07-05" version="1">MFDFMINHLSSKSLMYQDFKKNHNNSQYKDFFLRWEKFWQQVGPNRPTKQDVDSIYKRKDKAPTHLIEFDDGTTEHLWNTFGTDQIDLNVKEPIVKEFIKTTLTNMVKQGASIIRLDAFAYACKKADTSFFVEPDIWQLLDEVRDVLKPLDVELLPEIHENHSISHKISEHGYFIYDFALPLVVLYTLYSKNPQRLVEWLKKSPMKKFTTLDTHDGIGVIDAYDILTDKEIKYTSEQLYKQGANVKKVYSSSLYNNLDIYQINFTYYSALGNDDDAYLLSRAFQIFAPGIPQVYYVCLFAGENDIKLLESSKEGRNTNRHYYSRQEIKEEVKRPVVANLFKLLAWRNKSNAFDLDGVMECSAYASKIKILRKDKLGNNVAVLDADLMNKKFVIVENDKQIFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPL3</accession>
    <name>Q6YPL3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_712"/>
    <dbReference type="EnsemblBacteria" id="BAD04797">
        <property type="protein sequence ID" value="BAD04797"/>
        <property type="gene ID" value="PAM_712"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_712"/>
    <dbReference type="HOGENOM" id="CLU_1413921_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-867-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="192" mass="22603" checksum="E17DD1F4CD07877B" modified="2004-07-05" version="1">MVYISFIINCSCFLSDVVFKSSGTKISHNTIDEYIDEEIQNLKSYKMVQEALTKLKAKKQINFSEKENLLQIIENSDISQEDKKNLQTALDSNISFSVNPQSNALSKANLIILEKITDKNTKKIKNNEISKINFIKKENDFIHSEPIYKIEIIKQNDTYYLITDDRFFNKKKDFLEENKIKIPFEYYKKLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPM3</accession>
    <name>Q6YPM3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase sigma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpoD</name>
        <name evidence="2" type="ordered locus">PAM_702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_702"/>
    <dbReference type="EnsemblBacteria" id="BAD04787">
        <property type="protein sequence ID" value="BAD04787"/>
        <property type="gene ID" value="PAM_702"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_702"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110732_0_0_14"/>
    <dbReference type="OMA" id="NINQGTH"/>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-854-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="208" mass="24679" checksum="02E1035D1DE4E141" modified="2004-07-05" version="1">MLRQNLFKDFLKNKKNLEIRNHLIELHLPLVKKLTYQFKYYPRVLTKEDLYQEGILGLIKALNNYQDLGYDFVTYATPKIKFAINELIRKSHSPSIPQKTTKPNNISFKEEQHKQPNWDKILNPHQLWLKQIKYELLIKKLKTKLSKNEFNVICLSFGISLENNNEPNQQPLTNHAIAQKLNLKLSQIEDLKDNAIRKLNPNYKNKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPN0</accession>
    <name>Q6YPN0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hflB</name>
        <name evidence="4" type="ordered locus">PAM_695</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_695"/>
    <dbReference type="EnsemblBacteria" id="BAD04780">
        <property type="protein sequence ID" value="BAD04780"/>
        <property type="gene ID" value="PAM_695"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_695"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="OMA" id="RWVEQLT"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="109"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="502" mass="59093" checksum="E8F34338F783ACFF" modified="2004-07-05" version="1">MQQSINYNNANKERIKELITQHQDDPQEIQNLKSYDLFLDGQLIQFKKQIKQLKNEIEIIQNPNTPKLEKKKVTFKDVYGMEREKEELEDLIYYFKDDNNDLVNYDKIKPKGYLLYGPPGTGKSFLMKALCNETEAHFIEFEPSKLDKTYIGEGTEEWEKIWKEAESHGKAIIFIDEISGLANREDKNTNKTSQNIINNILTKLDGFNSNNKKIVLMGATNYLNQIDKALRSRFSKEIKIDLIKDHEIEDFLKFLITPYQISYHTYIHLNDIANKCKGKNYSNRDLTTIINEAYNKTNKYKSQNKIHEVMLPSDLDEAIDVKQNKNKNMNDIKKRRKECEEQYTAWKKGIIKYLKPPKDQTMIKRTYTFYGLNGLGRGHHREHEPADLALFVKNPFDKWYDEGMRVDEFDGFHTKYKDKNSQFDGGNGVSINPLNHTIYINYKGPKHLLEEDKDFFMDEVNCTSNERSPEGVLKSKTYYLHFNPKQAYITLYTQKHNTKENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPN9</accession>
    <name>Q6YPN9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replicative DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dnaB</name>
        <name evidence="2" type="ordered locus">PAM_686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_686"/>
    <dbReference type="EnsemblBacteria" id="BAD04771">
        <property type="protein sequence ID" value="BAD04771"/>
        <property type="gene ID" value="PAM_686"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_686"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_546093_0_0_14"/>
    <dbReference type="OMA" id="NQNNTHV"/>
    <dbReference type="OrthoDB" id="472584at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-837-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="1">
        <location>
            <begin position="192"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="499" mass="58805" checksum="EA5E7E93D3851463" modified="2004-07-05" version="1">MNQLTNEQRALQQLITYIEQGQWEKLNLYCQIINPKTLLTPQNTKIFSAFKYLFLEKQTTHPFDKITTKSVIIQELLTYLQANFPKDKFTLESLNYLNDDFNNQNNTHVLDNLKHTYTQEKLFQKLIKIISPTYENQDPYHKNLYYQEIFDKLRIFISSIPHKSDQTLFNLNQMAFLHPEFFDTDNQAKQKIQEEYYRLSETFKGINQATKGFKKGQIITIGGYTGLGKTTFVYNLLLDIAKTKHQENSCYPHMLVFSYEMTLEENLSRLLAHLTKTPLDVILDKNFEDSNITQHIYTERMKTAKHFFANINLSFSYDKSKNIDYVIDLVYRLHLEKKAEIIVIDHLQITKTTNHLENDRLAIDEIMTKLKQLAIELNIFIIILSQFSRDTYNNYQGKSPEITALKGSGGIETNSDIVLMMTEFQHPTIQRQRKPINIYNSTLNQLYLESKDNENQKIIEICIKKNRSGTKKTLIYHFELTTQTFQEIGYILPYQIETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPP2</accession>
    <name>Q6YPP2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tra5</name>
        <name evidence="2" type="ordered locus">PAM_683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_683"/>
    <dbReference type="EnsemblBacteria" id="BAD04768">
        <property type="protein sequence ID" value="BAD04768"/>
        <property type="gene ID" value="PAM_683"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_683"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_4_3_14"/>
    <dbReference type="OMA" id="DEVKCRI"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="152"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="315" mass="37612" checksum="B9B17ABF21B1BC8E" modified="2004-07-05" version="1">MMRNTNNKKEIELLQTVIDYSDPNLENIIFTLVKFYQKYFFIYKILKLLKINRNTYYSWQRNKKQKEKTKITNSLIIERIGILCQKNYFSFGYRKITVLYQRVFKTNINHKLVLKIMKKNKWLMKWKQPNSKNKFYEEFSKKQPNLIKNNFKTNKPLTKLYTDLTCFANIKGHLWVSTIIDGYNNQVLASVISKNPNLELVKKTFKKIPKLKEPCIIHSDQGKVYQSIKFQSYLNNRGFLISMSRKATPNDNAVIESYYSNLKGFMKTQEPRLFLDSFDMINKKVKKFISFYNKNWLFAKLGYQSPLGYLKSLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPP4</accession>
    <name>Q6YPP4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_681"/>
    <dbReference type="EnsemblBacteria" id="BAD04766">
        <property type="protein sequence ID" value="BAD04766"/>
        <property type="gene ID" value="PAM_681"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_681"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_41_5_14"/>
    <dbReference type="OMA" id="YFAKFWN"/>
    <dbReference type="OrthoDB" id="1637053at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-831-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13333">
        <property type="entry name" value="rve_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="14"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="72" mass="8650" checksum="1A5E177BAE6CF80E" modified="2004-07-05" version="1">MSRKATPRDNAVIENFFGQMKTILQHQHPFLFQKSTEKVKKIINYFLKFWNNQWILAKLNYSSPSQYSQNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="111" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPP6</accession>
    <name>Q6YPP6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Signal recognition particle-docking protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ftsY</name>
        <name evidence="9" type="ordered locus">PAM_679</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_679"/>
    <dbReference type="EnsemblBacteria" id="BAD04764">
        <property type="protein sequence ID" value="BAD04764"/>
        <property type="gene ID" value="PAM_679"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_679"/>
    <dbReference type="eggNOG" id="COG0552">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009301_2_0_14"/>
    <dbReference type="OMA" id="GISDQFQ"/>
    <dbReference type="OrthoDB" id="656414at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-829-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54_N" evidence="8">
        <location>
            <begin position="18"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="136"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54" evidence="7">
        <location>
            <begin position="137"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="347" mass="39024" checksum="F4F15084A1049FE7" modified="2004-07-05" version="1">MFKWLKSKFFKNKNNDKYQLGLKKTKASFLDFQTLLKQSNNIEKTLLQALESLLIQADFGTKTTLFLMQAIKDEINQFQIKNPQKLPSVVVSKMFDLYQNMKGMKGILESPKEQEKQNQYSNSTNPKDTFQSQNNLPQMYLFTGVNGVGKTTTIGKMAEALKQEGKKVLLIAADTFRAGAVEQLQIWAKRVGVEVFCKPLPAHPASVIFEGIELAKSQNYDIILCDTAGRLQNKTNLMQELSKINRVICKHLPASNLQTFLVLDATTGQNAINQVDLFNQATPLSGAILTKLDGTSKGGIVFAIKYLYNLPTKYIGVGEKSQDLITFDVKNYLFNLFEAFFTSEDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPP8</accession>
    <name>Q6YPP8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">PAM_677</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_677"/>
    <dbReference type="EnsemblBacteria" id="BAD04762">
        <property type="protein sequence ID" value="BAD04762"/>
        <property type="gene ID" value="PAM_677"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_677"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_789501_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-826-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="67"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="351" mass="40562" checksum="C9C79C218E6F9F98" modified="2004-07-05" version="1">MMPINPPTKFSAHPLVSQRRKETNDDIVNNISFANIIGMETEKETCNFILAMVSHPEWFQNAGKINTPKRFLLHGVPGTGKTLLARAFISQARQASPSTDAGCFEFTPSDFITKTREEGIEIIRAMFDFIRAEWHLNKNNGMGVILIDECDQVWKKMELINQEDQKMKDILNAFKAEITSLRSHCPHNPDAFIFVIGATNHLDQIDDAIKSRLNYHIEVKPLDTNGRKKFLEFLIEKRKTPITSTAKEYLLTTINDVLEKLTDKSKTGQRTMEYLLDDAIINACYETQGQSDIRIEDLKNLLKLFMDLICLKDFIKKLIIIKIIKSFYKRNKIKTQTKPCILRKFFQTFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPQ0</accession>
    <name>Q6YPQ0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">polA</name>
        <name evidence="2" type="ordered locus">PAM_675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_675"/>
    <dbReference type="EnsemblBacteria" id="BAD04760">
        <property type="protein sequence ID" value="BAD04760"/>
        <property type="gene ID" value="PAM_675"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_675"/>
    <dbReference type="eggNOG" id="COG0749">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_568409_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-824-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="480" mass="56505" checksum="0E7B8950FA31709A" modified="2004-07-05" version="1">MAQIQPYQIWACFFELEKENDSNTFLQGIGFSNENTHFFIDANLAFANNNFCNYLKDANFYKIVFHNQATQLFLKTKHQELNGVIFDLVCASYLLFPLKNLEFSHIIAKIDILNNTNYVSQLSQNIFILEQKVAFKAFLLHAIKNSVLHHLKAQNQLFLFQEIELPLSNILAQLEYETNLVKQKQIIEAQPIEKNTDEKIETQQEKIPKTNQRQEQEQAQEKEKDADQNQDTNTKLKNNQEQKQETHINQLKSFKDVFGYQNSCFLNIINNKKSYNYLINDNFFCFSLKILATLGNIQKIKNYFKIENNHLLNDEQTLQFFVNAPKSEIKKDSQKLSETTNFDVDAWTKAIIPELNISSNCAQDFIHQYLSLDDEIINYYQSLLQQIKEKKYALTLLKRKVFFGNQKLTPNFDLETLYVFLQENILDMKKIVILQLLRHLERNNETAKITYFALNDYLQQNIDLISKHLNYFFILDNGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPQ6</accession>
    <name>Q6YPQ6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_669</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04754">
        <property type="protein sequence ID" value="BAD04754"/>
        <property type="gene ID" value="PAM_669"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_669"/>
    <dbReference type="HOGENOM" id="CLU_1494807_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-815-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="180" mass="21587" checksum="A787C7D30C7F02A7" modified="2004-07-05" version="1">MGCIFGYDKTQKIRIKQRYFTSEGRVNWQDEDSWDREFDELGRIIKSIIYTSDSNSEEDKQVNWDSDYTYYCFYDQQGKQLHSVTRNRHYKLENGKIQVDWASEKTFDQKFNDDGSRNMRYFTQDGKINWENENTCNYDAIGNTQNLEGTQISSQERELEGKLQVYKKEAYNYVLEIEIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPS7</accession>
    <name>Q6YPS7_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YqaJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_391</name>
        <name evidence="3" type="ordered locus">PAM_648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04476">
        <property type="protein sequence ID" value="BAD04476"/>
        <property type="gene ID" value="PAM_391"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04733">
        <property type="protein sequence ID" value="BAD04733"/>
        <property type="gene ID" value="PAM_648"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_391"/>
    <dbReference type="KEGG" id="poy:PAM_648"/>
    <dbReference type="eggNOG" id="COG5377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1209247_0_0_14"/>
    <dbReference type="OrthoDB" id="1563636at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-468-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-789-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017482">
        <property type="entry name" value="Phage_endonuclease_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03033">
        <property type="entry name" value="phage_rel_nuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ" evidence="1">
        <location>
            <begin position="11"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="212" mass="25214" checksum="69EB087BB0E7C0C7" modified="2004-07-05" version="1">MQIKLSQRTKEWYQHRKQYINASEIASITGLDPFRSMEQLVHDKLFGTTFTANQYTLHGQKMEPIARQFFIQKTNLIFEDTIFTDDQVNLFSASLDGYNEQHQAVLEIKCPFVNENQEVSSTWTSFLTNPHLENIPQYYWAQVQCQLYCSQTKFAYFLVYFNNQSYHVVRIYQDKTFITKMIKDSQKYLALFTKAKEELEKTTYLKQLSKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPT1</accession>
    <name>Q6YPT1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA primase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dnaG</name>
        <name evidence="5" type="ordered locus">PAM_644</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_644"/>
    <dbReference type="EnsemblBacteria" id="BAD04729">
        <property type="protein sequence ID" value="BAD04729"/>
        <property type="gene ID" value="PAM_644"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_644"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620870_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Toprim_N" evidence="4">
        <location>
            <begin position="155"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="410" mass="48599" checksum="112FBF443E490F70" modified="2004-07-05" version="1">MNYQEKIKHIQTHFPMSVLLKKLKILSLNFNNQHRFPCPIHQGKNPTCCHFTSNNKIHCWKCGKDYDLIDVYMVIRQIKSFSEAIQRIEGFMNSFEFKTLSQQEKETTKITINPLKQLYHSMKPKQPVDEQEINIKKKQLFQKISPLFNQIRDYYHYLLTTNRNNESQPGLTYLTKKRKLTLETIKEFKLGYAPLSDKSLSFRLVNYCKKQNIDTTKLVEYGFIKEKISQQGKKYFHDTFHGSIIIPVENGYNKTFHFYQNHFREVSYFQPKYQALTNFSQTPTFHFSYRFFLKLYHILNKQKPSSFMKVFFDVISCWQNNIKNVVGLICVAQLLSQSQLTILKKENIKVIIALDNDETGQKRSEALGEQLTSHQIPYEIRHILPLTTKLVKMSMIYYVNTEKKLTTNVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPT7</accession>
    <name>Q6YPT7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04723">
        <property type="protein sequence ID" value="BAD04723"/>
        <property type="gene ID" value="PAM_638"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_638"/>
    <dbReference type="HOGENOM" id="CLU_3313674_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="39" mass="4621" checksum="A0B06DEA6994874B" modified="2004-07-05" version="1">MKNIFRFGSWLLLALLNYLVNIFSFCQFRCFCKSGIGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPV3</accession>
    <name>Q6YPV3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YqaJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_622"/>
    <dbReference type="EnsemblBacteria" id="BAD04707">
        <property type="protein sequence ID" value="BAD04707"/>
        <property type="gene ID" value="PAM_622"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_622"/>
    <dbReference type="eggNOG" id="COG5377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1209247_0_0_14"/>
    <dbReference type="OMA" id="QAQIYCS"/>
    <dbReference type="OrthoDB" id="1563636at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-757-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017482">
        <property type="entry name" value="Phage_endonuclease_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03033">
        <property type="entry name" value="phage_rel_nuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ" evidence="1">
        <location>
            <begin position="10"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="192" mass="22628" checksum="6FF0EF9A42830FFA" modified="2004-07-05" version="1">MQLEQNTLAWHNHRKKYINASEVAAIMGLNPFETKEQLLKRKVFGTPIEDNEAMKRGRILEPQARNFFNQTQKMQFEPKVFVKDFMSASLDGWDAQSQSLLEIKCPISFASYTWQSFLNEGKMPTIYYAQLQAQIYCSQSIKAYFLVYQNDQTNKNIEVKEDPNFITNMLEQCSHFFQLYLKTKQLQKQLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPW5</accession>
    <name>Q6YPW5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="Q6YPW5"/>
    <dbReference type="STRING" id="262768.PAM_610"/>
    <dbReference type="EnsemblBacteria" id="BAD04695">
        <property type="protein sequence ID" value="BAD04695"/>
        <property type="gene ID" value="PAM_610"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_610"/>
    <dbReference type="HOGENOM" id="CLU_1700636_0_0_14"/>
    <dbReference type="OMA" id="EYYKEST"/>
    <dbReference type="OrthoDB" id="1740280at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-736-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="155" mass="17936" checksum="28AEC7CC9605DF01" modified="2004-07-05" version="1">MKFLATKRGKIITGIIFITVTLYVGLGFYISFNPVNWLSPKKVWAKQAAQNLYNSVEKLTKEENKGNVNSKLAIIKTNLEAVNKHVIEYYKESTSNEYEVVKDLYEKIVKEKDDAYDYLQKNDNKADDTIFSNIKKLFKNDNAKNLQEKVNNLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPW9</accession>
    <name>Q6YPW9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04691">
        <property type="protein sequence ID" value="BAD04691"/>
        <property type="gene ID" value="PAM_606"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_606"/>
    <dbReference type="HOGENOM" id="CLU_1999151_0_0_14"/>
    <dbReference type="OMA" id="LEVKVRY"/>
    <dbReference type="OrthoDB" id="1698452at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-731-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="111" mass="12921" checksum="E306A95BB7BA7404" modified="2004-07-05" version="1">MECMQQAIVKNFYLEVKVRYLKQNGSSKRQWFATNVCVGTDNCKQKYDEVLMNFTHIDADNPEFFLQPGQVIKVLEGKVKQSKCGTVSEVWLDVDSFRQTDEEEKSKINFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPX4</accession>
    <name>Q6YPX4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiamine pyrophosphate-dependent dehydrogenase, E1 component beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">acoB</name>
        <name evidence="2" type="ordered locus">PAM_601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_601"/>
    <dbReference type="EnsemblBacteria" id="BAD04686">
        <property type="protein sequence ID" value="BAD04686"/>
        <property type="gene ID" value="PAM_601"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_601"/>
    <dbReference type="eggNOG" id="COG0022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012907_1_0_14"/>
    <dbReference type="OMA" id="SEAYYMA"/>
    <dbReference type="OrthoDB" id="900125at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-725-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="4"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="324" mass="35258" checksum="02F10AE2EB31416D" modified="2004-07-05" version="1">MASMTLLDAINQTLDSKLAKDPRVVLFGQDVGKLGGVFRVTKGLQDKHGETRVFNAPIAESSIIGSAIGLAINGMRPVAEIQFDGFIFVGLEDLFAHAARLRNRSRGNYTVPMVVRVPVGGGVKSLEHHSESLEVILGSVPGLKVVIPSNPYDAKGLLMAAINDPDPVVYMEPKRIYRGFRQEVPETDYEVQIGKAKVVQEGTDITVVAWGAMVPETLLALKQLDPNVSVELIDLRTINPIDRETVITSVKKTGRFLVVHEACKTYGPAGELMALVNEQAFLYLDAAPARVTGNDITMPLAKAEHYQFLSPEKIADAIKKVVCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ01</accession>
    <name>Q6YQ01_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tra5</name>
        <name evidence="2" type="ordered locus">PAM_574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_574"/>
    <dbReference type="EnsemblBacteria" id="BAD04659">
        <property type="protein sequence ID" value="BAD04659"/>
        <property type="gene ID" value="PAM_574"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_574"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_4_3_14"/>
    <dbReference type="OMA" id="FTSMEWA"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="150"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="312" mass="37579" checksum="A22138F9927F45A4" modified="2004-07-05" version="1">MQKLKQKIKLLQKIIKKIKKIDKKIVFHLVNQFNQTLNLTTILKTIQIKRSTYYYWLKVKAKLKEKEEKYLLQQKRIKALCLHYQYFYGHRKITDLYQKTFNEFITKKKVYLIMKKNEISCRLRIKKNFTYRNLKNNLQIIPNLINQDFMATKPLQKLFTDITYFKTNQGFLYFSCIIDSFNNQIIAFHTSNQQNKDLVLNTIKKLPKIINPCIIHSDQGKVYQSLKIQKTLTKKGFLISMSRKATPRDNAIIENFFGQMKTILQHQNPFLFQKSPDKMKKLINHFLKFWNNQWILSKLNYSTPSQYIQNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ08</accession>
    <name>Q6YQ08_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tra5</name>
        <name evidence="2" type="ordered locus">PAM_567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_567"/>
    <dbReference type="EnsemblBacteria" id="BAD04652">
        <property type="protein sequence ID" value="BAD04652"/>
        <property type="gene ID" value="PAM_567"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_567"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_4_3_14"/>
    <dbReference type="OMA" id="HDVARCT"/>
    <dbReference type="OrthoDB" id="1637053at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-685-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="151"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="309" mass="37106" checksum="75607AFCE473E26B" modified="2004-07-05" version="1">MQKLKQKINLLQQIIKKIEKIDKKIIFNLVEKFQNVLNLTTILKMIQTKRSTYYYWLKVNHKIKIKQEQYLLKQKRIESLCKMHEYLFGHRKITHLYQKIFNEPITKKKVYFIMKEKGICCRLRSKKNKYHYQQLKSQLKIVPNLINQDFKTYKPMQKLFTDITYFKTPQGFLYFSCIIDSFNNQIVASHVSNHQNKNLVLNTIKKMPKLKKPCIIHSDQGSVYQSLKIQHTLTKKGFLISMSRKAAPRDNAVIENFFGQMKSILFYRDPFLFQNPMTKMKTIINQFPAFWNKKWILAKLNYLSPIQYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ13</accession>
    <name>Q6YQ13_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_562"/>
    <dbReference type="EnsemblBacteria" id="BAD04647">
        <property type="protein sequence ID" value="BAD04647"/>
        <property type="gene ID" value="PAM_562"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_562"/>
    <dbReference type="HOGENOM" id="CLU_115718_0_0_14"/>
    <dbReference type="OMA" id="IDYRIES"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="176" mass="20355" checksum="C5CF2D1E9D47B412" modified="2004-07-05" version="1">MNKNIKNKNKILTIITIIIAIFFTTTSIFALTNYFSKQRKEKIQLMNNLPFFTIERTGGNNEDKTLLPIPIPNLNEQKYNYLITIEHEATLNSNGMDINVPLYLKISTKYDTLQTFTNPEKYLNVGLKVDNNDYDDTKRPQIRLNDKGIGSLKIQISIEQKEIITNKNPQLELICD</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ14</accession>
    <name>Q6YQ14_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflB</name>
        <name evidence="5" type="ordered locus">PAM_561</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_561"/>
    <dbReference type="EnsemblBacteria" id="BAD04646">
        <property type="protein sequence ID" value="BAD04646"/>
        <property type="gene ID" value="PAM_561"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_561"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056130_0_0_14"/>
    <dbReference type="OMA" id="GILMYGI"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000641">
        <property type="entry name" value="CbxX/CfxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00819">
        <property type="entry name" value="CBXCFQXSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="147"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="41"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="370" mass="42323" checksum="5F2558BC5B6E103F" modified="2004-07-05" version="1">MNIKNKSNKNSTNLIIIIIISMVLFLGTYVWIHHQTLTETEKNLITHHKKLENQNKNLQEIKDKLQQNKDIIQNQITNTNKESQETTNTNLQQLNNQEESNFHPSNNQKFPSFDQLIGFKEEKQAVEGFIDYLNNKENYNNIGEVDSPLGILMYGIPGTGKTTLARALAKETNLPFFEVSSSIFSQKYKGIAPQIVKDLFMTAREEAQKGKGAIIFLDECETIFTDLSGLEAGSEITNVVNQFKTEMTSFENDPVHPIFIIGATNHIDQIDEAIKSRFTYNIEVKPGNKEERKAFLEFLINKRKNPYSEEAKQYLYEVINESLEKLPHDQSFKKANRTLENLLKQAVIIFAKNRGPARAVDHACPNQLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ22</accession>
    <name>Q6YQ22_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YqaJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04638">
        <property type="protein sequence ID" value="BAD04638"/>
        <property type="gene ID" value="PAM_553"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_553"/>
    <dbReference type="eggNOG" id="COG5377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2047294_0_0_14"/>
    <dbReference type="OMA" id="HQEVPIN"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ" evidence="1">
        <location>
            <begin position="5"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="120" mass="14360" checksum="8E665D086CF8DD30" modified="2004-07-05" version="1">MFSASLDGYNAKTNTLLEIKCPYVDENNNISSTWNVFFFHQEVPINYWAQVQCQLYCSQAKFAYFLVYFNDNDYHVVRIYLDNNFITKMIQDSKQYLELLSKTKQELSQTTYLKRLSKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ26</accession>
    <name>Q6YQ26_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA primase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dnaG</name>
        <name evidence="9" type="ordered locus">PAM_549</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_549"/>
    <dbReference type="EnsemblBacteria" id="BAD04634">
        <property type="protein sequence ID" value="BAD04634"/>
        <property type="gene ID" value="PAM_549"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_549"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620870_0_0_14"/>
    <dbReference type="OMA" id="WITESEI"/>
    <dbReference type="OrthoDB" id="1071997at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-659-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0639">Primosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="302"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="441" mass="52505" checksum="EEBCA52F1C8F5C36" modified="2004-07-05" version="1">MNYQDKINHIKTNFPMIVLLKKLNIIPPNFNTKYRFPCPIHQGNNPTCCHLTSDNKIHCWKCCKDYDIIDVYMEIRGIKTFNNALEKINNFMKTQEFKNLIQQQTSTPNISYKPFKYQFQPNKINNPIDEKEINTTKTQLFKEISPLFNQIRDYYHYLLTTNRNNESHLGLEYLTQKRKLTLETIKEFKLGYAPLSDKPLSFRLVNYFKKKNINIDQLLEYGFIKEKTNQQNKKYYHDTFHGSIIIPIENGYNKTFHFYQNHFRDTTYFQPKYQSLNNFSQTPTFHFSYRFFEALPYIKKTKTIIIHEGFFDVISCWQHGIKNVVGLICVAQLLSQTQMDILKKEKIKVITALDNDETGRKRNAALGEQLKEQQIPYEIRRILSPYDKTCKDVDDLLRQYGKEAYQKCFLDPYISYEEAEKKQIVDLAIHFFGEDKVEVMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ31</accession>
    <name>Q6YQ31_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thymidylate_kin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_544"/>
    <dbReference type="EnsemblBacteria" id="BAD04629">
        <property type="protein sequence ID" value="BAD04629"/>
        <property type="gene ID" value="PAM_544"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_544"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1946601_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-652-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="1">
        <location>
            <begin position="7"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="126" mass="14850" checksum="FE478193B9FA2741" modified="2004-07-05" version="1">MMKLIVFEGHSGRGKTSLINSLRPHLKNPYQLYQGLGSSSLGKEIRGLFLNFQQVDYLTRFYLSLANMSQIQAELFKNHQLIILDRWLPSTYAYQLFPFFKEKKQLLPLKKIFKLNHETILKNPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ39</accession>
    <name>Q6YQ39_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase specialized sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fliA</name>
        <name evidence="2" type="ordered locus">PAM_536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_536"/>
    <dbReference type="EnsemblBacteria" id="BAD04621">
        <property type="protein sequence ID" value="BAD04621"/>
        <property type="gene ID" value="PAM_536"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_536"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110732_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="47"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="228" mass="27061" checksum="E4D7CF526845DDB1" modified="2004-07-05" version="1">MFFKRNKKKKLYSSFLKTFLERIQMKRKDLFLLFLKNKKNFEIRDQLIELHLPLVKKISSKFKYYPKLLTKEDLYQEGILGLIKALDNYQDLGYDFIAYATPTIKSTINELIRKSHSPSIPQKTTKPNNISFKEQHYEPDRITNPNPHQLWLKQVNHEQLIKKLKSKLSKNEFNVICLSFGITLENITKNHQPTFTNQEISQKLNLNLRQVETIKNIAIRKLSPNNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ44</accession>
    <name>Q6YQ44_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04616">
        <property type="protein sequence ID" value="BAD04616"/>
        <property type="gene ID" value="PAM_531"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_531"/>
    <dbReference type="HOGENOM" id="CLU_2168401_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-635-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="110" mass="12989" checksum="7294952A69461C09" modified="2004-07-05" version="1">MDKQQKLKKEFYEHCQFCGSDLGININAACLNLFGFIMSFISFISCGILLLYSSLIFLLRYFFTVIIFNEEFFLTIGLISVISLFLFYLIARFMPKLLFEKLDYEKVEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ47</accession>
    <name>Q6YQ47_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2963 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_528"/>
    <dbReference type="EnsemblBacteria" id="BAD04613">
        <property type="protein sequence ID" value="BAD04613"/>
        <property type="gene ID" value="PAM_528"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_528"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065991_1_0_14"/>
    <dbReference type="OMA" id="IYYIEEY"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="134"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="260" mass="30807" checksum="A0ECED31403A5867" modified="2004-07-05" version="1">MSSFRIGNKHYKIIPFLITTGTLIFFVFWIGGLAYKYHLETEERRKLQEVDIKAKARELNNDIYNENKKLKKENEYMKDTPYEFQRDNGEKEYYNLFTNKLVKKIDKDDTIWEYDKNNGLLLKKTDRYNNVEEYGSHGKLIKKTLSDGVWMEYNPVNQKLMKRKNIDNSIEEFDDNEEKFKEIDKNGKVKFFKTKLYQNISDFKKLNLTIEQLKDIGFTFQQYKSAGYTVEQLKSVGFGAKELKDAGFSLQELKAAGYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ48</accession>
    <name>Q6YQ48_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">uvrD</name>
        <name evidence="8" type="ordered locus">PAM_527</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_527"/>
    <dbReference type="EnsemblBacteria" id="BAD04612">
        <property type="protein sequence ID" value="BAD04612"/>
        <property type="gene ID" value="PAM_527"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_527"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011020_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-631-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="3"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="1038" mass="124589" checksum="7B9DF36A26143515" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ57</accession>
    <name>Q6YQ57_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_518"/>
    <dbReference type="EnsemblBacteria" id="BAD04603">
        <property type="protein sequence ID" value="BAD04603"/>
        <property type="gene ID" value="PAM_518"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_518"/>
    <dbReference type="HOGENOM" id="CLU_1881478_0_0_14"/>
    <dbReference type="OMA" id="MYIFWQY"/>
    <dbReference type="OrthoDB" id="1786336at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-621-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="135" mass="16045" checksum="577E33B25C8DE0AA" modified="2004-07-05" version="1">MFKFQHNLLFLNIFIFILLGFFLITNNNQVIAAPHEERVGDMRIVNITFSDINSIKNFQPFSQYFDFTLTGPRYNGNIAQFAMIWKIKNPPHNLLGVFFDNNTRDDEDDKYTLEELKQMGNGAKNMYIFWQYEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ66</accession>
    <name>Q6YQ66_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04594">
        <property type="protein sequence ID" value="BAD04594"/>
        <property type="gene ID" value="PAM_509"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_509"/>
    <dbReference type="HOGENOM" id="CLU_2992272_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="57" mass="7027" checksum="AF61B6CEBE8ADCC6" modified="2004-07-05" version="1">MMDIQQTIINIVESKVFISFTSFIFGIFIYWLYFYIKELKSKYDFSDELRDIVNHYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ69</accession>
    <name>Q6YQ69_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_506"/>
    <dbReference type="EnsemblBacteria" id="BAD04591">
        <property type="protein sequence ID" value="BAD04591"/>
        <property type="gene ID" value="PAM_506"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_506"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1228877_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="119"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="153"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="179"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="225" mass="26139" checksum="18E0AB7E0B69DE7B" modified="2004-07-05" version="1">MKRKNIDNSIEEFDDNEEKFKEIDKNNKVKFFKTKLYQNISDFKKLNLTIEQLKDIGFTFQQIKEAGYTAKELKDAGLSLQELKDAGYTAKELRVAGFTFQQLKDIGFTFQQIKEAGYTAEELKQITYYSDGTINYIDEFDPQTGKLINRNPNGTINYIDEFDPQTGNKIKHTLYISNIIDAITEYDPQTGNRIKHTEYNSNGETIYSITEYNKFDGTIKKVQTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ88</accession>
    <name>Q6YQ88_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type amino acid transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">artM</name>
        <name evidence="7" type="ordered locus">PAM_487</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_487"/>
    <dbReference type="EnsemblBacteria" id="BAD04572">
        <property type="protein sequence ID" value="BAD04572"/>
        <property type="gene ID" value="PAM_487"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_487"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_1_14"/>
    <dbReference type="OMA" id="ESFLWPW"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-573-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="19"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="232" mass="27352" checksum="0BEA89137E685B3E" modified="2004-07-05" version="1">MKNCYNLFINNLPSYWNVICTTISLAFLGTLGAFFLSLWLLYIKGIRKKKRIRFYERYFYKTIDIILYFYIFFVKSVPMMLQAMLFFYGLRRTGCFEWLEPFQAALFILIFNSCAMLAEFMIKNMSFFDPGQIEASLALGMTRKQAFKRVICPQVIHQSLLRIINEFILNIKDICVFYVITVVDIFTFSKNNYRTSNNFGFLINASLIYIILIFISSYLLKKLETKLGNKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ91</accession>
    <name>Q6YQ91_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04569">
        <property type="protein sequence ID" value="BAD04569"/>
        <property type="gene ID" value="PAM_484"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_484"/>
    <dbReference type="HOGENOM" id="CLU_1212791_0_0_14"/>
    <dbReference type="OMA" id="FCVIYLD"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="77"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="145"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="201" mass="23891" checksum="771B5FFBFC8C1F8E" modified="2004-07-05" version="1">MCLILMVIIMFLSSFILYNKERKDKIFTQKKESTKLPNPIIQENKPNKENNNEIVNQNKLISNENNLIVTNSNENTQMINIYDSITNNLIKKTTFYPNQKTINFIEKYNPQTKKCLQIKHFTQQGTLFCVIYLDQNTKKITKIIYYQDNNKIDNEAKYSLQTGKKISHTYYLKNGIDIDYIDKYNEKEEISETIHYIVTKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQA7</accession>
    <name>Q6YQA7_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">csdB</name>
        <name evidence="7" type="ordered locus">PAM_468</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_468"/>
    <dbReference type="EnsemblBacteria" id="BAD04553">
        <property type="protein sequence ID" value="BAD04553"/>
        <property type="gene ID" value="PAM_468"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_468"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_5_14"/>
    <dbReference type="OMA" id="HKLCGPT"/>
    <dbReference type="OrthoDB" id="446447at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-553-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="20"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="401" mass="45478" checksum="63B365119A7EF359" modified="2004-07-05" version="1">MQNNPFRCLFPIFKTNPKIVYFDNAATSLKPQKVIDELTRFYNTNGLNTKSFGVLSHQNTLLMNETRIKTANFINSKPEEIIFTKGTTDSLNILAQSLGETLQEGDEIITSELEHNSSVIPWFKQAKLKKAKLIFVPLNEQNQITVENFAKVLTNKTKIVVLTHVSNLLGYETPIKEITTLAHKKNALVILDSAQSSSHLPIDVKFLDVDFLAFSSHKLYGPFGIGILFGKNHLLEQLQPPSFGGTSIKEFSLKHFLLNEGPNKFESGTPNISGILAFKKALEFVEEIGFENIQKHEKKIYQNIMKELKQIPKITIYNPQAFSNIITFNFNQIHAHDAEAFLAQENIYVRTGRCCAFLATQKLKQTSIIRVSIGIHNNQEDVDILIKNLKKTQTFFSKFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQB2</accession>
    <name>Q6YQB2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04548">
        <property type="protein sequence ID" value="BAD04548"/>
        <property type="gene ID" value="PAM_463"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_463"/>
    <dbReference type="HOGENOM" id="CLU_1738655_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="150" mass="17612" checksum="BD66EF9076835D7A" modified="2004-07-05" version="1">MELRLVKQEEGKFLDIIDLKNKLNSLENKLERLANPETQITHENEEIKITTKQIEQLVKITDIDTLKAKLKELTNPLEQNKSILSDNEKQNLINEIAKTKKQITNIEKITKKWVDDIFENHQETINLAKIILGHKLEKLFHLIKKDLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQB5</accession>
    <name>Q6YQB5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_460"/>
    <dbReference type="EnsemblBacteria" id="BAD04545">
        <property type="protein sequence ID" value="BAD04545"/>
        <property type="gene ID" value="PAM_460"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_460"/>
    <dbReference type="HOGENOM" id="CLU_155207_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="109" mass="12607" checksum="FD91A6150CE40673" modified="2004-07-05" version="1">MFDFLMQILKIFIDVFGSIIGYIKSSITSLTGQKLMDPSESMWEKIKEIAKLIFSVSVGGSVIYFLKEINNFLLNSFIKIGDLLFKIVLRILDIISIVLKFFLFFLKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQB8</accession>
    <name>Q6YQB8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC-type amino acid transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">artI</name>
        <name evidence="10" type="ordered locus">PAM_457</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_457"/>
    <dbReference type="EnsemblBacteria" id="BAD04542">
        <property type="protein sequence ID" value="BAD04542"/>
        <property type="gene ID" value="PAM_457"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_457"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_20_3_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-541-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018313">
        <property type="entry name" value="SBP_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01039">
        <property type="entry name" value="SBP_BACTERIAL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="575"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="397"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="331"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="609" mass="69592" checksum="4A0601C802A93A90" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="134" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQC7</accession>
    <name>Q6YQC7_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Lon protease</fullName>
            <ecNumber evidence="6 7">3.4.21.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-dependent protease La</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 14" type="primary">lon</name>
        <name evidence="14" type="ordered locus">PAM_448</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 10">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6 7">Homohexamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="6">By heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7 10 11">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="6 7"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_448"/>
    <dbReference type="MEROPS" id="S16.001"/>
    <dbReference type="EnsemblBacteria" id="BAD04533">
        <property type="protein sequence ID" value="BAD04533"/>
        <property type="gene ID" value="PAM_448"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_448"/>
    <dbReference type="eggNOG" id="COG0466">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004109_4_3_14"/>
    <dbReference type="OMA" id="GAWQVVD"/>
    <dbReference type="OrthoDB" id="128102at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-529-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01973">
        <property type="entry name" value="lon_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027543">
        <property type="entry name" value="Lon_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="13">
        <location>
            <begin position="28"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="12">
        <location>
            <begin position="611"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="active site" evidence="6 8 10">
        <location>
            <position position="698"/>
        </location>
    </feature>
    <feature type="active site" evidence="6 8 10">
        <location>
            <position position="741"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 9">
        <location>
            <begin position="375"/>
            <end position="382"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAD04533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="791" mass="89819" checksum="A5868F6CBC1AAED0" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQG0</accession>
    <name>Q6YQG0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">uvrD</name>
        <name evidence="6" type="ordered locus">PAM_413</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_413"/>
    <dbReference type="EnsemblBacteria" id="BAD04498">
        <property type="protein sequence ID" value="BAD04498"/>
        <property type="gene ID" value="PAM_413"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_413"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011020_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="5">
        <location>
            <begin position="61"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="5">
        <location>
            <begin position="157"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="810" mass="97378" checksum="70698DA736CC70FA" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="111" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQG3</accession>
    <name>Q6YQG3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_410"/>
    <dbReference type="EnsemblBacteria" id="BAD04495">
        <property type="protein sequence ID" value="BAD04495"/>
        <property type="gene ID" value="PAM_410"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_410"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OMA" id="EVICRYM"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-493-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="111" mass="12965" checksum="30EBFDFC27696C57" modified="2004-07-05" version="1">MLNNIQLIGRITHDLEKQYINSNNEQIPKIDFQLAVNQTKDKVQYIPCVVFRTQAENFHKYLHKGSKIYLEGTLSIQKYTNNEGQNKTNTKVIVHKVIFLDNKSQTDNLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQH5</accession>
    <name>Q6YQH5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">PAM_398</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="7526">
        <property type="entry name" value="M.PhsOYORF398P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04483">
        <property type="protein sequence ID" value="BAD04483"/>
        <property type="gene ID" value="PAM_398"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_398"/>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140323_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="111" mass="13490" checksum="E72A25892C452161" modified="2004-07-05" version="1">MKINWIGCKKKLLPQIISHLPKQFKTYYEPFLGSGVLYFYLKSSKAILNNNDRQLITMWKQSLQNHHHFVNKFKAIENYIYQYHNQQNQKQAFKNLLNQYNQNIKKKKKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQI1</accession>
    <name>Q6YQI1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_392"/>
    <dbReference type="EnsemblBacteria" id="BAD04477">
        <property type="protein sequence ID" value="BAD04477"/>
        <property type="gene ID" value="PAM_392"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_392"/>
    <dbReference type="HOGENOM" id="CLU_1745933_0_0_14"/>
    <dbReference type="OMA" id="FHLEIRN"/>
    <dbReference type="OrthoDB" id="2134005at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-471-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="151" mass="18119" checksum="048687ED4D6CDEE0" modified="2004-07-05" version="1">MNLNLKNINYTSIFLFIIFLFFIFINYFIKSNLVYAGQVYSEIKKTDSSEQLFDSSETKIEFLRSKIDDLSRKRNSILKEINRIEETLSFHLKIRSKKNPNVSERNSSFLKFQISFLKEKKSFLKKNLEQINLEQIDLEIQLRKKIYSLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQI7</accession>
    <name>Q6YQI7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04471">
        <property type="protein sequence ID" value="BAD04471"/>
        <property type="gene ID" value="PAM_386"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_386"/>
    <dbReference type="HOGENOM" id="CLU_1319854_0_0_14"/>
    <dbReference type="OrthoDB" id="1617013at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-462-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="208" mass="24817" checksum="8E2B31AD46DE214F" modified="2004-07-05" version="1">MKNDASQEIRIGGWNAKATPNDLTQIKNFLKILKEDLINLTIISHSKKKNTYQEANYRPKNQTLFVDPQILEEIKQTKITLINDNFSSINSKLLLSDLTPLKRQNNPLKHLFNIFQINYKNEFKNTIKELIRKIDGNKLETLQLYQLDPQKLDKYHKPMKTNYKKGLNIIYYRQEDLKYLQSFLTKDKQGYRVKKLHPKYKYIPKQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQI9</accession>
    <name>Q6YQI9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_384"/>
    <dbReference type="EnsemblBacteria" id="BAD04469">
        <property type="protein sequence ID" value="BAD04469"/>
        <property type="gene ID" value="PAM_384"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_384"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_41_5_14"/>
    <dbReference type="OMA" id="MITHHET"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="62" mass="7572" checksum="EF8F86B22E3B98CC" modified="2004-07-05" version="1">MITHHETFRPMKTSYTSKSILFQKSPDKMKKLINHFPKFWNTKWILNKLNHSTPPQYIQNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQL6</accession>
    <name>Q6YQL6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">himA</name>
        <name evidence="2" type="ordered locus">PAM_317</name>
        <name evidence="3" type="ordered locus">PAM_357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04402">
        <property type="protein sequence ID" value="BAD04402"/>
        <property type="gene ID" value="PAM_317"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04442">
        <property type="protein sequence ID" value="BAD04442"/>
        <property type="gene ID" value="PAM_357"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_317"/>
    <dbReference type="KEGG" id="poy:PAM_357"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_3_14"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-377-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-425-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="96" mass="11000" checksum="86F4E8A1BC47427F" modified="2004-07-05" version="1">MTKKELIKKIAEVNKTSISKTEEFYHIFEKTLIEAITTNEEVVLSPQIGKFQLKPRKAYIGRNPKTKKKLKIPAKTVVAFKLSKSIKDKAKTLILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQM5</accession>
    <name>Q6YQM5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome segregation ATPase homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">smc</name>
        <name evidence="2" type="ordered locus">PAM_348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_348"/>
    <dbReference type="EnsemblBacteria" id="BAD04433">
        <property type="protein sequence ID" value="BAD04433"/>
        <property type="gene ID" value="PAM_348"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_348"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115275_0_0_14"/>
    <dbReference type="OrthoDB" id="1592351at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-415-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="215" mass="25494" checksum="AD14B9FD9B47B42A" modified="2004-07-05" version="1">MTEQLQNQLQEQKTLIETKNQELITNQALSEQEKQELQNEINQLTTNFQQKEKEYQATIYQKDQEITHLNQIINKQANEINRLSEELEQQIDKWVQQGLHIEALEGTIKALENASGKYIEENAELRHEIETLKEKIKTEKTRHEKTKKTLKEKSDQLTTEKEELDKIDKILKNQEKTYSAAIQPLKACIKEDVRQRINSSKEKVNNVTSWFKKWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQN3</accession>
    <name>Q6YQN3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_340"/>
    <dbReference type="EnsemblBacteria" id="BAD04425">
        <property type="protein sequence ID" value="BAD04425"/>
        <property type="gene ID" value="PAM_340"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_340"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1935901_0_0_14"/>
    <dbReference type="OMA" id="ISYEPFE"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="122" mass="14579" checksum="026FE438B530C2C4" modified="2004-07-05" version="1">MNHQDKIKHIKTNFPMIVLLKKLNIIPPNFNTKYRFPCPIHQGQNPTCCHLTSDNKIHCWKCCKDYDIIDVYMEIREIKTFNNALEKINNFMKTQEFKNLNKQQKSITKISYEPFEKTISTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQQ9</accession>
    <name>Q6YQQ9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_314"/>
    <dbReference type="EnsemblBacteria" id="BAD04399">
        <property type="protein sequence ID" value="BAD04399"/>
        <property type="gene ID" value="PAM_314"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_314"/>
    <dbReference type="eggNOG" id="COG1357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2849">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065991_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-374-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="134"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="275"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="318"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="326"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="351"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="413" mass="48833" checksum="9074B88C4507D9E0" modified="2004-07-05" version="1">MSSFRIGNKHYKIIPFLITTGTLLFFVFWIGGISYKYHLETEERRKLQEVDIKAKARELNDLIYNENKKLKKENEYMKDTPYEFIRDNGEKEYYNLFTHKLVKKIDKDDTIWEYDKNNGLLLKKTDRYNNVEEYGSHGKLIKKTLSDGVWMEYNPINSKLMKRKNIDGSIEEFDDNEEKFKEIDKNGKVKFFKTKLYQNISDFKKLNLTIEQLKDIGFTFQQLKDAGYTAKELKDAGYTAKELKDAGFSLQELKASGYTLEQLISVGYTEKEIVYRSDGITIGYIKILDSKTKKEIKRTNYYEDGKTIYYITEYNHEGKLIKKTFYRPDGITIASIREFNSEEKLIKKTFYNLDGITIASIEKFNSEEKLIKRTNYYEDGKTIYYITEYNLKGGIKKETYFNPDGTVKEEITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQS9</accession>
    <name>Q6YQS9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="3">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">folA</name>
        <name evidence="8" type="ordered locus">PAM_294</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_294"/>
    <dbReference type="EnsemblBacteria" id="BAD04379">
        <property type="protein sequence ID" value="BAD04379"/>
        <property type="gene ID" value="PAM_294"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_294"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_5_2_14"/>
    <dbReference type="OMA" id="RDNQLPW"/>
    <dbReference type="OrthoDB" id="1920912at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-352-MON"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="7">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="163" mass="19091" checksum="883A475C8751959F" modified="2004-07-05" version="1">MINLITAFDGNYLIGKDNKLPWHYSQDLQYFKKITLNQNVLMGYETYKSLKNYFKNKPFNFKKTYVASLKHDLELPNCTVVSDLQSFMASDAAQDIFIIGGGKIYQQTLPWVTTLYITHILQRHQGNVFFPKIDLSQYQLIQKEIHPQLIFAIYQKKLDTPKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="124" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQU2</accession>
    <name>Q6YQU2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="11">6-phosphofructokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pfkA</name>
        <name evidence="11" type="ordered locus">PAM_281</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_281"/>
    <dbReference type="EnsemblBacteria" id="BAD04366">
        <property type="protein sequence ID" value="BAD04366"/>
        <property type="gene ID" value="PAM_281"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_281"/>
    <dbReference type="eggNOG" id="COG0205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020655_0_1_14"/>
    <dbReference type="OMA" id="TNRDNPF"/>
    <dbReference type="OrthoDB" id="1421302at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-339-MON"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="10">
        <location>
            <begin position="17"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAD04366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="332" mass="36218" checksum="E30FF999504BF32E" modified="2004-07-05" version="1">MKNENQKAKTKTKENKKIAVLTSGGDAPGMNAAIRALVFESAKQGFEVFGVKDGYLGLFNNQIEILNPQTFPRVLNVSGTFLGTSRFLDFQNNLDVRKQCAQNLKTLGIDKLVVIGGDGSYKGASKLHELGIKCVGLPATIDNDICATDFTIGFSTALNNIVDAIEKLRDTSVSHNRCSIIEVMGRHKGDLALFGGLAAGADVIVTRENLLSQKTICQKIKSLRQANQRHAIVVVTEHIFDVASLAKEVENYSGFETRAQVLGHIQRGGKPTAEDLVLAFRMGSYAVSLLQQNIFNCAVGTCGLNLHYTTFGDLFEKTYEKNELFNVVAKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQU6</accession>
    <name>Q6YQU6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_277"/>
    <dbReference type="EnsemblBacteria" id="BAD04362">
        <property type="protein sequence ID" value="BAD04362"/>
        <property type="gene ID" value="PAM_277"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_277"/>
    <dbReference type="HOGENOM" id="CLU_1044367_0_0_14"/>
    <dbReference type="OMA" id="NITKQFA"/>
    <dbReference type="OrthoDB" id="1172284at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-335-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="254" mass="30257" checksum="5E9540591C2EFF49" modified="2004-07-05" version="1">MSFWEKFFNITKQFAFFNTFFMGILSGVILSSFIYCLLSLCSVKKTLAAHRLEKTDVSQQEIIKLIEAKKKDFKEKMKKDKGNFGNFLITSIQELILEISIQFYPSSKYPYLELTIDESLILIFYINQRFDKVFQNKILRMFRKMTLKRIFVIREIVVKKNMIQKYQKVTKVTNTFNNIRNFFNPFHWFKKIIFDKPLELIYHQIGVSLIAITGEEVYKIYSKKIFETEEDLEKDLQKVLDTISKVSADQSEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQV3</accession>
    <name>Q6YQV3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized BCR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">PAM_270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_270"/>
    <dbReference type="EnsemblBacteria" id="BAD04355">
        <property type="protein sequence ID" value="BAD04355"/>
        <property type="gene ID" value="PAM_270"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_270"/>
    <dbReference type="eggNOG" id="COG1322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_766498_0_0_14"/>
    <dbReference type="OMA" id="EQNASGF"/>
    <dbReference type="OrthoDB" id="1309809at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-329-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30563">
        <property type="entry name" value="PTHR30563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="315"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="361" mass="42051" checksum="B93DA2CF956810A9" modified="2004-07-05" version="1">MPQDQIVFLLILTLSVILILILGSVTFIIYFFVAKPKKTQVNIQDFVKQAFLESESRVICRLDDKINNLTNQSQDSLTKEIKDTRQHLTINLENSLKVLREQNASGFQEVQNIHKLLCQNDKTGQAGEFLLARVLENVSHFKDKLVFEKQYLMKKTNNNGNRLKVDVMCKGYGKFVQIPIDSKFPTTDFLAYINATSNQTELKSRFLFHVKERIKEVQKYVSKEDNCPYAIMFIPSESIFAQINCDPEIISYAFKRNVIITSPSILLAILNSVDYYFQIFESVQNNEEKLECIENVLQAMKNFDKVFIYDLKAALEKVLKVIEDIQKKEKTLEQRYQKLLEVRKKENNNSKNNIKNEKIDF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-09-27" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQW1</accession>
    <name>RS12_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsL</name>
        <name type="ordered locus">PAM_262</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Because the enzyme that would modify Asp-102 to 3-methylthioaspartic acid has not been found in the proteome of this organism, that modification is not predicted.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQW1"/>
    <dbReference type="SMR" id="Q6YQW1"/>
    <dbReference type="STRING" id="262768.PAM_262"/>
    <dbReference type="EnsemblBacteria" id="BAD04347">
        <property type="protein sequence ID" value="BAD04347"/>
        <property type="gene ID" value="PAM_262"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_262"/>
    <dbReference type="eggNOG" id="COG0048">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104295_1_2_14"/>
    <dbReference type="OMA" id="SPALEKC"/>
    <dbReference type="OrthoDB" id="1707228at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-319-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_0000146279" description="30S ribosomal protein S12">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="139" mass="15277" checksum="67580CE5671BCD21" modified="2004-07-05" version="1">MSTVSQLIKKRRSSKTSKTKAPALSYGFNVLQKKAKHYSSPQKMGVCLRVTTMTPKKPNSALRKFARVRLSNGSEVTAYIPGVGHSLQEHSSVLVRGGRVKDLPGVRYHIVRGALDATGVANRKQGRSKYGSKLPKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-06-28" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQX0</accession>
    <name>Q6YQX0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rpmG</name>
        <name evidence="5" type="ordered locus">PAM_253</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_253"/>
    <dbReference type="EnsemblBacteria" id="BAD04338">
        <property type="protein sequence ID" value="BAD04338"/>
        <property type="gene ID" value="PAM_253"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_253"/>
    <dbReference type="eggNOG" id="COG0267">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190949_0_0_14"/>
    <dbReference type="OrthoDB" id="2034291at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-310-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168">
        <property type="entry name" value="PTHR43168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="61" mass="7221" checksum="25FEF98764E88DEB" modified="2011-06-28" version="1">MFFQLSNIKGAIFLKKNILVCVLCLNRNYNTKPRANQNSKRLTLKKYCSYCNKHTLHQETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="129" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQX1</accession>
    <name>Q6YQX1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation transport ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mgtA</name>
        <name evidence="7" type="ordered locus">PAM_252</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_252"/>
    <dbReference type="EnsemblBacteria" id="BAD04337">
        <property type="protein sequence ID" value="BAD04337"/>
        <property type="gene ID" value="PAM_252"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_252"/>
    <dbReference type="eggNOG" id="COG0474">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_5_1_14"/>
    <dbReference type="OMA" id="RLGRKQC"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-309-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="620"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="694"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="728"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="757"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1037"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="domain" description="SpoU_sub_bind" evidence="6">
        <location>
            <begin position="823"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="1056" mass="118474" checksum="781DA3EF3B1EAAEA" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQX4</accession>
    <name>Q6YQX4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Preprotein translocase subunit YidC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">yidC</name>
        <name evidence="9" type="ordered locus">PAM_249</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_249"/>
    <dbReference type="EnsemblBacteria" id="BAD04334">
        <property type="protein sequence ID" value="BAD04334"/>
        <property type="gene ID" value="PAM_249"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_249"/>
    <dbReference type="eggNOG" id="COG0706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_518594_0_0_14"/>
    <dbReference type="OMA" id="FIRTLTW"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-300-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="525" mass="61327" checksum="D1B0F3DC535444E0" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="112" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQX8</accession>
    <name>Q6YQX8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Xaa-Pro aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pepP</name>
        <name evidence="7" type="ordered locus">PAM_245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_245"/>
    <dbReference type="EnsemblBacteria" id="BAD04330">
        <property type="protein sequence ID" value="BAD04330"/>
        <property type="gene ID" value="PAM_245"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_245"/>
    <dbReference type="eggNOG" id="COG0006">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_1_0_14"/>
    <dbReference type="OMA" id="LHYGANN"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP_N" evidence="6">
        <location>
            <begin position="2"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="418" mass="47719" checksum="0BE5DEF8B893D521" modified="2004-07-05" version="1">MHNRNNFIQKMKPNTAALFYSGKAITKSGDQTFPLEVDHNFYYLTGINQPNTILLLVKTPNLSHTFLFLEENNPSKALWDGDILSFSDASLISQINLSNLKNILTFETFLFQMINPLRGSFVDSLEGFYFDLSKQTLDQKASWALEYCQKMTSLYPFLQVYNSSSFLFSLRQTKSVYEQTQIQKALDINHQALNYLLKNLKPGMYEYQIAALFHYFLENNQTQKSFETIAASGKNALILHYNKPNCQLKPNDLLLFDAGVTYNHYSSDITRCYPVSGQFSSLQKDIYNLVLKANKEIIAWVKPHHTFTQLNQYGKDILLQGLKKMSLLKEGETIHQYCYHGLGHHLGLDIHDVCNYTGVIGTNSVITVEPGLYLKDLGIGVRIEDNLLITQEGAVNLSKHIPKEVKDIEALMKPFVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQY1</accession>
    <name>Q6YQY1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">himA</name>
        <name evidence="4" type="ordered locus">PAM_242</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_242"/>
    <dbReference type="EnsemblBacteria" id="BAD04327">
        <property type="protein sequence ID" value="BAD04327"/>
        <property type="gene ID" value="PAM_242"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_242"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_1_14"/>
    <dbReference type="OMA" id="RDRVNIY"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-290-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="94" mass="10783" checksum="B2CC5AF298B3FC33" modified="2004-07-05" version="1">MNKLEFLRKLAEKNGVSQKEADKFLNNFIEVISQSLQEFKEDEKVTLTGFGTFEVKHRSAREGKNPRTGKTIDIPAKKVPTFKFSKSFKDLFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQY7</accession>
    <name>Q6YQY7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trxA</name>
        <name evidence="2" type="ordered locus">PAM_236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_236"/>
    <dbReference type="EnsemblBacteria" id="BAD04321">
        <property type="protein sequence ID" value="BAD04321"/>
        <property type="gene ID" value="PAM_236"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_236"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090389_22_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="83" mass="9666" checksum="7919869C3C389E48" modified="2004-07-05" version="1">MLIFLLHGGPPCQRLLPVLDEVCLLEKDILFYKVDVDFFRQLALEKGVSGFPTLILYKDKKELARHSGFLNKEDLLKFLHSYK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-08-16" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR06</accession>
    <name>RL18_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplR</name>
        <name type="ordered locus">PAM_216</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR06"/>
    <dbReference type="SMR" id="Q6YR06"/>
    <dbReference type="STRING" id="262768.PAM_216"/>
    <dbReference type="EnsemblBacteria" id="BAD04301">
        <property type="protein sequence ID" value="BAD04301"/>
        <property type="gene ID" value="PAM_216"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_216"/>
    <dbReference type="eggNOG" id="COG0256">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098841_0_1_14"/>
    <dbReference type="OMA" id="NKQIYAQ"/>
    <dbReference type="OrthoDB" id="1963491at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-262-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000131312" description="50S ribosomal protein L18">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <sequence length="117" mass="12992" checksum="CD11CACFDC9ADFC3" modified="2004-07-05" version="1">MITKQSSNVLRKKRHLRLRKIVSGTSQRPRLNVFRSNKFLYVQIIDDTQQTTLCSANSKESNVLGSNIKAAEAVGALIAKKALAQGIKNVVFDRSGYLYHGKIKALADACRKSGLQF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-11-25" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR09</accession>
    <name>RS14_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsN</name>
        <name type="synonym">pam213</name>
        <name type="ordered locus">PAM_213</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR09"/>
    <dbReference type="SMR" id="Q6YR09"/>
    <dbReference type="STRING" id="262768.PAM_213"/>
    <dbReference type="EnsemblBacteria" id="BAD04298">
        <property type="protein sequence ID" value="BAD04298"/>
        <property type="gene ID" value="PAM_213"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_213"/>
    <dbReference type="eggNOG" id="COG0199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139869_0_0_14"/>
    <dbReference type="OMA" id="FGLCRNQ"/>
    <dbReference type="OrthoDB" id="2032609at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-259-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00537">
        <property type="entry name" value="Ribosomal_S14_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_S14/S29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023036">
        <property type="entry name" value="Ribosomal_S14_bac/plastid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000354388" description="30S ribosomal protein S14">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00537"/>
        </source>
    </evidence>
    <sequence length="89" mass="10274" checksum="F22F0F71B8AFD8E1" modified="2004-07-05" version="1">MAKKSKIVKDQKQRELVLKYAKLRLELKKKADYAGLSQIPAKASPVRLKNRDSIDGRPRGYIRKFGISRINFRQLAHQGKLPGVRKTSW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-12-16" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR11</accession>
    <name>RL14_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplN</name>
        <name type="ordered locus">PAM_210</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR11"/>
    <dbReference type="SMR" id="Q6YR11"/>
    <dbReference type="STRING" id="262768.PAM_210"/>
    <dbReference type="EnsemblBacteria" id="BAD04295">
        <property type="protein sequence ID" value="BAD04295"/>
        <property type="gene ID" value="PAM_210"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_210"/>
    <dbReference type="eggNOG" id="COG0093">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095071_2_1_14"/>
    <dbReference type="OMA" id="AKEVLCI"/>
    <dbReference type="OrthoDB" id="1799923at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-256-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000355828" description="50S ribosomal protein L14">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <sequence length="120" mass="13147" checksum="797C21DBE0E1E3E5" modified="2004-07-05" version="1">MIQRESRLVVVDNSGAKEVLVIGILGGTRRSHVNIGDIVLVTVKSGSGTVKKHDVLKAVIVRTKKGLRRKNGSYIKFDDNAVVLLKEDLNIIGTRIFGPVVRELSDKKFSKIVSLAQLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR13</accession>
    <name>Q6YR13_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpmC</name>
        <name evidence="7" type="ordered locus">PAM_208</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_208"/>
    <dbReference type="EnsemblBacteria" id="BAD04293">
        <property type="protein sequence ID" value="BAD04293"/>
        <property type="gene ID" value="PAM_208"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_208"/>
    <dbReference type="eggNOG" id="COG0255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2220499_0_0_14"/>
    <dbReference type="OrthoDB" id="2049459at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-254-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_L29_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="75"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="106" mass="12031" checksum="8C9FEECCACAF66DC" modified="2004-07-05" version="1">MKTQEILKLKPEELENKVDKLKQELFDLRFQLALGKLTNTAKIKKLKKTIARIKTILTQKSNQQTANTPIFVTSTAKPVLSNQSPTPQPTTPDLDDTVETIKEEQQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-10-11" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR17</accession>
    <name>RS19_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsS</name>
        <name type="ordered locus">PAM_204</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR17"/>
    <dbReference type="SMR" id="Q6YR17"/>
    <dbReference type="STRING" id="262768.PAM_204"/>
    <dbReference type="EnsemblBacteria" id="BAD04289">
        <property type="protein sequence ID" value="BAD04289"/>
        <property type="gene ID" value="PAM_204"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_204"/>
    <dbReference type="eggNOG" id="COG0185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144911_0_1_14"/>
    <dbReference type="OMA" id="FPEMVGH"/>
    <dbReference type="OrthoDB" id="1893906at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-250-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000129869" description="30S ribosomal protein S19">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="93" mass="10690" checksum="5E8B4950817A5294" modified="2004-07-05" version="1">MPRSVKKGPIVASHLLAKIEKQKNLKNKKVIQTWSRSSTITPIFVGHKIAVYNGREHIPVYITENMVGHKLGEFSPTRTYRGHNKKDKKIQKK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-08-03" version="112" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR37</accession>
    <name>GLYA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="1">SHMT</shortName>
            <shortName evidence="1">Serine methylase</shortName>
            <ecNumber evidence="1">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glyA</name>
        <name type="ordered locus">PAM_181</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SHMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR37"/>
    <dbReference type="SMR" id="Q6YR37"/>
    <dbReference type="STRING" id="262768.PAM_181"/>
    <dbReference type="EnsemblBacteria" id="BAD04266">
        <property type="protein sequence ID" value="BAD04266"/>
        <property type="gene ID" value="PAM_181"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_181"/>
    <dbReference type="eggNOG" id="COG0112">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022477_2_1_14"/>
    <dbReference type="OMA" id="SHPAGLI"/>
    <dbReference type="OrthoDB" id="861782at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-222-MON"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0554">One-carbon metabolism</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000113628" description="Serine hydroxymethyltransferase">
        <location>
            <begin position="1"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>(6S)-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="124"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>(6S)-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>(6S)-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
        </ligand>
    </feature>
    <feature type="site" description="Plays an important role in substrate specificity" evidence="1">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <sequence length="416" mass="46327" checksum="6B31FAE437FE2514" modified="2004-07-05" version="1">MNQKLGLKDQDQEIFDLIEQEKIRQKENILLIASENFVSQAVLDAQGSILTNKYAEGYPQARYYNGCKNVDQIEKIAIQRATKLFGAKYANVQPHSGSQANMGAFQALLKPGDKILGLSLMDGGHLTHGHKLSFSGGFYEAHFYNVHPQTEMLDYDEIRKVALKVKPKLIIAGYSAYSKTINFKKFRQIADEVNAYLMADIAHIAGLVACGLHPCPFEANADVVTSTMHKTLRGPRGGLILTNKEEVFKKINRGIFPGIQGGPCIHTIAAKAVAFQEAMMPSFKEYQKQVIKNANTFAKAFQQKGYRIVSGGTDNHLFLIDVKHKNPEFTGSKIANMLEKINIVVNKNTIPFDQEKPFVTSGIRIGTPAMTTVGFRENDFILVADLMDKAINHLDDESYLAQIKQQVLALLSKFNK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-03-18" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR50</accession>
    <name>PYRH_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uridylate kinase</fullName>
            <shortName evidence="1">UK</shortName>
            <ecNumber evidence="1">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Uridine monophosphate kinase</fullName>
            <shortName evidence="1">UMP kinase</shortName>
            <shortName evidence="1">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pyrH</name>
        <name type="ordered locus">PAM_167</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UMP kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR50"/>
    <dbReference type="SMR" id="Q6YR50"/>
    <dbReference type="STRING" id="262768.PAM_167"/>
    <dbReference type="EnsemblBacteria" id="BAD04252">
        <property type="protein sequence ID" value="BAD04252"/>
        <property type="gene ID" value="PAM_167"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_167"/>
    <dbReference type="eggNOG" id="COG0528">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033861_0_0_14"/>
    <dbReference type="OMA" id="PIIVFDM"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-206-MON"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000323910" description="Uridylate kinase">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="133"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <sequence length="241" mass="26612" checksum="70DE3E5904583488" modified="2004-07-05" version="1">MWMHKKILLKLSGESLKGESSYGIDPRTIKKIAWEIKEIKDLGVKIAIIVGAGNLWRGRTGEELGMDRSQADYMGMLGTIMNSLALQDALEQTNTITRVMTAFPVSSVAEPYIRRKAIRHLEKDRVVILGAGAGSPYFSTDTAAALRAAELNIDVILMAKNNIEGVYNKDPKKHQDAVLIKHMKHQQILSQRLAVMDITAASLCLENNIDILVFNMLKKGNIKKVVLKEGNIGTVISSKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR56</accession>
    <name>Q6YR56_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04245">
        <property type="protein sequence ID" value="BAD04245"/>
        <property type="gene ID" value="PAM_160"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_160"/>
    <dbReference type="HOGENOM" id="CLU_1395101_0_0_14"/>
    <dbReference type="OMA" id="FLHINKA"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-199-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="195" mass="23338" checksum="DFBC6076AA17EE52" modified="2004-07-05" version="1">MIKTLIFIYVVNFRIAAFFSPSKPSKESKNNDNKNEQPQIPNVLINNKDFDSNCLINLKLMEMMDKKDKNRSQTDLLELKHKMLETYFNQKIFELEMKQKIKELEEKQQQSKADTIPNNAQTFNSQKNFWDEIPETLKQVLEKLNNIEEMQFEILQDYTKKTYYNSDDRVLYVHPEDFLHINKALGHKKQQQLKN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-06-21" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR64</accession>
    <name>PTH_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name type="ordered locus">PAM_152</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR64"/>
    <dbReference type="SMR" id="Q6YR64"/>
    <dbReference type="STRING" id="262768.PAM_152"/>
    <dbReference type="EnsemblBacteria" id="BAD04237">
        <property type="protein sequence ID" value="BAD04237"/>
        <property type="gene ID" value="PAM_152"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_152"/>
    <dbReference type="eggNOG" id="COG0193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062456_4_1_14"/>
    <dbReference type="OMA" id="SQWLGTR"/>
    <dbReference type="OrthoDB" id="1676462at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-185-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01195">
        <property type="entry name" value="PEPT_TRNA_HYDROL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000187787" description="Peptidyl-tRNA hydrolase">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <sequence length="188" mass="21498" checksum="85AC58063D97B234" modified="2004-07-05" version="1">MKLIVGLGNPGTKFVNTRHNVGFAVVDSFLSQNKYQILKEDKTDHIYQINFNHHQSLLIKPQTYMNLSGEVVKKIINKYRIKIENILVIVDDIYLDEGKLKLKMQGGHGGHNGLRNIIDRLGTKQFKRLKIGVSLDSCMPLDQYLLTPVNASSQKNILKNINIINKIIFNFIQDVDFNILMNGYNSKL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-03-21" modified="2022-08-03" version="115" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR66</accession>
    <name>IF2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">infB</name>
        <name type="ordered locus">PAM_150</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR66"/>
    <dbReference type="SMR" id="Q6YR66"/>
    <dbReference type="STRING" id="262768.PAM_150"/>
    <dbReference type="PRIDE" id="Q6YR66"/>
    <dbReference type="EnsemblBacteria" id="BAD04235">
        <property type="protein sequence ID" value="BAD04235"/>
        <property type="gene ID" value="PAM_150"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_150"/>
    <dbReference type="eggNOG" id="COG0532">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006301_5_1_14"/>
    <dbReference type="OMA" id="NRDNRTG"/>
    <dbReference type="OrthoDB" id="347113at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-182-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0396">Initiation factor</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000228220" description="Translation initiation factor IF-2">
        <location>
            <begin position="1"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="tr-type G">
        <location>
            <begin position="121"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="1">
        <location>
            <begin position="130"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="1">
        <location>
            <begin position="155"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="1">
        <location>
            <begin position="176"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="1">
        <location>
            <begin position="230"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="1">
        <location>
            <begin position="266"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="130"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="176"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="230"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="619" mass="68496" checksum="CBB0D7B1493ECA1B" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-06-07" modified="2022-08-03" version="108" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR76</accession>
    <name>SYE_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="1">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gltX</name>
        <name type="ordered locus">PAM_140</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR76"/>
    <dbReference type="SMR" id="Q6YR76"/>
    <dbReference type="STRING" id="262768.PAM_140"/>
    <dbReference type="EnsemblBacteria" id="BAD04225">
        <property type="protein sequence ID" value="BAD04225"/>
        <property type="gene ID" value="PAM_140"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_140"/>
    <dbReference type="eggNOG" id="COG0008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015768_6_1_14"/>
    <dbReference type="OMA" id="HYINTLP"/>
    <dbReference type="OrthoDB" id="1409413at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-172-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000119617" description="Glutamate--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="1">
        <location>
            <begin position="214"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <sequence length="449" mass="52352" checksum="E3C2C2FD0D9CA4FC" modified="2004-07-05" version="1">MKKIKVRYAPSPTGFLHIGNARTALFNYLFAKQNQGEFIIRIEDTDFSRNVEGGEASQLKNLRWLGIDWSEGPDIQGPFGPYRQSERLAIYQKYAQKLLDQDLAYKEFQEGHTTFAIRFRVPTNQTFAFDDLIRGKLTFQSQEIEDFIILKSNGYPSYNFAVVIDDHLMQISHIFRGEEHITNTPKQIMIYQAFQWHLPQFAHMTLILNENKKKLSKRDANIMQFIEQYEKLGYLPQALFNFLSLLGFSPLSQTEILSPQELINLFDVARLNKAPAMFDKTKLDYLNNQHLRKLLPEVIASFILQKKYLALTTAPTNYKEWMTKFVALFQDRMHYMQQITDFYQLFFQSTPFLSQEATHFLQTNPQTTLILKTFYNVFDVIVFEKDVIANSIKQVTTQNDFAKKTLFMALRIGTTCKMHGPSIALLLELLGKKQVLKNLSYVLEQAQKF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-01-15" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR77</accession>
    <name>RS9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsI</name>
        <name type="ordered locus">PAM_139</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR77"/>
    <dbReference type="SMR" id="Q6YR77"/>
    <dbReference type="STRING" id="262768.PAM_139"/>
    <dbReference type="EnsemblBacteria" id="BAD04224">
        <property type="protein sequence ID" value="BAD04224"/>
        <property type="gene ID" value="PAM_139"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_139"/>
    <dbReference type="eggNOG" id="COG0103">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046483_2_1_14"/>
    <dbReference type="OMA" id="QWKINGR"/>
    <dbReference type="OrthoDB" id="1766414at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-171-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000051276" description="30S ribosomal protein S9">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <sequence length="130" mass="14439" checksum="EA898014034D1D6F" modified="2004-07-05" version="1">MKKVNYFGTGRRKSAVARVILTNGTGKITINTRDFEKYLPLPATRLEMIQPLELTEKREAFDVSVNVNGGGLSAQAGAIRLGIARALIESVPELRAILKKAGLLTRDARCVERKKYGLKKARRAPQFSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR82</accession>
    <name>Q6YR82_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Permease component of an uncharacterized ABC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">PAM_134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_134"/>
    <dbReference type="EnsemblBacteria" id="BAD04219">
        <property type="protein sequence ID" value="BAD04219"/>
        <property type="gene ID" value="PAM_134"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_134"/>
    <dbReference type="eggNOG" id="COG2011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077375_0_2_14"/>
    <dbReference type="OMA" id="MTWSEMQ"/>
    <dbReference type="OrthoDB" id="1220226at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-166-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="23"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="233" mass="26839" checksum="FF565DDD580946AD" modified="2004-07-05" version="1">MENNIFIRLWNVLAKNQLVWNGFKETLKITLIGCFIAFFLGLILGVLLYLFKIQKNYKRYWILNSLMNFFISTPFLILIVLLLKLILIPYFRMGYGFGTALFFLVLAIAPLFARHCEQVFLTTNPELYQTSFSLGATKFQFVTKFLLTETRSDIILKLASLFITSLAYSSVLQIVGHQGIAAVAIDNGYNGHYDFEPFFTRFDLIIVSVLLTFILTQTVYFLGNRIAFALDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR89</accession>
    <name>Q6YR89_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Guanosine polyphosphate pyrophosphohydrolase/synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">spoT</name>
        <name evidence="4" type="ordered locus">PAM_126</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the relA/spoT family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_126"/>
    <dbReference type="EnsemblBacteria" id="BAD04211">
        <property type="protein sequence ID" value="BAD04211"/>
        <property type="gene ID" value="PAM_126"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_126"/>
    <dbReference type="eggNOG" id="COG0317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012300_3_0_14"/>
    <dbReference type="OMA" id="DWISSPK"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="3">
        <location>
            <begin position="458"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="796" mass="92180" checksum="21194B5CEBBE77AC" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-15" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR94</accession>
    <name>CH60_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chaperonin GroEL</fullName>
            <ecNumber evidence="1">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Chaperonin-60</fullName>
            <shortName evidence="1">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">groEL</name>
        <name evidence="1" type="synonym">groL</name>
        <name type="ordered locus">PAM_121</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + a folded polypeptide = ADP + phosphate + an unfolded polypeptide.</text>
            <dbReference type="EC" id="5.6.1.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR94"/>
    <dbReference type="SMR" id="Q6YR94"/>
    <dbReference type="STRING" id="262768.PAM_121"/>
    <dbReference type="EnsemblBacteria" id="BAD04206">
        <property type="protein sequence ID" value="BAD04206"/>
        <property type="gene ID" value="PAM_121"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_121"/>
    <dbReference type="eggNOG" id="COG0459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016503_3_0_14"/>
    <dbReference type="OMA" id="TDTDKME"/>
    <dbReference type="OrthoDB" id="265347at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-153-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000063467" description="Chaperonin GroEL">
        <location>
            <begin position="1"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <sequence length="536" mass="57752" checksum="7150BE7B00356380" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRA2</accession>
    <name>Q6YRA2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04198">
        <property type="protein sequence ID" value="BAD04198"/>
        <property type="gene ID" value="PAM_113"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_113"/>
    <dbReference type="HOGENOM" id="CLU_1804245_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="143" mass="16807" checksum="0449F4F1C0868EFD" modified="2004-07-05" version="1">MKDSFLRMLNANILEIKKRLDALEIEESNQEQSSTESNDDKLNVSIDDLYEIKNDIISRLSPEDQNKIEAQFNESNYFINNIFKPKQKAIKDLLLSLPVYDTEERRQMMEAKTPQEKAQYIKDLIEEFTGATGSKTYFMKERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRB7</accession>
    <name>Q6YRB7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_098"/>
    <dbReference type="EnsemblBacteria" id="BAD04183">
        <property type="protein sequence ID" value="BAD04183"/>
        <property type="gene ID" value="PAM_098"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_098"/>
    <dbReference type="eggNOG" id="COG1464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1804244_0_0_14"/>
    <dbReference type="OMA" id="DDFLQYN"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="143" mass="16488" checksum="9970D4AF76F89C66" modified="2004-07-05" version="1">MEQIIKIASPFQRVLDALVEIKDDFLQYNAKLEILSEQEVQAQYQLSGNDALKQGLIDANIGNNFHTMQGYNQIYKTKEGTLPLTMVSPLFHPKYGLYVHKANTLGLKTLEDVKKHKHLRFLYAPFNELHIAPCDFAQKNRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="111" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRB9</accession>
    <name>Q6YRB9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type transport system, involved in lipoprotein release, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phnL</name>
        <name evidence="6" type="ordered locus">PAM_096</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_096"/>
    <dbReference type="EnsemblBacteria" id="BAD04181">
        <property type="protein sequence ID" value="BAD04181"/>
        <property type="gene ID" value="PAM_096"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_096"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4591">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037418_0_0_14"/>
    <dbReference type="OMA" id="HIYFLGI"/>
    <dbReference type="OrthoDB" id="325456at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-128-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="406"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="499" mass="57101" checksum="21CED4CFB3113042" modified="2004-07-05" version="1">MLKINHLFKKFQNTEVLENVSFQFPQKGLVFIIGKSGSGKSTLLNLIGGLDKPTKGNITVLGRNINEFASFELDAYRNYFLGFVFQEYNLLDNLTVFENIQMACALQSKQVDNWKMQQILKQVELDGLETRYPNQLSGGQKQRVSIARALIKNPKMILADEPTGNLDEKTGQKIFECLKQISKDTLVVIVSHDTQSAYKYADRIIEFADGQIAKDLTQKATKASTDKPQILQNKTYTQEEVANLLKQKNNAMELDFAPTLANENYSSQHQAMHLPLVQTHISKQTALLVTQNILKNNKKLAFKIISTSSNVALFLTLSFLIFFNMFLWLCNLGYVTPESQSKNKTFWLLLTPLLFHIYFLGISFYQMIIHMRNIITLKNKDIGILKSLGVSDRDIHKIFHHLNIKIVIIQFLGIPLFFLIFVLFMVISASLQGKLKYLTTLYSSLKEFVPLYLFLVNIVLFFALAFFYPFFLNHVSIKKQLKKVLKQNPLTIILTVPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRC0</accession>
    <name>Q6YRC0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_095"/>
    <dbReference type="EnsemblBacteria" id="BAD04180">
        <property type="protein sequence ID" value="BAD04180"/>
        <property type="gene ID" value="PAM_095"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_095"/>
    <dbReference type="eggNOG" id="COG1293">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059694_0_0_14"/>
    <dbReference type="OMA" id="NNHKFAT"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-127-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="30"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="306" mass="35334" checksum="5B447788E4BA24EE" modified="2004-07-05" version="1">MWNKVKEVGTAIYNTLPGTKDPENIDAQLLNQIQEEITVIEETKEQIKELTQQDETLKNMLEYDEAYKKAEQQYKEVANNLKENKFQEASNLLKPSPTWWQSFISFFPFVDNQTPQLLKESYKTTLDNLQKVQQVKEDLNKLQNINDVQEYKIIWASIKDKINNFWPSANADVTPTPSDLNSQEEIPAIKNFLNNHKFATKLLGWCLGEKSNDVKTIASNLTNRLAQYIANKAEEKLQNKVEQAKKDVPQKATDAVKGHIFQVITAAVAFTALVITFLYWFIIKKIKKNQIKKPQISKKVTLNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRC8</accession>
    <name>Q6YRC8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_087</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_087"/>
    <dbReference type="EnsemblBacteria" id="BAD04172">
        <property type="protein sequence ID" value="BAD04172"/>
        <property type="gene ID" value="PAM_087"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_087"/>
    <dbReference type="eggNOG" id="COG2868">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140910_1_0_14"/>
    <dbReference type="OMA" id="EYTICNL"/>
    <dbReference type="OrthoDB" id="2065603at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-116-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd16332">
        <property type="entry name" value="Prp-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007422">
        <property type="entry name" value="Peptidase_Prp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036764">
        <property type="entry name" value="Peptidase_Prp_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39178">
        <property type="entry name" value="PTHR39178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04327">
        <property type="entry name" value="Peptidase_Prp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118010">
        <property type="entry name" value="SSF118010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="111" mass="12973" checksum="6B4CEAF1EFE6FC3E" modified="2004-07-05" version="1">MIRYCFYKEQKKITSIQVWGHALYAPKGFDIVCASVSTAIIVTLNALEKLQFQTDITYNLQDKLFELEVKTTQNTVLFTLLDNLEYTICNLAKQYPNNFKKISKIQTRKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRF4</accession>
    <name>Q6YRF4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04146">
        <property type="protein sequence ID" value="BAD04146"/>
        <property type="gene ID" value="PAM_061"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_061"/>
    <dbReference type="HOGENOM" id="CLU_2303038_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-81-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="100" mass="11281" checksum="A640C5C3FD82221E" modified="2004-07-05" version="1">MLNPKDSFLNRLANVRYTANKSNTCFSLCAFLTFALISSYLFVYICNFYFNPCISHDRPFFLGFVFALAIASLIAVVSFSFVVGALSTHLFLLIKHKGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRH0</accession>
    <name>Q6YRH0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_045"/>
    <dbReference type="EnsemblBacteria" id="BAD04130">
        <property type="protein sequence ID" value="BAD04130"/>
        <property type="gene ID" value="PAM_045"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_045"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073330_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="167"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="393" mass="47041" checksum="EA1C9F84893D6A38" modified="2004-07-05" version="1">MGAINNLHKIDMALRSRFSKEIYIGNLKDHEIEGYLKHIIIPYQISYHTFLALKEITQLYQGKNLSNRDLTTIIEEAYKKTAKWAQQNPQTHEFMLPSDIEEVLNLKLKTKPDHQQVKQRRTACENQYAQWREGFNQYLDKPKDETKIECRYTFDSLNGINYYNLRYSQIQTELNNINQQLTKIHQENKIPQLEQELVTLNQTPDKYEQTIKDKNQEIIYIKNNLKTLQAREESLRKELKLVENRRELQKEPSNLVCYIKDRHPFDRWNKKGYTYNHTTLDGFDSASFDKKDDSQLYLYVNFEKQQHKGPGGNYLIVKYKGPKHFLEDDKDYYLGRARVRDANFELTDFRLHFNPVRKTLSLYQDKHNNDKVKEAEMKKTILDGHKNINFRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRH7</accession>
    <name>Q6YRH7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04123">
        <property type="protein sequence ID" value="BAD04123"/>
        <property type="gene ID" value="PAM_038"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_038"/>
    <dbReference type="HOGENOM" id="CLU_2260899_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-54-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="103" mass="11575" checksum="52D76CAB9147AFC0" modified="2004-07-05" version="1">MLERQLESELQAFFAPIQEEVIKKLKAIDQLAEDNKKTIKKTITKFIGLGNAQDFETSAENTDNKDNLDNPTSETSQNQPTPPNDTNVENEKSPLISDNSGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRI1</accession>
    <name>Q6YRI1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04119">
        <property type="protein sequence ID" value="BAD04119"/>
        <property type="gene ID" value="PAM_034"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_034"/>
    <dbReference type="HOGENOM" id="CLU_1502033_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-47-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="179" mass="21315" checksum="B2EAA77FDCED4B87" modified="2004-07-05" version="1">MILSQLNQDKNNLPYDALYSHFFDPKSELSKYYNAASELSELKGINWGSYENDKTKKANDLLDRFSFTKSQFEEFRDEIVKDSYYYGYAPSLKDPKDISIPSLISYLMIANTKPCDLKGFYTNYPWKYSYNINLANWNKDNAKTFISNVLERCWPMTDKLLKHYRYLKEKNILNLYNFK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-12-21" modified="2022-08-03" version="111" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRJ4</accession>
    <name>Y020_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName>Putative ABC transporter ATP-binding protein PAM_020</fullName>
            <ecNumber>7.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">PAM_020</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRJ4"/>
    <dbReference type="SMR" id="Q6YRJ4"/>
    <dbReference type="STRING" id="262768.PAM_020"/>
    <dbReference type="EnsemblBacteria" id="BAD04105">
        <property type="protein sequence ID" value="BAD04105"/>
        <property type="gene ID" value="PAM_020"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_020"/>
    <dbReference type="eggNOG" id="COG1122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_86_7_14"/>
    <dbReference type="OMA" id="YEACPND"/>
    <dbReference type="OrthoDB" id="870493at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-25-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022216">
        <property type="entry name" value="ABC_Co_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12558">
        <property type="entry name" value="DUF3744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000092052" description="Putative ABC transporter ATP-binding protein PAM_020">
        <location>
            <begin position="1"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter 1" evidence="2">
        <location>
            <begin position="6"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter 2" evidence="2">
        <location>
            <begin position="317"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="351"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="588" mass="66174" checksum="4D3C1A730C6C0A89" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="129" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRJ7</accession>
    <name>Q6YRJ7_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable GTP-binding protein EngB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">engB</name>
        <name evidence="10" type="ordered locus">PAM_017</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for normal cell division and for the maintenance of normal septation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_017"/>
    <dbReference type="EnsemblBacteria" id="BAD04102">
        <property type="protein sequence ID" value="BAD04102"/>
        <property type="gene ID" value="PAM_017"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_017"/>
    <dbReference type="eggNOG" id="COG0218">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033732_3_2_14"/>
    <dbReference type="OMA" id="LMMDIRH"/>
    <dbReference type="OrthoDB" id="1746051at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-22-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0717">Septation</keyword>
    <feature type="domain" description="EngB-type G" evidence="9">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="196" mass="22562" checksum="288785C2E0F9A4F9" modified="2004-07-05" version="1">MIKKATFVRSIVHFKDIPLKKQPEIVLMGRSNVGKSTFINALTQRKKLAKISQTPGKTITLNYYDINESFYLIDTPGYGYAKKSKEIQKQLLPMIISFLEQTSHLKAVFQLIDFKVGATQEDDRIHQALLQAGFEVVLLFVKKDKVKKNLVPKQLKMLVNHFPQIKYFFLISSKQQEGLEELKLFLSQLMDPNAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRJ9</accession>
    <name>Q6YRJ9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Translation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sua5</name>
        <name evidence="2" type="ordered locus">PAM_015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_015"/>
    <dbReference type="EnsemblBacteria" id="BAD04100">
        <property type="protein sequence ID" value="BAD04100"/>
        <property type="gene ID" value="PAM_015"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_015"/>
    <dbReference type="eggNOG" id="COG0009">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031397_3_1_14"/>
    <dbReference type="OMA" id="QYWPGAL"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-20-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="185" mass="21027" checksum="1361FE461B7FAA15" modified="2004-07-05" version="1">MKPKDIIIFPTDTVYGMGAKLYDKKGLNCIYQIKKRPLNKSIVVLCASLQQAKKLVQFSPQSLKLALHFWPGPLTLILPTTLKYFSKTKAKTLGIRIPNHPLALEILKKNGPLKTTSVNQSNHPPLNDYQTIFNIYYNKVALIYQNYHPILKISSTIVDLTTFQPVILRQGTITQEEILQILKPL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRK0</accession>
    <name>RF1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptide chain release factor 1</fullName>
            <shortName evidence="1">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">prfA</name>
        <name type="synonym">pam014</name>
        <name type="ordered locus">PAM_014</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRK0"/>
    <dbReference type="SMR" id="Q6YRK0"/>
    <dbReference type="STRING" id="262768.PAM_014"/>
    <dbReference type="PRIDE" id="Q6YRK0"/>
    <dbReference type="EnsemblBacteria" id="BAD04099">
        <property type="protein sequence ID" value="BAD04099"/>
        <property type="gene ID" value="PAM_014"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_014"/>
    <dbReference type="eggNOG" id="COG0216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036856_0_1_14"/>
    <dbReference type="OMA" id="ISDHRVG"/>
    <dbReference type="OrthoDB" id="928964at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-19-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000117250" description="Peptide chain release factor 1">
        <location>
            <begin position="1"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="1">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <sequence length="351" mass="40011" checksum="591F7720D883073C" modified="2004-07-05" version="1">MLDRLKIIKQKYQDLQKLLLNEQNINQKIDILKNLSKLEPTVELFNRYLNLETEFTQIQTILKTQQDQELLLLAHQEKDTILSEKKTTLDQLKILLLPQDPFDKKNVVLEIKGASGGNEANLFAADLLRTYVKYAESKKWKVEILNLNPSIKGGLSSVELLISGKNIYSFLKYESGVHRVQRVPATEAQGRIHTSTAVVLVVPEAEELELKIDWHDIRTDTFNSSGPGGQSVNTTKSAVRLTHIPSGISVACQEGKSQHENKDKAFTILKTRIYNQMLTAKQEEENKHRKNLVGTGERSEKIRTYNYPQNRITDHRIGLTLQKLDIIMEGKLDLVIEPLIHEAQKEQLAQS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRK3</accession>
    <name>RS18_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsR</name>
        <name type="ordered locus">PAM_011</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRK3"/>
    <dbReference type="SMR" id="Q6YRK3"/>
    <dbReference type="STRING" id="262768.PAM_011"/>
    <dbReference type="EnsemblBacteria" id="BAD04096">
        <property type="protein sequence ID" value="BAD04096"/>
        <property type="gene ID" value="PAM_011"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_011"/>
    <dbReference type="eggNOG" id="COG0238">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148710_2_2_14"/>
    <dbReference type="OMA" id="QKKYCRF"/>
    <dbReference type="OrthoDB" id="1940575at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-16-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018275">
        <property type="entry name" value="Ribosomal_S18_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00057">
        <property type="entry name" value="RIBOSOMAL_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000111199" description="30S ribosomal protein S18">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <sequence length="79" mass="9582" checksum="16256EA15C6EF70A" modified="2004-07-05" version="1">MKFNNKKNTFKKRRKVCFFTENKVTKIDFKDIELLQRFITDRGRILSRRVTNTSAKWQRQLAIAIKRARHMALIPFIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRK8</accession>
    <name>Q6YRK8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04091">
        <property type="protein sequence ID" value="BAD04091"/>
        <property type="gene ID" value="PAM_006"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_006"/>
    <dbReference type="HOGENOM" id="CLU_1309100_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="210" mass="25284" checksum="2C074190833A9714" modified="2004-07-05" version="1">MFMYKNNLDTNTNRKAKNVFSKKFLVYVPLIISCITSLLAIDTISYDKNKRNFFTLGLFTRQNTLSVNIFLLLSLNNKFKKSKYYLYLSFVCLINCLIVMFFCLIETKTGTLKINYFFEHKILSLMFIFYYFFRNKSIIKLKKNYVGIIYPLIYFLIMFILIKIDNEKLNPYSREITKYEINEFMLLFYAFLIYINFKLITNIIIEVRKA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRL3</accession>
    <name>DNAA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dnaA</name>
        <name type="ordered locus">PAM_001</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DnaA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRL3"/>
    <dbReference type="SMR" id="Q6YRL3"/>
    <dbReference type="STRING" id="262768.PAM_001"/>
    <dbReference type="EnsemblBacteria" id="BAD04086">
        <property type="protein sequence ID" value="BAD04086"/>
        <property type="gene ID" value="PAM_001"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_001"/>
    <dbReference type="eggNOG" id="COG0593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026910_3_2_14"/>
    <dbReference type="OMA" id="FPAFKIV"/>
    <dbReference type="OrthoDB" id="219876at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-1-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000114225" description="Chromosomal replication initiator protein DnaA">
        <location>
            <begin position="1"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="204"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <sequence length="507" mass="59878" checksum="F340E2B951EDB821" modified="2004-07-05" version="1">MNNYNKIWEIILNELSKIYSDEVFKETFSNIKKINQIEEKIIISVETEFIKNKIYKMYFEKIKKITKLKFEEKIIIEFVSEKNKKNSNFDDEKKHFENLKEKLENENQTYFSKIENNENNDEFQNNKYFETIEKEQIETKTDNDKNVEIENRKISFNKYNYGNTNPKYSFDNFVVGKSNNFAFKIAKKIAEEKKVTTNPLYIFGKAGIGKTHLIQAIGNHILKKTHSSKKVLYVKADGFIEEFTNQLRKAKMEDFNEKYRDIDLLLVDDIQIMAGATRTQMEFFKLFDYLYLNQKQIVITSDKQASELKNIMSRLTSRFEAGLMVDIQSPDFNHRLNILKKKILEFEPQNPLKIKKDVLDLIASSFVNNVREMEGALLRLLNYAQTFGYDIDINIANEALELLIKSKKSVSYDEDVLEKIKSVVSNFFNISVRDLMSKKRQQKYTLPRHIAMYLIKELKDIPYNIVGSFFKRNHSAVFKAYQKIKKNSQSDYELKKSLELILKKINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-02-05" modified="2022-08-03" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A9JQZ9</accession>
    <name>A9JQZ9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAF95566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_756"/>
    <dbReference type="EnsemblBacteria" id="BAF95566">
        <property type="protein sequence ID" value="BAF95566"/>
        <property type="gene ID" value="PAM_756"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_756"/>
    <dbReference type="HOGENOM" id="CLU_2001523_0_0_14"/>
    <dbReference type="OMA" id="NIFFPNK"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-507-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF95566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="111" mass="13125" checksum="BD6808128C611FD6" modified="2008-02-05" version="1">MWIFSIFTIISNFILNYTKGFTAAEIMERRLDGIQTTLFTILIVTGFKPIFKLMTNIIVFIKETISNKKLQILEIKNTKQEHQEQLLLQKLEQIKTVQEKILSQIEQQKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-03-24" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>B9A0T3</accession>
    <name>B9A0T3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <organism evidence="4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4">
        <name>EcOYM</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2002" name="Microbiology" volume="148" first="1389" last="1396">
            <title>Evidence of intermolecular recombination between extrachromosomal DNAs in phytoplasma: a trigger for the biological diversity of phytoplasma?</title>
            <authorList>
                <person name="Nishigawa H."/>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Jung H.Y."/>
                <person name="Kuboyama T."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="11988512"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
            <plasmid evidence="4">EcOYM</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
            <plasmid evidence="4">EcOYM</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB076263">
        <property type="protein sequence ID" value="BAH22133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Plasmid EcOYM"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAH22133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="161" mass="19177" checksum="D956F8CFF63502C9" modified="2009-03-24" version="1">MQIFNYNISAFIDKINDYAIYIITFLKTTFNNIIAIRNVDFSLVNIPNSFGIIWHFILSILYILIFITILVFMGSIFSIFKQIIKWTIYKPIKLFVLGLYYFILLLKYLFTPKSELTQPVQTNNSNLDELKQLNKKISDLEYRLNLQKRQNVIKKDYKKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-03-24" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>B9A0T4</accession>
    <name>B9A0T4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <organism evidence="4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="4">
        <name>EcOYM</name>
    </geneLocation>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2002" name="Microbiology" volume="148" first="1389" last="1396">
            <title>Evidence of intermolecular recombination between extrachromosomal DNAs in phytoplasma: a trigger for the biological diversity of phytoplasma?</title>
            <authorList>
                <person name="Nishigawa H."/>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Jung H.Y."/>
                <person name="Kuboyama T."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="11988512"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
            <plasmid evidence="4">EcOYM</plasmid>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
            <plasmid evidence="4">EcOYM</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB076263">
        <property type="protein sequence ID" value="BAH22134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OMA" id="PPTINYY"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Plasmid EcOYM"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="86"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="116"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="163"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAH22134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="200" mass="23315" checksum="F890F29AA570CD7F" modified="2009-03-24" version="1">MKTNNQKKLKNKIFIIWGLFITGVILVFLIILLLAMNKTQPKTDNQNQPTLTSKTNLQQEQETYNAILRKIKSEVDELTNIKEIVYRPDDKTINYIKILDSQTKKEIKRIVYDGADDENITSIREFNPEGKLIKETFYLLDGKTISSIREFNPEGKQIKKTFYLLDGKTISSIREFNPEGKQIKKTFYNPDGTVKQELIY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-02-16" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>P60402</accession>
    <name>RL2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplB</name>
        <name type="ordered locus">PAM_203</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P60402"/>
    <dbReference type="SMR" id="P60402"/>
    <dbReference type="STRING" id="262768.PAM_203"/>
    <dbReference type="EnsemblBacteria" id="BAD04288">
        <property type="protein sequence ID" value="BAD04288"/>
        <property type="gene ID" value="PAM_203"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_203"/>
    <dbReference type="eggNOG" id="COG0090">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036235_2_1_14"/>
    <dbReference type="OMA" id="SCIELRP"/>
    <dbReference type="OrthoDB" id="961486at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-249-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000129592" description="50S ribosomal protein L2">
        <location>
            <begin position="1"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="221"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="276" mass="30465" checksum="223258EB96564400" modified="2004-02-16" version="1">MAIKKYKPTTNGCRNMSVSAFSEITTQTPEKRLLVSHKDQAGRNNQGKITVRHRGGGVKRKYRLIDFKRNKDNIVGKVATIEYDPNRSANIALIHYLDGEKRYILAPKGLTVGMQIVSGKEADIKVANCLPLMNIPVGTTVHNIELKPGKGGQIARSAGSFCQIISREDKYVLLRLQSGEVRKVLGTCRATIGEIGNESYKLINYGKAGKKRFLGIRPTVRGSAMNPNDHPHGGGEGRAPIGRKSPMTPWGKKARGVKTRDRKKASNALIIRRRTK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-02-16" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>P60455</accession>
    <name>RL3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName>50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">rplC</name>
        <name type="ordered locus">PAM_200</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P60455"/>
    <dbReference type="SMR" id="P60455"/>
    <dbReference type="STRING" id="262768.PAM_200"/>
    <dbReference type="EnsemblBacteria" id="BAD04285">
        <property type="protein sequence ID" value="BAD04285"/>
        <property type="gene ID" value="PAM_200"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_200"/>
    <dbReference type="eggNOG" id="COG0087">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044142_4_2_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000077130" description="50S ribosomal protein L3">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="157" mass="16948" checksum="7B0AE913DB5CDAE2" modified="2004-02-16" version="1">MLGHFKKATTAPKRFIKEINFSADVNSNLANLAVGALITNDLFQVGDLVDVTGTSKGKGFAGSIKRHNQSRGPESHGSRYHRRPGSMGPIKGKLKGKKLPGHMGHETVTIQNLAILSVDTEKNLFLIKGNVPGPNKGFVIIKSAVKKLTKEQTHAKN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-04-26" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>P61067</accession>
    <name>RL4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplD</name>
        <name type="ordered locus">PAM_201</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P61067"/>
    <dbReference type="SMR" id="P61067"/>
    <dbReference type="STRING" id="262768.PAM_201"/>
    <dbReference type="EnsemblBacteria" id="BAD04286">
        <property type="protein sequence ID" value="BAD04286"/>
        <property type="gene ID" value="PAM_201"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_201"/>
    <dbReference type="eggNOG" id="COG0088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041575_5_2_14"/>
    <dbReference type="OMA" id="PQVHILE"/>
    <dbReference type="OrthoDB" id="1572673at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-247-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000129252" description="50S ribosomal protein L4">
        <location>
            <begin position="1"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="207" mass="22857" checksum="136A154D9567AB04" modified="2004-04-26" version="1">MPKINILNQQGDFVSEKVLATTVFDIKPNQQVLYDVVNAQRAAMRQGTHATKTRALVAGGGKKPWRQKGTGRARHGSIRSPLWRGGGVTFGPSPRDYSVKVNQKVRSLALKSALSLQAKNNQLVVVDNINLATHKTKDFQQMLQKLNITSKSLIVVTQMTEQLALASRNLSYITLETASHASVYQILNCKQLVLTAAAVNYFEEVLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-05-10" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>P61337</accession>
    <name>EFTS_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor Ts</fullName>
            <shortName evidence="1">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tsf</name>
        <name type="ordered locus">PAM_166</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04251" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04251.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P61337"/>
    <dbReference type="SMR" id="P61337"/>
    <dbReference type="STRING" id="262768.PAM_166"/>
    <dbReference type="EnsemblBacteria" id="BAD04251">
        <property type="protein sequence ID" value="BAD04251"/>
        <property type="gene ID" value="PAM_166"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_166"/>
    <dbReference type="eggNOG" id="COG0264">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047155_0_2_14"/>
    <dbReference type="OMA" id="DAGMMDC"/>
    <dbReference type="OrthoDB" id="1405357at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-205-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0251">Elongation factor</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000161166" description="Elongation factor Ts">
        <location>
            <begin position="1"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="1">
        <location>
            <begin position="79"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="274" mass="31019" checksum="8A8F962270A4D8AB" modified="2005-03-01" version="2">MKITAEMIKDLRQKTHAGMKECHKALQQTEGNIEKAIVFLREKGIIKAAQKQGRATSEGITNIVFDGNNAFLYEINSETDFVSKNEHFQQLVKVLGEIILKNQLSNAKDLLAFNYQNKTVQELLLEKTSVLGENITLKRVLKVTKKPQESFGTYKHQGGRISVLVVLKNDCPSVSEDIAMHIAASKPQFLTPDKVDPTFLAEEKKILHKQTAKELSDKPAQMIEKIVENRLGKMLKDMCLSEQPFVKNADQKVKDYLKANNTDVVSYVRWEMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="116" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPH5</accession>
    <name>Q6YPH5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type sugar transport system, ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">malK</name>
        <name evidence="5" type="ordered locus">PAM_752</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_752"/>
    <dbReference type="EnsemblBacteria" id="BAD04837">
        <property type="protein sequence ID" value="BAD04837"/>
        <property type="gene ID" value="PAM_752"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_752"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_14"/>
    <dbReference type="OMA" id="IDDLHHK"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="347" mass="39100" checksum="E8D6FDAAAB6826A9" modified="2004-07-05" version="1">MGIKLEQVSKIFIDKQTKKETYAVKKIDINIPKGKLVSLLGPSGCGKSTTLYMIAGLHPISAGKIFFGDKDVTNLPIEKRGIGLVFQNYALYPHMTVRQNISFPLENLKFARDIIVQKVEEIAKLVGIADHLDKKPQQLSGGQQQRVAIARALVKEPQVLLLDEPLSNLDAGLRLKTREEIRRIQRKTGITAIFVTHDQEEAMSISDEICLMNKGQIQQKGAPQEVYANPNNLFVAKFLGNPLISIFEGKITFGKVTIGDSLLFDFSSNKTLKNLNQEIYVAIRPEGYWFDTNGNFEIEPLFLENVGRNLMMLARHPQAVKKTFHLVFDEKSKDIIFSPRICCQEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-12-02" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPH7</accession>
    <name>Q6YPH7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ugpE</name>
        <name evidence="6" type="ordered locus">PAM_750</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_750"/>
    <dbReference type="EnsemblBacteria" id="BAD04835">
        <property type="protein sequence ID" value="BAD04835"/>
        <property type="gene ID" value="PAM_750"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_750"/>
    <dbReference type="eggNOG" id="COG0395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_1_1_14"/>
    <dbReference type="OMA" id="IAFFIAW"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="52"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="264" mass="30139" checksum="742F684011B4363B" modified="2004-07-05" version="1">MSVFALFLAIPFYWMLNLALQDNPACPSFFPKDLTWNNFSFLFTRYSLFLTFFKTLAVVFISTVLGIFVSVITAFALSILEFRTKKIILGVFLITTMITTESMFLTNYQTVARLGFVDSGQGTRVFSGIYLAMILPFLINVFHIFLLIQNIKKIPKELYLSAKVDGSSDWKFLYKILTPLLRDNIINIIIFRAVAAWNAYLWPELVGGKLLTNVIRNIFDSEKNQNLVNQQMAATVLMTLPLVLLFIFCKRYVLEGKLNSGIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPH9</accession>
    <name>Q6YPH9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exopolyphosphatase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_748"/>
    <dbReference type="EnsemblBacteria" id="BAD04833">
        <property type="protein sequence ID" value="BAD04833"/>
        <property type="gene ID" value="PAM_748"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_748"/>
    <dbReference type="eggNOG" id="COG0618">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039720_1_0_14"/>
    <dbReference type="OMA" id="CTRWVES"/>
    <dbReference type="OrthoDB" id="1040743at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-903-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="1">
        <location>
            <begin position="13"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="2">
        <location>
            <begin position="186"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="322" mass="36523" checksum="90CF202F16D7476F" modified="2004-07-05" version="1">MKIIYNKIKAFETIIIHGHINPDGDCYGAQLGLKDAITATFPQKKVYAVGQQNHSLSFVGVMDEVCDSLYQSALAIVVDCGQENKISDQRFKLAKDTIRIDHHLLMDNYCNYQWVDANYSSCSQMIFEFKEKCNMKLTHKGALAMYVGMVTDTGNFCFDRVDQNTLKAAASLLAFDLDVSQIFFHLNKETLTLFQYKAYIYQNVVTSQGFAYVFISQETLKKFNLHIDVAASLVNILGHLENHPVWAFFLEQPDLTIRARIRSRGPEINSIARQFKGGGHLRACGATLNNNQEMTFFIAQIKDSIKAFETKSQDKNPKLIKN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-01-15" modified="2022-08-03" version="113" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPI0</accession>
    <name>MNME_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA modification GTPase MnmE</fullName>
            <ecNumber evidence="1">3.6.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mnmE</name>
        <name evidence="1" type="synonym">trmE</name>
        <name type="ordered locus">PAM_747</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="1">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPI0"/>
    <dbReference type="SMR" id="Q6YPI0"/>
    <dbReference type="STRING" id="262768.PAM_747"/>
    <dbReference type="EnsemblBacteria" id="BAD04832">
        <property type="protein sequence ID" value="BAD04832"/>
        <property type="gene ID" value="PAM_747"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_747"/>
    <dbReference type="eggNOG" id="COG0486">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019624_4_1_14"/>
    <dbReference type="OMA" id="CEIQCHG"/>
    <dbReference type="OrthoDB" id="263682at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-902-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00379">
        <property type="entry name" value="GTPase_MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004520">
        <property type="entry name" value="GTPase_MnmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00450">
        <property type="entry name" value="mnmE_trmE_thdF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51709">
        <property type="entry name" value="G_TRME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0630">Potassium</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000048843" description="tRNA modification GTPase MnmE">
        <location>
            <begin position="1"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="TrmE-type G">
        <location>
            <begin position="219"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="229"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="248"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="273"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="333"/>
            <end position="336"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00379"/>
        </source>
    </evidence>
    <sequence length="460" mass="51514" checksum="A393F393CE7E8BE4" modified="2004-07-05" version="1">MFFDTIAAISTPLGTGGVSVIRVSGNNSIAEINKIFKGKDLTKTKTHTITHGFILNKNQTILDEVLISVFKTPNSFTGENVVEINAHGGILITQMVLERVLSLDIRLAFPGEFSQRAYLNGKMDLIQAESIMDLIHATNENAIKIAHSGLQKYTSQLVTSLRDQILNLIAQIEVNIDYPEYDDIPQITQQKIALEVKSLIKQLENILNHSHKNRYLKEGIKTLIVGRPNVGKSSLLNAFLNETKAIVSDISGTTRDFVEAYFNCQGITLHLIDTAGIRKTDDPIEKIGILRTEKMLLQAELILLVLDQNNHLQEEDIQLLQLTKNHPRIIIGNKADLKSDKLISSLSNNSSQLAPQEIISVSSLDKTGFLELQQTILKKFQLNDIQPKDFNYFSNARHINQIQIALRSFQDLQQALLQSMPIDIYSIDLTKAYQALGQIIGDNQENSLIKELFSKFCLGK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-04-26" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPJ4</accession>
    <name>RSMA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="1">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmA</name>
        <name evidence="1" type="synonym">ksgA</name>
        <name type="ordered locus">PAM_731</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPJ4"/>
    <dbReference type="SMR" id="Q6YPJ4"/>
    <dbReference type="STRING" id="262768.PAM_731"/>
    <dbReference type="EnsemblBacteria" id="BAD04816">
        <property type="protein sequence ID" value="BAD04816"/>
        <property type="gene ID" value="PAM_731"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_731"/>
    <dbReference type="eggNOG" id="COG0030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041220_0_0_14"/>
    <dbReference type="OMA" id="KEEEPYF"/>
    <dbReference type="OrthoDB" id="2030110at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-886-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000101576" description="Ribosomal RNA small subunit methyltransferase A">
        <location>
            <begin position="1"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <sequence length="268" mass="31099" checksum="7CE8EB091AF1A44B" modified="2004-07-05" version="1">MHHTTKKKYGQNFLTDVNLLNKIVTKASITDKNVLEIGPGKGALTKIIVPQAKHVLAYEIDATLKPFLNFENHNNVNIIYDDFLKRDLLKDFDHYFSPNSQLSLIGNLPYYITSPILFKIIDTPQINDATIMIQKEVGMRLLAQPNNKNYNALSVIIQFLFSIEKIQEVKRHMFFPAPKVDSIVIKLTKNNNICPTFLQQFIKFVKASFKQKRKTLLNNLSCQFLLSKETIIPFFLQHHIPLQIRAEQVTLETFQKLTVKWFIFFNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPJ5</accession>
    <name>Q6YPJ5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD superfamily phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_730"/>
    <dbReference type="EnsemblBacteria" id="BAD04815">
        <property type="protein sequence ID" value="BAD04815"/>
        <property type="gene ID" value="PAM_730"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_730"/>
    <dbReference type="eggNOG" id="COG1078">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026821_0_0_14"/>
    <dbReference type="OMA" id="FSHAMEH"/>
    <dbReference type="OrthoDB" id="370035at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-885-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="64"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="417" mass="49246" checksum="AE4E009D6620521A" modified="2004-07-05" version="1">MQTTNPSFKKFLRSEVFRDPIYGYIYLEYELIEKLINTSVFQRLRRIKQLSGANIVFHGAEHSRFTHSLGVYELARRFLKITNIKKHFSETQKLILLVSSLLHDIGHGAYSHSFETLFDVNHETQSARIIKNNKEIGALLDQISPDFKNDVASVIEKTKKFPLIEQILTSQIDIDRLDYLERDSYFTGATYGHIDLERLMRSMIIEPHPSKNNEKCIAFRQSGVFAIENYLINRYHMFWQVYYHPKVRAYSTILEKICKRLCDLLQNNYPVDPYIQPFYNFVNNQTDLDKYLAIDDYYMNGLILHLKNSKDTILKNLCNDFLNRRIWHILDDKDQNQEQIEHIKQQYHSQNPDYIKYYTSSNAAFQNAYSESKPKFETKILIKSQGGLKSLKEESPIIKSLIKSSPKQDNKFFYRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPJ6</accession>
    <name>Q6YPJ6_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Phosphate propanoyltransferase</fullName>
            <ecNumber evidence="3 6">2.3.1.222</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">PAM_729</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>phosphate + propanoyl-CoA = CoA + propanoyl phosphate</text>
            <dbReference type="Rhea" id="RHEA:28046"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:58933"/>
            <dbReference type="EC" id="2.3.1.222"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Polyol metabolism; 1,2-propanediol degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PduL family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.222" evidence="3 6"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_729"/>
    <dbReference type="EnsemblBacteria" id="BAD04814">
        <property type="protein sequence ID" value="BAD04814"/>
        <property type="gene ID" value="PAM_729"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_729"/>
    <dbReference type="eggNOG" id="COG4869">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080676_1_0_14"/>
    <dbReference type="OMA" id="EMRERPI"/>
    <dbReference type="UniPathway" id="UPA00621"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051144">
        <property type="term" value="P:propanediol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008300">
        <property type="entry name" value="PTAC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39453">
        <property type="entry name" value="PTHR39453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06130">
        <property type="entry name" value="PTAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010130">
        <property type="entry name" value="PduL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR010130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="198" mass="21913" checksum="665B1B3E5D43C0E3" modified="2004-07-05" version="1">MQTMEANMYHIPIGISGRHTHLSQETLDILFGQKNYQLTFFKPLKQTGQFAAQEKIDVMSPSGKILPQVRILGPTRPFDQVEISQSDALRHGFTAPVRSSGDIKGSGKATLIGLKGQVDIEEGVIIANRHIHLSTQDAKNFGITDKQMVSIEIEGTKPGILKQVLCRVHHDFKLECHLDTDDGSAFLLKNGDTVKLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPJ8</accession>
    <name>Q6YPJ8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hflB</name>
        <name evidence="4" type="ordered locus">PAM_727</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_727"/>
    <dbReference type="EnsemblBacteria" id="BAD04812">
        <property type="protein sequence ID" value="BAD04812"/>
        <property type="gene ID" value="PAM_727"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_727"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-881-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="282"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="457" mass="52975" checksum="D3D7A8424039E158" modified="2004-07-05" version="1">MTLNKKIYLSLIGLLSLGFLVLLIFGITRSRSTTKTPSLTQKPPSTQQQEIDNQIKLEQAKIQELQQQDQTLKTQIDENVKTLTDIITKIKTLQTELTNNTQLPPNMKTQKQQQLTELKTQQQTQQTIVNNLIEQRKALNQNQKEKQEELEKLAQEKAQLQTQENLQQQIFQLNQALNYVEANQKRIEELKTQKEYQKNQTELKNFKDFQLFLTDQKLSFEKQKKNLTTQLNHLKENKPLPYTKKQVTFKDVYGMESEKEELEDLLTYFRTNQSLINFDQVRPKGYLLYGPPGTGKTFLIKALCGEANVHFINLIPSKFRQKYIGEGEKEVEKVWQEAENHDKTIIFIDEIEGLENRNDSNISSGGVNVINTLLDKLDGFNSSNKKIVLMGSTNNLHKIDTALRSRFSKEIYIGHLKDSEIEGYLKHIIVPYQISYHTFLALKDITQLCQGVFVGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPJ9</accession>
    <name>Q6YPJ9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_726</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_726"/>
    <dbReference type="EnsemblBacteria" id="BAD04811">
        <property type="protein sequence ID" value="BAD04811"/>
        <property type="gene ID" value="PAM_726"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_726"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-879-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="109" mass="12733" checksum="4E870947A636E5FF" modified="2004-07-05" version="1">MLNKVQLIGRLSHDLEKQYINSNNEQIPKIDFQLAVNLKEITQFIPCVVFRKQADNMKKYLHKGSKIYLEGILSIQKYTNNEGQTKINTKVILQNVIFLDNKPQENLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPK7</accession>
    <name>Q6YPK7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Phosphatidylglycerophosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">PAM_718</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="10">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_718"/>
    <dbReference type="EnsemblBacteria" id="BAD04803">
        <property type="protein sequence ID" value="BAD04803"/>
        <property type="gene ID" value="PAM_718"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_718"/>
    <dbReference type="eggNOG" id="COG0558">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051314_2_1_14"/>
    <dbReference type="OMA" id="WSMVYYL"/>
    <dbReference type="OrthoDB" id="1702107at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-871-MON"/>
    <dbReference type="UniPathway" id="UPA00997"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00560">
        <property type="entry name" value="pgsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="219" mass="24798" checksum="50EFCDA880ED338A" modified="2004-07-05" version="1">MFPLLANLITVFRIVLVFVLLPLMCVSESEPEFANVLTFQIIFIVAAITDYLDGYIAKKYQQQTVFGKFFDPIADKLLVIITLFYICQCRLSATQGTFLFADTQMPKKFFTAVIMIIVIREFLVTGIRLVASNKEGVVISASFWGKAKTVFTFVAIICLFFGLYTSSTFACDANLKKWFGYLSNIGDICLLVSVVLTIVSGFDYFFKNYKIIRKNFAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPL6</accession>
    <name>Q6YPL6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_709</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04794">
        <property type="protein sequence ID" value="BAD04794"/>
        <property type="gene ID" value="PAM_709"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_709"/>
    <dbReference type="HOGENOM" id="CLU_2826911_0_0_14"/>
    <dbReference type="OrthoDB" id="2211174at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-864-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="66" mass="8114" checksum="C8492AF77F0FB9B3" modified="2004-07-05" version="1">MPIFDIDLKCYKDKVPYLNFKYNQNDFINFMKKLNIPKEDKKYDIRTFIIYNLTNNIVDPENKYVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPL7</accession>
    <name>Q6YPL7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04793">
        <property type="protein sequence ID" value="BAD04793"/>
        <property type="gene ID" value="PAM_708"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_708"/>
    <dbReference type="HOGENOM" id="CLU_2753940_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-862-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="70" mass="8289" checksum="E54FD627C9DC64C3" modified="2004-07-05" version="1">MDAKHKIKIKEENQKLENKNELAFNSFFEKPPNIKEQIINSEMPKQNPSQLKKYNINKITVAPYLIYPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPL8</accession>
    <name>Q6YPL8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04792">
        <property type="protein sequence ID" value="BAD04792"/>
        <property type="gene ID" value="PAM_707"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_707"/>
    <dbReference type="HOGENOM" id="CLU_1282153_0_0_14"/>
    <dbReference type="OMA" id="QQQMSFM"/>
    <dbReference type="OrthoDB" id="1834904at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-861-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="127"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="215" mass="25606" checksum="624071B56450DDFE" modified="2004-07-05" version="1">MTRNKKYILITTIFLILIGITTFYFFVTPQLFTSDAMLLKTSSQNNNKTEINNKIEVSQENFNKRLKYITNNELKELPKILPIKAKEKELRKQYQQQQMSFMSKDEKESYENILKINSKMDDISLSSKKINKDIKVLERQYEAANEQEKRKIEDKMNRIVDTLQQLSQQNKQLENDQTLAITRHNNLFQNLQTKNKFSQIDIPPLPKCFKRNIQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPM7</accession>
    <name>Q6YPM7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">himA</name>
        <name evidence="2" type="ordered locus">PAM_534</name>
        <name evidence="3" type="ordered locus">PAM_698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_534"/>
    <dbReference type="EnsemblBacteria" id="BAD04619">
        <property type="protein sequence ID" value="BAD04619"/>
        <property type="gene ID" value="PAM_534"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04783">
        <property type="protein sequence ID" value="BAD04783"/>
        <property type="gene ID" value="PAM_698"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_534"/>
    <dbReference type="KEGG" id="poy:PAM_698"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_3_14"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-640-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-850-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="110" mass="12522" checksum="5973576B4EF2D0B5" modified="2004-07-05" version="1">MTKKELIKSIAEKNKTSITQTEEFYNSFENAIIKAITNNAEVVLSSKLGKFILKTRKAHLTPETKFIINKRTGKKNAQRTGKNLKIPSKTVVTFKLSKTIKDKVKELKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPN3</accession>
    <name>Q6YPN3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_692"/>
    <dbReference type="EnsemblBacteria" id="BAD04777">
        <property type="protein sequence ID" value="BAD04777"/>
        <property type="gene ID" value="PAM_692"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_692"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_483816_0_0_14"/>
    <dbReference type="OMA" id="ASKWDTY"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-843-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="441"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="563" mass="64431" checksum="4B6BF6C3737AA860" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPP9</accession>
    <name>Q6YPP9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">5'-3' exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">exo</name>
        <name evidence="4" type="ordered locus">PAM_676</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_676"/>
    <dbReference type="EnsemblBacteria" id="BAD04761">
        <property type="protein sequence ID" value="BAD04761"/>
        <property type="gene ID" value="PAM_676"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_676"/>
    <dbReference type="eggNOG" id="COG0258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004675_1_5_14"/>
    <dbReference type="OMA" id="WRVDLIP"/>
    <dbReference type="OrthoDB" id="1220182at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-825-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038969">
        <property type="entry name" value="FEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646">
        <property type="entry name" value="PTHR42646"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="53EXOc" evidence="3">
        <location>
            <begin position="2"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="322" mass="37107" checksum="27A5C847A804F4FE" modified="2004-07-05" version="1">MKHLVLVDGNSLLFRAYHATASKYKPLLQNKKGIYTNALLSFIRMFEKILEETKGYILVAFDTHKPTKRHQLYDAYKQGRPETPSALISQIPLIKQYLDLIGVKYHAQDEYEADDIIGTLAKEASNQNKTVSIYSSDQDLLQLVDEKITVCLLKKGLREIKCYKPPTLFEEYGLKEYQMIDYKSLIGDPSDNIKGVLGIGPKTAQKLLQEYDSLDNLMQNLDNIKPILKIKIQNSQADLELSKTLTAIDLKVPLPFDFMQTEIQIRLAQNLKNFYEEMDFRRLAITKYARIEIEPNTTNTNANYNNKEVSRKSKEVQEVEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPQ9</accession>
    <name>Q6YPQ9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tra5</name>
        <name evidence="2" type="ordered locus">PAM_666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_666"/>
    <dbReference type="EnsemblBacteria" id="BAD04751">
        <property type="protein sequence ID" value="BAD04751"/>
        <property type="gene ID" value="PAM_666"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_666"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_4_3_14"/>
    <dbReference type="OMA" id="IAHYNER"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="155"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="316" mass="37908" checksum="44914EC050A1D53F" modified="2004-07-05" version="1">MVLIMQKLKKKIKLLQNMISHIQTINKKIVFQLVKQFVKDLNLTTILKTIRINRSTYYYWLKIEKKLKLKETKYFLQQQRIQTLCLQHEYFYGHRKITDLYQEIFNEFITKKKVYLIMKENNICCKLRPKKNKYYYKNLKSNLKVIPNLINQNFTTSQPMQKLFTDVTYFPTPQGFIYFSCIIDSFNNQIIAFHTSNRQNKELILNTIKKIPTLKNPCIIHSDQGKVYQSLKVQKKLTKKGFLISMSHKANPRDNAVIENLFGQMKSILFNQHPFLFQKTSTKIKKIINQFPSFWNNKWLLTKLNNLSPLQYLQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPS2</accession>
    <name>Q6YPS2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">PAM_653</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_653"/>
    <dbReference type="EnsemblBacteria" id="BAD04738">
        <property type="protein sequence ID" value="BAD04738"/>
        <property type="gene ID" value="PAM_653"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_653"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="272"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="105"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="546"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="617" mass="72155" checksum="EC31D08DFE1DB162" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPS9</accession>
    <name>Q6YPS9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_389</name>
        <name evidence="2" type="ordered locus">PAM_646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">Onion yellows</strain>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_389"/>
    <dbReference type="EnsemblBacteria" id="BAD04474">
        <property type="protein sequence ID" value="BAD04474"/>
        <property type="gene ID" value="PAM_389"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04731">
        <property type="protein sequence ID" value="BAD04731"/>
        <property type="gene ID" value="PAM_646"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_389"/>
    <dbReference type="KEGG" id="poy:PAM_646"/>
    <dbReference type="eggNOG" id="ENOG5033PU3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1239554_0_0_14"/>
    <dbReference type="OMA" id="FFNIQQF"/>
    <dbReference type="OrthoDB" id="6159at544448"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-465-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-786-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="207" mass="24874" checksum="A04DF8D277F6572D" modified="2004-07-05" version="1">MLNNQDFFNIQQFNTNIQTVEILKCFFNKDTFNLSINEYMKTNYQQLNHYFNQNNINSQSQKVIRGKINEYLILLYFQNQGIIHLYPQAYLFFIPDIKFDLVLFTKNKRIIAFNFKTCLRDRYKQAMVEGQQLKKLDTRFEFYLLTNNEPETQRLNHKINQGKVQGINQVINLFSNSANNFLQNLITRQFIPFSNINIIKKEKKELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPU2</accession>
    <name>Q6YPU2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribonuclease J</fullName>
            <shortName evidence="9">RNase J</shortName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rnj</name>
        <name evidence="12" type="ordered locus">PAM_633</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, may be a subunit of the RNA degradosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_633"/>
    <dbReference type="EnsemblBacteria" id="BAD04718">
        <property type="protein sequence ID" value="BAD04718"/>
        <property type="gene ID" value="PAM_633"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_633"/>
    <dbReference type="eggNOG" id="COG0595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008727_3_1_14"/>
    <dbReference type="OMA" id="KNTCVFE"/>
    <dbReference type="OrthoDB" id="580619at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-771-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01491">
        <property type="entry name" value="RNase_J_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004613">
        <property type="entry name" value="RNase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030854">
        <property type="entry name" value="RNase_J_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041636">
        <property type="entry name" value="RNase_J_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001587">
        <property type="entry name" value="RNase_J_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17770">
        <property type="entry name" value="RNase_J_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004803">
        <property type="entry name" value="RnjA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00649">
        <property type="entry name" value="MG423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01292">
        <property type="entry name" value="UPF0036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="11">
        <location>
            <begin position="27"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 10">
        <location>
            <begin position="372"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR004803-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="563" mass="63103" checksum="F239670776D48A93" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-12-12" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPW4</accession>
    <name>PYRG_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CTP synthase</fullName>
            <ecNumber evidence="1">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="1">CTP synthetase</shortName>
            <shortName evidence="1">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pyrG</name>
        <name type="ordered locus">PAM_611</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTP synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPW4"/>
    <dbReference type="SMR" id="Q6YPW4"/>
    <dbReference type="STRING" id="262768.PAM_611"/>
    <dbReference type="EnsemblBacteria" id="BAD04696">
        <property type="protein sequence ID" value="BAD04696"/>
        <property type="gene ID" value="PAM_611"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_611"/>
    <dbReference type="eggNOG" id="COG0504">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011675_5_0_14"/>
    <dbReference type="OMA" id="EFNNAYR"/>
    <dbReference type="OrthoDB" id="783657at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-737-MON"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
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        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000266168" description="CTP synthase">
        <location>
            <begin position="1"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-1" evidence="1">
        <location>
            <begin position="306"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="1">
        <location>
            <begin position="1"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="1">
        <location>
            <position position="388"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="512"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="514"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="20"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="154"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="194"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
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    <feature type="binding site" evidence="1">
        <location>
            <begin position="194"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
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    <feature type="binding site" evidence="1">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="389"/>
            <end position="392"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <sequence length="540" mass="61230" checksum="A5EF8A6F67AB2492" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPX5</accession>
    <name>Q6YPX5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyruvate dehydrogenase E1 component subunit alpha</fullName>
            <ecNumber evidence="3">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">acoA</name>
        <name evidence="3" type="synonym">pdhA</name>
        <name evidence="5" type="ordered locus">PAM_600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_600"/>
    <dbReference type="EnsemblBacteria" id="BAD04685">
        <property type="protein sequence ID" value="BAD04685"/>
        <property type="gene ID" value="PAM_600"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_600"/>
    <dbReference type="eggNOG" id="COG1071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029393_1_0_14"/>
    <dbReference type="OMA" id="GMFRGVN"/>
    <dbReference type="OrthoDB" id="1248201at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-724-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017596">
        <property type="entry name" value="PdhA/BkdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF41">
        <property type="entry name" value="PTHR11516:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03181">
        <property type="entry name" value="PDH_E1_alph_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="E1_dh" evidence="4">
        <location>
            <begin position="41"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="363" mass="40891" checksum="83F451FB2DBE5905" modified="2004-07-05" version="1">MLTNVYDPLKGKQFQILDENGNLVQPELEPKLSKDVLLKMYKTMVLGRQADLAALKYQRQGRMGNYLLNSGQEASQVGVAAALEPQDWVSPYYRDAGIFLYRGVSLEQFYLYWYGNEKGSQLDPKLRILPANIIIGSSVNLGAGLALASKMQNKKEVTIATIGDGGTAHEEFNAGLNYAAVFGVPLVVFIQNNQYSISNPRNKVSKAKTLAQKCYACGIPGMQVDGNDILAVYVAAQEAFNEARKGNGPTLIENVSYRLEAHSTNDNASVYRSKEEELEWRKKDPIVRFQKYLMNKGYLTQKQVEQFEKEAQEEVVLAHQKVEQTGNNIDIKDIFAYTYEKMTPQLEEQYEECKAFFNTKEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="125" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPZ0</accession>
    <name>Q6YPZ0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium-transporting ATPase, P-type 1</fullName>
            <ecNumber evidence="5">7.2.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Mg(2+) transport ATPase, P-type 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">mgtA</name>
        <name evidence="17" type="ordered locus">PAM_585</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Mediates magnesium influx to the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + Mg(2+)(out) = ADP + H(+) + Mg(2+)(in) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10260"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.14" evidence="5"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_585"/>
    <dbReference type="EnsemblBacteria" id="BAD04670">
        <property type="protein sequence ID" value="BAD04670"/>
        <property type="gene ID" value="PAM_585"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_585"/>
    <dbReference type="eggNOG" id="COG0474">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_6_3_14"/>
    <dbReference type="OMA" id="WTQEMVI"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015444">
        <property type="term" value="F:P-type magnesium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02077">
        <property type="entry name" value="P-type_ATPase_Mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006415">
        <property type="entry name" value="P-type_ATPase_IIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01836">
        <property type="entry name" value="MGATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01524">
        <property type="entry name" value="ATPase-IIIB_Mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="713"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="755"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="790"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="821"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="862"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="16">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_C" evidence="15">
        <location>
            <begin position="710"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="BAD04670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="892" mass="100089" checksum="39DA54724DECAF31" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPZ5</accession>
    <name>Q6YPZ5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">folK</name>
        <name evidence="10" type="ordered locus">PAM_580</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="2"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_580"/>
    <dbReference type="EnsemblBacteria" id="BAD04665">
        <property type="protein sequence ID" value="BAD04665"/>
        <property type="gene ID" value="PAM_580"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_580"/>
    <dbReference type="eggNOG" id="COG0801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097916_0_0_14"/>
    <dbReference type="OMA" id="QVILRQN"/>
    <dbReference type="OrthoDB" id="1953248at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-703-MON"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="HPPK" evidence="9">
        <location>
            <begin position="10"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="171" mass="19542" checksum="42046B66AD883A7D" modified="2004-07-05" version="1">MKLNNNVAAIGLGSNLGAKKNNLQTALKMINLHPQCEVLKVSPLYATLPWGKTDQPLFLNAAALIKTFLPPLLFLDFLLSVEMKLKRKRLELWGPRTIDLDIFFLGNHTCKTPKLTIPHPYMLERIFVLAPLADILPNQIIQTKTILEWKNQLDQNAVKIIENNQWYQPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ02</accession>
    <name>Q6YQ02_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_573</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_573"/>
    <dbReference type="EnsemblBacteria" id="BAD04658">
        <property type="protein sequence ID" value="BAD04658"/>
        <property type="gene ID" value="PAM_573"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_573"/>
    <dbReference type="HOGENOM" id="CLU_1319854_0_0_14"/>
    <dbReference type="OrthoDB" id="1617013at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-692-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="208" mass="24765" checksum="73D264830E273E9A" modified="2004-07-05" version="1">MKNDTSQEIRIGGWNTKTTPNDLTQIKNFLKILKEDLINLNIISHSKKKNTYQEADYRPKNQTLFVDPQILEEMKQTKITLINDNFSSSNGKLLLSDLTPLKSQNNPLKYLYPLFQINYQNETKNRIKELIGKIDVNKLETLQLYQLDPQKLDKYHKPMKTNYKKGLNIIYYLKEDLKYIQSFLIKDKQGYRVKKLHPMYKYLIKKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ35</accession>
    <name>Q6YQ35_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_540"/>
    <dbReference type="EnsemblBacteria" id="BAD04625">
        <property type="protein sequence ID" value="BAD04625"/>
        <property type="gene ID" value="PAM_540"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_540"/>
    <dbReference type="HOGENOM" id="CLU_1936972_0_0_14"/>
    <dbReference type="OMA" id="FNARNNN"/>
    <dbReference type="OrthoDB" id="1997966at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-646-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="125" mass="14611" checksum="7EAF621163401B59" modified="2004-07-05" version="1">MIKLQNQFKIINICLFIFLGLFLINNNYYVMAMNNGHISQNNGHDNDHTNFQNQARILQNLNFQQAGIVQQIFNARNNNSSEEVINNLMRQNIELSSRIAAQQIILQNAMPQQNDQNQQNNPRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ52</accession>
    <name>Q6YQ52_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replicative DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dnaB</name>
        <name evidence="2" type="ordered locus">PAM_523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_523"/>
    <dbReference type="EnsemblBacteria" id="BAD04608">
        <property type="protein sequence ID" value="BAD04608"/>
        <property type="gene ID" value="PAM_523"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_523"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_546093_0_0_14"/>
    <dbReference type="OrthoDB" id="284055at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-627-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="1">
        <location>
            <begin position="192"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="499" mass="58892" checksum="1AB7A870FA76523B" modified="2004-07-05" version="1">MNHLTNEQQALIQIINYIEQGQWEKLNLYCQIINPKYLQEAHHQKIFNALRYLFLERTISHPWDKITTKPIIIKELLAYLQTHFPQDHFTKESLFFLNNDFSKENNLNFLANLKHTYTQEKLFQQLIKIISPAYENQDPYHKNLYYQEIFDKLRNFISSIPHKNDKNLFNLNQMVSLHPEFFETDNTAKQKIQEEYYRLSETFKGLNQATKGFKKGQIITIGGYTGLGKTTFVYNLLLDIAKTKYQETHHHPHLLIFSYEMTLEENLSRLLSHQTKIPLNVILDKNLEDSSITQQTYMERMNDTKQFFSKLNLSFSYDKTKKIDYIIDLVYRLYLEAKVEIIVIDHLQITKATNHFDNDRLAIDEIMTKLKEIAIELNIVIIILSQFSRDTYSNYNGKSPEITALKGSGGIETNSDIVLMMSEFQPKLSKDKTKPFNIYNSTLNQLYLESDNNDNQKIIEVNIKKNRSGAKKTLIYHFEMTTQTFQEIGYVLPYQIETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ55</accession>
    <name>Q6YQ55_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YqaJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_520"/>
    <dbReference type="EnsemblBacteria" id="BAD04605">
        <property type="protein sequence ID" value="BAD04605"/>
        <property type="gene ID" value="PAM_520"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_520"/>
    <dbReference type="eggNOG" id="COG5377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1209247_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017482">
        <property type="entry name" value="Phage_endonuclease_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03033">
        <property type="entry name" value="phage_rel_nuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ" evidence="1">
        <location>
            <begin position="16"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="216" mass="25740" checksum="8BE37BBD77FE40E0" modified="2004-07-05" version="1">MIIMQIKNLNQHTKLWYQHRKKYINASEIASITGLDPFRSMKQLVHDKLFGTTFTSNQYTLHGQKMEPIAREFFNQKTNLTFEDTIFTDDKVKMFSASLDGYNEKHQAVLEIKCPYVNKNQAVSSTWTHFLTHPQLENIPQYYWAQVQCQLYCSQANFAYFLVYFNDQNYHVVRIYQNKTFIIKMIQDSQKYLELLIKVTEELTKTTYLKQLSKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ60</accession>
    <name>Q6YQ60_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04600">
        <property type="protein sequence ID" value="BAD04600"/>
        <property type="gene ID" value="PAM_515"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_515"/>
    <dbReference type="HOGENOM" id="CLU_959212_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-617-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="290" mass="32928" checksum="E71DC45313035F7C" modified="2004-07-05" version="1">MAKKIIKTKKNQSKSNKKSPQSKNNKTTKTIIKRKTPTPKIIIATQTQKENWFFKIIKNFFNILVYFIPLLLIGGAIYWTLFKFFPDIFNQINIFTSDIATKTKTLYDKATQPIRQVIEYIYNKLTGNDKDPNHIPSPQNKLGYYLTTTLSVIGICLGFGKIGNWLKNGKKKTIKKGTKTIIQKKATSKIANIGGKILKIGSKALFLVSLASTAYEIYQFYHEETKTPNPPQQLTHQIENPSITNIQTPSTQQTQKPTIIKNEEPNITNNNESKTEITQEESTTGNLNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ67</accession>
    <name>Q6YQ67_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_508"/>
    <dbReference type="EnsemblBacteria" id="BAD04593">
        <property type="protein sequence ID" value="BAD04593"/>
        <property type="gene ID" value="PAM_508"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_508"/>
    <dbReference type="HOGENOM" id="CLU_1232954_0_0_14"/>
    <dbReference type="OMA" id="FIWEHLT"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="220" mass="26116" checksum="221199FFB54F7139" modified="2004-07-05" version="1">MMILKMIFSFNFLKYLISFDFKDFFYLLYSIFYSIFFTKSSFLFGFNVGWNINFINIYNIIKTIFVFIWEHLTTLIYPLKLFSSLFDFLMQILKIFIDVFGSIIGYIKSSITSLTGQKLMDPSESMWEKIKEIAKLIFSVAVGGSVIYFLKEINNFLLNSFIKIGDLLFKIVLRILDIISIVLKFFLFLFKKVIIILSFVLSFFINFLYLWVFENAKKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="113" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ70</accession>
    <name>Q6YQ70_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">uvrD</name>
        <name evidence="8" type="ordered locus">PAM_505</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_505"/>
    <dbReference type="EnsemblBacteria" id="BAD04590">
        <property type="protein sequence ID" value="BAD04590"/>
        <property type="gene ID" value="PAM_505"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_505"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011020_0_0_14"/>
    <dbReference type="OMA" id="YDEIEWI"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="3"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="873" mass="104591" checksum="69FAC372AE63B7A3" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ82</accession>
    <name>Q6YQ82_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04578">
        <property type="protein sequence ID" value="BAD04578"/>
        <property type="gene ID" value="PAM_493"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_493"/>
    <dbReference type="HOGENOM" id="CLU_1531601_0_0_14"/>
    <dbReference type="OMA" id="ILECCIQ"/>
    <dbReference type="OrthoDB" id="1230437at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-595-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="193" mass="23414" checksum="34DE2AF1B633D9F7" modified="2004-07-05" version="1">MRIIPYELYPYASDLALCALRKEFGMYDHCLNTCKNNKAMQPFLDMKRNYFYLSFDLWVLEMQQRKHYINSFHLFYANKHKYFLINTDFILILECCIQWEIKGFMPYNTSLSWFLVALKCLEQQQEAKSQTNPHPNFVPTSSTNYYLDFCIYQKLLLWYKQTFMQANEKGNLKPKQLNMEEVKSYFQTQLKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ86</accession>
    <name>Q6YQ86_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type amino acid transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">artI</name>
        <name evidence="5" type="ordered locus">PAM_489</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_489"/>
    <dbReference type="EnsemblBacteria" id="BAD04574">
        <property type="protein sequence ID" value="BAD04574"/>
        <property type="gene ID" value="PAM_489"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_489"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_955289_0_0_14"/>
    <dbReference type="OMA" id="GMELEYA"/>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-575-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="4">
        <location>
            <begin position="50"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="320" mass="36148" checksum="04547E1D1C636E08" modified="2004-07-05" version="1">MKQNKNLIISLVVGAFVILGIIGGIVWWQLTKDKTTNQTTPTEEIALNGDLVVGMELEYAPLEWVTMGNNEQYKDQIHPIQGKKNGFACGYNVAIAKKLAKKLSKKLIIKKIDFDGLFNALTSNEVDLVIAGHTKTPEREETVAFSDPYHFGSVKVILHKDLEVNNLADLKEKKIAYQKDSAHEKKAKMISDHPQELQDLNAFNLGLLAKTIDGYILESDFAELFISKNPKLAKSVPNIDNQLMEKIKEYYDSNPQLTKEECQTFQNTKQSHIAIKKENEKLTKEVNKALEELHFTQDNQTTQALKLKAVQHSKDENANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="117" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ87</accession>
    <name>Q6YQ87_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type polar amino acid transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glnQ</name>
        <name evidence="5" type="ordered locus">PAM_488</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_488"/>
    <dbReference type="EnsemblBacteria" id="BAD04573">
        <property type="protein sequence ID" value="BAD04573"/>
        <property type="gene ID" value="PAM_488"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_488"/>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_14"/>
    <dbReference type="OMA" id="NWNQMRQ"/>
    <dbReference type="OrthoDB" id="1191583at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-574-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="248" mass="27936" checksum="50E061A5B5F919CA" modified="2004-07-05" version="1">MHNIIEITNLQKKYGTKVVLKDINLKIKQNEIITLIGPSGAGKSSLLRCLNLLEEPDFGTILFEGTNILNPKYNVYNLRKKIGMVFQHFNLFAHKNVLNNCTLAITEVFKKSKEEAQTIAREKLQKVGLLDVSSQSIQTLSGGQKQRVAIARALCMNPEIILFDEPTASLDPQLTKEVLDIMTNLTHEKITIILVTHEIAFAQKISDRIVFMADGIILEEGTPQQILNNPQSDKLKTFLKDASFNKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ90</accession>
    <name>Q6YQ90_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04570">
        <property type="protein sequence ID" value="BAD04570"/>
        <property type="gene ID" value="PAM_485"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_485"/>
    <dbReference type="HOGENOM" id="CLU_133775_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-570-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="170" mass="19407" checksum="EBBB069239B938AE" modified="2004-07-05" version="1">MEQIYIWVQKLNTDVNSILTSFEILTAKTLKFREVSKEYDNVLDKITNIFSYMKSISTLNDEIYEQDSKSSVSDESSNLDAKVQEALDQLGGINKLKDQKVHVDQLNTQFNILKDQNPLTPSGGSGSSDTSQNNNSNVTNSFLFFFFVIFILLFVVLILYFIFQNFANTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ97</accession>
    <name>Q6YQ97_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_478</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_478"/>
    <dbReference type="EnsemblBacteria" id="BAD04563">
        <property type="protein sequence ID" value="BAD04563"/>
        <property type="gene ID" value="PAM_478"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_478"/>
    <dbReference type="HOGENOM" id="CLU_1309101_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-563-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="210" mass="24980" checksum="2AAC0BD93C54BFFB" modified="2004-07-05" version="1">MHKTSSLLRLQEQPHDYLTSVNHETLPNLEITKNNFEVREIYPEIDRFLAHGDDTLIDDFYGSNKNNFVDYFQKIIQPATQEVVLQNNTQIETNLPQLKDVYAKFILKARCTIEDQATLLKTITFNDFNNPNQNGMKEKSVKDLEKLHTNYEKIYQEQKETIPKYQTFLLQQLETQKKILLIVLKIENLMKFIYNNKISYKHNYNKELMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQA0</accession>
    <name>Q6YQA0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04560">
        <property type="protein sequence ID" value="BAD04560"/>
        <property type="gene ID" value="PAM_475"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_475"/>
    <dbReference type="HOGENOM" id="CLU_3382965_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="33" mass="3890" checksum="BA8E64CB83A45CC2" modified="2004-07-05" version="1">MREGKMKKRLPPLDSLFLVKTIYFVVLKIALKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQB6</accession>
    <name>Q6YQB6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_459</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_459"/>
    <dbReference type="EnsemblBacteria" id="BAD04544">
        <property type="protein sequence ID" value="BAD04544"/>
        <property type="gene ID" value="PAM_459"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_459"/>
    <dbReference type="HOGENOM" id="CLU_065991_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-544-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="108"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="250"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="2">
        <location>
            <begin position="276"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="204"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="338" mass="39933" checksum="84881DF8B85A3E73" modified="2004-07-05" version="1">MFWIGGLAYKYHLETEEIRKLQEVDIKAKARELNDFIYNENKKLKKENEYMKDTPYEFIRDNGEKEYYNLFAHQLVKKIDKDDTIWEYDKNNGLLLKKTDKYNNVEEYGLHGKLIKKTLSDGVWMEYNSVNKKLMKRKNIDNSIEEFHDNEEKFKEIDKNGKVKFFKTKLYQNISDFKKLNLTARQLKDIGFTFQQIKEVGYTAKELKDAGSSLQELKASAQQEQETFNNILKKIESEVESLTTEQEIVYHPGGKTIKHIKILDSKNKKEIKRIIYHDDGKTINQIWETNPEGTIIKATYYQDDAKTINLIKEINPEGKPTQITYYNPDGTVKETINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQC3</accession>
    <name>Q6YQC3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04537">
        <property type="protein sequence ID" value="BAD04537"/>
        <property type="gene ID" value="PAM_452"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_452"/>
    <dbReference type="HOGENOM" id="CLU_1914934_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-534-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="132" mass="16002" checksum="3756C5290A369E6B" modified="2004-07-05" version="1">MDRNKINELKEIKKEIEDYQRKIEQLQRKIATKEKDPKIEQYQKEYYEHIKNFNLYQQQMRGITPEKELQTKIEAELAAKQKAIKAKNNLETEIKRDKIKLDYALKEQQNLYNVIYKELSPKGKEELDKNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQC8</accession>
    <name>Q6YQC8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tldD</name>
        <name evidence="4" type="ordered locus">PAM_447</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04532.2"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04532">
        <property type="protein sequence ID" value="BAD04532"/>
        <property type="gene ID" value="PAM_447"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_447"/>
    <dbReference type="eggNOG" id="COG0312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026425_1_0_14"/>
    <dbReference type="OMA" id="TDFWGSM"/>
    <dbReference type="OrthoDB" id="806701at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-527-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025502">
        <property type="entry name" value="TldD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004919">
        <property type="entry name" value="TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD_M" evidence="3">
        <location>
            <begin position="109"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="2">
        <location>
            <begin position="224"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04532.2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="459" mass="50276" checksum="A2F863A764B3A713" modified="2008-02-05" version="2">MLNKEDIQKILNLSLDKGADFAELFFENAYSHTLKVIGKDVVSADTSNTFGVGIRLLKGFDEVYGYTNKTDYQNVLSLLLKLKKSFQGKANKVIALQTEKPLKNTIQKPYNSMTQEQKAQKLLKLSAIIQNYDPQIIQSITSLSQKEQHVLIANTLGVYQNDTRNYIRCGLVGVAQRGQEMQEAFEGPGRAMGLEFLDVIDLETIAKQVAKQAVALLDAKFLKPQTMPVVINHGFGGVIFHEACGHPLEATAVAKGLSPFCNKLNQKVASEVVTAYDDGTIKASWGSLNFDDEGNPTQKNLLIEKGILKGYLIDFRNGRKMKMQSTGSSRRQSYKYSPTSRMNSTYIEKGTETPEQIIADTPYGLYAKSLGGGTVVPATGEFNFVVNEGYLIENGKLTTHVKGAMLIGHGADILFKIDRVANDLVLGQGMCGSCSGSLPVDVGQPTIRVKEMIVGGNQK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQD4</accession>
    <name>ACPS_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="1">Holo-ACP synthase</shortName>
            <ecNumber evidence="1">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">acpS</name>
        <name type="ordered locus">PAM_440</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQD4"/>
    <dbReference type="SMR" id="Q6YQD4"/>
    <dbReference type="STRING" id="262768.PAM_440"/>
    <dbReference type="PRIDE" id="Q6YQD4"/>
    <dbReference type="EnsemblBacteria" id="BAD04525">
        <property type="protein sequence ID" value="BAD04525"/>
        <property type="gene ID" value="PAM_440"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_440"/>
    <dbReference type="eggNOG" id="COG0736">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089696_1_1_14"/>
    <dbReference type="OMA" id="ILISITH"/>
    <dbReference type="OrthoDB" id="1893660at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-520-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword id="KW-0276">Fatty acid metabolism</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000175682" description="Holo-[acyl-carrier-protein] synthase">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <sequence length="127" mass="14383" checksum="9BD357F6280768EE" modified="2004-07-05" version="1">MENIGIDLVEIKKIKKIGKDILAARILSSEEHQIYQIIQNPQSQLTFLAGRWASKEALFKAFQTPQKIDPTCQNYCNWSILNDKKGAPYVKNNTCTTFFNPILISITHTDNYALALVIVKKLPQSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="110" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQE0</accession>
    <name>Q6YQE0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nuclease subunit of the excinuclease complex</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">uvrC</name>
        <name evidence="9" type="ordered locus">PAM_433</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_433"/>
    <dbReference type="EnsemblBacteria" id="BAD04518">
        <property type="protein sequence ID" value="BAD04518"/>
        <property type="gene ID" value="PAM_433"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_433"/>
    <dbReference type="eggNOG" id="COG0322">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014841_3_2_14"/>
    <dbReference type="OMA" id="HIECFDN"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0228">DNA excision</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="6">
        <location>
            <begin position="141"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="8">
        <location>
            <begin position="192"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="461" mass="54041" checksum="4C6257B428283A1C" modified="2004-07-05" version="1">MLIEETQDFFYIITNNEQEALILEANLIKKHTPKYNFKLLDDKTYPYIEITKEKHPQLKISRFKQIPPGKIIFGPYPNLKNTKETLKLLHLLYPLRRCPLASKKPCLHFHINQCLGACAGKTINYKPNIEAITKFLKGNIKDILKKLHHLMQTASEKMFYEKAQEYRDIIYAIKQTTKKQLIINQKLKNCDIFAYSFNQDQISIQILKMRQGNIVDSYHSVFSYVGFVWENILTYLNCYYQKNLKPDIIITGKSQDETILQQMITNQTLLEQILQTKVNIAHKGDKKKLYLLALKNAQNDLANNNLIYQSKDQKIQESLDKLAIIFNKDIKRIDVFDNSQLFGQAFVAARIVFNHFEFDKKLYRTFHIKGKFPNEYQAFEETLTRCYNKDKEVKNDSPDLILVDGSLGQLRQSQKTLKKLGYEIPLGALQKNNKHQLTHLVTLQEKLMLEQSPNLFYFLKV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-03-07" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQE1</accession>
    <accession>A9JQS9</accession>
    <name>UVRB_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UvrABC system protein B</fullName>
            <shortName evidence="1">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">uvrB</name>
        <name type="ordered locus">PAM_763</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-12" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
        </citation>
        <scope>SEQUENCE REVISION</scope>
    </reference>
    <comment type="function">
        <text evidence="1">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAF95573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQE1"/>
    <dbReference type="SMR" id="Q6YQE1"/>
    <dbReference type="STRING" id="262768.PAM_763"/>
    <dbReference type="EnsemblBacteria" id="BAF95573">
        <property type="protein sequence ID" value="BAF95573"/>
        <property type="gene ID" value="PAM_763"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_763"/>
    <dbReference type="eggNOG" id="COG0556">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009621_2_1_14"/>
    <dbReference type="OMA" id="EYVDRMV"/>
    <dbReference type="OrthoDB" id="95696at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-513-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0228">DNA excision</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0267">Excision nuclease</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0742">SOS response</keyword>
    <feature type="chain" id="PRO_0000227336" description="UvrABC system protein B">
        <location>
            <begin position="1"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="28"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="1">
        <location>
            <begin position="432"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="1">
        <location>
            <begin position="631"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <sequence length="670" mass="76697" checksum="D7AD92648D656D24" modified="2010-04-20" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQG4</accession>
    <name>Q6YQG4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3 8">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dam</name>
        <name evidence="9" type="ordered locus">PAM_409</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3 8"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_409"/>
    <dbReference type="REBASE" id="7517">
        <property type="entry name" value="M.PhsOYORF409P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04494">
        <property type="protein sequence ID" value="BAD04494"/>
        <property type="gene ID" value="PAM_409"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_409"/>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063430_5_0_14"/>
    <dbReference type="OMA" id="MNRHGFN"/>
    <dbReference type="OrthoDB" id="1206955at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-492-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023095">
        <property type="entry name" value="Ade_MeTrfase_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012263">
        <property type="entry name" value="M_m6A_EcoRV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000398">
        <property type="entry name" value="M_m6A_EcoRV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00571">
        <property type="entry name" value="dam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000398-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="294" mass="35092" checksum="D66D4D943AF41D0C" modified="2004-07-05" version="1">MSFYFIYGLRNTKMQKFINWVGCKKKLLPHLLPLIPKKFKTYYEPFLGSGALYLSLMPKKAILNDNDTQLIQIWKSILYNPQDFYNKALAFENFIYQYPKSQQKQQKEAFKTLLNQYNHLLTRKKKRLTKASLFFILSKYCFHGILRYKDNTSLYTNFGYKSKYKTSLLNLNDLFSLQKHFQKNKHVLLCIDYQKIIAVTKKDDFLFIDPPYYNGKNITISSFYKGVFGFTEQVKLFNCLEKADKRGVKWLYTNYDTPEIRALFKNYYFKSIKSSTTHNLTNKNNNHEIIITNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQH0</accession>
    <name>Q6YQH0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hflB</name>
        <name evidence="4" type="ordered locus">PAM_403</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_403"/>
    <dbReference type="EnsemblBacteria" id="BAD04488">
        <property type="protein sequence ID" value="BAD04488"/>
        <property type="gene ID" value="PAM_403"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_403"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="282"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="115"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="556"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="786" mass="92218" checksum="F37170CE4D56D11F" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQH3</accession>
    <name>Q6YQH3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_400"/>
    <dbReference type="EnsemblBacteria" id="BAD04485">
        <property type="protein sequence ID" value="BAD04485"/>
        <property type="gene ID" value="PAM_400"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_400"/>
    <dbReference type="eggNOG" id="COG2849">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1969318_0_0_14"/>
    <dbReference type="OMA" id="IECIAEY"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021348">
        <property type="entry name" value="DUF2963"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11178">
        <property type="entry name" value="DUF2963"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="8"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="34"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2963" evidence="1">
        <location>
            <begin position="86"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="149" mass="17377" checksum="1B780E1F2576400C" modified="2004-07-05" version="1">MINKTTIYYRADKTIDYIFENDKETGYIIKKTQYQSDGTNIDYVSEYDKDTGQEVKVTFYQFDGKTIECIAEYDKGTCKLVKDTTYQSDGKTIRKINEYNQSTGESIKDIYYQIDGKTIAYVNEYDDNGTLIQTIYYNDDGTVKDIINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQK2</accession>
    <name>Q6YQK2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_331</name>
        <name evidence="4" type="ordered locus">PAM_371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">Onion yellows</strain>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_331"/>
    <dbReference type="EnsemblBacteria" id="BAD04416">
        <property type="protein sequence ID" value="BAD04416"/>
        <property type="gene ID" value="PAM_331"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04456">
        <property type="protein sequence ID" value="BAD04456"/>
        <property type="gene ID" value="PAM_371"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_331"/>
    <dbReference type="KEGG" id="poy:PAM_371"/>
    <dbReference type="HOGENOM" id="CLU_1439732_0_0_14"/>
    <dbReference type="OrthoDB" id="2088773at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-393-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-441-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="188" mass="22464" checksum="8A1F3BFFB72B43F2" modified="2004-07-05" version="1">MFKLKNKFKIISFCLFVLLGLLFITNNYQVMAMDNNDGISENNSVVNNHIDEYNTFRNLLLTQGRISQQLINALFNHSSVTEINFLLNQIQQVHQQLINYQQRQLNNQERMLRNFDNNMTRVQLEREYLLLTQEMISAINNTPLYASEEQINTLRNIQTRIDQNQRQINIIRNQIQNNQNQPNNHRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQK7</accession>
    <name>Q6YQK7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflB</name>
        <name evidence="5" type="ordered locus">PAM_366</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_366"/>
    <dbReference type="EnsemblBacteria" id="BAD04451">
        <property type="protein sequence ID" value="BAD04451"/>
        <property type="gene ID" value="PAM_366"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_366"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:ATP hydrolysis activity"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
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    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="282"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="115"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="516" mass="59910" checksum="88E53B0F7EA2A160" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQL0</accession>
    <name>Q6YQL0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-directed RNA polymerase specialized sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fliA</name>
        <name evidence="2" type="ordered locus">PAM_323</name>
        <name evidence="3" type="ordered locus">PAM_363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="BAD04448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAD04408">
        <property type="protein sequence ID" value="BAD04408"/>
        <property type="gene ID" value="PAM_323"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04448">
        <property type="protein sequence ID" value="BAD04448"/>
        <property type="gene ID" value="PAM_363"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_323"/>
    <dbReference type="KEGG" id="poy:PAM_363"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110732_0_0_14"/>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-384-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-432-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="206" mass="24545" checksum="0D25CD14AFC34944" modified="2004-07-05" version="1">MLRQKLFKDFLKNKKNLEIRDQLIELHLPLVKKISSKFKYYPNFLTRDDLYQEGILGLIKALNNYEDLGYDFIAYANPTIKSEIKELIRKSHSPSVPQKNHKANNLSFREELYETYQKNNLNPHQLWLKQINHEIFLNKLTKKLSPKAFHIICLSFGITLGNINEDYQRCYTNAEIAEQLHLKVRQIKNIKNIAIKKLKKLYRKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQL1</accession>
    <name>Q6YQL1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_322</name>
        <name evidence="3" type="ordered locus">PAM_362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_322"/>
    <dbReference type="EnsemblBacteria" id="BAD04407">
        <property type="protein sequence ID" value="BAD04407"/>
        <property type="gene ID" value="PAM_322"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04447">
        <property type="protein sequence ID" value="BAD04447"/>
        <property type="gene ID" value="PAM_362"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_322"/>
    <dbReference type="KEGG" id="poy:PAM_362"/>
    <dbReference type="HOGENOM" id="CLU_1319853_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-383-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-431-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="208" mass="24026" checksum="5979335893CC133C" modified="2004-07-05" version="1">MVAEWNNFVNQLLLPYNYDMVFEPVSGSYMDTYFFNMLELSPKKCSFGVGFELDKKVLDLDFVELKKDLDASSNKPAWYKQFTQGLDRFVEKQKVKVLDGTGQPQKSSDGKEVYQEQKDANGETLKDENGNFMYVEKEVEIEPKVPGVNEQGKWQGTVSQFKTFFTKTLNDYANYSQYKQKTLLYVFGKLEKVVFDNLVDVPLSTLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="119" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQL3</accession>
    <name>Q6YQL3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-directed RNA polymerase specialized sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fliA</name>
        <name evidence="2" type="ordered locus">PAM_320</name>
        <name evidence="3" type="ordered locus">PAM_360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_320"/>
    <dbReference type="EnsemblBacteria" id="BAD04405">
        <property type="protein sequence ID" value="BAD04405"/>
        <property type="gene ID" value="PAM_320"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04445">
        <property type="protein sequence ID" value="BAD04445"/>
        <property type="gene ID" value="PAM_360"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_320"/>
    <dbReference type="KEGG" id="poy:PAM_360"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110732_0_0_14"/>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-381-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-429-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="209" mass="24809" checksum="0278ED5F5D9E0258" modified="2004-07-05" version="1">MLRQKLFKEFLKNKKNLEIRDQLIELHLPLIKKIVNQFKYYPRVLTKEDLYQEGILGLIKALNHYQDLGYDFIAYANPTIKSEIKELIRKSHSPSIPQKNHKKDNLSFQEDFCEPYQINKLNPHQLWLKQVKHENFLKKMKAKLSETEFKIIHLSFGVPLGNINEDYQTSYSNEEIAQKLHLSLKQVENIKNIAIKKLKKQKNVNLSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQM4</accession>
    <name>Q6YQM4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_349"/>
    <dbReference type="EnsemblBacteria" id="BAD04434">
        <property type="protein sequence ID" value="BAD04434"/>
        <property type="gene ID" value="PAM_349"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_349"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_959212_0_0_14"/>
    <dbReference type="OMA" id="KENWFLK"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="290" mass="33015" checksum="5952AA88FC25441E" modified="2004-07-05" version="1">MIRVFFYIKLKKERKTMNKKNNKKNTKKSTGKIIITKRKPITEPPKIIIETQTKKENWFLKTLKSIINKILFLLPFILIGGAIYWTLFKFFPEVLNQINAFTSDAPAKTKSLYDKATQPIRNFIEYIYHKLTGNDKDPNHNPSSQNKLGCYLATTLSVIGICLGIGKVGHWLKSGKTKTIKKGTKTIIQKKATSKIANVGGKILKIGSKALFWVSLVSTAYELYQFYHEETKIPNPPQQLTNKIENPPTPILQTQNTTIIEDEESTLTNNNEVKEETNQEESITGNLNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQN1</accession>
    <name>Q6YQN1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retron-type reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_342"/>
    <dbReference type="EnsemblBacteria" id="BAD04427">
        <property type="protein sequence ID" value="BAD04427"/>
        <property type="gene ID" value="PAM_342"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_342"/>
    <dbReference type="eggNOG" id="COG1403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013584_3_1_14"/>
    <dbReference type="OMA" id="VFIRITI"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024937">
        <property type="entry name" value="Domain_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01348">
        <property type="entry name" value="Intron_maturas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="79"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="586" mass="68596" checksum="8E1800445B614C7C" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQP7</accession>
    <name>Q6YQP7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflB</name>
        <name evidence="5" type="ordered locus">PAM_326</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_326"/>
    <dbReference type="EnsemblBacteria" id="BAD04411">
        <property type="protein sequence ID" value="BAD04411"/>
        <property type="gene ID" value="PAM_326"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_326"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="282"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="115"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="516" mass="59857" checksum="BA6F13ADF48EE31F" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQQ5</accession>
    <name>Q6YQQ5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">PAM_318</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="7519">
        <property type="entry name" value="M.PhsOYORF318P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04403">
        <property type="protein sequence ID" value="BAD04403"/>
        <property type="gene ID" value="PAM_318"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_318"/>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140323_0_0_14"/>
    <dbReference type="OMA" id="QLITIWK"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="159" mass="19073" checksum="BDB623111A2F96BE" modified="2004-07-05" version="1">MKINWIGCKKKLLPQIISHLPKQFKTYYEPFLGSGVLYFYLQPSKAILNDNDHQLITMWKQSLQNPDHFVNKVKAIENYIYQYNNQKNQKQAFKHLLNQYNQNVKKRKKLTRSVIFYVLNKYAFRGITRYDKQSNLKTNFGYKSKQKTPIINLNELVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQS3</accession>
    <name>Q6YQS3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bis(5'-nucleosyl)-tetraphosphatase (symmetrical)</fullName>
            <ecNumber evidence="2">3.6.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">PAM_300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = 2 ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24252"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.41"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.1.41" evidence="2"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_300"/>
    <dbReference type="EnsemblBacteria" id="BAD04385">
        <property type="protein sequence ID" value="BAD04385"/>
        <property type="gene ID" value="PAM_300"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_300"/>
    <dbReference type="eggNOG" id="COG1713">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089580_1_2_14"/>
    <dbReference type="OMA" id="TKMARHY"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-358-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005249">
        <property type="entry name" value="YqeK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00488">
        <property type="entry name" value="TIGR00488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="4">
        <location>
            <begin position="27"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="199" mass="23477" checksum="9F52EB183EE700E3" modified="2004-07-05" version="1">MKKNENNMLLHKIRQAVETKLKNYPLRLEHTIRVYRTATKMARHYNKPLLPIQIAALFHDYTKNDTLEQQKPYLTQANIQKYSKTPAIFHALSAANILKKEFGITNVTILNAIKKHVWGDKKMNYCDKIVLLSDKLEPQRNFSQIKYFQKLAYFNLNQAIYELLKSNFDYFSQKGSPLPYNYQEILSSLKNSIKRKIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQS5</accession>
    <name>Q6YQS5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized BCR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">PAM_298</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0154 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_298"/>
    <dbReference type="EnsemblBacteria" id="BAD04383">
        <property type="protein sequence ID" value="BAD04383"/>
        <property type="gene ID" value="PAM_298"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_298"/>
    <dbReference type="eggNOG" id="COG3763">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180108_1_0_14"/>
    <dbReference type="OMA" id="PISEEMM"/>
    <dbReference type="OrthoDB" id="2017083at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-356-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005359">
        <property type="entry name" value="UPF0154"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03672">
        <property type="entry name" value="UPF0154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="71" mass="8405" checksum="A8D52B614E238B55" modified="2004-07-05" version="1">MNNIWLYVNPIIGFLLGGVLGAFLMFHWFKKHLQQNPPISEKQIKEMFRQMGRTPSEKQIRQIMNSMKQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-04-07" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQT2</accession>
    <name>Q6YQT2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_291"/>
    <dbReference type="EnsemblBacteria" id="BAD04376">
        <property type="protein sequence ID" value="BAD04376"/>
        <property type="gene ID" value="PAM_291"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_291"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1979284_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="126" mass="13886" checksum="CB6C53436FC67A81" modified="2004-07-05" version="1">MASNLILGVDEETGFRCMKHYFSKLPEVPVSVFVPDSRFPAVYCEKGLCDFSLQGVVLDDRIISIKSGKATNVVPDLAQAVLKFDPSYKTLFNNYLPKNDTKATLEPQGDLLKITVYGKSVHGSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQT4</accession>
    <name>Q6YQT4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04374">
        <property type="protein sequence ID" value="BAD04374"/>
        <property type="gene ID" value="PAM_289"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_289"/>
    <dbReference type="HOGENOM" id="CLU_885186_0_0_14"/>
    <dbReference type="OMA" id="VIFNVKE"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="314" mass="35307" checksum="E5A3874DFB068AD8" modified="2004-07-05" version="1">MILFVISFNYTLKAAPTEPIDISTIEKNIGSFESAPNDKKIIEKILKNQKNISGLSIGDDLEVVLINNNKATVKAKENSKKIKGQVEVIFNVKEDLNVLIQNKALGDIELNKIHSEALISNEDLLNAIESKNNGLVITKEDIYFPKKDRSKGYITIEALDKSPKYKGKAKLTYQIKKINKEEFIAEVKKKYNIPFDSPIKQSQLDETIENVIAEEVGNPDSTKDLVMQKVQEAVELLLNDGNTLSETLTTSMSNKEELQNNSQTILSPKITSEKTDNNENTNYGFYIVIACIILISITFLSLLFVIFKKRNTQS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-15" modified="2022-08-03" version="119" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQT9</accession>
    <name>ENO_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enolase</fullName>
            <ecNumber evidence="1">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">eno</name>
        <name type="ordered locus">PAM_284</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cell surface</location>
        </subcellularLocation>
        <text evidence="1">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQT9"/>
    <dbReference type="SMR" id="Q6YQT9"/>
    <dbReference type="STRING" id="262768.PAM_284"/>
    <dbReference type="EnsemblBacteria" id="BAD04369">
        <property type="protein sequence ID" value="BAD04369"/>
        <property type="gene ID" value="PAM_284"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_284"/>
    <dbReference type="eggNOG" id="COG0148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031223_2_1_14"/>
    <dbReference type="OMA" id="EFMIIPV"/>
    <dbReference type="OrthoDB" id="533698at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-342-MON"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0324">Glycolysis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <feature type="chain" id="PRO_0000133939" description="Enolase">
        <location>
            <begin position="1"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="1">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="367"/>
            <end position="370"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <sequence length="430" mass="47082" checksum="95CA90307E42BDF1" modified="2004-07-05" version="1">MPYIESILAREVLDSRGNPTVEVEVYTESGAFGRAIVPSGASTGQYEAVELRDGDAQRFLGKGVLQAVKNVIEVIQPELEGYSVLEQTLIDKLLIKLDGTPNKSNLGANAILGVSLACAKAAANYLNLEFYQYVGGVLPKQMPVPMMNVINGGAHASNSVDFQEFMILPTGPTSFKEALRYGAEVFHHLGKILKQKGLPTTVGDEGGYAPDLNSNEEALQIILEAIKSAGYEPGKDIFLGMDVAASEFYDKKLQKYVLASENNKAFSSQELVHYYETLVSKYPIISIEDGLDENDWDGWKYLTQKLGNQIQLVGDDLFVTNTQKLAQGIENKIGNSILIKLNQIGTLTETLETIEMAKKASYTAVISHRSGETEDTTIADLAVATNAGQIKTGSCSRTDRMAKYNQLLRIEDQLVEAPFLGLKTFYNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="126" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQU4</accession>
    <name>Q6YQU4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA topoisomerase 1</fullName>
            <ecNumber evidence="10">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">topA</name>
        <name evidence="12" type="ordered locus">PAM_279</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="10"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_279"/>
    <dbReference type="EnsemblBacteria" id="BAD04364">
        <property type="protein sequence ID" value="BAD04364"/>
        <property type="gene ID" value="PAM_279"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_279"/>
    <dbReference type="eggNOG" id="COG0550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002929_0_2_14"/>
    <dbReference type="OMA" id="PECKYTR"/>
    <dbReference type="OrthoDB" id="223233at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-337-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="11">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="10">
        <location>
            <begin position="163"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="647" mass="74400" checksum="8D3C2E7559437595" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-07-22" modified="2022-08-03" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQV1</accession>
    <name>RNY_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribonuclease Y</fullName>
            <shortName evidence="1">RNase Y</shortName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rny</name>
        <name type="ordered locus">PAM_272</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Endoribonuclease that initiates mRNA decay.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNase Y family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQV1"/>
    <dbReference type="SMR" id="Q6YQV1"/>
    <dbReference type="STRING" id="262768.PAM_272"/>
    <dbReference type="EnsemblBacteria" id="BAD04357">
        <property type="protein sequence ID" value="BAD04357"/>
        <property type="gene ID" value="PAM_272"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_272"/>
    <dbReference type="eggNOG" id="COG1418">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028328_1_0_14"/>
    <dbReference type="OMA" id="PHAILGM"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-331-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00335">
        <property type="entry name" value="RNase_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017705">
        <property type="entry name" value="Ribonuclease_Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022711">
        <property type="entry name" value="RNase_Y_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF15">
        <property type="entry name" value="PTHR12826:SF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12072">
        <property type="entry name" value="RNase_Y_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03319">
        <property type="entry name" value="RNase_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000344913" description="Ribonuclease Y">
        <location>
            <begin position="1"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="KH" evidence="1">
        <location>
            <begin position="217"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="343"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01175"/>
        </source>
    </evidence>
    <sequence length="528" mass="60348" checksum="5D8A5C63DF580B27" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQV2</accession>
    <name>Q6YQV2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04356">
        <property type="protein sequence ID" value="BAD04356"/>
        <property type="gene ID" value="PAM_271"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_271"/>
    <dbReference type="HOGENOM" id="CLU_2393518_0_0_14"/>
    <dbReference type="OMA" id="VIEQMQF"/>
    <dbReference type="OrthoDB" id="2044456at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-330-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="103" mass="11471" checksum="F9978D93223D00BC" modified="2004-07-05" version="1">MILLAIPIIIFFSLEEESPQGSSSDEVIEQMQFSDETQNPNPAPSILEKKSLKDVFIERSGEIVEKVIKSPKVSQSLETFSNKLSSTVSKSLSQNKNQSQRKA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-02-21" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQW3</accession>
    <name>RPOB_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="1">RNAP subunit beta</shortName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpoB</name>
        <name type="ordered locus">PAM_260</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQW3"/>
    <dbReference type="SMR" id="Q6YQW3"/>
    <dbReference type="STRING" id="262768.PAM_260"/>
    <dbReference type="PRIDE" id="Q6YQW3"/>
    <dbReference type="EnsemblBacteria" id="BAD04345">
        <property type="protein sequence ID" value="BAD04345"/>
        <property type="gene ID" value="PAM_260"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_260"/>
    <dbReference type="eggNOG" id="COG0085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_4_1_14"/>
    <dbReference type="OMA" id="FMTWEGY"/>
    <dbReference type="OrthoDB" id="9601at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-317-MON"/>
    <dbReference type="BRENDA" id="2.7.7.6">
        <property type="organism ID" value="14812"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042107">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_ext_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02013">
        <property type="entry name" value="rpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000224086" description="DNA-directed RNA polymerase subunit beta">
        <location>
            <begin position="1"/>
            <end position="1273"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <sequence length="1273" mass="143378" checksum="9DDEA921A5A37F29" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQW4</accession>
    <name>Q6YQW4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rplL</name>
        <name evidence="7" type="ordered locus">PAM_259</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_259"/>
    <dbReference type="EnsemblBacteria" id="BAD04344">
        <property type="protein sequence ID" value="BAD04344"/>
        <property type="gene ID" value="PAM_259"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_259"/>
    <dbReference type="eggNOG" id="COG0222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086499_3_2_14"/>
    <dbReference type="OMA" id="LEDKWGV"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="16"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="69"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="136" mass="14819" checksum="40F5C64877923B96" modified="2004-07-05" version="1">MNEKIITKEIDMAKLTKEAFVSALKEMSLLEIKELLDGLKEEFGIDPTALAVAAPGANNSAEVEEKTEFTVVMKSFDEKKKLAVIKTVREVTGLGLLDAANFVKVPDSKVKENVSKALAEDIKNKLEQAGAVVELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="115" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQY5</accession>
    <name>Q6YQY5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pseudouridine synthase</fullName>
            <ecNumber evidence="4">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsuA</name>
        <name evidence="6" type="ordered locus">PAM_238</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="4"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_238"/>
    <dbReference type="EnsemblBacteria" id="BAD04323">
        <property type="protein sequence ID" value="BAD04323"/>
        <property type="gene ID" value="PAM_238"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_238"/>
    <dbReference type="eggNOG" id="COG1187">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024979_1_2_14"/>
    <dbReference type="OMA" id="HVPKTYE"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-286-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="2"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="245" mass="28241" checksum="F12A5CF48A8677BD" modified="2004-07-05" version="1">MQRLQKVLAYANVASRRKAEILILEKRIKVNGKIISELGTKVSSSDIITLDDKPITKTTYSYFLLNKPNGFLSTAKDNKKRPTVLDLIEEANIQRLYPIGRLDFNTTGLLLITNDGDLTQKLTHPSFCIPKEYHVKINACLQKKDLATFRKGIIIDKNYLAFCKEIDILKSSYKPKPSTWLKLVITEGKNRQVRKMMQSLGYQVLKLKRYRYSFLTIENLTIGAYRPLKIHEIKKLKTLTTQIPH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR15</accession>
    <name>RS3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsC</name>
        <name type="ordered locus">PAM_206</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR15"/>
    <dbReference type="SMR" id="Q6YR15"/>
    <dbReference type="STRING" id="262768.PAM_206"/>
    <dbReference type="EnsemblBacteria" id="BAD04291">
        <property type="protein sequence ID" value="BAD04291"/>
        <property type="gene ID" value="PAM_206"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_206"/>
    <dbReference type="eggNOG" id="COG0092">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058591_0_2_14"/>
    <dbReference type="OMA" id="KTNPIGN"/>
    <dbReference type="OrthoDB" id="1132353at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-252-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000130165" description="30S ribosomal protein S3">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="1">
        <location>
            <begin position="39"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="222"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="252" mass="28214" checksum="A5836CD399EFF552" modified="2004-07-05" version="1">MGQKTNPNGLRLGIIRTWESQWCVNDKEIPNLIKEDFLIRKLINNFTKKSAISQIDIERLKEKNKNRITISVHTAKPGVIIGKDGDTRNKLVAKLKELTQKDVNLNVLEVKNSDKIALLIAQNMAEQLENRMFFRRVQKMAIQKALKAGAKGVKTLISGRLGGAEIARSEGHAEGRVPLHTLRADIDYAAVEAHTTYGVLGIKVWIFHGEVLPGQTILDTRKPFASQSSNTPNRRPRNFKGGNNNHVNAKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR22</accession>
    <name>Q6YR22_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04281">
        <property type="protein sequence ID" value="BAD04281"/>
        <property type="gene ID" value="PAM_196"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_196"/>
    <dbReference type="HOGENOM" id="CLU_1401243_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-240-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="194" mass="22759" checksum="6C37DA359F41FF71" modified="2004-07-05" version="1">MFLSNAYNKKTLLFLIIIIFNLFIIIPHFTKAQSNLKLRYDYKTSIKISLRKKERQAQTTTQVQEEPTQEQQGPKLHLVEIEGDWDSRLDKVIKNIKEKINPNFNGTLTKRKTINRIKDGNISFEITTGTCEPSTICLYHDGEIRGDLDKKYTYQELTKMTGKYTNLYIFYHDIENTKKLDGAKNLLLDGFQEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR24</accession>
    <name>Q6YR24_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04279">
        <property type="protein sequence ID" value="BAD04279"/>
        <property type="gene ID" value="PAM_194"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_194"/>
    <dbReference type="HOGENOM" id="CLU_294709_0_0_14"/>
    <dbReference type="OMA" id="DYQETFF"/>
    <dbReference type="OrthoDB" id="88642at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-238-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="49"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="683"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="1028" mass="123206" checksum="0F82234E438C093F" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR25</accession>
    <name>Q6YR25_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">PAM_193</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_193"/>
    <dbReference type="EnsemblBacteria" id="BAD04278">
        <property type="protein sequence ID" value="BAD04278"/>
        <property type="gene ID" value="PAM_193"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_193"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="15"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="oligo_HPY" evidence="5">
        <location>
            <begin position="114"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="193" mass="22314" checksum="030E72579B5E417C" modified="2004-07-05" version="1">MTKGKKDPKYQTMILAIMKKCGIDTSLYDRYPHQLSGGQRQRIAIARALIIKPKFVVCDEIVSALDVSIQAQILNLLNDLKKDYQLTFLFITHDLGVARFLSDRICVMHLGKVIEIAPSESLFKKPYHPYTKQLLNAIPKLKTQNKALEEMPITYETNKFRFLFHTQKQDLDWYQVAPNHFISCTLKNKATKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR45</accession>
    <name>Q6YR45_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_173"/>
    <dbReference type="EnsemblBacteria" id="BAD04258">
        <property type="protein sequence ID" value="BAD04258"/>
        <property type="gene ID" value="PAM_173"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_173"/>
    <dbReference type="HOGENOM" id="CLU_2168400_0_0_14"/>
    <dbReference type="OrthoDB" id="2161705at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-212-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="110" mass="12862" checksum="9FDB6D1B382BE9C0" modified="2004-07-05" version="1">MASSNTNMNTNNTIVIVLLAIKTLVPIVVGILALRSYFKGKKIETKRCFIKWLIKDIKIRLTECDNFKLKEQFSLKIQFIVERIDDFEKQRLMEGKMFLTFVIGAFTNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="113" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR53</accession>
    <name>Q6YR53_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 10">Uracil-DNA glycosylase</fullName>
            <shortName evidence="8">UDG</shortName>
            <ecNumber evidence="4 8 10">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">ung</name>
        <name evidence="12" type="ordered locus">PAM_163</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8 10">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 10">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="4 8 10"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_163"/>
    <dbReference type="EnsemblBacteria" id="BAD04248">
        <property type="protein sequence ID" value="BAD04248"/>
        <property type="gene ID" value="PAM_163"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_163"/>
    <dbReference type="eggNOG" id="COG0692">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032162_3_0_14"/>
    <dbReference type="OMA" id="PDNGYLM"/>
    <dbReference type="OrthoDB" id="1260295at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-202-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="11">
        <location>
            <begin position="44"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="213" mass="24722" checksum="75C45FB68B083B23" modified="2004-07-05" version="1">MWQQIINNQKTKPYFKKIFTFLQEEKTNHKIIYPNQEDIFAAFNLTPFEKVKVVILGQDPYHGKNQAHGLSFSVKTFQKPPSLSNIFKELKNDLQITARTNNLTKWALEGVLMINAILTVEKDKPLSHHQIGWQEFTKTIFQALQAKPNIVYILWGKFAKTYEQYICQSQNCIIKSPHPSPFSAHRGFFGSKPFSRANNYLQTCGIKVVDWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR59</accession>
    <name>Q6YR59_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04242">
        <property type="protein sequence ID" value="BAD04242"/>
        <property type="gene ID" value="PAM_157"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_157"/>
    <dbReference type="HOGENOM" id="CLU_893232_0_0_14"/>
    <dbReference type="OMA" id="PEQNILI"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="316" mass="37049" checksum="8720452FEBABEBA5" modified="2004-07-05" version="1">MLFFMKSIQTKYYKYLIIITFIIALIILLSAIIFIKQKNKSVPNAKLSHTLPEIKPDTKTNIIEHYLGLNPNLENLKTEFRKINPDWNQEVFAYNYHMLSKSNANQKITDAIQHKIFAIFLNFNDEKMKSHQTQNNLLDALNQNPNNKMHIFWKKEKPNTELILALKDQLLHNTNKWQQTATNILDKIQTYINNDIDQILKNQLSLLEKNKIIIDMNAGKLKITDIKDFIKQNLMANANAKLESNPEQNILIKQLRKQSFNLMELRNKFQTLQKTIQKIAQNGNITTIFQKDMQELETLIKTTILEIINESDKLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="108" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR63</accession>
    <name>Q6YR63_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Hemolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">PAM_153</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_153"/>
    <dbReference type="EnsemblBacteria" id="BAD04238">
        <property type="protein sequence ID" value="BAD04238"/>
        <property type="gene ID" value="PAM_153"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_153"/>
    <dbReference type="eggNOG" id="COG1253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015237_4_0_14"/>
    <dbReference type="OMA" id="TIGRQHP"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-186-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="210"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="277"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="430" mass="49505" checksum="70F48116F8A57F32" modified="2004-07-05" version="1">MFFLMNPIVILIILIALNAFFAACEISFISTNESKIELDIKKGNKNALRVKKIKAKPTTFLSVIQIMIHIITFFQGNIVTSCWLRETEGHFSLHNIGIEALIITLSIIFGELIPKRIAMHAPSKIAYLFSGSISLIAWLITPLVWILTQVSDLFLIVFGLNPNKNSIQVSEDELRLMLTSSYQKGIIDKDENKMIQNIFEFDHTNISEVMRHRTEVVAIDVEINKKELIKTIQNEKYTRFPVYENSIDNIIGILHVKDIFNYLMSSNPNKIFDLKKFIRKPYLVPDTKNTNEFFREMKKTKTHMAIVIDEYGGTAGIITFEDLIEEILGEISDEYDNEELMIKEVAKNEYIVNGFADLEEVAEAIKLEFSTEDYDTLSGFLIGQLGRFPKPNDKNTEIIYKNFKFTILKHNDKVISQIKITKIDLKEEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR96</accession>
    <name>Q6YR96_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_119"/>
    <dbReference type="EnsemblBacteria" id="BAD04204">
        <property type="protein sequence ID" value="BAD04204"/>
        <property type="gene ID" value="PAM_119"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_119"/>
    <dbReference type="HOGENOM" id="CLU_1164925_0_0_14"/>
    <dbReference type="OMA" id="YNIFFAN"/>
    <dbReference type="OrthoDB" id="1406255at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-151-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="238" mass="28265" checksum="AFDD429EF5FBF1CE" modified="2004-07-05" version="1">MYFSITQKTKKTLHKYILAAHILALALILFHFSKQMGLYDYFRSPLTYKAYFNLALVPLFYLGFFFGFKKAYLMLFIYLFCEFVTTLGHFWILADYDIFLLEKININKVAFFILNYLLKTLIPLLSWSFTGLLYCKDLSHFNINKKNIIRLLSILIIIMLIHACLYAINGYLCYLPSIKYILKDNPYYNIFFANEITSFITIFVLNLETVITCNLLLFGCVIYLNPRLKIIYQTYFYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRA3</accession>
    <name>Q6YRA3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_112"/>
    <dbReference type="EnsemblBacteria" id="BAD04197">
        <property type="protein sequence ID" value="BAD04197"/>
        <property type="gene ID" value="PAM_112"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_112"/>
    <dbReference type="HOGENOM" id="CLU_2130885_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="113" mass="13360" checksum="8F173E2F44A1B36A" modified="2004-07-05" version="1">MMQKKNYNKKKIIGIIFFTKPNFVTEFAQKYIKYHYFPIDVKNNNSTNLIKKVEDIKKIFYNKIPSSNNNTGLCIEAENQIYYINDFPPLSQIQKITPNLLKKPVLLEKIEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRA6</accession>
    <name>Q6YRA6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04194">
        <property type="protein sequence ID" value="BAD04194"/>
        <property type="gene ID" value="PAM_109"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_109"/>
    <dbReference type="HOGENOM" id="CLU_1179267_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-141-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="235" mass="26207" checksum="9685CD7C4BA06553" modified="2004-07-05" version="1">MRNVNKNKKNKKVCGVPKVLVILGAALVATVFIVGMIISTRALNTDYVFKTKPLGTKVGKANHSLLGYLYSKFTDDNDDKKLVDLETKHLVTDTKQIKQEVGLVAKYCNDDVNNKALFKDYNLVHVGYKLVLLTTDRYNAGKNPDPSVYTQASNYDSATNVDFNEVKPGDVLLVYTLTEEGETNKDFYVVVKKDGKDVQESVFRVGIEYDGTPTLKHQKDNNGKLLYKAVDTNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRB3</accession>
    <name>Q6YRB3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="8">tRNA nucleotidyltransferase/polyA polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pcnB</name>
        <name evidence="8" type="ordered locus">PAM_102</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_102"/>
    <dbReference type="EnsemblBacteria" id="BAD04187">
        <property type="protein sequence ID" value="BAD04187"/>
        <property type="gene ID" value="PAM_102"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_102"/>
    <dbReference type="eggNOG" id="COG0617">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015961_3_0_14"/>
    <dbReference type="OMA" id="RAFYFQS"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032810">
        <property type="entry name" value="CCA-adding_enz_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13735">
        <property type="entry name" value="tRNA_NucTran2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="5">
        <location>
            <begin position="30"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="6">
        <location>
            <begin position="183"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA_NucTran2_2" evidence="7">
        <location>
            <begin position="279"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="412" mass="48776" checksum="169D93A38D473E00" modified="2004-07-05" version="1">MLKAQNMKHSNQLKTAQKIITILKTNGFEAFIVGGTVRDYLLKINANEDIDITTAAAPQQIKLLLCPEKTTQIKINYGSFKITFENYLFEITTYRKEGTYKDYRHPSEIFFTKNIHQDLLRRDFTINTLLMDETGKIFDFTPEKQGKKDLKQGLIRTIKDPFIRFQEDPLRILRAFYFQSKLGFCIEKTTQKAIIRKNHLLAKISSQRIYENIEKIITHKNWHQTFKTMIETKTHLFLPQLNQSILCLAYLHETKLKYIQAHHKLKRRIFWSMSLLLNNQILASFPFTKQKKKSYQNIASLSLYLWENITFNLFKHGLKNCLLANQINYLLQKEPYAAAKIQYIYQYLPIKTITELNFSWQEVLKQLPHKPKGTWIKHTQKQLITKVLNREIPNIKEQLINFVLSQNQILDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-12-02" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRB5</accession>
    <name>Q6YRB5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NifU-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">iscU</name>
        <name evidence="2" type="ordered locus">PAM_100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_100"/>
    <dbReference type="EnsemblBacteria" id="BAD04185">
        <property type="protein sequence ID" value="BAD04185"/>
        <property type="gene ID" value="PAM_100"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_100"/>
    <dbReference type="eggNOG" id="COG0822">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079283_4_1_14"/>
    <dbReference type="OMA" id="NCVLLPW"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="13"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="145" mass="16819" checksum="A8A5F33F73A60B58" modified="2004-07-05" version="1">MPERNKMFDSKKHEIIMKHYHNPQNQTDVRLPGYIPFEKQTSYCGDKVIIQLKCDNNKIIDIKYEANVCSICVASASVMSVYLQHLTKTQALNKINHFMAMVQNQTYDSTLFNSDLKSFDIVYQLPGKINCVLLPWQILQEFLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRD3</accession>
    <name>Q6YRD3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04167">
        <property type="protein sequence ID" value="BAD04167"/>
        <property type="gene ID" value="PAM_082"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_082"/>
    <dbReference type="HOGENOM" id="CLU_2789853_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="68" mass="7680" checksum="045891169A3AAF38" modified="2004-07-05" version="1">MLIKSNHKCIKLSDKEGGINTSLPITLLEILLIVVLDPFLRIYLGSFNNDLKYRLVPKTDPTINPEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRE0</accession>
    <name>Q6YRE0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Toprim_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">PAM_075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_075"/>
    <dbReference type="EnsemblBacteria" id="BAD04160">
        <property type="protein sequence ID" value="BAD04160"/>
        <property type="gene ID" value="PAM_075"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_075"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_952592_0_0_14"/>
    <dbReference type="OMA" id="QGENPTC"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Toprim_N" evidence="4">
        <location>
            <begin position="155"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="292" mass="35006" checksum="22FFEE31263C984F" modified="2004-07-05" version="1">MNYQEKIKHIQTHFPMLVLLKKLKILPLNFNNHHRFPCPIHQGKNPTCCHFTSNNKIHCWKCGKDYDLIDVYMVIRQIKSFSEAIQRIEGFMNSFEFKTLSQQEKETTKITINPLKQLYHSMKPKQPVDEQEINIKKKQLFQKISPLFNQIRDYYHYLLTTNRNNESQPGLTYLTKKRKLTLETIKEFKLGYAPLSDKSLSFRLVNYCKKQNIDTTKLVEYGFIKEKISQQGKKYFHDTFHGSIIIPVENGYNKTFHFYQNHFREVSYFQPKYQALTNFSQTPTLHFSYRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRF1</accession>
    <name>Q6YRF1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hflB</name>
        <name evidence="4" type="ordered locus">PAM_064</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_064"/>
    <dbReference type="EnsemblBacteria" id="BAD04149">
        <property type="protein sequence ID" value="BAD04149"/>
        <property type="gene ID" value="PAM_064"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_064"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="150"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="424"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="634" mass="74809" checksum="B189106993167A34" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRF7</accession>
    <name>Q6YRF7_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Large-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">mscL</name>
        <name evidence="10" type="ordered locus">PAM_058</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MscL family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_058"/>
    <dbReference type="EnsemblBacteria" id="BAD04143">
        <property type="protein sequence ID" value="BAD04143"/>
        <property type="gene ID" value="PAM_058"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_058"/>
    <dbReference type="eggNOG" id="COG1970">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095787_0_0_14"/>
    <dbReference type="OMA" id="MIDMAIG"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00115">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001185">
        <property type="entry name" value="MS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="PTHR30266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="SSF81330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00220">
        <property type="entry name" value="mscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="172" mass="19762" checksum="44E3507E03290B96" modified="2004-07-05" version="1">MLFLYFDTITKIITKLIFNFLLKRSFEMIENYNFTSKSLQFAKGFKAFIARGNVINLAVAVVIGQLFAKIVSSLVADIIMPLFSLLFNYTGALKDLKLEIKANTYLGYGNFLQTILEFLLLSFIIYTILTLISWKNPLQKDKVDKNMLLLQQSLDKEIALLEEIKDILKSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRG1</accession>
    <name>Q6YRG1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="5 10">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">nrdA</name>
        <name evidence="12" type="ordered locus">PAM_054</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="5 10"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_054"/>
    <dbReference type="EnsemblBacteria" id="BAD04139">
        <property type="protein sequence ID" value="BAD04139"/>
        <property type="gene ID" value="PAM_054"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_054"/>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1780">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000404_4_1_14"/>
    <dbReference type="OMA" id="RGSIQNI"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026459">
        <property type="entry name" value="RNR_1b_NrdE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013554">
        <property type="entry name" value="RNR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004465">
        <property type="entry name" value="RNR_NrdI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="PTHR11573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07972">
        <property type="entry name" value="Flavodoxin_NdrI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08343">
        <property type="entry name" value="RNR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="SSF48168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04170">
        <property type="entry name" value="RNR_1b_NrdE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIBORED_LARGE" evidence="11">
        <location>
            <begin position="628"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="769" mass="87453" checksum="C3F70034693D5504" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRG5</accession>
    <name>Q6YRG5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_050"/>
    <dbReference type="EnsemblBacteria" id="BAD04135">
        <property type="protein sequence ID" value="BAD04135"/>
        <property type="gene ID" value="PAM_050"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_050"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2701152_0_0_14"/>
    <dbReference type="OMA" id="NTKEWHQ"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-67-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="73" mass="8533" checksum="3FE7570BA2A750CD" modified="2004-07-05" version="1">MRIQNLNQRTKLWYQHRKKYINASEVASITGLDPFRSMEQLVHDKLFGTTFTANQYNLLHPSYKVPFGDLGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRG6</accession>
    <name>Q6YRG6_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_049</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="Q6YRG6"/>
    <dbReference type="STRING" id="262768.PAM_049"/>
    <dbReference type="EnsemblBacteria" id="BAD04134">
        <property type="protein sequence ID" value="BAD04134"/>
        <property type="gene ID" value="PAM_049"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_049"/>
    <dbReference type="HOGENOM" id="CLU_1999199_0_0_14"/>
    <dbReference type="OMA" id="NNQQVMG"/>
    <dbReference type="OrthoDB" id="1903537at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-65-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="89"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="125" mass="14520" checksum="BB767E786665FD8E" modified="2004-07-05" version="1">MFKIKNNLLLLLNSFIVFAFLGLFLIANNQQVMGMNKDIASASNNNQNITNYSIEENIINLKYKIRKNAVKKINTEREIQQLSNNDPNKNTLLALKQNLENLIHNQKEQLKTYQKLLKTLNDENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRG7</accession>
    <name>Q6YRG7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_048"/>
    <dbReference type="EnsemblBacteria" id="BAD04133">
        <property type="protein sequence ID" value="BAD04133"/>
        <property type="gene ID" value="PAM_048"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_048"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1137139_0_0_14"/>
    <dbReference type="OrthoDB" id="1779749at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-64-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="241" mass="28486" checksum="A328309113B53433" modified="2004-07-05" version="1">MFNIKKIIKWVFIVLGILLFLLIGFIVLTEIEIIKLPKEEIPILKETAFENIEEWDDLNSGLKMIKAKYTFDGLNGIGYYQQQLANKDNIGTFQLMAIQDRLETQKEPSNLVCYIKDRHPFDRWNKKGYTYNHTTLDGFDSASFDKKDDSQLYLYVNFEKQQHKGPGGHYLIVKYKGPKYFLEDDKDYYLGRARVHDANFELTDFRLHFNPVRKTLSLYQDKHNNDKVKEAEMKKNHPGWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRJ1</accession>
    <name>Q6YRJ1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">PAM_023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_023"/>
    <dbReference type="EnsemblBacteria" id="BAD04108">
        <property type="protein sequence ID" value="BAD04108"/>
        <property type="gene ID" value="PAM_023"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_023"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_0_14"/>
    <dbReference type="OMA" id="TFQPIVG"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-31-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="166"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="368" mass="42191" checksum="BCDD2E5EAAA52C2C" modified="2004-07-05" version="1">MILVVLFFTAVGPFINPLPKTTQEKEKSWIALLPLKIPFLEKFGIFDGTKKVDLYLDEIEQIKKFNPNIIKKQQAIKDNKQTVILDAYLYCEYEKSYINLTFTQKEYDRAKQNKSLIASTPLQNGLYRVKIRLFKYVFNKTSEKTYFYFGTTHEGNDLFTQVWKGSFISLSFAFIVSVCTLIIGTIIGAICGYYGVLVDLIVNSIVDFLSYLPFMTLVLVLMLKVGISFWTIIGVFLIKGWIGAFYYSRASFYRYKNKEYIISARMLGASDLRIMFKHIFPNIIGLMITSFALAIPGFILTEAVYSFVGVIKYPEGFISIGELLDKSFDKIGSFSYLLILPMSYLIYLMFAFNLLGNNLREAFDPASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRJ3</accession>
    <name>Q6YRJ3_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04106">
        <property type="protein sequence ID" value="BAD04106"/>
        <property type="gene ID" value="PAM_021"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_021"/>
    <dbReference type="HOGENOM" id="CLU_2035646_0_0_14"/>
    <dbReference type="OrthoDB" id="2214303at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-27-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="121" mass="14436" checksum="308754326D93ACE9" modified="2004-07-05" version="1">MLFLLKKIFLYRFYQKKVVTWTVLPLLVVGVVLGYLLWPKSQVLKVKFYNQEGKVVKEFKVDKNTKLLDKDTNKQDFESLGNKFRWCLESDKNKQVDSNRLKKVQTVKKFIKSKKMQMAKL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRK5</accession>
    <name>RS6_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsF</name>
        <name type="ordered locus">PAM_009</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04094" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04094.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRK5"/>
    <dbReference type="SMR" id="Q6YRK5"/>
    <dbReference type="STRING" id="262768.PAM_009"/>
    <dbReference type="EnsemblBacteria" id="BAD04094">
        <property type="protein sequence ID" value="BAD04094"/>
        <property type="gene ID" value="PAM_009"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_009"/>
    <dbReference type="eggNOG" id="COG0360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113441_5_3_14"/>
    <dbReference type="OMA" id="ITEASPM"/>
    <dbReference type="OrthoDB" id="1776954at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-14-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000176809" description="30S ribosomal protein S6">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="95" mass="11377" checksum="43FABF4DF845B2C2" modified="2005-03-15" version="2">MKKYEIMYILRPNLDSKDVKKINDTLQNVFLQAPNQILEQNEIGLKDLAYLIDNHKKGYYNWLMVKADNDAVLEFNRIVKITEEIIRFIFIKDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRL1</accession>
    <name>Q6YRL1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04088">
        <property type="protein sequence ID" value="BAD04088"/>
        <property type="gene ID" value="PAM_003"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_003"/>
    <dbReference type="HOGENOM" id="CLU_1843093_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-6-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="139" mass="16376" checksum="56D048EEDE92990E" modified="2004-07-05" version="1">MFGAFDLKYIKNNEGKQIYTISYLRQKGDYEDKELVKEGFNVEDFKEIGYQLPQLIEIFSLKKLNKSGYSLEEIKNLDPQTESFFYLKQFSARDLKDKVGFTLQEMQLYNYNLKDFAKGGISIQEIKETPIYINPPKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="110" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRL2</accession>
    <name>Q6YRL2_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dnaN</name>
        <name evidence="13" type="ordered locus">PAM_002</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_002"/>
    <dbReference type="EnsemblBacteria" id="BAD04087">
        <property type="protein sequence ID" value="BAD04087"/>
        <property type="gene ID" value="PAM_002"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_002"/>
    <dbReference type="eggNOG" id="COG0592">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038149_2_0_14"/>
    <dbReference type="OMA" id="YLIMPVR"/>
    <dbReference type="OrthoDB" id="1040142at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-2-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="132"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="259"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAD04087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="378" mass="43979" checksum="BA3E74AEEE66C7AF" modified="2004-07-05" version="1">MYLEINKDIFLEQLLKIQKILPQKTFFPIFNALKIQTQENNLILEANNGNIAIKIEIKDESLKIKKQGKIACLGRYFIEIIKKISDSLIKITVMENNFLVIKTSFCEYKLKLMDVCNFLELDFSFQKLDSFQIETHFLKNMIKEINISTSKNEKRPILMGLNLIYQNNLLKACATDSFRMSQKKINLDIEYHNFNIVIPNKSLEELSKILEHCQSKYLKIYSDTQKIFLEIDNLWFQTSLLEGNYPQIQEIKLTNFPFSVHLNKDDLMKALERVSLLFSKEQMNTNVIKFILTKQNSIEISSSSESLGTALEKIIPLKVSANSFQIAFNAKYLEDVLKVLSVKEVVFYFDNPLKPFIITTLEKDSSIHLILPIPFEND</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-06-07" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q7M1T6</accession>
    <accession>P81957</accession>
    <name>AMP_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName>Antigenic membrane protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Immunodominant membrane protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">amp</name>
        <name type="ordered locus">PAM_122</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Microbiology" volume="150" first="135" last="142">
            <title>Secretion of immunodominant membrane protein from Onion yellows phytoplasma through the Sec protein-translocation system in Escherichia coli.</title>
            <authorList>
                <person name="Kakizawa S."/>
                <person name="Oshima K."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Tanaka M."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14702406"/>
            <dbReference type="DOI" id="10.1099/mic.0.26521-0"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="submission" date="1999-07" db="UniProtKB">
            <title>Analysis of phytoplasmal proteins isolated by two dimensional gel electrophoresis.</title>
            <authorList>
                <person name="Zhon B."/>
                <person name="Tanaka M."/>
                <person name="Matsuda I."/>
            </authorList>
        </citation>
        <scope>PROTEIN SEQUENCE OF 33-73</scope>
        <source>
            <strain>OY-W</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AB110271">
        <property type="protein sequence ID" value="BAD07009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="A58995">
        <property type="entry name" value="A58995"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q7M1T6"/>
    <dbReference type="SMR" id="Q7M1T6"/>
    <dbReference type="EnsemblBacteria" id="BAD04207">
        <property type="protein sequence ID" value="BAD04207"/>
        <property type="gene ID" value="PAM_122"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_122"/>
    <dbReference type="HOGENOM" id="CLU_1188981_0_0_14"/>
    <dbReference type="OMA" id="TLECKDA"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-154-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029216">
        <property type="entry name" value="Phyto-Amp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15438">
        <property type="entry name" value="Phyto-Amp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0903">Direct protein sequencing</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000020723" description="Antigenic membrane protein" evidence="3">
        <location>
            <begin position="33"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; BAD07009." evidence="3" ref="1">
        <original>N</original>
        <variation>T</variation>
        <location>
            <position position="6"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; BAD07009." evidence="3" ref="1">
        <original>N</original>
        <variation>S</variation>
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 3; AA sequence." evidence="3" ref="3">
        <original>S</original>
        <variation>T</variation>
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; BAD07009." evidence="3" ref="1">
        <original>ILN</original>
        <variation>VLS</variation>
        <location>
            <begin position="107"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; BAD07009." evidence="3" ref="1">
        <original>E</original>
        <variation>D</variation>
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; BAD07009." evidence="3" ref="1">
        <original>V</original>
        <variation>F</variation>
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; BAD07009." evidence="3" ref="1">
        <original>K</original>
        <variation>N</variation>
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000269" key="2">
        <source ref="3"/>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="233" mass="24743" checksum="715E9D3AFB3103E7" modified="2004-06-07" version="3" precursor="true">MQNQKNQKSLVAKVLVLFAAVALMFVGVQVFADDKLDLNTLECKDALELTAADAADAEKVVKQWKVQNTSLNAKVTKDSVKVAVADNKVTVTPADGDAGKALSGSKILNLVGVCELNKLTLGTEKKLTLTVKDGKVDAEAGLKALKEAGAKVPATVNKDDVTFTVGKDDNANKVTVKAVDGKTTVSGQVVFEFTVAKTPWYKTVWFLTLVAVVVVAAVAGGVFFFVKKNKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-02-05" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A9JQZ8</accession>
    <name>A9JQZ8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAF95565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_755"/>
    <dbReference type="EnsemblBacteria" id="BAF95565">
        <property type="protein sequence ID" value="BAF95565"/>
        <property type="gene ID" value="PAM_755"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_755"/>
    <dbReference type="HOGENOM" id="CLU_185809_0_0_14"/>
    <dbReference type="OMA" id="NDTYPIK"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-506-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF95565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="69" mass="8099" checksum="CCE2AD2F0DD204A0" modified="2008-02-05" version="1">MTDSNFTIGFVSGALFVTGLCFVFKYLFFSFLQLFNPNDTYPIKRKTKENETSKPINQKNIKEFKKGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-02-05" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A9JR02</accession>
    <name>A9JR02_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase sigma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpoD</name>
        <name evidence="2" type="ordered locus">PAM_760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAF95570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_760"/>
    <dbReference type="EnsemblBacteria" id="BAF95570">
        <property type="protein sequence ID" value="BAF95570"/>
        <property type="gene ID" value="PAM_760"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_760"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110732_0_0_14"/>
    <dbReference type="OMA" id="FEENQPQ"/>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-510-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF95570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="208" mass="24664" checksum="5FC0E12B11A1EA83" modified="2008-02-05" version="1">MLRQNLFKDFLKNKKNLEIRNHLIELHLPLVKKLTYQFKYYPRVLTKEDLYQEGILGLIKALNNYQDLGYDFVTYATPKIKFAINELIRKSHSPSIPQKTTKPNNISFKEEQHKQPNWDKILNPHQLWLKQIKYELLIKKLKTKLSKNEFNVICLSFGISLENNNEPNQQPLSNHAIAQKLNLTLKQIENLKKDAIKKLNPNYKNKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-02-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A9JR05</accession>
    <name>A9JR05_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pmbA</name>
        <name evidence="5" type="ordered locus">PAM_764</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAF95574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF95574">
        <property type="protein sequence ID" value="BAF95574"/>
        <property type="gene ID" value="PAM_764"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_764"/>
    <dbReference type="eggNOG" id="COG0312">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026425_4_0_14"/>
    <dbReference type="OMA" id="LYRKSTF"/>
    <dbReference type="OrthoDB" id="958356at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-528-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD_M" evidence="4">
        <location>
            <begin position="131"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="242"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF95574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="458" mass="50590" checksum="FFB5C0FD66BDCD50" modified="2008-02-05" version="1">MINDVTKTPKLQSQTTHTNPTPNNYQKWLEKGMQQGFEALEIAIHESQTFKLSLDKGKIDACVWSDVASAVIRGIFANKKTSIALEQLTGSAFDNAFETLKENCQTITSKEPALIFEGSSSYPEVLENNFDFGQVPLEQKQSLLLQLEKTMLQSSHLQATNGIIYQEFYHKKTLLNSKGLNLSHQNSFAYLYASAVFQKEGEIESYGKSILAKDFVTFNPVKLGTEIVEMGEKKLGAKSLVSQKYPVVFSNEMFADLLESFSDIFTGTSAYRNLTKLKDKVNCLIASEKVSIIDDPLNDGAYFKEKFDDEGVACQTKPIITKGVFQGFIHNLKTARIFKQAPTGNGFDGSTSMINCYLVPGKKSFSEMIEPIQNGIYITDLVGMHAGIKTVSGDFSLQASGFRIEKGKVTTPVKMIVVSGNFFDILKNVDTIANDFEFQTSGFGSSSVYVGDLNIGGK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-02-16" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>P60470</accession>
    <name>REPE_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName>Geminivirus-like replication protein</fullName>
            <ecNumber>3.1.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">rep</name>
        <name type="ordered locus">PAM_780</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid">
        <name>EcOYM</name>
    </geneLocation>
    <reference key="1">
        <citation type="journal article" date="2002" name="Microbiology" volume="148" first="1389" last="1396">
            <title>Evidence of intermolecular recombination between extrachromosomal DNAs in phytoplasma: a trigger for the biological diversity of phytoplasma?</title>
            <authorList>
                <person name="Nishigawa H."/>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Jung H.Y."/>
                <person name="Kuboyama T."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="11988512"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Introduces an endonucleolytic nick, thereby initiating the rolling circle replication (RCR).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Divalent metal cations, possibly Mg(2+) or Mn(2+).</text>
    </comment>
    <comment type="domain">
        <text>There are 3 rolling circle replication (RCR) motifs. RCR-2 may be involved in metal coordination. RCR-3 is required for phosphodiester bond cleavage for initiation of RCR.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the geminiviridae Rep protein family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.-"/>
    <dbReference type="EMBL" id="AB076263">
        <property type="protein sequence ID" value="BAD04084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959585.1">
        <property type="nucleotide sequence ID" value="NC_019167.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959591.1">
        <property type="nucleotide sequence ID" value="NC_019168.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959597.1">
        <property type="nucleotide sequence ID" value="NC_019169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P60470"/>
    <dbReference type="OMA" id="TITHYEY"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Plasmid EcOYM"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022690">
        <property type="entry name" value="Gemini_AL1_REP_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00799">
        <property type="entry name" value="Gemini_AL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0614">Plasmid</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000222221" description="Geminivirus-like replication protein">
        <location>
            <begin position="1"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RCR-1" evidence="1">
        <location>
            <begin position="19"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RCR-2" evidence="1">
        <location>
            <begin position="64"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RCR-3" evidence="1">
        <location>
            <begin position="128"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="active site" description="For DNA cleavage activity" evidence="1">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="269"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="434" mass="51992" checksum="5E02EA3F9DEBF000" modified="2004-02-16" version="1">MKKTNNIKKETMFQAQNIFLTYSQCDLSKEEIKTFIINLCNEKKLQINYLIIGIENHQDHKGKHHHVFFQLNKQFRTRDLTIFNIPKNIKEKKLIDHENIKIKDFFYSPHIEPRPGNPIKDTTDVRNYVKKDGDFIEEGTFKHVRYIKLSKNEKPTELESLTNNYFLKLRKEYQQKEINISKTKNEIFKKLKLYAESLEPNYAFKNAKRFKNMVFEYIFESDIKELPIFDFCTFKKIPILISIYDILETQKEQLSNSISKRFKTLIVEGNSKSGKTQFFKSVLTNLELPFNYIKDDVDFSDENYDEDKCVNIYDDIDIYDIQARNLTKVVIGNQKDSIVNMKYKPRTKIKGTDISIMLVNEDTSIEKYCFDNFKRGRKEYKYIRENAIFINLDKHTITHYEYQKYENEQAVIQHFEMPKNWDGLLYFLDQENES</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-03-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>P60554</accession>
    <name>KGUA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Guanylate kinase</fullName>
            <ecNumber evidence="1">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gmk</name>
        <name type="ordered locus">PAM_737</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P60554"/>
    <dbReference type="SMR" id="P60554"/>
    <dbReference type="STRING" id="262768.PAM_737"/>
    <dbReference type="EnsemblBacteria" id="BAD04822">
        <property type="protein sequence ID" value="BAD04822"/>
        <property type="gene ID" value="PAM_737"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_737"/>
    <dbReference type="eggNOG" id="COG0194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001715_1_2_14"/>
    <dbReference type="OMA" id="EWAVVHG"/>
    <dbReference type="OrthoDB" id="1502854at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-892-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000170577" description="Guanylate kinase">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate kinase-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <sequence length="212" mass="24466" checksum="12E96B01513A52E0" modified="2004-03-15" version="1">MKLNKKGLLIVLSGPSGVGKATVRKALFEMTNHNFVYSVSATTRKPRPGEQDGKDYHFLTKEEFEKGIENNCFLEWAKFIDHYYGTPKKQIQDFLKQGKEVFLEIEVEGATHLRKKRIPNTVFIFLVPPEKKALYDRLKKRGTEQEANIAKRIAKANNEFHLAHKYDYIVVNDEVANAADRIIAIIRAEHAKTKRSIRNYLKILEDNGYAEQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-04-13" modified="2022-08-03" version="108" xmlns="http://uniprot.org/uniprot">
    <accession>P60918</accession>
    <name>SYH_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="1">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisS</name>
        <name type="ordered locus">PAM_127</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P60918"/>
    <dbReference type="SMR" id="P60918"/>
    <dbReference type="STRING" id="262768.PAM_127"/>
    <dbReference type="EnsemblBacteria" id="BAD04212">
        <property type="protein sequence ID" value="BAD04212"/>
        <property type="gene ID" value="PAM_127"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_127"/>
    <dbReference type="eggNOG" id="COG0124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025113_1_1_14"/>
    <dbReference type="OMA" id="YQIQKVW"/>
    <dbReference type="OrthoDB" id="277998at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-159-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000136214" description="Histidine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <sequence length="422" mass="48852" checksum="A40A47D8A74BD4F8" modified="2004-04-13" version="1">MFSKIKGTYDLMSDKMVCWQKVENHIRTLFAKYHLQEIRTPIIEYRGVFDRAAQHSEMVSKETYTFADKKERFITLRPEGTAGVIRSYVENKLDKTSQLHKFFYYGPCFRYERPQKGRYRQFHQVGVEILGQSNPFLDVEVIALAYETIKSLGICDITVKINSLGCKTTYNNYLQVFKNYLQAHYQQLCPLCQERFEKNILRIWDCKNCNNEPFLKQAPRIFDHLVEDAKVRFLQVLEGLKQMNVNFELCHDLVRGLDYYTHSVFEIVYNNEQGHQAVLGGGGCYDNLVTLFGGNPSPGIGFALGMERLMSILATHSFCNKNILPSLDAFILVSVPQFFYQGLALATTLRHQGFSADLNYQFLSFSKSLKQALKQQPLYLLILGPKEFDNNQITIKNTDTQQQTTILQKDVVSYFQNNKELN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-05-10" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>P61308</accession>
    <name>RRF_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-recycling factor</fullName>
            <shortName evidence="1">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">frr</name>
        <name type="ordered locus">PAM_168</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P61308"/>
    <dbReference type="SMR" id="P61308"/>
    <dbReference type="STRING" id="262768.PAM_168"/>
    <dbReference type="EnsemblBacteria" id="BAD04253">
        <property type="protein sequence ID" value="BAD04253"/>
        <property type="gene ID" value="PAM_168"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_168"/>
    <dbReference type="eggNOG" id="COG0233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073981_2_0_14"/>
    <dbReference type="OMA" id="FNPMNNG"/>
    <dbReference type="OrthoDB" id="1674344at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-207-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000167507" description="Ribosome-recycling factor">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <sequence length="184" mass="20799" checksum="C9A3DBDB274C417D" modified="2004-05-10" version="1">MQQLAKDILASLETKMTQAQEVMLKNFCDIRTGTANPNILDKITVNYYGAPTFLKTLASISVSEGNQLNIKPYDSTLIPNIKKVLLASNLGITPQTDGLVVRLVFPKPTEERRKALMKEVEQLAEKTKVAIRNVRREGNDKIKKVELTKDLETFYLNQIQTLTDKNIKLIEKHTTTKNTELLKA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-03-01" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>P81958</accession>
    <name>HSP16_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName>Probable Hsp20 family chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">PAM_028</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="1999-07" db="UniProtKB">
            <title>Analysis of phytoplasmal proteins isolated by two dimensional gel electrophoresis.</title>
            <authorList>
                <person name="Zhon B."/>
                <person name="Tanaka M."/>
                <person name="Matsuda I."/>
            </authorList>
        </citation>
        <scope>PROTEIN SEQUENCE OF 1-26</scope>
        <source>
            <strain>OY-W</strain>
        </source>
    </reference>
    <comment type="function">
        <text>Probable chaperone.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04113" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04113.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P81958"/>
    <dbReference type="SMR" id="P81958"/>
    <dbReference type="STRING" id="262768.PAM_028"/>
    <dbReference type="EnsemblBacteria" id="BAD04113">
        <property type="protein sequence ID" value="BAD04113"/>
        <property type="gene ID" value="PAM_028"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_028"/>
    <dbReference type="eggNOG" id="COG0071">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046737_8_0_14"/>
    <dbReference type="OMA" id="DESAQWL"/>
    <dbReference type="OrthoDB" id="1523369at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-37-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0903">Direct protein sequencing</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000126053" description="Probable Hsp20 family chaperone">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="sHSP" evidence="1">
        <location>
            <begin position="25"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 2; AA sequence." evidence="2" ref="2">
        <original>T</original>
        <variation>L</variation>
        <location>
            <position position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="137" mass="16135" checksum="2A2C0D72FB688796" modified="2004-03-01" version="1">MLFSLINQNQDLLENLFEDFKTNSLTNNNNIMKTDIQEQDNQYFITIELPGFKKEDVKVALEEGYLVVEAKNSKKNQIKEANFIRKERFQGFLRRSFYLGDDFLLEDIKGSLEQGLLKLSVPKKEVKPKEKHYIKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPH4</accession>
    <name>Q6YPH4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_753</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_753"/>
    <dbReference type="EnsemblBacteria" id="BAD04838">
        <property type="protein sequence ID" value="BAD04838"/>
        <property type="gene ID" value="PAM_753"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_753"/>
    <dbReference type="HOGENOM" id="CLU_3330905_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="38" mass="4567" checksum="A8C414AF313693C2" modified="2004-07-05" version="1">MLGISLLLIFKKQKNCKIIFNIFLTINCQYFLNIYKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPH6</accession>
    <name>Q6YPH6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type sugar transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ugpA</name>
        <name evidence="6" type="ordered locus">PAM_751</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_751"/>
    <dbReference type="EnsemblBacteria" id="BAD04836">
        <property type="protein sequence ID" value="BAD04836"/>
        <property type="gene ID" value="PAM_751"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_751"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_14"/>
    <dbReference type="OMA" id="LWYSVQS"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-906-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="80"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="313" mass="36240" checksum="5262FF38B7DB45AE" modified="2004-07-05" version="1">MSLLKKLFHHNSTKYSKHNHWYYLAPALILMVLFNFYPLVKTLFISLDSRYNKFADTFSYSFNFSNYTTTFCDPDFRTALFNTFLLVFVAVPISIFLSLMIALALNSVYNRFLKNIFQTIFFLPYLTNPVIMGMVFAVLFYHNSFGIQTRPEGFFNSFFGLQQDWINISAPYSYKMFVLIFYVVWKSLPFQILIFSVGLKNISKDYYDAAGIDGASKITIFRKITLPLLAPTIFYQLIIAIIQVFKEYESVVGVFGNSDITKVNTVVGYIYQQLEGTLMDSYSRGAAATVILLLISIIFTTINFFFFEKKLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPH8</accession>
    <name>Q6YPH8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar-binding periplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ugpB</name>
        <name evidence="3" type="ordered locus">PAM_749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_749"/>
    <dbReference type="EnsemblBacteria" id="BAD04834">
        <property type="protein sequence ID" value="BAD04834"/>
        <property type="gene ID" value="PAM_749"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_749"/>
    <dbReference type="eggNOG" id="COG1653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_520376_0_0_14"/>
    <dbReference type="OMA" id="ASWLFLK"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-904-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="540" mass="63107" checksum="BCBF19B391CE06DA" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPI7</accession>
    <name>Q6YPI7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Endo-1,4-beta-glucanase homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">frvX</name>
        <name evidence="9" type="ordered locus">PAM_740</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_740"/>
    <dbReference type="EnsemblBacteria" id="BAD04825">
        <property type="protein sequence ID" value="BAD04825"/>
        <property type="gene ID" value="PAM_740"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_740"/>
    <dbReference type="eggNOG" id="COG1363">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047249_0_2_14"/>
    <dbReference type="OMA" id="FGWPAIH"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="354" mass="38434" checksum="3534C628FC963BA5" modified="2004-07-05" version="1">MKMSDLVSLLKDLTMLNGIPGQEKAVANYVVDKIKNQVDSIEYDNLGSVIACKGKTGPRIMFAGHLDEIGLIVKQITPEGFIKFQTLGGWFSQVMLAQVWQIHTDKGVLKAVTGCKPPHVMSFQERNQVINTSSMYLDIGVANKEEALKLGVRVGDMVTPYIEFSTLGNSDYLLAKALDNRVGVAIVMQVLENVNPTTNQFFGVFTTQEEVGLRGAQTSAHKVHPQIAIAVDTGIGNDVPGGEKEGHTLGKGPQVLVYDGGLVAHKGLRNFVLKIAAQNNIPVQEISGSGGRTDAATMHLVREGAASLSFGVPVRYIHSHTSVVHKQDIINTVKLLTLLVNQLDEKKVNEILFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPJ7</accession>
    <name>Q6YPJ7_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UvrD_C_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_728"/>
    <dbReference type="EnsemblBacteria" id="BAD04813">
        <property type="protein sequence ID" value="BAD04813"/>
        <property type="gene ID" value="PAM_728"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_728"/>
    <dbReference type="eggNOG" id="COG0210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011020_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD_C_2" evidence="1">
        <location>
            <begin position="49"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="697" mass="83405" checksum="FF55880B7FD7D020" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPK3</accession>
    <name>Q6YPK3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Toprim_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">PAM_722</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_722"/>
    <dbReference type="EnsemblBacteria" id="BAD04807">
        <property type="protein sequence ID" value="BAD04807"/>
        <property type="gene ID" value="PAM_722"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_722"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3009854_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-875-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Toprim_N" evidence="4">
        <location>
            <begin position="7"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="56" mass="6659" checksum="94C6155F8BFA8433" modified="2004-07-05" version="1">MQEAADFYSHQLKHNKQVLNYLEQRGFDNDIIKHFKLGYAPKASHLSRYLMEGTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPK6</accession>
    <name>Q6YPK6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_719"/>
    <dbReference type="EnsemblBacteria" id="BAD04804">
        <property type="protein sequence ID" value="BAD04804"/>
        <property type="gene ID" value="PAM_719"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_719"/>
    <dbReference type="HOGENOM" id="CLU_3101560_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="51" mass="6348" checksum="7EDF96346977A22B" modified="2004-07-05" version="1">MKILFLSLNIYYFYFLIFKEMICLFEPYLIKQKYEFFYKITTGVMYVSFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPM4</accession>
    <name>Q6YPM4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_701"/>
    <dbReference type="EnsemblBacteria" id="BAD04786">
        <property type="protein sequence ID" value="BAD04786"/>
        <property type="gene ID" value="PAM_701"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_701"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_197523_0_0_14"/>
    <dbReference type="OMA" id="PQTHAYT"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="78" mass="9092" checksum="014D9C933B8BA6AF" modified="2004-07-05" version="1">MLNKVQLIGNIAHNLEKQYINSNNEQIPKIDFNLAINNKDKVQYIPCVVFRNQAENMTLTYPQTHAYTPKFCDFIFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPM5</accession>
    <name>Q6YPM5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase specialized sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fliA</name>
        <name evidence="2" type="ordered locus">PAM_700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_700"/>
    <dbReference type="EnsemblBacteria" id="BAD04785">
        <property type="protein sequence ID" value="BAD04785"/>
        <property type="gene ID" value="PAM_700"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_700"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110732_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="47"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="228" mass="27031" checksum="B538CF5FB8904098" modified="2004-07-05" version="1">MFFKRNKKKKLYSSFLKTFLERIQMKRKDLFLLFLKNKKNFEIRDQLIELHLPLVKKISSKFKYYPKLLTKEDLYQEGVLGLIKALDNYQDLGYDFIAYATPTIKSTINELIRKSHSPSIPQKTTKPNNISFKEQHYEPDRITNPNPHQLWLKQVNHEQLIKKLKSKLSKNEFNVICLSFGITLENITKNHQPTFTNQEIAQKLNLNLRQVETIKNIAIRKLSPNNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPN7</accession>
    <name>Q6YPN7_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">tmk</name>
        <name evidence="5" type="ordered locus">PAM_688</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_688"/>
    <dbReference type="EnsemblBacteria" id="BAD04773">
        <property type="protein sequence ID" value="BAD04773"/>
        <property type="gene ID" value="PAM_688"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_688"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049131_0_2_14"/>
    <dbReference type="OMA" id="AMEPKTW"/>
    <dbReference type="OrthoDB" id="1585072at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-839-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="4">
        <location>
            <begin position="6"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="209" mass="24118" checksum="11271D75B4352096" modified="2004-07-05" version="1">MKLIIFEGLDGSGKTGLIKSVKHGLKKQGKEVIVIRGLGSSTIGESIRETFLTHNKLHNLTRYFLSFANMIQTQEELIKPHLETNKIILVDRWLGSNFAYRVYPNRIDKKYYFFNNLTKLFIKPNLTVYLKIDPQTGLNRKANQTNHTLDVIETSPLSYFYQVEKGFQEFLNKKLGPQIILNAMEPKTWKSNTKQIIKKIGEISNVNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPR8</accession>
    <name>Q6YPR8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04742">
        <property type="protein sequence ID" value="BAD04742"/>
        <property type="gene ID" value="PAM_657"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_657"/>
    <dbReference type="HOGENOM" id="CLU_2247278_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-802-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="104" mass="11981" checksum="ED69CD8B1F37FBA5" modified="2004-07-05" version="1">MISDISDICINFFNKVKSFLSKVKQYLIKNKVFWYFNYFLVAVCIFLLLWLHIKVFAKKHSNPNALKGGIFVGIGPVCVQSDEDDSVSVNCSKTLDTFYFLKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPU3</accession>
    <name>Q6YPU3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ArsC family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_632"/>
    <dbReference type="EnsemblBacteria" id="BAD04717">
        <property type="protein sequence ID" value="BAD04717"/>
        <property type="gene ID" value="PAM_632"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_632"/>
    <dbReference type="eggNOG" id="COG1393">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116644_1_1_14"/>
    <dbReference type="OMA" id="IMIDDKR"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006504">
        <property type="entry name" value="Tscrpt_reg_Spx/MgsR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01617">
        <property type="entry name" value="arsC_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="2">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="101" mass="12115" checksum="354F95E7762DC37E" modified="2004-07-05" version="1">MVIVYTSFSCFSCKKVKKWLKAHGVRYEERNFLNYKMQSQDLDLILKNCDYGFDDIISRRSKIFKEKQIDLETINNDNIKKIIIENPEILKRPIIIKDQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="140" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPV0</accession>
    <name>Q6YPV0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GTPase Era</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 12" type="primary">era</name>
        <name evidence="12" type="ordered locus">PAM_625</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_625"/>
    <dbReference type="EnsemblBacteria" id="BAD04710">
        <property type="protein sequence ID" value="BAD04710"/>
        <property type="gene ID" value="PAM_625"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_625"/>
    <dbReference type="eggNOG" id="COG1159">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038009_1_0_14"/>
    <dbReference type="OMA" id="WAEVDVI"/>
    <dbReference type="OrthoDB" id="984717at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-761-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="11">
        <location>
            <begin position="8"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="10">
        <location>
            <begin position="205"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="8">
        <location>
            <begin position="16"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="8">
        <location>
            <begin position="42"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="8">
        <location>
            <begin position="63"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="8">
        <location>
            <begin position="123"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="8">
        <location>
            <begin position="153"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="16"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="63"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="123"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="295" mass="34314" checksum="8BE0454CEF9D45F4" modified="2004-07-05" version="1">MRTYMDFKSGFIAILGRPNVGKSTLLNALTQQKVAITSAKPQTTRHKIIGICHEPNAQYIFVDTPGINQYKHLLNQKMNNIAFQSIKDVDLILFLTDSFYHPKEETLLKMIFQTKKPVFLVINKIDRLKNKSQIDAIILSYLNHFSFQTVIPLSAIKAKNTTFLKENIYQNIKPGVAYYPQDMITDQKKELWIAEIIREKVLYYVHEEIPHASAVIIEKMEQKEHLLEIWGLILVERSSQKQILIGKAGSKLKQIGTHVRQDLNCHLQIKTHINLWVKVYPNWRNQKDLLSRFGY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-15" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPV1</accession>
    <name>YBEY_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ybeY</name>
        <name type="ordered locus">PAM_624</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPV1"/>
    <dbReference type="SMR" id="Q6YPV1"/>
    <dbReference type="STRING" id="262768.PAM_624"/>
    <dbReference type="EnsemblBacteria" id="BAD04709">
        <property type="protein sequence ID" value="BAD04709"/>
        <property type="gene ID" value="PAM_624"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_624"/>
    <dbReference type="eggNOG" id="COG0319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106710_3_0_14"/>
    <dbReference type="OMA" id="RMRIHPL"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46986">
        <property type="entry name" value="PTHR46986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000102500" description="Endoribonuclease YbeY">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <sequence length="146" mass="16948" checksum="32113D5FD4D388BE" modified="2004-07-05" version="1">MIIKIHNQTSFCITPFKSLLIKMFLPIKEKKLMHLIFVTNEKIQELNSFYRQKNYPTDVLSFPNDLTFFAGLEDNSLGDVFISFSKAQVQAQTAKHSLEREIAFLAVHGFLHLKGYQHRTEEEFQIMLALQEKILQNVGLNLDKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPV9</accession>
    <name>Q6YPV9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_616"/>
    <dbReference type="EnsemblBacteria" id="BAD04701">
        <property type="protein sequence ID" value="BAD04701"/>
        <property type="gene ID" value="PAM_616"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_616"/>
    <dbReference type="eggNOG" id="COG2812">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1617330_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="164" mass="19064" checksum="3979BAF12208FFF3" modified="2004-07-05" version="1">MISFAINILSNQDEPTKNTITNFWTNLKNRYSTHSYYKNVSEILDRGKIVALSQSQQMILVFEDEDAFELVLQKNIKQKALEILNNDTFAITDYIAFLKQDWQALETFYNKNHPHPNQESIAKFTATCNFDLDLYQIKATQPTKPAIIQLAYDFFGKDIVEIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPW2</accession>
    <name>Q6YPW2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylserine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pssA</name>
        <name evidence="2" type="ordered locus">PAM_613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_613"/>
    <dbReference type="EnsemblBacteria" id="BAD04698">
        <property type="protein sequence ID" value="BAD04698"/>
        <property type="gene ID" value="PAM_613"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_613"/>
    <dbReference type="eggNOG" id="COG1183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049944_4_0_14"/>
    <dbReference type="OMA" id="LIRLAYY"/>
    <dbReference type="OrthoDB" id="1232102at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-739-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="244" mass="28067" checksum="CB4F17F93C1584A8" modified="2004-07-05" version="1">MFLGFYNYTTYLTYLNLMSGFCGIGFGACGKYTSALICLLISGVCDMFDGVVSRTKKNRIHTEKSYGIQIDSLADIISFGVLPIFINYSLSFKGETSIIKEEFWLFALVWLFWGFYLLAALIRLAYYNVLAETQKYDSQSPSYFTGLPVTAAAILFPFLFLAKFICKTWDLKSLGFIEQRTTFFWFHFACMLLLTFLFLCKKIHFPKPKAKTTITIILLLALNFILFMLLKILLKYLLPMTITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPX0</accession>
    <name>Q6YPX0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mg-dependent DNase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tatD</name>
        <name evidence="1" type="ordered locus">PAM_605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_605"/>
    <dbReference type="EnsemblBacteria" id="BAD04690">
        <property type="protein sequence ID" value="BAD04690"/>
        <property type="gene ID" value="PAM_605"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_605"/>
    <dbReference type="eggNOG" id="COG0084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031506_4_0_14"/>
    <dbReference type="OMA" id="PNEAPRI"/>
    <dbReference type="OrthoDB" id="915852at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-730-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00010">
        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="255" mass="29329" checksum="2B6C3DA079185755" modified="2004-07-05" version="1">MLIDTHAHLNLKTYKNKLDDVFQKAWNNDVKKMIVIGMDEKTNQKAYEIANKYKEVMVAFGIHPCSDFSQETPESIIKYLNHQQTVAIGEIGLDLHHRQDNLAVQKKFFQAQVKIAIQYNLPIIIHARKSFEEIYQLLLPYRNQVRGVFHCLVFSLEEAKKALELGFYIGIGGVVTYPHAKVSHEIAKTIPLDKILLETDCPYLTPYPFQNETNEPYHIKLIAQKIAQLRNISLQCVATQTSNNVAKLFLNKNSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPX1</accession>
    <name>Q6YPX1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04689">
        <property type="protein sequence ID" value="BAD04689"/>
        <property type="gene ID" value="PAM_604"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_604"/>
    <dbReference type="HOGENOM" id="CLU_2070705_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="118" mass="14127" checksum="EF44CD167CEDA682" modified="2004-07-05" version="1">MVLNDPKVKNLFNKDPNKGKTIQNIDFGESIRPYFKACMYDDNISFNSKEKKTKIVCCSFVLVVILMILALFFNVELKKETLAKFLFYISLTYFICFYIYFTLYSYSVLWFLYVKFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPY7</accession>
    <name>Q6YPY7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC-type amino acid transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">artM</name>
        <name evidence="8" type="ordered locus">PAM_588</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_588"/>
    <dbReference type="EnsemblBacteria" id="BAD04673">
        <property type="protein sequence ID" value="BAD04673"/>
        <property type="gene ID" value="PAM_588"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_588"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_20_4_14"/>
    <dbReference type="OMA" id="MWAIFKG"/>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-711-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="520"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="549"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="361"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAD04673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="576" mass="66854" checksum="C234EDA34F73214E" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-07-10" modified="2022-05-25" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPY9</accession>
    <name>RS4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsD</name>
        <name type="ordered locus">PAM_586</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="frameshift">
            <sequence resource="EMBL-CDS" id="BAD04671" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04671.1"/>
        <property type="status" value="ALT_FRAME"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPY9"/>
    <dbReference type="SMR" id="Q6YPY9"/>
    <dbReference type="STRING" id="262768.PAM_586"/>
    <dbReference type="EnsemblBacteria" id="BAD04671">
        <property type="protein sequence ID" value="BAD04671"/>
        <property type="gene ID" value="PAM_586"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_586"/>
    <dbReference type="eggNOG" id="COG0522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092403_1_0_14"/>
    <dbReference type="OMA" id="NVVFRMG"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000293329" description="30S ribosomal protein S4">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="S4 RNA-binding" evidence="1">
        <location>
            <begin position="91"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="198" mass="23033" checksum="6935156B178ED05D" modified="2007-07-10" version="2">MSRYTGSLWKVSRRLNYSVSETGKELRKRAYGPGQHGQKKLKLSDYGLQLQEKQKLRFTYGVSEKQFRKTFDNASKLKGIHGEMFLVLLESRLDNVVYRLGFAKTRAQARQLANHGHILVDGKKVDIASYRLKPGQTVTLREKSKNLNIVQEAVNSKFVRADYVSLDKELVGKYVRYPQRNEFLPDINEQLIVEYYNR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-09-11" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPZ6</accession>
    <name>TSAD_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName>tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber>2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName>t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName>t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">tsaD</name>
        <name type="synonym">gcp</name>
        <name type="ordered locus">PAM_579</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="1">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPZ6"/>
    <dbReference type="SMR" id="Q6YPZ6"/>
    <dbReference type="STRING" id="262768.PAM_579"/>
    <dbReference type="EnsemblBacteria" id="BAD04664">
        <property type="protein sequence ID" value="BAD04664"/>
        <property type="gene ID" value="PAM_579"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_579"/>
    <dbReference type="eggNOG" id="COG0533">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023208_0_1_14"/>
    <dbReference type="OMA" id="NGSCERG"/>
    <dbReference type="OrthoDB" id="1257362at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-702-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000303464" description="tRNA N6-adenosine threonylcarbamoyltransferase">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="133"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="233" mass="25543" checksum="DEB2A7AF0E3582B1" modified="2004-07-05" version="1">MNILSIETSCDETSCAVTQNGKKVLSNVVFSQIKDHQIFGGVVPEIASRKHIQFMTLVLQQALKEANLTPQEIDLVAVTQGPGLVGSLLVGINAANVFAYTYQKPLLGVNHLLGHIYSAQIEHEINFPALVLLVSGGHTDLFYLTDHLQIKPLGTTLDDAVGEVYDKIAKNLNLPYPGGPLIDQLAQQGKDTYHLVRPYLKNDNLNFSFSGLKSTLVNLVMKQNLKDINIPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPZ8</accession>
    <name>Q6YPZ8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_577"/>
    <dbReference type="EnsemblBacteria" id="BAD04662">
        <property type="protein sequence ID" value="BAD04662"/>
        <property type="gene ID" value="PAM_577"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_577"/>
    <dbReference type="HOGENOM" id="CLU_1633704_0_0_14"/>
    <dbReference type="OMA" id="NNYIMAM"/>
    <dbReference type="OrthoDB" id="2175510at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-697-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="162" mass="18791" checksum="61214999E45DA6ED" modified="2004-07-05" version="1">MFKLQNQFKIIRVFLFTFLGFLIINNNQVMAMGNKNSNNNSEISNDKEYALYIQAEIAIKSELTNLQLNNAKKSELLHKQQFITTEIEKYNKRQNNNQLSTTYGEQPESSRRNISSAINDDDENELSDDELQPMNLIKNNSKCPIDQPESSKKNIIKNKKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPZ9</accession>
    <name>Q6YPZ9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_576"/>
    <dbReference type="EnsemblBacteria" id="BAD04661">
        <property type="protein sequence ID" value="BAD04661"/>
        <property type="gene ID" value="PAM_576"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_576"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1065265_0_0_14"/>
    <dbReference type="OMA" id="NIRNFAQ"/>
    <dbReference type="OrthoDB" id="1844893at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-696-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="269" mass="31485" checksum="7BA817C0231B0E86" modified="2004-07-05" version="1">MFKLKKHLLLFNIILFIILGLFLINNSNQVRAMEGLFHEEIQEITETESEENEEITHNISKTNIISKEKFVSLHEIGHAVVAFELSQRHREYPNLIKLKGIELKQDDETIDGSTDFSFDRDNLFGHLFALSVYYGGLEAEKTIKTPIEEIKNRGQHDEQDIEKTAQYITERGWFLGDFYLSTDSLEIRKNKIKNIAQTKTQEIIQQYQEFLSPLADELLQREVIGIEEFQKLLKELIIQRKPSQKPEQLETIEKSNYNHKKTKCDCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ03</accession>
    <name>Q6YQ03_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA primase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dnaG</name>
        <name evidence="9" type="ordered locus">PAM_572</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_572"/>
    <dbReference type="EnsemblBacteria" id="BAD04657">
        <property type="protein sequence ID" value="BAD04657"/>
        <property type="gene ID" value="PAM_572"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_572"/>
    <dbReference type="eggNOG" id="COG0358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_620870_0_0_14"/>
    <dbReference type="OrthoDB" id="1071997at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-691-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0639">Primosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="302"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="441" mass="52537" checksum="4B1B09B3E9D73E71" modified="2004-07-05" version="1">MNYQDKIKHIQTHFPMSVLLKKLNIIPSNFNPKYRFPCPLHQGNNPTCCHFTSTNKIHCWKCVRDYDIIDVYMTIRQIKSFYEAIQRIEGFMNSFEFKTLSQQEKEITKIITNPFPQPYHPMKPKQPVDEQEINIKKKQLFKDISPLFNQIRDYYHYLLISNRNNESQPGLTYLTQKRKLTLETIKEFQLGYAPLSDKPLSFRLVNYCQKKNIDTTKLVEYGFIKEKTNQQNKKYYHDTFHGSIIIPIENGYHQTFHFYQNHFREVSYFQPKYQALTNFSQTPTFHFSYRFFEALPYIKQTKTIIIHEGFFDVISCWQNNIKNVVGLICVTQLLSQSQLEILKKEKIKVIIALDNDETGRKRSEALGEQLKETNILYEIRHILPPYNQTCKDVDDLLRQYGKEAYQKCFLDPYLSYEEAKKKIIVDLVVHFFGEDKVEIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ11</accession>
    <name>Q6YQ11_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_564</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_564"/>
    <dbReference type="EnsemblBacteria" id="BAD04649">
        <property type="protein sequence ID" value="BAD04649"/>
        <property type="gene ID" value="PAM_564"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_564"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OMA" id="HDPEKQY"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-678-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="111" mass="12949" checksum="21BFACB933383817" modified="2004-07-05" version="1">MLNNIQLIGRITHDPEKQYINSNNEQIPKIDFQLAVNQTKDKVQYIPCVVFRTQAENFHKYLHKGSKIYLEGTLSIQKYTNNEGQNKTNTKVIVHKVIFLDNKSQTDNLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ25</accession>
    <name>Q6YQ25_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replicative DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dnaB</name>
        <name evidence="2" type="ordered locus">PAM_550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_550"/>
    <dbReference type="EnsemblBacteria" id="BAD04635">
        <property type="protein sequence ID" value="BAD04635"/>
        <property type="gene ID" value="PAM_550"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_550"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_546093_0_0_14"/>
    <dbReference type="OMA" id="TKNLYYQ"/>
    <dbReference type="OrthoDB" id="284055at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-660-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="1">
        <location>
            <begin position="190"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="498" mass="58819" checksum="73CE454D0C20B6DA" modified="2004-07-05" version="1">MLTNEQKALKQLINYIEQGQWEKLNLYYQIINPKNLLNPKNKKIFTTLKYLFLEKQTTHPWDKIKSQTEIIKELLTYLQTNFQQDNFTKESLSFLNNDFSKENNLDFLDNLKHTYTQEKLFQQLLKIISPSFETQDPYTKNLYYQEIFDKLRNFISLIPQKNDKTLFNLNQMVFLHPEFFDTDNQAKQKIQEEYYHLSEIFKGLNQSTKGLKKGQIITIGGYTGLGKTTFVYNLLLDIAKTKHQESSHYPHILVFSYEITMEENLSRLLAHQTQIPLDIILDKNFEDDNITPLKYTERMKIAKQFFANINLSFSYDKSKNIDYIIDLVYRLYLEKQVEIIVIDHLQITKASNRLENDRLAIDEIMTKLKQLAMELNIVIIILSQFSRDTYSNYQGKSPEITALKGSGGIETNSDIVLMMSEFQPKLSKDQEKPLNIYNQNCNQLYLVSKNNESQKIIELSIKKNRSGTKKTLIYHFEMTTQTFQEIGYVLPYQIETYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-01-19" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ27</accession>
    <name>Q6YQ27_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_548"/>
    <dbReference type="EnsemblBacteria" id="BAD04633">
        <property type="protein sequence ID" value="BAD04633"/>
        <property type="gene ID" value="PAM_548"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_548"/>
    <dbReference type="HOGENOM" id="CLU_1609154_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="165" mass="19521" checksum="EA44166255192FC6" modified="2004-07-05" version="1">MIYYKIPIKQQQTYYFFLYDLFKNKINNMNHAHSIIRPKIDKYFNKMTKINLKEKIKMKNDLNKGIRIGGWNTKTTPTDLDQIKLFLQTLKQDLINLTIITHSKKKNTYQEANYRPKNQTLFVDPQILDEIKQTKITLINDNFSSSNSKLLLSDLPPLKNQNTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ45</accession>
    <name>Q6YQ45_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_530"/>
    <dbReference type="EnsemblBacteria" id="BAD04615">
        <property type="protein sequence ID" value="BAD04615"/>
        <property type="gene ID" value="PAM_530"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_530"/>
    <dbReference type="HOGENOM" id="CLU_2024369_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="122" mass="14677" checksum="33F301E5EAAEE915" modified="2004-07-05" version="1">MMILKMIFSFNFLKYLISFDFKDFFYLLYSIFYSIFFTKSSFLFGFNVGWNINFINIYNVIKTIFIFMWEQLTTLIYPLKLFSSLFDFLMQILKIFIDVFGSIIGYIKSSITTSYWSKINGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ50</accession>
    <name>Q6YQ50_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_525"/>
    <dbReference type="EnsemblBacteria" id="BAD04610">
        <property type="protein sequence ID" value="BAD04610"/>
        <property type="gene ID" value="PAM_525"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_525"/>
    <dbReference type="HOGENOM" id="CLU_1319854_0_0_14"/>
    <dbReference type="OMA" id="NYQNESK"/>
    <dbReference type="OrthoDB" id="1617013at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-629-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="212" mass="25029" checksum="8872E0E0931D841B" modified="2004-07-05" version="1">MNDTSQEIRIGGWNTKTTPNDLTQIKNFLKILKEDLINLTIISHSKKKNTYQEANYRPKNQTLFVDLQILEEIKQTKITLINDNFSSSNSKPLLSDLTPLKSQKNPLKHLYPLFQINYQNESKNNIKELIGKIDVNKLETLQLYQLDSQKRDKYNKTIKTNYKKGLNIIYYHQEDLKYIHFFLTKAKQGYRVKKLRSGYLSNLNKKELKTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="117" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ63</accession>
    <name>Q6YQ63_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_512</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_512"/>
    <dbReference type="EnsemblBacteria" id="BAD04597">
        <property type="protein sequence ID" value="BAD04597"/>
        <property type="gene ID" value="PAM_512"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_512"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-614-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="109" mass="12709" checksum="C0451547B121F1F4" modified="2004-07-05" version="1">MLNKVQLIGRLSHDLEKQYINSNNEQIPKIDFQLAVNLKEITQFIPCVAFRKQAENMKKYLHKGSKIYLEGILSIQKYTNNEGQIKTNTKVILQNVIFLDNKPQENLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ81</accession>
    <name>Q6YQ81_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type amino acid transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">artM</name>
        <name evidence="6" type="ordered locus">PAM_494</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_494"/>
    <dbReference type="EnsemblBacteria" id="BAD04579">
        <property type="protein sequence ID" value="BAD04579"/>
        <property type="gene ID" value="PAM_494"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_494"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2410385_0_0_14"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-596-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="92" mass="10697" checksum="016634B9305DC682" modified="2004-07-05" version="1">MLEFIILIWLFKKTSLSFLATPFITTLLVISLNTIANLTNLFMHNIKMLDKGQIEAAYSLGMNQKQVFKYILFEQGLQRTKPFILATIYSKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ89</accession>
    <name>Q6YQ89_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04571">
        <property type="protein sequence ID" value="BAD04571"/>
        <property type="gene ID" value="PAM_486"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_486"/>
    <dbReference type="HOGENOM" id="CLU_1420194_0_0_14"/>
    <dbReference type="OMA" id="DYWENIE"/>
    <dbReference type="OrthoDB" id="2057040at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-572-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5004283513" evidence="2">
        <location>
            <begin position="36"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="191" mass="21636" checksum="39EA5EF0D378F863" modified="2004-07-05" version="1">MLKKSVKNNYLIFLILITFVFISCFLSAFIPSAFADDKKDPKEKTTPVSESPQSQGPKLEVVDYDLVQSFQDSLNTKTSLSCSCVAYKMKLYLKAKNPKSQSEVGTLVEFLYSSVLGVDYWENIEVDSFDKCTYDDDNTKANLISILTMIFKEAKTLLSNVDESCLLLVEQLNDKLFASWIQDTVKSLWAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ92</accession>
    <name>Q6YQ92_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_483"/>
    <dbReference type="EnsemblBacteria" id="BAD04568">
        <property type="protein sequence ID" value="BAD04568"/>
        <property type="gene ID" value="PAM_483"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_483"/>
    <dbReference type="HOGENOM" id="CLU_1298724_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="164"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="212" mass="25314" checksum="AA92BA19C467333E" modified="2004-07-05" version="1">MFIFWKLIIILKIYYFYIFTIKNNFLFRIRRKAVVLKVTQQKQKQLLCLVVIISGFLFVLLAILIIDPFGWFKKTKTLPQTHLETTYNPPYPFVAPETFSLDYDKLNVEQTINKVNDILEETSLEENNIKISKLDNEIIKNNFNEIPKNKLQTDYLERKRKDYIEDKQAQNKEKIENLTTEKNQKVNNKDELHNQIIPLKNQELEAKSKKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ93</accession>
    <name>Q6YQ93_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_482"/>
    <dbReference type="EnsemblBacteria" id="BAD04567">
        <property type="protein sequence ID" value="BAD04567"/>
        <property type="gene ID" value="PAM_482"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_482"/>
    <dbReference type="HOGENOM" id="CLU_1720489_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="152" mass="17787" checksum="5220C343126D5E96" modified="2004-07-05" version="1">MQGQITNLGNQIQNEPSSTSQNYSESNLEEIRRNNSDIQERIGNIQSAVQSNQTQINNITNNELPPIQTQITNLQENLSPLVKEHKHLIEEIKELESQIKCLNKFNKKLESFDIYQYSEKPQNHFKKCQTCQQWKNCINSEFKTTFYPVVKK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="115" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQA1</accession>
    <name>SECA_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="1">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">secA</name>
        <name type="ordered locus">PAM_474</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + cellular proteinSide 1 = ADP + phosphate + cellular proteinSide 2.</text>
            <dbReference type="EC" id="7.4.2.8"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_474"/>
    <dbReference type="EnsemblBacteria" id="BAD04559">
        <property type="protein sequence ID" value="BAD04559"/>
        <property type="gene ID" value="PAM_474"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_474"/>
    <dbReference type="eggNOG" id="COG0653">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005314_3_0_14"/>
    <dbReference type="OMA" id="MVHYDVQ"/>
    <dbReference type="OrthoDB" id="212453at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-559-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008564">
        <property type="term" value="F:protein-exporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="SSF81886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0811">Translocation</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000320878" description="Protein translocase subunit SecA">
        <location>
            <begin position="1"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="806"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="103"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="835" mass="95751" checksum="30499DE13B3210F7" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-12-21" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQA5</accession>
    <name>RL19_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplS</name>
        <name type="ordered locus">PAM_470</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQA5"/>
    <dbReference type="SMR" id="Q6YQA5"/>
    <dbReference type="STRING" id="262768.PAM_470"/>
    <dbReference type="EnsemblBacteria" id="BAD04555">
        <property type="protein sequence ID" value="BAD04555"/>
        <property type="gene ID" value="PAM_470"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_470"/>
    <dbReference type="eggNOG" id="COG0335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103507_2_2_14"/>
    <dbReference type="OMA" id="TITVYYE"/>
    <dbReference type="OrthoDB" id="1698718at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-555-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000163500" description="50S ribosomal protein L19">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <sequence length="118" mass="13624" checksum="9DB20F4C9726423E" modified="2004-07-05" version="1">MSQLKGQNLIESVNQHQLKDVPFFKPGDTVKVFIKIDEGNRKRVQIFEGLVIKRQGRLVTETFTVRKIFAGVGIELTFPVHSPTNEKIEVVRRGIVRRAKLHYVRNLSSKASRIKEQR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-05-16" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQA6</accession>
    <name>SYY_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="1">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tyrS</name>
        <name type="ordered locus">PAM_469</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQA6"/>
    <dbReference type="SMR" id="Q6YQA6"/>
    <dbReference type="STRING" id="262768.PAM_469"/>
    <dbReference type="EnsemblBacteria" id="BAD04554">
        <property type="protein sequence ID" value="BAD04554"/>
        <property type="gene ID" value="PAM_469"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_469"/>
    <dbReference type="eggNOG" id="COG0162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024003_0_2_14"/>
    <dbReference type="OMA" id="YMMAKDS"/>
    <dbReference type="OrthoDB" id="402899at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-554-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02006">
        <property type="entry name" value="Tyr_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024107">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <feature type="chain" id="PRO_0000234746" description="Tyrosine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="S4 RNA-binding" evidence="1">
        <location>
            <begin position="347"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region">
        <location>
            <begin position="225"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02006"/>
        </source>
    </evidence>
    <sequence length="413" mass="47449" checksum="CB0CD2413A9FB28B" modified="2004-07-05" version="1">MSFYEELKWRNLIKDCSNETQVKELLDNNQVKFYCGFDPTSHSLTVGHLVQITMILLMQRQGHLPVILVGGATGLIGDPKETEERKLLSLENSLQNAKSIECQLKNILLNKQVEFVNNYQWLSQIDIISFLRNYGKLFNINYMLSKHAVAKRLASGISFTEFSYMILQSLDFHHLYKNHKVRLQLGGSDQWGNITSGLELIRKLEKKSDALGISTPLLLNSDGTKFGKSEKGVLWVNPSMTSPYEIYQYFLNVSDKEVINYLKMLTLIPKQEILELEKNTLENPQQRLAQKALTQNIITLIHSSDILQECIKTNQILFSNAKKESFQEKDFILLQKTLFCHSTKEDILLVDALVQTKLATSKSEAREFIKDNTIKLFNQKIKSLDFAITKKNTLFDKYVLLKKGKKNNALIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQB9</accession>
    <name>Q6YQB9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type amino acid transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">artM</name>
        <name evidence="9" type="ordered locus">PAM_456</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_456"/>
    <dbReference type="EnsemblBacteria" id="BAD04541">
        <property type="protein sequence ID" value="BAD04541"/>
        <property type="gene ID" value="PAM_456"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_456"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_20_3_14"/>
    <dbReference type="OMA" id="WVEKRTR"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-540-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018313">
        <property type="entry name" value="SBP_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01039">
        <property type="entry name" value="SBP_BACTERIAL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="384"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="597" mass="68098" checksum="38F5DDDC763DF426" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQC4</accession>
    <name>Q6YQC4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04536">
        <property type="protein sequence ID" value="BAD04536"/>
        <property type="gene ID" value="PAM_451"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_451"/>
    <dbReference type="HOGENOM" id="CLU_2082427_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-533-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="117" mass="13568" checksum="066DDD688A53B637" modified="2004-07-05" version="1">MANAPLDIKNKMDDIKQEIERKGIEPTQEDGLNFVKHIMQSFLLPKLKNKLSPKAYNEYKQQIDEALERIKAATFQNQQLPEMIKIDDGIKHNNDLINNIDKDKSFIDKGKNESENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQF4</accession>
    <name>Q6YQF4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_419"/>
    <dbReference type="EnsemblBacteria" id="BAD04504">
        <property type="protein sequence ID" value="BAD04504"/>
        <property type="gene ID" value="PAM_419"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_419"/>
    <dbReference type="HOGENOM" id="CLU_1052309_0_0_14"/>
    <dbReference type="OMA" id="KNTIFQT"/>
    <dbReference type="OrthoDB" id="1341993at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-505-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="270" mass="31916" checksum="48BEB2BB4FB1334B" modified="2004-07-05" version="1">MKIQKSPKNIINKKNILTKRYFFNLFLLLTMIIATTGGIGYYFFNHSKQPVYEIIVNKNTIFQTNNNDCFDDYNDKIKQLNEEITIKNEELKEPSLSPQEKQVIEQIVKLKTQQKKELQIDLFLKKFLKKSEEEILEIDNKIKTTNQLEEKHSLTETKLLKEKEIIKYQKLLKDKELNIVNITQLDQKLVQPDLNSATKTALENQKTQNQNNIKNINEQITKKVNLINLKTKKNVIEQELQDPQISSELKQYLIKYKENTEKQITNLETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQG7</accession>
    <name>Q6YQG7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tra5</name>
        <name evidence="2" type="ordered locus">PAM_406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_406"/>
    <dbReference type="EnsemblBacteria" id="BAD04491">
        <property type="protein sequence ID" value="BAD04491"/>
        <property type="gene ID" value="PAM_406"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_406"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_21_0_14"/>
    <dbReference type="OMA" id="EECQLIM"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_21" evidence="1">
        <location>
            <begin position="76"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="202" mass="24556" checksum="AFEFC71937D12BE8" modified="2004-07-05" version="1">MKLEKLHQKVKLLQKIIEKIKKIDKKIVFNLVNQFNQTLNLTTILKTIQIKRSTYYWLKVKNKIKEKEEKYLLQQKRIKALCLHYQYFYGHRKITTLYHKTFNELITKKKVYTIMRKNSIFCRLRIKKNKYYYNNNLKSKLKVVDNLINQDFISKTPLQKLFTDVTYFKTPKGFLYFSCIIDSFNNQIIAFHTSNHQNKDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="103" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQI0</accession>
    <name>Q6YQI0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflB</name>
        <name evidence="5" type="ordered locus">PAM_393</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_393"/>
    <dbReference type="EnsemblBacteria" id="BAD04478">
        <property type="protein sequence ID" value="BAD04478"/>
        <property type="gene ID" value="PAM_393"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_393"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="OMA" id="PLANIKH"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-472-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="282"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="129"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="549"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="764" mass="90006" checksum="F196BC453CC2FE7E" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQJ5</accession>
    <name>Q6YQJ5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_378"/>
    <dbReference type="EnsemblBacteria" id="BAD04463">
        <property type="protein sequence ID" value="BAD04463"/>
        <property type="gene ID" value="PAM_378"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_378"/>
    <dbReference type="HOGENOM" id="CLU_175522_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-452-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="112" mass="13243" checksum="3ADFFBA19FA8556A" modified="2004-07-05" version="1">MFNIKKIIKWFFIILGVFLFLIIGFIGFMVLTEKKINKLPKEEIPILKETAFKNIEEWYDNNNKCTMIKDKYTFDGLNGVGYYQEQLQEKKVVITIFRSLKNASKPKKNPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQJ9</accession>
    <name>Q6YQJ9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thymidylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tmk</name>
        <name evidence="2" type="ordered locus">PAM_374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_374"/>
    <dbReference type="EnsemblBacteria" id="BAD04459">
        <property type="protein sequence ID" value="BAD04459"/>
        <property type="gene ID" value="PAM_374"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_374"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1946601_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="1">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="145" mass="16855" checksum="D45D30A748684DFE" modified="2004-07-05" version="1">MKVFFMPKLKIKGEKMIKLIVFEGLDGSGKTSLINSLQPHLKNPYQLYQGLGSSSLGKEIRGLFLNFQQVDYLTRFYLSLANMAQIQAELIVSQLKNNQLIILDRWLPSTYAYQLFPFSKEKKQLLLLKKIFKLNHETILKNPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQK8</accession>
    <name>Q6YQK8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial nucleoid DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">himA</name>
        <name evidence="2" type="ordered locus">PAM_325</name>
        <name evidence="3" type="ordered locus">PAM_365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_325"/>
    <dbReference type="EnsemblBacteria" id="BAD04410">
        <property type="protein sequence ID" value="BAD04410"/>
        <property type="gene ID" value="PAM_325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04450">
        <property type="protein sequence ID" value="BAD04450"/>
        <property type="gene ID" value="PAM_365"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_325"/>
    <dbReference type="KEGG" id="poy:PAM_365"/>
    <dbReference type="eggNOG" id="COG0776">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105066_3_3_14"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-386-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-434-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="96" mass="11169" checksum="F21865EF3D0E3AC8" modified="2004-07-05" version="1">MTKKELIKKIALSNKTSVTKTEEFYHIFEKTLIEAITNNEEVVLFPKIGKFKLKSRKSYIGRNPKTKKKLKIPKKTVVTFKLSKSIKDKTKTLILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="129" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQK9</accession>
    <name>Q6YQK9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_324</name>
        <name evidence="6" type="ordered locus">PAM_364</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">Onion yellows</strain>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_324"/>
    <dbReference type="EnsemblBacteria" id="BAD04409">
        <property type="protein sequence ID" value="BAD04409"/>
        <property type="gene ID" value="PAM_324"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04449">
        <property type="protein sequence ID" value="BAD04449"/>
        <property type="gene ID" value="PAM_364"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_324"/>
    <dbReference type="KEGG" id="poy:PAM_364"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OMA" id="MNQINIV"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-385-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-433-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="109" mass="12528" checksum="B73FF2B3A6A2CF82" modified="2004-07-05" version="1">MLNKVQLIGRISHDLEKQYINSNNEQIPKIDFQLAVNLKDKTQFIPCVVFSTQTENMNKFLHKGSKIYVEGALAIQKYTTNDGENKTTTKVIIQNVIFLDNKPQETLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="126" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQL4</accession>
    <name>Q6YQL4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_319</name>
        <name evidence="6" type="ordered locus">PAM_359</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">Onion yellows</strain>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_319"/>
    <dbReference type="EnsemblBacteria" id="BAD04404">
        <property type="protein sequence ID" value="BAD04404"/>
        <property type="gene ID" value="PAM_319"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04444">
        <property type="protein sequence ID" value="BAD04444"/>
        <property type="gene ID" value="PAM_359"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_319"/>
    <dbReference type="KEGG" id="poy:PAM_359"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-380-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-428-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="109" mass="12706" checksum="AACD0F483C219329" modified="2004-07-05" version="1">MLNKVQLIGRISHDLEKQYINSNNEQIPKIDFQLAVNLKEITQFIPCVAFRKKAENMKKYLHKGSKIYLEGLLSIQKYTNNEGQTKINTKVILQNVIFLDNKPQETLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQM1</accession>
    <name>Q6YQM1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_352"/>
    <dbReference type="EnsemblBacteria" id="BAD04437">
        <property type="protein sequence ID" value="BAD04437"/>
        <property type="gene ID" value="PAM_352"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_352"/>
    <dbReference type="HOGENOM" id="CLU_1843094_0_0_14"/>
    <dbReference type="OMA" id="DNNQEHK"/>
    <dbReference type="OrthoDB" id="2051611at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-420-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="157" mass="18492" checksum="0C57500B211B01E0" modified="2004-07-05" version="1">MMDIQQTIINVVESKVFISFTSFIFGIFIYWLYFYIKELKSKYDFSDELRDIVNHYLKKGKISISEYGALVRLMANMGNYLGIYRKHVETMIKEFGEHGGLNFSEGIFDEKDNNQEHKENNNNLDEILKENLKLKNQLNNIKNPLIAESIDDTENDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQM8</accession>
    <name>Q6YQM8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YqaJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04430">
        <property type="protein sequence ID" value="BAD04430"/>
        <property type="gene ID" value="PAM_345"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_345"/>
    <dbReference type="eggNOG" id="COG5377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1209247_0_0_14"/>
    <dbReference type="OMA" id="CPYRDEN"/>
    <dbReference type="OrthoDB" id="1563636at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-410-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017482">
        <property type="entry name" value="Phage_endonuclease_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03033">
        <property type="entry name" value="phage_rel_nuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ" evidence="1">
        <location>
            <begin position="11"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="209" mass="24956" checksum="26F0AAF8C9087D02" modified="2004-07-05" version="1">MRIKLSQRTKEWYQHRKKYINASEIGSITGKDKFRTLEQLVHDKLFGTTFTSNKYTEHGNKTEPLARTFFEKTTNLNFPDTIFTDDEVKMFSASLDGYNQQTNTLLEIKCPYRDENNNISTSWNGFFSYQEVPINYWAQIQCQLYCSQAKFAYFLVYFNDNDYHVVRIYLDNNFITKMIQDSKQYLELLSKTKQELSQTTYLKRLSKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="108" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQQ7</accession>
    <name>Q6YQQ7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflB</name>
        <name evidence="5" type="ordered locus">PAM_316</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_316"/>
    <dbReference type="EnsemblBacteria" id="BAD04401">
        <property type="protein sequence ID" value="BAD04401"/>
        <property type="gene ID" value="PAM_316"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_316"/>
    <dbReference type="eggNOG" id="COG0465">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020918_0_0_14"/>
    <dbReference type="OrthoDB" id="874197at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-376-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="282"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="115"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="457" mass="52846" checksum="7D5F97252FF84FC6" modified="2004-07-05" version="1">MTLNKKIYLSLIGLLSLGLLVLLIFGITHSRLPTKNPTLTKRPSLTQQQEIENQIKLEQAKIQELQQKDHQLKTQIEENVKTLTDIITKIKTLQTELTNNPQLPSTIKTQKQQQLTELKNQQQTQQTLVNNLIEQRKALNQNQKEKQKELEKLAQEKAQLQTQENLQQQISHLNQALNYVEANQKRIEELKTQKEYRKNQTELKNLNDFQLFLTDQKLAFEKQKKNLQTQLNNLKENKPLPNTKKQVTFKDVYGMESEKEELEDLLTYFQTNQSLINFDQVRPKGYLLYGPPGTGKTFLIKALCGEANVHFINLIPSKFRQKYIGEGEKEVEKVWQEAENHDKTIIFIDEIEGLENRNDSNISSGGVNVINTLLDKLDGFNSSNKKIVLMGATNNLHKIDTALRSRFSKEIYIGNLKNSEIEGYLKHIIVPYQISYHTFLALKDITQLCQGVFVGDY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-04-26" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQR9</accession>
    <name>YQGF_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">PAM_304</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YqgF nuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQR9"/>
    <dbReference type="SMR" id="Q6YQR9"/>
    <dbReference type="STRING" id="262768.PAM_304"/>
    <dbReference type="EnsemblBacteria" id="BAD04389">
        <property type="protein sequence ID" value="BAD04389"/>
        <property type="gene ID" value="PAM_304"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_304"/>
    <dbReference type="eggNOG" id="COG0816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098240_2_0_14"/>
    <dbReference type="OMA" id="VKWDERF"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-362-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="chain" id="PRO_0000172108" description="Putative pre-16S rRNA nuclease">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <sequence length="151" mass="17331" checksum="9F0DFE227A12D4AB" modified="2004-07-05" version="1">MLKCQNNASLGLDLGEKTLGIALSQTGIIAQNLKTIFFATHKYDRLIAPLQEIIFQYQIKTIVLGYPKHMNNDIGIKAKISSDFKKTLENKFEQVKVILWDERLSTVQAIQMLKTNNKKKGKILQMKDEIAATIILQNYLDYIKLHTNKEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQS4</accession>
    <name>Q6YQS4_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N6-adenine-specific methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_299"/>
    <dbReference type="EnsemblBacteria" id="BAD04384">
        <property type="protein sequence ID" value="BAD04384"/>
        <property type="gene ID" value="PAM_299"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_299"/>
    <dbReference type="eggNOG" id="COG0742">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075826_0_0_14"/>
    <dbReference type="OMA" id="FNWLMPY"/>
    <dbReference type="OrthoDB" id="1827334at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-357-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="186" mass="21532" checksum="2933DDB8E2C9E8CB" modified="2004-07-05" version="1">MTKTTIIIGGKFKGHKIKLVPSPHTKATSSLVKESLFNTLGASFQNKIFLDLFAGNGSYGFEALSRDAKQAYFVDASLKAFQTLKENHQKLKLDLEQSIIFYGHFIQALKKFQKANLIFDFIILDPPYFKDFYLPAFEYLDKLTHQNSIIICELHRKIVLPTQIKEFVLQKEKQYGNKKIQFYQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQT5</accession>
    <name>Q6YQT5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04373">
        <property type="protein sequence ID" value="BAD04373"/>
        <property type="gene ID" value="PAM_288"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_288"/>
    <dbReference type="HOGENOM" id="CLU_686332_0_0_14"/>
    <dbReference type="OMA" id="KANNCYS"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="404" mass="47018" checksum="E25465EDA2C8371B" modified="2004-07-05" version="1">MKIPSFKKNIIIVIIIFSILLIIFGWLGWQNNFFALEASQNSTKNTSLSSKNFNYNDLQDLPKNQNEKIEEQAPESKENNLDNPNQKGKKTLYPQITEIEENEEIKETPKYRPKATPKPNQNNNTQTIKKNPHLQKAKNKRKVMQKKLVYQNQKIIDLKEQILLLENEKNKPKELDNQFSDQIKPQLESQIQGMNIYNVYLGKKSDKDMALEWLRKNFSNQHYQINFSYGLYNSQIIQSTVFFDSRIKEPPPKNLLLVYFDGGTRDKANNCYSLEALKTLGNGAQNMYILWQDESPFNDKNFIQNNFCTDLIYEKGSFLGGPSYLNVKHIALKNINTNEIIATFPVKCQIEVPCSLDGLDLELKFPFYNYKIEGLLSNTHIKSLRKINVYSKHTGQSKTLYYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-12-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQT7</accession>
    <name>Q6YQT7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Malate/citrate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">citS</name>
        <name evidence="2" type="ordered locus">PAM_286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_286"/>
    <dbReference type="EnsemblBacteria" id="BAD04371">
        <property type="protein sequence ID" value="BAD04371"/>
        <property type="gene ID" value="PAM_286"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_286"/>
    <dbReference type="eggNOG" id="COG3493">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041211_0_1_14"/>
    <dbReference type="OMA" id="IINACHS"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008514">
        <property type="term" value="F:organic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004679">
        <property type="entry name" value="2-OHcarboxylate_transport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40033">
        <property type="entry name" value="PTHR40033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03390">
        <property type="entry name" value="2HCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="381" mass="42208" checksum="4B15F901A849AF3E" modified="2004-07-05" version="1">MLCIFVPSYLVYKGWIPQDLANKCNENFFSTKTPNNHLGSDFANFFITCVIAGSILSVDRNLLKRSLSKFLPLTLIVCLVAILSVGFVGFLFNYQKPEGFSTQGSFLDSIFYVAVPLTNGGTNLGINGFANGIYKDAFPQLDQKTIRTAIIVPLIMARCLSILFAGLMYVIFDKTKFSGKGKLEYKNNKLTPKPTEKKTPLEYKNIGMGLTMIFVLFSLSGLLNKLLWGYLESLVYFILFLILIRVFNLLSQENQSHISQAGQVISKNFTTPILAGLGMTVKWQQLMGGIKQIPVLTMVLTALLVVVLVSFVLAKALGFYPFETSLTAGLGALSVGGTGHLGIMSISKRDNLLPFIMIATRIIGPIIYTLAYFLFKFFYMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQU5</accession>
    <name>Q6YQU5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome biogenesis GTPase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">PAM_278</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_278"/>
    <dbReference type="EnsemblBacteria" id="BAD04363">
        <property type="protein sequence ID" value="BAD04363"/>
        <property type="gene ID" value="PAM_278"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_278"/>
    <dbReference type="eggNOG" id="COG1161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011106_1_0_14"/>
    <dbReference type="OMA" id="GVLWPKF"/>
    <dbReference type="OrthoDB" id="1083771at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-336-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019991">
        <property type="entry name" value="GTP-bd_ribosome_bgen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016478">
        <property type="entry name" value="GTPase_MTG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006230">
        <property type="entry name" value="MG442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03596">
        <property type="entry name" value="GTPase_YlqF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="3">
        <location>
            <begin position="12"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="135"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006230-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="295" mass="33607" checksum="D31AF0A6CEAA69D2" modified="2004-07-05" version="1">MKAFNWFPGHMKKTFDQIKNNLSLVDIVLVILDARIPLSSLNSQIFSLINQRQKPLLILLNKFSLTDPCKINNFIANYHKKQIPVLTIDAIKSPKLQEIYQKALTTIKAKNPLFKSRRIATQTPNIKAMIVGTPNVGKSTLINSFAQKKVLKTANLAGTTKRIQWIDIAKPNIQFLDTPGVLWHNFSDPRISLALALAGCFKDSILPLEKLGIHALCYLIKHYGTNLQKRFNLDQNDLSNPNLVDIIGQKRNIYTKNQKVDQSRVYQMLLQEIRQGNLGKLNFDLDVLSLFEKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQU9</accession>
    <name>Q6YQU9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_274"/>
    <dbReference type="EnsemblBacteria" id="BAD04359">
        <property type="protein sequence ID" value="BAD04359"/>
        <property type="gene ID" value="PAM_274"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_274"/>
    <dbReference type="eggNOG" id="COG1692">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2918148_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005235">
        <property type="entry name" value="YmdB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36303">
        <property type="entry name" value="PTHR36303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13277">
        <property type="entry name" value="YmdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="61" mass="6939" checksum="DD535DB7644931BA" modified="2004-07-05" version="1">MDFHAEATSEKIALTHYFDGRIDAIVGTHTHVQTNDERLFPHNTLYISDAGMTGAQGRRHW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-06-27" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQW2</accession>
    <name>RPOC_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="1">RNAP subunit beta'</shortName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpoC</name>
        <name type="ordered locus">PAM_261</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 Zn(2+) ion per subunit; 2 are expected compared to other organisms.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQW2"/>
    <dbReference type="SMR" id="Q6YQW2"/>
    <dbReference type="STRING" id="262768.PAM_261"/>
    <dbReference type="PRIDE" id="Q6YQW2"/>
    <dbReference type="EnsemblBacteria" id="BAD04346">
        <property type="protein sequence ID" value="BAD04346"/>
        <property type="gene ID" value="PAM_261"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_261"/>
    <dbReference type="eggNOG" id="COG0086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_3_0_14"/>
    <dbReference type="OMA" id="YRNIRVE"/>
    <dbReference type="OrthoDB" id="4421at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-318-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01322">
        <property type="entry name" value="RNApol_bact_RpoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012754">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02386">
        <property type="entry name" value="rpoC_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000240813" description="DNA-directed RNA polymerase subunit beta'">
        <location>
            <begin position="1"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Unknown">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="DNA-directed RNA polymerase subunit beta'">
        <location>
            <begin position="118"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="580"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="582"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="1353" mass="153591" checksum="D605F128CD5E5EBE" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="118" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQW8</accession>
    <name>Q6YQW8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">nusG</name>
        <name evidence="10" type="ordered locus">PAM_255</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_255"/>
    <dbReference type="EnsemblBacteria" id="BAD04340">
        <property type="protein sequence ID" value="BAD04340"/>
        <property type="gene ID" value="PAM_255"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_255"/>
    <dbReference type="eggNOG" id="COG0250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067287_1_1_14"/>
    <dbReference type="OMA" id="DGPFNGF"/>
    <dbReference type="OrthoDB" id="2027986at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-312-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015869">
        <property type="entry name" value="Transcrpt_antiterm_NusG_bac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01014">
        <property type="entry name" value="NUSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="8">
        <location>
            <begin position="28"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="9">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="204" mass="23335" checksum="16576F9CBCC50160" modified="2004-07-05" version="1">MNKTEKQIKETQAQEQQDQEKDSQNTCHLKWYIAQTYSGYENVVKDDLLRRVESIGIGDLVSNVLSPKEEYYETRLDGKKVKKERKMYPGYVFIQMMITDRSWFVVRNTPRITGFLGSSGMGSKPVPLSENEINPVLLKMGIINKPDYKNFIGKKVEIISGSFSGQIGQVSSIDDDREKMTVEVDLFGRATPVEISFNDFKEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="127" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQY3</accession>
    <name>Q6YQY3_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">der</name>
        <name evidence="11" type="ordered locus">PAM_240</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_240"/>
    <dbReference type="EnsemblBacteria" id="BAD04325">
        <property type="protein sequence ID" value="BAD04325"/>
        <property type="gene ID" value="PAM_240"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_240"/>
    <dbReference type="eggNOG" id="COG1160">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016077_6_2_14"/>
    <dbReference type="OMA" id="KFRFLEY"/>
    <dbReference type="OrthoDB" id="263682at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-288-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTP-bd_EngA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="3"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="215"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="56"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="118"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="221"/>
            <end position="228"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="268"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="333"/>
            <end position="336"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAD04325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="478" mass="54332" checksum="EB0DF48921C63E25" modified="2004-07-05" version="1">MSFKIAIVGRPNVGKSSLFNRIIGRRHAITHQKAGITRDRIYATAEWFTKTFGVIDTGGIEIQSTPFLEQIKLQAQLAVDEADVIVFVVDGQTGLTQNDIYLAKLLYKTKKPVLLAVNKIDNHNLLSNTYEFYALGFDTPFAISTQHGIGIGDLLDKIVFLMRDAALISDSSFLEDLSIDTPLQSPPSEFNYEIPEKQLLEPEQNQNQEKDNNIIKFCVVGRPNVGKSTLTNSLLASQRMIVSDMAGTTTDAVDTFFENDGQKYQIIDTAGIKKRGKIYEQEDKYSVLRALGALEKADIACLVLDAKEGILEQDKNIAGFILEHHKACIIIVNKWDLLEKDTNTLKNFEQKIRQEFVFLSYAPVIFLSALKKSRLTQIFAILKRVFNNYKSQFSTSLLNDILQEATLITPPTFFNQKKAKFQYIFQTKTKAPEFLCFVNDPKHIHFSYERFLKNQFRKSLDLEGTPLKIIFHQKKSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="127" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQZ0</accession>
    <name>Q6YQZ0_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="6">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">metG</name>
        <name evidence="11" type="ordered locus">PAM_233</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="6"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_233"/>
    <dbReference type="EnsemblBacteria" id="BAD04318">
        <property type="protein sequence ID" value="BAD04318"/>
        <property type="gene ID" value="PAM_233"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_233"/>
    <dbReference type="eggNOG" id="COG0143">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009710_9_4_14"/>
    <dbReference type="OMA" id="SDMHGTP"/>
    <dbReference type="OrthoDB" id="761140at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-279-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01228">
        <property type="entry name" value="Met_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="PTHR43326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="8">
        <location>
            <begin position="4"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1g" evidence="9">
        <location>
            <begin position="142"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_3" evidence="10">
        <location>
            <begin position="404"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="6">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="6">
        <location>
            <begin position="302"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAD04318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="520" mass="60083" checksum="06760C0ACEEA47F8" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="114" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR00</accession>
    <name>Q6YR00_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">map</name>
        <name evidence="5" type="ordered locus">PAM_222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_222"/>
    <dbReference type="EnsemblBacteria" id="BAD04307">
        <property type="protein sequence ID" value="BAD04307"/>
        <property type="gene ID" value="PAM_222"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_222"/>
    <dbReference type="eggNOG" id="COG0024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015857_0_1_14"/>
    <dbReference type="OMA" id="GDHAYTF"/>
    <dbReference type="OrthoDB" id="1285136at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-268-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="12"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="247" mass="27247" checksum="DB7768E9F28EA927" modified="2004-07-05" version="1">MISIKTPHEIAIMKQAGKIINEAHRLLASFVIPGMSTFDLDLLAKNFYQKKSVISAFKGYNGFPKHICASVNEVVVHGIPSKKTILKQGDIITLDLGINYQGYYVDCAYSYVVGTFCQTTQNLLALTQKALFQGLLQIKPQNHFSDISHAIELFAKNNNLGIVEEFTGHGIGTSLHEEPYIPNFGKPHEGAILQPGMTFCVEPMLTLGNPEIAILQDNWTVVTTDKSLSAHFEHTVLVTPTGYEILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR02</accession>
    <name>Q6YR02_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">secY</name>
        <name evidence="13" type="ordered locus">PAM_220</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 12">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_220"/>
    <dbReference type="EnsemblBacteria" id="BAD04305">
        <property type="protein sequence ID" value="BAD04305"/>
        <property type="gene ID" value="PAM_220"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_220"/>
    <dbReference type="eggNOG" id="COG0201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030313_0_1_14"/>
    <dbReference type="OMA" id="FAMWLGE"/>
    <dbReference type="OrthoDB" id="1567535at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-266-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAD04305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="413" mass="45908" checksum="E42C1D790AACE1C7" modified="2004-07-05" version="1">MKRQLKLVLGNRKLMFQIFFTLFIISIVCLGTSWPLPFINTKSLDLSKLFGVFSINAGTLFGLGITPYITASIVVQFLQKLLPICREWKDQGQMGKRKLNLLTRSLALLFAFGQSFAFLNSYSKLFVTSISTSQLFLLALIATAGVAVLIWFADLINSKGIGNGTSILIVVSMSHSLINLFVNLKESYLSQNNFLTLKTFNFACIVLLLLLFLIFTVVVQITSLKIPINYARNQVQGKSYIPLKINSAGVMPVILASALLQPFQMLAGVIGNTKFTEVVDFFAKTNFPENQINFFAIGFLVLLVIVFSFFSAFMNVNPEDISEHLSKQDAYIAGLRPGEQTTRYLANTLFKITVLGTVFIAALVVTPILMEHFLGLKDMKLGGTSLLIIVSVALETIQRIKATANKKEYQKLF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-08-16" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR20</accession>
    <name>RL32_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmF</name>
        <name type="ordered locus">PAM_198</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR20"/>
    <dbReference type="SMR" id="Q6YR20"/>
    <dbReference type="STRING" id="262768.PAM_198"/>
    <dbReference type="EnsemblBacteria" id="BAD04283">
        <property type="protein sequence ID" value="BAD04283"/>
        <property type="gene ID" value="PAM_198"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_198"/>
    <dbReference type="eggNOG" id="COG0333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129084_2_3_14"/>
    <dbReference type="OMA" id="THYKLSN"/>
    <dbReference type="OrthoDB" id="2092354at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-242-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000172379" description="50S ribosomal protein L32">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <sequence length="68" mass="7824" checksum="95347D1282BBB80A" modified="2004-07-05" version="1">MAVPFRRTGKTAKRKRRTHYKLSNPALVLCKETNTFTLSHRVTKNSGYYKGKLILENKPSKAQKTTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR27</accession>
    <name>Q6YR27_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type dipeptide/oligopeptide transport system, periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">oppA</name>
        <name evidence="3" type="ordered locus">PAM_191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_191"/>
    <dbReference type="EnsemblBacteria" id="BAD04276">
        <property type="protein sequence ID" value="BAD04276"/>
        <property type="gene ID" value="PAM_191"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_191"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_520575_0_0_14"/>
    <dbReference type="OMA" id="TYYGRFV"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-235-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="89"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="523" mass="59986" checksum="18EE1D6938F2F0EB" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-12-20" modified="2022-08-03" version="110" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR34</accession>
    <name>SYI_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Isoleucyl-tRNA synthetase</fullName>
            <shortName evidence="1">IleRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ileS</name>
        <name type="ordered locus">PAM_184</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR34"/>
    <dbReference type="SMR" id="Q6YR34"/>
    <dbReference type="STRING" id="262768.PAM_184"/>
    <dbReference type="PRIDE" id="Q6YR34"/>
    <dbReference type="EnsemblBacteria" id="BAD04269">
        <property type="protein sequence ID" value="BAD04269"/>
        <property type="gene ID" value="PAM_184"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_184"/>
    <dbReference type="eggNOG" id="COG0060">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_7_1_14"/>
    <dbReference type="OMA" id="HLGTAWN"/>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-225-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02002">
        <property type="entry name" value="Ile_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023585">
        <property type="entry name" value="Ile-tRNA-ligase_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000098433" description="Isoleucine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region">
        <location>
            <begin position="591"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="550"/>
        </location>
        <ligand>
            <name>L-isoleucyl-5'-AMP</name>
            <dbReference type="ChEBI" id="CHEBI:178002"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="594"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="876"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="879"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="892"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="895"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02002"/>
        </source>
    </evidence>
    <sequence length="900" mass="104373" checksum="023BA5BF424BF031" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR35</accession>
    <name>Q6YR35_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ychF</name>
        <name evidence="7" type="ordered locus">PAM_183</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_183"/>
    <dbReference type="EnsemblBacteria" id="BAD04268">
        <property type="protein sequence ID" value="BAD04268"/>
        <property type="gene ID" value="PAM_183"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_183"/>
    <dbReference type="eggNOG" id="COG0012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018395_0_1_14"/>
    <dbReference type="OMA" id="VLRCFDN"/>
    <dbReference type="OrthoDB" id="603226at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-224-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="5">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="6">
        <location>
            <begin position="278"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="363" mass="40819" checksum="D375A7247CC2C7A6" modified="2004-07-05" version="1">MKVGIIGLPNVGKSTLFNALTKMQVLEANYPFATIEPNVGIVEVSDSRLQTLSQIFQSQKTISALIEFKDIAGLVAGASKGEGLGNQFLSHIRNVDAICHVVKCFEDPNIAHVTETNNPVEEIDIIQTELALADLEQIEKRLLKLGKQKNKLDKELLQEKALLTKIKTHLTTQDLKNLVFSDEELKLVKTFNLLFLKPSLYLANIKEHDLLSLDSNVFYQQVLAYATKESKKLIPLCVQLEKEISSLDFAEKQLFLKDYGLVESGLTKLIQESYALLGLQTYFTAGPKEVRAWSFKKGLKAPECARIIHTDLQKGFIKAEVVSYLDLLEAQTFQKSKEKGKVRIEGKEYIVKDGDIITFRFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="120" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR62</accession>
    <name>Q6YR62_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">priA</name>
        <name evidence="12" type="ordered locus">PAM_154</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_154"/>
    <dbReference type="EnsemblBacteria" id="BAD04239">
        <property type="protein sequence ID" value="BAD04239"/>
        <property type="gene ID" value="PAM_154"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_154"/>
    <dbReference type="eggNOG" id="COG1198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013353_4_1_14"/>
    <dbReference type="OMA" id="MISKGHD"/>
    <dbReference type="OrthoDB" id="1132322at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-187-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="304"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="552"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="533"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="560"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAD04239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="819" mass="95076" checksum="791E399D4B9C8D86" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR75</accession>
    <name>SYC_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="1">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cysS</name>
        <name type="ordered locus">PAM_141</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR75"/>
    <dbReference type="SMR" id="Q6YR75"/>
    <dbReference type="STRING" id="262768.PAM_141"/>
    <dbReference type="EnsemblBacteria" id="BAD04226">
        <property type="protein sequence ID" value="BAD04226"/>
        <property type="gene ID" value="PAM_141"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_141"/>
    <dbReference type="eggNOG" id="COG0215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013528_0_0_14"/>
    <dbReference type="OMA" id="AKYWMHN"/>
    <dbReference type="OrthoDB" id="952207at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-173-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000159449" description="Cysteine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region">
        <location>
            <begin position="264"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <sequence length="438" mass="51684" checksum="07E89A6A115DA1D9" modified="2004-07-05" version="1">MLKIYNSLTRKKEFFNPAHPPQINMYVCGPTVYNHLHLGNTRPLIFFDTVKRYLEMLNFRVYYVVNITDIDDKIIENALKNQVLEQDLANKYIKSFNNLLKTLNIQTINFKPQATQYINSMIVYIQTLLDQGFAYFTDQGIYFRVSKIDDYGKLKKQDLSQLKQNARKQLDPQKEFPGDFILWKKTSQGITYPSPWFAGRPGWHTECATMIEQLFKLPLDIHGGGTDLKFPHHENEIAQTHAHSHQKLANFFMHVERLDYQNQKMSKSLGNIIWCKDLLKQYNPCIIKLLILSTHYRKPINFSYDLMEQAQQKYQKITDFLTKNNFYLKVNQFSCQALDQDIMQLFHQLMQDDLATHKVIDLMEQTIKQAHQTQILDKLSQFQNSLLLILNILGITIPFNKPTKTDLQTYFLWQDARKYRDFAQADILRKQLLDKGFI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-29" modified="2022-08-03" version="116" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR88</accession>
    <name>SYD_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartate--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="1">AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aspS</name>
        <name type="ordered locus">PAM_128</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR88"/>
    <dbReference type="SMR" id="Q6YR88"/>
    <dbReference type="STRING" id="262768.PAM_128"/>
    <dbReference type="PRIDE" id="Q6YR88"/>
    <dbReference type="EnsemblBacteria" id="BAD04213">
        <property type="protein sequence ID" value="BAD04213"/>
        <property type="gene ID" value="PAM_128"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_128"/>
    <dbReference type="eggNOG" id="COG0173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014330_3_2_14"/>
    <dbReference type="OMA" id="YQLDVEM"/>
    <dbReference type="OrthoDB" id="226836at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-160-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000110914" description="Aspartate--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="1">
        <location>
            <begin position="197"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="219"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="532"/>
            <end position="535"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <sequence length="586" mass="67521" checksum="7CC2D6920BA74B49" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="121" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR95</accession>
    <name>Q6YR95_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">groES</name>
        <name evidence="4" type="ordered locus">PAM_120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_120"/>
    <dbReference type="EnsemblBacteria" id="BAD04205">
        <property type="protein sequence ID" value="BAD04205"/>
        <property type="gene ID" value="PAM_120"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_120"/>
    <dbReference type="eggNOG" id="COG0234">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132825_2_3_14"/>
    <dbReference type="OMA" id="HVIYGGY"/>
    <dbReference type="OrthoDB" id="1965002at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-152-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="89" mass="9660" checksum="68D73689503D9BB4" modified="2004-07-05" version="1">MKQKTIIPLHDNVVLKLKMEETKTASGIILALSEKEKSSVGVVVGVGSKVEGLKKDDEVVYKSYSGSKVTLGEKDYLIVAVKDILAQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRA1</accession>
    <name>Q6YRA1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_114"/>
    <dbReference type="EnsemblBacteria" id="BAD04199">
        <property type="protein sequence ID" value="BAD04199"/>
        <property type="gene ID" value="PAM_114"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_114"/>
    <dbReference type="HOGENOM" id="CLU_2274500_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="102" mass="11359" checksum="E6D3C6A666EF25FE" modified="2004-07-05" version="1">MDPFNSFNFVLIYFILSFLLVPVKGGNSVVVFFFNAAKLSLVLGVLLGSDNVMLFNAFSNSCSFFSKSSNIFFSCCVKFRYVGLVVLNSSNLWFCSGEKKFA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-01" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRB1</accession>
    <name>KITH_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thymidine kinase</fullName>
            <ecNumber evidence="1">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tdk</name>
        <name type="ordered locus">PAM_104</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRB1"/>
    <dbReference type="SMR" id="Q6YRB1"/>
    <dbReference type="STRING" id="262768.PAM_104"/>
    <dbReference type="PRIDE" id="Q6YRB1"/>
    <dbReference type="EnsemblBacteria" id="BAD04189">
        <property type="protein sequence ID" value="BAD04189"/>
        <property type="gene ID" value="PAM_104"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_104"/>
    <dbReference type="eggNOG" id="COG1435">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064400_3_0_14"/>
    <dbReference type="OMA" id="ENTVNHK"/>
    <dbReference type="OrthoDB" id="1279539at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-135-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00124">
        <property type="entry name" value="Thymidine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0237">DNA synthesis</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000175001" description="Thymidine kinase">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="16"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="90"/>
            <end position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00124"/>
        </source>
    </evidence>
    <sequence length="209" mass="23351" checksum="4C432E38F5AB8AA7" modified="2004-07-05" version="1">MTQKEQGQGFIEVVCGPMFAGKTEALIQRSNQALQLNKKILSFKPQIDDRYSVKEEIVSHNQNTIPAILIDKSKDILPFITPEINVVIIDEAQFLDNDIVAIVDYLANCNIEVIISGLELDFCGKPFGPMPYLLAIADTVTKLTSICAISGKKANRTQRLIDGKPAQSNEPVVLVGGKEYHEPRCRKHHCLADIDKTKINWQNFTNQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRB2</accession>
    <name>Q6YRB2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytosine/adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">PAM_103</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_103"/>
    <dbReference type="EnsemblBacteria" id="BAD04188">
        <property type="protein sequence ID" value="BAD04188"/>
        <property type="gene ID" value="PAM_103"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_103"/>
    <dbReference type="eggNOG" id="COG0590">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025810_3_2_14"/>
    <dbReference type="OMA" id="PCQMCAG"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-134-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008251">
        <property type="term" value="F:tRNA-specific adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14437">
        <property type="entry name" value="MafB19-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="161" mass="18474" checksum="B48DB8E4EDFCD30D" modified="2004-07-05" version="1">MENNNQQHIFFMKEALKEAQKAYLKEEVPIGAVAVLNQKIIARAHNNRNTKKLFFGHAEFLALMKAGKKINSRFLNDVSLYVTLEPCLMCTGAIIQAGIKNLYYGTSMEKSYSFNDMSSIQNMPFMDKLNIQSGLLAQESMQLLQKFFQELRIKKNNLLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-08-12" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRB6</accession>
    <name>Q6YRB6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_099"/>
    <dbReference type="EnsemblBacteria" id="BAD04184">
        <property type="protein sequence ID" value="BAD04184"/>
        <property type="gene ID" value="PAM_099"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_099"/>
    <dbReference type="eggNOG" id="COG1464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2082425_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="117" mass="13352" checksum="A2C3AD1C8EC1A894" modified="2004-07-05" version="1">MILLKKIGIVEVREQTIQEKGFNLSLKDVKNIYDFEFIKTSHLLEIPQKFQDTQKYDLTINCPGMMRDSNFVRVGSIGLGKEENIEPQEDVFLSYAVILAAKTGTETPPKVTIINKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="112" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRC2</accession>
    <name>Q6YRC2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type Mn/Zn transport system, ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">znuC</name>
        <name evidence="5" type="ordered locus">PAM_093</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="Q6YRC2"/>
    <dbReference type="STRING" id="262768.PAM_093"/>
    <dbReference type="EnsemblBacteria" id="BAD04178">
        <property type="protein sequence ID" value="BAD04178"/>
        <property type="gene ID" value="PAM_093"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_093"/>
    <dbReference type="eggNOG" id="COG1121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_14"/>
    <dbReference type="OMA" id="SVWDVVM"/>
    <dbReference type="OrthoDB" id="1721927at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-124-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="254" mass="29134" checksum="DE5C19A5F6CD5D11" modified="2004-07-05" version="1">MKKEIAIKIRDLTVAYHLKPVLWDIDLNIYQSSLTAILGPNGAGKSTLIKTILELIPKVSGEVLFYNQKYGQVRKKISYVPQRNSVDWDFPTTVFDVVLMGRYGHLGWFKKPTAKDKEIVMQSLEKTGMQDLKDRQISELSGGQQQRIFLARALAQQGDIYFMDEPFQGVDIQTEKKIIQVLKDLQKENKTIIVVHHDLETVTQYFDHVVLVNVQKIASGTTDEVFNQTNLTKTFQNKQLKKDIHNLQTPKTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRC5</accession>
    <name>Q6YRC5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized phage-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gepA</name>
        <name evidence="1" type="ordered locus">PAM_090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04175">
        <property type="protein sequence ID" value="BAD04175"/>
        <property type="gene ID" value="PAM_090"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_090"/>
    <dbReference type="eggNOG" id="COG3600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2826909_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-120-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="66" mass="8002" checksum="5578F8CB65B175B8" modified="2004-07-05" version="1">MNFVTRNTRIYISDYANYIIKKIDVNHMKLQKLLYYSYAAYLFKYKESLSVNLVEAWQKGPVFKRL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-06-07" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRC7</accession>
    <name>RL27_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmA</name>
        <name type="ordered locus">PAM_088</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRC7"/>
    <dbReference type="SMR" id="Q6YRC7"/>
    <dbReference type="STRING" id="262768.PAM_088"/>
    <dbReference type="EnsemblBacteria" id="BAD04173">
        <property type="protein sequence ID" value="BAD04173"/>
        <property type="gene ID" value="PAM_088"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_088"/>
    <dbReference type="eggNOG" id="COG0211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095424_4_0_14"/>
    <dbReference type="OMA" id="GKDHTLH"/>
    <dbReference type="OrthoDB" id="1904463at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-117-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000181137" description="50S ribosomal protein L27">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <sequence length="92" mass="10103" checksum="BD1BDF345A99A3E7" modified="2004-07-05" version="1">MLLQLQIQLFASKKGAGSTRNGRDSHSKRLGAKLSDGQFAKAGAIIYRQRGTKIHPGFNVGRGGDDTLFAKMSGIIKFEKKHGRKKVSVYLQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-15" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRD4</accession>
    <name>RS20_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsT</name>
        <name type="ordered locus">PAM_081</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds directly to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS20 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRD4"/>
    <dbReference type="SMR" id="Q6YRD4"/>
    <dbReference type="STRING" id="262768.PAM_081"/>
    <dbReference type="EnsemblBacteria" id="BAD04166">
        <property type="protein sequence ID" value="BAD04166"/>
        <property type="gene ID" value="PAM_081"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_081"/>
    <dbReference type="eggNOG" id="COG0268">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_160655_0_1_14"/>
    <dbReference type="OMA" id="GVIHKNA"/>
    <dbReference type="OrthoDB" id="2005443at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-109-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00500">
        <property type="entry name" value="Ribosomal_S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002583">
        <property type="entry name" value="Ribosomal_S20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036510">
        <property type="entry name" value="Ribosomal_S20_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33398">
        <property type="entry name" value="PTHR33398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01649">
        <property type="entry name" value="Ribosomal_S20p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46992">
        <property type="entry name" value="SSF46992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00029">
        <property type="entry name" value="S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000168003" description="30S ribosomal protein S20">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="86" mass="9777" checksum="453ED10AD40364BD" modified="2004-07-05" version="1">MANIKQQKKRNKTNEKRRLQNVSFKSSVKTVVKQVKTAVANADKQKALALLSVAYKKFDKGVSKRVYHANFSARNKSDLQKLVNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRD7</accession>
    <name>Q6YRD7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC-type amino acid transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">artM</name>
        <name evidence="9" type="ordered locus">PAM_078</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_078"/>
    <dbReference type="EnsemblBacteria" id="BAD04163">
        <property type="protein sequence ID" value="BAD04163"/>
        <property type="gene ID" value="PAM_078"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_078"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_20_3_14"/>
    <dbReference type="OMA" id="QIFMIYF"/>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-106-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018313">
        <property type="entry name" value="SBP_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01039">
        <property type="entry name" value="SBP_BACTERIAL_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="569"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="389"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAD04163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="601" mass="68155" checksum="A6CB4507DCC457D5" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRE4</accession>
    <name>Q6YRE4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YqaJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_071"/>
    <dbReference type="EnsemblBacteria" id="BAD04156">
        <property type="protein sequence ID" value="BAD04156"/>
        <property type="gene ID" value="PAM_071"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_071"/>
    <dbReference type="eggNOG" id="COG5377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1209247_0_0_14"/>
    <dbReference type="OrthoDB" id="1563636at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-95-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017482">
        <property type="entry name" value="Phage_endonuclease_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019080">
        <property type="entry name" value="YqaJ_viral_recombinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09588">
        <property type="entry name" value="YqaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03033">
        <property type="entry name" value="phage_rel_nuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YqaJ" evidence="1">
        <location>
            <begin position="13"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="215" mass="25464" checksum="92FA7BE23AEA11CB" modified="2004-07-05" version="1">MRIKNLNQRTQLWYQHRKKYINASEIASITGLDPFRSMEQLVHDKLFGTTFTANQYTLHGQKMEPIAREFFIQKTNLTFEDAIFTDDQVHLFSASLDGYNEQHQAVLEIKCPFVNVNQAVSTTWTDFLTNPQLENIPKYYWAQVQCQLYCAQAKSAYFLVYFNDQNYHVFRIYQDKNFISKMIADSKKYLNLLNKAKEELSQTTYLKQLSEIKYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRE6</accession>
    <name>Q6YRE6_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SVM_signal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_069"/>
    <dbReference type="EnsemblBacteria" id="BAD04154">
        <property type="protein sequence ID" value="BAD04154"/>
        <property type="gene ID" value="PAM_069"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_069"/>
    <dbReference type="HOGENOM" id="CLU_1188980_0_0_14"/>
    <dbReference type="OrthoDB" id="2111648at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-91-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021970">
        <property type="entry name" value="SVM_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12113">
        <property type="entry name" value="SVM_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SVM_signal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="233" mass="27754" checksum="BE2C957A0B4660AF" modified="2004-07-05" version="1">MFKLQNQFKIISFCLFVLLGILFITNNYYVMAMKNNELQNNSNFNDNNIEIPFENLPKQQTIQINNSFHEKNIIKFLFETKINLSKKLGVYDLKNLKEKYNGFLIKFNINVKQFFNTNNAKICLYSNASDLDNPIYDRYNFIGFLERIIIDNVSEEGLFNYKLKNNNHIEIYKSVFKQGLDNNLSESELEENVFKIILDFDIKKESNDLYMFFILYSYGFTESKNYEYGQENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRE9</accession>
    <name>Q6YRE9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_066"/>
    <dbReference type="EnsemblBacteria" id="BAD04151">
        <property type="protein sequence ID" value="BAD04151"/>
        <property type="gene ID" value="PAM_066"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_066"/>
    <dbReference type="HOGENOM" id="CLU_959212_0_0_14"/>
    <dbReference type="OrthoDB" id="2121724at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-87-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="286" mass="32501" checksum="915E41D2660479FF" modified="2004-07-05" version="1">MSKKTNKNSKNQSKNNKSNEIIIKRKNPTPKIIIETQTKKENWLFKIIKTFFNIFKWFIPLLLIGGAFYWTLFKFFPEVLNQINAFTSNAVTKTKILYDKATQPIRTFVEYIYNKLTGNDKDPNHVPSPQNKLGYYLATTLSVIGICLGIGKIGNWLKSRKKKTIKKGTTKAIKKTAPSKLANLGGKALRIGSKALFLVSLASTAYELYQFYREENKTPNPPQQLTNKIENPSTPISQTPSIQQSFNPTIIENEESNITNNNEDKTETTQEEITQEESESGNLNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRF5</accession>
    <name>Q6YRF5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04145">
        <property type="protein sequence ID" value="BAD04145"/>
        <property type="gene ID" value="PAM_060"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_060"/>
    <dbReference type="HOGENOM" id="CLU_1179266_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="235" mass="27471" checksum="7EEAAF6833EBA741" modified="2004-07-05" version="1">MINKRILRNRKIILNCTNNLLKQEILRINNSDYPGLNQAQKITNEKNQITHIIFPDGAIEEFNPENKMLIQTVYPKEGIIILNSLFTIKADKEYNPSTNIPNCQKNISLLSFEDTNFSSNSQDITKYVESKLKKQEITETFSNGKPNKIITTYYYSGNECKNEYDENEKLISTTMKFDPDRIIKYLDNEVDQVKIEIIYKQSEKNDKPTETYPYEGKCQYCTQILKPDDKILLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRG2</accession>
    <name>Q6YRG2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_053</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04138">
        <property type="protein sequence ID" value="BAD04138"/>
        <property type="gene ID" value="PAM_053"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_053"/>
    <dbReference type="HOGENOM" id="CLU_114409_0_0_14"/>
    <dbReference type="OMA" id="YCFFHAL"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-69-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="164" mass="19305" checksum="2704009E8AED268B" modified="2004-07-05" version="1">MQLTCKLAYLGLNQFVNGLENDQFKEQYLLIFNGDSSFFENDVLSYSLRTASTPLIQGTLDFLGKQLKRKFNLIINDKHLLSSFLFDNNPIDLKMKNNNYHFFIQKPEDTKGDGYCFFHALIFLLKEKKLFSENIINASFDKIDLIKNSYNILYKIKKIKEKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRG8</accession>
    <name>Q6YRG8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_047"/>
    <dbReference type="EnsemblBacteria" id="BAD04132">
        <property type="protein sequence ID" value="BAD04132"/>
        <property type="gene ID" value="PAM_047"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_047"/>
    <dbReference type="eggNOG" id="COG4942">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_705647_0_0_14"/>
    <dbReference type="OMA" id="VQTELNM"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-63-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="391" mass="46401" checksum="756F4164E48E4601" modified="2004-07-05" version="1">MKLKKKQPKKKVKLVTLTIPDHGSVESTIEPTLLQQEQLQQTPLLGEELKETNQTTETQQLTPEEIIKAKNLLEIQLQQEKMNSLTLETQKANLEYDLTQKQEELKNNQKLSQQEKQELQKEINQQTDKIRSKEDEIFTQDQKINQLETDLHQEKTLNTEKEKQINELINQINEQNQMTKQLQNQLQEQKSLIEMKNQELITNQALSEQEKQELQKEINQLTTNFQQKQKEYENTINQKDQEIDQLNQIIHEQANKINRLSEELEQQIDKWVQQGLHIEALEGTIKALEKFSGKYLEENVELRHEINKLKEQIKDEQKAHEETKVELKEKCDKLIEKTTEYDQIKKIIDNQKTWKGSIQPFTTKIKDDVNRNVASVKEKVNKVTSWFKKWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="118" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRH4</accession>
    <name>Q6YRH4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_041</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_041"/>
    <dbReference type="EnsemblBacteria" id="BAD04126">
        <property type="protein sequence ID" value="BAD04126"/>
        <property type="gene ID" value="PAM_041"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_041"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-57-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="109" mass="12681" checksum="A901A1B77051E42D" modified="2004-07-05" version="1">MLNKVQLIGRLSHDLEKQYINSNNEQIPKIDFQLAVNNKEITQFIPCVAFRKQAENMKKHLHKGSKIYLEGILSIQKYTNNEGQTKINTKVILQNVIFLDNKPQETLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRH8</accession>
    <name>Q6YRH8_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chromosome segregation ATPase homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">smc</name>
        <name evidence="1" type="ordered locus">PAM_037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_037"/>
    <dbReference type="EnsemblBacteria" id="BAD04122">
        <property type="protein sequence ID" value="BAD04122"/>
        <property type="gene ID" value="PAM_037"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_037"/>
    <dbReference type="HOGENOM" id="CLU_942813_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="295" mass="35119" checksum="60B84C7C45BD294A" modified="2004-07-05" version="1">MSNENQDATTTNEPLQLSLLEQEIKSLRNKLSGLLQEKINKYLATKSKNKSQLEQYLKIVKNVLNKRLQEIQTQYTSDLEPPQVIPLRSEIEMINLLTQGIDEAQSEILFEYDRVLIPLEQQYQEINKFIEQLNLEQDTSTLESFKSEFDVFLKNCLNQNKQFYKDIEDKQKDLKEIDLKNYQDTETKIQVLLSQAEQNQTKYSNIFDEVQLNHIDQNNNKIVVINDNITKDELILDYMEENTYISRQDFLKESHNAYVNRIFLEAFMSCCKNLMKPIYYHKWFLDHKQDLTYQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRI6</accession>
    <name>Q6YRI6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_029</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04114">
        <property type="protein sequence ID" value="BAD04114"/>
        <property type="gene ID" value="PAM_029"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_029"/>
    <dbReference type="HOGENOM" id="CLU_1729537_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-38-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="151" mass="17438" checksum="B8DCE6BEF0C7E584" modified="2004-07-05" version="1">MQQPQKDNKNFIVLTIAFTVLMLGLILGVCWVLKSKQEPTKEETFKLPTETYKPDYSNNEGTYTGSQVNQNPYLPSQTFTTTSQPQTTNSQPTQTQTPQGKLIKKQEYKSNGTKSDYCTYEYNSKGQPTKKQNYDFDGTKDNYITYEYNYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRI7</accession>
    <name>Q6YRI7_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_027"/>
    <dbReference type="EnsemblBacteria" id="BAD04112">
        <property type="protein sequence ID" value="BAD04112"/>
        <property type="gene ID" value="PAM_027"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_027"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_294035_0_0_14"/>
    <dbReference type="OMA" id="HIFQSHL"/>
    <dbReference type="OrthoDB" id="39791at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-36-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="994"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="1032" mass="120818" checksum="B21719A3E9C4B56C" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-12-02" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRJ0</accession>
    <name>Q6YRJ0_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_024"/>
    <dbReference type="EnsemblBacteria" id="BAD04109">
        <property type="protein sequence ID" value="BAD04109"/>
        <property type="gene ID" value="PAM_024"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_024"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031786_1_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010964">
        <property type="entry name" value="M20A_pepV-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01887">
        <property type="entry name" value="dipeptidaselike"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="263" mass="29734" checksum="06598B6DA3526816" modified="2004-07-05" version="1">MLDLGHQSGFKTLNLEGYAGHMEYGEQKEWVGMIGHSDVVPTGTGWTYPPYEALIVDDKIYGRVSQDNKGPVIASYFALKILKELNLPLSKRIKFILGVDEETGFRCMKHYFTKLPEMPVSGFVPDSHFPAVYCEKGFAFFNFEGEVSDNKIVSIQSGQASNVVPNLAEALLVYDPVYKTLFDEYMQKSDMKASLKKYSNLWKLTVYGKSTHGSTPEKGKNALYDLMKMLKVLGIKNNLVNFYDKYLVDSLDGKKLGIDHYDE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-11-28" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRJ5</accession>
    <name>Y019_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0397 protein PAM_019</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">PAM_019</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0397 family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAD04104" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04104.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YRJ5"/>
    <dbReference type="STRING" id="262768.PAM_019"/>
    <dbReference type="EnsemblBacteria" id="BAD04104">
        <property type="protein sequence ID" value="BAD04104"/>
        <property type="gene ID" value="PAM_019"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_019"/>
    <dbReference type="eggNOG" id="COG4720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120023_0_0_14"/>
    <dbReference type="OMA" id="WWSWVIA"/>
    <dbReference type="OrthoDB" id="1637464at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-24-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01572">
        <property type="entry name" value="UPF0397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009825">
        <property type="entry name" value="ECF_substrate-spec-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022914">
        <property type="entry name" value="UPF0397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07155">
        <property type="entry name" value="ECF-ribofla_trS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000260799" description="UPF0397 protein PAM_019">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="185" mass="20704" checksum="8A80EC15C7EC3599" modified="2006-11-28" version="2">MSKDDSIKKTVTIGLSAAIFFVLSCFASIPVGFNVSIETSVAFLAFIAVAFGPAVGFYVGLIGNTIKDFILFGNVSWNWVLCSALIGFIYGLPHKIIDLKYQVFTKKKIVYFWLYQVAFNFIIWGFFAPQSDLLIYGQPPKLVYLQSFLIVISNILAYSVVGIKLMSMYSCHYNKQATLIKINNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRK6</accession>
    <name>Q6YRK6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1,2-diacylglycerol 3-glucosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rfaG</name>
        <name evidence="3" type="ordered locus">PAM_008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_008"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04093">
        <property type="protein sequence ID" value="BAD04093"/>
        <property type="gene ID" value="PAM_008"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_008"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_2_0_14"/>
    <dbReference type="OMA" id="FFCPNAG"/>
    <dbReference type="OrthoDB" id="948440at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-12-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="212"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="415" mass="48068" checksum="D6584EB207C2BDED" modified="2004-07-05" version="1">MKIGIFTDSYKPLISGVVVSCDSLREGLEALGHEVYIITTNCPKVKQEKDSRVIRIKGMPLPFKIFKDYRWVLSYKKHLFKIKALNLDVIHVHTEFGVGSLGLLAKQKLNLPLVYTTHTMYVAFFDTQKSFIVKCFKKPILKYVDYLFTKFIFNSDVNILPTKKVLYFLENRYSNKVNDTSKINYQIVPTGFNLEKFYCHNHSPEKVFSLKQQLGLKDSFVCLYVGRISAEKEIDYLMDAFTSFHLQNPKSKFLIIGDGPERKNLEKKAKKLNLDDKIIFLGFVAYDKLGIYYQLGNVFINASLFETQGLTYIEALAASLPCVVRFDQALEGVIKHEQNGFFYHNQEQLITILTSLYQNPDNFKQLSYQAQKSVNLYTQKTFVTNVLEVYNQAIDNHKLKKQKLIQHQKETSDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-02-05" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A9JQS8</accession>
    <name>A9JQS8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ordered locus">PAM_759</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAF95569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_759"/>
    <dbReference type="EnsemblBacteria" id="BAF95569">
        <property type="protein sequence ID" value="BAF95569"/>
        <property type="gene ID" value="PAM_759"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_759"/>
    <dbReference type="eggNOG" id="COG0629">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078758_6_1_14"/>
    <dbReference type="OMA" id="FVIERFW"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-509-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF95569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="104" mass="11908" checksum="D4AEE549E3626240" modified="2008-02-05" version="1">MLNKVQLIGNIAHNLEKQYINSNNEQIPKIDFNLAINNKDKVQYIPCVVFRNQAENMSTYLNKGSKIYAEGALSIQKYTTNEGKTRTTTKVIIQNVIFLDNKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-06-28" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>B9A0T2</accession>
    <name>B9A0T2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <organism evidence="2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2">
        <name>EcOYM</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2002" name="Microbiology" volume="148" first="1389" last="1396">
            <title>Evidence of intermolecular recombination between extrachromosomal DNAs in phytoplasma: a trigger for the biological diversity of phytoplasma?</title>
            <authorList>
                <person name="Nishigawa H."/>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Jung H.Y."/>
                <person name="Kuboyama T."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="11988512"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
            <plasmid evidence="2">EcOYM</plasmid>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
            <plasmid evidence="2">EcOYM</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB076263">
        <property type="protein sequence ID" value="BAH22132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959586.1">
        <property type="nucleotide sequence ID" value="NC_019167.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959592.1">
        <property type="nucleotide sequence ID" value="NC_019168.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_006959598.1">
        <property type="nucleotide sequence ID" value="NC_019169.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_214980.1">
        <property type="nucleotide sequence ID" value="NC_006903.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Plasmid EcOYM"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAH22132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="135" mass="16057" checksum="55E10AF2BC311444" modified="2011-06-28" version="1">MKSIFNKFKFINKKIFFCLILFSLSYILTNSKYNTFACNVSNSNKEQKQEISVKEEYRKEDFDIFKVKVLNPADKIRNDFLQIAIINWILDDSTTLEEIKKDISNRLIGEESIFVPLDMYRNSLAQNFFTYPPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPI1</accession>
    <name>Q6YPI1_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DHH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_746"/>
    <dbReference type="EnsemblBacteria" id="BAD04831">
        <property type="protein sequence ID" value="BAD04831"/>
        <property type="gene ID" value="PAM_746"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_746"/>
    <dbReference type="eggNOG" id="COG0618">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039720_1_0_14"/>
    <dbReference type="OMA" id="IWINHIC"/>
    <dbReference type="OrthoDB" id="1040743at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-901-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="1">
        <location>
            <begin position="13"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="312" mass="35740" checksum="7B78279106717583" modified="2004-07-05" version="1">MKFIETQIKTFDTIIIHGHKNPDGDCYGSQLGLKNMIQNTFPHKNVYVVGQTKNHLTFLGQMDEIPDETYQNALVIVVDCGTTQAISDQRFKLGKVVIRIDHHILIENYGNYQWVDDSFGSCSEMIYLLKEKLNLNLTFKGALAIYVGLITDTGNFRYHRVSAQTLRIASELLNYGIDVALVEQNINKVTLNFLKYQGYICQNIIACDGFAYVYVNQQIIEQFNITLEEVFLSINILSNIKNFPFYALFFERPDSKIQVRICSNGPQIYHIVQKYGCKGHLRACSMFLPSEKEILPFVATIKKEIAPFFKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPK8</accession>
    <name>Q6YPK8_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein RecA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">PAM_717</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_717"/>
    <dbReference type="EnsemblBacteria" id="BAD04802">
        <property type="protein sequence ID" value="BAD04802"/>
        <property type="gene ID" value="PAM_717"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_717"/>
    <dbReference type="eggNOG" id="COG0468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167234_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RECA_2" evidence="5">
        <location>
            <begin position="36"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="117" mass="12609" checksum="EA10F43937A8D0E4" modified="2004-07-05" version="1">MQNTQNKNDLEDTIKDIEKKFGKGSIMQFNSKTHKGIESISTGSLSLDIALEIGGYAKGRIIEIYSPESSGKTTLTLHAISEAQKKGGNVAFIDAEHALDPSYAKAIGVNLDKLLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-05-25" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPK9</accession>
    <name>Q6YPK9_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein RecA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">PAM_716</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_716"/>
    <dbReference type="EnsemblBacteria" id="BAD04801">
        <property type="protein sequence ID" value="BAD04801"/>
        <property type="gene ID" value="PAM_716"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_716"/>
    <dbReference type="eggNOG" id="COG0468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_189494_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RECA_3" evidence="5">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="88" mass="9665" checksum="774F5268E50D5066" modified="2004-07-05" version="1">MVVDSVAALVPEAELVGDMGNMAMGLQARMMGQSMRKQSGIINKTDTVVIYINQLREKTGMVFCNPEVTQGGKALKFFASLRLDIRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPN1</accession>
    <name>Q6YPN1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_694"/>
    <dbReference type="EnsemblBacteria" id="BAD04779">
        <property type="protein sequence ID" value="BAD04779"/>
        <property type="gene ID" value="PAM_694"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_694"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_959212_0_0_14"/>
    <dbReference type="OMA" id="PQERETQ"/>
    <dbReference type="OrthoDB" id="2113721at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-845-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="313" mass="35581" checksum="3D9B88A3E7C42EA1" modified="2004-07-05" version="1">MAKKIIIIKKTKKQQTTKKPTKNQRKLTPKTTKATIIKKTSTRITKSTPKTTKPIKQQRTTQPTKIIVETQQKQDNWFVKIIKSLKTTILILLPLTLIVGGIYWVLFKFFPEIFSQINDFTINAATKTKSLYDKITQPIRDFIEYIHNKATGNNQNPNQTPSRQNKLGYYLATTLSIIGICLGIGKIGNWLKGGTKKAIRKGTKKTIQKKATSKIANVGGKICKIGGKILFWVSIASTAYELYQFYQEGTRNPNPPQQLENKIENPNTHTPHHEEAIQTNNNVEEANQNTNNESQEDEPQERETQKKTNSQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPR1</accession>
    <name>Q6YPR1_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent 26S proteasome regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpt1</name>
        <name evidence="3" type="ordered locus">PAM_664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_664"/>
    <dbReference type="EnsemblBacteria" id="BAD04749">
        <property type="protein sequence ID" value="BAD04749"/>
        <property type="gene ID" value="PAM_664"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_664"/>
    <dbReference type="eggNOG" id="COG0464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1766145_0_0_14"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-809-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="147" mass="16522" checksum="7740F39DAC3E1ABE" modified="2004-07-05" version="1">MLLYGVPGTGKTFFANCFMKDTNFKYVAKCTGADFAQKYVGESVKAVHSLFDSARKIADEHSGAIIFVDECEDVFVDLTQIREHHKGQSEAVTAFKEELTSEKNNPTKPIFLIAATNYLDKMDDAIKSRFTYKIEVKPSKKNHAKTL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-12-12" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPV2</accession>
    <name>RS21_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsU</name>
        <name type="ordered locus">PAM_623</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPV2"/>
    <dbReference type="SMR" id="Q6YPV2"/>
    <dbReference type="STRING" id="262768.PAM_623"/>
    <dbReference type="PRIDE" id="Q6YPV2"/>
    <dbReference type="EnsemblBacteria" id="BAD04708">
        <property type="protein sequence ID" value="BAD04708"/>
        <property type="gene ID" value="PAM_623"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_623"/>
    <dbReference type="eggNOG" id="COG0828">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159258_3_2_14"/>
    <dbReference type="OMA" id="RFHETPI"/>
    <dbReference type="OrthoDB" id="2088764at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-758-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="PTHR21109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_0000266720" description="30S ribosomal protein S21">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="57" mass="6901" checksum="CE89A21226E2B219" modified="2004-07-05" version="1">MPKTVFRKGETIEETLRRFKREVSKSGVLAEARRKEHYIKPSVQKKNRQKNMRSKKR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2006-03-21" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPW7</accession>
    <name>RNC_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribonuclease 3</fullName>
            <ecNumber evidence="1">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ribonuclease III</fullName>
            <shortName evidence="1">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rnc</name>
        <name type="ordered locus">PAM_608</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease III family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YPW7"/>
    <dbReference type="SMR" id="Q6YPW7"/>
    <dbReference type="STRING" id="262768.PAM_608"/>
    <dbReference type="PRIDE" id="Q6YPW7"/>
    <dbReference type="EnsemblBacteria" id="BAD04693">
        <property type="protein sequence ID" value="BAD04693"/>
        <property type="gene ID" value="PAM_608"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_608"/>
    <dbReference type="eggNOG" id="COG0571">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000907_1_3_14"/>
    <dbReference type="OMA" id="LTHKSCK"/>
    <dbReference type="OrthoDB" id="1890943at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-734-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000228558" description="Ribonuclease 3">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="1">
        <location>
            <begin position="4"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="1">
        <location>
            <begin position="154"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="238" mass="26841" checksum="9717ACEB1FF3AEC5" modified="2004-07-05" version="1">MKNIQTLFQTLNITPQNLTLYKQALTHSSYSNEQNPPQEDNERLEFLGDAIVGLLMADYLYSQSKEDEGIMTKKRAQAVCERSLTIYAHNIELQNYLLLGKGEKNKDFNAKSIIADTFEALFGAIYLDLGYLTAKKVFHNIVLPHLAKTIYIIDFKTQLQEIVQSEKKTIQYKIVQEQGPAHSKNFVAEVYLEKNLLGTGEGSTKKAAEQKAAQQALSKVAKPKDLLNNKGGKEKELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YPY4</accession>
    <name>Q6YPY4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dnaE</name>
        <name evidence="10" type="ordered locus">PAM_591</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_591"/>
    <dbReference type="EnsemblBacteria" id="BAD04676">
        <property type="protein sequence ID" value="BAD04676"/>
        <property type="gene ID" value="PAM_591"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_591"/>
    <dbReference type="eggNOG" id="COG0587">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001600_4_2_14"/>
    <dbReference type="OMA" id="MMREYIL"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PHP" evidence="7">
        <location>
            <begin position="8"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_alpha" evidence="8">
        <location>
            <begin position="275"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_finger" evidence="9">
        <location>
            <begin position="529"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAD04676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="625" mass="72548" checksum="BF5A94E78713AAFC" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ04</accession>
    <name>Q6YQ04_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SF4 helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_571"/>
    <dbReference type="EnsemblBacteria" id="BAD04656">
        <property type="protein sequence ID" value="BAD04656"/>
        <property type="gene ID" value="PAM_571"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_571"/>
    <dbReference type="eggNOG" id="COG0305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1160155_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="239" mass="27870" checksum="F1C2D89B1A5EABFA" modified="2004-07-05" version="1">MTLEENLSRLLAHQTQIPLDVILAKNWEDSNITQHTYMERMNDAQKFFSQLNLSFSYDQTKKIDYIIDLVYRLHLEKQIEIIVIDHLQITKASNHLENDRLAIDEIMTKLKQLAMELNIVIIILSQFSRDTYSHYQGKSPEITALKGSGGIETNSDIVLMMSEFQPKLSKDQEKPLNIYNQNCNQLYLASKNNKSEKIIELSIKKNRSGTKKNLVYHFEMSTQTFQEIGYVLPYPLESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2021-09-29" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ23</accession>
    <name>Q6YQ23_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dTMP kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">PAM_552</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_552"/>
    <dbReference type="EnsemblBacteria" id="BAD04637">
        <property type="protein sequence ID" value="BAD04637"/>
        <property type="gene ID" value="PAM_552"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_552"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1946601_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="4">
        <location>
            <begin position="6"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAD04637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="138" mass="15937" checksum="3FC888E6DC992248" modified="2004-07-05" version="1">MKLIVFEGLDGSGKTTLIQKVRKQLEKQGQEVITLQGLGSSSIGQPLRDIFLTNAQLKPLTRYLLSFANMQQIQEEEIKPHLETNKIILIDRWLGSNFAYQAYPRNIDKNYQLFNLLNKQFIKPDMTLFISKSNHNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ28</accession>
    <name>Q6YQ28_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tra5</name>
        <name evidence="2" type="ordered locus">PAM_337</name>
        <name evidence="3" type="ordered locus">PAM_547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Onion yellows</strain>
            <strain evidence="4">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_337"/>
    <dbReference type="EnsemblBacteria" id="BAD04422">
        <property type="protein sequence ID" value="BAD04422"/>
        <property type="gene ID" value="PAM_337"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04632">
        <property type="protein sequence ID" value="BAD04632"/>
        <property type="gene ID" value="PAM_547"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_337"/>
    <dbReference type="KEGG" id="poy:PAM_547"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_4_3_14"/>
    <dbReference type="OMA" id="WSISNSM"/>
    <dbReference type="OrthoDB" id="1637053at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-403-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-657-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="151"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="309" mass="37119" checksum="72C2FDF8B8F918CB" modified="2004-07-05" version="1">MQKLKQKINLLQQIIKKIEKIDKKIIFNLVEKFQNVLNLTTILKTIQTKRSTYYYWLKVNHKIKIKQEQYLLKQKRIESLCKMHEYLFGHRKITHLYQKIFNEPITKKKVYFIMKEKGICCRLRSKKNKYHYQQLKSQLKIVPNLINQDFKTYKPMQKLFTDITYFKTPQGFLYFSCIIDSFNNQIVASHVSNHQNKNLVLNTIKKMPKLKKPCIIHSDQGSVYQSLKIQHTLTKKGFLISMSRKAAPRDNAVIKNFFGQMKSILFYRDPFLFQNPMTKMKTIINQFPAFWNKKWILDKLNYLSPIQYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ85</accession>
    <name>Q6YQ85_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type amino acid transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">artM</name>
        <name evidence="7" type="ordered locus">PAM_490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_490"/>
    <dbReference type="EnsemblBacteria" id="BAD04575">
        <property type="protein sequence ID" value="BAD04575"/>
        <property type="gene ID" value="PAM_490"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_490"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_1_14"/>
    <dbReference type="OMA" id="EMFAQGK"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-576-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="26"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="244" mass="27694" checksum="A0FA5D189573B131" modified="2004-07-05" version="1">MSNIFNWFNLLKRLLKIYYPLYKEGFDTTFKIALFGTIGAFIVSLCVLYIKGIITLNKHTKMSLKKQYFFKILDKSINVYIFIIKSIPMMLQAMFFHFGLKGTGYFKWLTPLQSGLFVIIFNSAAYLAEVMIKNMEFFDSGQIEASLSLGMTQTQTFKKVVCPQVVRKSLLRISNEFIVNIKDSSVFGVIGINELYNAGSTVNASVASANAKILALIVPVFVYLVLVLLVSLLLKKIEKINDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQ94</accession>
    <name>Q6YQ94_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_481"/>
    <dbReference type="EnsemblBacteria" id="BAD04566">
        <property type="protein sequence ID" value="BAD04566"/>
        <property type="gene ID" value="PAM_481"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_481"/>
    <dbReference type="HOGENOM" id="CLU_1625396_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="163" mass="19469" checksum="6B71DA987DFAB6C2" modified="2004-07-05" version="1">MSMLKGIEKANKGKKPSFEYDDLFSKTVRFLNIIDSLSKDESLKHQFEKEEPNLQSRSLQNDKLDKLLQDRANDRYLPPIRNPQEQNAFINKFKQIFMDEEFQEDESKPEPAFIQTFKKNQFFNKNKSESESELNNWDTIKKFNPNFQYLNLDQYCLEPNTPQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-02-15" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQC1</accession>
    <name>END4_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable endonuclease 4</fullName>
            <ecNumber evidence="1">3.1.21.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Endodeoxyribonuclease IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Endonuclease IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nfo</name>
        <name type="ordered locus">PAM_454</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.</text>
            <dbReference type="EC" id="3.1.21.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 3 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.2" evidence="1"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YQC1"/>
    <dbReference type="SMR" id="Q6YQC1"/>
    <dbReference type="STRING" id="262768.PAM_454"/>
    <dbReference type="EnsemblBacteria" id="BAD04539">
        <property type="protein sequence ID" value="BAD04539"/>
        <property type="gene ID" value="PAM_454"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_454"/>
    <dbReference type="eggNOG" id="COG0648">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025885_4_1_14"/>
    <dbReference type="OMA" id="HPGSHLK"/>
    <dbReference type="OrthoDB" id="1088517at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-538-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008833">
        <property type="term" value="F:deoxyribonuclease IV (phage-T4-induced) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00152">
        <property type="entry name" value="Nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="PTHR21445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00587">
        <property type="entry name" value="nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00729">
        <property type="entry name" value="AP_NUCLEASE_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00731">
        <property type="entry name" value="AP_NUCLEASE_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000190862" description="Probable endonuclease 4">
        <location>
            <begin position="1"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00152"/>
        </source>
    </evidence>
    <sequence length="292" mass="33082" checksum="5BADAC30E2B8F833" modified="2004-07-05" version="1">MLFLGSHVAMKKPHNFQGAIQTAISYGANALMVYSGAPQNTIRTKTEELKIKQALEIVQNNNLSLNNLVGHAPYIINLANPDETKRAFAIDFLSQELERFAAMKINKMVLHPGNYLKTNPQEGISLIAQSLDLIFEKTKHLKTQVALETMAGKGTEIGKNLEELQQIRTQVKNNTRVSFCLDTCHLFDAGYDLKENLEEIIQKIDSILGFQNISVIHINDSKNECNSHKDRHENIGFGKIGFETLLKIIYHRAFACIPKILETPYINDKAPYKREIEMIKAKAFNPELKKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQF5</accession>
    <name>Q6YQF5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_418"/>
    <dbReference type="EnsemblBacteria" id="BAD04503">
        <property type="protein sequence ID" value="BAD04503"/>
        <property type="gene ID" value="PAM_418"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_418"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060940_0_0_14"/>
    <dbReference type="OMA" id="YRIKEPP"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-504-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="383" mass="45178" checksum="A16DBDF7C61B152A" modified="2004-07-05" version="1">MITLTLIEKIFICFLCVFIGFGFANIIYQPPKYDFIQPVNSTDKNNVFLSVEQSSNKNTELKKFNSAFKLSSKEIDNYFYDKIIPIKEKEIDNMKCYNVHLGENSNIKDALGWLHYHFPNKNFKSNFSYALYNNNSLNNEIDFQYRIKEPPPKDFLLAYFDGGTRDGKNNIYNLDTLTQMGNGASDLYFFWSNNRPYIPESTTFTPENYHLEIIYDKGTNYGGPSYLAIDKIIIKDIQKDKIVAVYPINQKIEEPFYIHNYDFVLKFPFYNYIQEGMLWSNSHIKSLKKLIYMKNALDKIVLYIMMLNKKIEKKGTNMKLKQIYLNLLVVCGFAILGLWIYGFFLKKYNNNNLFQNNHPPTEQNQSFEGISKYLEYCRRLKNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQG2</accession>
    <name>Q6YQG2_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04496">
        <property type="protein sequence ID" value="BAD04496"/>
        <property type="gene ID" value="PAM_411"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_411"/>
    <dbReference type="HOGENOM" id="CLU_1592911_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-496-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="167" mass="19785" checksum="A1875A5EE85AA01B" modified="2004-07-05" version="1">MIEGFEVLEMKINNDDFVNFDKVTNLTQILFNSKKLSEEKITNYRKNIKTIIEKLCLYFETNLIYLTNENFEIGEYGFESIKNKISLNFPNNKFLIFLECENNDVSQKGFYSKLTWQVLKIFNEVEYKINDFEINFIVSTDDIKLIDSNIRAKFCHNEISPNKNSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQG5</accession>
    <name>Q6YQG5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase sigma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpoD</name>
        <name evidence="2" type="ordered locus">PAM_408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_408"/>
    <dbReference type="EnsemblBacteria" id="BAD04493">
        <property type="protein sequence ID" value="BAD04493"/>
        <property type="gene ID" value="PAM_408"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_408"/>
    <dbReference type="eggNOG" id="COG1191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110732_0_0_14"/>
    <dbReference type="OMA" id="NTHQIWL"/>
    <dbReference type="OrthoDB" id="1857862at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-490-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="23"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="199" mass="23558" checksum="499DF3BCF869F0ED" modified="2004-07-05" version="1">MLREKLFKDFLKSKKNLEMRNQLIDLHLSLVKKLVSKFKYYPCVLPKQDLYQEGVLGLIKALNNYVDLGYDFIAYATPTIKSEIRELIRKSHSPCIPQKTHKTNNPSFQEEKHTWHYQILNPNQLWLKQIHHALFLKKLKTKLNKKEFNVIRLNFGVPLGNINEDYQPSYSNQEITQILNLTLRQVENIKNIAINKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2020-02-26" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQG6</accession>
    <name>Q6YQG6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_407</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04492">
        <property type="protein sequence ID" value="BAD04492"/>
        <property type="gene ID" value="PAM_407"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_407"/>
    <dbReference type="HOGENOM" id="CLU_1319854_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="184" mass="21889" checksum="8ADBC867F6B5FBF0" modified="2004-07-05" version="1">MQTLKQDLINLTIIAHSKKKNTYQEANYRPKNQTLFVDSQILEEIKQTKITLINDNFSSINSKLLLSDLTPLKSQNNHLKHLYPLFQINYKNETKNHIKELIGKIDLHKLETLQLYQIDPQKLDKYNNPMKTNYKKGLNIIYYRKEDLKYLQSFLTKDKQGYRVKKLRSGYLSNLNKKELKTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQK6</accession>
    <name>Q6YQK6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">PAM_327</name>
        <name evidence="4" type="ordered locus">PAM_367</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">Onion yellows</strain>
            <strain evidence="5">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04412">
        <property type="protein sequence ID" value="BAD04412"/>
        <property type="gene ID" value="PAM_327"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04452">
        <property type="protein sequence ID" value="BAD04452"/>
        <property type="gene ID" value="PAM_367"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_327"/>
    <dbReference type="KEGG" id="poy:PAM_367"/>
    <dbReference type="HOGENOM" id="CLU_959212_0_0_14"/>
    <dbReference type="OrthoDB" id="2121724at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-388-MON"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-436-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAD04412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAD04452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="287" mass="32871" checksum="DBDBDE28D5576917" modified="2004-07-05" version="1">MSKKIIETKKNQSKNNNKTNKNTKNKSKNNKSNKIIIKRKTPTHKIIIETQTKKENWLFKITKTFFKILIWCIPLLLIGGAIYWTFFKFFPEVLNQINAFTSNAVTKTKMLYDKATQPIRKVIEYIYNKVTGNDKDPNHTPSPQNKLGYYLATTLSVIGICFGIGKVGHWLKSGKKKTIKKGTKTIIQKKATSKIANVGGKILKIGSKVLFWVSLASTAYELYQFYHEETKTPNPPQQLTHKMENPSTPISQTPSIQQSFNPTIIENEESTLTNNNEVKEETNQEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQL5</accession>
    <name>Q6YQL5_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">PAM_358</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">OY-M</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3"/>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="REBASE" id="7518">
        <property type="entry name" value="M.PhsOYORF358P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAD04443">
        <property type="protein sequence ID" value="BAD04443"/>
        <property type="gene ID" value="PAM_358"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_358"/>
    <dbReference type="eggNOG" id="COG0338">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140323_0_0_14"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023095">
        <property type="entry name" value="Ade_MeTrfase_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAD04443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="159" mass="19045" checksum="9FE623111A3C3434" modified="2004-07-05" version="1">MKINWIGCKKKLLPQIISHLPKQFKTYYEPFLGSGVLYFYLQPSKAILNDNDHQLITMWKQSLQNPDHFVNKVKAIENYIYQYNNQKNQKQAFKHLLNQYNQNVKKRKKLTRSAIFYVLNKYAFRGITRYDKQSNLKTNFGYKSKQKTPIINLNELVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YQS6</accession>
    <name>Q6YQS6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_297"/>
    <dbReference type="EnsemblBacteria" id="BAD04382">
        <property type="protein sequence ID" value="BAD04382"/>
        <property type="gene ID" value="PAM_297"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_297"/>
    <dbReference type="HOGENOM" id="CLU_2119763_0_0_14"/>
    <dbReference type="OMA" id="DAKYNNY"/>
    <dbReference type="OrthoDB" id="1901026at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-355-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025982">
        <property type="entry name" value="SieB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14163">
        <property type="entry name" value="SieB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="115" mass="13885" checksum="CF096C6966242E9B" modified="2004-07-05" version="1">MFESIFFKFIFIVFICLLVIFIMNYFYRKNVKNKIINYLLSCSNLEQEILKSFLQNPHKTFPLTKDANITKNLLQLNIIFLKEIVSDAKYNNYVFNPLIKKIIHKNKDLKKIYHE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2004-08-16" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR16</accession>
    <name>RL22_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplV</name>
        <name type="ordered locus">PAM_205</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="1">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR16"/>
    <dbReference type="SMR" id="Q6YR16"/>
    <dbReference type="STRING" id="262768.PAM_205"/>
    <dbReference type="EnsemblBacteria" id="BAD04290">
        <property type="protein sequence ID" value="BAD04290"/>
        <property type="gene ID" value="PAM_205"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_205"/>
    <dbReference type="eggNOG" id="COG0091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083987_3_3_14"/>
    <dbReference type="OMA" id="KRIQPRA"/>
    <dbReference type="OrthoDB" id="1666043at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-251-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_L22/L17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_0000125192" description="50S ribosomal protein L22">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <sequence length="129" mass="14269" checksum="A403DCA8BAFEB803" modified="2004-07-05" version="1">METQNAKAIARKISIAPRKARLVVDLIRGKNIAQAQAILTFTPKVAAPVILKLLNSAVSNAVNNLKLNREQLYVKEVFVNEGLRLKRMFPRAKGSGDMIKKRTSHITLVITSSTNLQTSKEEEQSGSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR31</accession>
    <name>Q6YR31_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zn-dependent carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_187</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_187"/>
    <dbReference type="EnsemblBacteria" id="BAD04272">
        <property type="protein sequence ID" value="BAD04272"/>
        <property type="gene ID" value="PAM_187"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_187"/>
    <dbReference type="eggNOG" id="COG2317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032916_1_1_14"/>
    <dbReference type="OMA" id="EFGHALY"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001333">
        <property type="entry name" value="Peptidase_M32_Taq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217">
        <property type="entry name" value="PTHR34217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02074">
        <property type="entry name" value="Peptidase_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00998">
        <property type="entry name" value="CRBOXYPTASET"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="385" mass="44814" checksum="06483D287D7F1A83" modified="2004-07-05" version="1">MWRQAKKNNDYNSFKPYFQKVLNYTKEVANLRSQKLGVSLYDALIDQYDPGMTATKIKQIFNVIKEKLPPLMKTILQKQEQEKHLYKDIAMTLENQKKLNQIIMPKIGFDCNYGRLDESIHPFCGGTPYDVRLTSNYNANNFLDSFLATIHEVGHGLYAQNLPQQYKNQPVGTPRSFSFDESQSLLMEKQVAKSQEFLTYLVNILKTELNFYNPSLTPQNLFKQANQVKPDFVRIYADEVTYPFHVILRFEIEELLISDQLSLDDLPHFWNCKMKEYLGITPPNVGLGCLQDIHWPQGSFGYFPSYLNGAILASMIMKNVQKANPNIKEGFETGKFETLNQYLDQKIRNWGSFYINQEFVFKATGMPQINPETFLQYLENKYLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR38</accession>
    <name>Q6YR38_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-type cobalt transport system, permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cbiQ</name>
        <name evidence="6" type="ordered locus">PAM_180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">OY-M</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_180"/>
    <dbReference type="EnsemblBacteria" id="BAD04265">
        <property type="protein sequence ID" value="BAD04265"/>
        <property type="gene ID" value="PAM_180"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_180"/>
    <dbReference type="eggNOG" id="COG0619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_882546_0_0_14"/>
    <dbReference type="OMA" id="RIKHLRF"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAD04265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="349" mass="40950" checksum="858930787B3DD5F8" modified="2004-07-05" version="1">MMKNNDFTNNNLSHPSLSRCFLYQLHPSIKILAFVLLLVFILKLPINVENIAPNQVFIFANPKRITLFYLFCVVALMSLCFFFGVTWSYFWQRIKHLRFVFIISLVINLVPSEDTSFNAFMRAQIPILSYDAIHSFWLFLICILLYNFTKKYIPFKLSYLLFLLLCVFVIPSYFPSNIQEILGCKLKNYILQTTSFLRICFIMTRLFLIVMLFFLFNKITSFIEIQDGLDIILSPLKKLKISTETFTLMLSLIFMANSFLLQETNKILKAQTARGMDLHKKNIFKRINHLLALLVPIFVLVFKRSLVLSNAMEVRGYVLGAPRTKMITYRWKMLDFITITTIFALLFIK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-03-15" modified="2022-05-25" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YR70</accession>
    <name>SSRP_ONYPE</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">smpB</name>
        <name type="ordered locus">PAM_146</name>
    </gene>
    <organism>
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>OY-M</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SmpB family.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q6YR70"/>
    <dbReference type="SMR" id="Q6YR70"/>
    <dbReference type="STRING" id="262768.PAM_146"/>
    <dbReference type="EnsemblBacteria" id="BAD04231">
        <property type="protein sequence ID" value="BAD04231"/>
        <property type="gene ID" value="PAM_146"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_146"/>
    <dbReference type="eggNOG" id="COG0691">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108953_0_1_14"/>
    <dbReference type="OMA" id="WTNHSAR"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <feature type="chain" id="PRO_0000102998" description="SsrA-binding protein">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <sequence length="152" mass="17860" checksum="A59802F55487C8D2" modified="2004-07-05" version="1">MKTIITNKKAFYDYSLEKKKYQAGIKLLGSEVKSIRIGKINLLNSYIHIKNEEAFIVNMTILKYPFSCCLAYDENRTKKLLLQKHEIIQIKNKIKTEKLSVIPLKVYFNKNLVKLEIALSKGKKQHDKRNALKDFDAKLRIQKTLKNFNQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRD5</accession>
    <name>Q6YRD5_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">PAM_080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_080"/>
    <dbReference type="EnsemblBacteria" id="BAD04165">
        <property type="protein sequence ID" value="BAD04165"/>
        <property type="gene ID" value="PAM_080"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_080"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2570447_0_0_14"/>
    <dbReference type="OrthoDB" id="1637053at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-108-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAD04165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="81" mass="9468" checksum="B426D9EDDED86CDA" modified="2004-07-05" version="1">MQYYNEEMILNRQFLNLAKNMKATRPHQILCGGITEVYYHDKVLYVSVVLDTYSRKILAYHVSYYEGASLIIGTVDKLNVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="121" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRF6</accession>
    <name>Q6YRF6_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC-type multidrug/protein/lipid transport system, ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mdlB</name>
        <name evidence="11" type="ordered locus">PAM_059</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">OY-M</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_059"/>
    <dbReference type="EnsemblBacteria" id="BAD04144">
        <property type="protein sequence ID" value="BAD04144"/>
        <property type="gene ID" value="PAM_059"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_059"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_14"/>
    <dbReference type="OMA" id="MSVMMAT"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-77-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="16"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="332"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="366"/>
            <end position="373"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAD04144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="574" mass="65547" checksum="A692E8D418BD7FDE" modified="2004-07-05" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2004-07-05" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q6YRH9</accession>
    <name>Q6YRH9_ONYPE</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">PAM_036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Onion yellows phytoplasma (strain OY-M)</name>
        <dbReference type="NCBI Taxonomy" id="262768"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Tenericutes</taxon>
            <taxon>Mollicutes</taxon>
            <taxon>Acholeplasmatales</taxon>
            <taxon>Acholeplasmataceae</taxon>
            <taxon>Candidatus Phytoplasma</taxon>
            <taxon>Candidatus Phytoplasma asteris</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2004" name="Nat. Genet." volume="36" first="27" last="29">
            <title>Reductive evolution suggested from the complete genome sequence of a plant-pathogenic phytoplasma.</title>
            <authorList>
                <person name="Oshima K."/>
                <person name="Kakizawa S."/>
                <person name="Nishigawa H."/>
                <person name="Jung H.-Y."/>
                <person name="Wei W."/>
                <person name="Suzuki S."/>
                <person name="Arashida R."/>
                <person name="Nakata D."/>
                <person name="Miyata S."/>
                <person name="Ugaki M."/>
                <person name="Namba S."/>
            </authorList>
            <dbReference type="PubMed" id="14661021"/>
            <dbReference type="DOI" id="10.1038/ng1277"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">OY-M</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP006628">
        <property type="protein sequence ID" value="BAD04121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="262768.PAM_036"/>
    <dbReference type="EnsemblBacteria" id="BAD04121">
        <property type="protein sequence ID" value="BAD04121"/>
        <property type="gene ID" value="PAM_036"/>
    </dbReference>
    <dbReference type="KEGG" id="poy:PAM_036"/>
    <dbReference type="HOGENOM" id="CLU_1254884_0_0_14"/>
    <dbReference type="BioCyc" id="OYEL262768:G1G26-51-MON"/>
    <dbReference type="Proteomes" id="UP000002523">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAD04121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002523"/>
        </source>
    </evidence>
    <sequence length="220" mass="25033" checksum="1936492DEA3BBA21" modified="2004-07-05" version="1">MWQKDKNLKPSIDELQNLLQKETNVAHHNTKLNDLEIKDVSPDCCLQIDEKDFCNPQVSINKIKKNLLEQIEKALHEKFQNLENNIEITAMKIENRFDQIKKVYYLRNFIIKSSYLKSNLTPQSDPPQLLDDSASENSQGETSSVSSVSLPGTQPSTLNPSAQEQSSTPSPNPEAQPNQANTNTSQENEKNRLNCQLMLVKCLMKIKMPPPLMSLYNFLC</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>